LOCUS       NZ_CP009163            20609 bp    DNA     circular CON 03-FEB-2024
DEFINITION  Burkholderia pseudomallei K42 chromosome 2, complete sequence.
ACCESSION   NZ_CP009163
VERSION     NZ_CP009163.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei K42
  ORGANISM  Burkholderia pseudomallei K42
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3327069)
  AUTHORS   Johnson,S.L., Baker,A.L., Chain,P.S., Currie,B.J., Daligault,H.E.,
            Davenport,K.W., Davis,C.B., Inglis,T.J., Kaestli,M., Koren,S.,
            Mayo,M., Merritt,A.J., Price,E.P., Sarovich,D.S., Warner,J. and
            Rosovitz,M.J.
  TITLE     Whole-Genome Sequences of 80 Environmental and Clinical Isolates of
            Burkholderia pseudomallei
  JOURNAL   Genome Announc 3 (1), e01282-14 (2015)
   PUBMED   25676747
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3327069)
  AUTHORS   Baker,A.L., Bunnell,A., Chain,P.S., Chertkov,O., Daligault,H.E.,
            Davenport,K.W., Davis,C., Gleasner,C.D., Johnson,S.L., Koren,S.,
            Kunde,Y.A., Mayo,M., McMurry,K.K., Robison,R., Rosovitz,M.J. and
            Warner,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-AUG-2013
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; Hgap v. 1.4
            Genome Coverage                   :: 415x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/03/2024 03:30:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,503
            CDSs (total)                      :: 6,427
            Genes (coding)                    :: 6,257
            CDSs (with protein)               :: 6,257
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 99 of 170
            Pseudo Genes (incomplete)         :: 105 of 170
            Pseudo Genes (internal stop)      :: 19 of 170
            Pseudo Genes (multiple problems)  :: 47 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:06:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2563368
            Orig. end                         :: 2583977
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009163.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from Dr. Richard Robison, Brigham Young
            University (BYU), richard_robison@byu.edu.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="15"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10609](-)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10609)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     misc_feature    complement(287..301)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.65"
                     /tool="antismash"
     misc_feature    1502..1512
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     misc_feature    complement(1648..1662)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            2231..3787
                     /gene="bcsG"
                     /locus_tag="X993_RS28470"
                     /old_locus_tag="X993_5514"
     CDS             2231..3787
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030244 - cellulose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="bcsG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004549777.1"
                     /locus_tag="X993_RS28470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5514"
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="WP_038736563.1"
                     /transl_table=11
                     /translation="MTFWNLYFILKLYLFAAGHLKPLWIANLGFALALALSAPARRRGV
                     RLLRHALALALAVPLMYREADVPPLARLVETLGGLRAFSAGYWMELVPRFVPPMLALAA
                     LGVVIGYLIVNRWLRVATFVLLALIALPVWQAGSAALARLDAAAAAVPGPAGTGRAVQP
                     QDHNAALAAFRSQESQRQVTFGRPSADPATQFDVIVLHVCSLSWDDLDVARLRNHPLLG
                     HFDYLFTNFSTAASYSGPAAIRVLRASCGQEAHADLYKPAPAQCHLFGQLAAAGFAPQT
                     LLNHDGHFDNFLQLIRENIGVPNAPMIPNADAPVAMHAFDGSAIKDDYATLANWYAKRG
                     ASPGPVALYYNTISLHDGNQLTGGRMSSLDSYPLRARKLLDDFDRFADLIAASGRRAVI
                     VFVPEHGAALRGDAKQVAGLREIPTPRIVHGPVGVRLVGFKGDHGATTVIDAPASFFAL
                     AQLLANLVSNSPFKPGVTLSQYAADLPQTRMIGENEGTVTMTTPTGYAVKTPDGVWIDE
                     K"
     misc_feature    2247..2261
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.19"
                     /tool="antismash"
     gene            3784..3978
                     /locus_tag="X993_RS28475"
                     /old_locus_tag="X993_5515"
     CDS             3784..3978
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009977638.1"
                     /locus_tag="X993_RS28475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5515"
                     /product="hypothetical protein"
                     /protein_id="WP_004528860.1"
                     /transl_table=11
                     /translation="MTNGNRNTPAARGDAPPPAHDIAGLARHVREIDPARYLDEQARLA
                     YRTALKRWPVLAKLMGLAD"
     gene            complement(4232..5065)
                     /gene="tauD"
                     /locus_tag="X993_RS28480"
                     /old_locus_tag="X993_5516"
     CDS             complement(4232..5065)
                     /EC_number="1.14.11.17"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (6-270). E-value: 4.4e-68. Score:
                     221.9. Matches aSDomain:
                     nrpspksdomains_X993_RS28480_TauD.1"
                     /codon_start=1
                     /gene="tauD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004530602.1"
                     /locus_tag="X993_RS28480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5516"
                     /product="taurine dioxygenase"
                     /protein_id="WP_004548686.1"
                     /sec_met_domain="TauD (E-value: 2.1e-66, bitscore: 221.9,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRLTLTRLTPALGAIVDDVDLSNATDALRDDIRVALAHHQVLFF
                     RGQRLSAARHRDFAAGFGDLHVHPIYPSHPDAREIMVLDNAVFDLQDNAIWHTDVTFTE
                     TPPRASILAAHTLPETGGDTLWGSGFAAYDALSGRVKAQLDGLTAQHDFTKSFPLKRFG
                     VTAEDRARWEKTRATHPSVAHPVVRTHPETGRKTLFVNEGFTTEIDGLPEEEGAALLRF
                     LFAHQSRPEFTLRWRWQPGDVAFWDNRSTIHYAVNDYGKAHRVMHRATIVGDRPY"
     aSDomain        complement(4256..5047)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_X993_RS28480_TauD.1"
                     /evalue="4.40E-68"
                     /label="X993_RS28480_TauD.1"
                     /locus_tag="X993_RS28480"
                     /protein_end="270"
                     /protein_start="6"
                     /score="221.9"
                     /tool="antismash"
                     /translation="TRLTPALGAIVDDVDLSNATDALRDDIRVALAHHQVLFFRGQRLS
                     AARHRDFAAGFGDLHVHPIYPSHPDAREIMVLDNAVFDLQDNAIWHTDVTFTETPPRAS
                     ILAAHTLPETGGDTLWGSGFAAYDALSGRVKAQLDGLTAQHDFTKSFPLKRFGVTAEDR
                     ARWEKTRATHPSVAHPVVRTHPETGRKTLFVNEGFTTEIDGLPEEEGAALLRFLFAHQS
                     RPEFTLRWRWQPGDVAFWDNRSTIHYAVNDYGKAHRVMHRAT"
     misc_feature    complement(5128..5140)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.62"
                     /tool="antismash"
     misc_feature    complement(5324..5339)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.08"
                     /tool="antismash"
     gene            5328..6338
                     /gene="tauA"
                     /locus_tag="X993_RS28485"
                     /old_locus_tag="X993_5517"
     CDS             5328..6338
                     /GO_component="GO:0009897 - external side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015411 - ABC-type taurine transporter
