LOCUS       NZ_JWJJ01000004        25388 bp    DNA     linear   CON 08-FEB-2024
DEFINITION  Paenibacillus polymyxa A18 scaffold00004, whole genome shotgun
            sequence.
ACCESSION   NZ_JWJJ01000004
VERSION     NZ_JWJJ01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polymyxa A18
  ORGANISM  Paenibacillus polymyxa A18
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 366481)
  AUTHORS   Pasari,N., Bashir,Z., Adlakha,N., Gupta,M. and Yazdani,S.S.
  TITLE     Insights into Paenibacillus polymyxa reveals importance of
            carbohydrate binding module in biomass hydrolysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 366481)
  AUTHORS   Pasari,N., Bashir,Z., Adlakha,N., Gupta,M. and Yazdani,S.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2014) Synthetic Biology and Biofuel Group,
            International Centre for Genetic Engineering and Biotechnology,
            Aruna Asaf Ali Marg, New Delhi, Delhi 110067, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. FEB-2013
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 16.5x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/08/2024 01:54:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,088
            CDSs (total)                      :: 4,961
            Genes (coding)                    :: 4,885
            CDSs (with protein)               :: 4,885
            Genes (RNA)                       :: 127
            rRNAs                             :: 12, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 12 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 39 of 76
            Pseudo Genes (incomplete)         :: 41 of 76
            Pseudo Genes (internal stop)      :: 10 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:49:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 282419
            Orig. end                         :: 307807
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JWJJ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25388
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..25388
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25388
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15388](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15388
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    1734..1749
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 24.77"
                     /tool="antismash"
     misc_feature    1820..1838
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     gene            complement(1876..2724)
                     /locus_tag="U707_RS17940"
     CDS             complement(1876..2724)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818607.1"
                     /locus_tag="U707_RS17940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PRD domain-containing protein"
                     /protein_id="WP_016818607.1"
                     /transl_table=11
                     /translation="MIIEKVLNNNVLLTKNDKGKEVIVMGRGISFKKVAGDQVDDHKID
                     KIFMLNENEFTARLTELLNDIPVSHLEVVNEIVTHAAEVLDTELSDNIYLTLTDHIHFA
                     IQREEKGLALKNAMLYEIKRFYKKEFAVGLDALQKIENTLGVKLGEDEAGFIALHMVNA
                     RIDGNEMKATLKMTEIVQHILNIITYHYGIVLDESSFSYSRFLTHLQYFAMRVIRKEVI
                     HSGEEFLYNQVKQTYTEAFACAQKINEYLEKTYDQYLSKDEYVYLTIHIHRVTERNNIS
                     G"
     gene            complement(2958..3929)
                     /locus_tag="U707_RS17945"
     CDS             complement(2958..3929)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431750.1"
                     /locus_tag="U707_RS17945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_017427396.1"
                     /transl_table=11
                     /translation="MSNLDQIAKLAGFSKATVSRVLNQSPHVSQETRAKILKIMQELDY
                     VPNRNAISLSKGQTLQIGIITSTINEIVLAFLDSFVEIAGQYEFQTIIYTSGEDKKKEL
                     QAFEDLKRKRVDALVIISCVNDTDFLSTYCKYGPIVAWQRMEHTDIRSVAMDQYEGYML
                     ALKHLIQKGYTRIANAFGRPSSINTHSRQRAYEQIMSEHNLPVLPHWNYSSIYNIRDGE
                     QVVRNLLQHREEFPEAILCANDYVAVGILCEARRQLLRVPEDLAIVGFDNTELAHTMGI
                     TTVQNPIMAQAENAFFMLSPQLIGRQMELHSLEYSLIERTTT"
     gene            4141..5598
                     /locus_tag="U707_RS17950"
     CDS             4141..5598
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348049.1"
                     /locus_tag="U707_RS17950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="WP_017427397.1"
                     /transl_table=11
                     /translation="MTKTLKGFPKNFLWGGATAANQLEGAFDVDGKGLSSADMIAYVPK
                     SERKNDHAIEISSERLKDILAGKVNARFPKREGVDFYHHYKEDIALFAEMGFKVFRMSI
                     HWSRIFPNGYDAEPNEAGLQFYDNVFDELRKYGIEPLVTLSHYETPLGLTQKYNGWLGR
                     EVVDHYVKYAETVFTRYKDKVKYWLTFNEINVMTMSPFTGGGVVIDRVENKQQAIYQAL
                     HHQFVASALATKRGHEIIPGAQIGCMLARIESYPHTCNPEDILKAQHENQMNLFFTDVH
                     ARGGYPNYMNRYFEENNIVIQTEPGDAEILKNNTVDFISFSYYMTLTVSAGPEGEKAAG
                     NLIGGVKNPYLQSSDWGWQIDPIGLRVTLNTFYDRYQKPLFIVENGLGAYDKVEEDGSV
                     HDTYRIDYLRQHIAQMKEAIADGVDLIGYTSWGPIDLVSMSTSEMSKRYGFIYVDLDDD
                     GNGTLQRSKKDSFNWYKNVIATNGEEL"
     misc_feature    5698..5713
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.74"
                     /tool="antismash"
     misc_feature    complement(5736..5754)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.42"
                     /tool="antismash"
     regulatory      5863..5957
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            6116..7534
                     /locus_tag="U707_RS17955"
     CDS             6116..7534
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1153: Amino acid carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016324662.1"
                     /locus_tag="U707_RS17955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sodium:alanine symporter family protein"
                     /protein_id="WP_038978208.1"
                     /transl_table=11
                     /translation="MNLVHVLETIDSWMWGAPLLILVMGTGLWLTIRLKMLQIIRLPLA
                     LKLIGKAPDEGSGDVSSFGALSTALAATVGTGSIVGVATAIKLGGPGSLFWMLVAAFFG
                     MATKYAEGLLSVKYRVKDRNGQFSGGPMYYIENGLGRRFKPLAMLFAFSGILVALFGIG
                     TFPQVKAIVSSTESSFGVPTVVTAIIISVLTAVVTIGGLKSIAKVSTKIVPFMSGLYIV
                     VCLIVLIKFAGELPHAIALVLQGAFSTTSATGGFAGATIMLAMRSGVARGIFANEAGLG
                     SAPIAAAAAKTKWPAEQGLISMTGVFIDTMIICNLTGFTLLVTGIWSGNDDGGLMTQHA
