LOCUS       NZ_JHEG04000001        23354 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2433037
            Orig. end                         :: 2456391
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23354
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="10"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..23354
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23354
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13354](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13354
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(1002..1014)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(1221..1955)
                     /locus_tag="HC643_RS09805"
                     /old_locus_tag="DA73_0400009795"
     CDS             complement(1221..1955)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011319491.1"
                     /locus_tag="HC643_RS09805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009795"
                     /product="hypothetical protein"
                     /protein_id="WP_038075821.1"
                     /transl_table=11
                     /translation="MNDSNDRKNFQEIHKDIYTDGNGNTHANVTRTTETVNNGRTDVQS
                     YQNGYLHGQSSERNYQDRIEQRDTDSTGRGIILGLLLTLLTGLTVGAVWYFNQQDSSVE
                     NTTTTPSAVPSTNTASPSPSPVGTQNSQTKTTIIERTREVPTVIERTKEVPVPVFIPAP
                     KPSPATTPNVNITVPPQEGATKPAPPATATTPTSPSNSNTSTSDEETNSDTNTPTSSVE
                     NETVVPSSSPSPEANSQDNPDR"
     misc_feature    complement(2142..2156)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     gene            2557..3396
                     /locus_tag="HC643_RS09810"
                     /old_locus_tag="DA73_0400009800"
     CDS             2557..3396
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (25-185). E-value:
                     9.7e-35. Score: 112.3. Matches aSDomain:
                     nrpspksdomains_HC643_RS09810_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015114588.1"
                     /locus_tag="HC643_RS09810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009800"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_038076090.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-28, bitscore: 99.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.6e-19, bitscore:
                     68.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPVRQTLSTRDIQLSYLEWNQGQEPLLLLHGLADHALVWSSLGD
                     DLAADYHIVAPDMRGHGESSKPEDDYSFESAIADLEALMDKLGWSSAHIVGHSWSGKLA
                     VIWARLNPQRVRSMVLIDPIFIWKIPSIFKLTFPLLYNSLSFLKGMGPFASYEEAEQKA
                     RQLYEFQGWSPLQQQVFKEGIEQKPDGSWGSKFTIAARNGIFEEVMRVPGFTIPIHTPT
                     LFIQPEKGVNRKDWQIKPYKTYLKSLQISTVPGNHWPFLSEPEIFNQTVKAFLQGVR"
     aSDomain        2632..3111
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS09810_Abhydrolase_1.1"
                     /evalue="9.70E-35"
                     /label="HC643_RS09810_Abhydrolase_1.1"
                     /locus_tag="HC643_RS09810"
                     /protein_end="185"
                     /protein_start="25"
                     /score="112.3"
                     /tool="antismash"
                     /translation="PLLLLHGLADHALVWSSLGDDLAADYHIVAPDMRGHGESSKPEDD
                     YSFESAIADLEALMDKLGWSSAHIVGHSWSGKLAVIWARLNPQRVRSMVLIDPIFIWKI
                     PSIFKLTFPLLYNSLSFLKGMGPFASYEEAEQKARQLYEFQGWSPLQQQVFKEGIE"
     gene            3549..5276
                     /locus_tag="HC643_RS09815"
                     /old_locus_tag="DA73_0400009805"
     CDS             3549..5276
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016865995.1"
                     /locus_tag="HC643_RS09815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009805"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_038075823.1"
                     /sec_met_domain="Pkinase (E-value: 7.2e-27, bitscore: 93.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 5e-08, bitscore: 32.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLCINPTCPKPNHPDNDENRFCQSCGSLMELQGRYRVMRLLSDK
