LOCUS       NZ_CP009162            20843 bp    DNA     circular CON 03-FEB-2024
DEFINITION  Burkholderia pseudomallei K42 chromosome 1, complete sequence.
ACCESSION   NZ_CP009162
VERSION     NZ_CP009162.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei K42
  ORGANISM  Burkholderia pseudomallei K42
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3969389)
  AUTHORS   Johnson,S.L., Baker,A.L., Chain,P.S., Currie,B.J., Daligault,H.E.,
            Davenport,K.W., Davis,C.B., Inglis,T.J., Kaestli,M., Koren,S.,
            Mayo,M., Merritt,A.J., Price,E.P., Sarovich,D.S., Warner,J. and
            Rosovitz,M.J.
  TITLE     Whole-Genome Sequences of 80 Environmental and Clinical Isolates of
            Burkholderia pseudomallei
  JOURNAL   Genome Announc 3 (1), e01282-14 (2015)
   PUBMED   25676747
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3969389)
  AUTHORS   Baker,A.L., Bunnell,A., Chain,P.S., Chertkov,O., Daligault,H.E.,
            Davenport,K.W., Davis,C., Gleasner,C.D., Johnson,S.L., Koren,S.,
            Kunde,Y.A., Mayo,M., McMurry,K.K., Robison,R., Rosovitz,M.J. and
            Warner,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-AUG-2013
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; Allpaths v.
            44837; Phrap v. SPS - 4.24; Hgap v. 1.4
            Genome Coverage                   :: 415x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/03/2024 03:30:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,503
            CDSs (total)                      :: 6,427
            Genes (coding)                    :: 6,257
            CDSs (with protein)               :: 6,257
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 99 of 170
            Pseudo Genes (incomplete)         :: 105 of 170
            Pseudo Genes (internal stop)      :: 19 of 170
            Pseudo Genes (multiple problems)  :: 47 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:06:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3490542
            Orig. end                         :: 3511385
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009162.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The DNA was obtained from Dr. Richard Robison, Brigham Young
            University (BYU), richard_robison@byu.edu.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20843
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20843
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20843
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10843](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10843)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(497..512)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.67"
                     /tool="antismash"
     misc_feature    1242..1255
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.19"
                     /tool="antismash"
     misc_feature    complement(1245..1258)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            1296..2006
                     /gene="ispD"
                     /locus_tag="X993_RS15760"
                     /old_locus_tag="X993_3084"
     CDS             1296..2006
                     /EC_number="2.7.7.60"
                     /GO_function="GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006402218.1"
                     /locus_tag="X993_RS15760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3084"
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="WP_043313590.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.5e-12, bitscore:
                     43.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSRLFALIPCAGTGSRSGSALPKQYRTLAGRALLYYTLAAFDAC
                     SEFAQTLVVISPDDAHFDARRFAGLRFAVRRCGGASRQASVMNGLIQLAEFGATDADWV
                     LVHDAARPGITPALIRTLIGALKDDPVGGIVALPVADTLKRVPAGGDAIERTESRNGLW
                     QAQTPQMFRIGMLRDAIRRAQLDGHDLTDEASAIEWAGHTPRVVQGSLRNFKVTYPEDF
                     DLAEAILAQPARAS"
     misc_feature    1301..1316
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.74"
                     /tool="antismash"
     gene            2047..2535
                     /gene="ispF"
                     /locus_tag="X993_RS15765"
                     /old_locus_tag="X993_3085"
     CDS             2047..2535
                     /EC_number="4.6.1.12"
                     /GO_function="GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010104424.1"
                     /locus_tag="X993_RS15765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3085"
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="WP_004191369.1"
                     /transl_table=11
                     /translation="MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHA
                     ITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQA
                     PKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA"
     gene            complement(2904..3431)
                     /locus_tag="X993_RS15770"
                     /old_locus_tag="X993_3086"
     CDS             complement(2904..3431)
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004193734.1"
                     /locus_tag="X993_RS15770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3086"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_004193734.1"
                     /transl_table=11
                     /translation="MEFIESIKAQIPDYAKDIRLNLDGTISRSSLEGTDAVGAALAAAF
                     AAKSPVLVKAIREAGVLSPEETQAALTAAALMGMNNAWYPYVEMADDADLKTQRAELRM
                     GAYATHGGVDKRKFEMYALAASIVGKCHFCVKSHYALLKNEQGMTVTQLRDVGRIAAVI
                     NAAAQVISAEGK"
     gene            complement(3509..4057)
                     /locus_tag="X993_RS15775"
                     /old_locus_tag="X993_3087"
     CDS             complement(3509..4057)
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004192241.1"
                     /locus_tag="X993_RS15775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3087"
                     /product="peroxiredoxin"
                     /protein_id="WP_004192241.1"
                     /transl_table=11
                     /translation="MKTVGDKLEAFTVVAAKPGFNNHEENGQSAFETVTEASFPGKWKI
                     IYFYPKDFTFVCPTEIVEFAKLAKQFEERDAVLLGGSSDNEFVKLAWRREHKDLDKLNH
                     YSFGDVKGELIDQLGVRDKEAGVALRATFIVDPDNTIQHVSVNNLNVGRSPEEILRILD
                     GLQTDELCPCNRAIGGATL"
     misc_feature    complement(4156..4171)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     misc_feature    complement(4158..4174)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.15"
                     /tool="antismash"
