LOCUS       NZ_JHEG04000001        42403 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2844326
            Orig. end                         :: 2886729
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..42403
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-v"
                     /region_number="13"
                     /rules="(APH and HopA1)"
                     /tool="antismash"
     cand_cluster    1..42403
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(APH and HopA1)"
                     /kind="single"
                     /product="lanthipeptide-class-v"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42403
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[20000:22403](-)"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..22403)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="1"
     gene            complement(270..2420)
                     /locus_tag="HC643_RS11315"
                     /old_locus_tag="DA73_0400011315"
     CDS             complement(270..2420)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016867482.1"
                     /locus_tag="HC643_RS11315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011315"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_038075269.1"
                     /transl_table=11
                     /translation="MYKSILNQSVSPQTIAIIGGGLSGSLVAANLLRNATIPISIKLIE
                     RNCEIGKGVAYGTRVDCHLLNVPAGKMSAFPDESDHFLKWLHANGYEQVTASTFVPRTV
                     YGSYIQAILQEAQAKAQAGVEFERIVGEAIYIDTTTYSVRVYLNNGRRLQVQKAVLALG
                     NFPASLPEPIAALGNPNPYVKDAWAEDAIANLSPEDSILLVGTGLTMADAVVALHQQGF
                     KGQIHAVSRHGLMPCHHKPTTPYAAFLNLETAPKTARGLFHLVRQEVKVASDRGQDWRG
                     VIDALRPVTQELWQALPFKEQKRFLRHVKAYWEVHRHRIAEEIAEVLDTAVQSGQLRHY
                     GGRIQTCQEFEKGVNVTIRERGTSADIVLQVSRIVNCTGSNCNYRRLQHPLLSSLQEQR
                     LFRSSTLSIGIDTAANGALIDADGNVSELLYTLGTPRKGNLWETTAVPEIRVQAVSLAQ
                     ELLKSLDSKLYPAIEVSKLPKPVMLFRQLFDKESSTYTYLIADPETKEAILIDSVLEQV
                     ERDLQILRELGLTLRYCLETHIHADHITGSDKLRELTGCLSIVPEKAATIGADSYIADR
                     AILELGSVRIQAIATPGHTDSHMAYLVNGTHLLSGDALFIRGCGRTDFQNGDAGLLYDV
                     VTQKLFALPEETFVYPGHDYQGRTVSTIGEEKSWNPRFAGRSRKQFIELMNNLNLPYPK
                     KMLAAVPANQFCGKISMWDYQI"
     gene            3144..3803
                     /locus_tag="HC643_RS11320"
                     /old_locus_tag="DA73_0400011320"
     CDS             3144..3803
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012409957.1"
                     /locus_tag="HC643_RS11320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011320"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_038075188.1"
                     /sec_met_domain="Methyltransf_3 (E-value: 1.2e-79,
                     bitscore: 265.2, seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 7.7e-05, bitscore: 21.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNQTLGLEKNLYEYLLSVSVQEPEILTQLRQETAQHPMSQMQIA
                     PEQGQFLALLVQLMNAKKTLDIGVFTGYSSLVVALALPPEGKVVACDVSEEYTAIARRY
                     WQQAGVANKIELHIAPAIETLDRLRAQGETFDFAFIDADKSNYDNYYEQALQLVRPGGL
                     IAIDNVLWSGRVADPQVQDNRTNYMRTFNEKLYRDSRVTISLVPIADGLTLALKKG"
     gene            complement(3993..4889)
                     /locus_tag="HC643_RS11325"
                     /old_locus_tag="DA73_0400011325"
     CDS             complement(3993..4889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010994560.1"
                     /locus_tag="HC643_RS11325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011325"
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="WP_038075191.1"
                     /transl_table=11
                     /translation="MSLVVAALYKFVSLPDFAEKQQPLLSFCQAHDIKGTILLAPEGIN
                     GTIAGSRQAIDSVLSFLRSDPRLEDLEHKESHAESPPFQRMKVRLKKEIVTIGLSEVNP
                     NEQVGTYVDPKDWNTLLNDPEVTVIDTRNDYEVSIGTFQKAQNPNTKSFREFPEYVFHQ
                     LDPKQHKKVALFCTGGIRCEKASSFMISQGFKEVYHLKGGILKYLEEVPESESLWEGEC
                     FVFDERIAVRHALEPGTYDLCASCGHPISEADKTSPQYEKGISCPHCFETLSEGKKERQ
                     MEKQRQIELANRRSVNG"
     tRNA            4975..5047
                     /anticodon=(pos:2849334..2849336,aa:Ala,seq:tgc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="HC643_RS11330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="DA73_0400011330"
                     /product="tRNA-Ala"
     gene            4975..5047
                     /locus_tag="HC643_RS11330"
                     /old_locus_tag="DA73_0400011330"
     gene            complement(5088..5483)
                     /locus_tag="HC643_RS11335"
                     /old_locus_tag="DA73_0400011335"
     CDS             complement(5088..5483)
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070497 -
                     6-carboxy-5,6,7,8-tetrahydropterin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTPS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015215049.1"
                     /locus_tag="HC643_RS11335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011335"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_038075194.1"
                     /sec_met_domain="PTPS (E-value: 1.8e-30, bitscore: 104.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKWKLVTEFTFDSAHYIRDYDGPCGRLHGHTYKVKIEATSSKLH
                     SSQYCPHEVMVADFRTLRWAKQDVKKGGLDHCVLNEVIPPEYETTAEMIAKYIYDETKK
                     RVPPGVHLKVAVSETPNSWAEYEDDDD"
     misc_feature    5574..5587
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.13"
                     /tool="antismash"
     misc_feature    5574..5588
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.1"
                     /tool="antismash"
     gene            complement(5725..6294)
                     /locus_tag="HC643_RS11340"
                     /old_locus_tag="DA73_0400011340"
     CDS             complement(5725..6294)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0070064 - proline-rich region binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017746985.1"
                     /locus_tag="HC643_RS11340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011340"
                     /product="SH3 domain-containing protein"
                     /protein_id="WP_038075197.1"
                     /transl_table=11
                     /translation="MKNQTSLLKIFLISLSLSSFNFVPTAFAGMGNQKILAQQTSCTVT
                     NIQTGQLALRSQPNGKSRAGLNNNNSVQLLRQGSEPWVYVRVLRGPNIKVNGLEGWVNS
                     NYLICDEKTASSPESCKVINITQGQLALRSTPNGKSKAGLNNGNVVKWLRWGAEPWVYV
                     RVVNGPNTKVSGLEGWVNSDYLFCDV"
     tRNA            complement(6436..6508)
                     /anticodon=(pos:complement(2850799..2850801),aa:Val,
                     seq:tac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="HC643_RS11345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="DA73_0400011345"
                     /product="tRNA-Val"
     gene            complement(6436..6508)
                     /locus_tag="HC643_RS11345"
                     /old_locus_tag="DA73_0400011345"
     misc_feature    6567..6581
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.37"
                     /tool="antismash"
     gene            6598..7260
                     /locus_tag="HC643_RS11350"
                     /old_locus_tag="DA73_0400011350"
     CDS             6598..7260
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017311006.1"
                     /locus_tag="HC643_RS11350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011350"
                     /product="metal-binding protein"
                     /protein_id="WP_050045682.1"
                     /transl_table=11
                     /translation="MPSGRTHDRITLWALPLVTGVTFWQTKSGNLTLLVAGGFLFGGLM
                     FGPDLDIYSRHYQRWGFLRFIWLPYQKSLRHRSFLSHGPIIGTTLRVIYLSTLVAILGI
                     LVIVVGEKLWNLQLDWQILHKNTANTLFNYSRELLALFFGLEIGAMSHSLSDWSGSAYK
                     RVKKQGVSGLLPRGKMKKSKVKRGTRRQGGAGDKGTRGTRKKGSREAGEQGSREAKK"
     gene            7335..8153
                     /gene="mazG"
                     /locus_tag="HC643_RS11355"
                     /old_locus_tag="DA73_0400011355"
     CDS             7335..8153
                     /EC_number="3.6.1.9"
                     /codon_start=1
                     /gene="mazG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016867891.1"
                     /locus_tag="HC643_RS11355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011355"
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="WP_038075200.1"
                     /transl_table=11
                     /translation="MKNSDILAALQELIDVVAKLRSPEGGCPWDLEQTPQTLTPYVIEE
                     AYEVVDAINSGDKNAIAEELGDLLLQVVLQAQIASEYQQFSLKEIAEGISQKLIRRHPH
                     VFGDISVQNVDEVRQNWEKIKAEEKGKPAPESQKLSYKLQGYTRKLPPLMATMKISRKA
                     AAVGFEWENLDGVWDKFNEELAEFKEALAHETPERQQEELGDLLFSIVQLARWNNLDPS
                     EALQGTNRKFIQRLEQMEGFANRPLSDYTLEELEAFWQQAKAVERMETGG"
     gene            complement(8301..9773)
                     /locus_tag="HC643_RS11360"
                     /old_locus_tag="DA73_0400011360"
     CDS             complement(8301..9773)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016863414.1"
                     /locus_tag="HC643_RS11360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011360"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_038075203.1"
                     /sec_met_domain="Aldedh (E-value: 4.7e-193, bitscore:
                     640.7, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTALKLDNQVKIGPTNLLINNEWVESISGKRFETINPATGDVIC
                     SVAEADAADVDKAVHAARAAFNKGEWRTMSATRRGELLYKLADLIEQNKEELAQLETLD
                     NGKPISESMNADLPLVIACYRYFAGWADKVQGKTIPINGPYFCYTRHEPVGVVGQIIPW
                     NFPLLMQAWKLGPALATGNTVVMKTAEQTPLSALRLGELMIEAGFPPGVVNILSGYGPT
                     AGAAISHHMDIDKVAFTGSTEVGHLVMEAAAKSNLKRVTLELGGKSPNIVFADADMDEA
                     IEGAHNALFFNQGQCCVAGSRLFVEEKCYDEFVAKSVERAKQRTVGNPFDLNTKQGPQV
                     DKEQFNKVMHYIEAGMREGARMLCGGNQVGDKGYFIAPTIFADVQDRMEIARDEIFGPV
                     MSIIKFKDIDEVIQRANNTMYGLAAAVWTKDITKAHAIANNVRAGTVWVNCYDVFDAAA
                     PFGGFKQSGIGRELGEYGLQQYTEVKTVTIKL"
     gene            9892..11181
                     /locus_tag="HC643_RS11365"
                     /old_locus_tag="DA73_0400011365"
     CDS             9892..11181
                     /EC_number="1.2.1.41"
                     /GO_function="GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017746979.1"
                     /locus_tag="HC643_RS11365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011365"
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="WP_038075274.1"
                     /sec_met_domain="Aldedh (E-value: 8.7e-14, bitscore: 49.7,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENIIAVAQKTRRAALKLAVLSTEAKNQAIEAIAQALESAKDEIL
                     QANLADCETSIAEGIAEPLYKRLKLDEHKLRDAIAGVRDVGKLADPVGTVQIHREIDTG
                     LILKRLTCPLGVLGIIFEARPEAAIQIVSLAIKSGNGVILKGGKEAVRSCETIVKAIKQ
                     GLSQTAVNPDAVQLLTTREEILQLLKLDKYVDLIIPRGSNSFVRFVQDNTRIPVLGHAD
                     GVCHLYIDKAADLEKAVAITVDAKTNYPAACNAIETLLVHANIAPKVLPQISEALQHLK
                     VELRGDERTRQILPNILEATEQDWETEYNALILSIKIVDSLEEAIAHINEYGSKHTDGI
                     VSEDEEAAQTFLALVNAAGVYHNCSTRFADGFRYGFGAEVGISTQQMPPRGPVGLEGLV
                     TYKYQMSGNGQIAATYTGANAKAFTHRDLL"
     misc_feature    complement(9915..9924)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     misc_feature    complement(11217..11233)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.55"
                     /tool="antismash"
     misc_feature    11217..11233
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.29"
                     /tool="antismash"
     gene            11454..13979
                     /locus_tag="HC643_RS11370"
                     /old_locus_tag="DA73_0400011370"
     CDS             11454..13979
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017746978.1"
                     /locus_tag="HC643_RS11370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011370"
                     /product="PAS domain S-box protein"
                     /protein_id="WP_038075206.1"
                     /transl_table=11
                     /translation="MRDEDKTKEQLIQEIAELRQRVSSLETLATQQQKAETVLYDRAQR
                     QVQREQALNRVIQSIRNSLDIKTIFSTAAREIAHLIHADRAEIVQYLPERQLWLNVTDY
                     RKNLDLPSALGLEIPDSYNEIASRLKRLEVVVIEDASSNYIDEINRNFAEIYSGAWLLV
                     PLHVNSSVWGSLSIIRSCQSSPWQQEDIELTCAVADQVAIAIQQSTLYEQVQSELRERK
                     RAEAAIYFQAHLLSAVEQGVIATDLDGKIIYWNRFAETLYGWSAQEAIGQNIMDVVVTD
                     TLREQGLKIMSELQQGKSWSGEFPVQRRDGTHFCVLVTDAPIYDDQGVLIGVVGVSTDI
                     SERKQIEEKIREQAALLDIATDAILVRDLNHKILFWNKSAERLYGWKAQEALGQNAQVF
                     LYREIPLQLQEAINQVHTTGEWYGELNKVRKDGKDIIVESRWTLVRDESGNPKSILTVD
                     TDITEKKQLQTQFLRAQRLESLGTLASGIAHDLNNILSPILLSAQILKMKLGNEQHNQL
                     LETLELNAQRGADLVKQVLSFARGVEGQRTVLQMKHLIIEIQQFAKQTFPKSIQFICKT
                     ASNLWTVYGDATQLYQMLMNLVINSRDAMPKGGILDISADNFFIDENYAKMNLEATVGP
                     HIVISIRDTGTGMSPEILDRIFEPFFTTKAVGQGTGLGLSTVLGIVKSHGGFINVSSSV
                     GKGTEFQVFLKAVMANEIQSIENLPLPTGNGELILVVDDEAKIRDITKTALENYNYKVL
                     IASDGIAAISMYAQNVSDIRVVLLDMMMPTLDGMTTIQTLKKINPSVKIIASSGLQENQ
                     LIAESLGIHKFLQKPYTMKQLLQIIQNLL"
     gene            complement(14082..15506)
                     /locus_tag="HC643_RS11375"
                     /old_locus_tag="DA73_0400011375"
     CDS             complement(14082..15506)
                     /EC_number="5.4.4.2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008909 - isochorismate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017311242.1"
                     /locus_tag="HC643_RS11375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011375"
                     /product="isochorismate synthase"
                     /protein_id="WP_038075209.1"
                     /transl_table=11
                     /translation="MTVSQCRADFFVYNKELYHFLWAIQQNCLRKNCTQIASVSIEIDP
                     VDPLVVFSKLGQPQQINFYWENKSKKEAIASFDAAAKLEITGKNRFKASEDFIKDCLEK
                     TVCFSEIARAFSKPLFLCSFSFFEEPSQADYPFPSATIFLPCWQVAVKNNRYTFVANIP
                     MDANVDIQKILQVLWSKLETISSLNSLEYSFLPLKIVQPKLSQQYVANPEQFKRSVSGA
                     LESIQSKRLRKVVLADALDVRASIRFNLLQSLNNLRQLHSNCCIFSISNGKGQNFIGAS
                     PERLIGIDKQQLITDALAGSAPRGKTPAEDAVNASRLLSSEKERHEHSLVIDFITQRLS
                     QLGLLPQVLRPRLRQLSNIQHLWTPINAIVPNNVHPLSIVAQLHPTPAVAGASREIACR
                     EIRRYENFERGLYAAPLGWVDSEGNCEFIVGIRSALIDGDRARLYAGAGIVAGSNPDKE
                     LAEVQLKLQALLRALV"
     misc_feature    15494..15506
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            15785..16684
                     /gene="menA"
                     /locus_tag="HC643_RS11380"
                     /old_locus_tag="DA73_0400011380"
     CDS             15785..16684
                     /EC_number="2.5.1.130"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042372 - phylloquinone biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="menA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017746976.1"
                     /locus_tag="HC643_RS11380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011380"
                     /product="2-carboxy-1,4-naphthoquinone phytyltransferase"
                     /protein_id="WP_038075214.1"
                     /transl_table=11
                     /translation="MTTKLISYPKNKLWMAALKPPMYSVAIMPIWVGTAVAFAETKTFH
                     GAVFSTFVAAAICILAWENLSNDVFDSETGIDKNKHHSLVNLTGNKTLIFWVGNLFLLL
                     GLLGILAIAWWQQDLTVIGIILLCCALGYTYQGPPFRLGYQGLGEIICFFAFGPLAVSA
                     AYYSQTANWSWRALVASVVVGIATSLILFCSHFHQVKDDIAAGKRSPIVRLGTQRGAEV
                     LQWFTGSIYAIAFIGVIWGLFPSWTLLSWASLPFARKLCHHVQTNHNQPDKVNNCKFIA
                     VSVHFWCCLLFGLGFVLG"
     gene            16962..17963
                     /locus_tag="HC643_RS11385"
                     /old_locus_tag="DA73_0400011385"
     CDS             16962..17963
                     /EC_number="4.2.1.113"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017746975.1"
                     /locus_tag="HC643_RS11385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011385"
                     /product="o-succinylbenzoate synthase"
                     /protein_id="WP_167844659.1"
                     /transl_table=11
                     /translation="MHYQFQFRPYQRRFVRSLTTSHGVWETREGIILKLTNDLGGVGWG
                     EIAPISWFGSENQEEALSFCRQLPEAIADETIFSIPDELPACQFGFESAFWGLRAENWG
                     LGDKGVSPTLSLNPKSLTYSALLPAGEDALEVWRTLWQGGYRTFKWKIGVYPVTEELRI
                     FKRLAQTLPSLTKLRLDANGGLSYEEANLWLWTCDNLKTDSTLNLEIEFVEQPLSVDKF
                     DSMLELSHCYHTPIALDESVATLHQLVACYQKGWREIFVIKPGIVGSPFRLRQFCLECE
                     VDAVFSSVFETSIGRKPALQLAVELSRYNRAVGFGVNHFFAEEEEIWLENLW"
     gene            17957..19435
                     /locus_tag="HC643_RS11390"
                     /old_locus_tag="DA73_0400011390"
     CDS             17957..19435
                     /NRPS_PKS="Domain: AMP-binding (50-368). E-value: 6.8e-41.