                     TGFGKIYEAYERDTPKILKVLKEELSTDAKAVELFQQEVAVLGQLEHSGIPNEDSYFQY
                     QTRHGLNLHCIVMEKIEGPNLEQWLRQQQNRPISQDQAIAWLKQLAEILGLVHGKQYLH
                     RDIKPSNIMIRPDGQLVLIDFGTAREVTRTYLAKLHGSAGGVTAIMSSGYSPPEQLNGL
                     AVPQSDFFALGRTFVFLLTGQNPITLYDAHHNVLHWRDRTVGISPLLLNCVDWLMATEV
                     SQRPANAQEILKRLAAIEQQLGGSAVATVNVVGSLETQPLSPPDTTTLPPKPHVPVQQP
                     SEKVPLLSLFAALLVVLGFLGIVALATRSPQFASLPDYGQAPERKGKVDYFPYEEGRDS
                     QGRIAEFNVAVLSVEYKWLLGSDFQVKYNDQVINLDALRSNLEQEGIQRIMENPTEIIS
                     VGTASCEGVVAVEERRALERSKQIQLLAKKIFSNTNSVKGYRLLNLGQFRRNDCQASQD
                     LTAYQRSIIIIGVRKQSEGVLLDEALRDRLEKKPFADFKLEDYSLGFPEKFKTTPSNL"
     gene            5492..>6474
                     /locus_tag="HC643_RS09820"
                     /old_locus_tag="DA73_0400009810"
     CDS             5492..>6474
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197956.1"
                     /locus_tag="HC643_RS09820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009810"
                     /product="DUF4351 domain-containing protein"
                     /protein_id="WP_167844646.1"
                     /transl_table=11
                     /translation="MTRFIHDKFAKDYLEELLKNYGEVKTSEKVSGEIKEIDVFFIPAQ
                     PQNSDIQTLGLLGRFAEFPMIVEPFRNAASEDEICDCLLKLLEVRASMRREAKANKTKI
                     LKQKIPKLWILTPTASTNRLSSFNINQRPGWLPGIYFLGDALRAAIVVIHQLPPTPETL
                     WLRLLGRGKVQQQAILELVELPENHPYQKATLELVYNLQENLRINQDIDKDDRELIMRL
                     EPLYQRNREQAKEEGRLEGRQEGRLEGRQEGRLEGRQEGRLEGRQEGRLEGRQEGRLEG
                     EQRLVMRQLNRLFGEIDASLTQQIRKLSIEQLEALGEVLLDFSEVA"
     assembly_gap    6475..6540
                     /estimated_length=66
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6541..6636
                     /locus_tag="HC643_RS09825"
                     /old_locus_tag="DA73_0400009815"
     CDS             <6541..6636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017749755.1"
                     /locus_tag="HC643_RS09825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009815"
                     /product="DUF4351 domain-containing protein"
                     /protein_id="WP_167844647.1"
                     /transl_table=11
                     /translation="RKLSIEQLEALGEVLLDFSEVADLQTWLNQS"
     gene            complement(6837..8588)
                     /locus_tag="HC643_RS09830"
                     /old_locus_tag="DA73_0400009820"
     CDS             complement(6837..8588)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016859799.1"
                     /locus_tag="HC643_RS09830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009820"
                     /product="DUF262 domain-containing protein"
                     /protein_id="WP_038075826.1"
                     /transl_table=11
                     /translation="MAIIESRDYTLGELFKDFYVVKAYQREYVWEEKQVGELLEDIYQE
                     FERNKSGTGWEYFIGSIIVCSSDRAYELIDGQQRMTTAYLILCSIRDYREKLKPQETVG
                     SVKELIASSFVDQNGNEVFRDRVELQYDSCDVLKKIAMKEDFDEVPDSSSIKKIKKAYK
                     FILDFFKEKFDEDIQEIKQFYARFTQNVKVVRVETKSVSHALTVFETINNRGIGLDAMD
                     LLKNQMFMHLNSKDFEKLKSKWKKMISLLFKADEKPLRFLRYFITAKYESGERLREDRI
                     YDWFVENKDICGYTENPLEFVDSLVNSAQAFLYFKNGQDKYGHLNRYLLNISYLSTKQH
                     LTLLLASQHLSIELFTELCQEIENFLFVHIVTREGTSRLETLFTQWTGKLRKVSNKIEL
                     EKFILNELQPAKQKLSKQFELAFRQFSKSSIRKKMLQYVLAKLTQYIDEEAYGSIGAYT
                     DLKNYINDTVEIEHILSQTVNKDKSLFDKPAEIEKYIQKLGNLTLLEGSINRSIKNKSF
                     TEKKKAYPKSKFLITKSIAEKVNIGVNTAVDRAVRDLEPFSDWNTESIEKRQELLTQLA
                     KKVWRIV"
     misc_feature    complement(8685..8699)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.98"
                     /tool="antismash"
     gene            complement(9062..9538)
                     /locus_tag="HC643_RS09835"
                     /old_locus_tag="DA73_0400009825"
