LOCUS       NZ_JHEG04000001        33990 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8071215
            Orig. end                         :: 8105205
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..33990
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="26"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..33990
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33990
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:18990](-)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(15001..18990)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     misc_feature    complement(765..781)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.4"
                     /tool="antismash"
     gene            836..1570
                     /gene="rimM"
                     /locus_tag="HC643_RS33045"
                     /old_locus_tag="DA73_0400032990"
     CDS             836..1570
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rimM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017741793.1"
                     /locus_tag="HC643_RS33045"
                     /note="Essential for efficient processing of 16S rRNA;
                     Essential for efficient processing of 16S rRNA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="DA73_0400032990"
                     /product="ribosome maturation factor RimM"
                     /protein_id="WP_237265998.1"
                     /transl_table=11
                     /translation="MNYEDAKSAKKDMKQKGRRGQGGKGTGGQGDKRTRGQSTSPSSPS
                     LPIPPSPHPPLSPSPPQFPDGWIEIGTIVAAQGLHGEVRVLSNSDFPERFEVPGKRWLW
                     CPAQMEPQPIELLAGRNVEGKNLYIVKLSGVGDRNRAEELRGYKLLVLESDRPQLGEDE
                     YHVLDLIGLSVYIQESGEFVGTIVDLLSAGHDLIEVRLDSSRDKAQRTVLIPFVTAIVP
                     IVDLEGGRVEITPPSGLLEIYS"
     misc_feature    1958..1971
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.18"
                     /tool="antismash"
     misc_feature    complement(2391..2404)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.99"
                     /tool="antismash"
     gene            2420..4801
                     /locus_tag="HC643_RS33050"
                     /old_locus_tag="DA73_0400032995"
     CDS             2420..4801
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017741794.1"
                     /locus_tag="HC643_RS33050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400032995"
                     /product="phosphoketolase family protein"
                     /protein_id="WP_038080432.1"
                     /transl_table=11
                     /translation="MTLASRPQTKPLSDDELQKMNAYWRAANYLSVGQIYLLDNPLLKE
                     PLKVEHIKPRLLGHWGTTPGLNFIYVHLNRIIKKYDLDMIYIAGPGHGGPGIVANTYLE
                     GTYSKYYPNVSQDAEGIKKLFKQFSFPGGIGSHCTPEVPGSIHEGGELGYSLVHAYGAA
                     FDNPDLIVACVIGDGEAETAALSASWHSNKFLNPVRDGAVIPILHLNGYKIANPTVLSR
                     LSHKELESLFIGYGYKPYFVEGSDPETMHQLMAATLETITHEIKEIQEDVRNNGFSQRP
                     QWPMIVLRSPKGWTGPKEVDGKKTEDYWRSHQVPFGELQGNPDHLRLLEEWLRSYKPEE
                     LFDENGTPIAELLELPPKGHRRMSDNPHANGGLLLRDLKMPDFRDYAIDVTEVGRTIGE
                     ATKVSGKFLRDVMKRNLDSANFRIFGPDETKSNRLDAIFEVTDRTWLAEKYPYDDALSP
                     DGRIMEILSETTCQGWLEGYLLTGRHGFFSCYEAFIHIVDSMFNQHAKWLDTCHHIPWR
                     RPIASLNYLLTSHVWRQDHNGFSHQDPGFLDLVVNKKANVIRIYLPPDANCLLSVTDHC
                     LRSRNYINVIVAGKQPALQYLPMDAAIKHCTKGLSIWDWASNDQGGEPDVVMACAGDIP
                     TLETLAAVDILRQNFPDLKVRVVNVVDLMKLQPASEHPHGLSDADFDSIFTTDKPIIFA
                     FHGYPWLIHRLSYRRQNHANLHVRGYKEEGTTTTPFDMVVLNDLDRFHLAMDAINRVPQ
                     LGYKAAYVKQALQDKLIEHKHYIHKYGEDMPEIREWKWPY"
     gene            5009..6055
                     /gene="gap"
                     /locus_tag="HC643_RS33055"
                     /old_locus_tag="DA73_0400033000"
     CDS             5009..6055
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016870509.1"
                     /locus_tag="HC643_RS33055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033000"
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_038080451.1"
                     /transl_table=11
                     /translation="MSKLKVGINGFGRIGRLVFRAGIDNPNIEFVGINDLVPPDNLAYL
                     LKYDSTHGSYKGQVEAKEDGIVVNGRFIPCVSVRNPAELPWGKLGADYVVESTGLFTTF
                     EGAANHLQAGAKRVIISAPTKDPEKVPTLLVGVNHHLFDPAKDTVVSNASCTTNCLAPV
                     AKVLNDKFGLTEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNIIPSSTGAAKAVAL
                     VLPELKGKLTGMAFRVPTPDVSVVDLTFKTLSATSYKEICAAMKEASEGALKGILGYTE
                     DEVVSTDFQGDSHSSIFDAGAGIELNSNFFKVVAWYDNEWGYSNRVIDLMLAMAQKEGL
                     LERTAVAV"
     misc_feature    complement(6092..6110)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.88"
                     /tool="antismash"
     gene            6418..7851
                     /gene="pyk"
                     /locus_tag="HC643_RS33060"
                     /old_locus_tag="DA73_0400033005"
     CDS             6418..7851
                     /EC_number="2.7.1.40"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pyk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015141377.1"
                     /locus_tag="HC643_RS33060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033005"
                     /product="pyruvate kinase"
                     /protein_id="WP_038080449.1"
                     /transl_table=11
                     /translation="MRRTKIICTVGPATSTPERLQSLVDAGMNVARLNFSHGEHAFHGQ
                     TIKYLRQISSATQKPLALMQDLCGPKIRLGVLPQEGITVEAGQEVTFVLQKEGKSADEI
                     PLPLPTLFAMVRRGEPILINDGRIKVIVCDRDADRIRAQVIIGGLISSNKGVNLPETRL
                     PVTSITEKDLSDLRFGIQLGVDLVAVSFVRSPQDLEPAQRMIEGANANIRIIAKIERRE
                     AVENIDEIIEVADGIMVARGDLGVEMPIEQVPLIQKDIILRCNRAGKPVITATQMLESM
                     ISAPDPTRAEVTDVANSILDGTDAVMLSGETAVGQYPVAAVKMMHSVAVRTENSLKEGA
                     RQALWNYDAGSLSVTESLAEAVCRIAYETGAKAIVCHSSSGNTARLISKYRPTTPILAL
                     TPCDTPYRQLALSWGIEPLLIQSVYTAEEMLINVEKTLLETELIQQGDRVVITSGVPIG
                     KSGTTSLVKVHTIGQPISA"
     misc_feature    complement(8106..8121)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            8346..8609
                     /locus_tag="HC643_RS33065"
                     /old_locus_tag="DA73_0400033010"
     CDS             8346..8609
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017741821.1"
                     /locus_tag="HC643_RS33065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033010"
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_038080430.1"
                     /transl_table=11
                     /translation="MSKSISITDSRNELLQLPEQLGNEPVIVTNQGLPVMVAISYEQYI
                     SMLETMEILSDPEFKEQLIAGIQEDREGQRVSWAEAMKELEW"
     gene            8610..8921
                     /locus_tag="HC643_RS33070"
                     /old_locus_tag="DA73_0400033015"
     CDS             8610..8921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017312534.1"
                     /locus_tag="HC643_RS33070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033015"
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_202048679.1"
                     /transl_table=11
                     /translation="MMEYEIEFIPLAIELLKKVKDQREQKALRQKIEKLKIEPEKQGKA
                     LTGQFQGYRSVRAVGQRYRIVYRVDRNRIIVVIVGVGMRREGERQDIYAILENELDEE"
     misc_feature    complement(9072..9088)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.11"
                     /tool="antismash"
     gene            9654..10838
                     /locus_tag="HC643_RS33075"
                     /old_locus_tag="DA73_0400033020"
     CDS             9654..10838
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF008965.0"
                     /locus_tag="HC643_RS33075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033020"
                     /product="transaldolase"
                     /protein_id="WP_038080428.1"
                     /transl_table=11
                     /translation="MSKNLLEQLREFTVVVADTGDIQAIEKFKPQDATTNPSLITAAAQ
                     MPEYREIVDETLLQAQKDAGRGASQKDVAALAFDRLAVSFGLKILQIIPGRVSTEVDAR
                     LSYDTEATVAKARDLIAQYQAAGISRDRVLIKIAATWEGIRAAEILEKEGIHCNLTLLF
                     GLHQAIACAEAGVTLISPFVGRILDWYKKETGRDSYPSTEDPGVLSVTKIYNYYKKFGY
                     KTEVMGASFRNIGEIIELAGSDLLTISPALLGELKATIGDLPRKLEPSKAATSDIEKIP
                     MDKATFDKMHAEDRMANDKLDEGIKGFTKALETLETLLAERLARLDGKSTLSHATQDIF
                     HVYDLDGDGFITREEWMGTDAVFDALDVNKDGKITPEEMGAGLGAVIQMAEVAK"
     gene            complement(11112..11606)
                     /locus_tag="HC643_RS33080"
                     /old_locus_tag="DA73_0400033025"
     CDS             complement(11112..11606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017741829.1"
                     /locus_tag="HC643_RS33080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033025"
                     /product="hypothetical protein"
                     /protein_id="WP_038080426.1"
                     /transl_table=11
                     /translation="MEEENITVTEAIELLFGSASLQQAIQAEDEADCDVSAGLDWDNQA
                     YLAFIQNPALLGRLTELRVSLNCEIQRLLAERNLGVGENAAVEVARLRLLSRLRLPEQT
                     VIPILKTTLMCDDLYKEEFINDTQVLRNLLSVLLLDSDWEDIATAAGNAVRDQVMLLII
                     A"
     gene            11825..13039
                     /locus_tag="HC643_RS33085"
                     /old_locus_tag="DA73_0400033030"
     CDS             11825..13039
                     /EC_number="2.7.2.1"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008776 - acetate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017741831.1"
                     /locus_tag="HC643_RS33085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033030"
                     /product="acetate kinase"
                     /protein_id="WP_038080425.1"
                     /transl_table=11
                     /translation="MKILVLNAGSSSQKSCLYDIAGDTFPQEPLKPLWEAKVDWTHHQG
                     FAEIEVKTATGATLEEEIPSNSRSEVVARMLDTLYSGSTQVIDRPSDIKVVGHRVVHGG
                     EDYRESVVITEDVKGAIARLATLAPAHNPVNLEGIEAIEQNLGGITQVAVFDTAFHAQI
                     PDAAAIYPGPYEWVEQGIRRYGFHGISHQYCTQRAARILGRDLAGLRLITCHLGNGCSL
                     AAVKDGRSIDTTMGFTPLDGLMMGSRSGAVDPGIIIHLLRQSDYSADKLDNVLNKASGL
                     RGISGVSGDMRQIRQEISQGNSRAQLAFDVYVHRLRSYIGAMLASLGGLDALIFTAGVG
                     ENDAVLREVTCEAFGFLGLKIDKEKNKHKPVDTDISTPDSAVRVLVIHTEEDWEIAREC
                     WRLVK"
     gene            complement(13099..13998)
                     /locus_tag="HC643_RS33090"
                     /old_locus_tag="DA73_0400033035"
     CDS             complement(13099..13998)
                     /EC_number="3.6.1.27"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017323612.1"
                     /locus_tag="HC643_RS33090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033035"
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="WP_038080423.1"
                     /transl_table=11
                     /translation="MLSLLLSTAACPSDIDLGFVELGWFKVIVLGIVQGITELLPISST
                     AHLRIIPALLGWKDPGSAFSAAMQLASIAAVISYFWYDLKKMTGATVRAISEQNYLDRY
                     FRLAVGVLVGTIPICISGLLLKKTLNACNSPFRTLAVVGLASIVMSLLLAIAEKIGNRD
                     RDFNQLSWKDGIWVGISQALALIPGVSRSGSTLTSGLFLGMERETAARFSFLLGLPAVV
                     LAGALELHTLFKAGLNLNGWITLIIGLITASLSAFAAIYGLLRYLEKHSTWVFVWYRFV
                     MGIFLLIGITAGFLSDRV"
     gene            complement(14157..14948)
                     /locus_tag="HC643_RS33095"
                     /old_locus_tag="DA73_0400033040"
                     /pseudo=""
     CDS             complement(14157..14948)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016816.4"
                     /locus_tag="HC643_RS33095"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033040"
                     /product="M55 family metallopeptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKVYISADIEGISGISHWDEATQGQQN"
     gene            complement(15001..18990)
                     /locus_tag="HC643_RS33100"
                     /old_locus_tag="DA73_0400033045"
     CDS             complement(15001..18990)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (37-429). E-value: 2.7e-106.
