LOCUS       NZ_CDME01000002        21101 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Kibdelosporangium sp. MJ126-NF4, whole genome shotgun sequence.
ACCESSION   NZ_CDME01000002
VERSION     NZ_CDME01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium sp. MJ126-NF4
  ORGANISM  Kibdelosporangium sp. MJ126-NF4
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-2014) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000826545.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:10:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,648
            CDSs (total)                      :: 10,573
            Genes (coding)                    :: 10,470
            CDSs (with protein)               :: 10,470
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 19 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 5 of 103
            Pseudo Genes (multiple problems)  :: 10 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1369755
            Orig. end                         :: 1390856
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CDME01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21101
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21101
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21101
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11101](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11101)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(160..1689)
                     /locus_tag="BN1199_RS06230"
     CDS             complement(160..1689)
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223211.1"
                     /locus_tag="BN1199_RS06230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_042179708.1"
                     /transl_table=11
                     /translation="MPSEVVLDARAVGKRFPGVVALSEVDLTLLAGEVHALVGENGAGK
                     STLIKVLTGVHPPDSGELVHQGEPVRFGRPLDAQAAGISTVYQEINLVPLMSVASNLFL
                     GREPRTRFGLLDYRAMNTAAAKLLRSYGIDVDVTRPLRTLGAGVRQMVAVARAAATDAR
                     VVILDEPTSSLEPREVDTLFKIVEQVRASGAAVLYVSHRLDELYRICDAVTVLRDGRKV
                     HSGPLAELPRLQLVALMLGRDLEQIRREGTTKFDSAPTETVETPVLAARGLTSQHRLHG
                     VDVTVRPGAIVGLGGLLGAGRSETVRAIAGSLPVDEGTVTVAGKPVRSGSVAAAMRAGV
                     VMLPEDRKADGILPDLSVRENIVLAALPRLSAAGLVSRGRQDAIVDTFMKRLRIKASGP
                     DQKVGELSGGNQQKVLLARLLCREPKVLLLDEPTRGIDVGAKAEVQALVAELAAAGLGV
                     VLISSEFEEVVEGSDSVVVLREGRVVAELRGADVTERKLIAALADGGEGDG"
     gene            complement(1689..2780)
                     /locus_tag="BN1199_RS06235"
     CDS             complement(1689..2780)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662236.1"
                     /locus_tag="BN1199_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_042179710.1"
                     /transl_table=11
                     /translation="MAAATQSRPVHLGRILGASLCGVALVLSGCAKSEETPTLPAQGTG
                     GAQAPVAPATDGPTCTLQQYGGDKVDLKNAVVGFSQSEKEANPFRIAETQSIKDEAAKV
                     GVRQLLTTNANSQLSKQISDIQDMINKGAQALIVAPLNSDGLEPALSAARARNIPVLTI
                     DRKVNSSPCKDYVAFLGSNFVEQGKRAAKEMAKALNNKGKVAILLGASGNNVTTDRTAG
                     FVDELKASAPEIQVVAQQTGEFAREKGQQVMEQIIQAQPDINGVYAENDEMALGALVAL
                     RGANKKAGTDIRVVSIDGTRNAVQKVVDGELSAVVESNPRFGPLAFQTLESYFGGKPVQ
                     QNVVISDKLYNKDNAAAELGNAY"
     misc_feature    complement(2745..2747)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    2834..2851
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.55"
                     /tool="antismash"
     gene            2880..3875
                     /locus_tag="BN1199_RS06240"
     CDS             2880..3875
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635799.1"
                     /locus_tag="BN1199_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_042179712.1"
                     /transl_table=11
                     /translation="MATLKDVAELAGVSVKTVSNVVNGYSFVKPENERRVREALAATGY
                     KPNVGARNLRRGRTGFIALMVPELSIPYFGELAGGVITAAHTHDWSVLIEQTHGLRDPE
                     VSTLASLGPHMVDGAIISPEALHTQDFTRNPTDVPMVLLGEHSLDVPIDHVGIDNVQAA
                     RIAVRHLVDLGRTRIAVVGQNPNRGTAAQRLAGYHSALADAGLPSPPDYIAPAARYHHR
                     DGAEAMARLLALPEPPDAVFCFNDMLAHGAVRAAAERGYQVPGDIAVVGFDNTEHSAYS
                     LPSLTTIAPDKAALAKAAVDLVHERASGDVSPVRDVQIPFTLQVRESTAG"
     misc_feature    complement(2923..2937)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            4051..4458
                     /locus_tag="BN1199_RS06245"
     CDS             4051..4458
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037950.1"
                     /locus_tag="BN1199_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bacteriophage spanin2 family protein"
                     /protein_id="WP_042179714.1"
                     /transl_table=11
                     /translation="MRSTKRLLTGVLGGGALVIALTGCDAVKGAQQAAEGASNAASTVQ
                     VCAEALKIAAFNPDTANPEAAAQGAKDAGQKLSDLAGKATNTTVNQALTDLSTTFKETT
                     ATDVVNGSTNWIKTKADQVAALTKACTSTGG"
     gene            4496..5095
                     /locus_tag="BN1199_RS06250"
     CDS             4496..5095
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042179716.1"
                     /transl_table=11
                     /translation="MSFNAFANHVRNPALPFGRRVVALRCCVQLYRPIGYHATLGYLAI
                     LAGPFQHEEAALLRALDALSASRASWHADLEQYAQVRRVAKRKGQRSPRPRDPNPNTGP
                     HYWYGAPQKAAAYALLTWRGQNHGVVSRFSSLVDSSLAADGALTPAQRDRLDFEVDMVR
                     RSIRAGLYSIDYAAYGYARELLVVAHHLRIAADYSS"
     gene            complement(5132..5626)
                     /gene="msrA"
                     /locus_tag="BN1199_RS06255"
     CDS             complement(5132..5626)
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165919.1"
                     /locus_tag="BN1199_RS06255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_232327843.1"
                     /transl_table=11
                     /translation="MTKVAVLAGGCFWGMQDLIRRQPGVVATRVGYTGGHVANATYRNH
                     DGHAEAIEITYDPEQTSYRRVLEFFFQIHDPTTRDRQGNDIGSSYRSAIFYADEEQKQL
                     AEQTIADVEASGLWPGKVVTEVSQLGDFWEAEPEHQDYLEHYPNGYTCHYIRPDWKLTT
                     S"
     gene            complement(5628..6482)
                     /locus_tag="BN1199_RS06260"