     CDS             complement(9062..9538)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014608.4"
                     /locus_tag="HC643_RS09835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009825"
                     /product="OsmC family protein"
                     /protein_id="WP_038075828.1"
                     /transl_table=11
                     /translation="MTKFHSYSVAIAWTGNLGEGTANYRAYSRNHEIQSQDKPIIYGSS
                     DPSFRGDPTRYNPEELLLASISACHMLWYLHLCASAKIVVMDYVDRPVGVMEETNNGSG
                     RFTEVTLKPRVAIANSANIETATRLHEEAHKMCFIANSVNFPIRHSAETVAVDN"
     gene            10001..13354
                     /locus_tag="HC643_RS09840"
                     /old_locus_tag="DA73_0400009830"
     CDS             10001..13354
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017749739.1"
                     /locus_tag="HC643_RS09840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009830"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_038075831.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1428.8,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILDFPRLHFQGFARTHAPTGHKNGLVDLSTNTVYMNGERFDRN
                     RPLSEYHEYLQSLGPRFNAEGQWDENGSFSMAKGWDFGGNGHFAIEAKIVSTQREAGQV
                     DQQDPAVGRSIDMWGHFNDYLATTFNRARIFDCDPASNWTTTIMVGQLTFGRQGVSHEV
                     PYMLSAPVEGMQPARWQNFNYIRELPEHPLNGEFKRAEVYQFVIPKDAKDVLWGEETAL
                     SPTVSLLRSAMEREDVLGVVVQFSLSNMSAPLQPDSPVFWHLHGTIGLWCEGELKTYPQ
                     GRLLTPRHIFQNPEDRTLSNLTVAITPQGASLNMVTAVPCNGRAIQAGPGPTHAIASKL
                     DLGELELRTVKSQRLVARIPKEAYQQPAHQLTSGIVDVPLAEPFENLCDEIEHQGLCIV
                     GTHPNGQRQILVREEEINLQVNDACLFVEFPDEKRGLDYSVELEVRSFVRGRPAPVETV
                     YLHQFYNPKGLPQLRYDFDRNPENVGKTFHFPQSLDIVHFKPGKREEMGDFTAKSTIAT
                     DEQGRGWVTVRGVQSGTARVLLSTRADEIPGDPSLTDRAIVSYDNEDRLGFWSGAGSFA
                     VRVLTNDWHLEDIPDESVDFNLIYKHILAFYELSFSFMKAEVFSLADKCKVETYARLMW
                     QMCDPCNKNKTYYMPPTRDMSQPQAMLLRKYLQNQQRVGYVPETKPTPKSTQRTIQTRD
                     ELVAALRHAAELEVAVMLQYVYAAYSIPNYVTGQEYVRRGLWTPEQLRLACGDGQEGHD
                     YGMRGVLLDISREEMVHFLMVNNILMAIGEPFYPAIPNWNEANRRFPIEVDFALEPFGP
                     SSLQRFLQFELPDFLVEDLAHETEPNDPSVDQLHSYGSLSELYRQIRTAIENIPDLIVV
                     KKGCVGGEHHLFLRKDTNKSHPDYQFQVDDVNSALFAIDLIVEQGEGCEVDSPKFEESH
                     YQKFRRIADALAREQTIDATTGHKLPWTPAYPALRNPTLHHKDYSSTVVTVPQTRAVMQ
                     IFNESYYLMMQLMVQHFGLMPHGSMRRSKLMNPAIDVMTGMMRPLGELLMTMPSGKRGK
                     TAGPSFEIAHPPTYIPTPEIAYQAIASRFERLSHQARECEVIPSMVYEMFDFYARYFED
                     FAKNPQHIFG"
     gene            13373..14971
                     /locus_tag="HC643_RS09845"
                     /old_locus_tag="DA73_0400009835"
     CDS             13373..14971
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017307757.1"
                     /locus_tag="HC643_RS09845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009835"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_038075840.1"
                     /transl_table=11
                     /translation="MNNIETDVLIVGGGPVGLSTALELRYQGINCILIEQSDGVVTDPK
                     VSTVGPRSMELYRRWSISQHIRNAGWPVDHTLDVAWVTAVGGYEIYRVPFPSYAERSLP
                     EYTPEPEQVCPQNLVAPVLMDALGQYPSGVIKLLCRLESFEQTDEEVVAKVTNIDSGNT
                     EIIRAKYMVACDGARSIVRKACNVETPSFHPTQLFQSVVFNAPELASQLGSRNAMVFFL
                     VNPKLQEPLRSVDGRGSYRLILKPKENGELRDPEEAVREAIAIDTPIEIVSNLKWYLTH
                     RVADKFRQGRVFFAGDSAHTLSPSGGFGMNTGICDALDLGWKLAATLKGWGGEKLLDTY
                     EMERRPIAVRNLEEANANLQRGQKRAVPPAITSDSPEGEAIRRSMAEGLERSNVKREFD
                     APGVHFGFRYESAIVIPDGTPPNSDPFQWTQNSYPGSRAPHAWLAPDKSILDLFGQGYV
                     LLCFQEQQGTEAFAKACYDRRVPLTITFIEKPEIAQLYEKAYVLVRPDGHVAWRSDTLP
                     SDPGTLIDRVRGYFS"
     gene            14971..15648
                     /locus_tag="HC643_RS09850"
                     /old_locus_tag="DA73_0400009840"
     CDS             14971..15648
