LOCUS       NZ_JHEG04000001        22778 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4143856
            Orig. end                         :: 4166634
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22778
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="20"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22778
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22778
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12778](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12778)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(357..371)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.29"
                     /tool="antismash"
     gene            616..1785
                     /locus_tag="HC643_RS16505"
                     /old_locus_tag="DA73_0400016485"
     CDS             616..1785
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016869263.1"
                     /locus_tag="HC643_RS16505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016485"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_038092578.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1e-32, bitscore:
                     111.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHILSVHNKYQIRGGEDESRESEEKLLQEMGHQVDVYEEDNQQIA
                     SLNPAQLGLKTIWSKEAYNIVKQKLRSAPYDIVHIQNFFPLISPSVYYAAKEEGVPVVQ
                     TLHNYRLLCPNALFFRNGGICEDCLGQLIPYPAVMHSCYRNSQIASGGVATMISLHRSM
                     NTWTKMVDAYIALTEFAKQKFIAGGLPEEKILVKPNFVSHDPGFSTESGGFALFVGRLS
                     VEKGLDTLLTAWEHLGTQIPLKIVGDGPLADQVVKAAKRLPQVEWLGRKPMSEVYTLMG
                     EAMFLVFPSKWYETFGRVAIEAFAKGTPVIAANIGAIAELVDSGRTGLHFCPGDAGDLA
                     AKVEWVLANPKKLAQMRQEARAEFEAKYTAEKNYQKLIEIYTKINKIVA"
     misc_feature    617..633
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.02"
                     /tool="antismash"
     gene            1810..3198
                     /locus_tag="HC643_RS16510"
                     /old_locus_tag="DA73_0400016490"
     CDS             1810..3198
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017309297.1"
                     /locus_tag="HC643_RS16510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016490"
                     /product="hypothetical protein"
                     /protein_id="WP_050045872.1"
                     /transl_table=11
                     /translation="MRSEIELYKKKDGYVRNSILLLLAFATAFFPRIIDAIGAPPTINF
                     VHFVIVPLACGIIISTTKVRNKKQKSIAKILLISLFVLLGVMIISALLNQAGVINVFLD
                     WMLLTEPFLVIIAMVSIPFSIERFKKFKTWIMGFISLHIFLAFAQHFLITFGILRVTSM
                     QPFDNVQGVFYLSGSGHVVGASVSMSFGLYFWLSTKGTPIWLRASVFTTAFIQLLFADA
                     KQVIVVWMIAWVLLVLTRLKDIKTALQYIIAAILVSYLLYWCIYNVEAFVAFKGWIRPE
                     LYGPEGKATILKSVPFQIIPSYYKSSLNWLFGLGPGHTIGRLGGWMLKDYSSLLEPLGA
                     TIHPASQAVWSFWFSPEYYWLDSSFFAPLWGWAGIWGDLGFLGLAAYLFICSIVWCRIC
                     QDDFSRFQLLTVMIYGFIFTQMEEPGYMLSTAMLIGLAWQERQIIRATRKSFLYPNGAI
                     NQSL"
     misc_feature    complement(3212..3225)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    3316..3325
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            3437..5401
                     /locus_tag="HC643_RS16515"
                     /old_locus_tag="DA73_0400016495"
     CDS             3437..5401
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024120.4"
                     /locus_tag="HC643_RS16515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016495"
                     /product="glycosyl hydrolase family 28-related protein"
                     /protein_id="WP_038092576.1"
                     /transl_table=11
                     /translation="MKHFSSVIFFIPLLGCVYGGISSIAQVQTSTSCTPNIKGIQGKYP
                     EKMNFVNVTAYPFCVKTNLNPENREAVRRNTIAIQKAIDEVANRQFAIKTLYFPKGVYY
                     FDNTLDFTNNGWQKLPRYLSVLGDSPKDSIIKLVDNAPGFKNPDRPKVFWKMANSNRAQ
                     NDAHNNYVRDLSIRTGANNLGVVAVDYVANNNGTIENVAIRSDDPQKRGAVGLGMLQRW
                     PGPSFVKDIEVEGFDYGIKLLSGQYGVFFEKVILKDQLKVGFYDNNYAVVRNFVSSNKN
                     PVPAFQSSKQPEQHSTIIDAVAVYTGKKATDTPAFDVGASQSFLRNATIKGYKYSLIKD
                     TTKLSGFIREYASKKSKLFSKSPDVSMNIPVPSSIQCDSCNDPKNWYIIESKGPTRNWV
                     GHDYTDEIQKAFASGKPVIQFAQIPGLPSKDTWPTNVIRFRKPLIVPSHVKRINFWYQG
                     NDKTTNFPAGKSLYVVSGKKTDTPLILDTPGGGGIHHIGSRTLLIKSSCIDYKSVPGAG
                     NVYFEDYCGSFTVAKGQKAYGWALNPERERYIHNKGGSLRIVGLKYEGNQTVIKTFDGG
                     KTELLGGYIYALGDWAKNRAIFESYDSEHSLIYLVVNHGHAGYDWSVKEVRGNTVKTRS
                     GVSDRNVLHVGYKAVPAPR"
     gene            complement(5434..6615)
                     /locus_tag="HC643_RS16520"
                     /old_locus_tag="DA73_0400016500"
     CDS             complement(5434..6615)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009456430.1"
                     /locus_tag="HC643_RS16520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016500"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_063779507.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.5e-66, bitscore:
                     223.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLSKNPENQNLRISTKPEIELILCCIRPEIDDVTTQKIQILVQ
                     KKIDWENLIHLAYTHGVIPLLYTRLNTICPKDISESTLQKFRSIFQSIATRNLFLTGEL
                     LKLLNFLKEQGIVAVPYKGPVLANLIYGNVALRQFVDLDILVQQQDIFAVKKLLISQGY
                     QPKLEMTYAEELDYLRAKTEHTYDFFHPQKGILIEVHWRIAPKYVSSIEPKHLWQDIEP
                     FSFAGTTISNLPLEDWIPILCVHGSRHMWIRLAWLCDLATLVQNHPNLNWEKVLELSQT
                     LGCRRILCLGLYLVNHLFGVALPKETWQKITEDNIVPTLLPKIYNELFGEVRTSERFLG
                     KSLYHLQVRERWQDKFLYIQSFLYWLIYRKGAKYLAFPLNHKVDNAKITHLTN"
     gene            complement(6612..8384)
                     /locus_tag="HC643_RS16525"
                     /old_locus_tag="DA73_0400016505"
     CDS             complement(6612..8384)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317176.1"
                     /locus_tag="HC643_RS16525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016505"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_237265892.1"