     CDS             complement(5628..6482)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="BN1199_RS06260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_232327844.1"
                     /transl_table=11
                     /translation="MNAQAVVVERTYPRPIMAAFHAMWSVGGALAATVGAALLGAGVPT
                     EVSMSTCGVLVVIISLATARFLLEPDHQQADNEGEPAGKAATGGKLVWLLGLLAFALML
                     GEGVAADWAALHSKDLLGTSASTAAFAFGSFSAAMTVGRFATDRVAAIIGPVAIVRYGS
                     ALATVGLTVVTVSQWVPLSLAGWMLFGLGLSGGVPQLFTAAGNLDTRSAGTLMARVVGL
                     GYVGILAGPALVGGLTHWVPLNVAFVLPIVLCALAAVFAYVMPGTKHAADALEQSESGR
                     EER"
     gene            complement(6543..6839)
                     /locus_tag="BN1199_RS57950"
     CDS             complement(6543..6839)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS57950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_232327845.1"
                     /transl_table=11
                     /translation="MTQLAAPPARAARVATWIYFTLNGFSVGLWVVHIPNVERATGISH
                     STLGLLLLLLGGAAFVGMQVGGAVADRIGQRKLVPAAGVLMGCALFGPGLADS"
     gene            6893..7480
                     /locus_tag="BN1199_RS06265"
     CDS             6893..7480
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801783.1"
                     /locus_tag="BN1199_RS06265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_052477788.1"
                     /transl_table=11
                     /translation="MTGYPKGRQRREDITTAAIEVYRETGYHGSSLREVAKRAGITHAG
                     LLYYFPTKEALLAAVLERRDAEDAEREKLDIPPGIDLLRHLIALAEYNVAHRGIVEVYA
                     RLAAEAIAPDHPAHEYFIRHYRIARDGAVATFAALAESGQLRDGVDPRAAAAAFIAMED
                     GLQVQWLTTPDEVDLVGSLRFFLQNLLTVPLD"
     gene            complement(7477..8571)
                     /locus_tag="BN1199_RS06270"
     CDS             complement(7477..8571)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658468.1"
                     /locus_tag="BN1199_RS06270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_042179720.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.3e-20, bitscore:
                     71.3, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.9e-21,
                     bitscore: 73.3, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLGIGVIGAGVISDVYLTNLTSFPDVNVVRVADLDTARAQAQAD
                     KHGVPRAGTVADLLTDPQVELVVNLTIPAAHAEVGLAALDAGKHVWSEKPLALDRQSGR
                     KLLDRAAEKGLRVACAPDTLLGAGLQTARRAIDDGRIGEPRTVLALFQTPGPESWHPAP
                     EFLYQAGGGPLLDMGPYYLSSLVTLLGPIARVTGAGGQARPTRVIGSGPRAGTEFAVTV
                     PTSVTALVEFARGGSAQIVLSFDSALLRTGLLEVTGTGGVAVLPDPNYFEGPTTLHLPG
                     REQPQEVEAQGHTATRGTGVLELARAIRTGVPERASGALAYHVLDTMLAIDESISSGRT
                     VVVESSADIPPALPVDWDPYERTF"
     gene            complement(8568..9293)
                     /locus_tag="BN1199_RS06275"
     CDS             complement(8568..9293)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227640.1"
                     /locus_tag="BN1199_RS06275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_232327846.1"
                     /transl_table=11
                     /translation="MSVQLYSVRDEFAERPGEVLQRLAAIGFTQVEPYGLVENAAVLRT
                     GLRESGLTAPTAHAQLIDADQRAVFEVAAECGVSVVIDPFVPAEKWRGVDDIAATAKAL
                     NAAAAIAHEYGVTVGYHNHWWELESRIDGRSAFEVFADRLDPELVLEVDTYWAVAGGED
                     APALLRRLGDRVHAIHVKDGGLATDASGQVPAGQGRLAVADVLAAAPKALRVVEFDRYD
                     GDIFDGIAASFAYLQGRAG"
     misc_feature    complement(9327..9341)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 27.13"
                     /tool="antismash"
     misc_feature    9328..9342
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 23.69"
                     /tool="antismash"
     misc_feature    9338..9353
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.43"
                     /tool="antismash"
     gene            complement(9414..9845)
                     /locus_tag="BN1199_RS06280"
     CDS             complement(9414..9845)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS06280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157527288.1"
                     /transl_table=11
                     /translation="MNYTPADPAIDRLVTQERAVDPVPDDLAAMVDFALDHESPDAEFL
                     RPVSRHRNDRSRMLTFEGAGKTVLIAITEDADVTVRVDGWVAPAAACRVRLRTAAGVLE
                     VSASATGRFTYASVHRGLAQISLCRNRSVCSVATPTLVL"
     gene            complement(10001..11101)
                     /locus_tag="BN1199_RS06285"
     CDS             complement(10001..11101)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334399.1"
                     /locus_tag="BN1199_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_042179726.1"
                     /sec_met_domain="T1TS (E-value: 6.9e-49, bitscore: 164.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDILFGPSGLGTSAARVMSRLSHDPAYVEREWGDATAPPLYVPV
                     VERVNEPLAEEVNRRLVIWAGECGFEGENLELLGRAGFGKLAMLAHPDSDDPDHLLIAA
                     QMNAAWWAADDLYADDSEMGATPTALPPRLSLAMAAMDPPPPAGEFTGELESALGSDPV
                     LVSLRSGVEHIAQLGSAAQVQRVNYSTFAMFVSWNAYAAWRYTSEYPPAWEYLAARQHD
                     SFYTSMTLIDVVGGYEVPASVYYDPRVREAAFRAGTATVLVNDLYSVEKDAADETPVCN
                     MVLQIAADRACSIQEATEVTVDLHNTIVKDFEAGHRALQAIPSLELQRFLRGLRAWMGG
                     GFEWHATNPRYKSSGQQEQEPTSGTE"
     gene            complement(11119..11967)
                     /locus_tag="BN1199_RS06290"
     CDS             complement(11119..11967)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (89-245). E-value: 3.4e-10. Score:
                     30.4. Matches aSDomain:
                     nrpspksdomains_BN1199_RS06290_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101535.1"
                     /locus_tag="BN1199_RS06290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_042179728.1"
                     /transl_table=11
                     /translation="MATVQSTTGPVLRSDYQRSIAAYWNNEKDPVNLRLGDVDGLYHHH
                     YGIGDYDPSVLQAGDQAVIKEMHRLETAQADVLLDHLGSIGQSDRLMDAGSGRGGTSIM
                     ANHRFGCHVDGVSISEQQVAFANDQAQQRNVNDRVRFHFRNMLDTGFDTGSMRGIWSNE
                     TTMYVDLHDLFREFARLLEYGGRYVCITGCYNDVTGGRSRAVSQIDQHYICNIHPRSEY
                     FKALSDNGFVPINVVDLTAATIPYWELRAQSSVATGIEDPFLTAYKEGSFHYLLIAADR
                     I"
     aSDomain        complement(11233..11700)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS06290_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.40E-10"