                     FSSAFPAGAELVTISLILFAFTTILGWNYYGERCVEYLLGVKWIKPYRYLFIVLVAGGA
                     FIKLDAIWLLADIFNAMMAFPNLIALLGLSGIVVAETRTYMNSLYPNKNKGILAGANVG
                     AAIQVEEKGQTVNS"
     gene            complement(7660..8280)
                     /locus_tag="U707_RS26240"
     CDS             complement(7660..8280)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372715.1"
                     /locus_tag="U707_RS26240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_226888823.1"
                     /transl_table=11
                     /translation="MQEKRYKETIRSLSDIKRSIHDFKKQLIFVRACLQEQRTEEGVNH
                     INQTLKNIDSPKLHITTGHLVIDALVNHTFSIANKSGIAFFHQIHINPANISIGSHDLC
                     IVLGNVFDNAIEAVMQLPRKKEHSIHLEIFTDNIALWIYVRNSKSNYLNTAFSTKTYNP
                     PLKKHGYGLLNIQQVIKKYGGYLNTTITDSHFQITIMLPCNNS"
     gene            complement(8679..9434)
                     /locus_tag="U707_RS17965"
     CDS             complement(8679..9434)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818612.1"
                     /locus_tag="U707_RS17965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_231124978.1"
                     /transl_table=11
                     /translation="MVYLFQVAVCDDDPAMHKILQHFFMCMSVSESFDFNLQFFLSGED
                     LIKSYSSQERYPFHIILLDIEMRELSGIETAKLIRLFPDREVQIIFLTNYPEYMLESFE
                     VQAFQYLLKPLTYKLFVEKINKLCHYMRSSVSHFLSVKNKTEHLVLRHSEIIAISKGEN
                     NYIHNELCIATDSHNYFISGTLKAVYEQLKYPFVFIHRSIIVNLVHIRKFSATSVIMSN
                     EQEFPVGRSHAKSLREAYARFIISRFQEG"
     misc_feature    9931..9946
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            10001..11329
                     /locus_tag="U707_RS17970"
     CDS             10001..11329
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372712.1"
                     /locus_tag="U707_RS17970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_017427400.1"
                     /sec_met_domain="PTHR43273 (E-value: 4.6e-41, bitscore:
                     135.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.4e-15, bitscore: 52.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.3e-11, bitscore: 38.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3e-17, bitscore: 57.2,
                     seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKASQYNFIFNDIIENTDKTVLYNSRTGALAVLEPEYYKQFCELT
                     NNGLAINNDTYLKNLIECGYIVEDNMNEKAYVKVNLLKNRFESSNLMLTIAPTMACNFR
                     CVYCFEKDQYHNKTMSEETAQSIVNFVKANASKLDTLNVTWYGGEPLIAMKQIVRISED
                     FLEICKENNIQYTASVITNGYLLNKEKVQTLISCGVNDIQVTVDGPKEVHDLRRPLVSG
                     RGTFDVIMNNLKQIKGMIKIFMRINTDQDNWLNLHEIVGFLKENSLLENVIPYLGLVTP
                     TNGKYEGTKCLTDEMYSKFNLKFMSENDIPISYIYPAPKGNYCSADKYNSFVIDPLGHL
                     YKCWSDIGIIEQCVGNINEDTSVKWNTELLGCYLLYDPTEDEKCSDCKYLPVCLGGCPH
                     NRMADFNICEQYRYNLQEYITECTKVLLAGQLTENKKEVSESC"
     gene            11323..11970
                     /locus_tag="U707_RS17975"
     CDS             11323..11970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818614.1"
                     /locus_tag="U707_RS17975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017427401.1"
                     /transl_table=11
                     /translation="MLMLKKMCIVLCGFLLMGMPLGASSNAASNDVKNINLTAINCNVT
                     VTKTSASDFSYEYNKSLYTVTSTLSGSTIYITVKGKGSANGISDRVNILIPDKSYEKIT
                     VESTKSGVSLPELNTNLDITGVDGSSMSVRVPVGYSKAISYDNTKGSGSLTFSKGASDY
                     TVTVKTTASALSVPAGWPLFRPNLTYNYINGAGKAKINITLENSAFSIAAQK"
     gene            12217..13890
                     /locus_tag="U707_RS17980"
     CDS             12217..13890
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818615.1"
                     /locus_tag="U707_RS17980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_016818615.1"
                     /transl_table=11
                     /translation="MIVLEYLKKYLSKTRKYVFFYIVVTSVLWIIGIIVPYITGIYIDY
                     LVSKSNISIILYFVLLLGIINIVNILIQYLTALFSTKLNNLLLYEICNDIYQKIFKTKL
                     SVFKDKDNAYLVDQINNDSSTVVDFFSNNISNLVLQVITIIISGIIVLKADVLLCVIIF
                     SLIPFYIFTYVVFRKKLYKANLKYKKEANEYYSKKVEQINKLVFIKKNVLFNEMNERLN
                     KAFNSLFRVATSQVKTNYIFSNLNQFILIICYIFVIGIGGHKVVIGQMSIGQFTIINTY
                     LSMIISSTSYLLSLASSYQETKVSIERLNDVMNSENDIYGSTTLEDLEKISIKQLGVKY
                     SEESVFRDFSYDFFKGGIYGICGHNGSGKTTLLNTLIGLYSDLYTGEIAFNNCSIKDID
                     MLDMRRYRISYVEQNPEFLNLPIKEYLKFGITFSKEIASNQDELITAFGLEEIITKANL
                     ENILINENGSNFSGGEKQKLALIRALSKDSFLTILDEPTSALDSKSVSGLIEILTKQKS
                     RRITIVVSHDQRLLAACDHILNIETQEERDDIGFHSYGVL"
     gene            13856..15388
                     /locus_tag="U707_RS17985"
     CDS             13856..15388
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372709.1"
                     /locus_tag="U707_RS17985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_016818616.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.6e-08, bitscore: 29.1, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.3e-48, bitscore:
                     160.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.7e-12, bitscore: 41.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.1e-07, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILDSTVMEFFRNIKKQYGNYSRLFKLFQTKNKSYLYDVGTGKVM
                     ECTEIEYVFLNNLQVYGDIEEVIKTTKVNDDTLTILIDLIHVAQEQHLFQAPPLLSFAL
                     SKDEVLENARSHLEQVTLELTEQCNMACHYCIYHSGNIDFREFGRRHMSWQVAELAIDY
                     TLKNSGKKVAVTFYGGEPLIEFKLLKHCVDYTLKNGADKDLTFSMTTNLTLMTAEIAEY
                     LSTVPNFGVVCSIDGPKEIHDCRRVFKNGEGTYDKAINGLKHLINAYGEKSNSLISLSM
                     VTPRPANDVVMKKIQNFFNSLSWVPKDITKNISYVRHSSDIEKTITEKSSMHCYDNPVG
                     NWTIDLMLNNTSISKNTPFTIDFLHKQFSIIHDRILTETPYPDYCLNGCCSPASRRIYV
                     TVNGDFHLCERIGKSPSVGNVYSGIDESVLIDRYIDDYGKESLSQCSKCWAIRLCSVCY
                     VECYDSDKFNIEKKKIACRRSLDMLEHALISYHTILEHKPHLLEELNHITLV"
     aSDomain        13871..14260
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_U707_RS17985_Other_Sactipeptide_rSAM_
                     RRE.1"
                     /evalue="1.30E-09"
                     /identifier="RREFam021.1"
                     /label="U707_RS17985"
                     /locus_tag="U707_RS17985"
                     /protein_end="135"
                     /protein_start="5"
                     /score="29.1"
                     /tool="antismash"