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1193: glutathione S-transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017749737.1"
                     /locus_tag="HC643_RS09850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009840"
                     /product="glutathione S-transferase family protein"
                     /protein_id="WP_038076099.1"
                     /sec_met_domain="GST_N_3 (E-value: 4e-18, bitscore: 64.4,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 1.1e-11, bitscore: 43.6,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLYYAPASSYSQRVLIALYEKDAAFTPIEVNLFDKEERSQYTKI
                     NPFAKIPTLVTESGQILFEACIIIEYLDQKFQNKPHLIPQEPKLALEVRMLERIVDAYI
                     NRGREALFSDTQRPVEEQGSSEIKKAHRLLETACLQLEERLSDRTWLAGEEFSLADCAA
                     APTLSYLRMVYSYKHFPQLTNYVRRLESRPSVAKVQNSGREQMIQMLSALKNPLELMPL
                     DNG"
     gene            15892..17142
                     /locus_tag="HC643_RS09855"
                     /old_locus_tag="DA73_0400009845"
     CDS             15892..17142
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317989.1"
                     /locus_tag="HC643_RS09855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009845"
                     /product="cytochrome P450"
                     /protein_id="WP_038084538.1"
                     /sec_met_domain="p450 (E-value: 5e-27, bitscore: 93.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVSTIERLNPFIPEVIADPYAVYRRYREEDPVHWGISANPQLPG
                     AWYIFRYDDVMQVMEDRRFGRETLNEREDVETTPVPTAYNAFLSLVSNWIVFREPPNHT
                     RLKSLASKAFTPKIVENIRPAIYQIADNLLDKVQNRGELDLVEDFAFPLPTKVVAIMLG
                     ADPEDLPLFREWALAMQHASASRLKPPPEVYEQANRGAQSFIDYFTPLIAERRANPRED
                     LISALVKAADEGDKLSDFEIVATCTHLLTAGHETTINLIAKGTLALLHHPEALKKLRSH
                     PEFIPAAVEEFVRYDTPIQMVTRWAYADVEVGGKLIRRGDSVGVMLGSANRDPAQFKNP
                     DVLDIQRQDNKHSAYGGGIHYCLGSSLARAEGQIAINVLLNRLPELRLLDEKIQWANNI
                     VFHGPNHLRVAFNKPVA"
     gene            17419..18684
                     /locus_tag="HC643_RS09860"
                     /old_locus_tag="DA73_0400009850"
     CDS             17419..18684
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317991.1"
                     /locus_tag="HC643_RS09860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009850"
                     /product="cytochrome P450"
                     /protein_id="WP_038084555.1"
                     /sec_met_domain="p450 (E-value: 2.4e-24, bitscore: 84.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEQLSTKPEKKTCPHLGEAYQPFANPQLEEPYSFYKHARVEEPL
                     FYSPLLNGYVLTRYDEILTVLKDPARFSSTDTLSPIVEFTPQVFEVLRQGFPLVRDLVD
                     SDGEEHKRLRAPLMKVFAPERLEAMEDSIRAIANRLVDSFVNDGQADIISQFAYPLPLE
                     AILTMYGIPLDRMAELKQWCYDMNALISSFLTPEEQVQCARSMVAMQHFVAGLIEERRN
                     APCNDLISNVLTSNLNMPELVRILMGLIQAGHKTSSHLIGNALKLLLERPQSWQAICND
                     LSLIPAALEEVLRYDAPVPTMSRTTTQDVELAGVELPKGTRIFLMYASANRDETKYSNS
                     DRFEIERFKQPQAHHLAFGHGVHHCIGSNLARREARIALEILSSRLPNLRLRPNQKFTH
                     VPTMIFRGFTRLEVEWDIPQQR"
     gene            18756..19130
                     /locus_tag="HC643_RS09865"
                     /old_locus_tag="DA73_0400009855"
     CDS             18756..19130
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017749734.1"
                     /locus_tag="HC643_RS09865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009855"
                     /product="VOC family protein"
                     /protein_id="WP_038084540.1"
                     /transl_table=11
                     /translation="MSIVKGLTKIIIYVKDMNTQARFYRDVLNLTAIDPTNVDDYKDVI
                     WVEFATGECSLVLHLDKEKPLGQDRPKLAFSVNDMETAHKMLTERGAKLSDIRSRRPGL
                     KVADGFDPEGNPFSIYYQES"
     misc_feature    complement(18776..18791)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.94"
                     /tool="antismash"
     gene            19299..20615
                     /locus_tag="HC643_RS09870"
                     /old_locus_tag="DA73_0400009860"