                     Score: 347.5. Matches aSDomain:
                     nrpspksdomains_HC643_RS33100_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (545-615). E-value: 3.6e-16. Score:
                     51.1. Matches aSDomain: nrpspksdomains_HC643_RS33100_PCP.1"
                     /NRPS_PKS="Domain: TIGR02353 (641-1325). E-value: 9.2e-199.
                     Score: 653.9. Matches aSDomain:
                     nrpspksdomains_HC643_RS33100_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012409659.1"
                     /locus_tag="HC643_RS33100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033045"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_038080421.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-110, bitscore:
                     368.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-09, bitscore:
                     36.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 1.2e-196, bitscore:
                     653.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKITHRYPKTHYYSSTVNSINLQFDEVGIPPQRLHYFFERRCDAQ
                     PDAIALICDKEHLSYAELDTQANKLANYFLRQGLGSGNRIGILLERSINTYVTLLAILK
                     CGAAFVPLDPSFPQDRIGFIAENASLDLLVTSTAFSSISTCTSCKVLVLDTVVAAIAIQ
                     PATRIAIPDTADELCYIIYTSGSTGRPKGVAVNHSNICNFLTVCTPIYGVCARDRVYQG
                     MIIAFDFSIEEIWPTFIVGATLVAGPTNHQRLGSELTDFLIEQAITVMYCVPTLLATID
                     RDVPLLRTLIVGGEACPQYLVQRWSRESRRILNTYGPTETTVTALWTELLPNRAVTIGR
                     PLPTYSVYILDEELHPVPVGEAGEICIGGIGVAQGYVNLPEQTSAKFICDPYEQNRPQA
                     KLYRTGDLGRVTLDGEIEYLGRIDTQVKIRGYRIELTEIETVLLETPEVENAIVSLVSI
                     NATVQELVAYITLRVPVTDSQELKKCLHTALCQRLPNYMVPAFIEILDAIPTLPNGKAD
                     RSKLPAPTQRMQSHHRTESHALPSLSKEESAIAKIWQNLFPYTKISVDDDFFLDLGGHS
                     LLAANLVSQLREQREFAHVSMLNVYQCPTIAKLAAQLKEQPASTKVPANSCFHRLSHRR
                     YLKCVTLQALGLIVILFCFALQWLLPYLTYSWMQENGASNLESALVSVVALAAIIPLML
                     GFSIAMKWMLVGRVKPGKYLLWGNFYLRWWFVKNLLSITPLHFLSGTPLLNIYYRLLGA
                     KIGTNVYLSSVNIDVPDLVSISADSTIGYDAGLLNATVEEGWLKIGSIKIGNSCFVGAS
                     SVVSANTVIEDNASLEDLSMLPPQHRIPAGEVFAGSPAAKVGVNSSKAMTRPPRLRRIY
                     FGTLQAILLLTLPILELTPILPGVEYMYTISDERHWLLFSPLIALSFIILMALQIAALK
                     WLIAGRVKPGSCRLDSHRYLKLWYVDKLMALSLDIIRPLYATLYLLPWYCLLGAKLGWQ
                     AEISTPSSLVPDLVNIGSESFIADGVVMGVPRVERGQMYLQSIQIGKRAFIGNSALLPA
                     GSIIGDDTLIGCMSVPPADRTLVAQPNTSWFGSPAINLPQRQIVRNFSLESTYKPTFSK
                     VLQRLGFETVRVLFSLTCIVALSSVLIDTMIDLNDDWNEWILILMLPFLYLGFGLAATG
                     ITIIAKWSIVGRYRPTERPLWSNFVFRSELVTCIHETLAVPLLVNMLQGTPFINWYFRL
                     MGSKIGKRVYMDSTDITEFDTIWVGNDVALNSDCGLQTHLFEDRVMKISTVTIGDRCSV
                     GSSAIVLYDTVMEPDSNLGNLSMLMKGESLPAFSSWVGSPAQAYE"
     aSDomain        complement(15016..17067)
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS33100_TIGR02353.1"
                     /evalue="9.20E-199"
                     /label="HC643_RS33100_TIGR02353.1"
                     /locus_tag="HC643_RS33100"
                     /protein_end="1325"
                     /protein_start="641"
                     /score="653.9"
                     /tool="antismash"
                     /translation="LQALGLIVILFCFALQWLLPYLTYSWMQENGASNLESALVSVVAL
                     AAIIPLMLGFSIAMKWMLVGRVKPGKYLLWGNFYLRWWFVKNLLSITPLHFLSGTPLLN
                     IYYRLLGAKIGTNVYLSSVNIDVPDLVSISADSTIGYDAGLLNATVEEGWLKIGSIKIG
                     NSCFVGASSVVSANTVIEDNASLEDLSMLPPQHRIPAGEVFAGSPAAKVGVNSSKAMTR
                     PPRLRRIYFGTLQAILLLTLPILELTPILPGVEYMYTISDERHWLLFSPLIALSFIILM
                     ALQIAALKWLIAGRVKPGSCRLDSHRYLKLWYVDKLMALSLDIIRPLYATLYLLPWYCL
                     LGAKLGWQAEISTPSSLVPDLVNIGSESFIADGVVMGVPRVERGQMYLQSIQIGKRAFI
                     GNSALLPAGSIIGDDTLIGCMSVPPADRTLVAQPNTSWFGSPAINLPQRQIVRNFSLES
                     TYKPTFSKVLQRLGFETVRVLFSLTCIVALSSVLIDTMIDLNDDWNEWILILMLPFLYL
                     GFGLAATGITIIAKWSIVGRYRPTERPLWSNFVFRSELVTCIHETLAVPLLVNMLQGTP
                     FINWYFRLMGSKIGKRVYMDSTDITEFDTIWVGNDVALNSDCGLQTHLFEDRVMKISTV
                     TIGDRCSVGSSAIVLYDTVMEPDSNLGNLSMLMKGESLPAFSSWVGSPA"
     aSModule        complement(15016..18879)
                     /complete
                     /domains="nrpspksdomains_HC643_RS33100_AMP-binding.1"
                     /domains="nrpspksdomains_HC643_RS33100_PCP.1"
                     /domains="nrpspksdomains_HC643_RS33100_TIGR02353.1"
                     /locus_tags="HC643_RS33100"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(17146..17355)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS33100_PCP.1"
                     /evalue="3.60E-16"
                     /label="HC643_RS33100_PCP.1"
                     /locus_tag="HC643_RS33100"
                     /protein_end="615"
                     /protein_start="545"
                     /score="51.1"
                     /tool="antismash"
                     /translation="ESAIAKIWQNLFPYTKISVDDDFFLDLGGHSLLAANLVSQLREQR
                     EFAHVSMLNVYQCPTIAKLAAQLKE"
     CDS_motif       complement(17674..17739)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HC643_RS33100_0004"
                     /evalue="6.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="HC643_RS33100"
                     /protein_end="439"
                     /protein_start="417"
                     /score="37.4"
                     /tool="antismash"
                     /translation="YLGRIDTQVKIRGYRIELTEIE"
     aSDomain        complement(17704..18879)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS33100_AMP-binding.1"
                     /evalue="2.70E-106"
                     /label="HC643_RS33100_AMP-binding.1"
                     /locus_tag="HC643_RS33100"
                     /protein_end="429"
                     /protein_start="37"
                     /score="347.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FERRCDAQPDAIALICDKEHLSYAELDTQANKLANYFLRQGLGSG
                     NRIGILLERSINTYVTLLAILKCGAAFVPLDPSFPQDRIGFIAENASLDLLVTSTAFSS
                     ISTCTSCKVLVLDTVVAAIAIQPATRIAIPDTADELCYIIYTSGSTGRPKGVAVNHSNI
                     CNFLTVCTPIYGVCARDRVYQGMIIAFDFSIEEIWPTFIVGATLVAGPTNHQRLGSELT
                     DFLIEQAITVMYCVPTLLATIDRDVPLLRTLIVGGEACPQYLVQRWSRESRRILNTYGP
                     TETTVTALWTELLPNRAVTIGRPLPTYSVYILDEELHPVPVGEAGEICIGGIGVAQGYV
                     NLPEQTSAKFICDPYEQNRPQAKLYRTGDLGRVTLDGEIEYLGRIDTQVKIR"
     CDS_motif       complement(17830..17919)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HC643_RS33100_0003"
                     /evalue="1.30E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="HC643_RS33100"
                     /protein_end="387"
                     /protein_start="357"
                     /score="43.1"
                     /tool="antismash"
                     /translation="PVGEAGEICIGGIGVAQGYVNLPEQTSAKF"
     CDS_motif       complement(18400..18459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HC643_RS33100_0002"
                     /evalue="9.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="HC643_RS33100"
                     /protein_end="197"
                     /protein_start="177"
                     /score="30.5"
                     /tool="antismash"
                     /translation="CYIIYTSGSTGRPKGVAVNH"
     CDS_motif       complement(18652..18693)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HC643_RS33100_0001"
                     /evalue="2.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="HC643_RS33100"
                     /protein_end="113"
                     /protein_start="99"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LAILKCGAAFVPLD"
     gene            complement(19413..19790)
                     /locus_tag="HC643_RS41730"
     CDS             complement(19413..19790)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS41730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237266000.1"
                     /transl_table=11
                     /translation="MSNISSFHELSDRLQLSSTHPSNHCLQNLQLRFPVVGDKALIDLI
                     NGIQVSKDIIRYRKNRGWIGQLFDKLDGSDRITELKQRGYEDAKRCLMPIIKTFKTVQD
                     QRDSHNSLVNSTQHLLNDPPL"
     gene            complement(19904..20482)
                     /locus_tag="HC643_RS33110"
                     /old_locus_tag="DA73_0400033055"
     CDS             complement(19904..20482)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS33110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400033055"
                     /product="hypothetical protein"
                     /protein_id="WP_038080415.1"
                     /transl_table=11
                     /translation="MIVLDFTQLKTEASEKVKKEVQKIIKLRGVETLYELINKVDRRRE
                     GDMSTEQVKQFVAAEFGIGEASERERVFETSARRAFTSANFLMELQRNPDVLITHMKTV
                     NALAQEVFAMDWEEELEETTTEDLQRKAERLWKKSGFDLFLKRSISALMEKAAPRCIKS
                     ALNIAHSYLTELSNDVQLRNSAERPEKTN"
     gene            20746..21108
                     /locus_tag="HC643_RS33115"
                     /old_locus_tag="DA73_0400033060"
     CDS             20746..21108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015215440.1"
                     /locus_tag="HC643_RS33115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033060"
                     /product="hypothetical protein"
                     /protein_id="WP_038080413.1"
                     /transl_table=11
                     /translation="MTTVAILPIYDASGQKSYRAVAGDKYSIGKTAGQALDALTAQLGE
                     NEFSALLLLQSFHPDQFFGIEQQKRLSELMDMWRTARDEGLELSHQLQQELDNLVEAEL
                     KAATARTASLLQQQSQ"
     gene            21105..21506
                     /locus_tag="HC643_RS33120"
                     /old_locus_tag="DA73_0400033065"
     CDS             21105..21506
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019495918.1"
                     /locus_tag="HC643_RS33120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033065"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_038080411.1"
                     /transl_table=11
                     /translation="MNPKYTLVSKRAGHRCEYCHAPELVFNLPFEVEHIIPLSKQGTDS
                     EENLALACRSCNLHKSNRTSGVDPDSNTEVRLFHPRQDQWDDHFQVDATSGMIVGITAI
                     GRTSVNSLEMNSQPQVTARQLWIRLGLFP"
     gene            complement(21634..22932)
                     /locus_tag="HC643_RS33125"
                     /old_locus_tag="DA73_0400033070"
     CDS             complement(21634..22932)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS33125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400033070"
                     /product="hypothetical protein"
                     /protein_id="WP_038080409.1"
                     /transl_table=11
                     /translation="MNSTKKVFSYSLLSLLLFNNILTFHQKAIGSQSITDKPNLEKSLL
                     EEQNRIAQGQKRICLRSFCIDKSSFTETFLAKQIRVLVEQNAPVTANSNNLYPLVSSLP
                     GGSFRPNILDLEGASPKQILPAGDYVIPVKVYSLQRVASSPNGHRYLLGRYGGSRKEVL
                     AALNRSAASSDVSQKDLQNLSWAVQAGASYKDMPAEMQALVNKLIPQYRSALKPGWWEE
                     IEQLWNQSSQALHLHSLQEFLTRNLGDTGRSLFAMKQVRDRLVAKGGNWRNLADLFLIN
                     DGTAGAGNVLETPWSQVGEGVYARFVTEGNANDTGLLQLRIMDGKVAQKGMTNGNKGIP
                     LLPIIARAMTVYELYQIITTLVALPEGNKNIQPLTMSPDLFSVTKDLVEIGIKFCERRS
                     APRGRLLKAMNILCSIAGETPRITKLKVKEFHH"
     gene            23292..24080
                     /locus_tag="HC643_RS33130"
                     /old_locus_tag="DA73_0400033075"
     CDS             23292..24080
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019494538.1"
                     /locus_tag="HC643_RS33130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033075"
                     /product="hypothetical protein"
                     /protein_id="WP_038080406.1"
                     /transl_table=11
                     /translation="MFLLPGRNFILFFATCLCLLGVSSLQIPRMQKLLHTNKTVSVKTL
                     QRELDLERTRLNLIKKIPSFGYDNVIANFAYLWFLQYFGDDEVRSKTGYNLSPEYFEII
                     LARDPRFINAYLGLSTSTSMYAAMPEFSIKLMEKGLKSLSPFAPTKSYYVWRYKGIDEL
                     LFLGQALKARQSFEKSADWASYHSDEESQHARAISKKTAEFLERNPDSTYARIATWVMV
                     LNNQVDKKTRQRAILEIKALGGDVTENPDGTHKIKLPKKD"
     gene            24149..24973
                     /locus_tag="HC643_RS33135"
                     /old_locus_tag="DA73_0400033080"
     CDS             24149..24973
                     /NRPS_PKS="Domain: Aminotran_4 (48-259). E-value: 2.9e-34.