                     Score: 132.1. Matches aSDomain:
                     nrpspksdomains_HC643_RS11390_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017315792.1"
                     /locus_tag="HC643_RS11390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011390"
                     /product="2-succinylbenzoate--CoA ligase"
                     /protein_id="WP_167844660.1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-44, bitscore:
                     150.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVATLEYIVEQSLRVPSDWLICDSDNLFPLIIKQRYLELMQFSHW
                     KTPPKILLAEPEPVKFLASFLAACQANCPVFLCNPGWGQQEWEQVFDLVKPDIIWGVNH
                     KVSELCKEQHSFPPSPCPSLSPSPLIMIPTGGSSGKIKFAMHTWETLMASVRGFKEYFQ
                     VDNINSFCVLPIYHVGGLMQFMRSFTTGGQLAILPFKELESGQNYNIQPQEFFISLVPT
                     QLQRLLQNAELTQWLAQFQTVLLGGAPAWSELLEAARCHKIRLGLTYGMTETASQIATL
                     LPDDFLKGKDSCTRLLPHAKVNIYNEKGEILKPNQTGNIKISSQSLALGYYPNIQTNWE
                     FLQTDDLGFLDEQGYLHISGRSSDKIITGGENVYAIEVESAIRGTQMVTDVCAIGVPDP
                     VWGQAITAIYIPKNSNISYLQIKELLKNKMSRFKIPKNWIKVDSLPRNSQGKINRLQVQ
                     ELASNFLQKNLRQNQVLTPPKHTNQHSGCDRATG"
     aSDomain        18107..19060
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS11390_AMP-binding.1"
                     /evalue="6.80E-41"
                     /label="HC643_RS11390_AMP-binding.1"
                     /locus_tag="HC643_RS11390"
                     /protein_end="368"
                     /protein_start="50"
                     /score="132.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ILLAEPEPVKFLASFLAACQANCPVFLCNPGWGQQEWEQVFDLVK
                     PDIIWGVNHKVSELCKEQHSFPPSPCPSLSPSPLIMIPTGGSSGKIKFAMHTWETLMAS
                     VRGFKEYFQVDNINSFCVLPIYHVGGLMQFMRSFTTGGQLAILPFKELESGQNYNIQPQ
                     EFFISLVPTQLQRLLQNAELTQWLAQFQTVLLGGAPAWSELLEAARCHKIRLGLTYGMT
                     ETASQIATLLPDDFLKGKDSCTRLLPHAKVNIYNEKGEILKPNQTGNIKISSQSLALGY
                     YPNIQTNWEFLQTDDLGFLDEQGYLHISGRSSDKIIT"
     gene            complement(19487..19933)
                     /locus_tag="HC643_RS11395"
                     /old_locus_tag="DA73_0400011395"
     CDS             complement(19487..19933)
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009459014.1"
                     /locus_tag="HC643_RS11395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011395"
                     /product="thioesterase family protein"
                     /protein_id="WP_038075217.1"
                     /sec_met_domain="4HBT_2 (E-value: 8.5e-20, bitscore: 70.2,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFTYNHTVRFRDTDAAGVVYFANVLAICHEAYEESLATFGMNLK
                     DFFTNPSIAFPIVHANVDFFRPLYSGDNLVIRLIPQQLSGDRFEVGYEVIVGEVVAAKA
                     ITRHVCIDTSSRTKTELPENMKQWLETNRKGAESIERRKSRETI"
     gene            complement(20001..21101)
                     /locus_tag="HC643_RS11400"
                     /old_locus_tag="DA73_0400011400"
     CDS             complement(20001..21101)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: HopA1"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017746972.1"
                     /locus_tag="HC643_RS11400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011400"
                     /product="T3SS effector HopA1 family protein"
                     /protein_id="WP_038075220.1"
                     /sec_met_domain="HopA1 (E-value: 1.1e-60, bitscore: 203.1,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKSSKPLLKSLLDIASNIQIESSFCISHPKYQPFALPQQVAGRF
                     QQTSPSLQQKYLSLLLRNFLHGIYYNGSLKKILIEKNGICPSNLPHKSLESDSQFKIDL
                     PFYEQLHSSNHGVGYFDSGWEVLRQEPDGSMAVAKGGLTLYVERPANLETMVQSTKVGE
                     VTAIWMPKNRIENGFYIAVSNVGQDLQVNLNGDFGVGRIYFNITPTGAIALMNSLTRLL
                     NSAEIPFSFQVLHNRSSYGRYDSGILYFEREDYLAVRKILKAVYVKHQAHFHKDIPLFT
                     KFLAPGLGLAEEPSQKFASQESFGMNRCQIVANALLESWENGDNSTEKRMSAIYQHFAR
                     LGIDLQRPYLNPDSEDIYSPLDRTNR"
     misc_feature    complement(21156..21170)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.42"
                     /tool="antismash"
     gene            complement(21165..22403)
                     /locus_tag="HC643_RS11405"
                     /old_locus_tag="DA73_0400011405"
     CDS             complement(21165..22403)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: APH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016863106.1"
                     /locus_tag="HC643_RS11405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011405"
                     /product="phosphotransferase"
                     /protein_id="WP_038075223.1"
                     /sec_met_domain="APH (E-value: 1.7e-09, bitscore: 36.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTSLSSHNVIQDLQEAGLCSSEEGVSTDSELPQSSKKNFNLLVT
                     LKGNRQLLVKQERHIDNDGKPQEFFNEWLFHQLLERFPALGSISAIASLVVYFDRKKSI
                     LVRNYLKDYQDTASFYRQNLRFPNSIATAIGTSLGLLHRATFKHHEYRDFMATAPEGEY
                     RYHLYNPAQGLGSIGPEIISRVPTNALKFYTLYQRYETIEGAIAELSYEWKPCCLTHNE
                     LRLDNILLHSKWEQLDNCLVRLIDWEACAWGDPSFDLGTLVADYLAIGLESLVVDPSLD
                     LDESLHLSAVPFDILQPSILALIQAYLDTFPTILEQRNDFLLRTVQFAGLALLHKIDEK
                     IKQHRYFDNSGICTFQIARSLLTKPQESVMTVFGVSETDLIKPFVKLTKFSQAQKEVNL
                     LRLHNNKARLRGC"
     misc_feature    complement(22530..22543)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     misc_feature    complement(22824..22837)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.48"
                     /tool="antismash"
     misc_feature    22932..22946
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.21"
                     /tool="antismash"
     gene            complement(23057..23266)
                     /locus_tag="HC643_RS11410"
                     /old_locus_tag="DA73_0400011410"
     CDS             complement(23057..23266)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS11410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400011410"
                     /product="hypothetical protein"
                     /protein_id="WP_167844661.1"
                     /transl_table=11
                     /translation="MSKISSSGSRLQREYSVCNAAIQSNDKGLLLPLPCYEIRPGFGFM
                     VKNLTKTFLPIIAIHVCFLLLVLQ"
     gene            23256..23681
                     /locus_tag="HC643_RS11415"
                     /old_locus_tag="DA73_0400011415"
     CDS             23256..23681
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012472.4"
                     /locus_tag="HC643_RS11415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011415"
                     /product="aldo/keto reductase"
                     /protein_id="WP_237266070.1"
                     /transl_table=11
                     /translation="MLDTVRELGIGFVAYSPLGRGFLSGAITSPDDFAEDDYRLMSPRF
                     QGENFYKNLELVNQVKAIAAEKGATPSQLALAWLLAQGNDIVPIPGTKRRRYLEENVGA
                     TEITLTPNDLRRIEEVAPKGFAAGDRYPVQHMSTLNL"
     misc_feature    complement(23978..23991)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.26"
                     /tool="antismash"
     gene            24388..24897
                     /locus_tag="HC643_RS11420"
                     /old_locus_tag="DA73_0400011420"
     CDS             24388..24897
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410399.1"
                     /locus_tag="HC643_RS11420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011420"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_038075226.1"
                     /transl_table=11
                     /translation="MNKSNSQKLTNWLVTAVFLVLAVTFSLFDQPSASAQTQTPITTTQ
                     STPAPITSVAANIRHLLETNECVGCNLIGATLKDANLQAANLENANLQNADLERANLQG
                     TNLQGANLQGADLGKANIIGANLASANLFDADLEKANLTNANILGANLQGADLEDVVRP
                     QGFAIQ"
     gene            complement(24978..25691)
                     /locus_tag="HC643_RS11425"
                     /old_locus_tag="DA73_0400011425"
     CDS             complement(24978..25691)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747923.1"
                     /locus_tag="HC643_RS11425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011425"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_038075229.1"
                     /transl_table=11
                     /translation="MNAKPAKKYALVTGGNKGIGFAICKGLLNAGFEVILAARSLSKAR
                     DAAEKLSSPSNVRPVVLEVTDDSSIHDAVRELSQQINHLDVLVNNAAIYPDEGVNILNI
                     SRELLDVALNTNTLGPISIVQAFLPLLEKASSARIINVSSGYGEIGGLSAQVPSYCLSK
                     LALNGATIMLAEALRPKRIAVYAMCPGWVRTDMGGASAPRSPEEGADTALWLATEASLS
                     DSGKYFRDRQEISYC"
     misc_feature    25791..25806
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.11"
                     /tool="antismash"
     gene            26035..26196
                     /locus_tag="HC643_RS11430"
                     /old_locus_tag="DA73_0400011430"
     CDS             26035..26196
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS11430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400011430"
                     /product="hypothetical protein"
                     /protein_id="WP_153021456.1"
                     /transl_table=11
                     /translation="MLEIRVLYSVMETSEAVASSFTRVDAFEQIRVNISSMAQKSKSWE
                     VTVSKLHS"
     misc_feature    complement(26210..26223)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.57"
                     /tool="antismash"
     gene            26467..27066
                     /locus_tag="HC643_RS11435"
                     /old_locus_tag="DA73_0400011435"
     CDS             26467..27066
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747922.1"
                     /locus_tag="HC643_RS11435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011435"
                     /product="GUN4 domain-containing protein"
                     /protein_id="WP_038075232.1"
                     /transl_table=11
                     /translation="MSNEVHESEVTARLTAIELQLKQFNQLLSNLSDRIAKSEDNFLLI
                     ADIHKYKKLQELLIVGDLREADWETIRVIQAITKEPELGDITPDDMRQFPCDELRVIDN
                     LWTKYSEGRFGFSVQIKIYQSVGGSLESTINQDSKAIERFGERVGWREDNRWKKCDDLD
                     YTLAAPIGCHPSRWWNSPFGSKMTNYFFNRLLVCSI"
     gene            27255..28484
                     /locus_tag="HC643_RS11440"
                     /old_locus_tag="DA73_0400011440"
     CDS             27255..28484
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408671.1"
                     /locus_tag="HC643_RS11440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011440"
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_038075236.1"
                     /transl_table=11
                     /translation="MSKKSDTLLACKVLFPVLLVSALTSACSQDKPKATASEPQPIPVK
                     LQSLQSTTLQDVSEFVGRLEAQQRVSLRPEIEGRIESIPVASGDRVEQGTPIVILRPDR
                     TQPELLSAVARVNSAKSAYLTARSQLKAAEAQQVRDAADVELQKVEFQRTQKLVTEGAQ
                     AQQQLDIARKNLNTALATLRATAEQVGAAKASVKQAEANVRQYEADTASARVSLQFKQV