                     /label="BN1199_RS06290_oMT.1"
                     /locus_tag="BN1199_RS06290"
                     /protein_end="245"
                     /protein_start="89"
                     /score="30.4"
                     /tool="antismash"
                     /translation="RLMDAGSGRGGTSIMANHRFGCHVDGVSISEQQVAFANDQAQQRN
                     VNDRVRFHFRNMLDTGFDTGSMRGIWSNETTMYVDLHDLFREFARLLEYGGRYVCITGC
                     YNDVTGGRSRAVSQIDQHYICNIHPRSEYFKALSDNGFVPINVVDLTAATIP"
     gene            complement(12188..12694)
                     /locus_tag="BN1199_RS06295"
     CDS             complement(12188..12694)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (11-167). E-value:
                     6.3e-21. Score: 67.2. Matches aSDomain:
                     nrpspksdomains_BN1199_RS06295_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950371.1"
                     /locus_tag="BN1199_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_042179730.1"
                     /transl_table=11
                     /translation="MEWTGARYADKPTVEVRTWIDASPDRVWAIVSDVGRMPDMSTELQ
                     SVRWLDDVSGPGLGHKFVGHSRHESFGEWSTTSEVVDFEPGRTFGWAVGDVAEPAAVWR
                     FHLRPQDGGTELAQWMQLGPGRSGLSAAIDRMPDKEQKIVFVRLREFERNMAATLAHIK
                     SAVEG"
     aSDomain        complement(12194..12661)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS06295_Polyketide_cyc2.1
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.30E-21"
                     /label="BN1199_RS06295_Polyketide_cyc2.1"
                     /locus_tag="BN1199_RS06295"
                     /protein_end="167"
                     /protein_start="11"
                     /score="67.2"
                     /tool="antismash"
                     /translation="PTVEVRTWIDASPDRVWAIVSDVGRMPDMSTELQSVRWLDDVSGP
                     GLGHKFVGHSRHESFGEWSTTSEVVDFEPGRTFGWAVGDVAEPAAVWRFHLRPQDGGTE
                     LAQWMQLGPGRSGLSAAIDRMPDKEQKIVFVRLREFERNMAATLAHIKSAVE"
     gene            complement(12736..13236)
                     /locus_tag="BN1199_RS06300"
     CDS             complement(12736..13236)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950372.1"
                     /locus_tag="BN1199_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_042179733.1"
                     /transl_table=11
                     /translation="MKRSSLGRWPCSIARTMDLLGDWWTPLVLREAFYGIRRFDDFQHG
                     LGIARNTLTDRLTRLVAEGLLDKQPYQDKPTRHDYVLTEKGRDFFGVLIAMTRWGDRWL
                     SSVDGPPVTMRHTGCGQDAHADVVCSACGEHLTSDDVTMRLGPGYPERLKALPEARRRF
                     PET"
     gene            complement(13233..14276)
                     /locus_tag="BN1199_RS06305"
     CDS             complement(13233..14276)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636955.1"
                     /locus_tag="BN1199_RS06305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_042179735.1"
                     /transl_table=11
                     /translation="MRTATTVEVSGDWHTQADFVDEAERLGLDVCFVAEAWGSDGPSVL
                     GYLAARTERILLGSGIFQLGTRTPVAIAQTAITLSNLSDGRFLLGLGASGPQVIEGLHG
                     VPFAKPLVRMRETVEIIRQVLDGGKIAYTGEAFHIPLPGGDSKPMRLSTRPAHRIPVYL
                     ATLSPAMLRLTGRVADGWLGTSFVPEGAEQAYFRHIDHGIAASGRTRADLDICQGAEVA
                     FAPDEDALRAMVADRRKELAFSLGGMGSASTNFYNQAYSRQGWADVAAEVRERWQAGDR
                     DGAAELVTDEMVLGTTLIGTDQMVRDRLRVWRDAGVDTVRLYPAGRTLDERLATLATAI
                     EMVREIG"
     misc_feature    complement(14365..14379)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.71"
                     /tool="antismash"
     gene            14419..16338
                     /locus_tag="BN1199_RS06310"
     CDS             14419..16338
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014625.4"
                     /locus_tag="BN1199_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_042179738.1"
                     /sec_met_domain="PIG-L (E-value: 4.8e-11, bitscore: 40.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHPPGHTRRPAVGAHKLPAWAKAAARPRARNRAAALPTTGSYVT
                     IVAHSDDELLFINPDLQPAIDAGLPVRTIYITADQNNGYPAGGLTREDLAAQLHEGTRN
                     GYAALTGQPRDWTIDTIVVADRIIERNTLDGAPHVQLLWINLPDGGDELHSEALMNLWN
                     DPNFVSPTIVPTGGPVTDVQEYTGEQLHNVLVELLALYQPTTIRIQDPAPDGRYGPEHI
                     DHIAASYHAHYAVRTYEGPDATGQCLLVRYRCYNTDLSPVNVFAPLYTPKAAAYGEYKK
                     LDPLTGNGFDAQLERNYQRFPVTEPFVIKDGTGALHAVIAGGDNVIAWRLNTGGATWSA
                     ATTLVSGQFAPGVAMELNADGTVQLAVLDLDSSTIMTTRQTAPGAGFGPWTSIGAPDGI
                     LGVPAFGRNSDNCLELYVLNEAGGLSNAYQETPNGTVFKGWDDVSGGPDILGQPTVWNS
                     ADNTLNIFADSNGKIRHWKQPPGGTTTVNAGFPAVETVGTPSPVVNTTGQGILIIREHG
                     DGTIGRSVEQTAAGTWSGLAHIGGQGGFGPTFGVRTSGTTPRVFAFARNDDYGISLNRQ
                     KANGTFDPNAWEDLGGYCEIGPAAVLDNAGLVRLLVVGGDCRLYERRQTTAGPSGAFTT
                     WQAV"
     gene            complement(16400..17272)
                     /locus_tag="BN1199_RS06315"
     CDS             complement(16400..17272)
                     /NRPS_PKS="Domain: Abhydrolase_1 (43-140). E-value:
                     4.1e-10. Score: 31.6. Matches aSDomain:
                     nrpspksdomains_BN1199_RS06315_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641838.1"
                     /locus_tag="BN1199_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_198151277.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.4e-09, bitscore:
                     34.6, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.1e-07, bitscore: 28.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTTHTLETTEVDLVYDVHGPQPTADGPRPLFMIGQPMDASGFTS
                     LASYFTDRPVITYDPRGLGRSATRRDGRTDAVPEVQAGDVHAIIEALGVGPVDMFASSG
                     GAVTSLALVAAYPDDLVTLVAHEPPLIPLLPDAAAAERARNGFMEAYQAGGQGAGMAAF
                     IAVTSWQGEFTDEFFAQPPADPAAFGMPAEDDGKRDDPLLSDRSVAISSYVPDAKALTA
                     ASTRVLIAVGEETGDTFTGRTAVATAALLGQEATVFPSHHGGFLGGEFGYPGQPEAFSK
                     RLREILDGE"
     aSDomain        complement(16853..17143)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS06315_Abhydrolase_1.1"
                     /evalue="4.10E-10"
                     /label="BN1199_RS06315_Abhydrolase_1.1"
                     /locus_tag="BN1199_RS06315"
                     /protein_end="140"
                     /protein_start="43"