     CDS             19299..20615
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017749733.1"
                     /locus_tag="HC643_RS09870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009860"
                     /product="cytochrome P450"
                     /protein_id="WP_082051774.1"
                     /sec_met_domain="p450 (E-value: 2.4e-19, bitscore: 68.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNVDTLQAHNLAFNDQQDEQLSEEKGIEKQQKTCPHLGKEFHPF
                     VNPLLDNPYPFYKHARNEEPIFFSSLLNAYVLTRYEDVLTVLKDPVRFSSAQSLQSVGD
                     FAPETIEVLRQGFPVVSLIGSDGEQHRRFRAPFLKAFATEKLVAMEGSTRAIANRLVDN
                     FINDGQVEILSKFAYPLPLEVIFNMYGVPLNKMAEVKHWGSEVTALFSTPLTPERQVEC
                     ARSYVDLQHFMARLVEERHISPNGDMISDLLTSDLTVPEIVLLLCEMIVAGHKTTANLI
                     GKALKLLLEQPELWQSLCDEPSLIPIALEEVLRYDTPAASMIRVTTQEVSLAGATLPKD
                     TRILLLYGSANRDENQYPDSDRFNIERFKQTPVNHLAFSHGVHHCTGSNLARREGRIAL
                     EVLSSRLPNLRLRPNQQLTHIPALLNRGYAQLYLEWDRA"
     misc_feature    20667..20682
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.86"
                     /tool="antismash"
     misc_feature    20938..20952
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.19"
                     /tool="antismash"
     gene            20977..22620
                     /locus_tag="HC643_RS09875"
                     /old_locus_tag="DA73_0400009865"
     CDS             20977..22620
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017749732.1"
                     /locus_tag="HC643_RS09875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009865"
                     /product="MFS transporter"
                     /protein_id="WP_038084543.1"
                     /transl_table=11
                     /translation="MSSSISPTKIKPASKIYQDKNFYIINAITLIAILGGTIFNPALPT
                     ISKVFSVSSEQVSLVATLFQFPGAIVTPIFGVLADTFGRKQILVPSLLIFALGGTLSGF
                     AQSFRSLLEWRLIQGIGTASLESLQLTIIGDLYRGKQLGSVMAFNAGLIGISSALFPLI
                     GGLLAGFSWRYPFIVSLLAIPIALLVLFTLKLPKQQTNQQNFQLKPYLQSTWSSINNRQ
                     VVGLMFAVMVQFMLQVGACLTYIPILAGNELGASEAFNGFLLTAISLAVAVVASQLGRL
                     TQKFSEIKLIKFSFILAAIAFLIVPFVHNVWLLFIPIVLIGAAQGLAFPSTQALLAGLA
                     AQESRAGFMAVNSTVQSWGQTLGPLLGSIVDMILGTRAVFATSAVISLIALVIFNALLA
                     TKKPSPSPSSDSPSVALSFVNAEQVSFEPSFVEVPTVAEKPVARLFHVQSNKVIELPDN
                     FSLIRIGKPNKRSFPDIDLSGLPNSDIVSRIHAEIKFEGGEYYIQDMGSSNGTYINKYP
                     LLPGIWYKLKPGLTFSIGRRDAVSFKFQIA"
ORIGIN
        1 aacggttgct ttccagggcg gaacgattca atcagccaag tttcttccat ccgtaactgt
       61 gaaattagtc cagcaaacac tacagaagac tttccactac cacttggacc cattactgcg
      121 actaagggct gtttgcgagt agcctgaact aagcactcaa caaatgtctc ttgcccaaaa
      181 aagaactgtg catcctgctc ctgaaatgca gataatccct gatatgggtt tggtgggaga
      241 attacttctg gttcaatctc aattgagaca ggatgaatta gttttttttt aagcactggg
      301 gtctgatgct ctttaagacc aactagctga gagcagccta gctcaaaagc aaactccact
      361 tcttccccgg ctcctagggc atcgtaaaac gctacggcaa aattaatggc tgctttatcc
      421 ccaattgctt gattcatgcc aatcacatag ttaatgtgtt gactaattgc ctccgcctgt
      481 acttctgagt agcaagcatt caacagtaca cactctactc cctttacggc aaacagctta
      541 aacatactag agagtgcatc tgcccgcaca aaggctgcct gccccgtttc atcctccaag
      601 acaataccat cttcgccacc accatgtccg cagaagtgaa caatctgcgg ttgactgtcc
      661 aatattgctc ggtaaaaatc ccgcgagcgc accgcccact tctgctctag cttgaaacgc
      721 tctcgcttgt ttgctcgtcg caatccttca tcaatttccg atacctcttt atctagtcgt
      781 aaccgagaag tatttgtggg attaacagct aataccagaa ttgttttgac acgcgtgttg
      841 ttactcataa gagtacactt aataagtcca agtggtcaat attcttaatt tcaatatctt
      901 tgacattaaa catgatggta aaatatttca agcaacactc tgaaaatttt gacactttga
      961 ctgtgttacc catcagcccc tcagaaactt atctcacaat tttgtaaaac gcaagctgca
     1021 caacaagtaa agatacagcg ctttgcatct gaatgaggta cacccccctt tcatcccccc
     1081 gatgctttgg ggggacagag gggggtaatt tttgtacctc accaagttga aatctgctgt