                     LAPITGEVGDFPVKVGDVVSVGQSLTTITQNDNLFLRISIPSNRSSEIRRGLPVELVDA
                     KTRKPLSTGTINFISPEVDTGAQAILTKARFSNSGNNLREGQFVRARVIWNKRSGVLIP
                     TVAVSNLGAQSFVFVAQTTGSKQTVRRQPVQLGAIQGQSYQVINGVKPGDQIAVTQILT
                     LRDGTPIKAN"
     gene            28563..31826
                     /locus_tag="HC643_RS11445"
                     /old_locus_tag="DA73_0400011445"
     CDS             28563..31826
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747920.1"
                     /locus_tag="HC643_RS11445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011445"
                     /product="efflux RND transporter permease subunit"
                     /protein_id="WP_050045684.1"
                     /transl_table=11
                     /translation="MSIADIFIRRPVFTTVCTVIILLVGGICIPLLPLDKLPEMALKQV
                     TVTANYLGTDAKTAEENVTTVLEREINGTERVVYMSSQTTNDGNATINVSFPTEMDRNT
                     AQVLVQNNVAIAEPNLPEEVNRIGVTTQKQSPTITLAYAFYSEKDQNGKFIYDNIFLSN
                     YVDRQIFDEIKRIQGVGSIRIVGERKYAMRIWLDPEALAARNLTSQDVIGAITEQNIQV
                     GAGRIGQQPTSTEQQYEIALRANGRFTTPAEAEDIVVKVGQDGTLIRLKDVGRAEVGAE
                     NYNATTLFDGSPAVILLAYQLPGTNAWNTANAIKAKMAELQTNFPPGLKATIGLDNTLF
                     VASSLDEAFKTLVEAIALVFLVIFIFLQDWRTTIIPALAIPVSLIGAMAIAYVLGFTLN
                     QLTIFGIILATGLVVDDGIVVVEAIAAKLEQGMKPLQAALDAMKELTGAIIATSVVLMA
                     VFIPVTFFPGTTGIVYKQFALVIAFSIAISTFNALSFSPSMSAIIMRRQQEVHGPLGVF
                     FRWFNRVFDWFKGGYVKIVEFLIRVRWLVIPVFLAGLFATGWIYQTTPQGFIPEEDQGY
                     FFTIVEAPPGVSLNYSVDLVKKITEEVVLPLPEVEHVVGNAGFGFEGNASNKTLFFVKL
                     KDWQERHGAEHSIFGVLRKINKGLREKIPGAIAIAVNAPPVDGLGSTGGLEMYIQNKQA
                     LPMEALIDNTQKVIAAAQKRPELGGVFTQFTFNSPMMQISIDRNQAKAQNVRVSDIFST
                     MQTYLGASYVNQYVLGGRLYRVYAQAEGTIRSNPDDVSRLYVRSQDGNLIQLSTLVQME
                     RLTYPPVVTHFNVYPSIKIQASPAPGYSTGQAIQAMEEVANQVLQPGFGFAWTGTAFQE
                     RSSSGAAPIIFGLAFVMVFLVLAAQYESYVDPTIIMITVPLAILGALGAIVFRANIFQQ
                     GGVWPTLNNNMYVQVALVMLIGLASKNAILIVEFANQSAELGMNYTRAAIRACEERLRP
                     ILMTAFAGLVGFWPLVIASGAGAMSRWALGTALFGGYLISTVLSLFLVPVLYVVIKNLE
                     DRFLKPGKPGKPTSPSQPSDTPQPQEQVLPAFRGYSTEE"
     gene            32493..32726
                     /locus_tag="HC643_RS11450"
                     /old_locus_tag="DA73_0400011450"
     CDS             32493..32726
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747918.1"
                     /locus_tag="HC643_RS11450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011450"
                     /product="hypothetical protein"
                     /protein_id="WP_038075241.1"
                     /transl_table=11
                     /translation="MNIKLIIFSGLITAGIGSVIGLAAAQIGQSNFNELKFEGQYYKDL
                     HNRYALIGASVGLVVGMAQECVREMKSQREEE"
     gene            32754..32918
                     /locus_tag="HC643_RS11455"
                     /old_locus_tag="DA73_0400011455"
     CDS             32754..32918
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747917.1"
                     /locus_tag="HC643_RS11455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011455"
                     /product="hypothetical protein"
                     /protein_id="WP_167844662.1"
                     /transl_table=11
                     /translation="MKIKHSLICLLIIGTTVLTAANWHLGMMGMTTFLLAYFSKGLRRR
                     SHINGRLAK"
     gene            complement(32896..33846)
                     /locus_tag="HC643_RS11460"
                     /old_locus_tag="DA73_0400011460"
     CDS             complement(32896..33846)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017318813.1"
                     /locus_tag="HC643_RS11460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011460"
                     /product="glutathione S-transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_038075243.1"
                     /sec_met_domain="GST_C (E-value: 2.3e-07, bitscore: 29.7,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLVNGVWHSDFQPLEGERIQTGSFREFISADGSSGFKAERDRY
                     HLYVSFACPFAHRTILARQLKQLNSVISMSVLSPDWGDPSGWTFGDWSHTTADTVNGCD
                     YLYQVYVKAKSNFTGRVTVPVLWDKQTGTIVNNESADILRMLVTEFDAFGNASLNLYPQ
                     ELRAEIDDINAFVSDRINIGVYKVGFASSQLDYNTAIAQLFDALDILETRLSGQQYLVG
                     HSLTEADIRLFVTLVRFDVAYYGALNCNLRRLTDYPNLWNYTRHIYHLPNVSDTVKFDH
                     IKRHYYDTYEGLINRRIIPIGPILNWDIPTLQVCH"
     gene            complement(33898..34803)
                     /locus_tag="HC643_RS11465"
                     /old_locus_tag="DA73_0400011465"
     CDS             complement(33898..34803)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="HC643_RS11465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011465"
                     /product="DMT family transporter"
                     /protein_id="WP_050045685.1"
                     /transl_table=11
                     /translation="MQKQNPFGLFAVVGASTFWALAANVASSLFEGGVSPFELAGVSAI
                     LATIGLMALNLLQKHPILRVPSLSQIALSALFVMFVGADYLAIAKLPVAIAIVLIFMAP
                     GFVVLWNALLSRRVPSAKVLIALALSFLGVVLVSGVVGGDLSQVNWFGIAIGLTTAILF
                     AAYTLLSEKIGAQGTPVNALLQTFSIASLIWFGFLLTQGLTPHLLEVINAPKILYMGIM
                     GTLLPYLLFLWGVRHVQAERAAIVASIEPFIAGIIAWIWFGQYLTLLQITGGILIVVAI
                     SSLQINNQATLKKNRLNYEG"
     gene            34930..35388
                     /locus_tag="HC643_RS11470"
                     /old_locus_tag="DA73_0400011470"
     CDS             34930..35388
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /locus_tag="HC643_RS11470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011470"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_050045686.1"
                     /transl_table=11
                     /translation="MAKQRLDEMRNSTWRLFLTVQIQAIEKIQEKLSAAKLPPLEWYDV
                     LWELKKVPEGRLRLSELAERVLLSRSHLTRLLDRLEKSELLERQPCPSDRRGTFAVLTE
                     AGAAMQEKMWAIYSEGIAEYFGDRLSDEEVKVMQQALKKVLGENSTQK"
     gene            complement(35689..36591)
                     /locus_tag="HC643_RS11475"
                     /old_locus_tag="DA73_0400011475"
     CDS             complement(35689..36591)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (42-285). E-value:
                     3.2e-24. Score: 77.8. Matches aSDomain:
                     nrpspksdomains_HC643_RS11475_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="HC643_RS11475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011475"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_162002222.1"
                     /sec_met_domain="PF00561 (E-value: 3e-18, bitscore: 65.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.6e-22, bitscore:
                     79.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTQSVEMAQAAYLDRCAPGYRTRRVHWSGGTTQVIELGEGTPLL
                     LVHGGMGEAFQWGSILSALAKSHRVLAVDRPGHGLADAFDYRGVDILAHACRFLGDILD
                     TEGLPAVPIVASSMGSLWSVAFALSHPERVPRLVLVGAPAGIQRSQPLLMRLGTLPILK
                     TIVRSQMQKPTRESTRAFWAQLMVAHPERLDDDFLDVSTASQARNVTNWFTLIDSTVDV
                     RGMKQKLVLGDRWKQLSVPTTLIWGEKDVWCQPEVGEAVAASNPQLRVVRIPDAGHAPW
                     FDRPDRVVNAILEALAALR"
     aSDomain        complement(35737..36465)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS11475_Abhydrolase_1.1"
                     /evalue="3.20E-24"
                     /label="HC643_RS11475_Abhydrolase_1.1"
                     /locus_tag="HC643_RS11475"
                     /protein_end="285"
                     /protein_start="42"
                     /score="77.8"
                     /tool="antismash"
                     /translation="PLLLVHGGMGEAFQWGSILSALAKSHRVLAVDRPGHGLADAFDYR
                     GVDILAHACRFLGDILDTEGLPAVPIVASSMGSLWSVAFALSHPERVPRLVLVGAPAGI
                     QRSQPLLMRLGTLPILKTIVRSQMQKPTRESTRAFWAQLMVAHPERLDDDFLDVSTASQ
                     ARNVTNWFTLIDSTVDVRGMKQKLVLGDRWKQLSVPTTLIWGEKDVWCQPEVGEAVAAS
                     NPQLRVVRIPDAGHAPWFDRP"
     gene            complement(36588..36710)
                     /locus_tag="HC643_RS42085"
     CDS             complement(36588..36710)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS42085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_272899736.1"
                     /transl_table=11
                     /translation="MLRSTIKYKVEWIGALFIEVPTNDRGNVHRGGKTVGCNLT"
     misc_feature    complement(36846..36861)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.07"
                     /tool="antismash"
     gene            36855..37403
                     /locus_tag="HC643_RS11480"
                     /old_locus_tag="DA73_0400011480"
     CDS             36855..37403
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS11480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400011480"
                     /product="hypothetical protein"
                     /protein_id="WP_162002223.1"
                     /transl_table=11
                     /translation="MLNNELETLGWLAIAQLAIIIIFGLLFSTIAKFKYQNSSASHRVF
                     KQGDYTSCFIEDPQVIFQTIPKCYYFVVVNYQPNDQVIQESFYTILGDVTSINYSDGKW
                     VATKSNLYSNMLLVALPLIGFILILSSNLVTQSVLDSVITRQSDITEQLTNYGTILFGS
                     VFLSAPIKMIFDFFNHFKI"
     gene            37453..38052
                     /locus_tag="HC643_RS11485"
                     /old_locus_tag="DA73_0400011485"
     CDS             37453..38052
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408535.1"
                     /locus_tag="HC643_RS11485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011485"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_038075256.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.9e-38, bitscore:
                     129.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIGLILLAAGASTRMGTPKQLLQYQQHSLIRHMVEVALASVCN
                     PVIVVLGAYAECIRPEVELSNVRIVENDRWAEGMSTSIRCGMEALNEIKPGVEAVVLML
                     CDQPFVSTQIVNQLVNIFQETDGQIIASEYGGVRGVPALFKRNLFAELLTLNGVAGARQ
                     VIKQNAEKVVSFSFPEGIFDLDTRNDYEQFKNAISI"
     gene            38170..42081
                     /gene="cobN"
                     /locus_tag="HC643_RS11490"
                     /old_locus_tag="DA73_0400011490"
     CDS             38170..42081
                     /EC_number="6.6.1.2"
                     /GO_function="GO:0051116 - cobaltochelatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1263: cobaltochelatase subunit CobN"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017749712.1"
                     /locus_tag="HC643_RS11490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400011490"
                     /product="cobaltochelatase subunit CobN"
                     /protein_id="WP_038075260.1"
                     /transl_table=11
                     /translation="MHRLATTPGGWNPSAEGVMAIEQQPAPIVLITAADTDIQTLSVAV
                     TQLPSEFLQLRVVNLLQLQQQLTIDMYAEDVLSAAEVIILRLLGGRAYWSYGLEVVEQT