                     /translation="TVMEFFRNIKKQYGNYSRLFKLFQTKNKSYLYDVGTGKVMECTEI
                     EYVFLNNLQVYGDIEEVIKTTKVNDDTLTILIDLIHVAQEQHLFQAPPLLSFALSKDEV
                     LENARSHLEQVTLELTEQCNMACHYC"
     gene            complement(15934..16761)
                     /locus_tag="U707_RS17990"
     CDS             complement(15934..16761)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372706.1"
                     /locus_tag="U707_RS17990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_016818617.1"
                     /transl_table=11
                     /translation="MMQTRAKSIVLYAGLLVGIILSMFPFYWLIVMATRTTSDIYRFPP
                     QLWLGSHFLDNITRVLQQIDFAGAFLNTLFVASSITLLVLFFDSLAGFAFAKFDFPGKK
                     VLFVILLATMMVPSQLSLVPSFVMMASFGWVGTFKALIIPGMVNAFGIFWIRQYAEESI
                     PKELLDAGRMDGCSFFRLYWNVALPILRPAFAFLGAFTFIGAWNDYLWPLIVLTDERKF
                     TLQIALSQLNGIYNTDYAMVIAGTLLAVLPLIILFLFISRQFISDLAAGAIKD"
     gene            complement(16783..17658)
                     /locus_tag="U707_RS17995"
     CDS             complement(16783..17658)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014277626.1"
                     /locus_tag="U707_RS17995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_016818618.1"
                     /transl_table=11
                     /translation="MLREIWKHRAVYAAISPFYLLFGIFGLFPIGFSLYLAFHKWDGIG
                     DMTYNGWGNFRYLVTDNEFWQAVGNTFVIWVYATIPMLFLALIVAFLLYAPFVKMRTLW
                     RVGFFLPNVTSIVAVAIIFGALFANNFGFLNYLLQLLGLPMIQWLNVPWGIQIAISSMV
                     VWRWMGYNAIIYLAGLQSIPHVLYEAAKIDGATGAQAFFRITIPMLRPVILFTVITSTI
                     GGMQLFTEPQVLVGNDGGAGASGMTIVLYLYRESFINNYFGYGAAVGWGMFLIIALFSI
                     INWKLVQGKK"
     gene            complement(17692..18981)
                     /locus_tag="U707_RS18000"
     CDS             complement(17692..18981)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014277625.1"
                     /locus_tag="U707_RS18000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_026065450.1"
                     /transl_table=11
                     /translation="MKTVQWQWLVLCLAFLTMISGCSGSLSSKGQSSEANLSNSKKITL
                     TLWYWNRSIDDELLVQAEKQFPNIELKTQKIGGDFKAKLKTTLAARSGEPDIVALNDWM
                     VELFPSADRFYDLKELGADRLKDQYLEWKWNQGITPDGKMIAFPMDTGPTALFYRSDLF
                     EQAGLPSDPEQVSASIRTWDDYMAAGEQLRQKFGSHSFLADNIVNVYNQVLAQHTNLYF
                     KPDGSYIGNQSPDIRLGWKTAVDFHRKHLLANADGWTPEWNASVNNGKIASFVGAIWMK
                     QVLTEAAPDTAGKWRVARAPGGDGNLGGSFISILKSSQHPKEAFEVLTWLQSPEHQLEA
                     YHKIGLFPSTPGVYDDPVMETPEPFFGGQATGLIFAASARQVKNSYFGERYPVIHGIVT
                     RRLANVAKQNADPDSLWTETMQRIQRELQR"
     gene            complement(19179..20660)
                     /locus_tag="U707_RS18005"
     CDS             complement(19179..20660)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372703.1"
                     /locus_tag="U707_RS18005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PTS transporter subunit EIIC"
                     /protein_id="WP_016818620.1"
                     /transl_table=11
                     /translation="MLKFLQKIGKSLMLPVATLPAAGILQGLALINYETDIPLGPGVGG
                     FLNHYVTPFLNEGAGAIFGNLALIFSIGVAIGLAGDAVAALSAVIAYLVLTRILAAVPG
                     IFAYIPDDVKLDMGVLGGIFIGGWSAYLFKKYHNIQLPDWLGFFSGKRFVPMITAFTTM
                     ILAILLGMIWSPIQDGIAAFGNWIVGFGGIGSMVFMIANRLLIPLGLHHVLNSIAWFQI
                     GDYTNAAGEVVHGDLTRFFAGDTSAGMFMSGFFPIMMFALPAAALAFIHTAKSEKRKAI
                     ASIFIGSALASFLTGITEPLEFSFMFIAPLLYGVHALLTGLSGLVVYLLDVKLGFSFSA
                     GLIDYLVNMKLSTHPLRMIPIGLVFALIYYFLFRFIILKFNLKTPGREDDVDDTLLFEA
                     NKSIPVGKASASSGTQSSQAGQVLTYLGGSDNIQSIDACITRLRLVVKDDKAVNDQALK
                     QLGASGIIRLGNGTLQVIFGTRSEALKDEIQRLMS"
     gene            20979..21803
                     /locus_tag="U707_RS18010"
     CDS             20979..21803
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688424.1"
                     /locus_tag="U707_RS18010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MIP/aquaporin family protein"
                     /protein_id="WP_016818621.1"
                     /transl_table=11
                     /translation="MSPYAAEFIGTMILIALGGGVCAGVSLKKSFAHASGWIVVGLGWG
                     LAVAIGVYAVGPISGAHLNPAVTLALAFQGSFPWQDVPGYIVAQVLGAMAGAGIVILHY
                     WPHWKETEDTAAKLSVFATGPAIDHPFGNVLSEMIGTFIFVLALLSFGANSFTDGLKPL
                     IVGFLVVSIGLSLGGTTGYAINPARDFGPRLMHYLLPIPGKGASNWKYAWVPIVGPLLG
                     GSFAGPFYQAVFKGSMTPAFWILLGVIVVVLLITFRISRIYKNHKMDHKLTA"
     misc_feature    complement(21008..21023)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.4"
                     /tool="antismash"
     gene            21835..23328
                     /gene="glpK"
                     /locus_tag="U707_RS18015"
     CDS             21835..23328
                     /EC_number="2.7.1.30"
                     /GO_function="GO:0004370 - glycerol kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glpK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818622.1"
                     /locus_tag="U707_RS18015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycerol kinase GlpK"
                     /protein_id="WP_016818622.1"
                     /transl_table=11
                     /translation="MGKYILSLDQGTTSSRAILFNSEGDVVYSAQREFPQYFPHPGWVE
                     QNANEIWSSILGVIASCLSESGVKAKQIAAIGITNQRESVAVWDKNTGLPVYNVLVWQS
                     RQTSDICEELKRQGHEELFHSKTGLLIDPYFSGTKVKWILDHVEGARERAERGDLLFGT
                     IDSWLIWKLSGGKAHVTDYSNAARTLMYNIYELKWDEELLDILGVPKIMLPEVRPSSEV
                     YAHTVDYHFFGQNVPIAGAAGDQQAALFGQACYEKGMIKNTYGTGCFMLMNTGDQPVES
                     KHGLITTIAWGLEEGKVQYALEGSVFVAGSAIQWLRDGLRMFREAKDSEPYAARVSSTE
                     GVYLVPAFVGLGSPYWDSEVRGAMFGLTRGTTKEHFIRATLESLAYQTKDVLTAMEIDS
                     GITVKMLRVDGGAVLNNFLMQFQSDILDATVERPVIHETTALGAACLAGLAIGYWKSTD
                     ELRKRVRVETSFTPTMDEATRDSLYEGWKKAVNATMAYK"
     gene            complement(23413..24453)
                     /locus_tag="U707_RS18020"
     CDS             complement(23413..24453)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688423.1"
                     /locus_tag="U707_RS18020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_016818623.1"
                     /transl_table=11
                     /translation="MNIKTIASMAGVSVATVSKIINNYTDISEETRQRVLKIMEETGYR