     1141 atgctgacac gtaaaatagg cgatcgcact caatcatcat agagtgcgat cgccatacta
     1201 gaatattctc cccacagatc ttatcggtct ggattatcct ggctattagc ttcaggagag
     1261 gggctgctac ttggtactac agtttcattt tctacagatg aagtaggtgt attagtatca
     1321 ctatttgttt cttcatcaga agtacttgtg ttggagtttg aaggtgatgt gggtgtagtt
     1381 gctgttgcgg gaggagctgg tttggttgca ccttcttgag gtggaacagt tatgttgaca
     1441 ttaggtgtag tagctggtga tggctttggt gcgggtataa agactggaac tggaacttcc
     1501 ttggttcttt caataactgt tggaacttct ctcgttcttt caataatcgt agttttggtt
     1561 tgagaatttt gagttcccac gggtgatgga cttggagatg cagtgtttgt tgaaggaact
     1621 gctgatggtg tggtagtagt attctctaca gaagaatctt gttgattgaa ataccaaaca
     1681 gcgcctactg ttagccctgt cagtagggtc agtaataagc ctaaaatgat tccacgccca
     1741 gtactatcgg tgtcccgttg ttcaatccga tcttgataat tccgttctga ggattgaccg
     1801 tggaggtaac cattttgata agactgaaca tcggttctac cgttattgac tgtttcagtt
     1861 gttcgtgtca cgttggcgtg agtgtttcca ttcccatcgg tataaatatc tttgtgaatt
     1921 tcttgaaagt ttttgcgatc gtttgagtcg ttcataacag ttgtttttat tctcttaata
     1981 aggtgatagg gaaaaaatga ttggctatga gcaagtcatt aacctgctct caattcttat
     2041 tttgaattga ggaatattat cgatataatt ccctggttat aagtgacaaa tttcattcaa
     2101 agtattatta gaatagcctc actctttacg aaaagctttc tatcgaaaga agtgatatca
     2161 gcttctatca aaggagcgat tgtttcactt taaaagtaga aaattagaga ataagaataa
     2221 atgtctttaa ggtttaattc aattcaacca atcccggtat gactactgta cttacaattt
     2281 tttataaata atctagttgt tcgtatgact ggtacaaaac ggcgctcagt atgaaggcta
     2341 aaggatgaca gcaacacgct tatactctaa gctttatcaa gattgacaat ggtaacagat
     2401 taaaaaagtt tttcctgtac gcttttgcgc ctgaggctct ctacatccgg acttttgcct
     2461 ttttgtatga gctaagcgag cagaaaaagt tgaccgaata taacagaata ttaagcaatg
     2521 aagagaaata ccgtctcaaa atgtggtgaa tttgccatga agcctgtacg tcaaactttg
     2581 tcaacgagag atatccaact ttcttacttg gaatggaacc aaggtcaaga accattactg
     2641 ctgttacacg gtttagccga ccatgcctta gtttggtcta gcttgggaga tgacctagca
     2701 gcagattacc atatcgttgc gccagatatg cgcggtcatg gggaaagtag caaacccgaa
     2761 gatgactaca gttttgagag tgcgatcgcg gacttagaag cactcatgga taaactagga
     2821 tggtcatctg ctcatattgt aggtcattct tggtcgggaa aactggctgt gatttgggca
     2881 agactcaatc cccaacgtgt acggagcatg gttttaatag acccaatttt tatctggaaa
     2941 atccccagta ttttcaaact cacttttcca cttttgtaca attctttatc ctttcttaaa
     3001 gggatgggac cgtttgcaag ttacgaagaa gccgaacaga aagcgcgtca gttatatgaa
     3061 ttccaaggat ggagcccctt acaacagcag gtttttaaag aaggtataga acaaaaaccg
     3121 gatggtagct ggggtagtaa atttacaatc gcagcccgta atggaatttt tgaagaagtg
     3181 atgcgagttc ctggttttac aatcccaatt catactccca ccctgtttat acaaccagaa
     3241 aaaggagtta accgcaaaga ttggcagatc aaaccctaca aaacttatct gaaaagttta
     3301 cagataagta cggttcctgg caatcattgg ccgttcctga gtgaacctga gatatttaat
     3361 caaactgtaa aagcgttttt acagggagtt agataattat ctcacgcact tgttgcaaag
     3421 acgcaaagag tttcttcgcg tctttgcgtg agatattgca actttaatta cgtgtatctg
     3481 tcatttatac aagtaaattt cagtcgctac tatagagtac tggtacgctt acccattcat
     3541 tgtttgtcat gagcctgtgt ataaacccca cgtgtcccaa accgaaccat ccagataatg
     3601 atgaaaaccg cttttgtcaa agctgtggtt ccctcatgga attgcaggga cgttatcggg
     3661 tgatgcggct tttaagtgat aaaacgggtt ttggaaaaat ttatgaggct tacgaacggg
     3721 acacgccaaa aattctgaag gttcttaaag aggaattatc aacggacgcc aaagcagtag
     3781 aacttttcca gcaagaggtg gctgtcttgg gacaattgga acattctggc attcccaatg
     3841 aagatagcta ctttcagtat caaaccagac acggtttgaa tttacactgc attgttatgg
     3901 aaaagattga gggtcctaac ttagaacagt ggctgagaca acagcaaaat agacccattt
     3961 ctcaagacca agccatcgct tggttgaaac aattggccga aattttgggg ctcgtacatg
     4021 gaaagcagta tctgcaccga gatattaagc catctaatat tatgattcga ccggatggac
     4081 agttggtact cattgacttt ggcactgctc gggaagtgac gagaacttac ttagcaaaac
     4141 tacacggtag tgcagggggt gtcacagcta ttatgtcttc cggttatagc cccccagaac
     4201 aattgaatgg attggctgta cctcaatcag atttttttgc tttgggacgc acttttgtat
     4261 ttttgctgac aggacaaaac cccataacat tgtatgacgc ccatcacaac gtattgcatt
     4321 ggcgcgatcg cactgttggt atttcaccac tcctgttaaa ctgtgttgat tggttaatgg