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0030977 - taurine binding [Evidence IEA]"
                     /GO_process="GO:0015734 - taurine transport [Evidence IEA]"
                     /codon_start=1
                     /gene="tauA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525289.1"
                     /locus_tag="X993_RS28485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5517"
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_004539426.1"
                     /transl_table=11
                     /translation="MILKRILIAASFTAAAASAVHSHAARAETVNVAYQYGADPAKLAQ
                     AGAAYEKATGWKINWRRFDSGADVVAALASGDVQLGDVGQSPFTAAVSRGVPIQAVALN
                     AITGVSEALVVRRGAHIDKPADLVGKTIATPYASNCHYALLAALKHWGIDAQRVRIVNL
                     GPTEIVAAWARGVIDAAYTWDPALGRAKASGGKVLVDSAEVGKWGAPTFDLWAVRSDFA
                     QAHPDFVSKFVKVTTQAIADYRANGKAWTSASRQVAEISRLSGAAAGDIAQLLAGNLYP
                     SAAEQASPELLGGGTADAIASTARFLKEQRKIDRVLPDYRPTVTDRFVRAAIAAR"
     gene            6359..7141
                     /locus_tag="X993_RS28490"
                     /old_locus_tag="X993_5518"
     CDS             6359..7141
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006028946.1"
                     /locus_tag="X993_RS28490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5518"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_004188097.1"
                     /transl_table=11
                     /translation="MAKLCAQQVSVVYASRRGALTALENVSMSVGSGEIVVALGASGCG
                     KSTLLSLLAGFQPPTSGRVSVDGAPVAGPGADRGVVFQDDALMPWLNVIENVAFGLRMQ
                     GVGRDARHARARDVLRLVKLAGFEQHRIDEISGGMRQRVGLARALAADPSFLLMDEPLG
                     ALDALTREHMQTLLLDVWRATGKGVFLITHSVEEAVLLATELLILSPRPGRIVARHSLD
                     FARRYAHGEPMRSIKSDPRFTEIHLALVEQLMRETEEV"
     gene            7144..7995
                     /locus_tag="X993_RS28495"
                     /old_locus_tag="X993_5519"
     CDS             7144..7995
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853486.1"
                     /locus_tag="X993_RS28495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5519"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_038736715.1"
                     /transl_table=11
                     /translation="MAATEPNADLALPLPATNAAASATARRAPRVHAGHAAALATWVAL
                     AAGWWLAARFEWVSAALLPGPEAVLRKLVVLSTEGFDDATLGEHLLASVSRIATAFALA
                     IVTAIPVGILVATNRIVRGVVDPIVEFYRPIPPLAYLPLMVVWFGIGDASKILLIYLTM
                     FAPLAIATAAGASGVSESRLRAAASLGATRVQLLRHVVLPSALPDILTGMRIALGAGWS
                     TLVAAELIAATRGLGFMVYSASRFLVTDVVIAGILVIGAIALALEIGLRALQRRLTPWR
                     AD"
     gene            complement(8334..9659)
                     /locus_tag="X993_RS28500"
                     /old_locus_tag="X993_5520"
     CDS             complement(8334..9659)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004555031.1"
                     /locus_tag="X993_RS28500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5520"
                     /product="NADH:flavin oxidoreductase/NADH oxidase family
                     protein"
                     /protein_id="WP_044491149.1"
                     /transl_table=11
                     /translation="MPDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVT
                     PQLIALYRRWSGSGAGLLVTGNVMIDGKALGEPGNVVIEDDRDLPRLREWAAAAKAHGS
                     EIWMQINHPGKQAMRGLNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYGTTA
                     AVAQQAGFTGVQLHGAHGYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVG
                     PDFPIGIKLNSADFQRGGFTEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKAS
                     TIAREAYFLAFAEKVRADVKVPLMVTGGFRSLAGMEAPLRDGALDLIGLGRILTIEPDA
                     PARLLRGEETRHRVKPLSTGVKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFL
                     LDLSSKGCAIFKARRLRASSSEASAARGSATSVAGGPRHDAH"
     misc_feature    complement(9697..9713)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            complement(10001..10609)
                     /gene="bspI3"
                     /locus_tag="X993_RS28505"
                     /old_locus_tag="X993_5521"
     CDS             complement(10001..10609)
                     /codon_start=1
                     /gene="bspI3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528852.1"
                     /locus_tag="X993_RS28505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5521"
                     /product="N-acylhomoserine lactone synthase BspI3"
                     /protein_id="WP_004528852.1"
                     /sec_met_domain="Autoind_synth (E-value: 1.1e-23, bitscore:
                     81.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYIIAGRLNELPPHVQTDLGAYRYDVFVRRLGWTIAGHSLDEHA
                     EWDEFDGPSTIHVVALDDAREICGYARLLPTTGPYLLRDVFAHLLGSSPAPQSPAVWEM
                     SRFAASRRRRSATEREPLGMAFFPSVLTVAASLGATRVVGVMTPSIERLYRRSGIALHR
                     LGNAMPGAGGSLSACSIDLPRLAFAPLGRKQCAACLAMH"
     misc_feature    10645..10654
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(10940..11632)
                     /gene="bpsR3"
                     /locus_tag="X993_RS28515"
                     /old_locus_tag="X993_5522"
     CDS             complement(10940..11632)
                     /codon_start=1
                     /gene="bpsR3"
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188690.1"
                     /locus_tag="X993_RS28515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5522"
                     /product="N-acyl-homoserine lactone dependent regulator
                     BpsR3"
                     /protein_id="WP_004188690.1"
                     /transl_table=11
                     /translation="MLSAALPESRDVRTLVETFRQAALQIGYQHHAIVELSGASHPASI
                     DVVSLHYPSEWVEHYTRNDYFAIDPVHRAAFRYSTPFSWNDVATANLRERHLLMEAEDA
                     GLDNGISIPLHQPLGRVLLVSLSGTAPTHDADAKWRNAYLLGMQFNLQFQSMRTCRPIP
                     PSVHLTDREQMCLTWVARGKSSWVIANMLDISKYTVDFHIENAMEKLNTRSRTFAAVKA
                     TRQGLIFP"
     misc_feature    complement(11684..11699)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.3"
                     /tool="antismash"
     misc_feature    11710..11724
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            11806..12075
                     /locus_tag="X993_RS38235"
     CDS             11806..12075
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525293.1"
                     /locus_tag="X993_RS38235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004525293.1"
                     /transl_table=11
                     /translation="MTLKLSANNIKCNNDCKSGVRIIEIHLAMAFDIFIPALRVFFAVC
                     NDPIGKAAGRGQIDTAIGILNRCCDAIGKFISFSSEPIFCADRE"
     misc_feature    complement(11816..11830)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.94"
                     /tool="antismash"
     misc_feature    11823..11839
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.71"
                     /tool="antismash"
     misc_feature    complement(11824..11833)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.85"
                     /tool="antismash"
     misc_feature    11998..12000
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12400..14007)
                     /locus_tag="X993_RS28520"
                     /old_locus_tag="X993_5523"
     CDS             complement(12400..14007)
                     /NRPS_PKS="Domain: AMP-binding (8-434). E-value: 6.8e-92.