     misc_feature    4158..4174
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.37"
                     /tool="antismash"
     misc_feature    4163..4176
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.09"
                     /tool="antismash"
     misc_feature    4206..4220
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(4255..5613)
                     /locus_tag="X993_RS15780"
                     /old_locus_tag="X993_3088"
     CDS             complement(4255..5613)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012364087.1"
                     /locus_tag="X993_RS15780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3088"
                     /product="ATP-binding protein"
                     /protein_id="WP_004531418.1"
                     /transl_table=11
                     /translation="MRIDRRLLTLVFGGLFWRTFLLIALLIAVSLAAWFQSFRVIEREP
                     RAQRVALQLVAIVKLTRTALLYSDPDLRRALLQDLESNEGVRVYPREKTDKFKLQPDES
                     VNRLIEHDIRSRLGDDTVIAQSVNDIPGVWISFKIDDDDYWVALDRDQLDTVTGLQWAG
                     WGLFALALSLIGSAFITSLVNQPFSRLALAARKVGSGQTPEPLPERGMGVAAETNRSFN
                     QMVRDLEQLEADRALMLAGISHDLRTPLARLRLETEMSPSDQATKDAMVDDIEQMDRII
                     AAFIDYARPAQRTPEPVDLSQVAREVAARIVSEDGVQLDIRLAPAAVIEADETDMRRVI
                     GNLVENARKYGQSKQDGIARILLETRVTHARVELVVADEGPGIPEDQLPLVMRPFYRVD
                     TARSKADGTGLGMAIVLRLVNRYRGALRLRNRTPDAGLEVTLEFPSAKARAAA"
     misc_feature    5608..5628
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.11"
                     /tool="antismash"
     misc_feature    5662..5682
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(5668..5682)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.67"
                     /tool="antismash"
     gene            complement(5680..6405)
                     /gene="ompR"
                     /locus_tag="X993_RS15785"
                     /old_locus_tag="X993_3089"
     CDS             complement(5680..6405)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="ompR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009517537.1"
                     /locus_tag="X993_RS15785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3089"
                     /product="two-component system response regulator OmpR"
                     /protein_id="WP_004199523.1"
                     /transl_table=11
                     /translation="METKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENATAMNKL
                     WVRERFDLLVLDLMLPGEDGLSICRRLRGSNDRTPIIMLTAKGEDVDRIVGLEMGADDY
                     LPKPFNPRELVARIHAVLRRQAPAELPGAPSETTEVFEFGEFSLNLATRTLTKSGQEIP
                     LTTGEFSVLKVFARHPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSP
                     RFIQTVWGLGYVFIPDGAA"
     gene            6493..6675
                     /locus_tag="X993_RS34775"
     CDS             6493..6675
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004192596.1"
                     /locus_tag="X993_RS34775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004192596.1"
                     /transl_table=11
                     /translation="MRSKDSHDRLLYSKTTFGGYSIHLTFTWFARPILAGFVRVPKVAG
                     CRVTKGTKRRKRRGP"
     misc_feature    6562..6564
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6675..6965
                     /locus_tag="X993_RS15790"
                     /old_locus_tag="X993_3090"
     CDS             6675..6965
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006026135.1"
                     /locus_tag="X993_RS15790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3090"
                     /product="hypothetical protein"
                     /protein_id="WP_004554303.1"
                     /transl_table=11
                     /translation="MRPTKMAFVLAFACAGFLASDFACAQRPERGAPPSHKVPRGNGAA
                     RRPAPPGEPPARAAAVPPDLEQRRRDGHMTPEERHLLRQHIEDAVRELYKR"
     gene            7209..8624
                     /locus_tag="X993_RS15795"
                     /old_locus_tag="X993_3091"
     CDS             7209..8624
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009980659.1"
                     /locus_tag="X993_RS15795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3091"
                     /product="DUF1800 domain-containing protein"
                     /protein_id="WP_038761385.1"
                     /transl_table=11
                     /translation="MPAAMQTLLDADDARFLLTRTGFSPPPRALARFVGMTRAQALAEL
                     LDGARTQSVTSPPDWVREPPPSRAMRAAFSPDERRAEQQLRNRRYDELRAWWVREMIVT
                     PSPLTERMTLFWHNHFTSGQDKVPFPQTIAAQHALLRANALGNFGAMLHGVAKDPAMLQ
                     YLDGASNRKGRPNENFAREAMELFTLGEGHYTQRDVFEAARAYTGWGLDPDALTYVFRP
                     NVHDDGVKTVLGETGRFDGDAVLDILLGRPETARFVVAKLWREFVSDAPDAGEVERIAA
                     RLRQSDYDIRAALTELFSSDAFWAERNRGVLVKSPAEFVVGTVRLFDVDYVDAAPFANT
                     LRALGQNLFYPPNVKGWPGGVSWINSATLLARKQFVEQMMRATEAPGMRAAPVSRDMAG
                     QPAPTRRGAMRFDLDAWLAAYRTKPQAQPDLSTELQLQHAVLPISPVAAIEAGATSGAY
                     LQALLMDPAYQLK"
     gene            8707..9960
                     /locus_tag="X993_RS15800"
                     /old_locus_tag="X993_3092"
     CDS             8707..9960
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004550279.1"
                     /locus_tag="X993_RS15800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3092"
                     /product="DUF1501 domain-containing protein"
                     /protein_id="WP_038731327.1"
                     /transl_table=11
                     /translation="MKRRDFLALASLAGAAGVSLPVPYAFAAAPGETSATGAMGAVGAA
                     RAARYSNLLILVELKGGNDGLNTVIPYANPLYRTLRPAIGVKREQVVQLDERAALHPAL
                     EPLMPIWRDGRLAIVEGVGYPQPNLSHFRSIEIWDTASRANEYLREGWLTRAFAQASVP
                     PGFAADGIVLGSAEMGPLANGARAIALVNPAQFARAARLAQPVSLRERNPALAHVIDIE
                     NDIVKAADRLRPHAGTPALATAFPGGPFGASVKTAMQVLAACDTPQRTPAPGQGVAVLR
                     LTLNGFDTHQNQPGQQAGLLGQLAQGLVAMRSALIELGRWNNTLVMTYAEFGRRARENQ
                     SNGTDHGTAAPHFVMGGRVRGGLYGAPPALDALDGNGNLPVAVDFRQLYATVLGPWWGL
                     DAASVLRQRFEPLPLLRA"
     gene            complement(10001..10843)
                     /gene="hpnD"
                     /locus_tag="X993_RS15805"
                     /old_locus_tag="X993_3093"
     CDS             complement(10001..10843)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009980658.1"
                     /locus_tag="X993_RS15805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3093"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_004554306.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.6e-37, bitscore:
                     124.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.1e-34,
                     bitscore: 115.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFDEYCQQKAAPPGSSFYYALRQAPLARQPLVAALFALRRELEQ
                     TVKEVSDPTVGHTKLAWWQKELAALASGHPSHPVSQALAAHHPDIARETDALRTLVAGY
                     GMDLEQARYLDFANLRRYADQTGGMFAALVASASASAGRPTANGARWAQPLGQALTLAQ
                     FVQDLGQDARQGRIYVPIDELQRYGVTAADLLNRRYSPAYTELMRFQTSRARDALNASL
                     SGIPADERRAQRTLRALGALALAVLDEIERDGFQVLHQRIALTPIRKLWIAWRAARRR"
     tRNA            11073..11159
                     /anticodon=(pos:3501649..3501651,aa:Leu,seq:tag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="X993_RS15810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="X993_3094"
                     /product="tRNA-Leu"
     gene            11073..11159
                     /locus_tag="X993_RS15810"
                     /old_locus_tag="X993_3094"
     misc_feature    11220..11229
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.64"
                     /tool="antismash"
     gene            <11438..11832
                     /locus_tag="X993_RS43170"
                     /pseudo=""
     CDS             <11438..11832
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006408937.1"
                     /locus_tag="X993_RS43170"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DNA adenine methylase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ELSAAHISHIRLANAYIERFDWATSIDRCDRPYALFYLDPPYFET
                     EGYGVAFPFAEYEKIAERLRSIKGAGDRQPQ"
     gene            complement(11853..12575)
                     /locus_tag="X993_RS15815"
                     /old_locus_tag="X993_3096"
     CDS             complement(11853..12575)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009920998.1"
                     /locus_tag="X993_RS15815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3096"
                     /product="immunity 52 family protein"
                     /protein_id="WP_011205127.1"
                     /transl_table=11
                     /translation="MEIKAMFRDVSLSSRNFSEMLSRESKVVAALAAKSPLMAHANWRL
                     KGNSLEEATLYPAFDADGSPSTPALAVLNEEQRGKKHSASHAAIWNGNTRPNEGASMSC
                     HVSDEKVLPDRFSTRLGVPDCYAKSQDLADVVTTIVAAFNPLVVEASPEGYFDKQVFDD
                     KPGVGWMLYLPKVITQQQVPEARALIPVSAKGKQTGTIIVSVTDAPFSVDNPEHVAIAN
                     RIEIRLVDQDLLPAYVDI"
     misc_feature    complement(12240..12242)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12357..12359)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12582..13175)
                     /locus_tag="X993_RS15820"
                     /old_locus_tag="X993_3097"
     CDS             complement(12582..13175)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004521246.1"
                     /locus_tag="X993_RS15820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3097"
                     /product="restriction endonuclease fold toxin 5
                     domain-containing protein"
                     /protein_id="WP_226812948.1"
                     /transl_table=11
                     /translation="MVVPIVEAAAVELGPILARVGVALLGGATVAGTASLSGDTPKEDS
                     KATPDVRALPRTGESCKKCPPDAGTRIRRNHGVNWNSYRYQARITGFPFDTEACRWSEE
                     WRWLEVDFDGFQPGECMLQETKGNYDQFLDGSIPGAEDFFKGFDSMETQITNQATRVRA
                     NPPARLTWYFQTQLTKRKMTPLLSSLGVRSVYQP"
     gene            complement(13060..13533)
                     /locus_tag="X993_RS15825"
                     /old_locus_tag="X993_3098"
     CDS             complement(13060..13533)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009982284.1"
                     /locus_tag="X993_RS15825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3098"
                     /product="hypothetical protein"
                     /protein_id="WP_038759449.1"
                     /transl_table=11
                     /translation="MLELSAEQVAGLAQIDERGFVERVRQDLVKENPAFADDGGLSSRL
                     WTAYRAARTFGIERDENIVAFLRLEAYAPGFYEKPATKAWLTRPGRSADARFHDYLRVI
                     KWRIEHPDGGLEHGGIGGANRGSGGGGAWADLGARWRRLAGRRDGGGNGESVG"
     gene            complement(13526..14032)
                     /locus_tag="X993_RS15830"
                     /old_locus_tag="X993_3099"
     CDS             complement(13526..14032)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004539879.1"
                     /locus_tag="X993_RS15830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3099"
                     /product="DUF4123 domain-containing protein"
                     /protein_id="WP_004552779.1"
                     /transl_table=11
                     /translation="MMTPPNIEAHFEMRRQQITLPARLFAVVDALLFAEASDAPALRRA
                     NYSIALFDRTPDASLADHGPWLIDYAIAPGPIRRVLAELAAGPVGMSWLISAYPFERLA
                     AELREHLDVRLPDGRTALFRFYDARIMPDIARVMSDAQRSQFFVATYDWLVEIDGRLTG
                     VHPHA"
     gene            complement(14029..14454)
                     /locus_tag="X993_RS15835"
                     /old_locus_tag="X993_3100"
     CDS             complement(14029..14454)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004538209.1"
                     /locus_tag="X993_RS15835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3100"
                     /product="PAAR domain-containing protein"
                     /protein_id="WP_038754499.1"
                     /transl_table=11
                     /translation="MAKRAIICVGDTTTHGGKVLEGAPTFTLNGRNVAGVGHQVLCPRC
                     KGIFPILPDLLGRRYPHTIGERDTAVEGMRTACGAELIASQGTGTIDDVGAGERGDGGS
                     PGGSAAVAAAAVAPFPTLCLECLKAAAKNAATMVARG"
     gene            complement(14735..15130)
                     /locus_tag="X993_RS15840"
                     /old_locus_tag="X993_3101"
     CDS             complement(14735..15130)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004557051.1"
                     /locus_tag="X993_RS15840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3101"
                     /product="hypothetical protein"
                     /protein_id="WP_038754502.1"
                     /transl_table=11
                     /translation="MELKMGKANTIELTNNTSFTLVLHTIYANTGNWSGDYPPAYLRPN
                     DTLIFTSTLDGKGDLNGSARFDILDTAVKRCPDATYVQLNWDNPVGADNGGSSSVVGTT
                     AQFFNVSGPTISGDYGHPTFSWSVNGA"
     misc_feature    complement(15005..15007)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15122..15124)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15318..15332)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.5"