                     /score="31.6"
                     /tool="antismash"
                     /translation="TSLASYFTDRPVITYDPRGLGRSATRRDGRTDAVPEVQAGDVHAI
                     IEALGVGPVDMFASSGGAVTSLALVAAYPDDLVTLVAHEPPLIPLLPDAAAA"
     misc_feature    complement(17260..17280)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.04"
                     /tool="antismash"
     misc_feature    complement(17294..17309)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            17426..17698
                     /locus_tag="BN1199_RS06320"
     CDS             17426..17698
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672872.1"
                     /locus_tag="BN1199_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="WP_042179741.1"
                     /transl_table=11
                     /translation="MTVGGLISALIVGLIIGALGRLVVPGKQSIPIWLTIVIGVVAALI
                     GTFVANALGVGDTSGIDWIEILIQVLIAAAGVSVVAGIYGRRQVR"
     gene            complement(17752..18354)
                     /locus_tag="BN1199_RS06325"
     CDS             complement(17752..18354)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="BN1199_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_083466181.1"
                     /transl_table=11
                     /translation="MPRMRREEAKEHNRQRIVDAARGHFLREGFHNASLGRIADTAGFS
                     TGVVYSQFGGKAELAMTVLCTLYAEETDRVLGLVTGQPEQTVEDWLAAVGDWAEVRVGD
                     PDWGRFELELNGALSGQDKLKDLMSVLYGQIRERVVDLLSARSRDLELHGRSPEAVATL
                     LLAVILGVGLQRTADPAVPARLVTEALRALLLPDRAE"
     misc_feature    18361..18378
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.54"
                     /tool="antismash"
     gene            18456..19319
                     /locus_tag="BN1199_RS06330"
     CDS             18456..19319
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-171). E-value: 3.5e-14. Score:
                     45.0. Matches aSDomain:
                     nrpspksdomains_BN1199_RS06330_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020663346.1"
                     /locus_tag="BN1199_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_042179745.1"
                     /sec_met_domain="adh_short (E-value: 5.7e-34, bitscore:
                     114.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVFHDKVCVITGAASGMGRSLSVELAHRGARLAISDVNTLGLAE
                     TERQCKTVGAQVKADALDVAERGAVLEYADTVAEHYGAVHYVFNNAGIATASTFEQSSF
                     KDLEKIMDVDYWGVVNGTKAFLPHLIASGGHVVNTSSIFGLFSMPGFTAYNSAKFAVRG
                     FTEALRMEMLAAGSPVAVTCVHPGGIKTDIARNMTQPSTGEVADFARLFDRITITSAET
                     AARIILRGVARRSPKVLVGPDAKVLDLLVRLTGAGYQRLTTFVATRVLRGTKVLPHVLP
                     GAHRDA"
     aSDomain        18477..18968
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1199_RS06330_PKS_KR.1"
                     /evalue="3.50E-14"
                     /label="BN1199_RS06330_PKS_KR.1"
                     /locus_tag="BN1199_RS06330"
                     /protein_end="171"
                     /protein_start="7"
                     /score="45.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VCVITGAASGMGRSLSVELAHRGARLAISDVNTLGLAETERQCKT
                     VGAQVKADALDVAERGAVLEYADTVAEHYGAVHYVFNNAGIATASTFEQSSFKDLEKIM
                     DVDYWGVVNGTKAFLPHLIASGGHVVNTSSIFGLFSMPGFTAYNSAKFAVRGFTEALRM
                     E"
     CDS_motif       18480..18551
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN1199_RS06330_0001"
                     /evalue="1.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BN1199_RS06330"
                     /protein_end="32"
                     /protein_start="8"
                     /score="17.7"
                     /tool="antismash"
                     /translation="CVITGAASGMGRSLSVELAHRGAR"
     gene            19400..20041
                     /locus_tag="BN1199_RS06335"
     CDS             19400..20041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669064.1"
                     /locus_tag="BN1199_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA alkylation repair protein"
                     /protein_id="WP_042181892.1"
                     /transl_table=11
                     /translation="MAELASLEDPRAREVNEKHGDDHGVNLGKLRALAKRLKTQHELAR
                     HLWETADTAAKLLATLICRPKAFERAELDAMVREARTPKVHDWLVNYVVKKNPHVEDLR
                     LAWSADPDPVVASAGWALTVERVAKRPEGLDLAGLLDVIEAEMKDAPDRLQWAMNHCLT
                     QIGIKHPEHRARAIDIGERLEVLKDYPTAPNCTSPFAPIWITEMVRRQAG"
     gene            20386..20859
                     /locus_tag="BN1199_RS06340"
     CDS             20386..20859
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1199_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_042179747.1"
                     /transl_table=11
                     /translation="MTKLRSRLLILLLSLSLGLIVATPAHAEKLGPRPNWGACGTSTSE
                     QKMVYDFGGITLKCGNAGWGFRHIKDRHLNEFQGLARAGGLNWSDLVHWAIHFNTKDPD
                     HVIVEEGDGCRDRMLFLHDRNGRLVWQQRFKMIYSAMDGRVITTYPSSAICKR"
     misc_feature    complement(20951..20965)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    complement(20994..21008)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.29"
                     /tool="antismash"
ORIGIN
        1 atcggggtga cctgcaccag ttgggtgttg aggttggcca gcgtggcgaa gttctcggtg
       61 aagaggaggt tgtagaccac caggatgccc agcgccgcgt agacgccgta gtcgcgcagt
      121 cgccgcacag tgggcgcggc gaccggggtg acggttgcct cagccatcgc cctcaccgcc
      181 gtccgcgagc gccgcgatca gcttccgctc ggtcacgtcc gcgcctctca gttcggcgac
      241 cacccggcct tccctgagca cgacgaccga gtccgagcct tcgacgacct cctcgaactc
      301 cgaggagatc agcacgaccc cgagccccgc cgcggccagt tccgccacca gcgcctggac
      361 ctcggccttg gcgccgacgt cgatccccct ggtcggctcg tcgagcagca gcaccttcgg
      421 ctcccggcag agcagcctgg ccagcagcac cttctgctgg ttgccgccgg acagctcgcc
      481 caccttctgg tcggggccgg atgccttgat ccgcaggcgt ttcatgaacg tgtccacaat
      541 ggcgtcctgg cgtccgcggg acaccaggcc cgccgcggac agccggggca acgccgcgag
      601 cacgatgttc tcccgcaccg acaggtccgg caggatcccg tcggccttgc ggtcctccgg
      661 cagcatcacg acacctgcgc gcatcgccgc agcgaccgaa ccggaccgga ccggcttgcc
      721 cgcgaccgtc accgtgccct cgtcgacggg cagtgagccc gcgatcgcgc gcactgtttc
      781 actgcgtccg gcgccgagca acccgccgag gcccacgatc gcgcccggcc gcacggtcac
      841 gtccacgccg tgcaaccggt gctgactggt caggcccctg gccgcgagca ccggtgtctc