                     Score: 300.1. Matches aSDomain:
                     nrpspksdomains_X993_RS28520_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004551903.1"
                     /locus_tag="X993_RS28520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5523"
                     /product="acyl-CoA ligase (AMP-forming), exosortase A
                     system-associated"
                     /protein_id="WP_044491151.1"
                     /sec_met_domain="AMP-binding (E-value: 6.4e-95, bitscore:
                     315.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNFFDLVEQAACRTPDAEALVAGDARLTYRALAALGLAFAERLQ
                     ALEIAQGERLAIFLDKRIETVVAMLGAAAAGVVFVPINPALKPEQVHHILVDSGARCLV
                     TSSLRARILGDGVLAGMPYVILTDAKTLAPAPASRTTFLRWMQPDAPPESVANRHASAA
                     PEPRADTIDADLAALLYTSGSTGRPKGVMLSHRNLLEGAWSVAQYLRHTAQDRILAALP
                     LSFDAGLSQLTTAWAAGASAVLVNYLMPADVVEICVRERITGFAGVPPLWIQLARAAWP
                     GEARARLRYFANTGGHLPRPVLHALRELFPSASPYLMYGLTEAFRSTYLDPAEVDRRPD
                     SIGKAVPNARILVVREDGAPCAPNEVGELVHVGACVTLGYWNDPARTALRYRPSPEAKP
                     GGAPRETAVWSGDLVRRDDDGFLYFVARNDAQIKSSGYRISPEEIEEVAHASGFVAEAV
                     ALGVPHDELGESITLVVVPLDADTFRPDALRARCAQQLPPYMVPHTIATRTSLPRNPNG
                     KFDRVALRADAANLVETL"
     CDS_motif       complement(12673..12738)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_X993_RS28520_0003"
                     /evalue="8.30E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="X993_RS28520"
                     /protein_end="445"
                     /protein_start="423"
                     /score="21.5"
                     /tool="antismash"
                     /translation="FVARNDAQIKSSGYRISPEEIE"
     aSDomain        complement(12706..13983)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_X993_RS28520_AMP-binding.1"
                     /evalue="6.80E-92"
                     /label="X993_RS28520_AMP-binding.1"
                     /locus_tag="X993_RS28520"
                     /protein_end="434"
                     /protein_start="8"
                     /score="300.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQAACRTPDAEALVAGDARLTYRALAALGLAFAERLQALEIAQGE
                     RLAIFLDKRIETVVAMLGAAAAGVVFVPINPALKPEQVHHILVDSGARCLVTSSLRARI
                     LGDGVLAGMPYVILTDAKTLAPAPASRTTFLRWMQPDAPPESVANRHASAAPEPRADTI
                     DADLAALLYTSGSTGRPKGVMLSHRNLLEGAWSVAQYLRHTAQDRILAALPLSFDAGLS
                     QLTTAWAAGASAVLVNYLMPADVVEICVRERITGFAGVPPLWIQLARAAWPGEARARLR
                     YFANTGGHLPRPVLHALRELFPSASPYLMYGLTEAFRSTYLDPAEVDRRPDSIGKAVPN
                     ARILVVREDGAPCAPNEVGELVHVGACVTLGYWNDPARTALRYRPSPEAKPGGAPRETA
                     VWSGDLVRRDDDGFLYFVARNDAQIKS"
     CDS_motif       complement(12838..12921)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_X993_RS28520_0002"
                     /evalue="7.90E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="X993_RS28520"
                     /protein_end="390"
                     /protein_start="362"
                     /score="27.8"
                     /tool="antismash"
                     /translation="PNEVGELVHVGACVTLGYWNDPARTALR"
     CDS_motif       complement(13423..13482)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_X993_RS28520_0001"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="X993_RS28520"
                     /protein_end="195"
                     /protein_start="175"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AALLYTSGSTGRPKGVMLSH"
     misc_feature    complement(14248..14268)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.65"
                     /tool="antismash"
     gene            complement(14603..15385)
                     /locus_tag="X993_RS28525"
                     /old_locus_tag="X993_5524"
     CDS             complement(14603..15385)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188398.1"
                     /locus_tag="X993_RS28525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5524"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_044491152.1"
                     /transl_table=11
                     /translation="MNTLSEPRVPAARAHDETASGAAREAALARRIDALPWASIEQDLE
                     RDGHAIVHGLLAPRTCEALAALYARDALFRSRVTMARHGFGRGEYQYFGYPLPRMVHAL
                     RTALYPHLAPIANRWHAQMRIDARFPAEHAHFIERCRAAGQLRPTPLLLRYREGDYNCL
                     HQDLYGEHVFPLQAAVLLSKPGADFAGGEFVITEQRPRMQSRADVVPLEQGDAVVFAVH
                     HRPVQGARGVYRVNLRHGVSRVRSGQRHTLGIIFHDAP"
     misc_feature    15372..15383
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.02"
                     /tool="antismash"
     gene            complement(15535..17121)
                     /locus_tag="X993_RS28530"
                     /old_locus_tag="X993_5525"
     CDS             complement(15535..17121)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188605.1"
                     /locus_tag="X993_RS28530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5525"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_044491153.1"
                     /transl_table=11
                     /translation="MNPLLSAAASEELGRTRHLGVALLVALLAAGVAYVFVHLFADLAP
                     VGPRSAFPYLLLGVALAIALGFEFVNGFHDTANAVATVIYTHSLTPNVAVIWSGIWNFL
                     GVMASTGAVAFGILQLLPVELILQVGHGAGFAMVFALLIAAIAWNLATWYFGLPSSSSH
                     TLIGSIIGVGLANQLMHGPSGTSGVDWAQAAGVGQSLLLSPLVGFLCAALLLAALKALV
                     RVPALYREPQTNEPPPFWVRCLLILTCTGVSFAHGSNDGQKGTGLIMLILIGTVPTAYA
                     LNKAVTPGETQTFIAVAHRASETLARYAGAAQPSPNPRADVEAYVQSRRLSDATLPAVR
                     RLSDALAAEVGATGSIAKVPEGQADNVRNTMYLVSEALRLMEKTGRPAFSPADRLALDD
                     YRRQLDHATKFIPTWVKVAVAIALGLGTMVGWRRIVVTVGEKIGKQHLTYGQGASAEVV
                     AMLTIGAADAYGLPVSTTHVLSSGVAGTMAANGSGLQWSTVRSLVLAWVLTLPASIVLA