                     Score: 110.8. Matches aSDomain:
                     nrpspksdomains_HC643_RS33135_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017320406.1"
                     /locus_tag="HC643_RS33135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033080"
                     /product="aminotransferase class IV"
                     /protein_id="WP_038073247.1"
                     /transl_table=11
                     /translation="MKIYWYNGQLIESPTIELAIDEPGLLYGATVFTTLRVYDRSLESR
                     LTHWRAHCDRLKSSLESFGWQLPSEERLRQGALSLAAHFPVLRITVFPDGREWIIGRDL
                     PEGLIEKQSHGILAVLAKPEFSRCLPDRKNGNYLGAWLAKSIAQQSNAQEAILVDVQGN
                     WLETSTGNLWGWLDGSWWTPPATGEILPGIMRGELVKWLRQEGLVVREEPWTPNLVRKF
                     EALAYSNSVVETVPVHTVSSPLGKLEYNPHHPCFQQLRMFFISTIGVKFGIT"
     aSDomain        24293..24925
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS33135_Aminotran_4.1"
                     /evalue="2.90E-34"
                     /label="HC643_RS33135_Aminotran_4.1"
                     /locus_tag="HC643_RS33135"
                     /protein_end="259"
                     /protein_start="48"
                     /score="110.8"
                     /tool="antismash"
                     /translation="WRAHCDRLKSSLESFGWQLPSEERLRQGALSLAAHFPVLRITVFP
                     DGREWIIGRDLPEGLIEKQSHGILAVLAKPEFSRCLPDRKNGNYLGAWLAKSIAQQSNA
                     QEAILVDVQGNWLETSTGNLWGWLDGSWWTPPATGEILPGIMRGELVKWLRQEGLVVRE
                     EPWTPNLVRKFEALAYSNSVVETVPVHTVSSPLGKLEYNPHHPCFQQL"
     gene            25056..26900
                     /gene="ftsH3"
                     /locus_tag="HC643_RS33140"
                     /old_locus_tag="DA73_0400033085"
     CDS             25056..26900
                     /EC_number="3.4.24.-"
                     /codon_start=1
                     /gene="ftsH3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079544.1"
                     /locus_tag="HC643_RS33140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033085"
                     /product="ATP-dependent zinc metalloprotease FtsH3"
                     /protein_id="WP_038073243.1"
                     /transl_table=11
                     /translation="MNNKRWRNAGLYALLFIVVIALGTAFFDKQPQSRETWRYSQFIQE
                     VQNGNVEKVSLSADRSTALVMTKNDTNKKLVTLVNDPDLINTLTQYKVDITVLPQTDEG
                     FWFKALSSLFFPVLLLVGLFFLLRRAQNGPGSQAMNFGKSRARVQMEPQTQVTFNDVAG
                     IDQAKLELNEVVDFLKNADRFTAVGAKIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFS
                     ISGSEFVEMFVGVGASRVRDLFEQAKANAPCIVFIDEIDAVGRQRGAGLGGGNDEREQT
                     LNQLLTEMDGFEGNTGIIIIAATNRPDVLDAALLRPGRFDRQVVVDRPDYAGRVEILKV
                     HARGKTLSKDVDLERIARRTPGFTGADLSNLLNEAAILAARRNLSEISMDEINDAIDRV
                     LAGPEKKDRVMSEKRKTLVAYHEAGHALVGALMPDYDPVQKISIIPRGRAGGLTWFTPS
                     EDRMDTGLYSRAYLENQMAVALGGRIAEELIFGEEEVTTGASNDLQQVARVARQMVTRF
                     GMSDRLGPVALGRQQGNMFLGRDIMSERDFSEETAAAIDEEVRQLVETAYRRAKEVLEN
                     NRHILDKLAEMLVEKETVDAEELQDVLASNDVKTATFA"
     gene            complement(27745..29343)
                     /locus_tag="HC643_RS33145"
                     /old_locus_tag="DA73_0400033090"
     CDS             complement(27745..29343)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013739.4"
                     /locus_tag="HC643_RS33145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033090"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_038073434.1"
                     /sec_met_domain="DAO (E-value: 1.2e-06, bitscore: 27.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRSALMASLRRAYKITRASLKTGIRADEIADIVRDKMTRRRLIY
                     GGLGLASAMSAMMWDGERSSAAFAKLPKVLVVGAGIAGLVAAYRLSQAGVPVDIIEARN
                     RVGGRIHTLHNVADLSIPVDLGGEFIDTHHTSLRNLAKELGLEIVDLYAIDSNLTEGIS
                     YYDGSLISEKEIQQWLPPLVQKIERDLAAFGKTPVNYRTKNQLAIQLDNISITQYLEEA
                     KTHPILKAIIEKAYTSLYGQETEIQSSLNMLLFIGTDANSFDPIEESDERYQIVGGNDR
                     IILSLSQFLKNSIELETELEAIATQSDGRYRVSLRSGNRSVERIYERVLLALPFSTLRN
                     VSLNVDLPDLKKKAILELGYGNNAKLITAYQERIWRTRYKSTGFVSTDLNFQTIWESSH
                     YHKGSSGLLTNFTGGQKSLPLGLNSPEIQAQKLLSQLENIFPGIGSMYRGQPVCAYWRR
                     EPYTRGSYACYLVGQWTTIAGVEQQRVGNLFFAGEHCSQLFQGYMEGGCRTGEMSAADI
                     LRSMGLKKRVSVTEH"
     gene            complement(29399..29998)
                     /locus_tag="HC643_RS33150"
                     /old_locus_tag="DA73_0400033095"
     CDS             complement(29399..29998)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015128565.1"
                     /locus_tag="HC643_RS33150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033095"
                     /product="arsinothricin resistance N-acetyltransferase
                     ArsN1 family B"
                     /protein_id="WP_038073431.1"
                     /transl_table=11
                     /translation="MKATIRLANENDAFQMLSIYAPIVRETPTSFEVEPPSEAEFKQRI
                     KDYQKRLPWLVCELDGEILGYAYANPHRSRAAYQWSVESSVYVAAKHRKKSVGKALYAS
                     LFKVLQVQGFYNVFAGIVLPNPASIALHEAFGFTLVGVYRAVGYKLGQWYDVGWWQLSL
                     QHERSELVNPPLSWQEVEKLPLWNEALRSGLNFLRV"
     gene            complement(30293..30574)
                     /locus_tag="HC643_RS33155"
                     /old_locus_tag="DA73_0400033100"
     CDS             complement(30293..30574)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020265.4"
                     /locus_tag="HC643_RS33155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033100"
                     /product="DUF1778 domain-containing protein"
                     /protein_id="WP_038073428.1"
                     /transl_table=11
                     /translation="MFEVAAATPKETRLSIRATEPEKAILAEAARIRHTNVSKFVLQAS
                     LDAANAILMNQTEFRLPPDRWEAFCERLDAPPKVVRALQQLFSEPEQF"
     gene            complement(30722..31420)
                     /locus_tag="HC643_RS33160"
                     /old_locus_tag="DA73_0400033105"
     CDS             complement(30722..31420)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016867507.1"
                     /locus_tag="HC643_RS33160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033105"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_038073426.1"
                     /transl_table=11
                     /translation="MTDSILQEQIAYYSARANEYDEWFYRIGRYDRGEELNQRWFNEAG
                     VIRNALYQIGNVERVLELACGTGIWTQELLKIGQKITALDASSEVIAIARSKIGAANVE
                     YQQIDLFNWEPNTEYDLVFFSFWLSHVPPNLVDSFLKKVYKATHRGGQIFIVDSRFEST
                     STAKNHVLENDGNIYINRKLNDDQEFKIVKIFYSPEQLRGKLIQAGFEVDVKVTDNYFI
                     YASGSKSETH"
     misc_feature    31522..31537
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.6"
                     /tool="antismash"
     gene            complement(31765..32451)
                     /locus_tag="HC643_RS33165"
                     /old_locus_tag="DA73_0400033110"
     CDS             complement(31765..32451)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017743971.1"
                     /locus_tag="HC643_RS33165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033110"
                     /product="PHP domain-containing protein"
                     /protein_id="WP_038073590.1"
                     /transl_table=11
                     /translation="MTVKVAEVSTSREQLKYIFQSINALSCPMSFNFHMHTVHSDGKLQ
                     PSALMEQAVTIGLKGLAITDHHSISGYQAAQNWLEQWRWNNPGANVPQLWTGVEINANL
                     LNTEVHILGYAFDIEQPSIKPYIQRKATTGEHHQAANVISAIHEAGGLAVLAHPARYRR
                     SHFDLIPAAADAGIDGVESFYAYNNPNPWKPSARESEQVQQLASEYSLFNSCGTDTHGL
                     SLLHRL"
     gene            complement(32779..33807)
                     /gene="purM"
                     /locus_tag="HC643_RS33170"
                     /old_locus_tag="DA73_0400033115"
     CDS             complement(32779..33807)
                     /EC_number="6.3.3.1"
                     /GO_function="GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="purM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017743972.1"
                     /locus_tag="HC643_RS33170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400033115"
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="WP_038073422.1"
                     /transl_table=11
                     /translation="MDYKEAGVDVEAGREFVNQIRNLVHSTFRPEVIGGLGGFSGCFQL
                     PTGYREPVLVSGTDGVGTKLKIAQAVNRHDTIGIDLVAMCVNDVLTSGAEPLFFLDYLA
                     TSHLEKEQLTEVVAGIASGCKQAGCSLLGGETAEMPGFYQVGEYDLAGFCVGIVEKSQM