                     /transl_table=11
                     /translation="MLLVQGLLPAISMTLLRQLVDNLVVVVGGGVSWTSIQKILAPVGV
                     IGGLLLVGEFFSSAGEWIRTAQSELVHDYVTDLIHKQCVAVDYCFYESSEDNDKLNRAK
                     EGASGRALALLESTGSLLQNSITLFAVAAILLPYGLWLPMILVVSAFPAFYILMYLNKI
                     QYQWSQRTTTVRRWLIYYDSLLTGDQTAAEVRLFDFGDYFQSSYKKLHRQLTQEKLKLL
                     KKQTLGRFAAAIFVLLVSGVALAWMGRQVLLGILSLGDLALFVQAFNQGQGIVKSLLGN
                     LGQIYRNGLFISNLFEFLQIQPKIVNPPNPLPVPAIPKQGIHFRQVTFRYPGTEKPVLE
                     NFNLILPAGKIVVVVGDNGAGKSTLIKLLCRFYDPESGSIELDGIDIREFSVQELRRLI
                     TVLFQSPIPYYTTVSENIALGDIWAASNQTEIEAAAKASGIDDKIMQLPQGYNTMLGKL
                     FPEGTDLSGGQWQRLALARAFFRRAQIIILDEPTSAMDPWAEHDWLERFRTLASDRTAI
                     VITHRFTLAMRADIIHVMRAGQIVESGTHDELLAQDSLYAESWKSQMQAGTSNSFESSV
                     VGSLKQHKGNSTHL"
     gene            complement(8571..9473)
                     /locus_tag="HC643_RS16530"
                     /old_locus_tag="DA73_0400016510"
     CDS             complement(8571..9473)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015197637.1"
                     /locus_tag="HC643_RS16530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016510"
                     /product="hypothetical protein"
                     /protein_id="WP_038092574.1"
                     /transl_table=11
                     /translation="MKIYKAYNLCIASELPLAQLIETEDEPDIIVRFGKVDRATAREQE
                     GSKNVVGGIPEVGEFLIRDGQEIVMNPVPHVDETLLSTVILGPVLCVLLRQRGLLVLHA
                     SCIRMDKKAVAFMGGSGWGKSTLAAAFHSKGYDILTDDAMAIQFAAGNPIVIPAYPQFK
                     LFPEALTSLGHDTKGLHPVFQNASKLSYKFARGFYSSPLPLERIYVLAKGTSHEIVKLQ
                     PQEAFIELVRHTRAMKVMTDAEFMNSHMRLCGELIKNISFCRFTRKPGLTDLPQLVKLI
                     ENDLIPTSNCDQKTMARIF"
     gene            complement(9595..9801)
                     /locus_tag="HC643_RS16535"
                     /old_locus_tag="DA73_0400016515"
     CDS             complement(9595..9801)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016861769.1"
                     /locus_tag="HC643_RS16535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016515"
                     /product="lasso peptide"
                     /protein_id="WP_038092572.1"
                     /transl_table=11
                     /translation="MKSRYTAPKLTVYGNVAEITQILGSSSNNDFLFFNGNVNSSAAAS
                     PDAGSSDLCIGPAPSNANCGKLE"
     gene            complement(10001..12031)
                     /locus_tag="HC643_RS16540"
                     /old_locus_tag="DA73_0400016520"
     CDS             complement(10001..12031)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016872084.1"
                     /locus_tag="HC643_RS16540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016520"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_038092570.1"
                     /sec_met_domain="GATase_7 (E-value: 1.1e-30, bitscore:
                     104.9, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.2e-41, bitscore:
                     141.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGIVGIYYLDNRYVEHQELLSMTDTLVHRGPDGADIWVSGSVGL
                     GHRMLWTTPESIFEKLPLVNETGDLAITADARIDNREELISKLDFCDRPIEKITDSEFI
                     LAAYKKWGESCPEHLLGDFAFAIWDRHKKCLFCARDHFGVKPFYYYCQPRQGFLFASEI
                     KALLCLAEVPHCLDEVRIADFLTLMMEDKGITTYKDILRLPPAHSMVVNESELRLWSYW
                     SLDPNREIKLESDEDYAEEFKKIFTEAVRCRLRSAFPIISHLSGGLDSSAVTCVARNLL
                     TESEKYQLYTISTIFDKITECDERPYINAVLDQGGCIPHYVYGDQLSPLSNLDCIFQYE
                     DEALLGSSYFYPWNLNRTIKNLGMRICLDGFDGDTTVCHGMSRLTELAYQGKWKTFIQE
                     VTKVSQHFNFSPSAMFRGYGLPYLKNLAKQWRWIEFANAVQLIHKHFGSSRKQLILHHG
                     LKPLLPRVLQKFFQWRRKQKRSLASATSQTSLVNRDFAESIDLDKRIQQLVSSTNQPLS
                     VREEHWRNLTQGILAYTLEQMDRCAAMFSLEARHPFMDKRLVEFCLALPSEQKLYQGWS
                     RMIMRRGLAGILPEKVQWRGGKADLTPNFNDGFLNRDRQLLDEVMSHKIESMAKYIDLD
                     FLQAAYQRILSPGSQIADSDCIAVWQAVILALSLEFKGLVP"
     gene            complement(12028..12480)
                     /locus_tag="HC643_RS16545"
                     /old_locus_tag="DA73_0400016525"
     CDS             complement(12028..12480)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317180.1"
                     /locus_tag="HC643_RS16545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016525"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_050045875.1"
                     /sec_met_domain="PF13471 (E-value: 7.4e-22, bitscore: 76.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQLHSLFKLSGSDRSLLAITVILLGTIRMGLWLLEFRVLLKLLN
                     KIGQSNFLIFTSPSSSVSVSKIIWAVNVASRYMPYGVKCLARALTAWVLMSRYGYSSEL
                     RIGVAKDTAGRLEAHAWIEYEGRVAIGNLIDLSRFTPLPSLQGVKL"
     gene            complement(12464..12778)
                     /locus_tag="HC643_RS16550"
                     /old_locus_tag="DA73_0400016530"
     CDS             complement(12464..12778)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009456423.1"
                     /locus_tag="HC643_RS16550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016530"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_038092567.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.4e-25,
                     bitscore: 86.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.5e-17, bitscore: 60.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQKSLDGKVLESSVVVAVGEQISSDLGGEAVILNLKTGVYHGLN
                     QVGTQIWNLIQQPQHVEKIKQVLLQEYEVEAEVCMSDLLELLNNLKTTGLVEVRDETAT
                     "
     aSDomain        complement(12485..12718)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS16550_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.00E-27"
                     /identifier="RREFam002.1"
                     /label="HC643_RS16550"
                     /locus_tag="HC643_RS16550"
                     /protein_end="98"
                     /protein_start="20"
                     /score="86.0"
                     /tool="antismash"