                     GALYWAFHALT"
     misc_feature    complement(17135..17149)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.41"
                     /tool="antismash"
     gene            complement(17500..17904)
                     /locus_tag="X993_RS28535"
                     /old_locus_tag="X993_5526"
     CDS             complement(17500..17904)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (10-121). E-value:
                     2.8e-14. Score: 45.7. Matches aSDomain:
                     nrpspksdomains_X993_RS28535_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009934737.1"
                     /locus_tag="X993_RS28535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5526"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_004528843.1"
                     /transl_table=11
                     /translation="MTEAEPIRLEQFVARPPAQVWAALTTPAALARWWAAGDVRPVPGH
                     RFTLDMGPWGRQPCEVIAVEPERRFAIAFAQRTLDTTITWRLEPAPGGTRVCFEHAGFD
                     LDAPQARIAYDGMKRGWPSVLARIEQAIDG"
     aSDomain        complement(17542..17874)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_X993_RS28535_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.80E-14"
                     /label="X993_RS28535_Polyketide_cyc2.1"
                     /locus_tag="X993_RS28535"
                     /protein_end="121"
                     /protein_start="10"
                     /score="45.7"
                     /tool="antismash"
                     /translation="QFVARPPAQVWAALTTPAALARWWAAGDVRPVPGHRFTLDMGPWG
                     RQPCEVIAVEPERRFAIAFAQRTLDTTITWRLEPAPGGTRVCFEHAGFDLDAPQARIAY
                     DGMKRGW"
     gene            complement(18184..18648)
                     /locus_tag="X993_RS28540"
                     /old_locus_tag="X993_5527"
     CDS             complement(18184..18648)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188527.1"
                     /locus_tag="X993_RS28540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5527"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_004188527.1"
                     /transl_table=11
                     /translation="MIELDKTDRAILAAVQLDGRIPVARLADSVGLSETPCARRLKRLE
                     SDGYIERYRAQLSRNALGFGVVAFVLLRCSVHDRSVANRFEREVLGIPRILSCHNVSGS
                     ADYLLQVVAHDLDDYGTFLRETLRVLPGVTSIESALSLREVKREAELPIP"
     misc_feature    complement(18667..18678)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.57"
                     /tool="antismash"
     gene            18782..19408
                     /locus_tag="X993_RS28545"
                     /old_locus_tag="X993_5528"
     CDS             18782..19408
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525297.1"
                     /locus_tag="X993_RS28545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_5528"
                     /product="LysE family translocator"
                     /protein_id="WP_004528842.1"
                     /transl_table=11
                     /translation="MFSAHLLLVYVAAVVAVYAVPGPDMAFVLQTGIGRGARHGAAAAA
                     GLGLARAVHVTLSACGVAALLKSAPWLYEAVRYGGALYLAYVAVQIFRSPAFALSAADA
                     AAPAARLRHTFVKGLLTNLLNPKALLFCSVLLPQFVQRGGAPVIAQMAVLGAVLVLAGL
                     CFDLACVAGATRIAEWLRAHPLAQLAQRWTFSAVLLGFALRLSID"
ORIGIN
        1 ccgcgcgcgg cggcgcgtcg acgcctggct cgcccgtctg ccgtggcacc gctggggcgc
       61 gcgcctcgag cacggcgcgc agcgggccgt cgcacgccgc tggctgttgc cggcgagcgc
      121 ggcggcgggc gttgcgctgt ggctcgcggc cggcacgtcg ccgctcgcgc ccgccggcca
      181 gttcgcgttc ttcgcgacgc tcgccgcgct cgcgctcgcg ctgcgccgcg tgcccggccg
      241 cttgccgacg ctcgcgctcg cgacgttcgc gctgctcgcg atggcccgct acatctggtg
      301 gcgcagcacc gagacgctcg atttgcgcac accggtcgag gcgtgcgtcg gctatctgct
      361 gtacgcggcc gaggcgtaca cgtggctcat cctcgtgctc ggcttcgtgc agaccgcgtg
      421 gccgctcgag cgcccggtcg cgcgcctgcc ggacgatccc gccggctggc cgagcgtcga
      481 cgtctacatt ccgacgtaca acgagccgct cgcggtcgtg aaaccgacga tcttcgccgc
      541 gcaaagcctc gattggccgg cggacaagct caacgtctat ctgctcgacg acggccgccg
      601 cccggagttc gaggcgttcg cgcgcgacgc gggcatcggc tatctgacgc gcgacgacaa
      661 tcgccacgcg aaggccggca acatcaacag cgcacttgcg cgcacgcacg gcgaatacat
      721 cgcgatcttc gactgcgatc acgtgccgac gcgctcgttc ctgcagacga cgatgggcgc
      781 gttccttcgc gatccgaact gtgcgctcgt gcagacgccg catcatttct tctcgccgga
      841 cccgttcgag cgcaacctcg gcacgttccg ccgcgtgccg aacgagggca gcctgttcta
      901 tggcctcgtg caggcgggca acgatctgtg gaacgccgcg ttcttctgcg gttcgtgcgc
      961 ggtgctcaag cgcggcccgc tcgaagcaat cggcggcgtc gcgatcgaga ccgtcaccga
     1021 ggatgcgcac accgcgctca agctgcaccg ccgcggctac acgagcgcct atctgccgac
     1081 cgtgcaggcc gccggcctcg cgaccgaaag cctcgcgggc cacatccggc agcgcgcgcg
     1141 ctgggcgcgc gggatggcgc agatcttccg gatcgacaac ccgttcgtcg gccgcggcct
     1201 cggcttcttc cagcgcgtgt gctacggcaa cgcgatgctg catttcttct acggcatccc
     1261 gcggctcgtg ttcctgacga tgccgatcgc gtatctgttc ttccatctgt atttcatcaa
     1321 cgcgtcggcg ctcgcgctcg cgagctacgt gctgccgtac atggcgctcg cgcacgtcgc
     1381 gaacgcgcgg atgcaggggc gctttcggca ttcgttctgg gccgaggtgt acgaatcggt
     1441 gctcgcgtgg tacatcgcgc tgccgacgac gctcgcgttc ctgagcccga ggcacggccg
     1501 cttcaatgtg accgcgaagg gcgggcgcat cgacgaaggc tacgtcgact gggcgacgtc
     1561 caggccctat ctcgcgctgt tcgtgctgaa cgtcgcggcg atcgcggcgg gcggcgtgcg
     1621 tctcgccgcg agcggcggcg acgaagcgtc gacgatcctg atgaacgtcg cgtgggcgtt
     1681 gtacaacctc gcgatgctcg gcgcggcgct cgcggtcgcg cgcgaggcga aacaggtgcg
     1741 cgtcacgcac cgggtcgcga tgcgggtgcc ggcgacgctg ttgctcgccg acggcacgac
     1801 ggccgcgtgc cacacgaagg attattcggc gggcggcttg gggctcgacg cggtgccgct
     1861 cgtgcgcatc gcgctcggcg atacgctcga cgtatgcgtg agccgcggcg atcgcccgtt
     1921 ccattttccg gtgcgcgtga cccgcgtcga cgccgcgcat ctcggcgtgc agttcgagcc
     1981 attgacgctc gagcaggagc ggcagctcgt gcagtgcacg ttcggccgcg cggatgcgtg