                     LDGSQVRVGDVAIALASAGVHSNGFSLVRKIVSDKGFSWSDRPDRLGGQTLGEIFLTPT
                     YIYVESVLAARKAGLEIHGMAHITGGGLPENLPRCLGKGQAIKIDPKSWSIPPIFQWLA
                     EEGSVNAQAMYNTFNMGIGFVLLVPPHQVEPAMTHFALQNITARTIGEVIPGSGELLGL
                     PI"
ORIGIN
        1 ggtaccagac tcactcattg cttacaagcc aacactagat ataaacgcag gggcgcatca
       61 gtttaaatac cgcccggact ttagcaactt gtcgattaca gaacaaacag gttgtatcat
      121 tttctctcgt ccctgtaatc ccacaggtaa tgtcttgact gatgatgagg tgaagaaaat
      181 tgctgccctc gctgcgcctt atgatgtgcc agtgtttatt gactcagcat acggtcctcc
      241 tttcccagca ttaaacttca ctgaattgac gccgattttt ggggataaca ttgttcactg
      301 catgagttta tcgaaagcag ggttaccagg agaacgtgtt gggattgcta tcggtgatga
      361 aaaaattatt caagttttgg aatgcttcca aaccaatgcc tgtctccatg catcaaggta
      421 cggacaggca attgctgcga tcgccattaa ctctggtgcg ctagcaggaa tttctacttc
      481 tgtgattcgt cccttttacc aaaacaagtt tactgttttg gaaagtactt tgaacaagtt
      541 tatgcccgaa catttacctt ggttcctcca tcgaggggaa ggggcgatat ttgcttggtt
      601 gtggttgcaa gatttaccca tgacagattg ggaattgtat caagaactga aaaaggtggg
      661 tgttatagtt gtacctggaa gtaccttttt ccccggcttg caggaggaat gggtacacaa
      721 gcaacagtgt gtacgcatta gcttgactgg tagcaatgag gaaattgcga ctggtatgga
      781 gcgtttggca aaggttgtac aacagattta tcagacatcc gctgtgagtg tttgaatgaa
      841 ctacgaagac gcgaagagcg caaaaaagga catgaagcag aaggggagac ggggacaagg
      901 aggtaaggga accggaggac aaggggacaa gaggacaagg ggacaatcta cttctccctc
      961 atccccttct ctccccatcc ccccctctcc ccatcccccc ctctccccat ctccccctca
     1021 attccctgat ggttggatag agattggtac aattgttgct gcccagggct tgcatggtga
     1081 agttcgcgtg ttatcgaact cggattttcc agaacgattt gaggttcctg gaaaacgctg
     1141 gttgtggtgt ccggcgcaaa tggaacccca acccattgag ttactggcgg ggcgcaatgt
     1201 cgaagggaaa aatttgtata ttgttaagtt atctggggtt ggggatcgca atcgggctga
     1261 ggagttgcgg ggttataagt tactggtgtt ggagagcgat cgcccccaat tgggggaaga
     1321 tgagtatcat gtcttggatt tgattggttt gtcagtctat atccaagaat ctggagagtt
     1381 tgtaggaacg attgtagatt tgctttctgc agggcatgac ctgatagagg tacggctgga
     1441 ttcttcaagg gataaggcac aaagaactgt tttgattcct tttgtcacgg caattgtgcc
     1501 tattgtggat ttagaaggtg gtcgtgttga gattactccg ccatcaggat tgctggaaat
     1561 ttacagttag tttggagcgg acagttttcc tgagtattta caatgcttat tttagtcaaa
     1621 attatctgac tttaggcaac aaatacacag tttctttgag ataattgttt aaaacggatg
     1681 ttagcatata taaatggata taatcatcaa aaaatttgat gaaaactatc gatacgtgtc
     1741 attagtttta ataggtttgg agttgggctg aaagcaccgt aaaaatcact tacaactcaa
     1801 caaatttagc aacaataatg acatgaacga ctagtggtac gtttcataat ttgccccgat
     1861 ccccgacttc tataagaaat cagcgatcta gcagcttatt aattactttt attagagtaa
     1921 aaatttttat tttttgcaat ctatttataa tgagatcttt ttataagaaa aatttattta
     1981 atccaattac cctatttctt aatcgagatt taatctaacc caaggcagta ctggagaacc
     2041 catgtgttaa acctctatca aaaggcagaa cgaagtggga aaaataagat tttgacaatt
     2101 aaaaaattaa tgatgatttt aaggtgaaat aaaatatttg ttacaaaact agcaagaatg
     2161 gacttcattt gttagccttt cacaagaagt aattaaacct agtttatatg gttttgttgc
     2221 tatgtaaaaa ataacccact cagtctgatg gcttccccaa aaggagatac tacatcagac
     2281 atacctacct tacttaggtc aggttcgtat aaccgcaagt tttatagtat tgtgtcatcg
     2341 gtatgatgat ccctatatcg gtggcaaata aacttacacg tgggaatctg caaacatcct
     2401 tttgtgaagg agttttcata tgactttagc gagccgtccg cagacaaagc cgttatcaga
     2461 tgacgaactg cagaagatga acgcctattg gcgtgcagcg aattatctct cggtgggaca
     2521 aatctatttg ctggacaatc cactgctgaa agaaccactg aaagtagaac atatcaaacc
     2581 cagacttttg ggacactggg gaacaactcc cggtctgaac tttatctacg ttcacctcaa
     2641 ccggattatt aaaaagtacg atctggacat gatttacatc gcaggtcccg gtcatggcgg
     2701 tcctggaata gttgcgaata cttatttaga agggacttac agcaagtatt accccaatgt
     2761 atctcaagat gctgagggaa taaaaaaact tttcaaacag ttctccttcc ccggcgggat
     2821 cggtagccac tgtacgccgg aagttcccgg ttctattcat gaaggcggtg aattgggtta
     2881 ttccctcgtt cacgcttatg gtgctgcttt tgataacccg gacctcatcg ttgcgtgtgt
     2941 gattggggat ggcgaagccg aaactgcagc cctatctgca agttggcact ccaacaagtt
     3001 tcttaacccc gtccgtgatg gtgcggtcat tccaattctt cacctcaatg gttataaaat
     3061 tgctaaccca acagtgctat cacgcttgag ccacaaagag ttagaaagcc tatttatagg
     3121 ttatggctac aagccttact ttgtggaagg ttccgatccc gaaaccatgc accagttgat
     3181 ggcagctact ttagaaacca tcactcacga aattaaagaa attcaggaag atgttcggaa
     3241 taatggcttc tcccaacgcc cgcaatggcc catgattgtt ttgagaagcc ccaaagggtg
     3301 gacgggtccc aaggaagttg acggtaagaa gacagaagat tactggcgat cgcaccaagt
     3361 tccttttggc gagttacaag gcaatccaga tcacttgcga ctcttagaag agtggttgag
     3421 aagttacaaa ccagaagaac tttttgatga aaatggtaca ccgatcgcag aactgttaga
     3481 attacctccc aaaggacacc gacgcatgag cgataaccct cacgctaatg gtggtctttt
     3541 actgcgcgat ttgaaaatgc ctgacttccg cgattatgcg atcgatgtta ccgaagttgg
     3601 cagaacaatt ggtgaagcca caaaggtatc tggaaagttt ttgcgagatg tgatgaaacg
     3661 caacttagat agcgctaact tccgcatctt tggtcctgac gaaaccaaat caaatcgctt
     3721 agatgctatt tttgaagtga cagaccggac ttggctagct gagaagtatc cctatgatga
     3781 tgccctatca cccgatggta gaatcatgga gattctgagc gaaacaacgt gtcagggttg
     3841 gttggaagga taccttttga cgggtcgcca cgggttcttc tcctgctacg aggcgtttat
     3901 ccatatcgta gactccatgt ttaaccagca cgccaagtgg cttgacacct gccatcatat
     3961 tccttggcgc agaccaattg cttctctcaa ttacctgctc acatctcacg tttggcgtca
     4021 agaccataac ggtttctctc accaagaccc cggttttctt gacctagtgg tcaacaagaa
     4081 agcaaatgta attcggatat atttaccacc tgatgccaat tgcttgttgt ctgtaaccga
     4141 ccattgcttg cgaagccgca actatatcaa cgtcatcgtc gctggaaaac aacccgcatt
     4201 gcaatacctt cccatggatg cggcgatcaa acactgcacc aaaggcttaa gtatttggga
     4261 ttgggcaagt aacgaccaag gtggagaacc agacgtagtg atggcgtgtg cgggagatat
     4321 tcctacacta gaaaccttag cagctgtaga cattctgcgg caaaacttcc ccgatctcaa
     4381 ggtacgggta gtgaacgttg tagatttaat gaaactccag cccgcaagcg aacatcccca
     4441 cggacttagc gacgctgact ttgacagcat tttcacaact gacaaaccaa ttatctttgc
     4501 cttccacggt tatccttggt tgattcaccg tttaagctac cgtcgccaga accatgcaaa
     4561 cctccacgta aggggttaca aggaagaagg aacaacaact acaccttttg acatggtagt
     4621 cctcaacgat ttagaccgct tccacctagc tatggacgcc attaatcgcg taccacaact
     4681 gggatacaaa gcagcttacg tgaagcaggc actgcaagac aagctcattg agcacaaaca
     4741 ctacattcac aagtacggcg aagatatgcc agaaattcgt gaatggaagt ggccgtacta
     4801 gaggaatttg ttagtggttg gtggtttttt taacaactag ccattaacga ctaacaacta
     4861 accctccctt acaaatctta aaagatgtca attaaacttg gctttcgcta acatacattg
     4921 gcaggattgg gtcaagaagg gactgaggat tcggacaaat tcccaatccc taactcccaa
     4981 tcccaatccc gaaacaggag gtttcatctt gagtaagctg aaagttggca tcaatggatt
     5041 tggtcgtatt gggcgacttg tgtttcgtgc tggtatcgat aaccccaaca ttgagtttgt
     5101 tggcataaac gacctcgtac caccagataa cttggcatac ctgttgaagt acgattcaac
     5161 tcacggtagt tataagggtc aggtcgaggc aaaggaagat ggcattgttg tcaatggacg
     5221 tttcattcct tgcgtgtcgg ttcgtaaccc tgcagagtta ccttggggta aattaggtgc
     5281 agattatgtt gtggaatcta cgggtttatt tactaccttt gaaggtgctg caaaccacct
     5341 gcaagcagga gccaagagag ttataatctc tgctcccact aaagatccgg agaaagttcc
     5401 taccctatta gtaggtgtaa accatcacct attcgatcca gcaaaagata ctgttgtctc
     5461 caatgctagt tgtactacga actgtttagc ccccgttgct aaagtactga atgacaaatt
     5521 tggattaacc gaagggttaa tgacgacagt tcatgctatg actgcgaccc agcccaccgt
     5581 agacggtccg agtaaaaagg actggagggg aggacgaggt gctgctcaga acatcattcc
     5641 ttcttctaca ggtgcagcaa aagcagtcgc actggtttta ccagaattga aaggcaagtt
     5701 aaccggtatg gcattccgag ttcctactcc cgatgtctct gttgttgatt tgacattcaa
     5761 aactttatca gctaccagtt acaaagaaat ctgtgctgct atgaaagagg cttctgaagg
     5821 cgctctaaaa ggaattttag gctacacgga agacgaagtg gtttctacag attttcaggg
     5881 cgattcccat tccagtattt ttgatgctgg tgctgggatc gaattgaact ctaatttctt
     5941 taaggttgtt gcttggtacg acaacgagtg gggttactca aatcgtgtca ttgacttgat
     6001 gttggctatg gcacaaaaag aaggtttgtt agaacggact gctgtagcag tttaacaagc
     6061 cacagctatc agttatcacc cttgctggat aactgatagc tgtttgcaat tctatgaatt
     6121 ttacaaatat ttacatactt agctgtataa aacaagttcg gaaacctgaa attgaaccta
     6181 caatgtaggc ggttattaaa gatgaggata catagaataa tatttttggc aagagtaata
     6241 ttacttgatt gatttaatgt caaaaatttg cattaattta gtcagtactg aagttgattt
     6301 ctctcaacct tatattttct cttgaacaga ggtcttcaag aaaggtttct cccctaaaaa
     6361 aataggggat gaggacaaca gagaattttt atggctggaa ttcaaaaata ctttattatg
     6421 cgaagaacca aaattatttg tactgtcgga cctgctacat ctacaccaga aagactccaa
     6481 tctttggtgg atgcaggtat gaatgtggca agactaaact tctctcatgg agaacacgcc
     6541 tttcacggtc aaaccatcaa atatctcagg caaattagta gtgcaacaca gaagcctctt
     6601 gctctcatgc aagatttgtg cggtcccaaa attcgtttgg gagttttacc acaagaaggg