                     /translation="EQISSDLGGEAVILNLKTGVYHGLNQVGTQIWNLIQQPQHVEKIK
                     QVLLQEYEVEAEVCMSDLLELLNNLKTTGLVEV"
     misc_feature    12822..12835
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.23"
                     /tool="antismash"
     misc_feature    13140..13155
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    13331..13344
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    13332..13345
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.38"
                     /tool="antismash"
     gene            complement(13502..13828)
                     /locus_tag="HC643_RS16555"
                     /old_locus_tag="DA73_0400016535"
     CDS             complement(13502..13828)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019489804.1"
                     /locus_tag="HC643_RS16555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016535"
                     /product="hypothetical protein"
                     /protein_id="WP_038092564.1"
                     /transl_table=11
                     /translation="MFFIRSGINFNIVCLLILNFLLNKLKRQKNKTYDYTQYICGCDYV
                     FEVAEGGTTGYMTGQGKGIKPGDYIILRDGSILCRYQVAEIDYYAEPPDMWMALLQKVT
                     VDSQ"
     misc_feature    13822..13835
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.85"
                     /tool="antismash"
     misc_feature    complement(13830..13844)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.18"
                     /tool="antismash"
     misc_feature    complement(13901..13915)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 24.91"
                     /tool="antismash"
     tRNA            14120..14191
                     /anticodon=(pos:4158008..4158010,aa:Gln,seq:ttg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="HC643_RS16560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="DA73_0400016540"
                     /product="tRNA-Gln"
     gene            14120..14191
                     /locus_tag="HC643_RS16560"
                     /old_locus_tag="DA73_0400016540"
     gene            14556..16742
                     /locus_tag="HC643_RS16565"
                     /old_locus_tag="DA73_0400016545"
     CDS             14556..16742
                     /GO_process="GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216: exopolysaccharide biosynthesis domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317184.1"
                     /locus_tag="HC643_RS16565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016545"
                     /product="tyrosine-protein kinase domain-containing
                     protein"
                     /protein_id="WP_038092561.1"
                     /transl_table=11
                     /translation="MLKSEQYQHPSSQAYATQSNEDEGGLNLGQVGASLRRRALLIAGV
                     TGVVATAAVLKAETDPPVYEGKFEILTKPVTGESRAVANVPQTLESQGKGIAPPEQAEP
                     VATTIQVLKSRGMLDPVVKRLQVKYQTKYPKLDYQKITKLLEIESQQQNILEVKFTSPD
                     EELVRDTLTLLKDAYIAYSLKERRGEVQQAINFVREQKTPLEAKVRAWQRKLQKIRQEH
                     NLVEPAQKAQEVSAQIATLTQQQAENRVQLEQMIASYQDLQRELAQQPGDRAGNSVLSE
                     NVRYQKILDQLQTVEIEVKKDAAKFTDTNPSLQFLQEQRANLLPMLTAEENRVKRDYQS
                     RIRALQARDRALGEKISYFNTYLRNLASVIRQYDDTQRDLKIVTDGLVQFTAKEQALKI
                     EQAQSLPSWKLLDPRLAEVTEPEAVKDSTKRNLALGTLLGLLLGTGAALVIDKLSNVFY
                     TSKDLKEATRLPLLGVVPLRKELGAMAWQEAASEEQQAARASFFEVFRSLYTNILLLSS
                     DAPIRSLVISSPGQEDGKTTVAIHLALAAAAMGHRVLLVDANLRNPTIHSRVGLMNIQG
                     LTDIIAQDLDWNNVIERSPLEDNLFVLSAGPTPPDSIRLLASRKMQDLMNDLQSTFDLV
                     IYDTSPLVGFADANLLAVNTNGLVLVAGLGKLKRTMFQQALEELQVSGTPILGVIANKS
                     KDATTTSYSYYQQYYKSMSAERVGHNEVLDSINS"
     gene            complement(16859..17338)
                     /locus_tag="HC643_RS16570"
                     /old_locus_tag="DA73_0400016550"
     CDS             complement(16859..17338)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015141433.1"
                     /locus_tag="HC643_RS16570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016550"
                     /product="hypothetical protein"
                     /protein_id="WP_038092557.1"
                     /transl_table=11
                     /translation="MVQYTLAQSPEIVLTVPGKDSTKAREKAMDQLMKLMDEGKLPTEL
                     EDGFGPQQLIELKEAPVETNSDEDAISQAVQVLSNLATLKLKVQESRTEALEIRKAVDV
                     LFLDKSVTEEEIARLKEGFKVLKNYAQANLRYHEARTKAEEARQILDRALKSPEK"
     misc_feature    17344..17357
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     gene            17895..20027
                     /locus_tag="HC643_RS16575"
                     /old_locus_tag="DA73_0400016555"
     CDS             17895..20027
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024840.4"
                     /locus_tag="HC643_RS16575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016555"
                     /product="DUF4114 domain-containing protein"
                     /protein_id="WP_050045876.1"
                     /transl_table=11
                     /translation="MAIISVTSAADSGAGSLREAVANAQPGDTIKFASNLANDKIILTS
                     GEIGILKPLTFDGSDASNLAISGNQQSRIFNIGNQENRINVTIKDLAFVDGRAVAGTTS
                     DQDFAAGGAIRIHDFSDVVVENSLFKNNVGERSGAIRVGFGGSLTVRNSTFDGNDGSIA
                     NDDHSAGAISTYGSGGIPDFDPGNGFVKIEGSTFTNNKGSEGGAVYSLLGPLTIEDSTF
                     KNNESTRDGGAVFTDGADKSEKDDLGGEITIRRSVFESNKAKGLGGGLSLWTYNPDKIL
                     IEDSSIVGNSVTYGGGAENNSKGGGLRVNSGYLTIRNTTIANNTSEHQGGGAWIDGTLT
                     VNIENSTFSGNSARDDMGGALTLNTPDNTPVNITNNTFVNNSAGRYSGAIWSNDRNSDD
                     ITLTNTIFAGNTASPQQMHTNYQLKDGGGNFVEKTVGDLGPKVTATATYVDDLKLSDTL
                     QLVGNRLMYVLESGSPAISGGTTNGATTKDQRGVLRDSQPDAGAFEFVPNGQIPVPSSA
                     SSNKGNNKTDDYQVMTPVDSFIDSQKLLIDLRSVDLDRDGKVDSKVSVTLDDIKSDAFY
                     NNSAGFYKIASADGAVLDSMTNKLIYPEDPGYAQAALKQRVSGGEINRNTGKLISQFDG
                     GALYAPYLIANGTVEQFLNNPFGNLQAFFSQGAANLDKTNHVKLLDNNQFGFEDLLNAQ
                     DPDFNDLTFKVKIQSS"
     gene            complement(20134..20265)