                     /tool="antismash"
     gene            <15420..15608
                     /locus_tag="X993_RS42100"
                     /pseudo=""
     CDS             <15420..15608
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890252.1"
                     /locus_tag="X993_RS42100"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LRSLEGRAIVSLHDHPEIRHLFIGFDIESVSIRYTAGGGKGGERR
                     ELIIFNWDDAAEPAGLF"
     misc_feature    complement(15454..15467)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            complement(15644..15877)
                     /locus_tag="X993_RS15845"
                     /old_locus_tag="X993_3102"
     CDS             complement(15644..15877)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004527234.1"
                     /locus_tag="X993_RS15845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3102"
                     /product="Imm52 family immunity protein"
                     /protein_id="WP_004527234.1"
                     /transl_table=11
                     /translation="MLNAVTSTARFALTQQQVPEAHALITVPEAGKRLTGTIVVSITDA
                     PFSLDNPEHVAIANRIEIRLVDQDLLPAYVDI"
     misc_feature    complement(15885..15897)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     misc_feature    15943..15952
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            complement(15953..16414)
                     /locus_tag="X993_RS34795"
                     /old_locus_tag="X993_3103"
     CDS             complement(15953..16414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011851784.1"
                     /locus_tag="X993_RS34795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3103"
                     /product="avidin/streptavidin family protein"
                     /protein_id="WP_004550288.1"
                     /transl_table=11
                     /translation="MKKTLVSLAMLGAFAQPAWADTSTAPNCQNPIGSWLNELGSTMTI
                     ASISGTGAITGTYVSPSGTTGQTFSLSGWFYAAPPANNGLDQVTLVTFSVNWNNTAARY
                     NSITTWSGLCQITNNVPTITALYYYSNAFAQYSWKHVNVGQDIFHPIAP"
     misc_feature    16405..16419
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.7"
                     /tool="antismash"
     misc_feature    16520..16536
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.87"
                     /tool="antismash"
     misc_feature    complement(16609..16623)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.34"
                     /tool="antismash"
     misc_feature    complement(16699..16714)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.91"
                     /tool="antismash"
     misc_feature    complement(16807..16821)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.68"
                     /tool="antismash"
     misc_feature    complement(16930..16945)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.02"
                     /tool="antismash"
     misc_feature    complement(17197..17210)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.14"
                     /tool="antismash"
     misc_feature    17204..17220
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.24"
                     /tool="antismash"
     misc_feature    17278..17291
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            17351..17533
                     /locus_tag="X993_RS40850"
     CDS             17351..17533
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004193710.1"
                     /locus_tag="X993_RS40850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004193710.1"
                     /transl_table=11
                     /translation="MKFELPISGTYARSRRAERTMTKHVDREAQMPLLAEKKALPASLR
                     RLSSCMPTYRARLPE"
     gene            complement(17660..18283)
                     /locus_tag="X993_RS15855"
                     /old_locus_tag="X993_3104"
     CDS             complement(17660..18283)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009980362.1"
                     /locus_tag="X993_RS15855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3104"
                     /product="phospholipase D family protein"
                     /protein_id="WP_009980362.1"
                     /transl_table=11
                     /translation="MQLPKRFAAACLATAFLCGAPPAVSKTTSESLLERLVALIADALP
                     SSAKQAPAGQVVEAAFSPDGGAEALVLKVIGTSRASLRLAGYSFTSPKVVRALLDAHRR
                     GVDVAIVVDNDGNRSKASKQALNLLVNAKVPTRTIDRYAIHHDKYIVVDGRHVETGSFN
                     YSAAAAARNSENVLVVWNNPALAAQYLKHWQNRFDQGTAYRSAY"
     gene            complement(18478..19587)
                     /locus_tag="X993_RS15860"
                     /old_locus_tag="X993_3105"
     CDS             complement(18478..19587)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011851783.1"
                     /locus_tag="X993_RS15860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3105"
                     /product="class II histone deacetylase"
                     /protein_id="WP_004554310.1"
                     /transl_table=11
                     /translation="MTKTAFFTDERTFWHTGGAHALFFPVGGWVQPPSSAGYAESPDSK
                     RRLLSLVHASGLAAKLDMSSAPAATDDDLRRIHPAHYLDAFKRASDAGGGDLGELAPFG
                     RGSYEIAALSAGLALAAVDAVLAERTANAFSLSRPPGHHCLRDKPMGFCLLANIPIAIE
                     AARAKHRVERVAVIDWDVHHGNGTQSIYYDDPNTLTISLHQDRCFPPGYSGADERGAGA
                     GAGANVNVPLLAGAGDDAYRYAFERIVLPALDAFRPELVIVASGLDANAVDPLARMQLH
                     SDSYRYMTHALKQAAQRHCGGRLVIVHEGGYSEAYVPFCGHAIVEALAGMRTDVADPML
                     ELAIAQQPGERFNAFQRQLIDEMATSFGY"
     gene            complement(19644..20837)
                     /locus_tag="X993_RS15865"
                     /old_locus_tag="X993_3106"
     CDS             complement(19644..20837)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011851782.1"
                     /locus_tag="X993_RS15865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="X993_3106"
                     /product="MFS transporter"
                     /protein_id="WP_038760448.1"
                     /transl_table=11
                     /translation="MTIKTLRQEPALAGAASPADTPAFTSGTLAALVAFAAITPLLLLV
                     APAVAGQLGAQLGLSASRIGTYFFVELGAFSAATLPSYLWLGRIDARRIAWGATAVFCA
                     GNLATAVWMPGFAPLLALRAATALGGGTLMVLCMTSAAASGNSDRVYGLWVVGQLIAGA
                     AGLFLLPHLFDMVGLRALYAVLAALALCAAPLARRFPAVPRGRAQHAPRARAQAARMAA
                     ALAIGGVLTFYVAIGGVWTFASKAAAAVGLDAQTSGNVLAIASLMGIAGAALASYLGGR
                     AARRAMLLAGYGILAASLVALAAAPNANGYTLAIFGFKFAWTFVLPFMLASVAALDATG