     6661 attactgtag aggcgggtca agaagtaact tttgtgctgc aaaaagaagg caaaagtgct
     6721 gacgaaatcc ccctaccatt gccaactctg tttgcaatgg ttcgacgcgg cgaaccaatt
     6781 ctcattaatg atggtcgcat caaagtgatt gtttgcgatc gcgatgcgga tcggattcga
     6841 gcacaggtca tcattggcgg tttgatatcc agtaacaaag gcgtaaactt accagaaacg
     6901 cgtttacctg taacctccat tacagaaaaa gacttaagcg atttgcgttt tgggattcaa
     6961 ttaggtgtag atttagtggc agtatccttt gtgcgatcgc cccaagactt agaaccagca
     7021 caaaggatga ttgaaggagc aaatgcaaat attcgcatca ttgccaaaat tgaaagacga
     7081 gaagcagtag agaatattga tgaaattata gaagtcgctg acggaattat ggtagctcgt
     7141 ggcgatctcg gagtagaaat gcccatcgag caagtacccc taattcaaaa agatattatt
     7201 ctccgatgta accgtgcggg taaacccgtc attaccgcca cacaaatgtt ggaatcgatg
     7261 attagcgccc ccgatcccac ccgtgcagaa gtcaccgatg ttgccaactc aattttagat
     7321 gggactgatg cagtcatgct gtcaggagaa actgctgtag gacaataccc ggtagcagcc
     7381 gtcaaaatga tgcacagtgt tgctgtaaga acggaaaatt ctctcaaaga aggagcacgt
     7441 caagccttat ggaattacga tgcgggaagt ttgagtgtta ctgaatcttt agccgaagcc
     7501 gtttgtcgca tcgcctatga aacaggtgct aaagcaattg tttgtcactc ttcaagtggc
     7561 aatacagcaa ggctcatttc taaataccgt ccaacaactc caattcttgc tctgacccct
     7621 tgcgacaccc cttaccgtca gctagcactt tcttggggta tagaaccttt actcatccaa
     7681 tccgtttata ccgccgaaga gatgttgata aatgtggaaa aaactctttt agagacggag
     7741 ctgattcaac aaggggatag agtcgtcatt acctcaggcg tacccattgg taagtcagga
     7801 actacaagct tagtgaaagt gcataccata ggacagccta tttcagctta agcagctatc
     7861 atttgcgtac agcataacgg atgaaaaaag gattggcgat tgatttccca gttaccaatc
     7921 tccagtcccc agtcgctgat taaagaaagt caaaaatgta gaagaacaat tggttcgttg
     7981 accgcgatta gaaatcgccg ctacacaaac gaagtccctc ccttgtatct caggagcgga
     8041 gacgctatgt gcaaggcaga cgctctcgtc gctatcgcga cacgcttcgc gatgcctttg
     8101 ggctataccc gccagagcta tacgccagtt cccagggcgt gggaaacccg cctactttct
     8161 ctggactcac cacctaatgg gacttaaata tgaactccgc cgatgcggac ttggtttgta
     8221 tagcttcaga atagaattct gaaggcaatt ggcactcttt gggatgctcc cgtctttatg
     8281 tatttagagc gctaaaggca attttaatgt taaactgaat tttagtatta aaaaaataat
     8341 gtaagatgtc taaatcaatt agcattactg actcaagaaa tgaacttctt caattacccg
     8401 aacagttagg taatgaacct gtaatagtta ctaatcaagg tttgccagtt atggtagcta
     8461 ttagctatga gcaatatatt tctatgttag aaactatgga aattttatcc gatccagaat
     8521 ttaaagaaca attaatagct ggaattcaag aagaccgaga aggtcaaagg gtaagttggg
     8581 cagaagccat gaaagaatta gaatggtaaa tgatggaata tgaaattgag tttattcctt
     8641 tagctattga attactgaaa aaggttaaag accaaagaga acaaaaagca ctccgtcaaa
     8701 aaattgaaaa actgaaaata gaaccagaaa aacagggtaa agctcttaca ggtcagtttc
     8761 aaggctatcg tagtgtaagg gcagttggtc aacgctatcg tattgtttat cgtgtcgatc
     8821 gaaatagaat tattgttgta attgtaggtg ttggaatgcg tcgggaaggt gagagacagg
     8881 atatttatgc tattttagaa aatgagttag acgaagaata aagagattat ttcacacccc
     8941 tttaatttta ctcctgattt cacacctatc tttgactgga gttcccagga gcttttgatt
     9001 tctctcctct tccctctatg tactcttgga agtactacgt taaataatta catacgtaga
     9061 gagagtacca aaggttatat tatcagaatt ggaatgacat taaccacctt agcagggcta
     9121 agaatgccta aggcggctcc tctcaacgct cataaagact cgtaggaggg tggtttccct
     9181 acacgtagtt caaaaaccaa atcagattcc gggataattc caaactgggc tattgatgac
     9241 agatattgtg ctctacctta cagtatttgg gctcgccggc ttgtcttttc tatttgcggt
     9301 aagcagttac gagcaacaaa atcttaaaaa aaacaaacaa aatggggatt tccaaacaat
     9361 actattgacc attgactaag aactatctaa tttttgaggt ttgtatctta agttaattca
     9421 agctattgcg gaagtttata gatttgagat gaagttccaa ttgccaacaa gtttgataga
     9481 gattgagaac gatgtcacct gttctcagtg caatctaaga tggtaagagg tggataggta
     9541 ctgttaagac gagtaacgtt gtttttgtgc aataagccgt gtacggctcg cgccaagggc
     9601 gatagccggg tacggcttgc gccgaagcga tcgcaaacct aataggagga tatatgtcta
     9661 aaaacttact ggagcagtta agagagttta cggttgtcgt tgctgacaca ggggatatcc
     9721 aagcaattga aaagtttaag ccacaagacg ctaccacaaa cccttcccta attactgctg
     9781 cagcacaaat gccagagtat cgggaaatcg tagacgagac tctactccaa gcccaaaaag
     9841 atgcaggacg gggagcaagt caaaaggatg tagctgcttt agcatttgac cgtttggcag
     9901 tgtcctttgg cttgaaaatt ttacaaatta ttccgggtcg ggtgtctaca gaagttgatg
     9961 cacgcctttc ctacgataca gaagcgactg ttgccaaagc aagggattta attgctcagt
    10021 atcaagcagc tggaatttct cgcgatcgcg tcctgattaa aattgctgct acctgggaag
    10081 gaattcgcgc tgcggaaatt ctagaaaaag aaggtataca ttgtaacttg actttgctgt
    10141 ttggtcttca tcaagcgatc gcttgtgcgg aagcgggtgt tactttgatt tccccgtttg
    10201 tgggtcgcat tctcgactgg tacaaaaaag aaaccggacg cgatagttac ccttctactg
    10261 aagacccagg agtcttatct gttaccaaaa tttacaacta ctacaaaaaa tttggttaca
    10321 aaacagaagt catgggcgct agtttccgca acattgggga aattatagaa cttgctggct
    10381 ctgacttgct aaccatttct ccagcgctat taggtgagtt aaaagcgacg ataggagact
    10441 tacctcgcaa acttgaaccg agcaaagcag caacatcgga tattgaaaaa attccgatgg
    10501 acaaagcgac cttcgacaag atgcatgcgg aagatcgcat ggcaaacgac aagctagatg
    10561 aagggatcaa gggtttcacc aaagcactag aaactttgga aacactccta gcagaaagac
    10621 tggctcgttt ggatggaaaa tcaaccctca gccatgcaac ccaagatatt ttccacgtgt
    10681 acgatctaga tggtgatggc tttatcaccc gtgaagaatg gatgggtacc gatgctgtat
    10741 tcgatgcctt agacgtaaat aaagatggca aaattacacc agaagaaatg ggtgctggtt
    10801 tgggagcagt cattcaaatg gcagaggtag caaaataaga aacgattggt ttagaaacaa
    10861 aggcagaggc taggaggcag acaagcaaga gcattctgtc tcctgccctc aaaattgtat
    10921 atcttcacct ttgcttgcca aaactagtgc ggttgccaca atttgcccat cgtgcatttc
    10981 attgtttttt caaatttttt ggctcttcag tacttgttat gctaaactaa caagtactga
    11041 agaaccaaaa ctattgccgc caagaaatag gaacctcgac tttttaagaa atcggagaga
    11101 taccaataat tctacgcaat aattaaaagc attacttggt ctcggacagc atttccggct
    11161 gctgtagcaa tatcttccca atcactatca agtagcaata cacttaataa attacgtaag
    11221 acttgggtat cattaataaa ctcttcttta tataaatcat cgcacattaa tgttgttttt
    11281 agtatgggaa ttacggtctg ttcaggtaat cgcaaacgag ataacaaacg caaacgcgca
    11341 acttcaacag cagcattttc ccctactcct aaatttcgtt cggctagcag tcgttgaatt
    11401 tcgcagttga gggaaacacg taattcagtc agccttccta ataaagctgg attttggata
    11461 aaagcaagat atgcttgatt atcccaatct aatcccgcac tgacgtcaca atctgcttcg
    11521 tcctcagctt gaattgcttg ctgtaatgac gcagagccga ataataactc tatagcttcc
    11581 gtgacagtaa tattttcttc ttccattttc ttgcttctat gaccctacta tttcatatga
    11641 caaattatca gtaccgggat ttaatttaac tttgaaaacc acattttata ccttgttaca
    11701 atcataatac tagtatgcat tgaaacacta ataaggcatt gtacgataga taagtgttgg
    11761 tcaagcacaa taatttcata attttaccga catacctctg tgtaacaatg aggatttgct
    11821 gattatgaaa atactggtac tgaacgccgg atctagcagc caaaagagtt gtttgtacga
    11881 cattgctggt gatacctttc ctcaagagcc tctcaaacca ctctgggaag caaaagtgga
    11941 ttggactcac catcaaggat ttgcagaaat tgaggttaag acagcaacgg gagcaacact
    12001 agaagaagaa attccctcaa actcccgctc tgaggttgtt gctcgtatgc tcgatacgct
    12061 gtacagcggc tctactcagg tgatcgatcg gccttcagac attaaggtgg tgggacatcg
    12121 agtggtacat ggtggagaag attaccgtga aagtgtggtg attactgagg atgtaaaagg
    12181 cgcgatcgct cgtctggcaa ccctagctcc agcacacaat ccagtcaatt tagaaggcat
    12241 agaagccatc gagcaaaatt tgggaggcat tacccaagtc gcagtttttg atactgcatt
    12301 tcacgctcaa atacctgatg cagctgcaat ctatcccggt ccctatgaat gggtagaaca
    12361 agggattcgt cgttatgggt ttcatggtat cagtcatcag tattgcactc agcgtgcggc
    12421 tcgcatcctg ggtcgggatt tagcggggtt gcggttgatt acctgtcatt tagggaacgg
    12481 ttgctcgtta gcagcagtaa aagatggtcg cagtatagac acgacaatgg gcttcacgcc
    12541 cttagatgga ttgatgatgg gtagccgttc tggagcagtc gatccgggga tcatcattca
    12601 tcttttacgg caatctgact attctgctga taagttagat aatgttttga ataaagcttc
    12661 tggtttgcgt gggatttctg gtgtgtctgg tgatatgcga cagattcgcc aagaaatttc
    12721 tcaagggaac tcccgcgctc aacttgcttt tgatgtgtat gtccatcgat tgcgatcgta
    12781 cattggtgca atgcttgcta gcttgggggg tttggatgca ttgatattta ctgcgggtgt
    12841 tggggaaaat gatgctgtac tcagggaagt cacttgtgaa gcgtttggat ttttgggttt
    12901 aaaaatagat aaagaaaaga acaagcacaa gcctgtggat actgatattt ctactccaga
    12961 ttcagcagtg agagttttgg tgattcatac agaggaagat tgggaaattg ctcgcgaatg
    13021 ttggcggttg gtaaagtagc aaactttgca aggggtaaca ataacatctt gtggtgcggg
    13081 cgtccccgct cgcacaattt atactcgatc gctcaaaaag ccagcagtta ttccaataag
    13141 caaaaatatt cccataacga agcgatacca aacaaacacc caagtgctgt gcttctctaa
    13201 ataacgaagt agaccataaa ttgcagcaaa ggcagaaaga ctagctgtaa ttagcccaat
    13261 tattaaagtt atccaaccat taagattgag tccagcttta aagagggtat gtaattctaa
    13321 tgctccggct aatacaacgg ctggtaaccc aagtaaaaat gaaaatctag cagcagtttc
    13381 tcgctccatt cctaagaata atccactcgt taaggtagaa ccagaacggg agactcctgg
    13441 aattaaagct aaagcttgac taattccaac ccaaatgcca tctttccatg ataactgatt