                     VKQTGAKLIVLPGDERPDLNLISCSNVSLVDANQIWQYFNEGGTENYLNSLKFIATTFL
                     GCTYTFNLPQPVPRVGTYSPSDRIIYTQVENNFIPVRKPDSQIGVIGIIFYRSHYLAGN
                     TSVIDALCQALAQRNLTAIPIFVSSLREPDVQAELLKYCSQKIDLLLNTTSFALAKLEA
                     ETPQVELWEQLDIPVLQVILSGSSREHWESGSSGLTPRDIAMNVALPEVDGRIITRAVS
                     FKAVKTPSPLLQTDVVSYEPVASRIEFVADLAANWVKLRHTPPQNRKIALILANYPNRD
                     GRLANGVGLDTPASCIEILKALQLAGYYVDNIPNTGEELIQLLTTGVTNDLEGYPFREV
                     RQSLSLQKYLEHLYSLPEAVQEGLKNRWGFPEETDSLPISGIQLGNIFVGIQPSRGYDR
                     DPSLNYHAPDLEPPHSYLAFYHWLVESFGANAIVHVGKHGNLEWLPGKSVALSENCYPE
                     AVLGAIPHLYPFIVNDPGEGSQAKRRSQATIIDHLTPPMTRAELYGNLYSLEGLIDEYY
                     EAQSLEPSRLPAISDRITQLIEREHLHQDLGIDISRFDKSTLSSFLNAADGYLCELKEA
                     QIRDGLHIFGQCPSGKQLRDLIVAIARNPGVGRLGLTRAIAIDWQLDFDPLTVDFSQAF
                     EINFPTLTLPETSFYREVGTATSDLTPPQSPSDGEAGASDGSSLYKEGLRELSERYQKL
                     KNCRIIGDVIQILEDCASDLVTYIIENEEIPQSGKTTTQELRWIQNFLLKALRQTEKEI
                     INLLRGLDGKYVASGASGAPTRGRPEVLPTGRNFYSVDIRAIPTETAWDVGSQAAEILI
                     ERYTQEHGEYPQTLGLSVWGTSTMRTGGDDIAEALALLGVKPVWDGISRRVVDFEILPP
                     SILGRPRVDVTLRVSGFFRDAFPNLMDLFDSAVTAVAHLDEPEDINPLAAKVKTETEFW
                     QTEGLTAEQAKARSLYRIFGSKPSAYGAGLQGLIESQNWTNEDDLARAYINWSAYAYTR
                     KAEGKFVPEAFTQRLHNMQIVLQNQDNREHDLLDSDDYYQFQGGLTVAVRSVSAKLPVT
                     YFGDNSRPQQPKIRKLTEEITRVYRSRVVNPKWIAGAMRHGYKGAFEMAATLDYLFAFD
                     ATTNCVADFMYQGIAEAYLFDETVQQFIQQNNPWVLRDMAERLLEAHQRGLWENVSGET
                     LETLRSLVHEAEGIIESQF"
     misc_feature    complement(42251..42262)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
ORIGIN
        1 ttgcagttat gattttcaca gggaatttat ttgcatcttt caatctttta gctatccttt
       61 tcgcctctgc tttgtttgct gcagggtatc agttatttaa aactggtaaa gttttgaatt
      121 atagtttgca gtctgttagg gaattagtca aacgctaaaa ggataaaaaa cttctccata
      181 taaattccct ctttttctgg ttctttcagt ttcttgttcc caggtagaac ctgggaacga
      241 gagtcaagcc tgagtacagg agtgtctgtt taaatttggt agtcccacat tgaaattttg
      301 ccacaaaatt gatttgcagg tacagcagcc aacattttct taggataggg aagattcagg
      361 ttattcatga gttcaataaa ctgcttgcgg ctgcgtccgg caaaacgcgg gttccaagat
      421 ttttcttctc cgatggtaga tactgttcgt ccttgatagt catgaccggg atacacgaaa
      481 gtctcttccg gtaaggcaaa cagcttttga gttacaacat catacaacaa tcccgcatca
      541 ccgttttgaa agtcggtacg accgcaacct cggataaaca aagcatctcc acttaacaaa
      601 tgagttccat tcacgagata tgccatatga ctatctgtgt gtcccggtgt tgcgatcgct
      661 tgaattctca cactccccaa ttccagtatc gccctatctg caatatagct gtctgcaccg
      721 atggtcgcag ctttttcagg gacaatactc aaacaacccg tcaattctct caatttatct
      781 gacccggtta tgtggtctgc atgaatgtgg gtctccagac agtaacgtaa agtcaatccc
      841 aattctcgca agatttgaag gtcgcgttcg acttgttcca acacggaatc tatcaggata
      901 gcttctttcg tttctgggtc ggcaatgagg taagtataag tacttgactc tttatcaaac
      961 aattggcgaa atagcataac aggtttcggc aacttgctta cttcaatagc aggataaagt
     1021 ttggaatcga gagatttcag taactcctga gctaaagaaa ctgcctgaac tcgaatttct
     1081 ggaacagcag ttgtttccca aagatttccc ttacggggtg ttcctaacgt atacaaaagt
     1141 tcggaaacat tgccatcagc atcaatgaga gcaccgttag cagcagtatc aataccgata
     1201 gacagggtgc tcgaacggaa tagcctttgt tcttgaaggc tcgaaagcaa cggatgctgc
     1261 aatctgcggt agttgcagtt tgaaccggta cagttcacta ttctgcttac ctgtagaaca
     1321 atatctgcac ttgttccccg ttcgcgaatg gttacattca ctcccttctc aaactcttgg
     1381 caagtttgaa tccgacctcc gtagtggcgt aattgaccgg actgaacggc tgtatctaaa
     1441 acttctgcaa tttcttcagc aatccgatgg cggtgaactt cccagtaagc tttcacgtgg
     1501 cggagaaacc ttttctgttc tttaaatgga agtgcttgcc agagttcttg agtgaccgga
     1561 cggagagcat caatgactcc acgccagtct tgtcctcgat cgctcgcgac ttttacttcc
     1621 tgacgtacca agtggaacag ccctcttgca gtttttggag cagtttccaa attgagaaat
     1681 gctgcgtaag gagttgttgg tttgtgatga cagggcatta agccatggcg ggagactgcg
     1741 tgaatctgtc ctttaaatcc ttgttggtgc agcgcaacaa ctgcatctgc catagtcagc
     1801 ccagttccca ctagcaaaat tgaatcttct gggctgagat ttgcgatcgc atcttcagcc
     1861 caagcatctt taacataggg attggggtta cccaaagcag caattggttc gggtaaagaa
     1921 gcaggaaaat tacccaaagc aagcacagcc ttttgtacct gcaaacgcct gccattattc
     1981 aagtacactc gaacgctata agttgttgta tcaatataga tagcttcacc aacaatcctt
     2041 tcaaactcga ccccagcttg agcctttgcc tgtgcttctt gcaaaattgc ttggatataa
     2101 cttccataaa cagtacgcgg tacaaatgtc gatgcagtga cttgttcgta cccatttgcg
     2161 tgtagccatt tcaagaaatg atctgattca tctggaaatg cactcatctt acctgcagga
     2221 acgttcagca aatgacaatc aactcgcgta ccatatgcga cccctttacc tatttcacaa
     2281 ttgcgttcaa ttaattttat agaaatcggt attgttgcat tacgcaaaag attagcagcc
     2341 acaagagaac cacttaaacc gcctccaata atagctattg tttgtggaga aacactttga
     2401 tttaaaatag acttatacat aggaaaaact aaatttattt ggtgtatatc tacaaaattt
     2461 agtccatccc ttccgtaaat gtccatgctt ttctcctggg tataagtaca aatcaaattt
     2521 aaaccccact taaacaaccg aaaaactcgg aatttccatt gagtctttaa tatgttgaaa
     2581 tcgcatcatc tcaaacccag ataaaataag tatttaagaa tttaatgtgc cttcttgtcc
     2641 aactaatccg atacgaatag tgttgtttta aaattaccta ttatgagtca tttttttacg
     2701 gaaatttttc ttaactcatt gttatgattt cctgacaaaa ctagaaaatc tgctgctctc
     2761 tagggactcg cagtcgttaa aaaaattact tttgaagcgc agaggtacag agaacacaga
     2821 ggaaaaatga tttactcgcc aaccatgatt agatagcaac tcttcttctc ttcatttctt
     2881 cgtttcttct aaggagtgag aaaattttat aattccaata acgattctat ttaatttgca
     2941 ggaaatctcc caatgaatgc acattgctct cattcataga attctgagac tatacaaaca
     3001 aagttcctcc cgtgggaaac tcccttacaa ggctcgattc actacctgcg cggattcatt
     3061 acaacacaag atctgaaacc cacttaggtg agttttgcgt gtatagcctc aattacgtac
     3121 cttctcaaat attctctaac aatatgacaa atcaaacact tggactcgaa aaaaatctgt
     3181 atgagtactt attatcagtc tccgtacaag aaccagaaat tttaacacaa ctgagacaag
     3241 aaacagccca gcacccaatg agccaaatgc aaattgctcc agaacaggga cagtttctcg
     3301 ctttactggt tcagttgatg aatgcaaaaa aaacattaga tataggggta tttactgggt
     3361 atagttccct agttgttgct ctagcattac caccagaagg taaagtcgtg gcttgtgatg
     3421 tgagtgaaga gtatacagcg atcgcacgtc gttattggca gcaagcgggt gtggcaaata
     3481 aaatcgagct acatatagcc ccagccatag agacattaga tcgcttgcgg gcgcagggag
     3541 aaacttttga ttttgccttc attgacgcag acaaaagtaa ctatgacaat tactacgagc
     3601 aagctttaca gttagtgcgt cccggtgggt taattgccat tgataatgtc ttgtggtcgg
     3661 gaagagttgc agatcctcaa gtacaagata acagaacaaa ttatatgcgt acttttaatg
     3721 agaaattgta tcgagattca agagtcacaa ttagtttagt accgattgct gatggtttaa
     3781 ctttagcact gaaaaaaggc taatggctaa tagctaatgg ctgatggttg atggttgacg
     3841 gctaatgatt aatatgcaga tgacatacgt gaaatacaat ttacaaagct gcattaaaac
     3901 cctgctgttc ggtgagtttc ccgatgcgaa aaatacacag gtggggaata aaaacaatta
     3961 gctattagct attagctatt agccattagc aattagccat taacactcct tctatttgcc
     4021 aattctattt gtcgctgctt ttccatctga cgttcttttt tcccctcaga aagggtttca
     4081 aaacagtgag gacaggaaat acctttttcg tattgaggag aagttttgtc tgcttcagag
     4141 atgggatgtc cgcaactcgc acacaaatcg taagttcctg gttctaaagc gtgacgaaca
     4201 gcgatacgtt cgtcaaaaac aaaacattcg ccttcccaca aactttcaga ttctgggact
     4261 tcctctaagt atttcagaat tccgcctttt aagtgataaa cttctttaaa tccctgagaa
     4321 atcataaagg aagaggcttt ttcgcaacga attccacccg tacaaaacaa agccactttt
     4381 ttgtgttgct tgggatctag ctgatgaaaa acatattctg gaaattcgcg gaatgacttt
     4441 gtgttgggat tttgtgcttt ttggaaagta ccaatgctga cctcgtagtc attgcgcgtg
     4501 tctatcactg tgacttctgg atcgttgagg agagtattcc aatctttagg atcgacataa
     4561 gtaccaactt gttcgtttgg attgacttct gataacccga tggtgacaat ttctttcttc
     4621 agtcgcactt tcatgcgttg aaacgggggg gactctgcgt gtgattcttt atgttccaaa
     4681 tcttccaagc gaggatcgct acgcaaaaag gataacactg aatcgatcgc ttgacgagaa
     4741 cctgcgatcg taccgttaat gccttctggt gctagcagaa tcgtcccctt aatatcatgt
     4801 gcttgacaaa aagataacaa aggctgttgt ttctcagcaa aatctggcaa actcacaaat
     4861 ttataaagtg cagcaacgac taaagacatt ttttgattaa tcccctttcc gcaaaccagg
     4921 aatttaagct atgatacttt tgttggtgta aattacttac acttcctatc ttaagggggt
     4981 atagctcagt tggtagagcg cctgctttgc aagcaggatg tcaggagttc gagtctcctt
     5041 acctccatag ttagcgatcg ctaaacaatt attgtcaagc atataatcta gtcatcgtcg
     5101 tcttcgtatt ctgcccatga gtttggagtc tcagagactg ctactttgag atgtacgccg
     5161 ggagggactc tttttttggt ttcatcgtaa atatacttgg caatcatctc agcagttgtt
     5221 tcatattctg ggggtatgac ttcgttaagt acgcagtggt caagccctcc ttttttcaca
     5281 tcctgtttag cccagcgtaa ggttctaaaa tcagccacca taacttcatg gggacagtat
     5341 tgcgaggagt gcagttttga tgaagttgct tcaattttta ctttgtaagt atgaccgtgc
     5401 aatcgaccgc acggtccatc gtagtctcgt atgtaatggg cgctatcaaa tgtaaattca
     5461 gtgaccaatt tccactttgg cattcttgta tcctttaatc attgccactg ggtaatcggg
     5521 atttactgga ttcggtatca actgttgatt tttacaatct gcaagtaaat ccaatttttc
     5581 aaaaaattac ttgaccaatt aatagtttag ttcccataaa aaaagcttta tcaactgtta
     5641 tctttacctc acatttaata attattggtc tagttgctac aatagctttt tgatttccat
     5701 cattcgtatt gtgcaactct attattacac atcacaaaaa aggtaatctg aattcaccca
     5761 accttccaaa ccactcacct tagtgttggg accattaacc acacggacgt aaacccaagg
     5821 ttccgctccc cacctcagcc atttaacaac gttgccatta tttaaaccag cttttgattt
     5881 accattgggt gtagatcgta aagctaactg tccctgtgta atatttatga ctttacagga
     5941 ttctggtgaa gatgctgttt tctcatcaca aatcaagtaa ttggaattaa cccaaccttc
     6001 taaaccgttc actttaatat tgggaccccg aagtacccga acgtaaaccc aaggctcgct
     6061 tccttgcctt aataattgta cgctattgtt attatttaga cctgctcttg acttgccatt
     6121 aggttgagag cgtaaggcta gttgacctgt ttgaatatta gttaccgtgc aactggtttg
     6181 ttgagcaaga attttttgat ttcccatacc agcaaaggca gtaggaacaa agttaaaact
     6241 agataaagat aaggatatta gaaatatctt taacagagag gtttggtttt tcatcggtca
     6301 tcaatctcca catctcggac aagcaccgat cgttaagtca agcgccatgc ctccgagaaa
     6361 attaacacct ctttaaacta acttcactat gattcccttg tactctgaga atctacggaa
     6421 atataataat gtagatgggc agtacaggac tcgaacctgt gacatcctgc ttgtaaggca
     6481 ggcgctctac caactgagct aaccgcccgt cgtgttttga ctcacaagaa ctaatgttag
     6541 cacagaaatt ttgaaaacgc gatagtattt ttgagaaaat tttttccaca tattcctatg
     6601 ccctctggtc ggactcacga tcgcattact ctatgggctt tgccacttgt gacaggggtg
     6661 actttctggc aaaccaaaag cggtaaccta acactactag tagcaggagg gtttctgttt
     6721 ggcggactga tgttcggtcc cgatttagat atttactcgc gccactacca gcgctgggga
     6781 tttttgcgtt ttatttggtt accttatcaa aaaagtttgc gtcataggtc attcttatcc
     6841 cacggtccca ttattggtac aacactgcga gttatctatc tcagcacctt ggtagctatc
     6901 ttaggaattt tggttatagt agttggcgaa aagctgtgga atctgcagct agattggcaa
     6961 atattgcata agaatacagc aaacacgcta ttcaattact ccagagaact tctagcccta
     7021 ttctttgggc tagaaatagg tgctatgagt cattctttaa gcgattggag tggttcggca
     7081 tacaagcgag tgaaaaagca aggagtcagt ggattgctac ctcgtgggaa aatgaagaaa
     7141 agtaaagtga aaaggggtac gaggagacaa gggggagcag gggataaggg gacacggggg
     7201 actaggaaga aagggagcag ggaagcaggg gagcagggga gcagagaagc aaagaagtag
     7261 aggagcctac cttatcctcg gtatccttca atccaaaatc taaaatccaa aatttgtata
     7321 atcattaacc aattatgaaa aattctgaca tattagcggc tttgcaagaa ttaattgacg