                     /locus_tag="HC643_RS42130"
     CDS             complement(20134..20265)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS42130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_272899747.1"
                     /transl_table=11
                     /translation="MKNKLTVSSIEFEFSLSADGVSSDVCSNEVPTPTGTQYGVGTL"
     gene            20281..21576
                     /locus_tag="HC643_RS16580"
                     /old_locus_tag="DA73_0400016560"
     CDS             20281..21576
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017314395.1"
                     /locus_tag="HC643_RS16580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400016560"
                     /product="hypothetical protein"
                     /protein_id="WP_038092554.1"
                     /transl_table=11
                     /translation="MAPNPTIMRTVEQLGYRVTVGDVATQAGLNVAEANQGLLALASDA
                     GGHLQVSETGDIVYLFPKNFRDILRNKYFQLRLQEWWQKIWGIIFYLIRISFGIFLIAS
                     IALITLSIILIISAANSDRDGDDRGSSFSFFYFPDIFWYLSPDYDTHQRQRRREKSHLN
                     FFEAVFSFLFGDGNPNANLEERRWQEIASVIRKNRGAIVAEQIAPYLDDIGEGSAKEYE
                     DYMLPVLTRFNGQPAVSPEGEIVYYFPELQVSAVLQGGIPSQGSAKSVRRSDAQQHYDP
                     LSDHLMEFSWRFSAATSGQIMLSAGLGVANFVGALVLGSLLRDGVVAAQLGGLVAFVQG
                     IYWLLLAYGTGFLAIPLIRYFWIQWRNSKISSRNRVRQERARLLADPNTQLEQKISYAR
                     QFATAKVIGTDDLAYSTETDLLEQEFKKNDEL"
     misc_feature    21757..21775
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 25.8"
                     /tool="antismash"
     misc_feature    complement(22563..22582)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 21.22"
                     /tool="antismash"
ORIGIN
        1 gcatcgttta gacaacaaca ccgtgtttca ccagaaactt tatgtatact caatgtgggt
       61 tcaaatcatc cacgcaagaa tatttttaca gcattgaaag tcattaaagc gcttaaagat
      121 aaaggattat ctattcagtt ttggaaagca ggtgcagatt ttactgccga gcaaaaaaaa
      181 tttattcaaa cacacagctt agaaaactgc gtcacctatt taggtaagcc agacaaagag
      241 agcttagtta atatttataa cgcagctgat gtgcttttat ctccctcact ttatgagggt
      301 tttggaataa caattttaga ggcaatggcg tgtgggacag ttgtcatcac ttctaatgta
      361 acatcacttc cagaagtcgc gggtgatgct gctattttag tagcaccaaa cgatgttaca
      421 acgatggtga aggctgtagg cgagctttta gaaaaacctt tatatcgaaa atcattagtc
      481 gaacgcggtt tagcaagggt caaaatgttt acatgggaga aaacagcgga gcaagttgcc
      541 actctttatg aaaaacttct ggaaaaagaa aggaaaaatt agttatctat gaattaattc
      601 aagaggattt ttaaaatgca cattttaagt gtacataaca agtatcaaat ccgtggggga
      661 gaagatgaat ctcgcgaatc tgaagaaaag ctcctgcaag agatgggtca ccaagtagat
      721 gtgtatgaag aagataatca gcaaattgca tctctaaatc cagcacaatt agggttgaaa
      781 acaatttggt caaaagaagc ttacaatata gtcaaacaaa aacttcgtag cgcaccctac
      841 gatattgtcc acatccaaaa tttttttcct ttaatttctc cctcagtata ttatgctgcc
      901 aaggaagagg gagtacctgt agttcaaact ttacataact atcgactgct atgcccgaac
      961 gctctatttt tccgaaacgg aggcatttgt gaagactgtt tgggtcagtt aatcccttat
     1021 cccgcagtga tgcatagttg ttatcgcaac agtcaaattg ctagtggcgg agtagcaaca
     1081 atgattagcc tgcatcgaag tatgaatacc tggacaaaaa tggtagatgc atatattgct
     1141 cttacagagt ttgcaaaaca aaaatttatt gcaggtggtc ttcctgaaga aaagatatta
     1201 gttaaaccaa actttgtgag tcacgatcct ggttttagta cagagtctgg tggctttgcg
     1261 ctttttgtag ggagactttc tgtagaaaag ggtttagata ctttattaac tgcttgggag
     1321 caccttggta cacaaatccc tctcaaaatt gtcggtgatg gtcccctagc tgaccaagtc
     1381 gtaaaagcag caaaacgact tcctcaagtt gaatggctag gacgcaaacc aatgtcagaa
     1441 gtttatacct taatgggtga agcaatgttt ttagtgtttc cgtcgaaatg gtatgaaacc
     1501 tttggtcgcg tagcaattga ggcttttgcc aaaggaactc cagtcatagc tgctaatatt
     1561 ggtgctattg cagaacttgt agattctggt cgtaccgggc tgcatttctg tcctggggat
     1621 gcaggggatt tagcagcaaa ggtagagtgg gttttagcga atccaaaaaa gctagctcag
     1681 atgcgtcagg aagcgcgggc tgagtttgaa gccaagtata ctgctgagaa aaactaccaa
     1741 aagcttattg aaatttatac taaaattaat aagattgtag cttgattaat tgcagaaaaa
     1801 gggtaataaa tgagatcgga aatagagctt tataaaaaaa aagacggata tgttagaaac
     1861 tccattctat tactattagc atttgctact gctttctttc ctcgaattat agacgctata
     1921 ggcgcacctc caactattaa ttttgttcac tttgtaattg ttcctcttgc ttgtggaatt
     1981 ataattagta caactaaagt taggaataaa aagcagaaat ctattgcgaa aattctctta
     2041 ataagcttat tcgtcctact aggtgtcatg attattagtg ctcttctaaa tcaagctgga
     2101 gttattaatg ttttcttaga ttggatgttg cttactgagc cttttctagt aattatagca
     2161 atggtttcta tccccttttc tattgaaagg ttcaaaaagt ttaaaacttg gattatgggc
     2221 tttattagcc tacatatttt tttggctttt gcccagcact ttctaattac ctttggcatt
     2281 cttcgagtaa ctagtatgca gccctttgac aatgtccaag gagttttcta cctttctggc
     2341 tctggccatg ttgttggtgc ttctgtttct atgtcttttg gtttgtactt ttggctcagt
     2401 acaaaaggaa ccccaatctg gttgcgagct tctgtgttta ctacagcctt cattcaactt
     2461 ttatttgctg atgcaaagca ggtaatcgta gtctggatga tagcctgggt actactggta
     2521 ctaactagat taaaagacat aaaaactgct ctacaatata taatagctgc tatattggtt
     2581 agttatttgc tatattggtg tatatacaac gtggaagcct ttgttgcttt taaaggctgg
     2641 attagaccag aactttacgg tcctgaaggt aaagctacaa tacttaagag tgtacctttt
     2701 caaataattc cttcgtatta taaatcatcc ttaaattggc tatttggttt gggtcccggt
     2761 cacactattg gacggttggg ggggtggatg ttaaaagact atagtagttt attagagcca
     2821 ttaggtgcta ctattcatcc tgctagtcaa gctgtttggt ctttctggtt cagtccagag
     2881 tattattggc tggactcaag ttttttcgct cctttatggg gctgggcagg aatttgggga
     2941 gatttaggat ttttgggtct ggcagcttat ttgtttatct gttcaatcgt ctggtgtcgg
     3001 atttgccagg atgacttttc caggtttcag ttacttactg taatgattta tggttttatt
     3061 tttactcaga tggaagaacc tggatatatg ctctctacag caatgctcat tggtttggca
     3121 tggcaagaac gtcaaattat cagagctacc cggaagagct ttctataccc caatggagct
     3181 attaatcaat cgctctaact aacgatagta ttttttttaa ataattttat aatgtttatt
     3241 aaagatcgta aattttagag aattttaaga tattatccca acattatacg taattttaat
     3301 ctggatttta atgcttgttt tttgaaagtc attaagtaat agattggtcg gttatgaacc
     3361 gttgaggtat tctataaact cttgtaacgt caattatatt ttataagtaa ttttgacgga
     3421 actattgtgg gtaaaaatga aacatttttc atcagtcata ttttttatac cactgctagg