    13501 aaaatcacga tcgcgattgc cgattttttc cgcgattgcc agtaacaatg acataacaat
    13561 tgatgctaat ccaactacag ctaaagtgcg aaaaggagag ttacaagcat taagagtttt
    13621 tttcagcaaa agacctgaga tacaaatagg gattgtgcca actaatactc caactgcaag
    13681 gcgaaagtat cgatctagat agttttgttc tgaaatcgct cttaccgttg cacccgtcat
    13741 tttcttgagg tcgtaccaaa aataactaat tacagccgca atacttgcta actgcatggc
    13801 tgcactaaaa gcacttccag ggtctttcca tcccaacaaa gcggggataa tccgtaaatg
    13861 agctgtgcta cttattggta ataattcggt aatcccttgt acgattccca aaacaattac
    13921 cttaaaccaa cctaactcta cgaaacctaa atcgatgtcg ctcggacaag cagcagttga
    13981 taataataaa gaaagcatgg cattgtggag atagtttaaa tagaaacgat attaaggact
    14041 tccagagaaa aaatattcca ctttcttttg tggtggaggc ttctagagag acaattgtaa
    14101 gtgacgggcg aggacgcccg taccataaga tgaataattt atttcttgga catccctcag
    14161 acaataaagg aaagtgcgcg tattacctcg aaccaatcat gtgtttcaaa gagaaccgat
    14221 tgttctccat gtagttttgc tcctggataa aaggaatttt cgtaagcatc tggtggatgc
    14281 ttgtattcga cttcaagctg aaaacaatcg ggtaaaggtt tgaccggaat ttgatattgc
    14341 aatgcacttt ttacacctgc ttgaatttgc ctaacaactt cttctggatg aatgccccat
    14401 actgactcac caattccctt tttggtaata actgtttcga tgtttttgtc ataaactttt
    14461 acatcttgac atagaccaga atctccagac acaaatacga caggaacttt ttcataagca
    14521 gcagtcatcg ctactaaatg aaactcagcg atcgcttgac cattgagcag aatctggttt
    14581 aattcctcgc ttaaagtatg tgcgagggga ttactaccat atccagaccg tgaatgatag
    14641 ccaattaaaa ctaaagcagt aaaactgcta tttaattctt gaaccatgct gtaaggatgt
    14701 ccgctccatc ctctgataag ttgtgctgga taaggcaatc gataggggtc aagatttctg
    14761 gctgtatcat gagcatcttt cacgataatt tcagttgcac cagctgctat tgctccctcg
    14821 caggctgcga tgacttcacg agtcatttgc tcttgaaaga tatcttagtt ttgttgaccc
    14881 tgagtcgctt catcccagtg gctgattcca ctaattcctt caatatctgc gctaatataa
    14941 actttcatag gatatgagaa atggccgtct agctagcatc atcgtgccac acaatctctt
    15001 ttactcataa gcttgagcag gagaaccaac ccaagaggag aaagcaggca aagattcacc
    15061 tttcatcagc atggataaat tgcccaagtt ggaatctggt tccatcacag tatcgtagag
    15121 aacaattgca ctactaccta ccgaacagcg atcgccaatt gtcacagtcg atatcttcat
    15181 cacgcgatct tcaaacagat gggtttgtaa gccacaatca ctattcagtg ctacatcatt
    15241 gccaacccaa atcgtatcaa attcagtaat atctgtagaa tccatgtaaa cccgtttacc
    15301 aattttgctt cccattaagc gaaaatacca gttaatgaag ggagtgcctt gcaacatatt
    15361 taccagtaaa ggaaccgcta aagtttcatg gatacaggta accagttccg agcgaaacac
    15421 gaagttagac cacaaggggc gttctgttgg tcgataccta ccgacgatcg accatttagc
    15481 gatgattgta attcctgtgg ctgctagtcc aaaaccaaga tataggaatg gcaacatgag
    15541 tatcaatatc cattcattcc aatcatcgtt caaatcgatc attgtatcaa ttaaaactga
    15601 gctaagggcg acaatacagg taagagagaa caacactcgc actgtctcaa aacccaagcg
    15661 ttgcagtact ttactgaacg tcggtttgta ggttgattct agtgaaaaat tccggacaat
    15721 ctgccgttgt ggtaggttaa tggctggaga accgaaccag gaggtattgg gttgagcaac
    15781 taaggttcga tctgcgggag gaacagacat acagccaatg agggtgtcat caccaataat
    15841 cgaacctgcg ggaagtagag cgctgttacc aatgaaggca cgtttgccaa tctgtattga
    15901 ttgcaaatac atctgtcccc gctcaactct tggtacaccc ataaccacac catctgcgat
    15961 aaagctttcg ctgccaatat tgactaaatc gggaaccaaa gacgatggtg tagagatttc
    16021 tgcctgccat cctaactttg ctcccaacaa gcaataccaa ggcagcaggt acaacgtcgc
    16081 gtaaagcggg cgaataatat cgaggcttaa tgccatcagc ttatctacat accacagttt
    16141 taggtaacga tgactgtcta ggcgacagga accgggtttg acacgtccgg caattaacca
    16201 cttaagtgca gcaatttgca gtgccatcaa aatgataaac gataaggcaa tcaagggaga
    16261 aaacagcagc caatgtcgct catcactaat ggtgtacata tattcgactc caggaagaat
    16321 cggtgtgagt tccaaaatag gcagggtcag caacagaatt gcttggagag taccaaaata
    16381 aattcgtcgc agccgagggg gacgggtcat cgctttgctt gaattgactc caactttagc
    16441 agctggagaa ccggcaaaaa cctccccggc tggaatccgg tgctgtggag gcaacattga
    16501 taaatcttcc agactggcat tgtcttcgat aacagtgttt gcgctgacta cagaactggc
    16561 accaacaaag caactattgc caattttaat agaaccgatt ttcagccaac cctcttccac
    16621 cgtagcattt aacaatcctg catcgtagcc aatagtacta tctgcactga tgctcaccaa
    16681 gtcaggaaca tcaatattga ccgaactcag gtaaacattg gtgcctattt tagcacccag
    16741 cagtcggtag tagatattga gtaagggggt accactcaaa aaatgcaatg gtgtaatcga
    16801 tagtaagttt ttgacaaacc accagcgtaa ataaaaattg ccccagagca gatactttcc
    16861 tggcttgact cgacctacaa gcatccattt catagcaata gaaaacccaa gcattaaagg
    16921 aattattgct gctaaagcga cgacggacac taaagcggac tcaagattgc tggcaccatt
    16981 ctcctgcatc caactgtagg ttaagtaagg taacaaccac tgtaaggcaa agcaaaatag
    17041 aatcactatc agtcccaacg cttgaagagt tacgcacttt aggtagcgtc tgtggctcag
    17101 gcgatggaag caggaattcg ctggaacttt tgtggatgcg ggttgttcct ttaactgggc
    17161 agctaattta gcaatggtag ggcattggta gacattgagc atggagacgt gagcaaattc
    17221 acgttgttct cgcaattgag acactagatt ggcagccaaa agtgaatgcc ctcccagatc
    17281 gaggaagaag tcatcgtcta cagaaatttt ggtgtaggga aagaggtttt gccaaatttt
    17341 ggcgatcgcc gattcctctt ttgataagga gggcagtgca tgagactcgg tacgatgatg
    17401 gctttgcatt ctctgggttg gagcaggcaa cttcgagcga tctgccttcc cgttgggtag
    17461 cgttggtatt gcgtctaaaa tttcgatgaa cgctggcacc atataattag gtaagcgctg
    17521 gcacaacgct gtatgcaaac atttttttaa ttcttgagaa tcggtaacag gaacgcgtag
    17581 tgtaatgtag gcgaccaatt cctgaacagt cgcgttaata gacaccaaag aaacaatggc
    17641 attttcaact tctggagttt ccagcaacac tgtctcaatt tctgtcaatt caatgcggta
    17701 gcctctaatc ttaacttgag tatcaatacg tcctaaatat tcaatctcac cgtccagtgt
    17761 gactcgtccg agatcgcccg tccgatataa tttcgcttgg ggacggtttt gctcatatgg
    17821 atcgcagata aacttggcag aggtttgttc tggcaagtta acgtaacctt gggcaacccc
    17881 aataccgcca atgcagattt cccccgcttc ccctacaggg actggatgca attcctcgtc
    17941 cagaatatag acgctatatg tgggtagggg tctgccaatt gtcacggctc gattgggaag
    18001 taattccgtc cagagtgcag tgactgttgt ctcagtcgga ccgtaagtgt taagtatgcg
    18061 ccgactctct cggctccacc gctgtaccag atattgaggg caggcttcac cacctactat
    18121 taaagtccgc aataaaggta catcgcgatc gatagtagcc aatagtgtag ggacacagta
    18181 catcaccgtt atcgcctgct caatcagaaa atcggtaagc tcagagccaa ggcgttgatg
    18241 gttggttgga cctgccacta gcgttgcacc aacgataaag gtaggccaaa tttcctcaat
    18301 agagaaatca aaggcgatta tcataccttg gtagacgcga tcccgagcgc aaacaccata
    18361 gatcggcgtg cagaccgtga gaaaattaca gatattggaa tgattgactg caacaccttt
    18421 ggggcgacca gtagagcctg aagtatagat aatgtaacaa agttcgtcgg ctgtgtctgg
    18481 aattgcaata cgcgttgctg gctgaattgc aatcgcagca actacagtgt caagaactaa
    18541 caccttacag ctcgtacacg tgctgatact gctgaaagca gtgctggtta ctaacaaatc
    18601 tagggatgcg ttctcagcaa tgaagcctat tcggtcttgg ggaaaggatg gatcgagagg
    18661 tacaaaggca gcaccgcact taagtatcgc tagcagtgtt acataggtgt taattgaacg
    18721 ttccaataag atacctattc tgttaccaga accgagacct tggcgcaaaa agtagttagc
    18781 caatttattc gcctgtgtgt ccagttcggc atagctcaaa tgctctttat cgcagattag
    18841 agcgatcgca tcaggttgtg catcacatcg tctttcaaaa aagtagtgca aacgttgtgg
    18901 tggtatacct acctcatcaa attgaagatt gattgaattt actgtgctgg agtagtaatg
    18961 tgtctttgga tatctatgtg taattttcat ttaacaaaaa atttcttgag tttagaagcc
    19021 ttatttacta atgccgaatg cgagttaaaa ttctcctgaa aattatccag tgaattcttc
    19081 ataagcataa agtacctatg tttagtagtt tttcgtccta caaatacgtc gttttttaag
    19141 ataggaagta attgtaaaga acttagaaag attgctaaaa tggtgaaatg aaaaaataaa
    19201 cgttaaagtt taggggatcg ggaagaaaaa tttgcatact tgggtagaac ctaggaacgc
    19261 agtcggtgag gctctgtaga gcgcaccact ggaggcggag cctgggaacg aagtgacagc
    19321 caatcaaaat cagtgcggtg aaccactagt cacagtccca ccaactattg atgcagcttc
    19381 ctgactcgca taaagataga agtggggttt ttttaaaggg gtgggtcgtt cagcagatgc
    19441 tgtgtagaat taaccaatga attatgagag tcgcgctggt cttgaacagt tttaaaagtt
    19501 ttgataattg gcattaagca gcgtttggca tcttcataac cacgctgttt cagttcggta
    19561 atgcgatcgc taccatcaag cttatcaaat aattgaccaa tccaaccgcg atttttgcga
    19621 tagcggataa tatccttgct aacttgaata ccattgataa ggtcaattaa ggctttgtct
    19681 ccaactacag gaaatcgaag ttgcaagttt tgaagacaat gattagaagg gtgagtagac
    19741 gaaagttgta atcgatcgct caattcgtga aaagaagaaa tattgctcat aattctatat
    19801 cattaaacta tctgtaaatt ttagataggt atttatctta ctgatgttat catcagattc
    19861 tataataaaa ttccttagtt ctttaaccaa tttatctttt tattcagttt gttttttctg
    19921 gtctttctgc actgttacga agttgaacat cgttacttaa ttccgtaaga taactatgag
    19981 caatattgag tgcagatttg atacaacgag gcgctgcttt ctccatcaat gctgaaatcg
    20041 atctctttaa aaagagatcg aatcctgatt ttttccataa tctctctgct tttcgttgta
    20101 aatcttctgt agttgtttct tcaagttcct cttcccagtc catagcaaaa acttcctgag
    20161 ccaaagcatt gactgtcttc atatgggtaa tgagaacatc aggatttcgc tgtaattcca
    20221 ttaaaaagtt tgcagaggta aaagctcgtc gggcagaagt ttcaaacacg cgctcgcgct
    20281 cgctagcttc accaatacca aattcagcag cgacaaattg ctttacttgc tctgtactca