     4381 caacagaagt tagtcaacgt cctgctaatg ctcaagaaat cttaaaacgc cttgctgcga
     4441 tcgaacaaca gttgggagga agtgctgtag ctactgtcaa tgttgtggga agtttagaga
     4501 cacaaccttt gtcaccacca gatacgacaa ccttaccacc aaaaccccat gtcccagtac
     4561 aacagccatc cgaaaaagtg ccattacttt ccttgtttgc agctctattg gtggttttag
     4621 gctttcttgg tatcgttgct ttagcaacac ggtctccaca atttgcttca cttcccgatt
     4681 acggacaagc accagaaaga aaaggaaaag ttgactactt tccctatgaa gaaggtagag
     4741 atagccaagg tagaatagct gaatttaacg tagctgttct ctctgtagaa tataaatggc
     4801 tgttgggtag tgatttccaa gtcaaataca acgaccaagt cattaatcta gatgctttga
     4861 gatccaattt agagcaagaa ggtatacaga gaattatgga aaatcctaca gagattattt
     4921 ctgtaggaac agcttcttgt gagggggtcg tagcagttga agaacgtagg gcgcttgagc
     4981 gttcaaagca gatacaactt ttagctaaaa aaatatttag taatacgaac agtgtcaaag
     5041 gttatcgctt actcaattta gggcaatttc gtcgcaatga ctgtcaggcg agccaggatt
     5101 taaccgctta tcaaagaagc attattatca tcggagttag aaaacaatca gaaggcgttc
     5161 ttttggatga agcccttaga gataggttag agaaaaaacc atttgctgac tttaagttag
     5221 aagattattc tctagggttt ccagagaaat ttaaaacaac acccagtaat ttatagttaa
     5281 tatcaagcct ttttaaagat gcatagaatg agcctgcgaa gcgacctctt tgtttgtgca
     5341 gatccaggct tatagcctga aggcaatatt atgtaacctt acacaaaact aacattagag
     5401 acataataat tttaaatgga gaaagagata tttggataaa gtctgataca atgaccgctt
     5461 aataaatgcc aaaatccatg cttcaaattc catgacccgc tttatacatg ataagtttgc
     5521 aaaagattac cttgaagaat tactcaaaaa ttacggggag gtcaaaacct cagaaaaagt
     5581 ttcaggagag atcaaagaaa ttgatgtttt cttcatcccc gctcaacccc agaattctga
     5641 tatacaaaca ttaggcttgc tgggcagatt tgctgaattt ccgatgatag tagaaccatt
     5701 tcgcaatgca gcctctgaag atgaaatctg cgactgcttg ctaaaattat tggaagtcag
     5761 agcgtccatg cgacgagaag caaaagccaa taaaactaaa attctaaaac agaaaattcc
     5821 caaattgtgg attctcactc ccacagcatc tactaacaga ttatccagct ttaatattaa
     5881 ccaaagaccg ggatggttac caggaattta ctttttggga gatgcgttga gagcagcaat
     5941 tgtggttata catcagctac caccaacacc agagacgcta tggttacgac tgttaggtag
     6001 gggaaaagtg cagcagcaag caattcttga actcgtggag ttaccagaga atcatcccta
     6061 tcaaaaagca acgctagaat tagtttataa cttgcaagaa aatttgagaa tcaatcaaga
     6121 tatagataaa gacgacaggg agttaattat gcgattagag ccgctttatc aacgcaatcg
     6181 agaacaagca aaagaagagg gacggcttga aggacgacaa gagggacgac ttgaaggacg
     6241 acaagaggga cgacttgaag gacgacaaga gggacgactt gaaggacgac aagagggacg
     6301 acttgaagga cgacaagagg gacgacttga aggagagcaa cgtctggtta tgcgtcagct
     6361 aaatcgcctt tttggtgaaa tcgatgcatc attaactcaa caaattagaa aattatctat
     6421 agaacaactt gaagcattgg gagaagtctt attagacttt tctgaagtgg ctgannnnnn
     6481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6541 agaaaattat ctatagaaca acttgaagca ttgggagaag tcttattaga cttttctgaa
     6601 gtggctgatt tacaaacttg gttaaatcaa tcttaagaat acaaaccctt agacctccgc
     6661 tttcttcaag cgggtaactg agttgacaac ctgtcagaaa atttgagaat caatcaagat
     6721 acaaataaag acaatcgcga attgctgtat gcaattagaa ctagtttatc agcccaatag
     6781 agaacaagct aaggaagagg gcgacttgaa caaggacttg aaagaaatta tttcatttac
     6841 acaatgcgcc aaactttttt cgccaattga gttagtaatt cctggcgttt ttcaatagat
     6901 tcagtattcc agtcactaaa tggctctaaa tctcttaccg cacgatcgac agctgtatta
     6961 acaccaatgt ttactttctc tgctatagat ttggtaatta aaaacttcga tttagggtaa
     7021 gctttctttt tttctgtaaa tgatttattt tttattgagc gattaattga tccttcaagt
     7081 aatgtaagat ttccaagttt ttgaatatat ttttcaattt cagcaggttt atcaaataaa
     7141 gatttatcct tattaactgt ttgagataaa atatgttcta tttctactgt atcattaata
     7201 taattcttta aatcagtata agctccaata cttccgtatg cttcttcatc aatatactgc
     7261 gttaattttg ctaaaacgta ttgcaacatt ttctttctaa tagaagattt actgaactga
     7321 cggaaggcta gctcaaactg tttagatagt ttttgtttag caggttgaag ctcgttgagt
     7381 ataaattttt ctagctctat tttattagag accttacgta gctttccagt ccactgagtg
     7441 aataaggttt cgagcctgct agtaccctct cgtgtaacta tatgaacaaa taaaaaattt
     7501 tctatttctt gacataattc tgtaaaaagt tctattgata aatgctgaga tgctaatagt