     2041 gctcgactgg cgcgacgcgc gcgccgagca cgacgatgcg ccgctgcgcg ggctgaagga
     2101 ggtgctgtcg atggggttcg aaggctacgc acggatgctg cgggccgcga cgagcgcggt
     2161 gcgggcgcgg cgcgcggccg accggacgcg tcattgacgc gcggattcaa ctgatgacgg
     2221 agtcgcgtcg atgacgttct ggaatctgta tttcattctg aagctctatc tgttcgcggc
     2281 gggccacttg aagccgttgt ggatcgcgaa tctcggtttc gcgctggcgc tcgcgctgag
     2341 cgcgccggcg aggcggcgcg gcgtgcggct gctgcgccac gcgctcgcgc tggcgctcgc
     2401 ggtgccgctg atgtatcgcg aagcggacgt gccgccactc gcgcggctcg tcgaaacgct
     2461 cggcggcctg cgcgcgttca gcgccggcta ctggatggag ctcgtgccgc gcttcgtgcc
     2521 gccgatgctc gcattggccg cgctcggcgt cgtgatcggc tatctgatcg tcaatcgctg
     2581 gctgcgcgtg gcgacgttcg tgctgctcgc gctgatcgcg ctgccggtgt ggcaggcggg
     2641 cagcgcggcg ctcgcgcggc tcgacgcggc tgccgcggcc gtgcccgggc cggccggaac
     2701 gggccgcgcc gtgcagccgc aggatcacaa cgcggcgctc gccgcgttcc gctcgcagga
     2761 atcgcagcgg caggtgacgt tcggccggcc gagcgccgat ccggcgacgc agttcgacgt
     2821 gatcgtgctg catgtgtgct cgctgtcgtg ggacgacctc gacgtcgcga ggctgcgcaa
     2881 tcatccgctg ctcggccatt tcgactatct gttcacgaat ttcagcacgg cggcgagcta
     2941 cagcggcccg gccgcgatcc gcgtgctgcg cgcgagctgc gggcaggagg cgcacgcgga
     3001 cctgtacaag cccgcgcccg cgcagtgcca tctgttcggg caactcgcgg ccgccggctt
     3061 cgcgccgcag acgctgctca accacgacgg ccacttcgac aactttctcc agttgatccg
     3121 cgagaacatc ggcgtgccga acgcgccgat gatcccgaac gcggacgcgc ccgtcgcgat
     3181 gcacgcgttc gacggctcgg cgatcaagga cgactacgcg acgctcgcga actggtacgc
     3241 gaaacgcggc gcgagccccg gccccgtcgc gctgtactac aacacgatca gcctgcacga
     3301 cggcaatcag ctgacgggcg gccggatgtc gagcctcgat tcgtacccgc tgcgcgcgcg
     3361 caagctgctg gacgacttcg accgcttcgc ggatctcatt gccgcatcgg ggcggcgcgc
     3421 ggtgatcgtg ttcgtgcccg agcacggcgc ggcgctgcgc ggcgacgcga aacaggtggc
     3481 ggggctgcgc gagattccga cgccgcggat cgtgcacggg ccggtcggcg tgcggctcgt
     3541 cggcttcaag ggcgaccacg gcgcgaccac cgtgatcgac gcgccggcga gcttcttcgc
     3601 gctcgcgcaa ctgctggcga atctcgtgtc gaacagcccg ttcaagccgg gcgtgacgct
     3661 gtcgcaatac gcggccgatc tgccgcagac gcgaatgatc ggcgagaacg agggcacggt
     3721 gacgatgacg acgccgacgg gctacgcggt gaagacgccg gacggcgtat ggatcgacga
     3781 aaaatgacga acgggaatcg gaacacgccg gcggcgcgcg gcgacgcgcc gccgccggcg
     3841 cacgacattg cggggctcgc gcgccacgtg cgcgagatcg atccggcgcg ctatctcgac
     3901 gagcaggcgc ggctcgcgta ccgcacggcg ctcaagaggt ggccggtgct cgcgaagctg
     3961 atggggctcg cggattgacg cgcgagccgc gccccgcgac gcgcgcgacg gcgcgcgccc
     4021 gcggcaggcg aatggccggc cgacgagccg ccggtgaacg agcggggcga cgaacggagc
     4081 gccatgcggc gccgatgggc gggccgatga acgggccgat gaacgagccg atacggcagg
     4141 cccgcgaacg agccggcgaa cgaagcggcg agccgaccga cgaacgaacc cgcggccggc
     4201 gaagcctctc cggaatcccc gcgccgcccg ctcaatacgg cctgtcgccg acgatcgtcg
     4261 cgcggtgcat cacccgatgc gctttgccgt agtcgttcac cgcgtaatgg atcgtcgagc
     4321 ggttgtccca gaacgcgacg tcgcccggct gccagcgcca gcgcagcgtg aactcgggcc
     4381 gcgactgatg cgcgaacagg aagcgcagca gcgcggcgcc ttcctcttcg ggcagcccgt
     4441 cgatctcggt cgtgaagcct tcgttgacga acagcgtctt gcggccggtc tccgggtgcg
     4501 tgcgcacgac gggatgcgcg acgctcggat gcgtcgcgcg cgtcttctcc cagcgcgcgc
     4561 gatcctcggc ggtgacgccg aagcgtttca gcggaaacga cttcgtgaaa tcgtgctgcg
     4621 cggtgaggcc gtcgagctgc gccttcacgc gcccggacag cgcgtcgtac gcggcgaagc
     4681 cgctgcccca cagcgtgtcg ccgcccgtct cgggcagcgt gtgcgcggcg aggatcgacg
     4741 cgcgcggcgg cgtctcggtg aatgtcacgt ccgtatgcca gatcgcgttg tcctgcaggt
     4801 cgaacacggc gttgtcgagc accatgatct cgcgcgcgtc cggatgcgac ggatagatcg
     4861 ggtgcacgtg cagatcgccg aatccggccg cgaagtcgcg atgccgggcc gcgctcaggc
     4921 gctggccgcg gaagaacagc acctgatggt gcgcgagcgc gacgcggatg tcgtcgcgca
     4981 gggcgtcggt cgcgttcgag aggtccacgt cgtcgacgat cgcgccgagc gcgggcgtga
     5041 gtcgggtcaa tgtcagtcgg gtcatcgtcg gtccggatat cgtcggtgcg cctcagtgcg
     5101 cctcgcatgg cggaaagccg ccaagtctcg caaaacgcgt tcgtttggtg aaccaacgaa
     5161 atccgcattg cttatcgtcg cgccgggatt gcggccggct tggcgccatc gccgaatgcg
     5221 ccgtctcata tccttcgcag atttcgttgt ttaacggacg gcgcgcaagc cggtaatctc
     5281 gacggccatc cgaattcaac gcatccagca gaagggaagg cccgttcatg attctcaagc
     5341 gcatcctcat cgccgcgtct ttcaccgccg ccgcggcctc ggccgttcat tcgcacgccg
     5401 cccgggcgga gacggtgaac gtcgcctatc agtacggcgc cgatccggcg aagctcgcgc
     5461 aggcgggcgc cgcgtacgag aaggccaccg gctggaagat caactggcgc cgcttcgatt
     5521 cgggcgcgga tgtcgtcgcg gcgctcgcct cgggcgatgt ccagctcggc gatgtcgggc
     5581 agagtccgtt taccgcggcg gtgtcgcgcg gcgtgccgat ccaggcggtc gcgctgaacg
     5641 cgatcaccgg cgtgtccgag gcgctcgtcg tgcgccgcgg cgcgcatatc gacaagccgg
     5701 ccgatctcgt cggcaagacg atcgcgacgc cttatgcgtc gaactgccat tacgcgttgc
     5761 tcgccgcgct caagcactgg ggcatcgatg cgcagcgcgt gaggatcgtg aatctcgggc
     5821 cgaccgagat cgtcgccgca tgggcgcgcg gcgtgatcga cgccgcctat acgtgggacc
     5881 cggcgctcgg ccgcgcgaag gcgagcggcg gcaaggtgct cgtcgattcg gccgaagtcg
     5941 gcaagtgggg cgcgccgaca ttcgatctgt gggcggtgcg cagcgatttc gcgcaagcgc
     6001 atccggattt cgtgtcgaag ttcgtgaagg tgacgacgca ggcgatcgcc gactatcgcg
     6061 cgaacggcaa ggcatggacg agcgcgtcgc ggcaggtcgc cgaaatctcg cggctgagcg
     6121 gcgcggcggc gggcgacatt gcgcaactgc tcgccggcaa tctctacccg agcgcggccg
     6181 agcaggcgtc gcccgagctg ctcggcggcg gcacggccga cgcgatcgcg tcgaccgcgc
     6241 gcttcctgaa ggagcagcgc aagatcgacc gcgtgctgcc cgattaccgg ccgacggtga
     6301 cggaccggtt cgtccgcgcg gcgatcgccg cgcgctgaga cgacgcggcg gcatcggcat
     6361 ggcgaagctt tgcgcgcaac aggtatccgt cgtctacgcg tcgcggcgcg gcgcgctgac
     6421 ggcgctcgag aacgtatcga tgtcggtcgg cagcggcgag atcgttgtcg cgctcggcgc
     6481 gtccggctgc ggcaagagca cgctgctgtc gctgctcgcc ggctttcagc cgccgacgtc
     6541 gggccgcgtg agcgtcgacg gcgcacccgt cgcggggccc ggcgccgatc gcggcgtcgt
     6601 gtttcaggac gacgcgctga tgccgtggct gaacgtgatc gagaacgtcg cgttcgggct
     6661 gcggatgcaa ggcgtcggcc gcgacgcacg ccacgcgcgt gcgcgcgacg tgctgcggct