                     PSSSAKTLATKKSNLVGVIFAGKLNVDFSHPFFVDIINVFKKQIGLLGYDLLFFSNEKF
                     LDNGEDYLARSKYFSVDGCIIIAGDEVEKSVFDLDASPIPCIGVDIELTGASSCYIMSD
                     NQKISMKVVEHFYMNGYREMGFIGIERPSLVIKEREEAFISSLKRFSLDVRPEWIVYGK
                     DYAAEDGYQIAKAWIEQENLPKAIFAATDLLAFGAIRAFKESGLRVPEDIAVVGCDDIE
                     ACRYTDPPLTTVKQDKQKIGRLAAMVLFDLMNKQMDTKCIKVEPELVIRTSCGARQHWN
                     PTRVEG"
ORIGIN
        1 tcctttcagc ttcactgtat taacaccaac gtgaatcaaa atttccgctc cgtcattgga
       61 agtaataccg atggcatgtc cggtcgggaa tacggtcgta atcgttccgt taaccggaga
      121 agtcagcaca ccctctgtag gatcgatcaa gattcctttc cccatagcgc ctgaagcaaa
      181 agcaacatca gaagattgtt ccaatggcag cactttacct tgcagcggac ttacgaggat
      241 ttctttttcg atggctactt ctttttttac gggggctgtt tctgtttttg cagcttcttc
      301 ttttggatca tcaaagccca aaatcataac caatacaact gcaagtacaa aggcaacgag
      361 taagccgata acaacccaca agaacccagc tccaaaataa gttggcaacg ccagtaaact
      421 aggcagggag aaggattttg cagttgctcc gccggaagcg ataatcgcgc ccccaatacc
      481 accagaaata caagcataga tgaaaggctt tttcaatttc aaagttacac cataaatcgt
      541 aggttcagta atcccgaata cagctgccag tgtagaagaa ccagccaaag ctttcatttg
      601 agtatttcgt gatttcagga atacccccag tgttgcaccc gcttgagaaa gtacggctgc
      661 tgtaagcatt ggaagcatcg tgtcataacc caatgtttga atattggaca gcataatagg
      721 aacgaagccc cagtgtacgc cgaaaataac aaatacttgc cagaatgccc cagcaacagc
      781 tccggcaatc aatgggctta aattgtacac ccatgtaaaa ccgttcgcca agccttgact
      841 gatcaggtta ccgactggac caaaggccaa aaacgtcaac ggaacaacaa ctagcagtga
      901 tagcataggg acgataatgt ttttaaccga ttgatgaaca aaggaattaa accaacgttc
      961 cacataggac tgtacccata ccgcgagaat aattgggatt acgctggaac tatattttat
     1021 cagaatgatt ggaatcccga gaaaagccag ttttgccgga tggtccaccg ctgcaataac
     1081 atccgggtag acgagggctc cagcaactgc gaccgataca aaagcattcg tcttaaattt
     1141 acgggacgat gtaatagcta ggaatatagg caagaaataa aacacgctgt ccgaagcggc
     1201 gttcagaatg agatacgtac cgcttgcagt atcaatccaa tggagcgacg caattaaggc
     1261 cataatccct ttgagcaaac cagctccggc aagagcaccc aagagaggtg agaaaatgct
     1321 ggaaatgata tcgaccgctt tgccaagaaa attcgttttt tcggaagatt cttctttttt
     1381 cgcatttgga ttatctgcat cctgcagatt tgtttctgcc atcatatgct caaagacctg
     1441 acctacattg ttaccaatga ccacttggaa ctggccactg ctttccacca ctgtaatgac
     1501 accaggtgtt gcttccagtg cagctttgtc tgcttttgtg cgatctttta atttaaatct
     1561 caagcgtgta gcgcaatgga ataccgaatt gacattctct tcgccgccaa cgagagtcac
     1621 tatttttttg gatagctctt tatcactcat gttcagaact ccttaagtgt tattcttgct
     1681 actgatagga tttaccgttt acatttgttg ctgagatgcg ccggcgtgca tctttttaaa
     1741 cttgtaaaca agaaaaacct aaactcgtgg tgaaaactgc gcagtcctcc tataagggaa
     1801 cgtcgatttc accatcagtt taggttttgc ctgccttacc agtcacaatc catgaacgat
     1861 gaggatataa agtttttagc ctgatatgtt attacgctca gttacccgat gaatgtgaat
     1921 cgttagatat acatactcat ctttgcttaa atattgatca tatgtttttt ccagatactc
     1981 attaattttt tgggcacaag caaaagcctc ggtatatgtt tgctttacct ggttgtacaa
     2041 aaattcttca ccactgtgaa taacctcttt gcgaatcact cgcattgcaa aatattgcaa
     2101 atgggtcaaa aatctcgaat agctaaaaga agactcatcc agcacaatcc cgtaatgata
     2161 cgtaataata ttcaatatgt gttggacaat ctcggtcatt ttcagtgtag ccttcatctc
     2221 gttaccatca atccgtgcat tcaccatatg cagtgcaata aatcccgctt cgtcttcgcc
     2281 caattttaca ccgagcgtat tttcaatttt ttgtagagca tccagcccaa ctgcaaattc
     2341 ttttttgtaa aagcgtttaa tttcatacag catcgcgttt ttgagtgcca atcctttttc
     2401 ttcccgctgt atggcaaaat gaatatggtc ggtcaatgtt aaataaatgt tatcacttaa
     2461 ctccgtatcc agcacttcgg ctgcatgggt cacgatttca ttcacgacct ccagatgaga
     2521 cacaggaata tcgtttagca gctcagttag tctggccgtg aactcgtttt catttaacat
     2581 gaaaatctta tctattttat gatcatcgac ttgatcccca gccacctttt tgaaggaaat
     2641 acctcttccc atgacgatga cctctttgcc tttatcgttt ttagtcaaca ggacgttgtt
     2701 attgagcacc ttctcaataa tcattgaagt tccccctccc atcctttacc aataaaaaat
     2761 gcccaagcac aattcaacac tattgttagc aatagcactc aattgaactc aggcattgcc
     2821 cgcatcaccg gtcacaatcc ttcgatatag tgctattgta gcacaaaaaa aagcgatttc
     2881 aacatatttt attctctttc gacaaaaaat atttcatatc aaggcccatt tgcctaattt
     2941 gcaagtcaat tgtgccctta agtggtcgta cgctcaatga gactgtattc tagcgaatga
     3001 agctccattt ggcgtccaat cagctgaggg gaaagcatga aaaaggcatt ttccgcctga
     3061 gccataatgg gattttgaac cgttgtaatc cccatggtgt gcgccagctc cgtgttatca
     3121 aacccaacaa tcgccagatc ttccggtacc ctcagcaatt gtctgcgcgc ttcgcagaga
     3181 atgcccactg ctacataatc gttagcacac aagatagcct ccggaaattc ctcacgatgc
     3241 tgtaacaaat tgcgcacgac ctgttcgcca tcacgaatgt tataaataga agaatagttc
     3301 cagtgtggca gtaccggcag attgtgttca ctcatgatct gctcataggc tcgttgtctg
     3361 ctgtgagtat tgatgctgct tggacgacca aaagcattgg ctatacgtgt atagcctttt
     3421 tgtatcaaat gttttaatgc taacatgtat ccttcatact ggtccatagc gacggagcga
     3481 atatcagtat gctccattcg ttgccatgcc acgatcggtc catatttgca ataggtactc
     3541 aaaaaatcag tgtcattcac gcaggaaatg atgaccagcg catcgactct ttttcttttt
     3601 aaatcctcga aagcttgaag ctctttcttt ttgtcttctc ccgaagtata aataatggtt
     3661 tggaattcat attggcctgc gatttccaca aagctgtcca gaaatgccag cacaatttca
     3721 ttgatagttg aagtgatgat accaatctga agcgtctgac ccttggatag agagatcgca
     3781 tttcgattag gaacataatc caattcctgc attattttta aaattttagc tctggtttct
     3841 tggcttacat ggggggactg atttaacact ctggataccg tagctttgga aaagcccgcc
     3901 agttttgcaa tttgatcaag attcgacatg atgcttctcc tcacctgaga aaaaaatact
     3961 tgacatgaaa cgcgttacaa caattaggat gctttatgag ggcattacgt ctattttaaa
     4021 gcatctgtcg atgcatttca aaggagaacg gttaccgtta gttatggatt cgcattgcag
     4081 cacctgacgg gttactgact aaagtgaaaa cattaaatta aggaaagagg ttttcatacc
     4141 atgacgaaga cgctaaaagg attcccgaaa aacttcctct ggggcggggc aactgcagcc
     4201 aaccaattgg aaggtgcttt tgacgtagat ggaaaaggtc tatccagcgc agacatgata
     4261 gcctatgtac ctaaatcaga acgtaagaac gatcatgcta tagaaatttc gtccgaacga
     4321 ctgaaggaca tcttggcagg gaaggtaaac gcccgttttc caaagcgtga aggtgtggac
     4381 ttttaccacc actacaaaga agatattgcc ttgtttgcag aaatgggctt taaagtattc
     4441 cggatgtcca tccactggtc gcggattttc ccgaatggat atgatgccga gccgaatgaa
     4501 gcaggattgc aattctacga caatgtattc gatgagctgc gcaagtatgg tattgagcct
     4561 ttggtaacac tgtcgcatta tgaaacaccg ctaggtctga cacagaagta taatggctgg
     4621 ttgggacgcg aagtcgtgga tcattacgta aaatatgccg aaacggtatt tacacgctat
     4681 aaggataaag taaaatactg gctgaccttt aacgaaatta atgtcatgac tatgagcccg
     4741 tttacaggcg gcggtgtggt tattgaccgt gtagaaaaca agcaacaagc gatatatcaa