     3481 ctgcgtttac ggaggcattt cctccatagc gcaggttcaa accagtacat catgtacgcc
     3541 gaacatcaaa ggtattcagg gcaaataccc tgaaaaaatg aattttgtca acgttacagc
     3601 ctaccctttc tgcgtcaaaa caaaccttaa tcccgaaaac cgagaggctg taaggcggaa
     3661 taccattgct attcaaaaag caattgatga agttgctaat cggcaatttg ctatcaaaac
     3721 attgtatttt cctaaaggtg tttattattt cgataatacc cttgatttta caaataacgg
     3781 ttggcaaaag cttccccgtt atttatccgt attgggcgat agtccaaagg attcgattat
     3841 taagcttgtt gataacgcgc caggtttcaa aaatcccgat cgacctaagg tcttctggaa
     3901 aatggcaaat tccaaccggg cgcagaacga cgcgcacaac aattatgtac gcgaccttag
     3961 tatcaggaca ggagccaata atcttggggt agtagcagtt gattacgttg ctaacaacaa
     4021 tggtactatc gagaacgttg caatccgctc cgacgatcct caaaaacgtg gtgcggttgg
     4081 gctgggtatg ttgcaaaggt ggcctggtcc ttcgttcgtc aaagatattg aggttgaagg
     4141 ctttgactac ggcatcaaac ttttaagcgg tcaatacggc gttttctttg agaaagttat
     4201 cctcaaggat caattgaaag tcggctttta tgataacaat tacgctgtag tgcgtaattt
     4261 tgtgagtagc aataaaaatc cggtaccggc attccaatct agtaaacaac cagagcagca
     4321 ttcgacaata attgatgccg ttgctgtata taccgggaaa aaagcaactg atacgcctgc
     4381 attcgatgta ggagcttccc aaagcttctt acgtaacgcg actatcaaag gatataaata
     4441 ctctttgata aaggatacaa cgaaattaag tggttttatt cgcgagtacg catcgaaaaa
     4501 gtccaagcta ttctccaaaa gcccagacgt gtcaatgaat attcccgtcc catcctctat
     4561 tcagtgcgat agctgcaacg acccaaaaaa ctggtatatc attgaatcaa aaggtccaac
     4621 tcgtaactgg gtcggacatg attacactga cgaaattcaa aaggcatttg catctggcaa
     4681 gccagtcatt caatttgcac agattccggg tcttccatcc aaagatacat ggcccactaa
     4741 tgttattcgc ttccgtaaac cactcatcgt tccttcccac gttaagcgga tcaatttctg
     4801 gtatcaaggc aacgataaaa ctacgaattt tcccgcaggc aaatcgcttt acgttgtaag
     4861 tggcaaaaaa actgatactc cactcatcct ggatacccca ggcggtggcg gaatccatca
     4921 cattggatcg cgtaccctgc tgattaaatc ctcgtgtatt gactataaat ctgttccagg
     4981 agcaggcaat gtctattttg aagattactg tggctccttt acagtagcca aaggacaaaa
     5041 agcctatggt tgggctctta atccagaaag agagcggtat attcacaaca agggtggctc
     5101 gttacgtatt gttggattaa aatacgaggg caatcagact gttattaaaa cattcgatgg
     5161 tggtaaaact gaattgctag gcggctacat ttatgcctta ggggattggg ccaaaaatcg
     5221 agctatcttt gaaagctatg attccgaaca ttctcttatc tatctcgtcg tcaaccacgg
     5281 tcatgccggt tacgattggt cagtaaagga agtgcgtggc aacacggtga agacccgcag
     5341 tggtgtctcg gatcgtaacg tgcttcatgt cggttacaaa gcagtccccg ctccgaggta
     5401 gtgtcgaata ctgttaacga attacacaaa acctcaattt gtcaggtggg taatcttggc
     5461 attgtccact ttatggttaa gaggaaatgc taagtattta gcaccttttc tataaattaa
     5521 ccaatataag aaagattgga tatacaagaa tttatcttgc caacgttctc ttacttgaag
     5581 atggtaaagg cttttgccaa gaaacctttc tgaagttcta acttcaccaa aaagctcgtt
     5641 atagatttta ggtaacaaag taggtactat attatcttct gttatctttt gccatgtttc
     5701 ttttggtaaa gcaactccaa aaagatgatt caccaagtat agccctaaac aaagtatccg
     5761 cctacagcct aaagtttggc tcaattcgag gactttttcc caatttaggt tcgggtgatt
     5821 ttgaacaagc gtagcaagat cgcacagcca tgctagtcgt atccacatat gcctagatcc
     5881 atgtacgcag agaattggta tccaatcttc taaaggtaag ttggatatag ttgtgcctgc
     5941 aaaggaaaac ggttctatat cttgccacaa gtgtttgggt tcaatggaag acacatactt
     6001 tggagcaatt cgccaatgca cttctataag aattcctttt tgagggtgaa aaaagtcata
     6061 ggtatgctca gttttagctc tcaagtagtc aagttcttct gcataagtca tttcaagttt
     6121 gggttgatat ccctgagaaa tcagcagttt tttaacagca aagatatctt gttgctgaac
     6181 taagatatcc aagtctacga actgacgcaa agctacatta ccgtatatta agtttgctaa
     6241 aactggtcct ttgtatggta cggcgacaat tccttgctct ttcaagaaat ttaggagctt
     6301 aagaagttct ccagtaagaa ataagttacg cgtagcaata gattgaaaga tgctgcggaa
     6361 cttttgtaag gtagattcag agatatcttt tggacaaatc gtattaaggc gagtgtatag
     6421 caaaggtatt acaccatgtg tatatgctaa gtgaattaaa ttctcccaat ctatcttttt
     6481 ttgaaccaat atttgaattt tttgcgtagt tacatcatca atttctggac ggatacaaca
     6541 aagtattagc tctatttcgg gtttagtact aattcgtaaa ttttgatttt ctgggttttt
     6601 agataaagtt gtcataaatg agttgaatta cctttgtgtt gttttaaact tccaaccaca
     6661 ctactttcaa atgaattgct tgtaccagct tgcatttgtg atttccaaga ttcagcgtag
     6721 agactgtctt gagccaagag ttcatcgtga gtacctgact ccacaatctg accggcacgc
     6781 ataacatgaa taatgtctgc ccgcatagcc aaagtgaaac ggtgagtaat gacaatagca
     6841 gtgcgatcgc ttgccaaggt gcgaaatcgt tctagccagt cgtgttcagc ccaagggtcc
     6901 atagcgcttg taggttcatc caaaataatg atttgagcgc gtctaaaaaa tgcccgtgcc
     6961 agagccagac gctgccattg gccaccgctt aaatcggttc cttctggaaa caacttaccc
     7021 aacatcgtgt tatacccttg gggcagttgc ataatcttat cgtcaatacc cgaggcttta
     7081 gcagcagctt caatctctgt ctgattcgat gctgcccata tatcacccaa agcaatattt
     7141 tcactaactg ttgtgtagta gggaattgga gactgaaaca aaacagtaat taacctacgg
     7201 agttcttgta cggaaaactc acgtatatct atgccatcta attcaatgct tcctgattca
     7261 gggtcataaa agcgacataa aagcttaatc agcgtacttt ttcctgcacc attatcacca
     7321 acaactacca caattttgcc agcaggcaat attaggttaa agttctctaa cactggtttt
     7381 tctgtaccgg gatagcggaa cgtaacttgc cgaaagtgaa ttccctgttt gggtattgct
     7441 ggtacgggca aaggattagg cggatttaca attttgggtt ggatctgcaa gaactcaaac
     7501 aagttactga taaataaacc attacgataa atctgcccta agttacctaa caaagatttg
     7561 acaataccct gtccttgatt aaacgcctga acaaagaggg ctaaatcccc taaactcaga
     7621 attcctagca atacttgcct tcccatccaa gctaaagcaa caccagaaac gagcagcaca
     7681 aagatggcag cagcaaatcg acctaaagtt tgctttttca gtagcttaag tttttcttgt
     7741 gtgagttgtc gatgcaactt tttgtaagac gactgaaaat aatcaccaaa gtcaaacagc
     7801 cgtacttccg ccgccgtttg gtcaccggtc aaaagcgagt cataataaat taaccagcga
     7861 cgaacagttg ttgttcgttg cgaccattga tactgaattt tatttagata cattaatata
     7921 tagaatgcag ggaaagcact aactactaga atcatcggca gccaaagacc atagggtaac
     7981 aagattgctg ccacagcaaa cagagtaatg ctattttgca ataaactacc cgtactttct
     8041 agtaatgcga gagctcgccc acttgctcct tccttagctc ggttaagctt atcgttatcc
     8101 tctgaggatt cataaaagca gtaatcaaca gcaacgcact gtttatgaat caaatcagtg
     8161 acataatcgt gtactagttc tgattgagca gtacgaatcc attcacccgc actactaaaa
     8221 aactcgccta cgagtaacaa acctccaatt acccctacgg gagccaaaat cttctggatg