                     RLIATLNLVIGSGLAAGPLAAGLMLDGGGTLRALFSIATAVSLVSLAAMLRVEHDAR"
ORIGIN
        1 gcccgccgat tcgacggtga aaagcacgcg gttcttcgtc gtttcgagat acgcggcgaa
       61 cgcggcgagc ggcgcgtccg cgtggcgctc gagcgcgaga ttcggcagcg gcgcggccca
      121 gccgcccgac ggctgcgcgg gcagcacgat ccgcgcgaac ggcttggcga gcaggtagaa
      181 atcgtcgtcg gagaggaaca ggcgctgcgg ctcgaggatc ggccgctcgc gatcgtgcga
      241 caggaacgcg tggcgctgct tcgtgtcggc ggtgaagcgc ttgatcgccg cgtcgagatc
      301 gcccgtgaac acgagctgcg cgcgctcggg cagatagtgg aagagcgtcg ccgtctcgtc
      361 gaagaagagc ggcaggtaat actcgatgcc ggccgacggc acgccgttgc cgatgtcctt
      421 gtagatcggc gcgcggctcg ggtcgccctc gaacgtctcg cgccagcggc ttcggaacgc
      481 ggtgcgcgcg gcctcgtcga acgggaattc gcggccgggc agcaggcgca cgtcgcgcac
      541 cgggtagagg ctgcgctgcg tgtccggatc gaacgcgcgg atcgagtcga cctgatcgtc
      601 gaacagatcg atccggtacg gcagcggcga gcccatcggg aacaggtcga tcagcgagcc
      661 gcgcacgcag tattcgccgg gccgcacgac ctggctcacg tgctcgtagc cggcgagcgt
      721 cagctgcgcc ttcagcttcg cttcgtcgag ccgctcgccc tgcgtgaacg agaacgtgta
      781 cgcggcgagg aacgacgcgg gcggcatccg gtagagcgcc gtcgtcgcgg gcacgagcag
      841 gatgtcgcag cggccttcgc cgaggtcgtg cagcgtcgcg agccgctcgg acacgagatc
      901 ctggtgcggc gagaacgtgt cgtacggcag cgtctcccag tcgggcagca cgcgcacgcg
      961 cgcgtcgggc gcgaagtagg cgagctcctg cgcgagccgt tgcgcgtcga ccgcgttcgc
     1021 gcagatcacg gcgagaagcg gcacctgcgc gcggtgcgcg gcgagatagc gggcgatgac
     1081 gagcgcgtcg gcggagccgt gcgcgccgtc gaaggcgaag cgctggcccg ccttgacgag
     1141 cgcgacgggg gactgcgaag gggaggcgtt gtctaacata acgagcggct ggttggcgaa
     1201 cgccggatgg cggacgagct cggcgcggcg catcgcggcg aaagacgtat tataaaatcc
     1261 gtccttcgat ttcatcttcc cggcgttccc tttccgtgac ctcccgactt tttgccctga
     1321 ttccgtgcgc cggcaccggc agccgttccg gctcggcatt gccgaagcaa taccgcacgc
     1381 tcgccggacg cgcgctgctg tactacacgc ttgccgcgtt cgacgcatgc agcgagttcg
     1441 cgcagacgct cgtcgtgatc tctcccgacg acgcccactt cgacgcgcgc cgcttcgccg
     1501 gcctgcgctt cgcggtgcgg cgctgcggcg gcgcgtcgcg gcaggcgtcg gtgatgaacg
     1561 ggctgatcca gctcgccgaa ttcggcgcga cggacgccga ctgggtgctc gtgcacgacg
     1621 ccgcgcgccc cggcatcacg ccggcgctga tccgcacgct gatcggcgcg ctgaaggacg
     1681 accccgtcgg cggcatcgtc gcgctgccgg tcgccgacac gctcaagcgc gtgccggcgg
     1741 gcggcgacgc gatcgagcgc accgaatcgc gcaacggcct ctggcaggcg cagacgccgc
     1801 agatgttccg catcggcatg ctgcgcgacg cgatccggcg cgcgcagctc gatggccacg
     1861 acctgaccga cgaggcgagc gcgatcgaat gggcgggcca cacgccgcgc gtcgtgcagg
     1921 gcagcctgcg caacttcaag gtcacctatc cggaggattt cgacctcgcg gaggcgatcc
     1981 tcgcgcaacc ggcgcgcgct tcctgaaccg catcttcacc atcgcatcac actcggatcg
     2041 aatcacatgg atttcagaat cggacaaggc tacgacgtgc accagctcgt tcccggacgc
     2101 ccgctcatca tcggcggcgt gacgatccct tacgagcggg ggctgctcgg ccactcggac
     2161 gccgacgtgc tgctgcacgc gatcaccgac gcgctcttcg gcgcggcggc gctcggcgac
     2221 atcggccgcc acttttccga caccgatccg cgcttcaagg gcgccgacag ccgcgcgctg
     2281 ttgcgcgaat gcgcatcgcg cgtcgcgcag gcgggttttg cgatccgcaa cgtcgacagc
     2341 acgatcatcg cgcaggcgcc gaagctcgcg ccgcatatcg acgcgatgcg cgcgaacatc
     2401 gcggccgatc tcgacttgcc gctcgatcgc gtgaacgtga aggcgaagac gaacgagaag
     2461 ctcggctatc tcgggcgcgg tgaggggatc gaggcgcagg cggctgcgct cgtcgtgcgc
     2521 gaagcggccg cgtgagcggg gggcatgaat gggggcgggg cgcggaacgc atcgcgcgcc
     2581 cggcgcgcgc ggcgcgcttc gcgctccacg cggcgccgtg gcctcgcggc ggccttaacg
     2641 gcaatcgatc ggcgcgcggc ggccgatacg gcgtgacggc gtgacggatc gcaccggaca
     2701 tagcggacga aagcgggcgg aagcaggcga tgcggccggc gtgcaagccc gcgtcgcgcc
     2761 ggcgccgcga ggccgtctcg ccgcccgcgc atgaacgaac acgccacgcg caaccgccgc
     2821 gtggcgtgtt cattgcaacg cgagccagcc cggccagccg gccgcgccgc gaacgtgagc
     2881 gaccgcggcg ggcatggccg cgcttacttg ccttccgccg agatcacttg cgcggcggca
     2941 ttgatcactg ccgcgatccg gccgacgtcg cgcagttgcg tgactgtcat cccttgttcg
     3001 ttcttgagca acgcgtagtg cgatttcacg cagaagtggc acttgccgac gatcgacgcg
     3061 gcgagcgcgt acatctcgaa cttgcgcttg tcgacgccgc cgtgcgtggc gtacgcgccc
     3121 atccgcagct cggcgcgctg cgtcttcagg tcggcgtcgt cggccatctc gacatacgga
     3181 taccaggcgt tgttcatccc catcagcgcg gcagccgtca gcgccgcctg ggtttcctcg
     3241 ggcgacagca cgcccgcttc gcggatcgcc ttcacgagca ccgggctctt ggccgcgaag
     3301 gctgcggcga gcgccgcgcc gaccgcgtcc gtgccttcga gcgacgagcg cgagatcgtg
     3361 ccgtcgaggt tcaggcgaat gtccttcgcg tagtcgggaa tctgagcctt aatcgattcg
     3421 atgaattcca ttgatatctc ctatgattgg gccgttaaaa aagcccgcag gcaagacgca
     3481 gcgccgcggg ctttcgtgca tcggacgctt acagcgtcgc gccgccgatc gcgcggttgc
     3541 acgggcagag ttcgtccgtt tgcaggccgt cgagaatgcg caggatttct tccgggctgc
     3601 ggccgacgtt caggttgttc accgacacgt gctggatcgt gttgtccgga tcgacgatga
     3661 aggtcgcgcg cagtgcgacg cccgcttcct tgtcgcgcac gccgagctgg tcgatcagct
     3721 cgcccttgac gtcgccgaac gagtagtggt tcagcttgtc gagatccttg tgctcacggc
     3781 gccatgcgag cttgacgaat tcgttgtccg agctgccgcc gagcaggacg gcgtcacgct
     3841 cttcgaactg cttcgcgagc ttcgcgaatt cgacgatttc cgtcgggcag acgaacgtga
     3901 agtccttcgg gtagaagtag atgatcttcc acttgcccgg gaacgacgct tcggtgacgg
     3961 tctcgaatgc cgactggccg ttttcttcgt gattgttgaa gcccggcttc gcggccacaa
     4021 cggtgaaagc ttcgagttta tcgcccacgg tcttcatgcg gatgctcctg tgtgagttgg
     4081 gaaaaactgc tactgacggt caagctaccg atgcgctgca acgtttccgt gacagcatgg
     4141 ggaagactat aacgctatta tgattttcta tcaatagatt ttaactaacg aacttcatag
     4201 gaattttcaa agacgtcgat agggttcgac catcgggggc aggttcgtcg tgcgtcacgc
     4261 agccgcacgc gctttggcgc tcggaaactc cagcgtgact tcgaggcccg cgtcgggcgt
     4321 gcggttgcgc agccgcagcg cgccgcggta gcgattgacg aggcgcagca cgatcgccat
     4381 gccgaggccg gtgccgtcgg ccttgctgcg cgcggtgtcg acgcgataga acgggcgcat
     4441 cacgagcggc aactgatcct cggggatgcc ggggccctcg tcggcgacga cgagctcgac
     4501 gcgcgcgtgc gtgacccgcg tttcaagcag gatgcgcgcg atgccgtcct gcttgctctg
     4561 cccgtacttg cgcgcgttct cgacgagatt gccgatcacg cggcgcatgt ccgtttcgtc
     4621 ggcttcgatc acggccgcgg gcgcgaggcg gatatcgagc tgcacaccgt cctcgctgac
     4681 gatccgcgcg gcaacctcgc gggcgacctg cgacagatcg acgggctccg gcgtgcgctg
     4741 cgcggggcgc gcgtaatcga tgaacgcggc gatgatgcgg tccatctgct cgatgtcgtc
     4801 gaccatcgcg tccttcgtcg cctggtcgga cgggctcatt tcggtttcga ggcgcagccg
     4861 cgcgagcggc gtgcgcagat cgtgcgagat ccccgcgagc atcagcgcgc gatcggcctc
     4921 gagctgctcg aggtcgcgaa ccatctggtt gaagctgcga ttcgtctcgg cggcgacgcc
     4981 cattccccgc tcgggcagcg gttccggcgt ttggccggag cccaccttgc gggcggcgag
     5041 cgcgagccgc gagaacggct ggttcacgag gctcgtgatg aacgccgagc cgatcagcga
     5101 cagcgcgagc gcgaagaggc cccagcccgc ccattgcagg ccggtgacgg tatcgagctg