     6721 cgtgaagctc gccggcttcg agcagcatcg gatcgacgag atttcgggcg gcatgcggca
     6781 gcgcgtcggg ctcgcgcgcg cgctcgccgc ggacccgtcg ttcctgctga tggacgagcc
     6841 gctcggcgcg ctcgacgcgc tcacgcgcga gcacatgcag acgctgctgc tcgacgtgtg
     6901 gcgcgcgacg ggcaagggcg tgtttctgat cacgcacagt gtcgaggaag cggtgttgct
     6961 cgcgaccgag ctgctgatcc tgtcgccgcg cccgggccgg atcgtcgcgc ggcattcgct
     7021 cgacttcgcg cggcgctacg cgcacggcga accgatgcgc tcgatcaaga gcgatccgcg
     7081 cttcaccgaa atccatctcg cgctcgtcga gcaactgatg cgcgaaaccg aggaggtttg
     7141 acgttggccg ccactgaacc gaatgccgat ctcgcgctgc cgctgccggc aaccaatgcg
     7201 gccgcgagcg cgacggcgcg ccgcgcgccg cgcgtgcatg cgggccacgc ggccgcgctc
     7261 gcgacgtggg tcgcgcttgc cgccggctgg tggctcgccg cgcgcttcga atgggtatcg
     7321 gccgcgctgc tgccgggccc cgaggccgtg ctgcgcaagc tcgtcgtgct gagcaccgag
     7381 ggtttcgacg acgcgacgct cggcgaacat ctgctcgcga gcgtgtcgcg gatcgcgacg
     7441 gcgttcgcac tcgcgatcgt caccgcgatc ccggtcggca tcctggtcgc gacgaaccgg
     7501 atcgtgcgcg gcgtcgtcga tccgatcgtc gagttttacc ggccgattcc gccgctcgcg
     7561 tatctgccgt tgatggtcgt ctggttcggg atcggcgacg cgtcgaaaat cctgctgatc
     7621 tatctgacga tgttcgcacc gctcgcgatc gcgaccgccg cgggcgcgag cggcgtatcg
     7681 gaaagccgcc tgcgcgcggc cgcgtcgctc ggcgcgacgc gcgtgcaact gctgcgccac
     7741 gtcgtgctgc cgagcgcgct gccggacatc ctgaccggca tgcgcatcgc gctcggcgcg
     7801 ggatggtcga cgctcgtcgc ggcggagctg atcgcggcga cgcgcgggct cggcttcatg
     7861 gtgtattccg cgtcacggtt cctcgtgacg gacgtcgtga tcgcggggat cctcgtgatc
     7921 ggcgcgatcg cgctcgcgct ggaaatcggc ttgcgcgcgc tgcagcggcg attgacgccg
     7981 tggcgggccg attagcgcgg cgcgtttgcg atgcggtggg gggcaggggc gcggccgatc
     8041 gaccggagcc gccgagatcg caccggcgtt gcgccggttc gtggcggtcc gtgacgatgt
     8101 gcggcggttc atctgctatc acgcgcgcgc cgcttcgttt catcggcgtt tcgccttatc
     8161 ccttatcgtc gatgagcgat gagcggcgaa gttgatatcg acatcggcct ggctatccac
     8221 cgcggcttca acgcgcgaag catcgagcaa agcgcattcg atgcgccgat gccgcgcgcc
     8281 gcgcggcgtt cactcggccg ggcggcgccg ttgcgcgagg cgggtcgccc cgctcaatgc
     8341 gcatcgtgcc gcgggccgcc ggcgaccgac gtcgccgaac cccgcgcggc cgacgcttcg
     8401 gaggacgaag cacgcaggcg gcgcgccttg aagatcgcgc agcccttcga cgacaggtcg
     8461 agcaggaacg atttcagcgc attctcgtcg ggaatcggat tgcgcccctt gccgattcga
     8521 tggagctgcc gcgtatacca cgtgacttcg agcgaaccga ggctatcgaa gtatttgacg
     8581 cccgtgctga gcggcttcac gcgatggcgc gtttcctcgc cgcgcagcag gcgcgcgggc
     8641 gcgtcgggct cgatcgtgag gatacgcccg aggccgatca ggtcgagcgc gccgtcgcgc
     8701 agcggtgcct ccatgccggc gaggctgcga aagccgcccg tgaccatcaa cggcaccttc
     8761 acgtccgcgc gcaccttctc ggcgaacgcg aggaagtacg cttcgcgcgc gatcgtcgac
     8821 gccttgcggt cgccgagctg catcacgggc gtttcgtagg tgccgccgga aatctcgatc
     8881 agatcgatgc ccgcctcggc gagcgcgcgg atcacgtcga gcgattcttc ctcggtgaag
     8941 ccgccgcgct ggaaatcggc cgaattgagc ttgatgccga tcggaaaatc ggggcccacc
     9001 cggcgccgca cttccgcgta caccgcgagc acgaagcgcc ggcggttctc cgcgctgccg
     9061 ccccattcgt cggtgcgctg attgtgctgc ggcgacagga actggttgat cagatagccg
     9121 tgcgcgccgt gcaactgcac gccggtgaag cccgcctgct gcgcgacggc ggccgtcgtt
     9181 ccgtagcgcc ggatcagcgc gtcgatctcg tccaccgtca gcgcgcgcgg caccgcgaaa
     9241 tacggcgaaa gcttcggccc gaagccgatc gccgacggcg cgacggtttc ctcgttgagt
     9301 ccgcgcatcg cctgcttgcc gggatgattg atctgcatcc agatctcgct gccgtgcgct
     9361 ttcgcggccg cggcccattc gcgcagacgc ggcagatcgc ggtcgtcctc gatcacgacg
     9421 ttgccgggct cgccgagcgc cttgccgtcg atcatcacgt tgccggtgac gagcagcccc
     9481 gcgcccgaac ccgaccagcg ccggtacagc gcgatcagct gcggcgtcac acggccgtcg
     9541 tgcccgcaca gcgcttcgct cagcgccgat ttcgcgaggc ggttcttcag cacggtgccg
     9601 ttcggcagcg tgagcggctg cgcgagcaac gcggccgcgg tgggattcga atcgggcatg
     9661 gcatgacgct ccggttgggt cgacgaccga aaatccatcg agtaatgtta catcgattga
     9721 tgtattggtt gggatcgtaa gttcaaaatc ggaactgagt caagacggag cgacccgcac
     9781 ggcgatgggc gtgccggggc gggcgagccg ggcgacgggc ggcggcccgc gtccgtagcg
     9841 gcccgccgcc cggcggcgcg ccggcggtcc ggttagagga gaacgtccaa ttcggcggcg
     9901 cgcggcgtcg cgacgcaccg ggcgatggcg tcaggcgagc gcgtcgacat cggcaaaaac
     9961 gacaagacgc gtgtcttgcc cgatgcgccc gccttcctgg tcaatgcatc gccaggcacg
    10021 ccgcgcactg cttgcggccc aacggcgcga acgcgaggcg cggcagatcg atcgagcatg
    10081 cggacaggct gccgcccgcg cccggcatcg cgttgccgag gcgatgcagc gcgatgcccg
    10141 agcggcggta caggcgttcg atcgatggcg tcatcacgcc gaccacgcgc gtcgcgccga
    10201 gcgacgcggc caccgtgagc accgacggaa agaacgccat gccgagcggc tcgcgctcgg
    10261 tcgcgcttcg ccgccgccgc gacgcggcga agcgcgacat ttcccagacg gcaggcgatt
    10321 gcggcgcggg cgacgagccg agcagatgcg caaacacgtc gcgcagcaga tacgggcccg
    10381 tcgtcggcag caggcgtgcg tagccgcaga tctcgcgcgc gtcgtcgagc gcgacgacat
    10441 gaatcgtcga cggcccgtcg aactcgtccc actccgcatg ttcgtcgagc gagtggccgg
    10501 cgatcgtcca gccgagccgg cgcacgaaca cgtcgtagcg atacgcgccg agatcggtct
    10561 ggacgtgcgg cggcagttcg ttcaatcggc ccgcgatgat gtatgacatg gcgcttggtt
    10621 ctccgatgga tcgatcgtcg gcgcgaaggc ggcgcgcgtt ccgatcgcgt atgagcggtg
    10681 agggtcgaga agcacgcgtg cgcggtctcg aaggctgttg cgcgacacga aggcgcggcg
    10741 atacggcgat acggcaatgc gcgcgcgcgg cgcggcctcg ccgcgaggcg cgacgagggc
    10801 gggcggcggg cggcggcgtt cggcgcgcag gccggcgcgg catcgatcgg cagtccgatg
    10861 caagcggccg gttgcatcgc gtcggcgcgc ggtggcggat gaaacgggcg gcgctaacgg
    10921 atccggatgg atcgcgcgct catggaaaga tgagcccctg ccgcgtcgcc ttcacggcgg
    10981 cgaacgtgcg gctgcgcgtg ttgagcttct ccatcgcgtt ctcgatgtgg aagtcgaccg
    11041 tgtatttgga gatgtcgagc atgttcgcga tgacccacga cgacttgccg cgcgcgaccc
    11101 acgtgaggca catctgttcg cgatccgtca ggtggacgga cggcggaatc gggcggcacg
    11161 tgcgcatgct ctggaactgc agattgaact gcatgccgag caggtacgcg ttgcgccatt
    11221 tcgcatcggc atcgtgcgtc ggcgcggtgc cggacaggct caccagcagc acgcgtccga
    11281 gcggctgatg cagcgggatg ctgatgccgt tgtcgaggcc cgcgtcctcg gcttccatca