     8281 ctcgtccaag aaacaccgcc tccaacaact accaccaaat tatctactag ttgtcgaagc
     8341 agagtcatgg agatagcggg aagcaatcct tgaactagca gcataattat ccaagctaca
     8401 gtccagtatc gcgatgcggc ccaaaccaag ctaaaaattt tatgtatttg aaatagaatt
     8461 ttattcgcgc tactaaattg tcttaacaac gtaacagcac ctcttaatat tagggataaa
     8521 gaatagagtt tgaagccact tgacagctaa cagtaaacga taaaaggcag ctagaaaatt
     8581 ctcgccatcg ttttttggtc acaatttgat gttggtatca agtcattctc aatcaacttt
     8641 acaagttgtg gtaaatcagt taagccgggt ttgcgagtga aacgacagaa actaatattt
     8701 ttaataagct cgccacacaa acgcatatga gaattcataa attctgcatc tgtcatgact
     8761 ttcatggcgc gagtatgacg tactaactca ataaaagctt cctgaggttg tagcttgacg
     8821 atttcgtgag atgttccttt agcaagtaca taaattcgct caagcggtaa gggagatgag
     8881 tagaaaccac gagcaaactt ataagataat ttggatgcat tttggaaaac cggatgcaac
     8941 cccttagtat cgtgtcctaa agaagtaagt gcctcgggaa aaagtttgaa ctgaggataa
     9001 gcaggaataa caatcgggtt gcctgccgca aattgaatag ccatggcatc atctgttaat
     9061 atgtcgtacc ctttactatg aaatgctgct gctaaagttg acttacccca cccggaacca
     9121 cccataaacg ccactgcttt tttgtccata cgaatacaac ttgcatgtag aactagtagt
     9181 cccctttgac gcagcagtac gcataataca ggacctaaaa ttacagtgct tagaagagtt
     9241 tcgtccacat gcggtacggg attcataaca atttcctgtc cgtcacgaat caaaaactca
     9301 cctacttctg gtattcctcc cacaacattt ttgctacctt cttgttccct tgcagttgca
     9361 cgatctactt taccaaatcg tacaattata tcaggctcat cctcagtttc aattaattga
     9421 gcaagtggca attctgacgc aatgcataag ttgtatgctt tgtagatttt cataataaat
     9481 ccgaggttag ataagtattg cctaccaaaa gtttcgtaag gtgggcaatg cccaccctac
     9541 tttatctttc aaaagtccaa taggattcct acatttgcgc ctttgcgtct aactttattc
     9601 caactttccg caattagcgt tagatggagc aggtcctata caaagatcgc ttgaacccgc
     9661 gtcgggggaa gccgcagcac tggagttaac attgccgttg aagaacaaaa agtcattgtt
     9721 tgatgagctg ccaagaattt gggtaatctc agcaacatta ccgtaaacag tcagcttggg
     9781 agctgtgtat ctacttttca tgaatctatc tcctgatttt gagtatatag ttaacggagt
     9841 tatttgttgc agatagcacc aacctggact tacagcgtag ctttttgatt aaaaccacaa
     9901 cctgccaagc tctcagtctg tggtgatgca ccagcttaac tggacttacg gcgatcgcac
     9961 tgttatctat acagattcac cacctgccaa gtttacgtaa ttagggtact aatcctttaa
    10021 attccagcga taatgccaaa atcactgctt gccaaactgc tatacaatca ctgtcagcga
    10081 tttgactccc tggtgataag attcgttgat aagctgcttg caaaaaatcc aaatcaatat
    10141 attttgccat gctttctatt ttgtgagaca tgacctcatc tagaagttga cgatcgcggt
    10201 ttaaaaaccc gtcattgaaa ttgggtgtca gatccgcttt tcccccacgc cattgaactt
    10261 tctctggcaa aatacctgcc aaaccacggc gcataatcat ccggctccaa ccttggtaca
    10321 acttttgctc ggaaggtagt gccagacaga attcaaccag tcttttatcc ataaatggat
    10381 gacgagcttc caaggaaaac attgccgcac accgatccat ctgctctagg gtgtatgcta
    10441 atataccctg agttagatta cgccaatgct cttctcttac acttaggggt tggttggtgg
    10501 aactaactaa ctgctggata cgtttatcca aatcaatact ttctgcaaag tcacgattga
    10561 ctagagaagt ttgggaagtt gctgaagcta gtgacctctt ctgctttctc cgccactgga
    10621 aaaacttctg tagtactctt ggaagtagag gtttaagccc gtgatgcaaa attaactgtt
    10681 tgcgcgaact accaaaatgc ttgtgaatta actgcacggc attggcaaat tctatccaac
    10741 gccactgttt tgctaaattc ttgaggtaag gcagaccgta accccgaaac atagcactag
    10801 gagagaaatt aaagtgttgc gaaacttttg ttacttcctg tataaaggtt ttccactttc
    10861 cttgatatgc aagttctgta agcctgctca taccgtgaca aactgtcgtg tcaccgtcaa
    10921 aaccatcaag gcaaattcgc atccctaaat tcttgatagt gcggttcaag ttccaaggat
    10981 aaaaataact ggaaccaagc agggcttcat cttcgtactg aaaaatgcaa tcgaggttag
    11041 atagcggact cagctggtct ccataaacat aatgaggaat gcatcctcct tggtctaata
    11101 ctgcattaat atacggacgt tcgtcacact cggtaatctt atcaaaaata gttgagattg
    11161 tatataattg atatttttct gattcagtta ataagtttcg agctacacaa gttacagcag
    11221 aagaatctaa tccaccactc aagtggctga ttatgggaaa agcgctacgc agacggcaac
    11281 gcactgcttc tgtaaaaatt tttttaaatt cctcggcgta atcttcatca gactctaact
    11341 taatttcacg gttagggtcg agagaccagt aagaccacag gcgtagttct gattcattga
    11401 caaccatact gtgcgctggt ggaagccgta ggatgtcttt gtaggttgtg atgcctttgt
    11461 cttccatcat caaggtcaaa aagtcagcaa ttctaacttc atcaaggcaa tgaggtactt
    11521 ctgctaaaca cagcaatgcc ttgatctcag aggcaaataa aaagccttga cgcggttgac
    11581 aatagtaata aaaaggcttg actccaaaat gatctcgcgc acagaataaa catttcttgt
    11641 gcctatccca aatcgcaaag gcaaagtctc ccaaaagatg ctccggacaa gattcacccc
    11701 acttcttata agcagcaagg ataaattcac tatctgtaat tttttctatt gggcgatcgc
    11761 agaaatctag cttagagatc aactcctctc gattatcaat acgagcatct gcggtaatag
    11821 ctaaatcgcc tgtttcatta acgagtggta gtttctcgaa tatagattct ggcgtcgtcc
    11881 acagcattcg gtgtcccaaa cctacagacc cgctaaccca aatgtctgca ccatcgggtc
    11941 cccggtgtac caaggtatca gtcattgaca gtagctcttg atgctctaca taacgattat
    12001 caaggtaata tatccctaca ataccgctca taatttgact ccttgtaaag atggcagtgg
    12061 agtaaatcga gagaggtcta tcaaattacc aatcgcaact cgtccttcat actcaatcca
    12121 agcatgagcc tctaaccttc ctgctgtgtc tttggcaaca cctatccgta gttcggacga
    12181 atacccgtaa cggctcatta gcacccaagc agtcaaagca cgcgccaaac actttacccc
    12241 atatggcata taacggctag ctacgtttac agcccaaata attttgctca cagaaacaga
    12301 actgctagga gaagtaaaaa tcaggaaatt cgattgaccg atcttgttca gaagtttaag
    12361 taatacgcga aactccaaca gccataaccc catcctgata gttcccaaca gaatcacagt
    12421 tattgctaac agagagcgat cgctccctga aagtttgaac aagctatgta gctgtctcat
    12481 cccttacctc aactagccct gtagttttta aattatttag cagttctaat aagtcactca
    12541 tgcaaacttc tgcttcaact tcgtactctt gtagaagcac ttgtttaatc ttctctacat
    12601 gctgaggttg ctgaattaaa ttccaaattt gtgtaccaac ctgattcaat ccgtgataaa
    12661 cccctgtctt gagattcaaa attactgctt ctccacccag atctgaagaa atttgctctc
    12721 caacagctac cactacagat gactctaaca ctttcccatc tagtgatttt tgtgccataa
    12781 gcttgagatt ttcccttttt gattcaatac tttttttcaa aatttttaca aaaaactctg
    12841 ttgctataaa tttttagcca aaaattattt agtaacagat gattctcgaa ccttcccatc
    12901 tttcattgca aaggtttttt catccagata tagcaatcct atttgaaatc taaaccaggg
    12961 agacaaggag gacaaggaag acaaggaaga ggtgtttgta aatcatttat gattgctata
    13021 gactattatt aattctgttg cacgaccaac ctaacaattt tattggcagt gattcttgca
    13081 gcataatagc ctgacaacga aactttattg aaaaaaatta cgttgtaaca atttttacat