     7381 tggtggcaaa attgcgatcg cctgaaggag gttgtccttg ggatttggaa caaactcccc
     7441 agacactgac accctatgta atagaagaag cgtatgaagt tgtagatgct attaatagtg
     7501 gagataaaaa cgcgatcgct gaagaattgg gtgacttact tttacaagtg gttttgcaag
     7561 ctcaaattgc cagcgaatac caacaatttt ctctaaagga aattgctgaa ggtatttcac
     7621 aaaaacttat ccgccgtcac cctcatgttt ttggtgatat ttcggtgcaa aacgtggatg
     7681 aggtgcggca aaactgggaa aaaatcaaag ctgaagaaaa aggaaaacct gctcctgaaa
     7741 gccaaaaact cagttacaaa cttcaaggat atacacgcaa gctacccccg ttaatggcta
     7801 ctatgaagat ttctcgcaaa gcagctgctg tggggtttga gtgggaaaac cttgatggag
     7861 tgtgggataa atttaatgag gaattagcag aattcaaaga agctttagcc cacgaaacac
     7921 cagaaagaca gcaagaggaa ttaggcgatt tgctgttttc tatcgtccaa cttgctcgct
     7981 ggaataatct cgatcctagc gaagctttgc aagggacaaa cagaaaattt attcagcgct
     8041 tagaacaaat ggagggattt gccaatcgtc ctctctcgga ttacacccta gaggaattag
     8101 aagctttttg gcaacaggct aaagcagtcg agcggatgga gactgggggt tagggactgg
     8161 ggacagggga gacaaggaag aaaattctcc cttgtcccca attatatcaa atccgtttat
     8221 agcggaatta tttctctttc ctctctctct gcgctctctg cgtctctgcg gttttttaat
     8281 cgatgctacc ggatttgata ttacaactta attgtcaccg tcttaacctc agtgtattgc
     8341 tgcaaaccgt attcaccgag ttcgcgacca ataccggact gcttaaatcc accaaaaggt
     8401 gcagcagcat caaaaacgtc gtagcagttt acccaaacag tacccgcacg aacgttgtta
     8461 gctatggcgt gtgctttggt aatgtccttg gtccatacag cagctgctaa cccatacatg
     8521 gtgttattag ctcgttgaat aacttcatca atatctttga atttgatgat gctcatgacc
     8581 ggaccaaaga tttcatctcg agcaatttcc atgcggtctt gcacatcagc aaagattgtt
     8641 ggggcgataa agtaaccttt gtcacccact tggttcccac cacatagcat tcgagcacct
     8701 tctcgcattc ccgcttctat gtaatgcatc actttgttga actgttcttt atctacctgc
     8761 ggaccttgtt tggtattgag gtcgaaggga ttaccgacag tgcgctgttt tgcgcgttcg
     8821 acactcttgg ctacgaactc gtcataacat ttttcttcaa caaagagtcg cgaccctgca
     8881 acacagcact gtccttggtt aaagaataga gcattatgag cgccttctat agcctcatcc
     8941 atgtcagcat cggcaaaaac tatattgggg cttttaccgc cgagttccag agtcactcgt
     9001 ttgaggttac tctttgcggc tgcttccatc accaaatgcc ctacttcagt cgagccagta
     9061 aaggcaactt tgtcaatatc catatggtgg gaaattgcag cacctgcagt tggaccgtat
     9121 cccgaaagaa tattcacaac accagggggg aaaccagctt caatcatgag ttcgcccagt
     9181 cgcaatgctg acagtggtgt ttgttcggct gttttcataa ccactgtatt gccggttgcc
     9241 aaagcgggtc ctaatttcca agcctgcatg aggagtggaa agttccaagg aataatctga
     9301 cctaccacac cgactggctc gtgacgagtg tagcaaaagt aaggaccgtt gatggggatg
     9361 gttttaccct ggactttatc agcccaacct gcaaagtaac gatagcaggc gatgactaat
     9421 ggcaggtcag cattcatcga ctctgaaata ggcttaccat tgtctaatgt ctccaactgc
     9481 gccagctctt ctttgttctg ctcgattaag tcagccagtt tgtaaagtaa ctcgccgcga
     9541 cgagttgcgg acattgtacg ccattctccc ttgttgaaag cagcacgagc cgcatgcact
     9601 gctttatcta catctgctgc atctgcctct gctacactgc aaatcacgtc acccgtagca
     9661 gggttaattg tttcaaaacg cttaccgcta atactttcta cccattcgtt attaatcagc
     9721 agattggttg gaccgatttt gacctggttg tctagtttga gtgctgtaac catcgggtcc
     9781 tcctataagc taagctttta ttagagatgt gtttaaatct accttatatg ttgcttggta
     9841 cgtggcgtac caggtggctt tctttatgta attttatggt ttgctttaca tatggaaaac
     9901 ataattgcag ttgctcaaaa aacaagacgg gctgcactca aactagcagt gctttcaaca
     9961 gaggcaaaaa atcaagcaat agaggcgatc gcacaagctt tagaatcggc aaaagatgag
    10021 attttgcaag caaatcttgc tgattgtgaa acatctattg ctgagggaat tgctgagcct
    10081 ctctacaaac gtctcaagtt agacgaacac aaattaagag atgcgatcgc gggtgttaga
    10141 gatgtcggta aattagccga tccggtgggt accgtacaaa ttcaccgcga aatcgatacg
    10201 ggtttaatcc tcaagcgatt aacttgtcct ttgggagtcc tagggatcat ttttgaagca
    10261 cgtccggaag ctgctattca aattgtttcc ctagctatca aatcagggaa tggcgttatt
    10321 cttaaaggtg gaaaagaagc cgttcgttct tgtgaaacaa tagttaaagc aattaaacaa
    10381 ggattatctc aaactgcagt caatccagat gcagtccagt tgttaacaac aagagaagaa
    10441 attttgcaac ttttgaaatt agataaatat gtcgatttaa ttattcctag aggttctaac
    10501 tcgtttgtcc gttttgttca agataacacg cgcattcccg ttctcggtca tgctgatggg
    10561 gtttgtcatc tttatataga taaagcagcg gacctagaaa aagctgttgc tattacagta
    10621 gatgcaaaaa cgaactatcc agctgcttgt aatgcaattg aaactttact cgttcatgcc
    10681 aatattgccc caaaggtatt accacaaata agtgaagctt tgcaacacct taaggtagaa
    10741 ctaagagggg atgaacgcac gcgccaaatt ctacctaata tcttagaagc aaccgagcag
    10801 gactgggaaa cagaatataa tgctctgatt ttatcaatta agattgtaga ttccttagaa
    10861 gaagcaattg ctcatataaa cgagtatggt tccaaacaca ctgatggaat tgtttctgaa
    10921 gacgaagaag ccgctcaaac attcttagca ttggtaaatg ctgcaggagt ttaccacaac
    10981 tgttcgaccc gctttgcaga tggcttccgt tacggttttg gtgcagaggt tggaattagc
    11041 actcaacaaa tgccacctcg aggtcctgtt gggttagaag gtttggtgac ttataagtat
    11101 caaatgagcg gtaacggtca gattgcagct acttatacgg gagcaaacgc taaagccttt
    11161 acccataggg atttgctata gaagattttt gtggttacaa taataccaag tacttgttgt
    11221 tattttgtta cacagtgtaa gaagacaacc agggaaatag ggtctgagaa ctcctattga
    11281 gtttttgaaa tctacgtatg gtggataatg cccaccatat gttgcttttg tgcggcacga
    11341 tcttacctac ggtacagaaa tatttttcgc cgaacaattt caggattata ataccatttt
    11401 taattttttt taacattaag ttttaataag ccttggtgtg agtcgtcaat gcaatgagag
    11461 atgaagataa gacaaaagag cagttaattc aagaaattgc tgaactgcga caacgtgttt
    11521 caagcttaga aacattagca actcaacagc agaaagcaga aacggtattg tacgatcgcg
    11581 ctcaaaggca agttcaaaga gagcaagcac tcaatcgagt cattcaaagt atccgcaact
    11641 ccttagatat aaaaacaatt ttttccacag cagcccgtga aattgctcac ctcattcacg
    11701 ccgatcgagc agaaattgta caatatttac cagaacggca actgtggtta aacgttacag
    11761 attaccgcaa aaacctagat ttgccaagtg ctttgggatt ggagattccc gatagctata
    11821 atgaaattgc gtctcgactc aagcgattgg aagttgttgt tattgaagat gcaagcagta
    11881 attatataga cgaaatcaac cgcaattttg cggagattta ctctggagct tggttgctag
    11941 taccattgca cgttaactct tcagtttggg gtagtctcag cataatacgc tcttgccaat
    12001 cttccccgtg gcaacaggaa gacatagaat taacttgcgc tgtagccgat caggtggcga
    12061 tcgccataca gcaatcaacc ctctatgaac aagtacaaag cgaactgcga gaacgcaaac
    12121 gagcagaagc agcaatttac tttcaagcgc atttattatc agccgtagaa caaggagtca
    12181 ttgccaccga ccttgatggc aaaattattt attggaatcg ttttgcagaa actttatatg
    12241 gctggtcggc acaagaagcg atcggtcaaa atattatgga tgttgttgtg accgatactt
    12301 tacgagagca aggacttaaa attatgtccg agttacagca aggtaaaagt tggtcaggcg
    12361 aatttcccgt gcagcgtcga gatggaactc atttctgcgt actagtaact gacgccccaa
    12421 tttacgatga ccaaggagtc ttaataggag ttgttggtgt ttctactgac attagcgaac
    12481 gcaaacaaat agaagagaag atccgcgaac aagctgcgtt gctggacatt gccacagatg
    12541 ctattttagt tcgagactta aaccacaaaa ttttattttg gaacaaaagt gccgagcgtc
    12601 tttatggttg gaaagcacaa gaagctttgg gacaaaatgc tcaagttttt ttatatagag
    12661 aaataccgct acaactccaa gaagcaatca atcaagttca cacaacaggt gagtggtacg
    12721 gtgaattgaa taaagtccga aaagatggta aagacatcat tgtagaaagc cgatggacac
    12781 tcgtgcggga tgaaagcggt aatccaaaat ctatccttac tgttgacacc gacattacag
    12841 aaaagaaaca actgcaaact cagtttcttc gcgctcagcg attggaaagc cttggtacgc
    12901 ttgctagcgg tattgcccat gacctcaaca atatattgtc tcccattctc ctctccgctc
    12961 aaattctaaa aatgaaactg ggcaatgaac agcacaatca gctactggaa actttagaac
    13021 tgaatgctca acgtggtgca gatttagtca agcaagtact ttcctttgcg cgtggcgttg
    13081 aaggtcagcg tacagtatta cagatgaagc acttgatcat agaaattcag caatttgcca
    13141 aacagacatt tcctaaatct attcaattta tttgtaaaac agcgtcaaac ttgtggactg
    13201 tatatggaga tgcaacacag ctctatcaga tgttgatgaa cttagttatc aattctcggg
    13261 atgcaatgcc caaaggtggt attttagata tctcggctga caattttttc attgacgaaa
    13321 actatgccaa gatgaatctt gaggcaacag ttggacctca cattgttatc tctattagag
    13381 atacaggtac gggtatgtca cctgaaatct tggatagaat ttttgaacct tttttcacca
    13441 ccaaagccgt gggacaggga acggggctgg gtctttcaac tgtgctcggt attgtgaaaa
    13501 gtcatggtgg ttttatcaat gtttctagtt ctgttggcaa aggaacggaa tttcaggttt
    13561 ttttaaaagc cgtgatggca aatgaaatac agtcaataga aaatttgccc ctacccacgg
    13621 gtaatggaga attaattttg gttgtagatg acgaagccaa aatccgagac attaccaaaa
    13681 cagcattaga aaattacaat tataaagttc ttattgctag tgatggtatt gcagctattt
    13741 caatgtatgc ccaaaatgta tctgatattc gcgtcgtctt gttagatatg atgatgccaa
    13801 ctctggatgg catgacaacg atccaaactc tgaaaaaaat taatccgtcg gtcaaaatta
    13861 ttgcttctag cggtcttcaa gaaaatcagc taattgctga atctcttggt attcacaagt
    13921 ttttgcaaaa gccatacacg atgaagcagt tgttgcaaat aatacaaaat ttgctttgaa
    13981 ggagttaggg cgtgttttca agcgacttgt ttagcctcct gttttccagc tccccctaaa
    14041 tccatacaac gttctacaag gcgggaaacc cgccctagcc cctataccaa tgctcttaac
    14101 aaagcttgta acttaagctg cacctctgca agttccttgt caggattgga accagcaaca
    14161 ataccagcac ctgcataaag tctagcgcga tcgccatcta taagtgccga gcgaattcct
    14221 acaataaact cgcagtttcc ttcagagtcc acccaaccta atggtgctgc atacaatcct
    14281 ctttcaaagt tttcataacg gcgaatttca cgacaagcaa tctctctaga agcacctgca
    14341 acggctggtg ttggatgcaa ttgcgcgact atgcttaagg gatgaacgtt attaggaaca
    14401 atcgcattta tgggagtcca taaatgttga atgttagaca gttgtctcaa acgaggtctt
    14461 aatacttggg gtagtaaacc cagttgcgac agccgttgtg taataaaatc aatcactaga
    14521 gagtgttcgt gcctttcctt ttcactactg agcaagcgac tggcatttac tgcatcttca
    14581 gctggtgttt taccccgtgg agcagaacca gcaagcgcat cagtaattaa ttgctgcttg
    14641 tcaatgccta tcaaacgctc tggactagct cctataaagt tctgtccttt tccattactt
    14701 atagaaaaga tacaacaatt ggaatgcagc tgtcgtagat tatttaaaga ctgtagtaag
    14761 ttaaatcgaa tactggctct aacatctagt gcatctgcta ataccacctt tctcagacgc
    14821 tttgattgaa tactttctaa agctcccgat accgaacgct taaactgctc tggattagcg
    14881 acatattgtt gactcaattt tggctgtact attttcaaag gtaaaaagct atattctaga
    14941 gaattaagag aactgatggt ttccagctta ctccacaaaa cctgtaatat tttttgaata
    15001 tccacgttag catccatcgg tatattagca acaaatgtgt atcgattgtt tttaacagcg
    15061 acttgccaac agggaagaaa aatagtagca gatggaaatg gataatcagc ttgactgggt
    15121 tcttcaaaga aactaaaact acataagaac aggggtttag aaaaagctcg agcaatttcc
    15181 gaaaaacaaa cggttttttc cagacaatct ttgataaaat cttctgacgc cttgaagcgg
    15241 tttttgcctg ttatttctaa tttagcagca gcatcaaaag acgcgatcgc ttctttttta
    15301 cttttattct cccaataaaa attaatttgc tggggttgac ccagtttact aaatacaacc
    15361 agaggatcga ctgggtcaat ctctatcgaa acactagcaa tttgggtgca attcttcctt
    15421 aggcaatttt gctgaatcgc ccaaagaaag tggtatagct ccttattgta tacaaaaaag
    15481 tcagcgcgac attgtgaaac tgtcatgatc taaaaatagt aaattttttt gaagttatct
    15541 tccaaaagag tcataaatca tggtcgtatt tctacaggta acacaaacag acccttttaa
    15601 ccagagtgag ttttgcaaag ttgtagtttt gcaaaaactt gcctgcaatg tccagtttct
    15661 gctgtaattt gagactggga caaaaagtgg caacttctaa gttgttacct gtatagagta
    15721 tatttccaaa ccctaatttt ttttgggatt gggaattgct ggccatttta gtaaatcgcg
    15781 acaaatgact acaaagctga tttcttatcc caagaataag ttatggatgg cggcactcaa
    15841 accgccgatg tacagcgttg ctattatgcc catttgggtg ggtacagctg ttgcttttgc
    15901 tgaaacgaag acttttcatg gagcagtttt ttctaccttt gtagctgctg caatttgtat
    15961 cctagcttgg gaaaatctca gtaatgatgt ctttgattca gaaacaggga ttgataaaaa
    16021 taaacaccat tctttagtca acttgactgg gaataaaacc ctcatattct gggtgggaaa
    16081 cttattttta ttgctgggtt tgctaggaat attagcaata gcttggtggc aacaagattt