    11341 gcagatgccg ctcgcgcagg ttcgccgtcg cgacgtcgtt ccacgagaac ggcgtgctgt
    11401 agcggaatgc cgcgcgatgg acgggatcga tcgcgaagta gtcgttgcgg gtgtagtgct
    11461 cgacccactc ggacggatag tgcagcgaga cgacgtcgat cgacgccgga tgcgatgcgc
    11521 ccgacagctc gacgatcgca tggtgctggt agccgatctg cagcgccgcc tgcctgaaag
    11581 tctcgaccag cgtgcggacg tcgcgcgatt ccggcaacgc ggcggagagc atgggtgtcg
    11641 aagcgctttc tcccgacgac gaccccgcac tgtcatctcc acctgttcga tattcgcgtt
    11701 gaagcagcct gctcaatttg catgcccccg ttattgaaaa tcaagacttt cgaagtgccg
    11761 tgtaccgggt tggggacgcg tcgccaatga aaatcggata acgcaatgac gttgaaattg
    11821 tctgcaaata atatcaaatg caataacgat tgcaagagcg gcgttcggat aatcgagatt
    11881 catttggcga tggcgttcga tatttttatc ccggcgcttc gggtattttt cgctgtctgc
    11941 aacgatccga tcggcaaggc ggcagggcgt ggacagatcg atacggcaat cggtatttta
    12001 aaccgatgct gcgatgcaat aggtaagttc atttcatttt cgagtgagcc aatcttttgc
    12061 gcggatcgcg agtaagtgcc gaatcttcat gcgaaatcgc tgtcagccga ggatggtgtc
    12121 gaatgattat tccgccggat tccgtcttat tagatgtgcg gtaaattctt gtttttcgtc
    12181 gagaaacggc gcgcgaatat attcgtggcg gaacgcgagc cggcgcctgc cgcggctcgg
    12241 cccgaagcgg cgcgcgcggc ggcgcccgct gccgcggtgc cccagcgcgc gcgttcgcaa
    12301 cgtcgcgccg cccggggcgc cgggtacggc gtaggcaacg gaggcgggcg gcggacgtcg
    12361 cgcgtagacg agcgtctcgc gcggcgatcc ggcgcgtctt cagagcgttt cgacgaggtt
    12421 cgccgcgtcg gcgcgcagcg cgacgcgatc gaatttcccg ttcggattgc gcggcagcga
    12481 cgtgcgcgtg gcgatcgtat gcggcaccat gtacggggga agttgctgtg cgcatcgcgc
    12541 gcgcagcgcg tcgggcctga acgtgtcggc gtcgagcggc acgacgacga gcgtgatcga
    12601 ttcgccgagt tcgtcgtgcg gcacgccgag cgcgaccgct tcggccacga acccgctcgc
    12661 gtgcgcgacc tcctcgatct cttccgggct gatccggtag ccggagctct tgatctgcgc
    12721 atcgttgcgg gcgacgaaat agaggaatcc gtcgtcgtcg cggcgcacga gatcaccgga
    12781 ccagacggcc gtctcacgtg gcgcgccgcc cggcttcgcc tcgggcgaag gccggtagcg
    12841 cagcgcggtg cgcgccggat cgttccagta gccgagcgtc acgcacgcgc cgacgtggac
    12901 cagctcgccg acctcgttcg gcgcgcacgg cgcgccgtcc tcgcgcacga cgagaattct
    12961 ggcgttcggc accgccttgc cgatcgaatc ggggcgacgg tcgacttcgg cgggatcgag
    13021 gtaggtcgag cggaacgctt cggtcagccc gtacatcaga tacggcgacg cgctcggaaa
    13081 cagttcgcgc agcgcgtgca gcaccggccg cggcagatgg ccgccggtgt tcgcgaaata
    13141 gcgcagccgc gcgcgcgctt cgccgggcca cgccgcgcgc gcgagctgaa tccagagcgg
    13201 cggtacgccc gcgaagccgg tgatgcgttc gcgcacgcag atctcgacga cgtccgcggg
    13261 catcaggtag ttgacgagca cggcgctcgc gcccgcggcc catgcggtcg tcaactggct
    13321 caagccggcg tcgaagctga gcggcagcgc ggcgagaatg cgatcctgcg cggtatggcg
    13381 caggtattgc gcgacgctcc acgcgccctc gagcagattg cggtggctga gcatcacgcc
    13441 cttggggcgg cccgtcgagc cggacgtgta aaggagtgcg gcgagatcgg cgtcgatcgt
    13501 gtccgctcgc ggctcgggcg cggcgctcgc gtgccggttc gcgacggact cgggcggcgc
    13561 atcgggctgc atccatcgca gaaacgtggt gcgcgaagcc ggcgccggtg caagcgtctt
    13621 cgcatcggtc aggatcacgt acggcatgcc cgcgagcacg ccgtcgccga gtatgcgcgc
    13681 gcgcagcgac gacgtgacga gacagcgcgc gccgctgtcg acgaggatgt gatgaacctg
    13741 ttcgggcttg agggccgggt tgatcggcac gaacacgacg ccggccgccg cggcgccgag
    13801 catggcgacg accgtctcga tgcgcttgtc gagaaagatc gcgagccgct cgccctgggc
    13861 gatctcgagc gcttgcagcc gctcggcgaa cgccaggccg agcgccgcga gtgcgcgata
    13921 ggtgagccga gcgtcgccgg cgacgagcgc ctcggcatcg ggcgtgcggc atgccgcctg
    13981 ttcgaccaga tcgaagaaat tacgcatgat tccacctccg ttttgaaact cgggcggcgc
    14041 acgtcgagcg atgcggcgaa gctcgcgatg gctaacgacc gtcgcgcgaa cgcggccgat
    14101 cctggctgcc gaaagagtag cgaatggaca cggcgcgcgg tcgcggcgca tcgatgtaaa
    14161 tggccgaacg gggtggtgcc gaacattgac ggatgcggcc gcgcgccgcg ctagcacatt
    14221 cgacatgcac gcgcgcgcgc atggaggaga tcgtctgctc gacgtgatcg tcaattgtcc
    14281 tgatgaattt cgccggcgcg ctcggacacg gtctttcaat tcggttgcat gtgtcgcgcg
    14341 ggcgaacgca tcgcatgtcg agcggcacgc gccgaggcga gctcgcatcg cctgcaagga
    14401 accggtgtcg cgccgcgtct ttccatggaa gcgcgagatg cacgcttcgc ggcgaatgga
    14461 tgtgtgcgca accattgcga ttcgttccgg cggccgtgcg ccgcacgcgt gcgtgcgcgt
    14521 gcgcatgcgt cggccggcgc ggcgtccgat ggcgggctgc cggtgcgcgc gcggtgcgcg
    14581 cgcgccagcg cgagcgccgg cgtcacggcg cgtcgtggaa gatgatcccg agcgtatggc
    14641 gctgcccgga gcgcacgcgg ctcacgccgt gccgaagatt cacgcgatag acaccgcgcg
    14701 cgccttgcac cgggcgatga tggacggcga acacgaccgc gtcgccctgc tcgagcggca
    14761 cgacatcggc gcgcgattgc atgcgcggcc gttgctcggt gatcacgaat tcgccgcccg
    14821 cgaaatcggc gcccggcttc gacagcagaa ccgccgcctg cagcgggaat acgtgctcgc
    14881 catacagatc ctgatgcagg cagttgtagt cgccttcgcg atagcgcagc agcagcggtg
    14941 tcggacgcag ttgtccggct gcgcggcaac gctcgatgaa gtgcgcgtgc tcggcgggaa
    15001 accgcgcgtc gatgcgcatc tgcgcatgcc agcggttcgc gatcggcgcg aggtgcgggt
    15061 acagcgcggt gcgcagcgcg tggaccatgc gcggcagcgg gtagccgaaa tactggtatt
    15121 cgccgcggcc gaacccgtgg cgtgccatcg tcacgcgact gcggaacagc gcgtcgcgcg
    15181 cgtagagcgc ggcgagcgct tcgcacgtgc gcggcgcgag cagcccatgc acgatcgcat
    15241 ggccgtcgcg ctcgagatcc tgttcgatcg acgcccacgg caacgcgtcg atccgccgcg
    15301 cgagcgcggc ttcgcgcgcc gcgccgctcg ccgtttcatc gtgcgcgcgg gcggccggca
    15361 cgcgtggttc ggacaacgta ttcatcggcg cttcctcgcg gcatcgtggg ggatcgaggc
    15421 ggccagtcta gcggggcggg cgaagcgatg cacaccggat cttgcgctgc aattcggccg
    15481 cgcattatgt ttcgcgcgat gtctcgcgcg cgggccgtca cgccgccatg cgcgtcaggt
    15541 cagcgcgtgg aaagcccaat agagcgcgcc cgcgagcacg atcgacgcgg gcagcgtcaa
    15601 cacccacgcg agcacgaggc tgcgcaccgt gctccattgc agcccggagc cgttcgcggc
    15661 catcgtgccc gcgacgccgg aagacagcac gtgcgtcgtc gacaccggca gcccgtacgc
    15721 atcggccgcg ccgatcgtga gcatcgcgac gacttccgcc gacgcgcctt gcccgtaggt
    15781 cagatgctgc ttgccgatct tctcgccgac ggtcacgacg atgcgccgcc agccgaccat
    15841 cgtgccgagg ccgagcgcga tcgccaccgc gaccttcacc caggtcggaa tgaatttggt
    15901 cgcgtggtcg agctgcctgc ggtagtcgtc gagcgcgagg cgatccgccg gcgagaacgc