     4801 gcattgcacc atcaatttgt agcaagtgca ttggcgacca aacggggaca tgagatcatt
     4861 ccgggcgctc agatcggctg tatgctggcc cgcattgaaa gctacccaca tacgtgtaac
     4921 ccagaagata tcctgaaagc acagcatgaa aatcaaatga acctgttctt tacggatgtg
     4981 catgctcgtg ggggatatcc caactatatg aaccgctatt ttgaagaaaa taatattgtg
     5041 atccagacag aacccggcga tgccgaaatt ttgaaaaata acacggtcga ttttatctca
     5101 tttagttact atatgacctt gaccgtatcg gcagggccag aaggcgaaaa ggcagcaggg
     5161 aacctgatag gcggtgtgaa aaatccgtat ctgcagtctt ccgactgggg atggcagatc
     5221 gatccgatcg gcctgcgtgt tacactgaat acgttttatg atcgctatca aaagccactg
     5281 ttcatcgtgg aaaatggcct gggtgcgtat gataaggtag aagaagacgg ctctgtgcat
     5341 gacacgtatc gcattgatta cttgcgtcag catattgccc aaatgaagga agcgattgct
     5401 gacggtgttg atctgattgg ttacaccagc tggggaccta tcgaccttgt gagcatgtct
     5461 acgtccgaaa tgtccaagcg ctacggattt atttacgttg atctggatga tgacggtaac
     5521 ggaacgcttc aacgctccaa aaaggactca tttaactggt ataaaaatgt gatagcaacc
     5581 aacggtgaag aattataatt ccatatcgtt ttggcgggta cagcagagaa aatcctcagg
     5641 atgcaatctg ctgtacccgc tttttgtata gacactctat tgattctttc agagggcttc
     5701 acaaattttt cacttgtaat aagctgaaat ttttctgtat aatgaataaa aatttcatat
     5761 gtctggttga tgtttgcggg agatggaatg aaagttccaa ccgaaggggc aaaactctca
     5821 ggtgcttagg ctgatttaca gcaacgagca gggaccgtaa acggacagaa ctctggagag
     5881 acccttaatt gggcgccgaa ggtgcaccgc agatcacatc tgcttaaact ctcaggcaaa
     5941 aggacagaga cgcgaataac ctgtgacagg gatagcccta ggctttttat aagcttttag
     6001 aggtgaaatc ctgcacaaga tggttgtatt ttttcgtgcc tttaacctct ccaagagtcg
     6061 aatcaacaga tttgactctt ttttgttttc tactatgctg aaggagcggg ttgaaatgaa
     6121 tttggtacat gtgttagaaa cgattgacag ttggatgtgg ggagcgccgc ttctaattct
     6181 cgtcatgggc actgggttgt ggctaacgat ccgtctgaag atgcttcaga ttattcgatt
     6241 gcccttagcg ctcaagctaa ttggtaaagc gccggacgaa ggcagcgggg atgtcagtag
     6301 ctttggagca ttgagtacgg cacttgcagc tactgtaggt acgggaagta tcgtcggtgt
     6361 cgcaacagcg atcaaactgg gtgggcccgg ttcattattc tggatgctgg ttgcagcttt
     6421 tttcgggatg gcaaccaaat atgcggaagg gctattatcc gttaaatacc gtgttaaaga
     6481 ccggaacgga caattttcgg gtggaccgat gtattatatt gaaaatgggc ttggccgccg
     6541 tttcaagccg ctggcgatgt tgtttgcctt ttctggtatt cttgtagcac tatttggaat
     6601 cggtactttt ccgcaagtaa aggctatcgt ttcttctacg gaaagtagct ttggcgtgcc
     6661 aacagtagtt acagcaatca ttatttccgt gttgacggct gttgttacga ttggaggact
     6721 caaaagtatc gccaaggtat ccacaaagat tgttccattc atgtcggggc tctatatcgt
     6781 ggtttgttta atcgtactca ttaagtttgc aggagagctt cctcatgcga tcgcactagt
     6841 attacaaggg gctttctcga caacatctgc gacgggtgga tttgccggag ccacgattat
     6901 gctggcgatg cgaagcggag ttgccagagg gatctttgca aatgaagctg gtttgggaag
     6961 tgcgccaatc gcagcagcag cagctaagac gaaatggccc gcagaacaag ggctaatatc
     7021 catgacgggc gtttttatcg atacgatgat tatttgtaat ttgacaggat ttacattgct
     7081 ggttacggga atatggagtg gaaatgatga tggaggtctg atgactcagc atgcgttttc
     7141 cagtgccttt ccggctggag cagagctcgt gacgattagc cttattttat ttgcgttcac
     7201 aacgatactt ggctggaact actacgggga acgctgtgtt gaatatttgc ttggggtcaa
     7261 gtggattaaa ccataccgtt atctgttcat cgtactggtt gccggaggcg cgttcatcaa
     7321 gctcgatgcc atctggctgc tggcagatat ttttaacgcc atgatggctt ttccgaacct
     7381 gattgcactg ctcggcttgt cgggaattgt tgttgcagaa acccggactt atatgaattc
     7441 tttgtatcct aataagaaca agggtattct tgctggtgcc aatgtagggg cggctatcca
     7501 agtagaagaa aagggacaaa cggtaaattc ataaatacta aaagggagta tcctcagcca
     7561 tcacaggctt gagggtactc ctttttttag gttataagac tggtgattac cgacatttta
     7621 tttattctga atatctctta atccataacg tttacaaacc taagagttat tacatgggag
     7681 cataatcgta atttgaaaat gcgaatccgt aatagttgta tttaaataac caccatattt
     7741 ctttatcact tgctggatgt taagtaatcc atacccatgt ttttttaaag ggggattgta
     7801 tgttttggtt gagaatgctg tattgagata attacttttt gaattgcgaa cataaatcca
     7861 tagggcaata ttatcggtga aaatttccaa atgaattgaa tgctctttct ttctaggaag
     7921 ctgcattaca gcttcaatag cattatcgaa aacattacct aagacaatac atagatcatg
     7981 acttccaata ctaatatttg ccgggttaat atggatttga tggaagaaag ctatcccact
     8041 tttattagcg atgctgaaag tatgatttac taaagcatca ataacgagat gtcctgttgt
     8101 tatatgaagt tttggtgagt ctatattttt tagagtttgg ttgatgtgat taacaccctc
     8161 ttccgtcctc tgttcttgta aacaagcacg gacaaatatt aactgttttt tgaaatcatg
     8221 aatacttcgt ttgatatcac taagagatcg aattgtttct ttataacgtt tttcttgcat
     8281 cagcatttgc ttttgaaaaa agcatgagag gtttgacttt tctatcaact tgtccgttag
     8341 aaagacatta atcacgttca ttccaagaat actgatgatt gacattataa agaataaatt
     8401 atgtttcata aaagaaaata aaccgtaatg tatgagcaag ttaaacgatg ttcctattaa
     8461 tattacaaaa taatacacaa tccctatctt gtattttctt ccttttttaa aataatgaac
     8521 tactagtact gtaataagta tgaagtgtaa agaggcgaaa agtaaaaaaa ggttaactat
     8581 tggattggaa aaatgacttt gctttgttgt gctaaataaa aataaagagt aattagaaaa
     8641 cgaggtgaca ttaatgtaaa cgcaatgatt caaaaaactc acccttcctg aaaacgagaa
     8701 attataaaac gagcatacgc ctcacgaagt gatttagcgt gagaacgacc tacagggaat
     8761 tcttgttcgt ttgacataat aacagaagta gctgaaaact tacgtatatg aactaaattc
     8821 acaattattg acctatgtat aaacacaaac ggatatttta attgttcata aaccgctttc
     8881 aacgttccag aaataaaata gttgtgtgaa tccgttgcaa tacaaagttc attatggatg
     8941 taattgtttt caccttttga gatggctatg atctcagagt gtctcaatac aagatgctca
     9001 gttttatttt tcacagacag aaagtgggat actgaagaac gcatataatg acatagttta
     9061 tttatttttt ctacaaagag tttataagta aggggtttaa gtaaatattg aaatgcttgt
     9121 acttcaaaac tttctagcat gtattctgga tagttagtta gaaatatgat ttgaacttct
     9181 cggtcaggaa aaaggcgaat aagttttgca gtttcaattc ccgataattc cctcatttca
     9241 atatctaaca agataatatg aaaggggtat cgctcttgtg aactgtaaga tttgattaga
     9301 tcttccccag ataaaaagaa ttgtagatta aaatcaaagg attcacttac tgacatacac
     9361 atgaaaaagt gttgtaaaat tttatgcatt gcgggatcat cgtcacaaac agcaacttga
     9421 aacaaataga ccacctcaaa tatgttatat aaatccagta tattgtaaaa aaagtctatt
     9481 cgaagtgatg ttttacatat gaaaaaaatt accatcaggt tatggaattt ttgttagtaa
     9541 aagttcaaat gcatacttat actgtggata ggacgtagcc caggcgaggg aatggatacg
     9601 ttcttcttta ttgcttagaa taggtaacaa aaatattaat ctcacatgaa gctgacatat
     9661 ttggtcgttg agatggactt ttttgcattt caggatacaa gcttattttt tctttttgcc
     9721 ttatgctaca ttaaaagccg agaaggaaaa gctatctagt atagatattg tccagagaga
     9781 ataaagtata tgaataaact ataaaggtgt aggatggctt ttaaattcag tccggtttcg
     9841 gatgatggac atctattctt ggtggctagt gtgcactgcg agaatgctat tacaactcag
     9901 aatgagcgta catcttattt ttaaaactta tgtgaatttt gtcactagtt aatcgattca