    16141 aaccgtcata ggtataatct tgttatgctg tgctttaggc tatacatatc aaggaccccc
    16201 tttccgtcta ggatatcagg gtttgggaga aatcatttgc ttttttgcct ttggtccgtt
    16261 agccgtatca gcagcttact acagtcaaac ggcaaattgg tcatggcggg cgttggtagc
    16321 ttcggtagtt gttgggattg ccacgagttt aattttgttc tgttctcact tccatcaagt
    16381 gaaagacgac atagccgcag gtaagcgttc tccgattgtc cgattgggta cgcaaagagg
    16441 agcggaagtc ttacagtggt ttacaggtag catttatgcg atcgccttca ttggagtgat
    16501 ttggggactg tttccaagtt ggactttact aagttgggca agtttaccct ttgcaagaaa
    16561 attatgtcac catgtccaaa caaatcacaa ccaaccagac aaggtaaaca attgtaaatt
    16621 tattgcagtc tcagtgcatt tttggtgctg cttgctattt ggcttggggt tcgtattagg
    16681 ttagtcgtta gtagctatta gccctccctt gtatctcagg agcacagacg ctatgtgcct
    16741 tgcacacgct ccgcgatacc gtaggctatg cccgtaaggg ctatacgcgt tgcgaagcta
    16801 tgcccgcaac ggcttacgcc agtcccagtg gtcgcgggaa acctccctga agcactggac
    16861 tcaccgccta ctttctctgg actcaccatt agctattagc cattagccat tagccattag
    16921 ctattagcca ttagccatta gccattagcc attagcaaaa aatgcattac caattccagt
    16981 tccgtcccta tcaacggaga tttgtgcgat cgctaaccac aagtcacgga gtttgggaga
    17041 ctcgcgaagg tataatcctc aaactcacaa atgatttggg cggagtgggt tggggcgaaa
    17101 ttgcacccat cagctggttt ggttctgaaa accaagagga agctctttcg ttctgtcgcc
    17161 agttaccaga agcgatcgca gacgaaacaa ttttttccat ccctgatgag ttacctgcgt
    17221 gtcaatttgg ttttgagtcg gctttttggg gactgagggc ggagaactgg ggattggggg
    17281 acaagggagt ttctcctact ttatcactca atccaaaatc cctaacatat agcgccctat
    17341 tacctgcggg agaagatgca ttggaggtat ggcgaacact ttggcagggg gggtatcgta
    17401 cttttaaatg gaaaattggt gtttatcctg ttactgaaga actaagaatt ttcaaaaggc
    17461 tcgctcaaac cttaccatct ttgacaaaac ttcggcttga tgcaaacggt ggattgagtt
    17521 atgaagaggc taacttgtgg ttgtggactt gcgacaatct taagactgac agtactttaa
    17581 atttagaaat tgaatttgtc gaacagccac tgtctgtaga taagtttgat tccatgttgg
    17641 aattgagcca ttgctatcac actccaatag ctttagatga atctgtcgca acactccacc
    17701 aactcgtagc ttgttaccaa aaaggctggc gagagatttt tgttattaag ccgggaatag
    17761 tgggttcgcc attccgtttg cgtcaatttt gcttggagtg tgaagttgat gctgtgtttt
    17821 cttctgtttt tgaaacttct attggtagaa aaccagcact ccaactggct gttgaattat
    17881 cgcgatacaa cagagcggtg ggttttggag tcaatcattt ttttgcagaa gaagaagaaa
    17941 tttggttgga aaatttatgg tagcaacgtt agagtatatc gtagaacagt ccttgcgcgt
    18001 accttcagat tggctaattt gcgattccga taatttattt cccctcatta tcaaacaacg
    18061 atatctagag ttaatgcagt tttcccattg gaaaacacct ccaaagattc tcttagccga
    18121 acccgaacca gtcaagtttc ttgcaagttt tcttgcagct tgtcaagcaa attgtccggt
    18181 tttcctttgt aatcccggtt ggggacaaca agaatgggaa caggtttttg atttagttaa
    18241 accagatatt atttggggcg tgaaccataa ggtatcggag ctctgcaaag agcaacattc
    18301 tttcccccca tccccctgtc cctccctatc cccgtctcca ctcatcatga tccctacagg
    18361 cggttcatcg gggaagatta agtttgccat gcatacttgg gaaactttaa tggcgtcagt
    18421 acggggattt aaagaatatt ttcaagtaga taacattaac tccttttgcg tattgcctat
    18481 ttatcatgtt ggcggattaa tgcagtttat gcgttctttt acaacaggag gtcagctggc
    18541 aattctccca tttaaagagt tagaatccgg acaaaactat aatattcaac cacaagaatt
    18601 ttttatttct ctagttccta cacagttaca acgtctcctg caaaatgcag aactcactca
    18661 atggctcgcc caatttcaga cagttttgtt aggaggtgcg cctgcttgga gcgaactttt
    18721 agaagcagca agatgccata aaattcgatt gggtctgact tatggtatga cagaaacagc
    18781 atctcaaata gcgaccctgt taccagatga ttttcttaag ggtaaagata gttgtacccg
    18841 tctgctacct catgccaaag tcaatattta taacgagaaa ggcgaaattt tgaagccaaa
    18901 tcaaacaggc aatattaaga tttcttctca atccttagcc cttggttatt atcctaatat
    18961 tcaaactaat tgggagtttt tacaaacaga tgatttgggc tttttagatg aacaggggta
    19021 tttacatatt tccggacgta gcagtgacaa aattattaca ggtggtgaaa atgtttatgc
    19081 tatagaagtg gaatcagcta ttagaggaac tcaaatggta acagatgttt gcgcgattgg
    19141 tgtacccgat ccggtttggg gacaagcaat aaccgcaatt tatataccta aaaattcaaa
    19201 tatttcttat ttacaaatta aggaattatt gaaaaataaa atgagtcgat ttaaaattcc
    19261 aaaaaattgg attaaagtag acagcttacc tcgaaattct caaggcaaaa ttaatcggct
    19321 acaggtacag gaattagcta gcaattttct gcaaaaaaat ctcagacaaa atcaagtact
    19381 tactccacct aagcatacaa atcagcatag cggttgcgat cgcgccaccg gttagaaatc
    19441 gcactcttta gaaatttagt ataaaatcat actaatttct tccccttcag atagtttctc
    19501 gcgattttct tctctctata ctttctgcac ctttacgatt tgtctccaac cattgcttca
    19561 tgttttcggg taactctgtt ttggttctgc tggatgtatc aatacagacg tgtctggtaa
    19621 ttgcttttgc agcgactacc tcaccaacaa taacttcata accgacttca aatctatccc
    19681 cactcagttg ttggggtatg agtctaataa ctaaattatc cccggagtac aatgggcgaa
    19741 aaaaatcgac atttgcatga acaatgggga atgcaataga tggattcgtg aaaaaatctt
    19801 tgagattcat gccaaaggtg gctagagatt cttcataggc ttcatggcat atggccaaga
    19861 cattagcaaa gtaaactact ccggctgcat ctgtatctcg aaagcgaacg gtgtggttgt
    19921 atgtaaaagc catattaaaa aattatggtt gtctattata tagcaggctg tttgcctgct
    19981 actgtaacca agtttaccaa ttatctgttg gttcgatcta aaggtgaata aatatcctca
    20041 gaatctggat ttaagtatgg acgctgtaga tcgataccca accgagcaaa atgctggtaa
    20101 attgctgaca tcctcttctc ggtagaatta tcgccgttct cccaagattc taataaagca
    20161 ttagccacaa tttgacaacg gttcataccg aaactttctt gagacgcaaa cttttggctt
    20221 ggttcttctg caagaccgag tcctggggct aaaaatttag tgaatagagg aatgtctttg
    20281 tgaaaatgag cttgatgctt cacatagaca gctttcagaa tttttcgcac tgctaaatag
    20341 tcttcgcgtt caaagtacag aattcctgag tcatagcgtc cgtaactaga gcgattgtgt
    20401 agaacttgaa aactaaatgg aatttccgca gaattgagta gccttgtaag actattcata
    20461 agagcgatcg cacctgttgg ggttatatta aagtaaattc gccccactcc aaaatcaccg
    20521 tttaaattga cttgtaaatc ctgaccgaca ttgctaactg ctatatagaa gccattttct
    20581 atacgatttt ttggcatcca aatggcagtg acttcaccta ctttagtaga ctggaccatt
    20641 gtttctaagt tggctggacg ctcaacgtat agtgttaaac cacctttggc tactgccata
    20701 ctaccatcag gttcttgtcg caagacttcc caaccagaat caaaataacc aacaccgtgg
    20761 ttgctactgt gtagttgttc gtaaaacggt aagtctattt taaattgaga atcgctctct
    20821 aagcttttgt gtggaaggtt actaggacaa ataccatttt tttctataag tatctttttt
    20881 agagaaccgt tgtaatagat accgtgaaga aaattccgca gtaatagaga gagatatttt
    20941 tgttgtaaac tgggcgaagt ttgctgaaat ctacctgcta cttgttgtgg taaggcaaaa
    21001 ggttggtatt taggatggct aatgcaaaag ctcgattcaa tttggatatt gctagctata
    21061 tctaagagag attttaagag tggttttgaa gattttaaca tgatccggca aaaagggagt
    21121 ggctgagtga atgagggaga gaggaaaaga ggagatgaaa atgattaaca gccgcgcaaa
    21181 cgtgctttat tgttgtggag acgcagcaaa ttgacttctt tttgtgcttg cgaaaatttt
    21241 gtaagtttta caaaaggttt gatgagatct gtttctgaaa ctccaaaaac agtcatcaca
    21301 gattcttgcg gtttggtcag taaacttctg gcaatttgaa acgtacatat gcctgagtta
    21361 tcaaagtagc gatgctgctt aattttttca tctattttat gaagcagcgc taaacccgca
    21421 aattgaacgg tacggagaag aaaatcattc ctctgttcaa gaattgttgg aaaagtgtcg
    21481 agataagcct gaatcagagc caatattgaa ggctgaagaa tgtcgaatgg aactgctgat
    21541 agatgcagag attcatctaa atctaaagaa gggtctacta ccaaactttc taacccaatt
    21601 gccaaataat cggctactaa agttcccaag tcaaagctgg gatcgcccca agcgcatgct
    21661 tcccaatcaa tcaatcgcac cagacagttg tcgagttgct cccacttgga atgaagcaaa
    21721 atgttgtcca atctcaactc attatgagtt aaacagcaag gcttccattc ataagataat
    21781 tctgcgatcg ccccttctat ggtttcatag cgttggtaga gagtgtagaa ttttaaggcg
    21841 ttcgtgggaa cgcgactaat aatttccggt ccaatggagc caagtccttg tgctggatta
    21901 tataaatgat agcgatactc accttctggc gcagttgcca taaaatcgcg atactcgtga
    21961 tgcttgaagg tcgcacgatg caataatccc agactggtac cgatcgcagt agcaatcgag
    22021 ttgggaaagc gcaagttttg tcgataaaaa ctagcagtgt cttgatagtc tttaaggtaa
    22081 ttgcggacta agatagactt tttcctatca aagtacacca ccaatgatgc gatcgcagaa
    22141 atactcccca aagcaggaaa gcgttcgagc aattggtgaa acagccattc attgaaaaat
    22201 tcctgtggtt ttccatcatt atcaatatgg cgttcctgtt taaccaacag ctggcgattt
    22261 cctttcagag taacgagcaa attaaaattt ttcttgctac tctgtggcaa ttcagagtcg
    22321 gtagaaacgc cttcttctga gctacacaga cctgcttctt gcaagtcctg gataacatta
    22381 tgagaagaca gtgaggttaa catgcactat ttccactcat cgaaagattg cttagacaat
    22441 ttgttgtaat ggaggttgtt tttccttcag taataagtag atagcagcaa gcctgatatc
    22501 gatacctgtt tgtataaact attaatatct tattttaaaa aatgacactt gccaaaatgg
    22561 caatactcac tttaatctgt ctttaaattt taactaaaaa gatgttaatc ctttaacatt
    22621 ttaaacagat ttacgtataa acagaaattt tgatgtttgg catttgttcg attgtaacct
    22681 ttcctaattt ttaaatgaca cgggaatata cttatccact ttttacagtg acaccccaca
    22741 gtacaggaca ttccagttaa tttccggata tttcaaatga ttttcttata cagcaagttg
    22801 ctgtcgtcac aagtctttgg ctcgaaacga gcgtttagaa aaaaatttgg aatttcaatc
    22861 tttcttaagg atgatattgg tcgatgttga tttggtttca atacgctgat ttttttcccc
    22921 aaaagagtca gaattttctg taatttaagc aaccaattat cggtaacacg agcagattta
    22981 gaaattaaaa gaaaacttta ctgattgtta agcttaagag acattttgta ataaatccaa
    23041 aattcagcat ccaacttcat tgcaagacca acagcaagaa acacacatga atcgcaataa
    23101 ttggcaagaa agtttttgtt aaatttttta ccatgaagcc aaaaccagga cggatctcgt
    23161 agcacggtaa aggtaacagc aagcctttgt cgttactctg aatcgctgca ttacaaacag
    23221 aatactctct ttggagccgc gaccctgaag acgaaatttt agacacagtc agagagttgg
    23281 gtattgggtt tgttgcttac agtcctctag gacggggatt tttatcggga gctattacaa
    23341 gccctgatga ttttgcagaa gacgactatc gccttatgtc tcctcgattt caaggtgaga
    23401 acttttacaa gaatctagaa ctggtgaatc aggttaaggc gatcgcagct gaaaaaggtg
    23461 caacccccag tcaactggca ttagcatggt tgttagctca gggtaatgac attgttccca
    23521 tcccagggac aaaacgacgc cgatatctag aagagaatgt aggagcaaca gaaattacgc
    23581 tcacaccaaa cgatctgcgt cggattgaag aagttgcacc caagggattt gctgcaggcg
    23641 atcgctatcc agttcaacat atgagtacac tcaatcttta acagtcgcct atcccaagcg
    23701 caatattctc acaaagaata gcaagaaatt gttgtaattc acaagaattg gcaagacaac
    23761 tcatacaaag tcttttactg ttgaatacag taagtacggt taacaccgct tacctttcat
    23821 aacaggataa tgcagggaac agattacaat catggggctg gtgctctatg attgttttta
    23881 taattatgaa gtccaagcag ctagacatat ctagtgaaaa ataatctcaa gacattgcaa
    23941 actgctcgtc ttaacaaggg ttgtacgcaa tgcataattt ttttgtaaaa tattatcatt
    24001 atcatttcga ttgagaaagc attggcttgc atttgtgtca aatgaccttg ctctttttca
    24061 caagcgatcg attgccaact tctaccaaac gcaactatcg aacgtataga gcccctttct
    24121 ctgtaagtag gtcagtatta aaaattatcg tcatgacaag gcagatggca gagggcagat
    24181 ggcagaaggg aagaggtttt taggcaactt tacttttcgt tacatagttc ggtttttttg
    24241 cgcctttcta cttaaaagat acttttaatc acttttagtt ataaatttaa ataaaaataa
    24301 tgtttgattt tatagaaccg cttttctaaa gtagtgagta agaagtttag tagtggctcg
    24361 tataaaacta aagccttgga aggaaaaatg aataaatcca attctcaaaa attaacaaac
    24421 tggcttgtaa cagcagtctt tctagtactc gcagtcactt tttcattgtt cgatcagcca
    24481 agtgctagcg ctcaaacaca aacaccaatt acaaccacac aatctacacc agcacccatc
    24541 acatctgtag cagcaaacat tagacattta ctagaaacca acgagtgtgt gggatgcaat
    24601 ctcattggag caacattaaa agacgcaaac ctacaagctg ctaacttaga aaatgcaaac
    24661 ctgcaaaatg ctgacttaga aagagcaaat ttacaaggaa caaacttgca aggcgcgaac
    24721 ctgcaaggtg cagatttagg taaggcaaac ataataggcg caaacctagc aagtgctaac
    24781 ctatttgatg cggacttaga gaaggcaaat ttaacaaacg caaatatatt gggagcaaat
    24841 cttcaagggg ctgatttaga ggatgtggta agaccccaag gatttgccat tcagtaactg