    15961 cggccggccg gttttctcca tcaggcgcag ggcttcggac accagataca tcgtgttgcg
    16021 cacgttgtcc gcctgcccct cgggcacttt cgcgatcgag cccgtcgcgc cgacttcggc
    16081 cgcgagcgcg tccgacaacc ggcgaaccgc gggcagcgtc gcgtcgctca ggcggcgcga
    16141 ctgcacgtaa gcctcgacat cggcgcgcgg gttcggcgac ggctgcgcgg cgcccgcgta
    16201 gcgggcgagc gtttcggacg cgcggtgtgc gacggcgatg aacgtttgtg tctcgccggg
    16261 cgtgaccgcc ttgttgagcg cgtatgcggt cggcacggtg ccgatcagga tcagcatgat
    16321 gagccccgtg cctttctgcc cgtcgttcga gccgtgcgcg aacgacacgc cggtgcaggt
    16381 caggatcagc aggcagcgga cccagaacgg cggcggctcg ttcgtctgcg gctcgcggta
    16441 gagcgcgggc acgcgcacga gcgccttcag cgcggcgagc agcagggccg cgcacaggaa
    16501 gccgacgagc ggcgagagca gcagcgattg gccgacgccc gccgcctgcg cccaatcgac
    16561 gccgctcgtg ccggacggcc cgtgcatcag ctgattcgcg agcccgacgc cgatgatcga
    16621 gccgatcagc gtgtgcgagc tcgacgaagg caggccgaag taccaggtcg cgagattcca
    16681 cgcgatcgcc gcgatcagca gcgcgaacac catcgcgaag cccgcgccgt ggccgacttg
    16741 caggatcagc tcgacgggca gcagttgcag gatgccgaac gcgaccgcgc ccgtcgacgc
    16801 catcacgccg agaaaattcc agatgcccga ccagatgacc gcgacgttcg gcgtcagcga
    16861 atgcgtgtag atcacggtcg ccacggcgtt cgcggtgtcg tggaagccgt tgacgaactc
    16921 gaagccgagc gcgatcgcga gcgcgacgcc gagcagcaga tacggaaacg ccgagcgtgg
    16981 gccgacgggc gcgagatccg cgaacaggtg aacgaacacg tacgcgacgc cggcggcgag
    17041 gagggcgacg agcagcgcga cgcccagatg ccgggtgcga ccgagctctt cgctcgccgc
    17101 ggcggacaga aggggattca tgacggccct tgtttggaac ggatcgttcg atcctagccc
    17161 tcgcgatcag gcagtttgat gacagcgcgc aaaggggggg cgattcgggt gtgcgactcg
    17221 gaggcgtcgg tcatgggcgc gtcgcgggcg cgggattcgg ggacgcgatt gggccgcgca
    17281 agattgggcc gcgcaattct gtcgcgcggc tcggccacgc ggttcggcgc cgcgattcat
    17341 cgctgcgatg catggccgcg gttcggaatt gcgatgcgaa accgcgctcc gcggctacgg
    17401 tctgggcgcg cttcgagacc gcgattcggc gcccgaattc ggcgctccgg ttcggcggcg
    17461 gcgcggcggg cgcacgccgc gcatgcgcgc ggcgcgcgct cagccgtcga tcgcctgctc
    17521 gatgcgcgcg agcaccgaag gccagccgcg cttcattcca tcgtaggcaa tgcgcgcctg
    17581 cggcgcgtcg agatcgaagc ccgcgtgctc gaagcacacc cgcgtgccgc cgggcgcggg
    17641 ctcgagccgc catgtgatcg tcgtgtcgag cgtgcgttgc gcgaacgcga tcgcgaaccg
    17701 gcgttcgggt tcgaccgcga tcacttcgca cggctgccgg ccccacgggc ccatgtcgag
    17761 cgtgaaacgg tggccgggga cggggcgtac gtcgcccgcc gcccaccagc gcgcgagcgc
    17821 cgcgggggtg gtgagcgccg cccagacctg cgcaggcggg cgggcgacga attgctcgag
    17881 gcggatcggt tcggcttcgg tcatcgcgtc ggattcgaga aagcgcgtgg cggaatgcgc
    17941 atgatagggg atgccgcccc cggacgatac ggctcgtcgg cgcgacgcgt tgcccgcgga
    18001 gcgcgggatg cgcgggggca cggagggcgc gaaggcgcgc aggcgcagag ggcgcagagg
    18061 gcgcagaggg cgcagagggc gcagagggcg cggaggacgc ggaggacaca gggccggccg
    18121 cagccggccc acccacgcca tgggcagccg cggatgcggc gacggagccg ttcgcggcgt
    18181 cgttcacgga atcggcagtt cggcctcgcg tttcacctcg cgcagcgaca gcgccgattc
    18241 gatcgacgtg acgccgggca gcacgcgcag cgtctcgcgc aggaacgtgc cgtagtcgtc
    18301 gagatcgtgc gcgaccactt gcagcagata gtcggcggac cccgacacgt tgtggcacga
    18361 caggatgcgc ggaatgccga gcacctcgcg ctcgaagcgg ttcgcgacgc tgcgatcgtg
    18421 aaccgagcag cgcagcagca cgaacgcgac gacgccgaag ccaagcgcgt tgcgcgagag
    18481 ctgcgcgcga tagcgttcga tgtagccgtc gctttcgagg cgtttgagcc gacgcgcgca
    18541 cggcgtttcg ctcaggccca ccgaatcggc gaggcgggcg accgggatgc ggccgtcgag
    18601 ctgcactgcg gcgagaatgg cgcggtcggt tttgtcgagt tcgatcatgt tgtgggaaag
    18661 ctctaagaaa tcggtttcta ttagtgtatt ccaatcagtt tggtgcatcg gtcggccaaa
    18721 ttagccaaaa agcgctcgtc gagcgggtgc aacatggagc cctttccact cgggttcgat
    18781 catgttttcc gctcatctgc tgctcgtcta cgtcgccgcc gtcgtggccg tctatgccgt
    18841 gcccggcccc gacatggcgt tcgtgctgca gacgggcatc ggccgcggcg cgcggcacgg
    18901 cgcggccgcc gccgcggggc tcgggctcgc gcgcgccgtg cacgtgacgt tgtccgcatg
    18961 cggcgtcgcc gcgctcttga agagcgcgcc gtggctctac gaggccgtgc gctacggcgg
    19021 cgcgctgtac ctcgcgtacg tcgcggtgca gatcttccgc tcgccggcgt tcgcgctgtc
    19081 cgccgccgac gcggccgcgc ccgccgcccg gctgcgccat accttcgtca agggcctcct
    19141 caccaatctg ctcaacccga aggcgctgct gttctgctcg gtgctgctgc cgcagttcgt
    19201 ccagcggggc ggcgcgccgg tgatcgcgca gatggcggtg ctcggcgcgg tgctcgtgct
    19261 cgcgggcctg tgcttcgatc tcgcgtgcgt cgccggcgcg acgcgcatcg ccgaatggtt
    19321 gcgcgcgcat ccgcttgcgc aactcgccca gcgctggacg ttttccgccg tgctgctcgg
    19381 cttcgcgctg cggctgtcga tcgactgatt ccgatcgacc ccggaccgcc ccggtcggcg
    19441 gatgcggcgc gcacgagcgc gggcggcggc gaagcgcggc gcgcggagcg aatcgcgggg
    19501 cacgcgaggc aaccaatcgg caaccaatcg cgaaacgcgc gccatcgccc gcgatcgcgt
    19561 cgacgcggcg cgccgaacgt cgcgaacggg cggcgcaagc gcgcgagatg cgcacgcagg
    19621 attgccgcgc gtgctttaca cttgctttgc cgtactgtcg cacgctcccc atggcggcgt
    19681 gtgtgcgccg tccgacatac cgcccggaac tgcgatcgcg cgaccgtgtc cgaatcctgg
    19741 caatccgtca ccacggcttc tggagggtcc gaatatggca aggcatcttc acgccggcaa
    19801 cgaatcgcat ctcgtcgccg aatccacgtg catcgggccg tgcgatccgg ccgagacgat
    19861 tcatgtagtg gtgatgttgc ggcgacagca agagcagcac ctcgattcat tgttgcaggg
    19921 cctcgcgagc ggcgatccgg gcgtgaagcc tgtctcgcgc gaggcgttcg cccagcgttt
    19981 cggcgcgcat cccgacgacg tcatgaaagt cgaggcattc gcgcagcagc gcggcctcgc
    20041 ggtcgcgcgc gtcgatccgg tcgagagcct cgtcgtgctg tcgggcacga tcgcgcagtt
    20101 cgaggcggcc ttcggcgtga agctcgagcg cttcgagcat cggtcgatcg gccagtatcg
    20161 cggccgcacg ggcgatatca cgctgcccga cgagttgcac ggcatcgtca ccgcggtgct
    20221 cgggctcgac gatcgcccgc aggcccggcc gcatttccgg ctgcggccga cttttctgcc
    20281 cgcgcgcgcg ccggccgtca cctacacgcc gccgcagctc gcggccctct acgatttccc
    20341 gcccggcgac ggcgcgggcc agtgcatcgc gatcgtcgag ctcggcggcg gctatcggcc
    20401 ggccgagatc cagcagtatt tcggcggcct cgggctcgcg cggcagccga agctcgtcga
    20461 cgtgagcgtc ggcgcggggc gcaacgcgcc gacgggcgat ccgagcgggc cggacggcga
    20521 agtcgcgctc gatatcgaga tcgcgggcgc gatcgcgccc ggcgcgacga ttgccgtcta
    20581 tttcgcgcag aacagcgacg ccggcttca
//