     9961 taattacata gggaccgcat ccattctaag gagggctaaa atgaaagctt cgcaatataa
    10021 ctttattttt aatgacatta ttgaaaatac cgataaaacg gtactttata attctcgaac
    10081 aggtgcattg gcagttcttg aaccggagta ctataaacag ttttgtgaac ttacaaacaa
    10141 tggattggca ataaataatg atacttatct taaaaatctt atcgaatgtg gctatatcgt
    10201 agaagataat atgaatgaaa aagcatatgt aaaggtaaac ctcttaaaaa atcggtttga
    10261 atcttctaat ttaatgctaa caattgcccc tacaatggcc tgcaattttc gatgtgtata
    10321 ctgttttgag aaagaccaat atcataacaa aactatgagt gaagaaacag ctcaaagtat
    10381 agtcaatttt gttaaagcaa atgctagtaa acttgacact cttaatgtta catggtatgg
    10441 cggtgaaccc ttgattgcaa tgaagcagat agttaggata tcggaagatt ttttggaaat
    10501 atgtaaagaa aacaatatac aatatacggc cagtgtcatt acaaacggct atcttttaaa
    10561 taaagaaaaa gttcaaacgt taatatcatg tggagtaaat gatattcaag tcactgttga
    10621 cggtcctaaa gaagtacatg atcttagacg ccctttagta agtggaagag ggacatttga
    10681 tgtcataatg aataacctca agcaaattaa agggatgatt aagatattta tgagaataaa
    10741 tactgaccaa gacaactggt tgaatttaca tgaaatcgta ggattcttaa aggaaaattc
    10801 tttattggaa aatgtaatac cttatctagg attagttacg ccgacgaatg gaaagtatga
    10861 gggaactaag tgcttgacag acgagatgta ttcaaaattt aatttaaaat ttatgtcgga
    10921 aaatgatatc ccaattagtt atatttatcc tgcacctaaa ggtaattatt gttctgcgga
    10981 caaatataat agtttcgtta ttgatcctct tggtcattta tataaatgtt ggagcgatat
    11041 tggaattatt gagcagtgtg ttggaaatat aaatgaagat acatcagtga aatggaatac
    11101 tgagcttctt ggttgttatt tattatatga tcctactgaa gatgaaaaat gttcagactg
    11161 taagtactta cctgtgtgtt taggaggatg tcctcataat agaatggcag actttaacat
    11221 atgtgagcaa tatcgttata atttgcagga gtatattacc gagtgcacga aagtattact
    11281 ggctggacaa ttaacggaaa ataagaagga ggtttctgaa tcatgttaat gctaaaaaaa
    11341 atgtgtattg ttttatgtgg tttcttactt atggggatgc cattaggtgc ttcaagtaat
    11401 gcagcttcaa atgatgttaa gaatatcaat ctaacggcta taaattgtaa tgtcaccgtt
    11461 acaaaaactt cagcaagtga ttttagttat gagtataaca aatccttgta tactgtcact
    11521 tctacattaa gtggatctac aatttacatc acagtaaagg ggaaaggctc agctaacggc
    11581 atttccgaca gagttaatat tttaattcct gataaaagtt atgaaaaaat aacggtagaa
    11641 agtacaaagt ctggagtttc acttccagag ctaaatacta atcttgatat cacaggtgta
    11701 gatggttcct caatgtcagt tcgggtgcct gtaggatact caaaagccat tagttatgac
    11761 aatacaaaag gttcaggttc cttaactttt agtaaaggag cttcggatta cacagttaca
    11821 gttaagacga ctgcaagtgc attaagtgtt cctgcgggat ggccattgtt tagaccaaac
    11881 ttaacatata actatataaa tggtgcaggt aaagcaaaga taaatatcac gcttgaaaac
    11941 agtgcatttt ctattgcagc tcaaaagtga taagtagcat atagttttta aactgtatgt
    12001 tatttatata aattaaattt taaggaggga aaaaccatgg acgtattggt aaaaagtgct
    12061 gtacaagtaa gtgcacattg tcctttccac ggttcaagtg gctgtactct ttcttgttcc
    12121 tacaagatgt agcataagag aagtaacatt acttagcgag atgctgtttt tagcatctcg
    12181 ctaagattta cctaatatga aacataggtg atgaatatga tagtcctaga atacttgaaa
    12241 aaataccttt caaaaacgcg caagtatgta tttttttaca ttgttgttac ttcagtattg
    12301 tggattatag gaattattgt tccttacatc acaggcatat atattgatta tttagtatca
    12361 aaaagtaata taagtatcat tttatatttt gtactgttac tggggattat aaatatagta
    12421 aacattctca tacaatattt aactgccctt ttctctacga aattgaataa tttattatta
    12481 tacgaaatct gcaatgatat ctatcaaaaa atattcaaaa ctaaactgtc ggtcttcaaa
    12541 gataaggata atgcatactt agttgaccaa attaataatg attcatccac agtagttgac
    12601 tttttttcaa ataatatttc caacttagta ttgcaagtaa tcacaataat tatcagtggt
    12661 attattgttt taaaagctga tgtactacta tgcgttataa ttttctcgct tattcctttt
    12721 tatatattta catatgtggt ttttagaaaa aaattgtata aagcaaatct gaaatacaaa
    12781 aaagaagcaa atgaatacta ctctaaaaaa gtcgaacaaa ttaacaaatt ggtttttata
    12841 aagaagaatg tactctttaa tgaaatgaat gagcggctaa ataaagcatt taattcatta
    12901 tttagagttg cgacttcaca agtaaaaact aattatattt tctccaatct aaatcaattt
    12961 atattgatca tctgctatat atttgtaatc ggaattggag gtcataaagt tgtaattggc
    13021 caaatgagta tagggcagtt caccataatt aacacgtacc tttcaatgat catctcgtca
    13081 acttcatatt tattaagctt agcaagttca taccaagaga cgaaagtatc gatagaacgg
    13141 ctaaatgacg ttatgaactc tgaaaatgat atttatggta gtacaacact tgaagattta
    13201 gagaaaataa gtattaaaca attaggtgtt aaatattccg aggaaagcgt atttagagac
    13261 ttttcttatg atttttttaa ggggggaatt tacgggattt gtggtcacaa tggttcaggc
    13321 aaaacaacat tacttaatac tctgataggt ctttatagtg atctttacac aggagaaata
    13381 gcttttaata attgctccat caaagatata gatatgcttg atatgaggcg ttatagaatt
    13441 tcttatgtag aacagaatcc ggagttttta aatctaccaa taaaggaata tttgaaattt
    13501 ggaattactt tttcaaaaga gattgccagt aatcaagatg agcttataac agcttttggg
    13561 cttgaagaga taataacaaa agctaacctt gaaaatatac taataaatga aaatggaagc
    13621 aacttttctg gtggtgaaaa gcaaaaatta gctttgattc gtgcattaag taaagattct
    13681 ttcttaacga ttcttgatga gcccacatca gccttagatt caaagagtgt aagtggactt
    13741 atagaaatat tgaccaagca aaagtcaaga aggataacaa ttgtagtatc acatgaccag
    13801 agactattag cagcatgtga ccatattttg aatattgaaa cccaagagga acgtgatgat
    13861 attggattcc acagttatgg agttctttag aaacatcaaa aaacagtatg ggaattactc
    13921 acgattgttt aagttgtttc agacaaagaa taaatcctat ttgtatgatg tgggcacagg
    13981 caaagttatg gaatgcactg aaatagagta tgtatttcta aataacttac aagtgtacgg
    14041 agatatcgaa gaggtaataa aaactaccaa agttaatgat gatacattga ctattctaat
    14101 tgacttaata catgttgcgc aggaacagca tttattccaa gcacctcctc ttttatcctt
    14161 tgcactatca aaagatgagg ttttagaaaa tgcaagaagt catctagaac aggttactct
    14221 ggagttgacc gaacaatgta atatggcatg ccactattgt atatatcatt cagggaacat
    14281 agacttcagg gaatttggac gcaggcacat gtcctggcaa gtagcagagt tagcaatcga
    14341 ttatactctg aaaaactcag gtaaaaaagt ggcggtaact ttttatggcg gggagccatt
    14401 aatagaattt aaattattaa agcattgtgt agactatact ttaaaaaatg gtgctgataa
    14461 agatttaaca ttttcaatga caacaaactt aaccttaatg actgctgaaa tcgcagaata
    14521 tctatctaca gttcctaact ttggagtagt ttgtagtatt gacggtccaa aggaaataca
    14581 tgattgtagg agggtattta aaaatggtga gggcacgtat gacaaggcaa ttaatggtct
    14641 taaacatcta attaatgctt atggagaaaa gagtaattct cttatatcgc taagcatggt
    14701 aacacctaga ccagctaatg atgtagttat gaaaaaaatt caaaatttct tcaattctct
    14761 ttcgtgggta cctaaggata ttactaaaaa tatttcttat gtgagacact cgtctgacat
    14821 agaaaaaacg attactgaaa aaagctctat gcattgttat gataaccctg tagggaactg
    14881 gacaattgat ctaatgttaa ataatacttc tatatcaaaa aatactccct ttacaatcga
    14941 ttttttacac aaacaattct caataataca tgataggatt ttaactgaaa ctccttaccc
    15001 ggactattgc ttaaacggct gctgttcacc tgcctcaaga agaatttatg taacggtaaa
    15061 tggagacttt catttatgcg agcgcattgg aaaatcacct tcagttggaa acgtttatag