    24901 ctctctctag agaaatataa aggctcattg ttatgtcaat tccgcctaat tactgaaagt
    24961 aattgggcgg aataacttta acaataagaa atttcttgac gatcgcggaa atacttaccg
    25021 ctgtcgctta atgaagcttc tgtcgccagc caaagagcag tatcagcccc ttcttcaggt
    25081 gaccgtggag cagacgcacc acccatatca gtcctcaccc aaccgggaca catagcgtaa
    25141 actgcaattc tttttggtct taaagcttca gcgagcataa tcgtcgcacc gttaagtgct
    25201 agtttagata agcaataact ggggacttgt gctgaaagac cgccgatctc tccatatcca
    25261 ctcgatacat taataattct ggcactggat gctttttcta ataaaggcaa gaaggcttga
    25321 acgatactaa taggacctag ggtgttggtg tttaaagcga catccaacaa ttcgcgagaa
    25381 atgttgagaa tattcacgcc ttcatcggga taaattgctg cgttgttgac aagtacatct
    25441 aaatggttga tttgttggga taactctcga acggcgtcgt gaatggagct atcatcagtg
    25501 acttcaagaa caactggtct gacgttggat ggtgaagata gtttttctgc agcatcccgt
    25561 gcttttgaga gcgatcgcgc tgctagaatc acctcaaatc cagcattcag caatccctta
    25621 cagatggcaa acccaatccc tttattacct ccggtcacca gtgcgtattt tttcgcaggt
    25681 tttgcgttca tctaaaacct catggaaacg tgcaaaccat ttgtctgtgg ctcttcttcc
    25741 tattgcctcg ctgttcttaa gagattgtta cataacaacg cgcctcacaa ataagaattt
    25801 tttgacaata gactatttca cgcagatttt cttgtacatt attgcgatac aaagtagatt
    25861 cttgcagtaa acattcccca aacataaatt tttttgagat gtaggggaga cagaagtgcc
    25921 atgtggatag aagttaatct tctatacctc tttagtattg gcacaattat tatgtcatga
    25981 attgatgaca taaagaactc cagtcaataa caaaaaagca gaagatcggc tctgatgctt
    26041 gaaatacggg tcttgtattc agttatggaa acttcagaag cagtcgcttc gagtttcacc
    26101 agagtagacg cttttgagca aattcgtgtc aatatatctt caatggcaca aaagtcaaaa
    26161 tcttgggagg taaccgtatc aaaactccat tcataaggaa atatgcagtt tacactcggt
    26221 ctactcggta ataaccagat attgagcata tttggctaaa ccgggaaaag taatttacag
    26281 caagcaaccc tcgctcttac tatagattga gttagtcatt acaataatgc aggtctctta
    26341 gcattaatta atgttacggc tgcaattatc ctcagcactt taaggagtgc aaactcgttt
    26401 cctcgaaaac aattacacag tatttacaat ttcagtggaa aatctcctta ttctcagagg
    26461 aattcaatgt ctaatgaagt gcatgaatca gaagtgacgg ctcgcttaac tgcgatagaa
    26521 ctgcagctaa agcaattcaa tcagctgtta tcaaatctca gcgatcgcat tgctaagtca
    26581 gaagataatt ttctcctcat tgccgatatc cataaataca aaaaactgca agaactttta
    26641 atagtaggag acttaagaga agccgattgg gaaactattc gggttattca agcaataaca
    26701 aaagagccag aattgggaga tattactcca gatgatatga ggcaatttcc ctgtgatgaa
    26761 ctgcgagtga tagacaattt gtggacaaaa tacagtgaag gtcgctttgg ttttagcgta
    26821 caaataaaaa tttaccaaag cgtgggtggt tccctcgaaa gcaccattaa tcaagatagt
    26881 aaagccatcg agcgcttcgg cgagcgtgtg ggatggcgtg aggacaatcg atggaaaaag
    26941 tgcgatgatt tggactatac attagctgca ccaattggct gtcatccctc gcgatggtgg
    27001 aattctcctt ttggttcaaa aatgaccaac tatttcttca atcgcctgct agtttgtagt
    27061 atttaacgaa cggtaactga tgaccgatga ccggtgacca aaagtagagg atttgaataa
    27121 tgaatgaatt ttgggttttc cattaataaa ttgagaggct tgttttggat atgtaaccgg
    27181 tcatttggaa ttctaaagac tcgctttaac ttatcactcc ctttacctca gttgaattct
    27241 tttgaggtca gaatatgtct aaaaaatccg acactctatt ggcttgtaaa gtattatttc
    27301 cagttcttct ggtctccgcc ttaacaagcg cttgcagtca ggacaaaccc aaagccacag
    27361 ccagcgaacc ccaaccaata ccagtgaaat tgcagtcatt gcagtcaaca acactacaag
    27421 atgtctcgga attcgtaggg aggttggaag cgcaacaaag agtctcgttg cgacccgaaa
    27481 tcgaaggtcg gatagaatcg attcccgtcg cgtcaggcga tcgagtcgag caaggaacgc
    27541 caattgtgat actgcgacca gatcgcactc aaccagaatt actgagtgct gtggctagag
    27601 ttaactcagc taaatccgcc tacctgacag cgcgatcgca actcaaagca gcagaagcgc
    27661 agcaagttag agatgcagcc gatgtagagc ttcaaaaagt tgagtttcaa aggacgcaga
    27721 agttagtgac tgaaggagca caggctcaac agcagttaga catagcccga aaaaacttga
    27781 acacagcact agcgactctc cgcgctactg cggagcaagt aggagctgct aaagccagcg
    27841 tcaagcaagc agaagctaat gtccgacaat atgaggctga tacggcttct gctcgcgtgt
    27901 ctctccaatt caaacaagta ttagcaccaa ttaccgggga agtaggagac ttccccgtta
    27961 aggtaggaga tgttgttagt gtcggtcaga gcctaaccac gattactcaa aatgacaatc
    28021 ttttcttgcg aatttcaatt cccagcaacc gctcctcaga aataagacgg gggttaccag
    28081 tagagctcgt agatgccaaa acaagaaaac ccttgagcac tggaactatc aactttatct
    28141 cgccagaagt agacacgggt gctcaagcta tcttaaccaa agcccgcttt tccaactcag
    28201 gtaacaattt acgagaagga caatttgtcc gcgcaagagt tatttggaac aaacggtcgg
    28261 gtgttttgat tcctaccgta gctgtatcca accttggagc acaaagcttt gtctttgtag
    28321 cccagacaac aggttcaaaa caaaccgtgc gccgtcaacc agttcaactt ggagccattc
    28381 aaggtcaaag ctaccaagtc attaatggtg tgaaaccggg tgaccaaatt gcagttaccc
    28441 aaattcttac tttaagggat ggcactccaa tcaaagctaa ctgaactatg agttatgaat
    28501 tatgaaattt tcaattcata attcatcatt cataattcat cattcataat tcatcattca
    28561 ttatgagtat tgcggatatt ttcattaggc gacctgtttt taccacagtt tgtactgtaa
    28621 ttattctctt agttggggga atctgtattc ccctgctccc tttggataag ctcccagaaa
    28681 tggctctcaa gcaggtaact gtgactgcta actatttggg gactgatgcc aaaacagcag
    28741 aagaaaacgt taccaccgta ctagaacggg aaattaacgg tacggaacgg gtcgtttaca
    28801 tgtcctccca gacgacgaat gatggcaatg ctactattaa cgtctctttt cctacagaga
    28861 tggatagaaa cacagcccaa gtcctcgtcc aaaataatgt agcgatcgca gaaccaaatt
    28921 tacccgaaga agtcaatcgc attggtgtaa caacgcagaa gcagtcacca acgattaccc
    28981 tcgcttatgc tttctattca gaaaaagacc agaatggaaa atttatctac gataatatct
    29041 ttttaagcaa ttacgttgac cgacaaatct ttgacgaaat taaacgaatc cagggtgtcg
    29101 gttcgatcag aattgtgggg gaacggaaat acgccatgcg tatctggctc gaccccgaag
    29161 cccttgctgc tagaaatttg acatcacaag atgtcattgg cgctattacc gaacaaaata
    29221 ttcaggtggg agcggggaga attggccaac agccaacttc aacagagcag cagtatgaaa
    29281 ttgctttgcg agctaacggt cgatttacca ctcctgcgga agccgaagat attgtggtca
    29341 aagtcggtca ggatggtacg ctcattcggt taaaagatgt cggtcgagcc gaagtagggg
    29401 cggaaaatta caacgcgaca actctgtttg acggttcgcc ggctgtcatt ttgttagctt
    29461 accaactacc cggtacgaat gcttggaaca cagctaacgc cattaaagca aaaatggcag
    29521 agctgcaaac taattttcca ccaggattaa aggcgacaat tggtttagat aatactttgt
    29581 ttgtggcatc ttctctagat gaagccttta aaaccctggt tgaagccatc gccctggtgt
    29641 tccttgtcat ctttatcttt ctacaggatt ggcgcactac cattattccc gctctcgcca
    29701 ttcccgtatc gctgattggg gcaatggcaa ttgcctatgt gcttgggttt accttaaatc
    29761 agttaacgat atttggtatt atcttggcaa caggtttggt ggtggatgat gggatcgttg
    29821 tggtggaagc gatcgcagct aaactcgaac aggggatgaa accccttcaa gcagctctag
    29881 atgccatgaa agaactgact ggggcaatta tcgcaacatc agtagtactg atggctgtct
    29941 ttatccccgt aactttcttt ccagggacaa cgggtatcgt ttacaagcaa tttgcactag
    30001 taatcgcttt ctccattgcc atttccacct tcaacgcctt gagcttctct cccagtatgt
    30061 ctgctatcat catgcggaga cagcaggaag ttcacggtcc tttaggcgtg tttttccggt
    30121 ggtttaaccg cgtgtttgat tggtttaagg ggggatacgt caaaatcgta gaattcctga
    30181 tccgggttcg atggctcgtg attccagtat ttcttgcggg tttatttgca acgggttgga
    30241 tttatcagac gactccccag ggatttatac ctgaagaaga tcagggttat ttctttacaa
    30301 ttgtggaagc tcccccaggg gtctctctca actacagtgt cgatttagtt aagaaaatta
    30361 ctgaggaagt cgtgctacca cttccggaag ttgagcacgt tgttggtaac gctggttttg
    30421 gttttgaagg gaacgccagt aacaagacac tgtttttcgt caagttgaaa gattggcaag
    30481 aacgtcatgg tgcagagcat tccatttttg gtgttctgcg aaaaatcaat aaagggttgc
    30541 gagaaaaaat ccctggagcg atcgcgatcg ctgttaacgc cccaccagtg gatggtttgg
    30601 gaagtacagg cgggttggag atgtacatcc aaaacaaaca agcacttccc atggaagcgc
    30661 tcatcgacaa tacccaaaag gtaatagcag cagcccagaa gagaccggaa ttaggaggtg
    30721 tctttaccca gttcaccttc aacagcccga tgatgcaaat ttccatcgat cgcaatcaag
    30781 ccaaagctca gaatgtccga gtgagtgata ttttcagcac catgcaaacc tatttgggtg
    30841 caagctatgt caaccaatac gtgcttggtg ggcggttgta tcgcgtttat gctcaggcgg
    30901 aggggacaat tcggtctaat cctgatgatg ttagtcgtct gtacgtgcgc tctcaggatg
    30961 gtaacctcat tcaactgagt actttggtac aaatggaaag attaacctac ccgcctgttg
    31021 tcactcactt taacgtttac ccatccatta aaattcaagc ttctccagca ccaggataca
    31081 gtacgggaca agcaatccaa gctatggaag aagttgcgaa ccaagtttta caaccaggat
    31141 ttggttttgc ttggactgga accgcctttc aggagagatc ttctagtggt gcagcaccaa
    31201 ttatttttgg cttagccttt gtcatggttt tcttagtgtt agcggcgcag tacgaaagct
    31261 acgtcgatcc aactatcatt atgattaccg tacctctggc aatcttgggc gcactcggtg
    31321 cgatcgtgtt ccgcgccaac attttccagc aaggtggtgt ttggcctacg ctaaacaata
    31381 atatgtatgt tcaagtagcg ttggttatgc tgattggtct ggctagtaaa aatgcaattt
    31441 tgattgtcga atttgccaac cagtcagcag agctaggaat gaactacacc agggctgcaa
    31501 tccgcgcttg tgaagaacgc ttgcgaccaa ttctgatgac tgcttttgct ggtttagttg
    31561 ggttttggcc attggtgata gcttctggtg ctggagccat gagtcgatgg gctttaggaa
    31621 cagcgctgtt tggtggttat ttgatttcaa ctgttttaag tttgttttta gttccagtct
    31681 tgtacgttgt tatcaaaaac ctagaagacc gcttcttaaa acctggtaaa cccggtaaac
    31741 ccacaagtcc gtcacagcct tcagatacac cccaaccaca agaacaagta ctccctgcat
    31801 tccgtggata ctccaccgaa gagtgattgg tgttcggtaa atccccatac ttgaaagtag
    31861 gggatttaaa cgctcgctct cttttttcaa aacatcaatt gcaaagcaaa atgaaatgcc
    31921 ctcagaatag aattctggac ggcaggcgct atctccttac ggagacgctt cgcgaacaac
    31981 ggggggaacc cccgcaacgc gctgcctcgg ctatacaaac gctcgtccgc ctaagcgcaa
    32041 agcgcacgct acgcgatgcc gcaggctatg cccgtaaggg ctatacgcgg acttaataaa
    32101 aagttcacgt aggcgggttt cccacgccct ggggactggc aaacccgaag agactttgtt
    32161 tatatagacg cgatttccaa tggctctagt aatattatcg atcgtaaagt tgagaatttc
    32221 aaagaaagaa atagtgtaca attattttga gaaaagtaac ctttatgtgt aaaggtaaca
    32281 aaaatgttta aaaaatggaa tgcagatgat tggataaatc acatcttgtt tacaattact
    32341 gttgtatatc tattttacaa tttcttcttg catcactagc tcttcagtca atgaatttta
    32401 acaggctgta agaaccccga attaagagtt cttcgaggtc ctgcaaaccc tcatttttac
    32461 ctacctatga atcatctcaa catgaggaaa tcatgaatat taaactgatt attttctcag
    32521 gtttgataac tgctggaatt ggctccgtaa taggcttggc tgctgctcaa attggtcaga
    32581 gtaattttaa tgaattgaaa tttgaaggcc agtattacaa agatttgcat aacagatatg
    32641 ccttaattgg tgctagcgta gggctagttg taggtatggc acaagagtgc gtgcgagaga
    32701 tgaaatctca aagagaggaa gagtagaaat tagggattct tcacggaaga caaatgaaga
    32761 ttaaacacag cttaatttgc ttgttaatta ttgggacaac tgttttgact gcggcaaatt
    32821 ggcatttggg tatgatgggt atgacaacat ttttattagc ttacttctct aaaggtttga
    32881 gacgccgcag ccatattaat ggcagacttg caaagtagga atatcccaat ttaagatagg
    32941 tccgatggga ataatccgtc gattaattaa tccttcgtag gtatcgtaat aatgacgttt
    33001 gatatggtca aattttacgg tgtctgacac gtttggtaag tgataaatgt ggcgcgtgta
    33061 attccacaaa ttgggataat ctgtcagacg gcggagattg caattcaagg ctccgtagta
    33121 ggcgacatca aaccgaacga gtgtgacaaa aagtcgaata tctgcttctg tgagagaatg
    33181 acccaccaag tattgctgac cgcttaaccg agtttccaaa atatctaaag catcaaacaa
    33241 ctgcgcgatc gcagtgttgt aatctaattg agaactggca aaaccaactt tataaacacc
    33301 gatgttgatc cgatctgata caaatgcatt tatatcatca atctctgctc gcagttcttg
    33361 gggatagaga ttgagactcg cattcccaaa cgcatcaaat tccgtcacca acatacgcaa
    33421 aatatctgca gattcgttgt tgacgattgt tcctgtttgc ttatcccaca aaaccggaac
    33481 cgtgactcta cctgtaaagt ttgattttgc tttaacgtaa acttgataca ggtagtcaca
    33541 accattaacg gtatctgctg ttgtatggct ccagtcccca aatgtccatc cgcttggatc
    33601 tccccaatcc gggctgagga cggacattga aattacgctg tttaattgct ttaattgacg