      901 caccgtctcg gtgggcgcgg agtcgaactt ggtcgtgcct tccctgcgga tctgctcgag
      961 gtcacggccg agcatgagcg cgaccagctg cagccgcggc aactcggcca gcggaccact
     1021 gtggactttg cggccgtcac gcagaaccgt gacggcgtcg cagatccggt agagctcgtc
     1081 gagccggtgg ctgacgtaca acaccgcggc cccgctcgcg cgcacttgct cgacgatctt
     1141 gaacagggtg tcgacctcgc gcggctccag cgacgacgtc ggctcgtcga ggatcaccac
     1201 gcgggcgtcg gtggcggccg ctctcgcgac cgccaccatc tgccgcaccc ccgcgcccag
     1261 ggtccgcagt ggcctcgtga cgtccacgtc gatgccgtag gaccgcaaca gcttcgccgc
     1321 ggccgtgttc atcgcccggt agtccagcag cccgaagcgg gtgcgtggct cacggccgag
     1381 gaacaggttg ctggccaccg acatcaacgg caccaggttg atctcctggt acaccgtgct
     1441 gatcccggcc gcctgcgcgt ccagcggtcg gccgaaacgc acgggctcgc cctggtggac
     1501 cagttcgccg ctgtccggcg gatggactcc cgtcagcacc ttgatcagcg tcgacttgcc
     1561 cgcgccgttc tcgccgacca gggcgtgcac ctcaccggcg agcaacgtga ggtccacttc
     1621 ggacaacgcg accacaccgg ggaaccgctt gcccacagcg cgggcgtcga gcacgacctc
     1681 gctcggcatc agtacgcgtt gcccagttcg gcggcggcgt tgtccttgtt gtacagcttg
     1741 tcgctgatca ccacgttctg ctggaccggt ttgccaccga agtacgactc cagcgtctgg
     1801 aacgccaacg ggccgaaccg cgggttggac tcgacgaccg cggacagctc gccgtcgacc
     1861 accttctgca cggcgttgcg ggttccgtcg atcgacacca cccggatgtc cgtcccggcc
     1921 ttcttgttgg ccccgcgcaa cgcgaccagc gcgccgagcg ccatctcgtc gttctccgcg
     1981 tagacgccgt tgatgtccgg ctgggcctgg atgatctgct ccatcacctg ctggcccttc
     2041 tccctggcga actcgccggt ctgctgggcc accacctgga tctccggcgc ggacgccttg
     2101 agttcgtcga cgaacccggc ggtgcggtcg gtcgtcacgt tgttgccgga cgcgccgagc
     2161 aggatcgcga ccttgccctt gttgttgagg gccttggcca tctccttggc ggcccgcttg
     2221 ccctgctcga cgaagttgga gccgaggaag gccacgtagt ccttgcaggg cgaggagttc
     2281 accttgcggt cgatggtcag caccgggatg ttcctggcac gcgcggccga cagcgccggt
     2341 tcgaggccgt cggagttcag cggcgccacg atcagcgcct gcgccccctt gttgatcatg
     2401 tcctggatgt cggagatctg cttgctcagc tgcgaattgg cgttggtggt gagcaactgc
     2461 ctgacaccga ccttggcggc ctcgtccttg atcgactggg tttcggcgat ccggaacggg
     2521 ttggcctcct tctccgactg ggagaaaccg acgacggcgt tcttcaggtc caccttgtcg
     2581 ccaccgtact gctgcagcgt gcaggtggga ccgtccgtcg cgggcgccac cggcgcctgc
     2641 gcgccgcccg tgccctgcgc gggcagggtc ggcgtttcct cggacttggc gcagccggag
     2701 agaaccagcg cgacgccgca caggctcgca ccaaggatcc ggcctaagtg gacgggacgg
     2761 gactgggtgg cggcggccat gggctgactc ctcgtcgaga caggcgaact cgctcggcga
     2821 gcacgttaca tcgttggtac aacgttgtaa atacgctcga tcttgatacc ctcaccgacg
     2881 tggcaacgct caaggacgtg gctgaactgg ccggggtgtc cgtcaaaacg gtgtccaacg
     2941 tcgtgaacgg gtactccttc gtcaagccgg agaacgagcg cagagtccgc gaggcgttgg
     3001 ccgcgaccgg ctacaagccc aacgtcggcg cccgcaacct gcgccgcggc cggacgggct
     3061 tcatcgcgct gatggtcccg gagctgagca tcccgtactt cggggagctc gcgggcgggg
     3121 tgatcaccgc ggcgcacacg cacgactgga gcgtgctgat cgagcagacc cacggcctgc
     3181 gcgatcccga ggtctccacg ctggcctcac tggggccgca catggtcgac ggcgcgatca
     3241 tcagcccgga ggcgctgcac acgcaggact tcacccgcaa tcccaccgac gtgccgatgg
     3301 tgctgctcgg cgagcactca ctggacgtgc cgatcgacca cgtgggcatc gacaacgtgc
     3361 aggcggcccg gatcgcggtc cggcacctgg tcgacctcgg ccggaccagg atcgccgtcg
     3421 tcggccagaa ccccaaccga ggcaccgcgg ctcaacggct cgcgggctac cactccgcgc
     3481 tcgccgacgc cgggctgccc agcccacccg actacatcgc accggccgcg cggtaccacc
     3541 accgcgacgg cgccgaggcc atggcacgcc tgctggcact acccgaaccg ccggacgccg
     3601 tgttctgctt caacgacatg ctcgcgcacg gtgccgtccg cgccgccgcc gaacgcggct
     3661 accaggtgcc aggggacatc gccgtggtcg gcttcgacaa caccgagcac agcgcgtaca
     3721 gcctgccctc gctgacgacc atcgccccgg acaaggccgc gctggccaag gccgccgtgg
     3781 atctcgtaca cgaacgggcg agcggcgacg tcagtcccgt gcgggacgtg cagatcccct
     3841 ttacgctcca ggtccgtgaa agcaccgcgg gttagccctg gtaatgtggc cacagcggag
     3901 gggagtaccc acccggtcga gattcgtcaa tacggcgccc ccagtggtga cccggtctcg
     3961 gcgccacaga gcgttgacgc gaacagggtc gacgtgagca gtgtggttgg ggagacctcc
     4021 ggttcactcg aagaaccgga agggattcgc atgcgttcca cgaagcggct gctgacaggt
     4081 gtcctcggcg gcggtgcgtt ggtcatcgcg ctgaccggct gtgacgcggt caagggtgcc
     4141 cagcaggctg cggaaggtgc cagcaacgcg gcctccaccg tgcaggtgtg tgccgaggcg
     4201 ctgaagatcg ccgccttcaa cccggacacc gcgaaccccg aggccgccgc ccagggcgcg
     4261 aaggacgcgg gccagaagct gtccgacctg gcgggcaagg ccacgaacac cacggtcaac
     4321 caggcgctca ccgacctctc cacgaccttc aaggagacca cggccaccga cgtggtcaac
     4381 ggctcgacca actggatcaa gaccaaggcc gaccaggtcg ccgccctcac caaggcctgc
     4441 acctcgaccg gcggctgaca cgcgaaaccc cggtgaccgc cgttagcctc accgggtgag
     4501 tttcaacgcc ttcgccaacc acgtacgcaa cccggcgctg cccttcgggc gccgggtggt
     4561 ggcgttgcgt tgttgtgtcc agctctatcg gccgatcggg tatcacgcga ctctcggcta
     4621 cctggcgatc ctggccgggc cgttccagca cgaagaagcg gcgctgctgc gtgcgctcga
     4681 cgcgttgtcc gcgagccgcg ccagctggca cgccgatctt gagcagtacg cccaggtccg
     4741 ccgcgtcgcc aaacggaagg ggcagcgcag tccgcgcccg cgtgacccga accccaacac
     4801 gggcccgcac tactggtacg gcgctcctca gaaggcggcc gcgtacgcgt tgctgacgtg
     4861 gcgcggccag aaccacggtg tggtgagccg gttctcgtcg ctcgtggatt cgtcactggc
     4921 cgcagacgga gcactcacac cagcgcagcg ggacaggctg gacttcgagg tcgacatggt
     4981 gcgacgcagt atccgcgcag gtctgtacag catcgactac gcggcctacg gctacgcgcg
     5041 ggagttgctg gtcgtcgcgc accacctgcg gatcgcggcc gactacagca gctgagcgtg
     5101 cacgctggac gcgtgcacgc ctcgatggtc actagctggt cgtgagcttc cagtccggcc
     5161 ggatgtagtg gcaggtgtag ccgttcgggt agtgctccag gtagtcctgg tgctccggct
     5221 cggcctccca gaagtcaccc agctggctga cctccgtcac caccttgccc ggccacagtc
     5281 ctgaggcctc cacgtccgcg atggtctgct ccgccagctg cttctgctcc tcgtcggcgt
     5341 agaagatcgc cgaccggtag ctgctgccga tgtcgttgcc ctggcggtcg cgggttgtcg
     5401 ggtcgtggat ctggaagaag aactccagta ctcggcggta cgacgtctgc tcggggtcgt
     5461 aggtgatctc gatcgcctcg gcgtggccgt cgtggttccg gtaggtcgcg ttggcgacat
     5521 ggcctcccgt gtagcccact cgcgtggcca ccacacccgg ctggcgccgg atgaggtcct
     5581 gcatgcccca gaagcaacca ccggccagca ccgcaacctt ggtcacgtca acgctcctct
     5641 cgtccgctct cgctctgttc cagcgcatcc gcggcatgtt ttgttccggg catgacatac
     5701 gcgaacacgg cggccagcgc gcacagcacg atcggcagca cgaacgccac gttcagcggc
     5761 acccagtgtg tcagcccgcc gaccaacgcc ggtcctgcca gtatgcccac atagccgaga
     5821 cccaccaccc gagccatcag cgtgcccgcc gacctggtgt cgagattccc cgcggccgtg
     5881 aacagctgcg ggacaccacc ggacaggccg aggccgaaca gcatccagcc cgccagcgac