    13141 tcacatcttt ttgaagcagc gtttccccga taccatagtt ttcaaagatt caaggcttta
    13201 ctacatttca ctgtgtatag tggtagattc tcaacccaaa cacaaaaccc tatattccca
    13261 atttggagat gcttttcaat ttcgttctca ttctagtata cgctcaatga ggtttctaaa
    13321 acgataagta aatttataaa aaaaacatat taattttaag aaattgtaaa tgaatatttg
    13381 ataatcctag tgaaatctat ttttttgtca agaaaggttt caattctctt ttaaaatatg
    13441 ttcctcaatt gatattgctt aattaaccaa acttggatag aaacattctt gtaactgagt
    13501 tttactgtga atcaaccgtc accttttgga gtaaagccat ccacatatct ggtggctcgg
    13561 cataataatc aatttctgca acctgatatc gacataaaat agaaccatcc cgcaaaatta
    13621 tgtaatctcc tggtttgata cctttacctt gtcccgtcat ataacctgtc gttccaccct
    13681 ctgctacctc aaatacataa tcgcaaccgc aaatatactg agtgtaatca taagttttgt
    13741 tcttctggcg ttttaattta ttcagtagaa agttcagtat taacaaacaa acgatattga
    13801 agttgatgcc tgacctgata aaaaacataa gttttttgaa aatttacaga gaattggcat
    13861 gagagatgcc ctgatgaggg ctagaaatca aaacctaaaa tgaaaatgaa taccaagtaa
    13921 aagctaaacc tatagattgt tattttaagt tatgtcagcc ttagatggcg aatgtaagct
    13981 aaaaaagcta ctacctaaag gtagaagtta agaaagcatc gggtcgaaga acatgacaaa
    14041 tccggttgcc taaaattaat tgtcaaagta cttgacactt cccctggagt tactgctata
    14101 ttaattaacg tgaatgtgat ggggcgtagc caagtggtaa ggcagcgggt tttggtcccg
    14161 ccatccctag gttcgaatcc tagcgcccca gtatttaaca gggtagacat gaaagagtct
    14221 accctgtaat tttatgcgat aatcctcgca attgttactg agttgacagg taactggcaa
    14281 atttatgttg cataatgata ctgtatctat aattgtgcat cgcctcagtg taacttctac
    14341 tcttcaaaac ttcaaacagg gtgaataagt cgatctctcg tttctgataa agtttgcatc
    14401 tcctgaagat tgtcaggaac acgcaattag cgcttgaatt cattgatcga gtgtgtcaaa
    14461 ccacttagca gttcgacata cgtaagtgtg tatccacaat agagctgcac tgtgcaacta
    14521 cgtaaaacca caaattagaa aatttataca aggctatgct gaagtcagaa caatatcaac
    14581 acccgtcatc gcaagcctat gccactcagt caaatgaaga tgaagggggg ctaaatttag
    14641 gtcaagtggg agcatctctc cgtcgccgtg cattgttaat cgctggtgta acaggtgtag
    14701 tggctacagc agcagtttta aaggcagaaa cagatcctcc agtctatgaa ggaaagtttg
    14761 aaattttaac caaaccagtg actggagaaa gtcgcgcagt cgctaacgtt cctcaaacct
    14821 tggagtccca aggcaaagga atagcacctc ccgaacaagc agaacccgtt gccacaacaa
    14881 ttcaagttct caaaagccgt gggatgctag atccagtcgt taaaagactc caagttaaat
    14941 accaaactaa atatccaaaa ttggattacc agaaaattac aaaactttta gaaatagaat
    15001 cacaacaaca aaatatttta gaagttaaat ttactagccc agacgaggag ctagtccgag
    15061 atactttaac tttgctgaaa gatgcttaca ttgcctatag tttaaaagaa cgtcgaggcg
    15121 aagttcagca ggcaattaat tttgtgagag aacaaaaaac tcctttagag gcaaaagtta
    15181 gagcttggca aagaaaactg caaaaaattc gacaagagca taatttggta gagccagcac
    15241 agaaagctca agaagtatcc gctcaaattg ctactttgac gcaacagcag gcagaaaatc
    15301 gcgtacagct agaacagatg atagcgagtt accaggactt gcaaagggag ttggcgcaac
    15361 aaccagggga tagggctggt aactcagtgc tgagtgaaaa tgttcgctat caaaagatat
    15421 tagatcagct gcaaacagtg gaaattgaag tgaaaaaaga tgcagctaaa ttcacagata
    15481 caaatccaag tctgcaattc ttgcaggaac agcgagcaaa tttactccca atgctaacgg
    15541 ctgaagaaaa tcgcgtcaaa agagattatc aaagccgcat ccgagcactc caagctcgcg
    15601 atcgcgcttt gggtgaaaaa attagctact ttaacaccta cctgagaaat ttagccagtg
    15661 ttattcgtca atacgatgat actcagaggg acttaaagat tgttacggat ggtctggttc
    15721 aatttacagc caaagaacaa gcactgaaaa tcgaacaagc tcaatcattg ccatcatgga
    15781 agttacttga cccccggctg gcagaagtga cagagcctga ggctgttaaa gacagtacta
    15841 aacggaattt ggctttggga acgttgttag gtttactact tggtacaggc gcagctttgg
    15901 tgatagataa gctgagcaac gttttttaca catctaaaga cctaaaagaa gcgactcgat
    15961 taccactgtt gggagtcgtt cctctaagaa aagagcttgg cgcaatggct tggcaagaag
    16021 cagcaagtga ggagcaacaa gcagcccgtg cttccttctt tgaagttttt cgctctctgt
    16081 acactaacat tcttcttcta agttcagatg ctccgattcg ttcgctagtt attagttccc
    16141 caggacaaga agatggcaag acaaccgttg caatacactt agcacttgca gccgcagcga
    16201 tggggcatcg agttttgcta gtagatgcca atttacgcaa ccctaccata cacagtcgtg
    16261 ttggtctaat gaacattcag ggactaaccg atattattgc ccaagactta gactggaata
    16321 atgttattga gcgatcgccc ttagaggata acttgtttgt gttgagtgct ggtccaacgc
    16381 caccggactc cattcgattg cttgcatctc gtaaaatgca ggatttgatg aatgacttac
    16441 aatccacgtt tgatttagtc atttatgaca catcccctct agttggtttt gcagatgcta
    16501 acttgctagc agttaacaca aatggtcttg tactcgttgc tgggttgggc aagctcaaac
    16561 ggactatgtt ccagcaagca ctagaagaac tccaggtctc gggtacgcca attttaggag
    16621 tcatagccaa caaatcaaag gatgccacta caacctctta cagctactat cagcaatatt
    16681 acaagagtat gagcgctgaa agagttggac acaacgaagt tttagactcc attaattctt
    16741 agtctacttc ttgtaggaga aagaatggag aaaaacgtta atgggtaata gtttatggtt
    16801 gcgctatggc gcaactataa actcagtatt tttctaaata caagcaccca ttgactcgtc
    16861 acttttcagg agatttcaaa gcccgatcta gaatttggcg agcttcttct gcttttgttc
    16921 ttgcttcgtg atagcgtaga ttagcttgag cataattttt gagaacttta aaaccttctt
    16981 taagacgagc gatctcctct tctgtcaccg atttatctaa gaacaaaaca tcaactgcct
    17041 tgcgaatttc cagagcttcc gtgcgtgact cttgcacttt tagtttgagc gtagcaagat
    17101 tgcttaaaac ttggacagct tgagaaatag catcttcatc actatttgtc tcaactgggg
    17161 cttctttcag ttcaatcagt tgttgaggac caaagccatc ttctaattct gtaggaagtt
    17221 taccttcatc catcagtttc atcaactgat ccattgcttt ctcacgggct tttgtggaat
    17281 cttttccagg aacggtaaga acaatttctg ggctttgagc aagagtgtat tgaaccatgg
    17341 tagggcaaaa attttgctat ttatcaagcc ggggataata attttaacgc aaaacaagct
    17401 aaaaaatcag cagcagcaaa accagataaa gtcactaaac gatttatttt ggcatatgca
    17461 aatgattttt tagcttacct aaatataatc taacctgcgt tggtttgcga tcgcctgttg
    17521 tcgtttgcga gcctactcct gcttcatacc tattctggct ttatttgtaa tattttgtca
    17581 cacaaaaccg tttttgtgtt acatttccgg caacgagagg tttgtaaaat tcctataaat
    17641 cgtctctaaa gtttactcta gcaagcattt aggtaattag cagttgatat gagaaggtaa
    17701 ttttctactg agcacaaagt aaatttttta ccttaactgc caaaacacta ccgaaaaaat
    17761 aaagatatga tatactgctg caagatggaa acataagtgt agttgttgtc aaggttaata
    17821 ctagtaatga cgcacaacca tcgaaagagt gacttcgggg gctctaccag ctaatgttac
    17881 ccgaggaatg actcatggct attatcagcg ttaccagtgc cgcagacagt ggagctggtt