    33661 agctagaatg gtgcgatgag caaagggaca ggcgaaagaa acatataagt gatagcgatc
    33721 gcgttcggct ttaaacccag aagaaccatc agcagagata aactctcgaa aagaacctgt
    33781 ttgtattctt tccccttcaa gcggttgaaa gtcagaatgc caaacaccgt ttactaatag
    33841 tttcataaaa cctccaaaga taggttcact aaagtgtgaa ggataagatt tgatttttta
    33901 tccttcataa ttcaatcgat tttttttcaa agttgcttgg ttgtttattt gcaatgagga
    33961 aattgctacc acaatcagaa ttccacctgt gatttgaagc agagtaagat attgtccaaa
    34021 ccaaatccag gcaataattc cagcaatgaa cggttctatt gaagcaacga tcgcagctct
    34081 ttcagcttgt acgtgacgaa ctccccacaa aaacaacaga tagggtaaga gcgttcccat
    34141 gatacccata tagagaatct tgggagcatt tatgacttct agtaaatgag gcgtcaagcc
    34201 ttgagtcagc aaaaagccaa accaaataag gctcgcaatt gaaaacgttt gcagcagagc
    34261 gttaacaggt gttccttgag cgccaatctt ttcactcaat agagtgtacg ctgcaaaaag
    34321 aatcgccgtt gttaaaccaa ttgcaatacc aaaccaattc acttggctta aatccccgcc
    34381 taccacacca gacaccagga caacgcccaa aaaggaaagc gccagagcaa tcaaaacttt
    34441 tgcggaagga acgcgccgcg ataggagtgc gttccacagc acgacaaaac ccggagccat
    34501 gaagatcagc acgatggcaa tagcaacagg aagttttgcg atcgcgagat aatctgctcc
    34561 cacgaacata acaaacaaag cacttaacgc aatttgagaa agactcggta ctctcaaaat
    34621 aggatgcttc tgcaacaggt tgagcgccat tagcccaatg gtagcaagta tggcgctgac
    34681 tcctgctagc tcaaaaggac ttacgcctcc ctcaaataaa ctgcttgcga cattagcggc
    34741 gagcgcccaa aatgtcgaag ctccgaccac cgcaaaaaga ccgaaaggat tctgcttctg
    34801 catttgtgtc tccatgagtc aaacgactca ttttatagtt gaagctgcaa ttattgcatt
    34861 tacaactaaa ttaaagataa tatgcaataa ttgaaattgc aactactttt ggagaaattc
    34921 tttagactga tggcaaagca gcgattagac gaaatgcgaa actccacttg gcggctgttt
    34981 ctcactgttc agattcaagc gatcgagaag attcaagaaa aactatcggc tgcgaaactg
    35041 ccaccattgg aatggtacga tgtgctgtgg gaactcaaaa aagtaccaga gggacgtttg
    35101 cgattgagcg aactcgcaga acgagtcctg ttaagccgga gtcatctcac ccgcttgctt
    35161 gatcgcctgg aaaaaagcga gctattggag cgacaaccct gtccgagcga tcgcagggga
    35221 acatttgcag tgttaactga agcgggtgca gcaatgcaag aaaaaatgtg ggctatctac
    35281 tctgaaggaa ttgcagaata ttttggcgat cgactgagtg atgaagaagt caaagttatg
    35341 caacaagcac tcaaaaaagt tcttggagaa aattctactc agaagtaagc atgaactacc
    35401 cagagataat tcgttgaggt ttgggtttct gcaagaatgg cacttagaaa agctataagc
    35461 atacacaaca agtgatacag cttttaatgc cagagagtgc ggtaatagaa cgatccaggc
    35521 gatcgcttcc aaaaagaaat ttttgaagct agaaaaagcg tactcgtcct taaaaaagca
    35581 atgcaacaag cttttaatac caggacaatc gaaagcatca tacttctgaa tggttgattt
    35641 aggcaatgtc gctaatcgtt gtgttaccaa cgaaatgcag gaagaaatct atctcaaggc
    35701 agcgagggct tccagaattg cgttgacgac cctatccggt cgatcgaacc atggtgcgtg
    35761 ccccgcatcc ggaattcgca ctaccctcag ttgcgggttg ctggcggcta cagcttcccc
    35821 cacttcgggc tgacaccata cgtctttctc accccagatt aacgttgttg gaaccgaaag
    35881 ctgcttccag cgatcgccta gcaccaactt ctgcttcata ccgcgaacat ctaccgtact
    35941 gtcgatcagc gtgaaccaat ttgtcacatt gcgggcttga cttgccgttg agacatcgag
    36001 aaagtcatca tcaagacgct ccggatgggc taccatcaac tgcgcccaga aggcgcgagt
    36061 actctcgcgt gttggtttct gcatctgaga acgcacaata gtcttcagga taggcagtgt
    36121 gcccaagcgc atcaggagcg gctgagagcg ctgaattcct gccggagcgc cgaccaaaac
    36181 caaacgtggg actcgctctg gatgagagag tgcaaaggca accgaccaca gactacccat
    36241 agaacttgcc acaattggca cggcaggaag tccctcggta tcgagaatat cgccaagaaa
    36301 tcgacatgca tgagcaagta tatctactcc ccgatagtca aatgcatccg cgagtccgtg
    36361 acctggtcga tccactgcca gcacgcggtg actcttggcg agagccgaaa ggatacttcc
    36421 ccactgaaag gcttcaccca tacctccgtg aacaagaagc aggggagtcc cttcgccaag
    36481 ttcgattacc tgcgtcgtcc cacctgacca atgcacccga cgagtgcggt atccaggcgc
    36541 acagcgatcg agataagcag cttgagccat ctcaacactc tgagtcttca tgtcagattg
    36601 catcctaccg ttttccctcc cctatggacg tttcctcgat cgtttgttgg aacttctata
    36661 aataaagcgc caatccattc tactttgtac ttaatggtac tgcgaagcat actaaaaata
    36721 gttccattag gtaggtgata gtatgttgaa atgtaaacct tttgttatag cgcttgattt
    36781 ggaaggaaca ttaatatcaa atgtaatcct tgggtactct aaaagggttg tcgaatgaat
    36841 atgagttgaa aaaagtgtta aacaacgaat tagagacatt aggatggttg gcaattgctc
    36901 aattagcaat aattattatt tttggcttgt tattctccac tatcgctaaa ttcaaatatc
    36961 aaaactcttc agcatcccat cgggttttta aacaaggcga ttacacttca tgttttattg
    37021 aagatcctca agttatattt caaacaatac caaaatgcta ttactttgtt gttgttaact
    37081 atcaaccgaa tgatcaagtt atccaagaaa gtttttatac aatacttggt gatgtaacat
    37141 ctataaatta ctctgatggt aaatgggttg ctacaaagtc taatctttat tccaatatgc
    37201 tcttagttgc actgcccttg attggtttta tcttgatatt gtcatctaat ttggtaactc
    37261 aatctgtttt agattcagtc attacaagac aaagtgatat aaccgaacaa ttgacgaact
    37321 atggaacaat attgttcggc tcagtttttc tttcagctcc aattaaaatg atttttgatt
    37381 tttttaatca ttttaagatt taagaagcca gtaaaattat gatttctata aaaggcaata
    37441 ggcgaaactc aaatgtctga tattggtttg attttactag cggcgggtgc atctacccgt
    37501 atgggtacac ccaagcaact gctacagtat caacaacaca gcttgattcg ccatatggtt
    37561 gaggtagcgc ttgcttccgt ctgcaacccc gttatcgttg tcttgggagc atatgctgag
    37621 tgtattcgac ctgaggtgga gttatctaat gtccgaattg tggaaaacga tcgctgggct
    37681 gaaggtatga gcacttcaat tcggtgtggg atggaagccc tcaatgaaat taaacctggt
    37741 gtagaagctg ttgtattgat gctgtgcgat cagccatttg tttctactca gatcgtcaat
    37801 caactggtta acatcttcca agagacagat ggacaaatta ttgcttcaga gtatggagga
    37861 gtccggggtg taccagcgtt attcaaacgc aatttgtttg cagaattact gacacttaat
    37921 ggtgttgctg gcgcaagaca ggttatcaaa caaaatgctg agaaagttgt tagtttttct
    37981 ttcccagaag gtatattcga tcttgataca cgcaacgact acgagcaatt taaaaatgca
    38041 atttcaatct gaagggagtg gaacgagata aagaaatgac aggggctttg ttgcaaaaat
    38101 tttggtaatg ttctgctctt gtgctaaact gctctcactc aaagtcggga gagcctttac
    38161 ttaaaactta tgcatcgtct tgcaactaca ccaggaggtt ggaatccatc agcagaaggc
    38221 gtgatggcga tcgagcaaca accagcacct attgttttaa ttacggctgc ggataccgac
    38281 attcaaactt tatctgttgc tgttactcaa ttaccctcag aatttctaca gttacgggtt
    38341 gtcaatttac tacaactcca gcaacaactg acaattgata tgtatgctga agatgtgttg
    38401 agtgcggcgg aagtgattat tttacggttg cttggcggta gagcttattg gagttatgga
    38461 ttggaagttg ttgaacagac ggttaaacag acaggcgcaa aattaattgt cttaccagga
    38521 gacgaacgac ccgatctcaa tctcataagt tgctctaatg tttctttagt agacgccaat
    38581 cagatatggc agtatttcaa tgaaggcggt acggaaaatt atcttaacag tctcaaattt
    38641 atcgctacaa cttttctcgg ttgcacctac acctttaatt taccccaacc agttcctcgt
    38701 gtgggaacat attcacccag cgatcgcatt atctacactc aagtagagaa taatttcatt
    38761 cctgtacgca aaccagattc tcaaatcggt gttattggta tcatctttta tcggtctcat
    38821 tatttagctg gaaatacatc agtcattgat gcactttgtc aagctctagc acaaagaaat
    38881 cttacagcaa ttcctatttt tgtttcttct ttaagagagc cagatgtcca agcggagttg
    38941 ttaaaatatt gcagtcaaaa gatagacctc ttattaaata caactagttt tgctctagca
    39001 aaattagaag cagaaacacc acaagtagaa ctttgggaac aattagatat accagtgtta
    39061 caagtcattc ttagcggtag cagtcgcgaa cactgggaat ctggttcttc cggactcaca
    39121 ccaagggata tcgcaatgaa tgtggcttta ccggaagtgg atggcagaat tattactaga
    39181 gccgtctctt ttaaagcagt caaaactccc agccctttac tgcaaactga tgttgtcagc
    39241 tacgaacctg ttgcttctcg gattgaattt gtggcagatt tggctgcaaa ttgggtaaaa
    39301 ttacggcata ctccaccaca aaatcgcaag attgccttaa tattagctaa ttatcccaat
    39361 cgtgatggac gcttggcaaa tggtgtggga ttggacacac ccgcaagttg cattgaaatt
    39421 ctgaaggctt tacagttagc aggatattat gtggataata ttcccaatac gggagaggaa
    39481 ttaattcaat tattaacaac tggtgtcact aacgatttag agggataccc attccgagaa
    39541 gtacggcaat ctttgtcttt gcagaaatat ctagagcatc tttatagttt acctgaagca
    39601 gtacaagaag gactaaaaaa ccgttggggt ttccctgaag aaaccgattc attgcccatt
    39661 tcgggtatac agttagggaa tatatttgtg ggaatacaac cttcacgggg ttacgatcgc
    39721 gatccatctt tgaattatca cgcacccgat ttggagcctc cccacagcta tttggctttt
    39781 taccattggc tggttgagtc ttttggtgca aatgcgattg ttcatgttgg caaacatggt
    39841 aacttggaat ggttaccagg caaaagtgta gcactgtctg agaattgcta tccagaagcc
    39901 gtcttgggag caattcccca tctctaccct ttcattgtta acgatccggg tgaaggttcg
    39961 caagccaaaa gacgttctca agcaacgatt atcgaccatt taactccacc catgactcgt
    40021 gcggaattat atggtaattt atactctttg gaaggattga tcgatgagta ttatgaagct
    40081 caaagtttag agccatcacg attacctgca attagcgatc gcataactca attaatcgag
    40141 cgggagcatc ttcatcaaga tttggggatt gatatttctc gtttcgataa atcgactctt
    40201 tcttcatttc tcaatgcagc tgatggttat ctttgtgaat taaaagaagc tcaaattcgg
    40261 gatggtttgc atatttttgg tcaatgtcca tcaggaaaac aattacgaga tttaattgtt
    40321 gctattgcca gaaatcccgg tgttggtaga ttgggattga cgagggcgat cgcgatagat
    40381 tggcaattag atttcgatcc tttaactgta gatttcagtc aagcatttga gattaatttt
    40441 cctactttga ccctacccga aacctcattt taccgggagg tgggaactgc aacttcagat
    40501 ttgactccac cccaatcccc atccgatgga gaagcgggag cttcagacgg ttcctccctt
    40561 tacaaggagg gattaagaga actcagtgaa agatatcaaa agctgaaaaa ctgccgaatc
    40621 ataggtgatg ttattcaaat ccttgaagat tgtgcatcag atctcgtcac ttatatcatt
    40681 gaaaatgaag aaatcccgca aagcggtaaa acaacaactc aagagttaag atggattcag
    40741 aattttctct taaaagcact cagacaaaca gaaaaagaga ttattaattt attacgagga
    40801 ttagatggca aatatgtggc gagtggcgca tctggtgctc caacgagggg aagaccggag
    40861 gtattaccca caggacggaa tttttactct gtcgatattc gtgctattcc tacagagact
    40921 gcttgggatg tagggagtca agctgcagaa atattaatag aaagatatac acaagaacac
    40981 ggagaatacc ctcaaacatt aggtttatct gtttggggaa cttcaactat gcgaactgga
    41041 ggcgatgata ttgcagaagc tttggcgcta ttaggagtca aacccgtttg ggatggtatt
    41101 tctagaagag ttgtagattt tgaaattttg cccccttcaa ttttaggtcg tccgcgtgta
    41161 gatgtgactt taagagtttc cggttttttc cgcgatgctt tcccaaattt aatggattta
    41221 tttgatagtg ctgtcacggc tgttgctcat ttagatgagc ctgaagatat aaatccttta
    41281 gctgcaaaag tgaaaacaga aacagagttt tggcaaactg aaggattgac agcagaacaa
    41341 gcaaaagcgc gatcgctcta tcgaattttt ggttcaaaac ccagcgctta tggtgctggg
    41401 ttacaaggtt taattgaatc acaaaactgg acaaatgaag atgatttagc tcgtgcttat
    41461 attaattgga gcgcctatgc ttacacccgt aaagctgagg gtaaatttgt accagaagct
    41521 tttacccaaa ggttacacaa tatgcaaatt gttttgcaga accaagataa tcgagagcac
    41581 gatctattag actccgatga ttactatcaa tttcaaggcg gtttaaccgt tgctgttaga
    41641 tcggtgtctg caaaacttcc cgtcacttat tttggcgata attctcgtcc ccaacaacca
    41701 aaaatccgca agcttacaga agaaataact cgcgtttatc gctctagggt tgtgaatcca
    41761 aaatggattg caggagccat gcgtcacggt tataaaggag cctttgaaat ggcagcaact
    41821 ctagattatt tatttgcttt tgatgctacg actaactgtg ttgctgattt tatgtatcaa
    41881 ggaatagctg aggcttattt atttgatgaa acagttcaac aatttattca acaaaataat
    41941 ccttgggtgt tgcgggatat ggcagaaaga ttattagaag ctcaccaacg gggtttgtgg
    42001 gaaaatgtgt caggagaaac tcttgaaaca ttacgttctt tggttcatga agcagaagga
    42061 atcatagaaa gtcagtttta aaaattctct tttaagtagt tacaaactcc cacactcatt
    42121 tgttggaaat taggtgcaat ctgtttccct agtgaatttt caatgacacg ggcgatcgcc
    42181 actgttaact gctgtggtgt accctttatc tgttgtggat cgataataag ttcgcccctg
    42241 ctttggatga gcgttccttt atcatcttca aaaaattgat ttttgccagt acaacgaacg
    42301 gcttcagtaa aaacatgagt attgatgtgc caagtggttg tgtattcaga attattccaa
    42361 atagaatctt ctgtccaatt gagtaaatct tcgctgagga aag
//