     5941 agcggcaccc actgcgacac ggtcacgacg gtcagcccga ccgtggccag cgcggagccg
     6001 taccggacga tcgcgaccgg cccgatgatc gcggcgaccc ggtcggtggc gaagcggccg
     6061 actgtcatcg cggccgagaa cgacccgaac gcgaacgcgg ccgtactcgc cgacgtgcca
     6121 agcaggtcct tggagtgcag cgcggcccag tccgcggcga caccctcacc cagcatcagc
     6181 gcgaacgcca gcaaccccag cagccacacc agcttgccgc cggtcgccgc cttcccagcc
     6241 ggttcgccct cgttgtcggc ctgttggtgg tcgggttcga gcaggaaccg cgccgtcgcc
     6301 agcgagatga tcacgacaag gacgccgcac gtgctcatcg aaacctcggt cgggacgccc
     6361 gcgccgagca gggcggcgcc gacggtggcg gccagcgcgc cgccgacgga ccacatcgcg
     6421 tggaacgccg ccatgatggg ccggggatag gtccgttcga ccacgaccgc ctgggcgttc
     6481 atgccgacgt cgatggtgcc gttggcgaag ccgaacgcga ccagcgacag cccgagcgtc
     6541 catcacgagt ccgccagtcc gggcccgaac agcgcgcagc ccatcaaaac accggccgcg
     6601 ggcacgagtt tgcgctgacc gatgcgatcg gcgacagcgc caccgacctg catcccgacg
     6661 aacgccgcac cgccgagcag cagcaacagc aggccgaggg tgctgtgact gatcccggtc
     6721 gcgcgttcga cgttcgggat gtgcacgacc cacaggccga cggagaaccc gttcagcgtg
     6781 aagtagatcc aggtggcgac ccgggcggcg cgggcaggcg gcgcggcgag ctgtgtcatc
     6841 ggcaggcact cctcacaccc gtgatcatcg caggttgggg catgatgttg cggtgaccgg
     6901 ctaccccaag ggacggcagc gccgggagga catcaccacg gccgcgatcg aggtctaccg
     6961 cgagacgggc taccacggct cgtccctgcg cgaggtggcc aaacgggccg ggatcacgca
     7021 cgccggtctc ctttactact ttcccaccaa ggaagcgctg ctcgccgcgg tgctggagcg
     7081 ccgcgacgcc gaggacgccg aacgggagaa gctcgacatc ccgccgggca tcgacctgtt
     7141 gcgacacctg atcgcactgg ccgagtacaa cgtggcccac cgcggcatcg tggaggtgta
     7201 cgcccgcctg gccgccgaag ccatcgcacc cgaccacccg gcgcacgagt acttcatccg
     7261 gcactaccgg atcgcccgcg acggcgccgt ggccacattc gccgcgctgg ccgagagcgg
     7321 tcagctgcgc gacggcgtgg atccgcgtgc ggccgccgcc gcgttcatcg cgatggaaga
     7381 cggcctgcag gtgcagtggc tgaccactcc ggacgaggtc gacctcgtcg ggtcgctgcg
     7441 gttcttcctg cagaacctgc tgacggtccc gctggactag aacgtccgct cgtacgggtc
     7501 ccagtccacg ggcaaggcgg gcgggatgtc ggcgctgctc tccaccacga ccgtgcgacc
     7561 gctggagatc gactcgtcga tggccagcat ggtgtcgagc acgtggtagg ccagcgcacc
     7621 cgaggcccgc tcgggcacac cggtcctgat cgcccgcgcc agttcgagca caccggtccc
     7681 ccgcgtggcc gtgtgtcctt gcgcctcaac ctcttgcggt tgttcccggc ccggcaggtg
     7741 cagcgtggtc ggcccctcga agtagttggg atcgggcagc acggcgacac cgcccgttcc
     7801 ggtcacttcc agcaagcccg tccggagcag cgccgagtcg aagctcagca cgatctgcgc
     7861 tgagcctccc ctggcgaact ccaccagcgc ggtgaccgag gtcggcaccg tcacggcgaa
     7921 ctccgtcccg gcacgcggcc cgctgccgat cacccgcgtc ggccgggcct gcccaccggc
     7981 gccggtgacc ctggcgatcg gcccgagcag ggtgaccagc gaactcaggt agtagggacc
     8041 catgtccagc agcggccctc cccctgcctg gtacaggaac tccggcgcgg ggtgccagct
     8101 ttccgggcct ggcgtctgga acaacgccag cacagtgcgc ggttcgccga tccgaccgtc
     8161 gtcgatggcg cgacgcgcgg tctgcagccc cgcgcccagc agagtgtcgg gcgcgcacgc
     8221 gacccgcaag cccttctccg ccgcgcggtc gagcagtttc cggcccgact ggcggtccag
     8281 tgccagcggt ttctccgacc agacgtgctt gcccgcgtcc agcgcggcca ggcccacctc
     8341 ggcgtgcgcg gcggggatcg tcaggttgac gacgagttcc acctgcgggt cggtcagcag
     8401 gtcggcgacc gtgcccgcgc ggggaacgcc gtgtttgtcc gcctgtgcct gggcacgggc
     8461 ggtgtccaga tccgcgacgc gcaccacgtt cacgtcggga aagctcgtca ggttggtcag
     8521 gtacacgtcg ctgatgacac ccgcgccgat gacgccgata cccaggctca tcccgcacgc
     8581 ccctgcaggt aggcgaaact ggccgcgatg ccgtcgaaaa tgtcgccgtc gtagcggtcg
     8641 aactcgacca cgcgcagcgc cttgggcgcc gcggcgagga catcggccac cgccagtcga
     8701 ccttgccccg ccgggacctg gcccgatgcg tcggtggcca gcccaccgtc cttgacgtgg
     8761 atggcgtgca cccggtcgcc gagtcgccgc agcagcgcgg gcgcgtcctc gccgcccgcc
     8821 accgcccagt acgtgtcgac ttccagcacc agttccggat ccagccggtc ggcgaacacc
     8881 tcgaacgcgc tgcggccgtc gatccgggat tccagctccc accaatggtt gtggtaaccg
     8941 acggtgacgc cgtactcgtg cgcgatcgcc gccgccgcgt tcagcgcctt cgcggtggcc
     9001 gcaatgtcgt cgacgccccg ccacttctcg gcgggcacga acgggtcgat caccacgctc
     9061 acaccgcact cggcggccac ctcgaacacc gctcgctggt cggcgtcgat cagctgtgcg
     9121 tgcgcggtcg gcgcggtgag accgctctcc cgcaggccgg tccgcagcac agcggcgttc
     9181 tcgacgaggc cgtacggctc cacctgggtg aacccgatcg cggcgagccg ctggaggact
     9241 tcgccgggac gctcggcgaa ctcgtcccgc acggagtaca gctgaacgga cacggtagtc
     9301 actgcggccc cctggcatcg gcgacgatgg aagcgctctc acatttttct accacgtggt
     9361 aagtattcat gccagagggt agtggacgcc gtgcccggac cggaagtggc gattcagagc
     9421 acgagcgtgg gtgtggcgac agagcagaca gatctgttgc ggcagaggga gatctgggcc
     9481 agcccccggt gcacggacgc atacgtgaac cgcccggtgg cgctggcgga cacctcgagg
     9541 acaccggctg ccgtccgcag ccggacgcgg caggcggcgg cgggcgcgac ccagccgtca
     9601 acccggacgg tgacgtcggc gtcctcggtg atcgcgatca ggacggtctt tcccgcgccc
     9661 tcgaaggtga gcatccgcga ccggtcgttg cggtggcggg acacgggacg caggaactcc
     9721 gcgtccgggc tttcatggtc gagcgcgaag tcgaccatgg cggccagatc gtcggggacg
     9781 gggtcgaccg cacgctcctg tgtgacgaga cggtcgatcg ccgggtccgc tggcgtgtag
     9841 ttcaccttca cagccccggt atcggtcacc cgcgcggcgg cgttccgggt agcggacccg
     9901 attgccgcgg cgggcaacac attcatacga atgccgacgt ggcgccacag cgtccctgcc
     9961 cgccatgaca ccacgtcggc gtcagttcat ccggtagtgg tcattcggta ccggatgtcg
    10021 gttcttgttc ctgttgtccg gacgacttgt accgcggatt ggtggcgtgc cactcgaaac
    10081 ccccgcccat ccaggcgcgc agcccgcgca ggaaccgttg cagttccagc gagggaatcg
    10141 cctgcagggc gcggtgcccg gcctcgaagt ccttgacgat ggtgttgtgc aggtcgactg
    10201 tgacctcggt cgcctcctgg atcgagcagg cccggtccgc cgcgatctgc aggaccatgt
    10261 tgcacacggg agtttcgtcc gccgcgtcct tttccaccga gtacaggtcg ttgacgagca
    10321 ctgtcgccgt gcccgcccgg aacgccgcct cccggacacg ggggtcgtag tagaccgacg
    10381 cgggcacctc gtagccgccg acgacgtcga tcagcgtcat cgacgtgtag aaactgtcgt
    10441 gttggcgtgc ggccaggtac tcccacgccg gtgggtactc gctggtgtat cgccaagcgg
    10501 cataagcgtt ccagctgacg aacatggcga atgtggagta gttgacccgc tgcacctgcg
    10561 cggccgagcc gagttgggcg atgtgctcga caccggagcg cagtgacacc aacaccgggt
    10621 ccgagcccag tgccgactcc agctcaccgg tgaactcccc ggccgggggc ggcgggtcca
    10681 tcgccgccat ggccagggac agccgtggcg gcaacgctgt cggcgtcgcg cccatctcgc
    10741 tgtcgtcggc gtacaggtcg tccgccgccc accaggcggc gttcatctgc gccgcgatca
    10801 gcaggtgatc cgggtcgtcg gagtccgggt gcgccagcat cgccagtttg ccgaacccgg
    10861 cccggcccag cagttcgagg ttctcgcctt cgaacccgca ctcccccgcc cagatcacca
    10921 gcctcctgtt cacctcctcg gccaacggtt cgttcacacg ctccacaacg ggtacgtaca