    17941 ctttaagaga ggcagtcgca aatgctcaac caggagacac gattaaattt gcctccaatc
    18001 ttgctaacga caagataatt ctcactagtg gtgaaattgg tattctcaag cctttaactt
    18061 ttgatggctc agatgcatca aatttagcaa ttagtggcaa tcaacagagc cgtattttca
    18121 atatcggcaa ccaagagaac cgtattaacg tgactatcaa ggacttggcg ttcgtagatg
    18181 gtagggcagt tgctggtact acgagtgacc aggattttgc agcaggaggt gctatccgga
    18241 ttcatgactt cagcgatgtc gtggttgaaa atagtctctt taagaataat gttggtgagc
    18301 ggagtggagc cattcgcgtt ggctttggtg gctccctcac tgttcgtaac agtacgtttg
    18361 acggcaatga tggttcgatc gccaatgatg accacagtgc gggagcaatt tccacctatg
    18421 gctccggagg tatacctgac ttcgatccgg gtaatggctt cgtcaagatt gaaggcagta
    18481 cttttaccaa taacaagggt agtgaaggtg gagctgtcta cagcctactt ggtcctctga
    18541 ctattgaaga ttccactttc aagaataatg aaagtactag agatgggggt gctgtcttca
    18601 ctgatggagc tgacaaatcg gaaaaagatg acctaggtgg tgaaattact atccgtagga
    18661 gtgtttttga aagcaacaaa gctaagggtc ttggcggtgg gttatcccta tggacgtata
    18721 accccgataa aattctgatt gaggacagtt caatcgttgg caattcagta acctatggag
    18781 gaggagctga aaataactcc aagggtggcg gtctacgtgt taacagcggt tacttgacta
    18841 ttcgcaatac aaccattgcc aataacacat cagagcacca aggtggagga gcttggatcg
    18901 atggcacttt aacagttaac attgaaaact ctactttctc tggtaactcg gcgagggacg
    18961 atatgggtgg agctcttacc ttaaatacgc cggataacac acccgtaaat attacaaata
    19021 atacttttgt caacaactca gcaggacgat acagcggagc tatttggtca aacgatcgca
    19081 acagtgatga cattaccctg accaatacta tcttcgctgg taacactgca tctccacaac
    19141 agatgcatac gaattaccag ttgaaagatg gtggcggtaa tttcgtagaa aaaactgtag
    19201 gcgacctagg accaaaagtc acagcaactg ctacatacgt agatgacctt aagcttagcg
    19261 acactctcca attggtggga aaccgtttga tgtacgtgct tgagagcggt agtccagcta
    19321 tcagtggtgg aactacaaat ggggctacta caaaagacca acgtggtgtt ctccgagaca
    19381 gtcaacctga cgccggtgca tttgaatttg ttcccaacgg acagattcca gtaccgagca
    19441 gtgcgagtag caacaaaggc aacaacaaaa cggatgacta tcaagttatg actcctgtcg
    19501 atagctttat tgactcccaa aagctactta ttgacctgcg ttcggttgac ctcgatcgag
    19561 acggtaaggt cgatagcaaa gtctccgtca ccctcgacga cattaagagt gacgctttct
    19621 acaataactc tgcaggcttt tataaaatcg ctagtgcaga tggagcagtt ctcgattcca
    19681 tgactaacaa actgatttat ccggaagatc ctggctatgc ccaagcagca ctgaaacaac
    19741 gggtatctgg gggagagata aatcggaata caggcaagct tatcagccaa tttgatggtg
    19801 gagctttgta cgcaccttat ctgatcgcta atggtacagt agagcagttt ctcaacaatc
    19861 catttggtaa tctccaagca ttctttagcc aaggagcggc aaatcttgac aagacaaatc
    19921 atgttaagct gttagacaac aaccagtttg ggtttgaaga cctactcaat gcacaagatc
    19981 cagatttcaa tgacttgact tttaaagtga agatacaaag ttcttgacaa acagcagcgc
    20041 tcggaaaaag caattcgcaa atatttaagt gtcattgcaa ttgcaagctt gttattagct
    20101 agctgctcgc aaattcctgt aaatgggaac ctcctataac gtacctacac cgtactgagt
    20161 accagtcggt gtaggtactt cattgctgca tacgtcagaa ctaacgccat cggcactcaa
    20221 tgaaaactca aattctatac tagaaacagt aagcttattt ttcattgcga gggaagagcg
    20281 atggctccaa atcccaccat aatgcgaact gtagaacaat tgggttatcg cgtcaccgtt
    20341 ggagacgtgg caactcaagc tggtttaaat gttgcagagg caaatcaggg tttactagcc
    20401 ctagcttctg atgctggcgg acatctacaa gtttcagaga ctggtgatat tgtttaccta
    20461 tttcctaaaa actttcgaga tattttacgt aataaatact ttcaattaag attgcaggaa
    20521 tggtggcaaa aaatttgggg aattattttt tacctaattc gtatttcctt tggaattttc
    20581 ctcattgctt ccattgctct gataacgctc tcaattatct taattatctc tgccgccaac
    20641 tcggaccggg atggggatga caggggtagc agttttagtt tcttttattt ccccgatatc
    20701 ttttggtatc tcagccctga ctacgatacc caccaacgac aaagacggcg agaaaaaagc
    20761 catctcaatt tctttgaagc cgtgttttcg tttttatttg gtgatggtaa ccccaatgcc
    20821 aatttagaag aacgccgatg gcaagaaatt gctagcgtca ttcgcaagaa tcgaggtgcg
    20881 atcgttgccg aacagattgc gccttatctt gatgacatag gagaaggttc tgcaaaagag
    20941 tacgaagatt atatgttgcc cgttctgact cgttttaacg gacaacctgc agtcagcccc
    21001 gaaggagaaa ttgtctatta ttttccagaa ttgcaagtga gtgcagtact acagggcggt
    21061 atcccgtcgc agggatctgc caaatccgta aggagaagtg atgctcaaca gcattatgac
    21121 cccctatcag accatctcat ggaattttct tggcgattca gtgcagcaac atcagggcaa
    21181 attatgttaa gtgctgggct cggagtcgca aatttcgtcg gtgcgttagt gttgggaagt
    21241 ttgttaagag atggcgtagt agcagcacag ctagggggat tggttgcctt tgttcaagga
    21301 atttactggc tgttattagc ttatggaacg ggttttcttg cgatcccctt aatccgatac
    21361 ttttggattc aatggcgcaa cagcaaaatt agcagccgca accgcgttcg acaggagcgt
    21421 gctagattgt tagcagatcc aaatacgcaa ctggagcaaa aaatttctta tgcccgtcaa
    21481 tttgccacag caaaagtcat cggtactgac gatttagctt actctactga aacggatttg
    21541 ctagaacaag aatttaagaa gaatgatgaa ttataaatta tgaattatga attatgaatt
    21601 atgaaatttt taattcagca ttcataattc ataattcaat ttacctttga actgactcat
    21661 aaataagtca tagtagaatc cttgtttttg catcagttcg tcatgagtac cagtttcaat
    21721 aatttcacct gccttaagca ccagaatccg atccgcattg cgaattgtac tcaaacggtg
    21781 ggcaatcaca aagctagtac gtccttgcat taatcgatct aaggcttgtt gaatcttctg
    21841 ttcggttctg gtgtctatat tgctagtcgc ttcatccaga ataaccatgc ggggattttg
    21901 aaccatcatg cgggcaatgg ttagtaattg ccgttgtcct tggcttaaat tactgcctcg
    21961 ttccgtcagc attgtattgt aaccatctgg cagatgcaaa atgaattcat gagcattggc
    22021 ttgtttggtc gcctcaatac agtcctgctc ggtggcatct aaacgggcat agcgcagatt
    22081 gttcataact gtgtcagaga acaaaaatgc ctcctgtaac acaatgccaa tttgccgccg
    22141 cagactgtcc tgttggaagg tggcaatgtt atgcccatca atcaaaattt cgcccccatc
    22201 gaggtcgtag taccgagtaa tcaggttgat aatggtgctc ttccctgctc cagtcggtcc
    22261 gcacaagcca attttttcgc ccggtctggc ttcaaagctg ttgtgcttca ggataggtct
    22321 accttgaata tagctaaagt ttacatcgcg agccagtacg tggccctgaa ttggtggcat
    22381 ttctggagca ttgggctggt ctacaatggc tggtcgttca tccaaaatgc taaaaatgcg
    22441 ctcggcggcg gcgcttgcag ctagcaaagt atctaggtta ttaccaagac tcgcaattgg
    22501 aatcgagaac tgacgagtgt attgtaagaa agtagcaaca accccgatat tagcctctcc
    22561 tcgcaaggtc agtagtcccc ccactagtgc tactaaagcc acatccaggt tcgtcaaaac
    22621 gagggtaacc ggaccgctta ctaatgctag caagcgtgcc ttgacacctg ctaagcgagc
    22681 taaatgactg atatcctcaa aggttgcgat cgcctcttcc tgctgaccgt aagcaattac
    22741 caccttctgc ccgctgacag tttcttccaa taagctgt
//