     5161 atcgcggtcg agcgcgaccc aatagtcgtc gtcgtcgatc ttgaagctga tccacacgcc
     5221 ggggatgtcg ttgaccgatt gcgcgatcac cgtgtcgtcg cccaggcggc tgcggatgtc
     5281 gtgctcgatc agccggttca ccgattcgtc gggctgcagc ttgaatttgt cggttttctc
     5341 gcgcggatag acgcgcacgc cttcgttgct ctcgagatcc tgcagcagcg cgcggcgcag
     5401 atcgggatcg gaatagagca gggccgtgcg cgtgagcttc acgatggcga cgagctgcag
     5461 cgcgacgcgc tgcgcgcgcg gctcgcgctc gatcacccgg aagctctgga accacgcggc
     5521 gaggctgact gcgatcaaca gcgcgatcag caggaaggtg cgccagaaca gcccgccgaa
     5581 cacgagcgtc aagaggcgcc ggtcgatacg cataggactg gctgtctaac tggcgtcaaa
     5641 ggcgtggcgt cgaggacgtg ttttgcgtcg aaacgaatat caggccgcgc cgtcggggat
     5701 gaacacgtag ccgaggcccc acaccgtctg gatgaagcgc gggctgcccg gatcgggttc
     5761 gatcagcttg cgcaggcgcg agatctgcac atcgaggctg cggtcgaaca cttcgtattc
     5821 ccggccgcgc gcgagctcca tcagcttctc gcgcgacagc ggctggcgcg gatggcgcgc
     5881 gaacactttc agcaccgaga actcgcccgt cgtgagcgga atctcctggc cggatttcgt
     5941 gagcgtgcgc gtcgcgaggt tcagcgagaa ctcgccgaac tcgaacacct cggtggtctc
     6001 ggagggcgcg cccggcagtt cggcgggcgc ctggcggcgc aacaccgcgt gaatgcgcgc
     6061 gacgagctcg cgcgggttga acggcttcgg caggtagtcg tcggcaccca tttcgagacc
     6121 gacgatgcgg tcgacgtctt cgcccttcgc ggtgagcatg atgatcggcg tgcgatcgtt
     6181 gctgccgcgc aggcgccggc agatcgacag gccgtcctcg cccggcagca tcaggtcgag
     6241 cacgagcagg tcgaaacgct cgcgcaccca gagcttgttc attgccgtcg cgttctccgc
     6301 gacatacacg ttgaagccct gctcgccgag atagcggcgc agcagatcgc gcaggcgcgg
     6361 gtcgtcgtcg acgacgagaa tcttggaggg gtttttcgtt tccatgagcg gcatcttatc
     6421 gcgattagga aaaaccgcac ggctgcggct ttcgacgggt tacagtcagt tacaaaattt
     6481 acccgcgcta ttgtgcggag taaagacagt cacgacagac tcctttactc gaagacgaca
     6541 ttcggtggat actccatcca cttaacattt acatggtttg cacgcccgat tctcgcaggg
     6601 tttgttcgtg tgccaaaggt agccggttgc cgcgtgacga agggaacaaa acgacgaaag
     6661 aggcgaggcc cgtgatgcgg ccgacgaaga tggcgttcgt gctggcgttc gcatgcgccg
     6721 gcttccttgc ttcggacttc gcctgcgcgc agcgcccgga acgcggcgcg ccgccgtcgc
     6781 acaaggtgcc gcgcggcaac ggcgcggcgc ggcgtcccgc gccgcccggc gagccgcccg
     6841 cgcgcgcggc cgccgttccg cccgatctcg agcagcgccg ccgcgacggc cacatgacgc
     6901 cggaagaacg gcatctgttg cgccagcata tcgaagacgc ggtgcgcgaa ctttacaaac
     6961 gttgaatcgt taaatccggc gtatctccgg cgtatctccg ctcgcggttc gtcgtccttc
     7021 atccgtcgtt cttcgccgga aaaattccgt agcaattcga tcgtcaactg cgcgccgccg
     7081 cgagccgttg aatcgccatc acggatggcc tcgcgcatcg cgagccggcg tggcttgcct
     7141 ctttcggaga acggtcgacg atgagcgatt cgaggacgcc cgggcggccc ccggcgaagc
     7201 cgcagcggat gccggcggcg atgcagaccc tgctcgacgc ggacgacgcg cgctttctgc
     7261 tgacgcgcac cggcttttcg ccgccgccac gcgcgctcgc gcgcttcgtc ggcatgacgc
     7321 gcgcgcaggc gctcgccgaa ctgctcgacg gcgcccgcac gcaaagcgtg acgtcgccgc
     7381 ccgactgggt gcgcgagccg ccgccgtcgc gcgcgatgcg cgccgcgttc tcgcccgacg
     7441 agcggcgcgc ggaacaacag cttcgcaatc gccgctacga cgagctgcgc gcatggtggg
     7501 tgcgcgagat gatcgtgacg ccttcgccgc tcaccgagcg catgacgctc ttctggcaca
     7561 accacttcac gtccggccag gataaggtac cgtttccgca aacgattgcg gctcagcatg
     7621 cgctgctgcg cgccaacgcg ctcggcaatt tcggcgcgat gctgcacggc gtcgcgaagg
     7681 atccggcgat gctgcagtat ctcgatggcg cgagcaatcg caagggccgc ccgaacgaga
     7741 acttcgcgcg cgaggcgatg gaacttttca cgctcggcga aggccactat acgcagcgcg
     7801 acgtgttcga ggccgcgcgc gcgtacaccg gctgggggct cgatcccgat gcgctcacgt
     7861 acgtgttccg gccgaacgtt cacgacgacg gcgtgaagac cgtgctcggc gaaaccgggc
     7921 gcttcgatgg cgacgcggtg ctcgacatcc tgctcgggcg ccccgagacc gcgcgcttcg
     7981 tcgtcgcgaa gctgtggcgc gaattcgtct ccgatgcgcc ggatgcgggc gaggtcgagc
     8041 gcatcgccgc gcgcttgcgg cagagcgatt acgacatccg cgcggcgctc acggagctgt
     8101 tttcgtccga cgcattctgg gccgagcgca accgcggcgt gctcgtcaag tcgccggcgg
     8161 aattcgtggt cggcacggtg aggctgttcg acgtcgatta cgtcgatgcc gcgccgttcg
     8221 cgaacacgtt gcgcgcgctg ggtcagaacc tgttctatcc gccgaacgtg aagggctggc
     8281 cgggcggcgt gagctggatc aacagcgcga cgctgcttgc gcgcaagcag ttcgtcgagc
     8341 agatgatgcg cgcgaccgag gcgcccggca tgcgtgcggc gcccgtttcc cgcgacatgg
     8401 cgggccagcc ggcgccgacg cggcgcggcg cgatgcgctt cgatctcgac gcgtggcttg
     8461 ccgcgtaccg gacgaagccg caggcgcagc cggatctgtc gacggagctg caactgcagc
     8521 acgcggtgct gccgatttcg ccggtcgcgg cgatcgaggc gggggcgacg agcggcgcgt
     8581 atttgcaggc cctgttgatg gacccggcgt atcaactgaa gtgaagaaca tgaacacgat
     8641 gacgatgaga ctccgcgcga tgcggcgttg cgcgggccgc gtcgaatgcg aaacgaggaa
     8701 ggcagcatga aacgacgtga ttttctggcc ctggcgagcc ttgccggcgc ggcgggcgta
     8761 tcgttgccgg tgccgtatgc gttcgctgcc gcgccgggcg agacgagcgc aacgggggcg
     8821 atgggagcgg tgggggcggc gcgcgccgca cgctactcga acctgctgat tctcgtcgag
     8881 ctcaagggcg gcaacgacgg gctcaacacg gtgattccgt acgcgaatcc gctgtaccgc
     8941 acgctgcgcc cggcgatcgg cgtcaagcgc gagcaggtcg tgcagctcga cgagcgcgcc
     9001 gcgctgcatc cggcgctcga gccgctcatg ccgatctggc gcgacggacg gctcgcgatc
     9061 gtcgaaggcg tcggctatcc gcagccgaat ctgtcgcact ttcgctcgat cgagatctgg
     9121 gataccgcgt cgcgcgcgaa cgagtatctg cgcgaagggt ggctcacgcg cgcgttcgcg
     9181 caggcgagcg tgccgcccgg cttcgccgcg gacggcatcg tgctcggcag cgcggaaatg
     9241 gggccgctcg cgaacggcgc gcgtgcgatc gccctcgtga atcctgcgca gttcgctcgc
     9301 gcggcgcgac tcgcgcagcc cgtgtcgctg cgtgagcgca accccgcgct cgcgcacgtg
     9361 atcgatatcg aaaacgacat cgtcaaggcc gccgatcggc tgcgtccgca tgcgggcacg
     9421 cccgcgctcg cgaccgcgtt tccgggcggg ccgttcggcg catcggtgaa gaccgcgatg
     9481 caggtgctcg ccgcgtgcga cacgccgcag cgtacgccgg cgccggggca gggcgtcgcg
     9541 gtgctgcgcc tcacgctgaa cggcttcgac acgcatcaga accagcccgg ccagcaggcg
     9601 ggcttgctcg gccaactggc gcaagggctg gtggcgatgc gctcggcgtt gatcgagctc
     9661 gggcgctgga acaatacgct cgtgatgacg tatgcggagt tcggccggcg cgcgcgagag
     9721 aatcagagca acggaaccga tcacggcacg gccgcgccgc atttcgtgat gggcgggcgc
     9781 gtgcggggcg ggctgtacgg cgcgccgccc gcgctcgacg cgctcgacgg caacggcaac
     9841 ctgcctgtcg ccgtcgattt ccgtcagctt tatgcgaccg tgctcggccc atggtggggg
     9901 ctcgacgcgg cgagtgtgct caggcagcgt ttcgagccgc tgccgttgct gcgcgcctga
     9961 tacgcgggag cggggcgtgc gcggcggagg gcggcgcgcg tcagcggcgc cgcgcggcgc
    10021 gccatgcgat ccacagcttg cggatcggcg tgagcgcgat ccgctgatgc agcacctgaa
    10081 agccgtcgcg ctcgatctcg tcgagcaccg cgagcgcgag cgcgccgagc gcgcgcagcg
    10141 tgcgctgcgc gcgccgctcg tcggcgggaa tgccggatag cgacgcgttg agtgcgtcgc
    10201 gcgcgcgtga cgtctggaag cgcatcagct cggtgtaggc ggggctgtag cggcggttga
    10261 ggagatcggc ggccgtcacg ccatagcgtt gcaactcgtc gatcggcacg tagatgcggc
    10321 cctgccgcgc atcctgcccg agatcctgca cgaattgcgc gagcgtgagc gcctggccga