    20341 tatcaccttc acgtcgccga tcgactttat taatcaactc gtataaagtt tctacaccac
    20401 gtaatttaat aattttttga acttcttttt taactttctc tgaagcttct gttttcagtt
    20461 gggtaaaatc taaaactatc aaaactattg aacttcttaa gttccggcaa attctaataa
    20521 atcttcagca gaacttgtat actggacaaa aatatctagt ctgcgatttt gcaaattcaa
    20581 gcaatgaaaa gtttttcccc agaatcttgg gcttgagttg cagccttgaa agccagttaa
    20641 aatgccaagt cactgtcaat gtaaaagttt ggtttctacg cctaaattta tctcaaaatt
    20701 tagcaaaata ctataattag taaacaagca attttgaagc agaatatgac gacagtagcc
    20761 attttaccca tatatgatgc cagtggtcaa aagtcctacc gtgctgttgc aggtgataag
    20821 tactcgattg gtaaaactgc gggacaggca ttggatgctt taaccgctca attgggtgaa
    20881 aatgaattta gtgccttact actgcttcaa agttttcatc ctgaccagtt cttcggtatt
    20941 gagcaacaaa agcgtttatc cgaactcatg gatatgtgga gaactgcacg cgatgaagga
    21001 ctagagcttt cacaccaact acaacaagag ctagataatc ttgttgaggc agaactcaaa
    21061 gcagcaacag ccagaacagc ttcattacta caacagcaaa gccaatgaac ccaaagtata
    21121 cattagtttc taaacgagct ggtcatcgct gcgaatattg ccatgcccca gaacttgtct
    21181 tcaacttgcc ttttgaagtc gagcatatca taccactgag taagcaaggt actgattctg
    21241 aggaaaattt agcgcttgct tgtcgttcct gcaatctcca taaaagtaat cgtacaagcg
    21301 gagttgaccc tgactcaaat accgaagttc gtctctttca tcccaggcaa gaccaatggg
    21361 atgaccattt tcaagtggat gcaacatctg gaatgattgt gggaataact gcaattggga
    21421 gaactagtgt taatagttta gagatgaaca gccaaccaca ggttaccgca cgacaactgt
    21481 ggattcgttt aggtttgttt ccataagtct ctacaaatct caatacaagc tttgtaagct
    21541 ttctggcaac agttccctac tttttaactg caagaaaaca tttctcgata tgttgggttt
    21601 cgttcctcaa cccaacctac gaaaatttca cgcttaatga tgaaattctt tgacttttaa
    21661 ttttgtaatg cgaggtgttt ccccggcaat actacataaa atattcattg cctttaacaa
    21721 tcttcctctc ggtgcgcttc tacgctcgca aaattttatc ccaatctcta caagatcttt
    21781 tgtcactgaa aacagatctg gcgacatcgt caatggctga atatttttat ttccttcagg
    21841 caatgcaacc aatgtggtaa ttatctggta gagttcataa actgtcatgg cacgggcaat
    21901 aattggtagc agtggtatcc ctttatttcc attagtcatc cctttctggg caactttgcc
    21961 atccataata cgcaactgca gcaaaccagt gtcatttgca ttaccttccg tgacaaaacg
    22021 ggcatagact ccctcaccaa cctgactcca tggagtctct aaaacattcc ccgctcctgc
    22081 tgtcccatca ttaatcaaaa aaagatcggc tagattgcgc caattccctc cctttgctac
    22141 aagacgatcg cgtacctgtt tcatggcaaa taagctacgc cccgtgtccc caaggttcct
    22201 tgtaagaaac tcttgcaagg aatgcaagtg caatgcttga gaactttgat tccataactg
    22261 ttcgatctct tcccaccaac ccggttttaa agcagaacga tattgaggaa tcaatttatt
    22321 taccaaagct tgcatttcag caggcatatc tttatatgat gctccagctt gtaccgccca
    22381 agaaaggttt tgcaagtcct tttgagaaac atcggaactc gccgcagatc ggtttagtgc
    22441 ggcaagaact tccttgcggc taccgccata tctccccaat aaataacgat gtccgttagg
    22501 gctgcttgcg actctttgta aagaataaac ctttactgga atcacataat caccagcagg
    22561 caaaatttgc ttgggagaag caccttctaa atcaaggatg ttaggacgaa acgaaccacc
    22621 cggtagtgag gataccaaag gataaaggtt attgctattc gccgtaactg gggcattttg
    22681 ctcaacaagc actcgtattt gttttgctaa aaaagtctct gtgaaagaac ttttatcaat
    22741 acagaaactc cgaaggcata ttctcttttg accttgagca attcggtttt gttcctcaag
    22801 caagcttttt tctaaattag gtttatctgt aatagattga gaaccaatag ctttttgatg
    22861 aaaagttaaa atattgttaa atagtaacaa agatagcaag gaataggaaa aaaccttttt
    22921 tgtagaattc ataaacaaac agagatatca atttacgaat tattgacgcc ctattggtaa
    22981 tttgtcaatg ctgtgctaga tctgcaattg ttctgcttta tgataaaacc caacagcaaa
    23041 ttaagagcaa taccatcact taaaaatata aaataacgct acatcaggaa tcagcctcta
    23101 tcattgccaa taccgcccat cgctacaatc ttcccaggga gcgacaaaca ccaggcaaaa
    23161 gcgatcgcgc cccccgttgc tcctatagtg agaacgcgca gtgggtgcga tttttacatt
    23221 actgttattt taggacgatt tcggggaact atttacctat agtgccaccc tattattgtc
    23281 agttaactaa aatgtttctt ctacccggtc gaaatttcat tctctttttt gccacttgtt
    23341 tgtgcttgtt aggagtaagt tcgctccaaa taccacgcat gcaaaaattg cttcatacca
    23401 acaaaacagt gtcagtcaaa actttacaga gagaacttga tttagaaaga actcgtctaa
    23461 acttaattaa gaaaatacct agttttggct atgataatgt catagccaat tttgcctatc
    23521 tctggtttct ccaatatttt ggggacgatg aagttcgttc aaagacaggt tataatttaa
    23581 gcccggaata ctttgaaatc atattagcac gcgatcctcg atttataaat gcttatttgg
    23641 ggctttctac cagtacttct atgtatgccg ccatgccgga attttctatt aagttaatgg
    23701 agaaagggtt aaaatctcta tctccttttg ctcctacaaa gtcttattat gtttggcggt
    23761 ataaaggtat tgatgagttg ttgtttttag ggcaagcttt aaaagcacga caatcatttg
    23821 aaaagtcagc ggactgggca agttatcatt ccgatgaaga aagccaacac gctagagcaa
    23881 tctcaaagaa gactgcggag tttttagagc gcaatcccga tagtacatat gcgaggatag
    23941 caacttgggt gatggtatta aacaatcaag tggataaaaa aactcgtcag cgagctattc
    24001 ttgaaattaa agctttaggt ggtgacgtta ctgaaaatcc tgatggtact cacaaaatta
    24061 aacttcctaa aaaagattga aggaattatg aattatgaat tatgaattat gaattatgaa
    24121 ttatgaatac ataataaatt tataattcat gaaaatttac tggtataacg gtcagttaat
    24181 cgagtctcca actatagagt tagcaattga cgagccgggg ttactctatg gagcaacggt
    24241 ttttacaaca ttacgagttt acgatcgctc tcttgagagc aggttaactc actggcgggc
    24301 gcattgcgat cgcttaaagt cgagtctgga atcttttggt tggcaactgc caagtgaaga
    24361 aaggttgcgt caaggtgctt tatcgctcgc cgctcacttt cccgttttga gaattacggt
    24421 ctttcccgat gggagagaat ggataattgg tagagatctc ccagaaggat tgatagaaaa
    24481 gcaaagtcat ggtatactgg cagttcttgc aaaaccagaa ttttctcgct gtcttccgga
    24541 tcgcaaaaac gggaattatt taggtgcatg gttggcaaaa tctatcgctc aacagtcaaa
    24601 tgcacaagaa gcgatattag tggatgtcca aggcaattgg ttggaaacaa gtacgggaaa
    24661 tctctggggt tggttggatg gaagttggtg gacgccacct gcaacagggg agattttacc
    24721 gggaattatg agaggagaac tggtcaaatg gcttcgccaa gaggggctgg tggtgagaga
    24781 ggaaccttgg acgccgaacc tagtcaggaa gtttgaagcg cttgcctaca gcaacagtgt
    24841 agtggaaacc gtcccggtac ataccgttag ctcgccttta ggaaagctag aatataatcc
    24901 gcaccatcca tgttttcaac aactgcggat gttttttatt agcactatag gagtaaaatt
    24961 tggtataact taagataagt taatatattt cttaaaatct catctcttta cagagacgcg
    25021 atcgcacaag aagacaatta ggaggatttg cctcggtgaa taataaacga tggagaaatg
    25081 cggggctgta cgcgctgcta tttattgttg tcatagccct tgggacagca ttttttgaca
    25141 aacaaccaca aagcagagaa acatggcggt acagccaatt tattcaagaa gttcaaaatg
    25201 gtaatgtaga aaaagttagt ttgagcgcag atcggtctac agctcttgtc atgaccaaaa
    25261 atgacacgaa caagaagcta gtcaccttag tcaatgaccc tgacctgatc aatactctga
    25321 ctcaatacaa agtagatatc actgttttgc ctcaaaccga cgaaggattt tggtttaagg
    25381 cactcagtag cttatttttc cctgtattgc ttttggttgg tttatttttc ttgttgcgtc
    25441 gcgctcagaa tggacctggt agccaagcca tgaactttgg taagtccaga gccagagtgc
    25501 aaatggaacc acaaacccaa gtaacattta acgatgttgc tggtatcgac caagcaaagc
    25561 tagaactaaa cgaagttgta gactttttga aaaatgccga tcgcttcact gctgttggag
    25621 ccaaaattcc caaaggcgtg ttgctagttg gtcctcctgg aactggtaaa accttgctcg
    25681 cacgtgctgt agcaggcgag gctggtgtac cattcttctc catctctggt tctgagttcg
    25741 tcgaaatgtt cgtgggtgta ggtgcgtccc gagtccgcga cttatttgag caagcaaaag
    25801 ccaatgctcc ttgtatcgtc ttcatcgatg aaattgacgc cgtaggtcgt cagagaggtg
    25861 caggtttagg tggtggtaac gatgagcggg aacaaaccct caaccagtta ctaactgaga
    25921 tggacggatt tgaaggcaac actggtatca tcattattgc tgctaccaac cgtcccgatg
    25981 tattggatgc tgcattactg cgtcccggtc gttttgaccg tcaagtcgtc gtggatcgcc
    26041 cagactacgc cggacgagtt gaaattctca aagttcacgc ccgtggcaaa accctgtcaa
    26101 aagatgtgga cttggaaaga attgcccgtc gtaccccagg atttactggt gcagaccttt
    26161 ccaacctgtt gaatgaagct gcaatcctag cagcacgtcg aaatttaagt gaaatttcga
    26221 tggatgaaat taatgatgcc atcgatcgcg tattggctgg tccagagaag aaagatcgcg
    26281 tcatgagcga aaagcgcaaa acattagttg cgtatcatga agcaggtcac gccctcgttg
    26341 gtgctttgat gccagattac gatccagtgc agaagattag catcattcct cgcggacgtg
    26401 caggtggttt aacttggttc acccccagtg aagaccggat ggatactggt ttgtacagcc
    26461 gtgcttatct ggaaaatcag atggcagttg ctttgggtgg tcgcattgct gaagaattaa
    26521 tctttggtga agaagaagtg accactggtg cttctaacga cctgcaacaa gttgcacgtg
    26581 ttgcccgcca aatggtaaca cgctttggga tgagcgatcg tcttggacca gttgctctcg
    26641 gacgccagca aggcaatatg ttcctcggtc gggacatcat gtcagagcgc gacttttcag
    26701 aagaaactgc agctgctatt gatgaagaag ttcgccagtt agtagaaaca gcttaccgac
    26761 gcgctaaaga agttttggaa aacaaccgcc acattcttga caaacttgca gaaatgctag
    26821 ttgaaaaaga aactgtagac gcggaagagt tgcaagacgt acttgctagc aatgacgtta
    26881 aaactgcaac ttttgcatag ttataagtaa aaatttaaga tttaagattt aaataaatct
    26941 tagtttttac ttcttaatcg atgcgaatca gggtaatttt tgaattatcc tgattttttt
    27001 ataatttgtt atagcaatcc taaatcattt gtaaaaaatt tggattgcta atggctaata
    27061 gctaatggct aatagctaat ggctaatggc taatggctaa tagtgagacc agccctacag
    27121 gcggtgagtc cagtgctgca ggcaagccac tctcgtgcgg gggttccccc cgttgagaga