    10981 acggcggcgc ggtcgcatca ccccactctc tctccacgta ggctggatca tgggaaagcc
    11041 gggacatcac gcgtgcggcg gatgtcccca gccccgacgg tccgaacagg atgtccgtca
    11101 tctggttgtc cccagttgtc agattcggtc ggccgcgatc agcaggtagt ggaagctgcc
    11161 ttccttgtac gcggtcagga acgggtcctc gatcccggtc gccaccgagg actgcgcccg
    11221 cagttcccag tacgggatcg tcgccgcggt caggtcgacc acgttgatcg ggacgaaccc
    11281 gttgtcggac aacgccttga agtactcgct gcgggggtgg atgttgcaga tgtagtgctg
    11341 gtcgatctgg ctgaccgcac gggagcgccc accggtcacg tcgttgtagc acccggtgat
    11401 gcacacgtac cggccgccgt actccagcaa ccgcgcgaat tccctgaaca ggtcgtgcag
    11461 gtccacgtac atcgtggtct cgttggacca gatgccccgc atcgaaccgg tgtcgaaccc
    11521 cgtgtcgagc atgttgcgga agtggaaccg cacgcgatcg ttcacattcc gttgctgcgc
    11581 ttgatcattg gcgaacgcga cctgctgctc ggagatgctc acgccgtcga cgtggcagcc
    11641 gaagcggtgg ttggccatga tgctggtgcc gccccggccg gagcccgcgt ccatcagccg
    11701 gtccgactgg ccgatggatc cgaggtggtc gagcagcaca tcggcctgcg cggtctccag
    11761 ccggtgcatc tccttgatga ccgcctggtc gcctgcctgc agcaccgacg ggtcgtagtc
    11821 gccgatgccg tagtggtggt ggtagagccc gtcgacgtcg cccagtctga gattgaccgg
    11881 atccttctcg ttgttccagt acgcggcgat ggaacgctga tagtcgctgc gcagcacggg
    11941 tccggtggtg gactggacag tggccatccg gtgactccat ttcgaggctc ggggttctcg
    12001 ccttcctcac cgagcctggc agccgcgccg cgccgccggg atccgccagc cggggcccgg
    12061 cggcgcacta acgggtggtt cactgtagac cgcccgtagc gcactgccgc gcactgtcca
    12121 caagtgatct tcgcatcccg gcgttttccg ttcgccgcac ggcgaacgtt aacctgatcg
    12181 gggtagctca gccctcgacg gcgctcttga tgtgcgccag cgtcgcggcc atgttgcgtt
    12241 cgaactccct cagtcggacg aacacgatct tctgttcctt gtccggcatc cggtcgatcg
    12301 cggccgagag gcccgaccgg ccggggccca gctgcatcca ctgcgccaac tcggtgccgc
    12361 cgtcctgggg ccgcaggtga aaacgccaga cagcggccgg ttcggcgacg tcaccgaccg
    12421 cccagccgaa ggtccggccc ggctcgaagt cgaccacctc cgacgtggtc gaccactcgc
    12481 cgaacgactc gtgcctgctg tgcccgacga acttgtggcc gaggccgggc ccggagacgt
    12541 cgtccagcca ccgcaccgac tgcagttccg tgctcatgtc gggcatccgc ccgacatcgg
    12601 acacgatcgc ccacacccgg tcgggcgacg cgtcgatcca cgtccgcacc tcgacggtcg
    12661 gcttgtccgc gtaccgcgcg ccggtccact ccattgccgc gtcacccctt cgtgttcgcc
    12721 aaccaccggt tcttctcatg tttcgggaaa ccgccgccgg gcctccggca gggccttgag
    12781 ccgttcggga tagccgggcc cgagtcgcat cgtcacgtca tcggatgtca ggtgttcgcc
    12841 gcaggccgaa cagaccacgt ccgcgtgcgc gtcctgcccg catccggtgt gccgcatggt
    12901 caccggtgga ccatccacac tggacagcca gcggtcgccc cagcgggtca tcgcgatcag
    12961 cacgccgaag aagtccctgc ccttctcggt gagcacgtag tcgtggcgcg tcggcttgtc
    13021 ctggtacggc tgtttgtcca gcaggccttc ggccaccagc cgggtcagcc ggtcggtgag
    13081 ggtgttgcgg gcgatgccga gcccgtgctg gaagtcgtcg aaccggcgga tgccgtagaa
    13141 cgcctcgcgc agcaccaacg gcgtccacca gtcccccaac aggtccatgg tccgcgcgat
    13201 cgaacacggc caccggccca acgaactgcg cttcacccga tctccctgac catctcgatc
    13261 gccgtggcga gcgtggccag ccgttcgtcg agcgtccggc ccgccggata cagccggacc
    13321 gtgtccacgc ccgcgtcacg ccacacccgc agccggtcgc ggaccatctg gtcggtgccg
    13381 atcagggtgg tgcccagcac catctcgtca gtgaccaact ccgcggcacc gtcccggtca
    13441 ccggcctgcc agcgctcgcg gacctcggcg gccacgtccg cccagccctg cctgctgtag
    13501 gcctggttgt agaagttcgt cgacgcggag cccattccgc cgaggctgaa cgcgagttcc
    13561 ttgcggcgat cggcgaccat cgcccgcagc gcgtcctcgt cgggcgcgaa cgcgacctcc
    13621 gcgccctggc agatgtccag gtccgccctg gtgcggccgc tggcggcgat gccgtggtcg
    13681 atgtgccgga agtacgcctg ctcggcgcct tccggcacga agctggtgcc gagccagccg
    13741 tcggcgaccc gcccggtcaa tcggagcatc gcgggcgaca gcgtcgccag gtacaccggg
    13801 atgcggtgcg ccggacgcgt ggacagccgc atcggcttgc tgtccccgcc gggcagggga
    13861 atgtggaacg cctcgccggt gtacgcgatc ttgccgccgt ccagcacctg ccggatgatc
    13921 tcgaccgtct cgcgcatccg gaccagtggc ttggcgaacg gcacgccgtg cagcccctcg
    13981 atcacctgtg gcccagaggc tcccaggccg agcaggaacc gcccgtccga caggttcgac
    14041 agcgtgatcg cggtctgcgc gatcgccacc ggggtgcgtg taccgagttg gaagatcccg
    14101 gagccgagca ggatccgctc ggtccgcgcg gcgaggtagc cgaggaccga cgggccgtcg
    14161 gatccccacg cctcggccac gaaacacacg tcgaggccga gccgctcggc ctcgtcgacg
    14221 aagtccgcct gcgtgtgcca gtcgcccgag acttcgactg tcgttgcggt gcgcatgcca
    14281 gtcggcctcc tcgtcacgcc atctaccagc atagttgcgt agatagactc actgcgtcaa
    14341 gagtggcgca acctcaccgg agggtggaac gtctagttcg acactctcaa caacgctcgt
    14401 ccacgagggg gaactcgtat ggcacaccca cctggccaca ccagacgtcc agcggtcggc
    14461 gcccacaagc tcccggcatg ggccaaggcg gcggctcggc cacgcgcccg caaccgtgcc
    14521 gcggcgctgc ccaccaccgg cagctacgtc acgatcgtgg cgcactccga cgacgaactg
    14581 ctgttcatca acccggatct gcaacccgcg atcgacgcgg gccttccggt ccgcacgatc
    14641 tacatcaccg ccgaccagaa caacgggtac ccggcaggcg gcctgacccg ggaagacctc
    14701 gccgcccaac tgcacgaggg caccaggaac ggttacgcgg cgctgacagg ccagccgaga
    14761 gactggacga tcgacacgat cgtcgtagcc gaccggatca tcgaacgcaa cacgctcgac
    14821 ggcgcgccgc acgtccaact gctctggatc aacctgcccg acggtggcga cgaactgcat
    14881 tccgaggcgt tgatgaacct gtggaacgac ccgaacttcg tttcaccgac gatcgtgccc
    14941 accggcggcc cggtgaccga cgtccaggag tacacgggcg agcagttgca caacgtcctg
    15001 gtggaactgc tggcgctcta ccagccgacc acgatccgga tccaggaccc ggcgccggac
    15061 gggcgctacg gccccgaaca catcgaccac atcgctgcct cgtaccacgc tcattacgcg
    15121 gtgcgcacgt acgaggggcc ggacgcgacc gggcagtgcc tgctggtgcg ctaccgctgc
    15181 tacaacaccg acctgtcgcc ggtgaacgtc ttcgccccgc tgtacacgcc gaaagccgcc
    15241 gcgtacggcg agtacaagaa gctcgacccg ttgaccggca acgggttcga cgcacaactg
    15301 gaacgcaact accagcggtt cccggtgacc gagccgttcg tgatcaagga cggtaccggg
    15361 gcgttgcacg ccgtcatcgc gggcggcgac aacgtgatcg cgtggcggct caacacgggc
    15421 ggcgcgacct ggtcggcggc gaccaccctg gtctccggtc agttcgcgcc cggtgtcgcg
    15481 atggaactca acgccgacgg caccgtccag ctggctgtgc tcgacctgga ctcgtccacg
    15541 atcatgacca ctcggcagac cgcgcccggc gccggattcg gcccgtggac cagcatcggc
    15601 gcccccgacg ggatcctcgg cgtgcccgcg ttcgggcgca actccgacaa ctgccttgag
    15661 ctgtacgtgc tcaacgaggc cggtggcctc agcaacgcct accaggagac gccgaacggc
    15721 acggtcttca agggatggga cgacgtctcc ggcgggccgg acatcctcgg tcagccgacg
    15781 gtgtggaaca gcgccgacaa cacactgaac atcttcgccg acagcaacgg aaagatccgg
    15841 cactggaaac agccgcccgg cggcaccacg accgtcaacg cgggcttccc cgcagtggag
    15901 acggtgggca cgccgagccc agtggtcaac acgaccggcc aggggatcct gatcatccgt
    15961 gagcacggcg acgggaccat cggccggagc gtcgagcaga cggctgccgg gacgtggtcc
    16021 ggcctggcgc acatcggcgg gcagggtggt ttcggcccga ccttcggtgt ccggaccagc