    10381 gcggctgcgc ccagcgcgcg ccgttcgcgg tgggccggcc ggcgctggcg ctggcgcttg
    10441 cgacgagcgc ggcgaacatg ccgcccgttt gatcggcgta acggcgcagg ttcgcgaagt
    10501 ccagatagcg cgcctgctcg aggtccattc cgtaaccggc gacgagcgtg cgcagcgcat
    10561 cggtttcgcg cgcgatgtcc ggatgatgcg cggcgagcgc ttgcgacacc ggatgcgacg
    10621 gatggccgga tgcgagcgcg gcgagctctt tttgccacca cgcgagcttg gtgtggccga
    10681 cggtcggatc gctgacttcc ttcaccgttt gctcgagctc gcgacgcagc gcgaacagcg
    10741 cggcgacgag cggctggcgc gcgagcggcg cctggcgcag cgcatagtaa aaactggagc
    10801 cgggcggcgc ggctttctgc tggcagtatt cgtcgaaatt cacggggacg gaacgagtga
    10861 ggcgggatcg gctcggcgcg gggagcgcgg gcgctggacg gcccggcatc gcgccatgtt
    10921 gcggcgacaa cggcgaattc tagcatcgcg gcgcaagaga ggccggccgg tagagacaag
    10981 cgtggggaga tcggttagaa tctcgcgctc gcgcttttcg ggcagtcgcg aaagcggctt
    11041 gcgaccccgg gtggcgcaac attttttcgc gtgcgtgagt ggcgaaattg gtagacgcac
    11101 caggtttagg tcctgacgcc cgcaagggcg tgccggttcg agtccggcct cacgcaccat
    11161 cagcatcttc atacggcacg ataaagcacc acaaggcatg cgttttcaat ggcttgcgtt
    11221 gctttttgag cctgcccctt ccctcccaat cgtcacgctg aactacgtct cgccgcgcat
    11281 aagttacgca gggcgccgtc agaaagacac cggctggtgg ttgcgcgcgc agaggtctat
    11341 gtcgagggcg cgccaagggc gtgcggaatt cgactgttcg tgatacgaag gctgcggcgc
    11401 gggtttgccc gcgcccgaat ctattgcgta tgggtgggag ctatcggcgg ctcacatttc
    11461 tcacattcgc ctcgcgaatg cgtacattga gcggttcgat tgggcgacgt ccattgatcg
    11521 ttgcgatcgg ccgtacgcgt tgttctacct cgatccgccg tacttcgaga ccgaagggta
    11581 cggcgttgcg tttccgttcg cggaatacga gaagatcgcc gagcggctgc ggtcgatcaa
    11641 gggggcgggc gatcgtcagc ctcaatgacc atcctgaaat ccggcgcgta ttcgcgggct
    11701 ttcatatcga gagcgtgccg attcagtata cggtcggcgg cgcaaagggc gtcgagcgcc
    11761 gcgagcggat tactttgggg cgactcggcg gagccagtcg gattgtttgg acgcgtgctg
    11821 ccggcgcggt aatcgcgccg gcgggttcag cttcagatat cgacgtaggc ggggagcaag
    11881 tcttgatcga cgagccggat ctcgatgcga ttcgcgatcg cgacgtgctc gggattgtcg
    11941 accgagaacg gggcgtccgt gacgctgacg atgatcgtgc cggtctgttt gcctttggcg
    12001 gatacgggaa tcagcgctcg tgcctcggga acctgctgtt gcgtgatgac cttcggcaag
    12061 tagagcatcc agccgacacc gggcttgtcg tcgaatactt gtttgtcgaa gtagccctcg
    12121 ggcgatgctt ctacgacaag cggattgaac gcggcaacaa tggtagtgac gacgtctgcg
    12181 agatcttgcg atttcgcata gcagtcgggg acgcccagac gtgtcgaaaa tcggtccggt
    12241 aagacctttt cgtctgatac atgacacgac atcgatgcgc cttcgttggg gcgtgtattg
    12301 ccattccata tcgccgcatg ggaagcgcta tgcttcttgc cgcgctgctc ttcgtttaag
    12361 actgccaatg caggagtaga gggcgagccg tctgcatcaa atgccgggta gagtgtcgct
    12421 tcttcgagcg aattcccttt gagtcgccaa ttcgcgtgcg ccatcagcgg gctcttcgcc
    12481 gcgagcgcag cgacaacttt cgactctcga ctcagcatct cggagaaatt gcgggacgac
    12541 agcgatacgt cccggaacat cgctttgatt tccatgttcg attacggttg gtagacggat
    12601 cggacgccga ggctggagag caagggtgtc atctttcgct ttgtgagctg ggtttgaaaa
    12661 taccacgtca gtcgtgcagg cgggtttgct cgcactcttg tggcctggtt cgtgatctgc
    12721 gtttccatcg aatcgaagcc tttgaagaag tcttcggccc ccggaattga accgtcaagg
    12781 aactgatcgt agttgccttt ggtttcctgg agcatgcatt cacccggctg gaaaccatcg
    12841 aaatcaacct cgagccatcg ccattcctcg ctccaacggc aggcttcggt atcgaacgga
    12901 aagccggtga tccgtgcttg gtagcggtaa gagttccagt ttacaccgtg atttcgacga
    12961 atccgcgtgc cagcgtcggg cgggcatttc ttgcagcttt cgccggtgcg cggcagtgct
    13021 cgcacatcgg gcgtcgcctt gctgtcctcc ttcggcgtat cacccgacag actcgccgtt
    13081 cccgccaccg tcgcgccgcc cagcaaggcg acgccaacgc gcgccaagat cggcccaagc
    13141 tccaccgccg ccgcttccac gattggcacc accaatcccg ccatgttcca gccctccgtc
    13201 cggatgttcg atgcgccatt tgatgacgcg cagataatca tgaaagcgcg cgtcggccga
    13261 gcggccgggg cgcgtgagcc aagccttcgt cgcgggcttc tcgtagaagc ccggcgcgta
    13321 cgcttcgagc ctcaggaacg cgacgatgtt ctcgtcccgc tcgatgccga acgtgcgcgc
    13381 ggcgcgatac gcggtccaca accgggacga cagaccgccg tcgtcggcaa acgccggatt
    13441 ctccttcacg agatcctgcc ggacgcgctc gacgaagccg cgctcgtcga tctgcgccag
    13501 tccggccacc tgttctgcgc tcagttcaag catgcggatg cactccggtc agccgcccgt
    13561 cgatctcgac gagccagtcg tacgtcgcga cgaagaattg cgagcgctgc gcatcgctca
    13621 tcacgcgcgc gatgtcgggc atgatgcgcg cgtcgtagaa ccggaacagc gcggtgcggc
    13681 cgtccggcaa ccgtacgtcg aggtgctcgc gcagctcggc ggctagccgc tcgaacggat
    13741 acgcgctgat cagccacgac atgccgaccg gcccggccgc gagctcggcg agcacgcgcc
    13801 ggatcggccc cggcgcgatc gcgtagtcga tcagccacgg gccgtgatcg gcgagcgatg
    13861 cgtcgggcgt gcggtcgaac agcgcgatcg aatagttcgc gcgccgcagc gccggggcgt
    13921 ccgacgcttc ggcgaagagc agcgcgtcga ccaccgcgaa gagccgcgcg ggcagcgtga
    13981 tctgctggcg gcgcatctcg aaatgcgctt cgatattcgg cggcgtcatc atccgcgtgc
    14041 gaccatcgtc gcggcgttct tggccgccgc cttcaggcat tcgaggcaga gcgtggggaa
    14101 aggggcgacc gcggccgccg ctacggctgc cgatccgccg ggcgagccgc cgtctccgcg
    14161 ctcgcccgcg ccgacgtcgt cgatcgttcc ggtgccctgc gatgcgatca actccgcgcc
    14221 gcaggccgtg cgcatgccct cgacggcggt gtcgcgctcg ccgatcgtgt gcgggtagcg
    14281 gcggccgagc aagtcgggaa ggatcgggaa aatgcccttg cagcgcgggc aaagtacctg
    14341 gtggccgacg ccggccacat tgcgtccgtt gagcgtgaac gtcggcgcgc cttcgagcac
    14401 cttgccgccg tgtgtcgtcg tgtcgccgac gcagatgatc gcgcgcttgg ccactggccc
    14461 ctctcatgga aattggcgtg caaatttacc atcgagcgcg cccggcgggc gactgttacg
    14521 gttgtgcagt cacgacacct gtcagttctg tcagttgtgc ggcatctcgc gtcggcgtgt
    14581 cttcctcatc gtcggacgtc aatgacgcgt ggtgcttggc ggctgtgagc ggatcgccgt
    14641 attcgtcgtc agtcggatgt gcaacccaaa gaggcgtaac ccaatggccc cgaactcgat
    14701 agacgccgat cgaccatccg ctcccgggcg tatctcacgc gccgttaacg ctccacgaaa
    14761 aagtcggatg gccgtagtcg ccactaatag ttgggccgct tacgttgaag aactgtgctg
    14821 tggtgccgac tacggacgag gatcccccat tgtccgctcc gacgggattg tcccagttga
    14881 gctgtacgta ggtcgcgtcc ggacatctct tgaccgctgt atcaaggatg tcgaaacggg
    14941 ctgagccgtt tagatctcct ttcccatcaa gcgtactcgt aaaaataagc gtatcgttcg
    15001 gccgtaaata ggccggcgga taatcgccgg accaattgcc cgtgttggcg tatatcgtat
    15061 gcaggacgag agtaaatgat gtgttgttcg tgagctcgat ggtattcgct ttgcccattt
    15121 ttaactccac tggatttatt ggttaatcgc catcgatgtg atgggaaaag tgtgcgagtt
    15181 tattagagtc tagattttga aaggacgaaa ctatcaaatc tggtagtgta tgcgtccctt
    15241 tttaatgagc ttattaagct gcgaaaatgg gagattgtca ggctcgtcgt tgatcgacgg
    15301 tgtgcggtgg gggctgccat cttccgaaaa gttgccttgg tgttgcggca aaaggacacg
    15361 cagtcggaac ggcgacgaca gtgccggtca gcctctgggt ctgctcgatg ttgagggggc
    15421 ttcggtcgct cgagggacgg gcgatcgtca gcctgcatga ccatcccgag attcgacact
    15481 tgtttatcgg cttcgacatc gaaagcgtgt cgattcggta cacggcaggc ggaggaaagg
    15541 gcggtgagcg tcgcgaactg atcattttta attgggacga tgcagcggag ccagccgggt