    15121 tggtatagac gaatctgtat taatcgatcg ttatatagac gactatggta aggagagttt
    15181 gtcccagtgc tccaaatgtt gggctatacg cctttgttcg gtttgttacg tcgaatgtta
    15241 cgatagtgat aagtttaata tcgaaaaaaa gaaaatagct tgtaggcgtt ctttagatat
    15301 gctggaacat gcattaataa gctatcatac tatcttggaa cacaaaccac atttattaga
    15361 ggaattaaac catattacat tggtgtaatt ccaatctatt atcaaaacga gtcgaaggag
    15421 gattataaat tgagaattgt aaatccattt ggaaggaagc ctttaatggc aaataccctt
    15481 ggaattgttc ctttatcttg tatttgttct tccggtgcta ataatatact tcatgacttc
    15541 ggacatggct cgaattgtgc atgtaaatgt cgctctgata ggcaaatgaa tagtagtgca
    15601 aactatgata tggctttaag ttgacctatt agagaaacgt ttatttaatt tttgaaaaat
    15661 cgcttctact ctgttaaatg agtggaagcg atttttatta atcgttagat aactatggag
    15721 gctaatttac aaggaaatat ggataacagg tagacagtac atgttcaatc gtgtgtaaac
    15781 tcagcctcga agtagtctat ttgagtgttc cgtttagagc agtcgttcca attaataaaa
    15841 tcgcacggag ctcatagttg tgcaattcct ctccagagct taagtccagt ttcgaagacg
    15901 ctttagagca agtaaaaggg gaatcaagcg aagctaatct ttgatcgctc cagcggcaag
    15961 atcggaaata aattggcggc tgatgaaaag aaacaaaata ataagaggaa gtacagccag
    16021 cagggtgcca gcaatgacca tcgcataatc cgtattgtaa atcccgttca actgcgacaa
    16081 tgcaatctgg agggtgaatt tgcgctcatc cgttaaaacg attaatggcc ataagtaatc
    16141 attccaagct cctataaagg taaatgcgcc gagaaaagcg aacgcagggc gtaaaatcgg
    16201 cagtgctaca ttccagtaca gccgaaaaaa gctgcacccg tccatacgcc ccgcatccag
    16261 gagctccttg ggaatagatt cttctgcata ctgacgaatc cagaaaatcc cgaaggcatt
    16321 taccataccc gggatgatga gcgctttgaa cgtacctacc catccaaagg aagccatcat
    16381 gacaaaggag gggacgagcg aaagttgtga agggaccatc attgtagcta gcagaatgac
    16441 gaatagcacc tttttgcccg gaaaatcaaa ctttgcgaat gcaaaaccgg ccagtgaatc
    16501 aaaaaacagc accaataggg taatcgaact ggctacaaaa agggtattca aaaaggcgcc
    16561 ggcaaaatca atctgctgca atactctcgt gatgttatcc aggaagtggc tgcccaacca
    16621 caattgtggc ggaaaacgat agatgtctga ggttgtacgg gttgccatga cgattagcca
    16681 gtaaaatgga aacatcgaca ggatgatacc taccaacagc ccagcatata aaacaatgga
    16741 ttttgcacgt gtctgcatca tgtggtaaag ctccttccat cgttattttt taccttgaac
    16801 gagtttccaa ttgatgatgg agaatagagc aatgatgaga aacatgcccc atccgacagc
    16861 agcgccatat ccaaaatagt tgttaatgaa cgactcgcgg tacaggtata aaacgatggt
    16921 catgccactt gccccggcac cgccgtcatt accgaccagg acctgtggct cggtgaacag
    16981 ctgcatccca ccgatggtgg acgtaatgac cgtaaacaaa atgactgggc gcagcatcgg
    17041 aatggtgatg cggaaaaaag cttgcgctcc ggttgccccg tctattttgg cggcctcata
    17101 cagcacatgt gggatactct ggagcccagc cagatagata atggcgttgt aacccatcca
    17161 tctccagacg accatggaag aaatggcgat ttggataccc catggcacat tcagccattg
    17221 gatcataggt agccccaaga gctgcaaaag gtagttgaga aatccaaaat tgttggcaaa
    17281 taaggcgcca aagatgatgg caacagcaac aatagatgtc acattgggca ggaagaatcc
    17341 aactcgccat aaggtgcgca ttttcacaaa aggggcataa agcagaaagg caacaatgag
    17401 tgctagaaat agcattggaa tcgtggcgta cacccagatc acaaacgtat tacctacagc
    17461 ctgccaaaat tcgttgtctg tcacaaggta acgaaagttg ccccagccgt tgtaggtcat
    17521 gtctccgatc ccgtcccatt tgtgaaacgc caggtacaat gaaaagccaa tcggaaacaa
    17581 gccaaagatg ccaaacagca aataaaatgg cgagatcgca gcataaacgg cccggtgctt
    17641 ccagatttct ctcagcatat tgtccacacg ccttttttga agttttgttt tttaacgctg
    17701 taattcccgt tgaattcgtt gcattgtttc cgtccataat gagtcgggat cggcattttg
    17761 tttggccaca ttggcaagac gacgggtcac aatgccgtgg atgacaggat agcgctcgcc
    17821 gaaatagcta ttttttacct gacgtgcgga ggcggcaaaa atgaggccag tggcctgacc
    17881 accaaagaaa ggctcgggtg tctccatgac tggatcgtca tagacgccgg gagtggatgg
    17941 gaacaggccg attttatggt aggcttccaa ttggtgttcc gggctttgca gccaggtcag
    18001 aacttcaaag gcttctttgg ggtgttggct agatttgagg atagagatga aagaccctcc
    18061 cagattgccg tctcctccag gagcacgggc gactctccat ttgcccgctg tatccggtgc
    18121 ggcttctgtg agaacttgct tcatccagat tgcccctacg aacgaggcga ttttgccgtt
    18181 attgaccgaa gcattccatt caggagtcca gccatctgca ttggcgagca gatgcttcct
    18241 gtggaaatcc acagcggttt tccagcccag gcggatgtca ggagattgat tgccgatata
    18301 acttccgtcc ggcttgaagt acaggttcgt atgttgagcg agtacctgat tgtaaacgtt
    18361 tacaatatta tcggccaaaa atgaatggct tccgaatttc tgccgaagtt gttctccggc
    18421 tgccatataa tcatcccatg tgcggatcga ggcactgacc tgttcaggat cacttggcaa
    18481 gcctgcctgt tcaaacaggt cgcttcgata gaagagggcg gtaggcccag tatccatggg
    18541 aaatgcaatc attttaccat caggagtgat gccctgattc catttccatt ccaaatattg
    18601 atccttcagt cggtctgctc cgagttcctt tagatcataa aaacgatccg cactcgggaa
    18661 tagctccacc atccagtcgt tcagagctac gatgtccggt tcaccggaac gagctgcgag
    18721 cgttgtcttc agcttggctt taaagtcacc gcctattttt tgagttttta attcaatgtt
    18781 gggaaactgt ttttctgcct ggacgagcaa ttcatcgtca atagaacggt tccagtacca
    18841 caatgtaagc gttatctttt tgctgtttga caaattagct tcagatgatt gacctttaga
    18901 ggatagggac ccactacaac cactaatcat agtgagaaaa gcaagacata ataccagcca
    18961 ttgccattgt actgtcttca catcatttcc ctccttgctg tctgaataat ctgcctgctg
    19021 aacaagttgt aaatggttta gctccatcat atgaagctgt tacccattta tgtgcattgc
    19081 cttaaccaaa aacaaaaaat tcgaaacgtt tatccataaa aaaaagcacg tgcgtctgtt
    19141 ataggaagat cgcacgtgct taaggcaggg gattagcttc atgacatcaa tcgttgtatc
    19201 tcatctttca gagcttcgga tcgagtaccg aaaataacct gtagggtacc gttcccaagc
    19261 ctgataattc ctgacgctcc gagctgctta agagcttgat cgttaaccgc tttgtcgtcc
    19321 ttgacgacaa gacgcaaccg cgtgatgcag gcatcaatgc tttggatatt gtctgaaccg
    19381 ccgagatagg ttaggacctg gcctgcctga ctggactggg tgccggatga ggcgcttgct
    19441 tttccaacgg gtatggattt gttagcctca aatagaaggg tgtcatctac atcgtcttcg
    19501 cgcccgggag tctttaggtt gaatttgagg atgatgaagc ggaacagaaa ataatagatg
    19561 agggcgaaga caagcccaat cgggatcatt cgcaatggat gggtggagag cttcatattg
    19621 accagatagt caatgagtcc tgctgaaaag gaaaagccga gtttgacatc cagtaggtat
    19681 acgactaggc cgctcagacc tgttagcaga gcatgaacgc cgtaaagcag aggtgcaatg
    19741 aacataaaag aaaattcgag gggctcagta ataccggtca ggaacgacgc cagcgcagaa
    19801 ccgataaaga tggaagcgat agctttacgt ttttccgact tggccgtatg gatgaatgcg
    19861 agagccgccg ctggcagagc gaacatcata atggggaaga agccggacat gaacataccc
    19921 gccgatgtat cgcctgcgaa aaaacgtgtc aggtcaccat gaacaacttc acctgcagca
    19981 ttggtatagt ccccaatttg aaaccatgcg atcgagttca gcacatgatg cagaccgagc
    20041 gggatcagca gtcgattggc aatcatgaac accattgacc cgattccacc aaagccaaca
    20101 atccagttgc cgaaggctgc aatgccatct tgtatcggac tccagatcat gccgagcaga
    20161 atggctaaaa tcatggtcgt gaaggcggta atcatgggga caaaacgttt gcccgaaaaa
    20221 aagccaagcc aatctggaag ttgaatatta tgatattttt tgaacagata agcagaccat