    16081 ggcacgaccc cgcgggtgtt cgcgttcgcg cgcaacgacg actacggcat cagcctgaac
    16141 cggcagaagg ccaacgggac gttcgacccc aacgcgtggg aggacctcgg cgggtactgc
    16201 gagatcggac ccgccgctgt cctggacaac gccgggctgg tgcggttgct cgtcgtcggc
    16261 ggggactgcc ggttgtacga acgccgccag accacggcgg gcccgtcggg cgcgttcacc
    16321 acgtggcagg ccgtctgacg gcagcccgga cgtccatgtc ggactgtcat taatggacag
    16381 tccgacatgg acggcgggat cattcgccgt cgaggatttc gcgcagccgc ttcgagaagg
    16441 cctccggctg gccggggtag ccgaactcac cgccgaggaa gccgccgtgg tggctcggga
    16501 acacggtggc ctcctgcccg agcagggcag cggtggccac ggcggtacgt ccggtgaagg
    16561 tgtcgccggt ctcctcgccc accgcgatca ggacacgagt ggaggcggcg gtcaacgcct
    16621 tcgcgtcggg gacgtaactc gagatggcca cggacctgtc ggatagcagg gggtcgtccc
    16681 gcttgccgtc gtcctccgct ggcatcccga acgcggcggg atcggccggg ggctgagcga
    16741 agaactcgtc ggtgaactcg ccctgccacg aggtcactgc gatgaaggcg gccatgcccg
    16801 caccctgccc acctgcctgg taggcctcca tgaagccgtt gcgggcgcgt tcggcggcag
    16861 cggcgtccgg aagcagtggg atgagcggcg gctcgtgcgc caccagcgtg accaggtcgt
    16921 ccggataggc cgccaccagt gccagcgagg tcaccgcgcc gccgctgctg gcgaacatgt
    16981 cgaccggccc gacgcccagc gcctcgatga tggcgtgcac gtcccccgcc tggacctcgg
    17041 ggacggcgtc cgtcctgccg tccctgcggg tggcgctgcg gccaaggccg cgcgggtcgt
    17101 acgtgatcac cgggcggtcg gtgaagtacg acgccagcga ggtgaaccca ctggcgtcca
    17161 tcggctgacc gatcatgaac agcggacgag ggccgtccgc tgtcggctga gggccgtgca
    17221 cgtcgtagac gaggtcgacc tcagtggttt cgagcgtgtg cgtagtcacc atgacgttat
    17281 agacggccgg tgtgtcaaaa catcgtcggt acctggccaa tcgatcgagt gatcaacgcc
    17341 gcaaggtgtc ttgaaccgat ctgacggcgg gtacctgcag gtcagtgggg tcacaacccc
    17401 ggaggatcgg cagcgaggag cagtcatgac cgtcggtggc cttatcagcg ccctcatcgt
    17461 gggcctcatc atcggcgcac tgggacgcct ggtcgtcccc ggcaagcagt ccatcccgat
    17521 ctggctgacg atcgtgatcg gtgtcgtcgc ggccctgatc ggcaccttcg tcgcgaacgc
    17581 gctcggcgtc ggcgacacct cgggcatcga ctggatcgag atcctcatcc aggtgctcat
    17641 cgcggccgcg ggcgtgagcg tggtcgcggg catctacgga cgacgacaag tccgctgacc
    17701 cccgtccccc actcggtgcc ctggtgaccg gccggtcacc agggcaccga gctattcggc
    17761 cctgtccggc agcaggagcg ccctgagcgc ttcggtgacc agccgcgcgg gcacggcggg
    17821 gtcggcggtc cgctgcaggc cgacaccgag gatcacggcg agcaggagag tcgcgacggc
    17881 ctccggcgaa cggccgtgca actccaggtc ccgcgaccgg gcggacagca ggtcgacgac
    17941 gcgttcccgg atctggccgt acagcacgga catcaggtcc ttgagtttgt cctgaccgga
    18001 cagcgcgcca ttgagttcga gctcgaacct cccccagtcg ggatcgccga cgcgcacctc
    18061 cgcccagtcg ccgacggcgg cgagccagtc ctcgacggtc tgctccggct gcccggtgac
    18121 caggccgagc acccggtcgg tctcttcggc gtagagcgtg cacagcaccg tcatggccag
    18181 ttctgccttg ccaccgaact gggagtacac cacgcccgtc gagaacccgg ctgtgtcggc
    18241 gatccgtccg agcgacgcgt tgtggaagcc ctcgcgcagg aagtggcccc tggcggcgtc
    18301 gacgatccgc tgccggttgt gttccttggc ctcttcgcgt cgcatgcggg gcatcacgtg
    18361 atgctacgcc cttgtgacaa tcagattatc cagatacggt ctgtatccga aatagcccgt
    18421 gctcgcggcc ttgcgctggc gaaggagctg gtcggatgaa cgtcttccac gacaaggtct
    18481 gcgtgatcac cggagccgcc tccgggatgg gccgcagcct ctccgtcgaa ctggcccacc
    18541 gcggtgcccg gctggcgatc agcgacgtga acaccctcgg cctggccgag accgagcgcc
    18601 agtgcaagac ggtcggcgca caggtgaaag cggacgcgct ggacgtggcc gagcgcggcg
    18661 ccgtgctcga gtacgccgac acggtggccg agcactacgg cgcggtgcac tacgtgttca
    18721 acaacgcggg catcgcgacc gccagcacgt tcgagcagtc gtccttcaag gacctggaaa
    18781 agatcatgga tgtggactac tggggcgtgg tgaacggcac caaggcgttc ctgccgcacc
    18841 tgatcgcctc cggcggccac gtggtgaaca cctccagcat cttcggcctg ttctccatgc
    18901 ccggtttcac cgcgtacaac tcggccaagt tcgccgtgcg cggcttcacc gaggcgctgc
    18961 ggatggagat gctcgccgca ggcagcccgg tcgccgtgac gtgcgtgcac cccggcggga
    19021 tcaagaccga catcgcccgc aacatgaccc agccgtccac cggcgaggtc gccgacttcg
    19081 cgcggctgtt cgaccggatc accatcacca gcgccgaaac cgcggccagg atcatcctgc
    19141 gcggcgtggc ccgccgcagc ccgaaggtgc tcgtcggccc ggacgccaaa gtgctggatc
    19201 ttctggtccg cctgaccggc gcgggctacc agcggctgac caccttcgtg gcgacccgcg
    19261 tgctgcgcgg caccaaagtc ctgccccacg tcctgccggg agcacaccgc gacgcgtgac
    19321 ccagcgcctc cccgtaggct gatcgcctcc gaatggtgga cagggggctg acgtggccga
    19381 gacggctgtg gccgaggtga tggccgaact ggcctcactc gaggacccac gcgcacgcga
    19441 agtgaacgag aagcacggcg acgatcacgg cgtgaacctc ggcaagctgc gcgcgctcgc
    19501 gaagcgtctg aagacacagc acgaactcgc tcggcacctg tgggagacgg ctgacaccgc
    19561 ggcgaaactg ctggccactc tgatctgccg cccgaaggcg ttcgagcgtg ccgagttgga
    19621 tgcgatggtg cgcgaggcgc gtacccccaa ggtgcacgac tggctcgtga actacgtggt
    19681 gaagaagaac ccgcacgtcg aggacctgcg cctggcctgg tccgccgatc cggacccggt
    19741 ggtcgcgagt gccggctggg cgctgacagt cgaacgcgtg gccaagcggc ccgaggggct
    19801 cgacctggcg ggactgctcg acgtcatcga ggcggagatg aaggacgccc cggatcgcct
    19861 gcagtgggcg atgaaccact gtctgaccca gatcgggatc aagcaccccg agcaccgcgc
    19921 ccgcgcgatc gacatcggcg aacgcctgga agtgctcaag gactacccga ccgcaccgaa
    19981 ctgcacgtcg ccgttcgcgc ccatctggat caccgagatg gtccgccgac aggccggcta
    20041 gtccctgggc aggccgaaat agtccgcacc ccgtattgag ttcgacgtcg aactgtcaca
    20101 ccaattggcc cgtggggacc tccttgccca agatcacgcc acactgagat catcttccga
    20161 gatgcactcc aagcgccagc cgttcgtcac ctgatcaggc gaattcttgc ctggcatttg
    20221 ccgtagtgat accgtcgctc caaagcaagg caacatacgc gacgcacagg gggtgcttcg
    20281 gtcgcgttct gacccacgtt gcgcgaaacg cgcgaaagtg gcaatcactc acggaccggc
    20341 gagccggaac acacccttgg tcgaagtctt cccaaggagg tcgaaatgac gaagttgcgc
    20401 agcaggctgc tcattctcct tctctccctc agccttgggc tgattgtggc gacacccgca
    20461 catgcggaga agctgggccc gaggcccaac tggggcgcgt gcggcacgtc gaccagcgaa
    20521 caaaaaatgg tctacgactt cggcggcatc accctgaagt gtggcaacgc aggctggggt
    20581 ttccggcaca tcaaggacag gcacctcaac gagttccaag gcctggcgcg ggcgggtggg
    20641 ctcaactgga gcgacctggt ccactgggcc atccacttca acaccaagga tcctgaccac
    20701 gtcatcgtcg aagagggcga cggatgtcga gatcggatgc tgttcctgca cgaccgcaac
    20761 ggtcgcctgg tatggcagca gcgcttcaag atgatctaca gcgccatgga cggccgcgtg
    20821 atcaccacct accccagcag cgcgatctgc aagcgataac aggcaccgat caggtatcac
    20881 gccgatcagg cgaccaatac ccgccctccg agtccgtcaa cgggaacgat cgccgcgcgg
    20941 aaccacgtag atcgacaaga gaaatccggc cctcagcaga ccgcccgagt cgaatctcaa
    21001 gaagagacaa agacacgtcc gactcgaaga tctcctcaat ccacagcgcg acacgcttcg
    21061 cccgaacccg atcccaagca tcccgcggcg agtgcgcaag a
//