    27181 agtggcgcgg gtttcccgcg ccctggcgac tgtgagacca gtcctgtagg tgggtttccc
    27241 acgccctggg gactggcgta agccgttgcg ggcatagctt cgcaacgcgt agcgtctccg
    27301 ctcctgagat acccgaaggg gggttacccc gaatggcacg ctcgaagtgc gacgcggaga
    27361 ccaggggacg cggggacgcg gagagatgag gaagaaaaag tgatgagaga gcaatcctaa
    27421 aaatcaattg gttcaggaag tctgaaggca attggcactc ttagggatgc tcccaactgt
    27481 acccccgtgc aactcaatca aaatgactaa ttttctctgc caaaggtagg aagctaatat
    27541 ttgtataggc tgcaacactt aaacttagtc ttatgcatca tgttaaattt ccctcaagct
    27601 aaagtttggg ggatttattt tgctacaaga ttcgtgtgta gatagatgat tgatatcaag
    27661 ttcgggtaat tacaagtgtt caaccgaaca tgatatgact gtaaatacgc aatcggtgta
    27721 ttaatgctca tacaaaggct tcattcaatg ttctgttaca gaaactctct ttttcaaacc
    27781 catagaacgc agaatatccg cagctgacat ttctcccgtt ctacaaccac cttccatata
    27841 accttgaaac aattgggagc agtgttcgcc agcaaaaaat aaattcccca cccgttgttg
    27901 ttcaactcct gcaattgttg tccattgtcc cacaaggtaa caagcataag agcctctcgt
    27961 atacggttcc cgacgccaat aagcacaaac aggctgaccc cgatacatac taccaattcc
    28021 tggaaaaata ttttccaatt gggagagaag tttttgagct tgaatttccg gtgaatttag
    28081 ccctaatggt aaactctttt gaccgccagt aaaattggtg agtaaaccac ttgaaccctt
    28141 atgataatga gatgactccc agattgtttg aaagtttaag tcagtagaga caaatccagt
    28201 tgatttgtac cgcgtgcgcc aaatccgttc ttgataagca gtaattaatt tggcattgtt
    28261 accataacct aattctaaga tcgctttctt tttcaagtct ggcaaatcta catttaacga
    28321 gacattacgc aaagtactaa atggtagtgc caacaaaact cgctcataaa ttctttcaac
    28381 agagcggttt ccagagcgca aactcacccg atatctacca tcactttgag tagcgatcgc
    28441 ttctaattct gtctctagtt caatagaatt tttgaggaat tgtgataaag aaagaatgat
    28501 gcgatcgttt ccaccaacga tctgataccg ttcatcactt tcttcaattg gatcgaagct
    28561 gttagcatcc gtaccaataa ataacaacat atttaaacta gattgaattt cggtttcctg
    28621 accgtataaa cttgtgtaag ctttttcaat tatggcttta agaattggat gagttttggc
    28681 ttcctctaaa tattgagtga tagagatatt atctaattga atagccaatt gattctttgt
    28741 acggtaattt acaggcgttt tcccaaaagc tgccaaatct cgttctattt tttgtaccaa
    28801 tggcggtaac cactgttgta tttctttttc tgaaattaga cttccatcat aatacgatat
    28861 tccttctgtc aaattgctat ctatagcata caaatcaaca atctccagac ctaattcctt
    28921 tgccaaattg cgtaaacttg tgtgatgagt gtcaataaat tctcccccca aatctacagg
    28981 tatagaaaga tcggcaacat tatgcagcgt atgtatgcgt ccgccaacac gatttctagc
    29041 ttcaataata tctacaggga ctccagcttg agaaaggcgg taagccgcaa caagcccagc
    29101 aattcccgca cctacgacta aaactttagg aagtttggca aatgcagcag aacttcgttc
    29161 tccatcccac atcattgcac tcatagcact tgccaatccc aaaccgccat atatgagacg
    29221 gcggcgagtc atcttgtcgc ggacaatatc agctatttca tctgctcgaa tccctgtttt
    29281 tagcgatgcc ctggtgattt tataagctcg ccgcaatgat gccatcaacg ccgatcttga
    29341 cattgggtat gcctttatgt tttgcttttc aatcaagaaa tataccttaa aagcagcctt
    29401 aaacccgcag gaagttcaga ccacttctga gtgcttcatt ccatagaggc aatttctcaa
    29461 cttcttgcca agaaagcggt gggttcacga gttcggatcg ctcgtgttgt agagataatt
    29521 gccaccaacc aacatcatac cactgtccca gcttataacc aactgcccgg taaacaccta
    29581 ctaacgtaaa accgaatgct tcatgtagag caatacttgc gggattgggt aagacaattc
    29641 ctgcgaagac attgtaaaac ccttgaactt gaagcacttt aaatagagaa gcatacaaag
    29701 ctttacccac tgattttttc ctgtgcttcg cagcgacgta cactgatgat tctacagacc
    29761 attgatatgc tgcacgactt cgatgaggat tagcataagc gtaacctaaa atttctccat
    29821 caagttcaca gacaagccaa ggcagtcgct tttgataatc cttgatccgt tgtttaaatt
    29881 ctgcttcact tggaggttcc acttcaaaag aagttggcgt ttcacggaca ataggtgcat
    29941 atattgacag catttggaat gcatcatttt cattggctaa tcggattgta gctttcacaa
    30001 ttgatgagtt cttatctgat taatttctat aaagcttatc ttttaacgat ttttataaaa
    30061 cgatatatta tccctgaact taataaagaa atggcgctat tcttaactta gggtagcgcc
    30121 atttctttat taagagttgg caagtgcttt gagaaaaggg agtgcatttg tgcaagccgt
    30181 tacagttaca gctacagcta tttctaagca tcgcaaaaat caaaatttct gcgttgaaaa
    30241 tttatcttgc cgcttcaagc gattgtcgaa tatccttgaa gctcactttg cgttaaaact
    30301 gttccggttc gctaaagagc tgctgtagcg ctcgaacgac tttcggcggc gcgtcaagac
    30361 gttcgcagaa cgcttcccag cgatcgggcg gcaagcgaaa ctcggtttga ttcatgagaa
    30421 tagcatttgc ggcatcaagc gatgcttgca gcacaaactt gctgacattc gtgtgccgta
    30481 ttcgtgcggc ttctgccagt attgcctttt ccggctccgt tgcgcgaatg gaaagccgcg
    30541 tttcttttgg cgtagcggct gctacctcaa acatagtttt tctcctatag gtgtctttat
    30601 atgcccaatg tacaccccac tagtgaaggc tgcaatttat ttaaatttgg ttgtacccaa
    30661 aagccgattg ttccctttac cagggttcta acatcaagct tgctccagta aagttaggat
    30721 atcaatgagt ctcacttttg ctcccgcttg cataaataaa atagttatct gtgaccttaa
    30781 catctacttc aaagcccgct tgtattaact tgccacgaag ctgttcggga gaataaaaaa
    30841 ttttaacaat cttaaactct tggtcatcat ttaattttct attgatgtaa atattcccat
    30901 cgttttctaa tacatgattt ttggctgttg atgttgactc gaagcgagag tcaacaataa
    30961 aaatttgccc acctctgtgc gtcgctttat agactttttt taaaaatgag tcaaccaaat
    31021 ttggtggtac gtgagaaagc caaaaggaga aaaacactaa atcgtactca gtgttgggtt
    31081 cccaattaaa taaatcgatt tgctgatact cgacgttagc agcacctatt ttgctgcgag
    31141 caatcgcaat cacttcactt gaagcatcaa gtgcagtaat tttctgacca atctttaaaa
    31201 gttcttgagt ccaaattccc gtaccacagg ctaactctag aacgcgttct acattaccaa
    31261 tttggtacaa agcatttctg atgacaccag cttcgttaaa ccagcgctgg ttgagttctt
    31321 ctccgcgatc gtaacgtcca attctgtaga accattcgtc gtattcgtta gctcttgcac
    31381 tgtagtaggc aatttgttcc tgaagaatac tatctgtcat tatttcaaaa taaggagtgg
    31441 gtggtattta tgcaatacac aatgccaatg gctactatct taaaaatagg gaataggggt
    31501 taggtaagag aaattttatc gatgctctaa gcgaacattt ttcatcgaaa ctgcctaacc
    31561 tattgcgctt aaaagtctac aactaaccgt atcagtcgtt atcttaccgt aatttacaaa
    31621 caactttcgc cagcttaata taacttaaat tgatagatgt accgtattta aagttttagg
    31681 agttaattat ttagaacggc aatgcgtaat acaaactccc tggcttagat aaccaggagt
    31741 ttttcggtaa aagtgactag catcttacaa gcgatgtagt aaacttaagc catgagtatc
    31801 agtcccacaa ctgttaaaca ggctgtattc gctggctaac tgttgcactt gttctgactc
    31861 tctcgcactg ggtttccaag ggttgggatt gttgtaagcg taaaaagatt ctacgccatc
    31921 gatcccagca tctgcggcgg caggaatcaa atcaaagtgc gatcgccgat aacgcgctgg
    31981 gtgagccaaa acggctagtc cccctgcttc gtggatagca gatatcacat tagctgcttg
    32041 atggtgttcg cctgtcgtag cttttctttg aatgtaaggt ttgatgctgg gttgctctat
    32101 atcgaacgca taacctagaa tatgaacttc tgtattgaga agattggcgt taatttctac
    32161 accagtccaa agctggggta catttgcacc tggattattc catcgccatt gttctaacca
    32221 attttgcgct gcttgataac cagatatact atggtgatcg gtaatagcaa gcccttttaa
    32281 cccaatggta actgcctgct ccatcaatgc acttggttgg agcttaccat ctgagtggac
    32341 agtgtgcatg tgaaagttga aactcatcgg acagctcaat gcatttatgc tttgaaatat
    32401 atactttaat tgttcgcgtg aggtggaaac ctcggctacc ttgacagtca tacgtacctc
    32461 tttttcaaat aggtcatttt ttacacagaa aaacatgaca ctaatagccc agaatacacc
    32521 agcactacat ttgtgtgttg gttattagtt tccgggcatc tttggcaaat tttttcaata
    32581 tgttaagact acgttagcaa attcaaaggc tgacggtcat gcgtatattc gattggtttt
    32641 ataagaaaaa gtaagaaatt ttgcagatcc tatccgtcaa acttacaagc tacaactcca
    32701 gcaatcatcc actggtaaaa gaaaaaatgc aatgaaaaag aaaagaagct ttaaaaaaga
    32761 tgtataaaaa tatactattt aaattggcaa tcccaataat tcgccagaac cgggaataac
    32821 ctctccaatg gtacgagctg taatattttg taaagcaaaa tgtgtcatgg ctggctctac
    32881 ttgatgaggg ggaacaagca gtacaaaccc gatccccatg ttgaaagtgt tatacattgc
    32941 ttgtgcattc acagatccct cttcggctag ccactgaaat ataggtggaa tggaccaact
    33001 cttgggatcg atttttatcg cttgaccttt acccaagcaa cgaggcaaat tttcaggtag
    33061 ccctccacct gtaatatgtg ccatcccgtg gatttctaag cctgctttac gcgccgcgag
    33121 tacggattca acataaatgt aggtaggcgt gaggaaaatt tctcctagtg tttgccctcc
    33181 caatctatct ggacgatcgc tccaagaaaa tcctttgtcg ctgacaattt tcctgaccaa
    33241 gctaaagcca ttgctgtgta cgccagcact tgcaagagcg atcgcgacat cacctactcg
    33301 tacctgagaa ccgtccagca tctggctttt ctcaacaatt cccacacaga acccagccag
    33361 atcgtactca cccacctgat aaaaaccggg catttctgcg gtttctcccc caagtaagga
    33421 gcaccctgct tgcttgcatc cagaggctat acctgcaacc acctcagtta attgttcttt
    33481 ttccaaatga cttgttgcca ggtaatctaa aaaaaacaga ggttctgcac cagatgtcaa
    33541 cacatcattg acacacattg ctaccaaatc aatccctata gtgtcgtgac gattgacagc
    33601 ttgagcaatt ttgagctttg tacccacacc atcggttcct gaaaccagaa ccggttccct
    33661 ataacctgtt ggtagttgaa aacagccact aaaaccgccc aatccaccaa tcacttctgg
    33721 tctaaaagta ctgtgaacta aattccgaat ttgattgaca aattctcgcc cagcctcaac
    33781 atctacccct gcctctttgt agtccatccg tcagaacacc gataataaat tgtaagtggt
    33841 gagtggttag tgattagtac ctaataacaa ctatcaacta acaactaacc attaaaatac
    33901 ctcatcttca atgcccagcc accattcgcc caaattcatc aaatcttggc ggatatcttc
    33961 taactcttga acgtaatcaa cttctgtcat
//