    15601 tgttttgacg aaagctgccg gcacggtaat cgcgccggca ggttcagata tcgacgtagg
    15661 cgggaagcaa gtcttgatcg acgagccgga tctcgatgcg gttcgcgatc gcgacgtgct
    15721 cgggattgtc gagcgagaac ggcgcgtccg tgatgctgac gacgatcgtg ccggtcagac
    15781 gcttccctgc ctccggaacg gttatcaggg cgtgcgcttc cggaacctgt tgctgcgtga
    15841 gagcgaatcg cgccgtagaa gtcacagcgt tcagcatcac cttctagcac attgcaagcg
    15901 gaaccgaaat tgcagcacgt tcaaatggcg cctaccgctt tatgcttttt tatcaaggag
    15961 caatcggatg aaaaatgtct tgtcccacat tgacgtgctt ccaggagtac tgggcgaaag
    16021 cattcgagta atagtagagc gccgtgatcg tcggcacgtt gttcgtgatt tggcaaagcc
    16081 ccgaccacgt cgtaatactg ttgtagcggg ccgcggtatt gttccaattc acggaaaacg
    16141 tgaccaatgt cacttgatct aggccgttat ttgccggcgg tgctgcatag aaccagccag
    16201 aaagagaaaa ggtttgtccg gtggttccgg acggtgaaac ataggtgccg gtaatggctc
    16261 cagtcccgct gatggaggcg atcgtcatgg tcgagcctag ctcgttgagc caggagccga
    16321 tcgggttctg acaattcggg gcggttgaag tgtcagccca cgcaggttgt gcaaaggccc
    16381 ccagcatggc gagcgatacg agcgtctttt tcattttcag ctccttcctt tgtgacggcg
    16441 cggatctctt gtattggcaa aaccgcgctg cggctggcct cacacccaat ccggcgcgta
    16501 tatcgagcga gttcgactgg tgacacaaga aatcatccgc ctatgagaag tggtcgaggg
    16561 tgacgtattt ccgtgatttg ttgaaatcgc gtgcaagacg aggttgaaaa ttaactgaat
    16621 gtgttctgtc gcttgatttc agggggtgcg ctttatgtga aatgaaatgg aaaattcagc
    16681 ataggttgaa aagtaatggt ttacaagtgc aacttgattg cggttggtct ttaaatttat
    16741 cgaatgattt gcgtggaacc ggtgtgatgg cgaattttag tgagatcggg taagcggagg
    16801 taaaataatt gagtgaatgt ttgaatcgta ttcggttttt attgatcgag ccttgatggg
    16861 tgttttcgct tgatttcgaa gccgatcccg gtggggaggg gcgctctaat agaaaaccaa
    16921 gccctgaaag tgaaaacctc gtgggcctct ttatctaggg cgcggaaatg cgagcggagc
    16981 tggcgaacgc ctgtccgtgt gatattcgct cggcgtggga cgaggatcga ctcatcgggc
    17041 gcgcgatcgc gcgtggtttc gtattcgacg atgcgataga ccgcattggg tgggcgatgg
    17101 gccgggtggg agatcacgcg gtcatgtcag tcgagatcga ggctgccgct ctccggaaaa
    17161 gggcgggttt cctctggcgt gggtgcatgc ggggcgcgaa cccttgttct ttctctacag
    17221 gcgaatcatc caatggtggc atatttgcac gaacccgaca gcaaatcgcc gagcatctcg
    17281 accttgatca agcggtcgct tcccggttcg tcgataagct gagggctcga ctgccgcttg
    17341 gcaacgaccg atgaaattcg aattgcccat atccggcacc tacgcgagat cgcggcgagc
    17401 cgagcgcacg atgaccaagc acgtcgatcg cgaagctcag atgccgctgc tggcggaaaa
    17461 gaaagcgctg cccgcttcgc tccgccgctt gtcatcatgc atgccgacgt accgggcgcg
    17521 cctgccggag tgagggagcg gcgtcccgtc attgccgccg gaccggcgag cgtgaagggc
    17581 tgctcgagcg cgtccgcagc gaaggctgcg cccgtcggcg agttgacgcg ccaagcggtg
    17641 cgcgccagcg gatcgccggt caataagccg accgataggc ggttccttga tcgaaccggt
    17701 tctgccagtg cttcaggtat tgcgcggcga gcgcagggtt gttccagacg acgagcacgt
    17761 tttccgaatt gcgcgcggcc gcggcggcgc tgtagttgaa cgaccccgtc tccacgtggc
    17821 ggccgtcgac gacgatgtac ttgtcatggt ggatcgcgta gcgatcgatc gtgcgcgtcg
    17881 gtactttcgc gttgacgagc agattgagcg cctgcttcga cgccttcgag cgattgccgt
    17941 cgttgtcgac gacgatcgcg acgtcgacac cgcgccgatg tgcgtcgagc agcgcgcgca
    18001 cgaccttcgg cgacgtgaac gaatagccgg cgaggcgcag cgacgcgcgc gacgtgccga
    18061 tcactttcaa cacgagtgct tcggcgccgc cgtccggcga gaacgcggcc tcgacgacct
    18121 ggcccgccgg cgcttgcttc gcggatgacg gcagtgcgtc ggcgatcagc gcgacgaggc
    18181 gctcgagcag tgattcggag gtcgtcttgc tgacggcggg cggggcgccg cacaggaaag
    18241 cggtggcgag acatgcggcg gcgaaccgct tcggcaactg catgagaggg gcggacgttc
    18301 gaaactgagg aggacgagag tgtaacggca tcggcgtggt tttcgtcgat tctccggaaa
    18361 gttcctgtcg acgcgcatcg ccgccgtcac gctcgttcgc gcgtctcacc ccgccgacga
    18421 acggcgccgc gcccaccgtg ccgaacgtgc atcgtgccgt tgtgcttttt cgaccggtca
    18481 gtaaccgaag ctcgtcgcca tttcgtcgat cagttgccgc tggaatgcgt tgaaacgctc
    18541 gccgggctgc tgcgcgatcg cgagctcgag catcggatcg gcgacgtcgg tgcgcatgcc
    18601 cgccagtgcc tcgacgatcg catgcccaca aaacggtacg taggcctccg aataaccgcc
    18661 ctcgtgcacg atgacgagcc gtcccccgca gtgccgctgc gcggcctgct tcagcgcatg
    18721 cgtcatgtac cggtagctgt cgctgtgcag ttgcatccgc gcgagcgggt cgaccgcatt
    18781 cgcgtcgagc ccgctcgcga cgatgacgag ctccggccgg aacgcatcga gcgcgggcag
    18841 cacgattcgc tcgaatgcgt atcgatacgc gtcgtcgccg gcgcccgcga ggagcgggac
    18901 gttgacgttc gcgcccgcac ccgcgcccgc gccgcgttcg tcggcgccgc tgtagccggg
    18961 cggaaagcag cggtcctgat gcagcgagat cgtcagcgtg ttcggatcgt cgtagtagat
    19021 cgactgcgtg ccgttgccgt gatgcacgtc ccagtcgatc accgcgacgc gctcgacgcg
    19081 atgtttcgcg cgcgcggcct cgatcgcgat cggaatgttc gcgagcaggc aaaaacccat
    19141 cggcttgtca cgcaggcagt gatggccggg cgggcgcgac agcgagaacg cgttggccgt
    19201 gcgctcggcg agcaccgcgt cgacggcggc gagcgcgagc cccgcggata gcgccgcgat
    19261 ctcgtagctg ccacggccga acggcgcgag ttcgccgaga tcgccgccgc ccgcgtcgct
    19321 cgcgcgcttg aacgcgtcga ggtagtgcgc ggggtggatg cgccgcagat cgtcgtcggt
    19381 cgcggcgggc gcgctcgaca tgtcgagttt cgccgcgagc ccggacgcgt gcacgagcga
    19441 cagcagacgc cgcttcgaat cgggcgattc cgcatagccc gcgctcgacg gcggctgcac
    19501 ccagccgccg accggaaaga acagcgcatg cgcgccgccc gtgtgccaga aagtgcgttc
    19561 gtcggtgaag aaagcggttt ttgtcatggc gatgagccga agcgaagagg gaagggaaag
    19621 caacgacacg gagtgtcgag gcgtcagcgc gcgtcgtgct cgacgcgcag catggccgcg
    19681 agcgagacga gcgagaccgc ggtcgcgatc gagaacagcg cgcgcagcgt gccgccgccg
    19741 tcgagcatca gtccggcggc gagcggcccg gcggcgagcc ccgaaccgat cacgagattg
    19801 agcgtcgcga tcaggcgccc cgtcgcgtcg agggccgcga cgctcgcgag catgaacggc
    19861 aggacgaacg tccatgcgaa cttgaaaccg aagatcgcga gcgtgtagcc gttcgcgttt
    19921 ggcgcggcgg caagcgcgac gagcgacgcc gcgaggatgc cgtatccggc gagcagcatc
    19981 gcgcgccgcg ccgcacggcc gcccagatat gacgcgagcg ccgcgcccgc gatgcccatc
    20041 aggctcgcga tcgcgagcac gttgccgctc gtctgcgcgt cgaggccgac ggcggccgcc
    20101 gctttgctcg cgaaggtcca cacgccgccg atcgcgacgt agaacgtcag cacgccgccg
    20161 atcgcaagcg ccgccgccat gcgcgccgct tgcgcccgcg cgcgcggcgc gtgctgcgcc
    20221 cgcccgcgcg gcacggccgg aaagcggcgc gcgagcggcg cggcgcacag cgcgagcgcg
    20281 gcgagcacgg cgtacagcgc gcgcagtccg accatatcga acagatgcgg cagcaggaac
    20341 agaccggccg cgcccgcgat caactggccg acgacccaga gcccgtagac gcgatcgctg
    20401 ttgccgctcg ctgcggcgct cgtcatgcag agcaccatca acgtgccgcc gccgagcgcc
    20461 gttgccgcgc gcagcgcgag tagcggcgcg aagcccggca tccatacggc ggttgcgaga
    20521 ttgcccgcgc agaacacggc ggtcgcgccc cacgcgatgc gccgcgcgtc gatgcggccg
    20581 agccacaggt acgacggcag cgtcgcggcg ctgaacgcgc ccagctccac gaagaagtac
    20641 gtgccgatcc gcgacgccga cagcccgagc tgcgcgccca attggccggc cacggccggc
    20701 gcgacgagca gcagcagcgg cgtgatcgcc gcgaacgcga cgagcgcggc cagcgtgccg
    20761 ctcgtgaaag cgggcgtatc ggcgggcgat gccgcgcccg ccagcgcggg ttcttgccgc
    20821 aatgtcttga tggtcatggt cgt
//