    20281 ccgccgataa aaataccgcc caatacgccc atgtccagct tgacgtcgtc tggaatatac
    20341 gcaaatatac ccggtacggc cgccaaaata cgggtcagca ccaaataggc aatgactgcc
    20401 gaaagtgcgg ctaccgcgtc gcctgccaga ccaatagcaa caccgatgga gaaaataagc
    20461 gccaggttgc cgaagatggc acccgcccct tcattcagaa aaggagtgac ataatgattc
    20521 agaaatccac caactccagg gccaagcgga atatccgttt cataattaat gagagccagc
    20581 ccttgcaaaa tccctgcggc gggtaatgta gctactggaa gcattaatga cttgccgatt
    20641 ttttgcagaa atttcagcat aacattcttc ccttcatcat caagtttggg agtgtcgtat
    20701 tcatcctgaa atccttacat tcagccattt ttttacatca taaatcgggc aatctaacat
    20761 ggtcaacgat tattttagga tatcagaaga cgtaaatccg cagttgacat cgcttacatg
    20821 cttatataat atcaaattta agttaataat cgtgacggag acaagagagc cacgcagaca
    20881 tcccatgtta cagcacaggg ttggtttgtg atggcttttc ttttttttgc gcgatgacaa
    20941 cgatcaaaat cggatgatct attgaggagg ttggttgtat gtcgccatac gcagccgaat
    21001 tcatagggac aatgattctt attgccctag gtggcggagt gtgcgcaggg gtgtccctga
    21061 aaaagtcttt tgcccacgct tccggctgga ttgtggtcgg attggggtgg gggctcgcgg
    21121 tagctattgg ggtgtatgcg gtgggtccaa tcagcggagc gcatttgaat ccggcagtta
    21181 cactcgcgtt ggcatttcag ggtagttttc catggcagga tgttcccggt tatattgtgg
    21241 ctcaggttct tggagccatg gcgggtgcag ggatcgtcat tttgcattat tggccccact
    21301 ggaaagagac ggaggacaca gcagccaaac tcagtgtatt tgcgacagga ccagctattg
    21361 atcatccgtt tggtaacgtg cttagtgaaa tgataggtac ttttatcttt gttcttgctt
    21421 tactgtcgtt tggtgccaat tcgtttacag acggccttaa accgctaatt gttggttttt
    21481 tggttgtcag tatcggttta tcccttggag gcacaacggg ctatgccatc aatccagcga
    21541 gggattttgg gccgcgtctg atgcattatt tactaccgat acccggtaag ggagcatcca
    21601 actggaaata tgcatgggtg cccattgtag gaccgctatt ggggggatct ttcgcaggtc
    21661 cattttatca ggccgttttt aaggggagta tgactccggc gttctggatt ttattaggag
    21721 ttatcgtggt tgtactcttg attaccttcc gtattagtcg tatttataaa aatcataaaa
    21781 tggatcacaa gcttacagcg taaaaacgat ggatttacac ggggagagat gaacatggga
    21841 aaatatattt tgtcactaga ccagggaacg acaagttcaa gagcgatttt gttcaatagc
    21901 gaaggagatg tggtgtactc ggcccagcgg gaatttccgc aatattttcc tcaccccggc
    21961 tgggtagagc agaatgcgaa tgaaatctgg agttctattc tgggcgttat tgcctcctgt
    22021 ctttccgaat ccggtgtaaa agcaaaacaa attgctgcca tcggcattac caatcagcga
    22081 gaatcggtgg ccgtgtggga caaaaatacc ggattacccg tgtataacgt actcgtatgg
    22141 caatcacgcc aaacctcgga tatttgcgaa gaactgaagc ggcaagggca tgaggagttg
    22201 tttcacagca aaacagggct attgatcgat ccgtattttt caggcactaa agtaaagtgg
    22261 atactggacc atgtagaagg agcgcgggaa agagcggaac gaggtgactt attatttggt
    22321 acgattgact cgtggctaat ctggaaacta tccggcggaa aggcccatgt aacagactac
    22381 tccaatgcgg ccagaacgct gatgtacaat atttatgagc taaagtggga tgaagagcta
    22441 ctggatattc tgggagttcc gaaaatcatg ttgcctgagg taaggccttc ttccgaggta
    22501 tatgcgcaca ccgtggatta tcattttttt ggtcagaatg taccgatcgc cggtgcagcg
    22561 ggtgaccagc aggcagcctt gttcggtcag gcttgttacg aaaaaggaat gatcaaaaac
    22621 acttacggta caggttgctt catgttgatg aatacgggag atcagccggt tgaatccaag
    22681 cacggtctga tcacgaccat cgcttggggg ctggaggaag gcaaagtgca atacgcactt
    22741 gaagggagtg tgtttgttgc gggctctgcg atccagtggc tgcgagatgg gctgcgcatg
    22801 ttccgtgaag cgaaggacag tgagccttat gcggcccgtg tttcctccac agaaggagta
    22861 tatcttgtac ccgcttttgt cgggctgggc agcccctact gggatagcga ggtgcgtgga
    22921 gcgatgtttg gtctgacacg tgggaccacg aaggagcatt ttatccgtgc caccctggag
    22981 tcgctcgctt atcagaccaa ggatgtgctc acagccatgg agattgattc aggtattacg
    23041 gtgaagatgt tgcgagtgga tggaggagcc gtgttgaaca atttcctgat gcaattccag
    23101 agcgatattc tggatgcgac ggtggaacgg ccagttatcc atgagacaac ggcgctgggt
    23161 gccgcgtgtc tggcagggtt ggcgatagga tactggaaga gtacagacga acttcgtaag
    23221 cgagtgagag tggaaacttc ttttacccct acgatggatg aagcaacacg tgacagcctg
    23281 tatgaaggct ggaaaaaggc tgtgaatgcg acgatggcct acaaataatg gcttaaacga
    23341 aagggctctt gttatataac tgcaaaaagg tgacttctgt attcgacagg agtcaccttt
    23401 tttaggtatg tgctatccct caacccttgt agggttccaa tgttgccggg ctccgcagga
    23461 ggtgcgaatg acgagttcgg gctccacttt aatacatttc gtatccattt gtttattcat
    23521 caggtcaaac agcaccatag cggccagacg acctattttt tgcttgtctt gttttacagt
    23581 cgtcagtgga ggatcggtat aacgacaggc ttcaatatca tcacatccta ctacggcaat
    23641 atcctcgggt accctcaagc cgctctcctt gaaagcacgg atggcaccaa aggcaagcag
    23701 gtcggtagcc gcaaaaatag cttttggtaa attttcttgc tctatccacg cctttgcgat
    23761 ctggtatcca tcctctgctg catagtcctt gccatacacg atccattccg gtctgacatc
    23821 aaggctaaac cgctttagtg atgagataaa agcttcttct ctctctttaa taaccaagga
    23881 ggggcgttct atgcctataa aacccatttc gcggtatcca ttcatgtaaa agtgctcaac
    23941 aaccttcatt gaaatctttt gattgtcgga catgatgtag caggaactgg ctccggttag
    24001 ttcgatatcg acaccgatgc aggggatagg gctggcatcg agatcaaaaa cactcttctc
    24061 cacttcgtct ccggcaataa taatgcaccc gtccactgag aaatattttg agcgagccaa
    24121 atagtcctct ccattatcca gaaatttctc attcgaaaaa aacagcaggt cgtaaccgag
    24181 caagccaatc tgctttttga aaacattaat gatgtctaca aaaaaaggat ggctaaaatc
    24241 gacattcagc ttgccagcga atataacgcc taccagatta gattttttgg tagcaagcgt
    24301 tttagccgag gaggaaggtc tatagcctgt ttcctccata attttgagta ctcgctgccg
    24361 ggtttcctca ctgatatctg tgtaattgtt tatgatcttc gaaaccgttg ctactgaaac
    24421 gcctgccatg ctagctattg tttttatatt catggaatcc tccgtaacta aactgattta
    24481 gttcatttga ccttgcattc taaaattaat gattactcgt attctatgct acctcataga
    24541 agagagtcaa ccgtgctatt ataggataaa tcctaatata ttatggataa tgaagttcga
    24601 tttaacgata gttaatgatt ttttgataat ttacaaattg ctatttacaa atacaggcta
    24661 ttcgatacat aatagtagct gtaattaact aaaccgcttt cgtaagagtg agtgcattta
    24721 ttctaagatt acagggggaa ttttgcaatg ctgaaaaagt gtttttcttt acttgttgta
    24781 accgctttaa tcgtggtatt agccgcttgc ggtaaaggta acgaagctgg gcagaacggg
    24841 aataaaaagg tcacgttaaa aattattcat tggcagcagg agaatattaa taactatata
    24901 aaggaattta ataaaaagtt tgaagagaag tatcctgatg ttcaggtgga gtatacgacg
    24961 gttcctgctg attccactta tgatcaactg atgcaaacgc gtatgaatgc gggttcaacc
    25021 ggtgatgcag atattattcc tctgaaattc agcttcgtag gcgcaccgca ggaatggtct
    25081 aagggagctg ctgatccgat gtggaagcag tggatcgagg gaggactcat tgcagatctg
    25141 tcagatcaag cttttatcaa aaactataat cctacagatg tcaaaaatgc catgacctat
    25201 aacgacaagg tatatggtgt gaacatgggg aaggtggccc tgacaggact gttttataac
    25261 aaagagattt ttgaaaaata taatcttgct gtgcccacga catgggacga actggtgaat
    25321 gttatgaagg tgctcaaaga taacggcgta gaaccgattg gtttcggcgg taaagatgta
    25381 tggcctat
//