     7561 aatgtcaaat gttgtttggt agaaaggtaa gatatattta acaaataacg atttagatga
     7621 ccatatttat cttgtccatt tttaaagtat aaaaaagctt gagcagaatt aacaaggcta
     7681 tcaacgaatt ccaaagggtt ttctgtatac ccgcatatat ctttattttc aacaaaccaa
     7741 tcatatattc tatcttctct aagccgttcg cctgactcat attttgcagt tataaagtaa
     7801 cgaagaaagc gtaaaggctt ttcatcagct ttaaatagta agctaatcat ttttttccat
     7861 ttacttttta atttctcaaa atccttacta tttaagtgca taaacatttg gttttttagc
     7921 aaatccattg catccaaacc tattccacgg ttgttaattg tttcaaaaac tgtaagtgca
     7981 tgggatacac tttttgtttc tacacgaaca acctttacat tttgagtgaa gcgagcataa
     8041 aactgtttaa tttcttggat atcttcgtca aatttttctt taaaaaaatc tagaataaat
     8101 ttataagctt ttttaatttt tttgatagaa ctagaatctg gaacttcatc aaaatcttct
     8161 ttcattgcaa tttttttcaa aacatcacaa ctatcatatt gaagttccac tctatctcga
     8221 aatacttcat ttccattttg atccacaaat gaagaggcaa ttaactcttt caccgaacca
     8281 acagtttctt gtggtttgag cttttctcga taatctctta tagaacagag aattaagtat
     8341 gcagttgtca ttcgctgctg tccatcaatt aattcataag ctctatctga actgcacaca
     8401 ataatactgc ctataaaata ctcccatcct gtaccggatt tgtttctctc aaattcttga
     8461 taaatatctt caagaagctc tccaacttgt ttttcttccc aaacatactc ccgctgataa
     8521 gctttaacta cataaaaatc tttaaagagt tctcccaaag tatagtcacg agattcaatt
     8581 atcgccattt ctgtatcctg aaaaataaaa agttatgttt tataaaatca agaatgttaa
     8641 acagtgaata tgaattgtat gctacatact gataaaatat ataaaattta ctaaaaattt
     8701 acgtaattct catatcttaa aaaacgatag ctatgccaaa agaagttctt aactgaacta
     8761 ggagcttggt ttactgcctc aattaataag attctggcat gaatttaaga aaattgggaa
     8821 aaaaagtaat ttgagactta taccaatttt ctatgaagat gcatacaatt agcctgcgaa
     8881 gcgccccctt tgtttgtata gccccaccct tctagaatga gggcaataat gtgcaacttc
     8941 acatagaatt ggtattagtt tattgaattg gataaactgc gatcgctcca ttcccgttac
     9001 aaaacttatt ctcttaactg cgagcttgct ccaacccatt caccattaat acgatggacg
     9061 actagttatc aactgcaaca gtttcagcag agtgacgtat tgggaaattg acagaattag
     9121 caataaagca cattttatga gcttcttcgt gcaaacgggt tgctgtttcg atgtttgcgc
     9181 tgttagcgat cgccacacga ggtttgagtg taacctcagt aaatcgtccg cttccattat
     9241 ttgtctcttc catgacacca actggacgat cgacgtaatc catgacaacg atttttgcac
     9301 tagcacacaa atgaagatac cagagcatgt gacaagcaga aattgatgcc aacagcagtt
     9361 cctctggatt ataccgtgtt gggtcaccac gaaaagatgg gtcagacgag ccataaatta
     9421 taggtttgtc ttgactttga atctcgtggt tgcggctgta tgctcggtaa tttgctgttc
     9481 cttccccaag attaccagtc caagcgatcg caaccgagta actgtgaaat tttgtcataa
     9541 ggtcagaaaa agtcagaaaa ggtaggaaat agtcttaaga tgcttgcagg ggctgcaaca
     9601 tttgcggaac acgggaaaca actcttgatg acaagttata gaaaaacaac gagagactct
     9661 gttctccccc atggtaacca attgactgca agcaaacggt aaataatacc ttatctacca
     9721 aaaggaaata ttaatttatg ttaatcagtc aacatcacct attttttaaa cctaatttta
     9781 aaatgactga aacgattgaa aacaaaattt atctcaagaa tataacaaac agtaacaatt
     9841 ttgaggcttc tattaacaat ttgccaaagt ttatcaaaat tcaaatcttt taaattttta
     9901 gattgagcgg gattggtaag acaaaccagg gaatgaaaag atttctttcc tttgccccta
     9961 acccctgaac cttcgcggaa gaatcaaaga aaaggttatt atgagcatct tagactttcc
    10021 acgcttgcac tttcaaggct ttgcccgcac ccacgccccc acgggacata aaaacggttt
    10081 ggtagatctg agtaccaaca cagtttatat gaatggcgaa cgtttcgatc gcaaccgtcc
    10141 tttatctgaa taccacgaat atcttcaaag cttgggacct cggtttaatg ctgaaggaca
    10201 atgggatgaa aacggttctt tcagtatggc aaagggatgg gattttggcg gaaacggtca
    10261 ctttgcgatc gaagcaaaaa ttgtcagtac ccaacgcgaa gcaggacaag ttgaccagca
    10321 agatccagcg gtcggacgca gcattgatat gtggggacac ttcaatgatt acttagccac
    10381 aactttcaat cgcgcccgga tctttgattg cgatcctgct tccaattgga caaccacaat
    10441 tatggtcggt caactgactt ttggaagaca gggtgtatcc catgaagtcc catatatgct
    10501 ctctgctcct gttgaaggga tgcaacccgc tcgctggcaa aactttaact acattcgaga
    10561 attgccagaa catcccttga acggtgagtt taagcgtgca gaagtctatc aattcgtcat
    10621 acccaaagac gccaaagatg tgctttgggg tgaagaaaca gcactttcac caaccgtttc
    10681 cctattacgt tctgcaatgg agcgagaaga tgtgttggga gtggttgtac agtttagctt
    10741 aagcaatatg tcggctccgt tacaacccga ctcaccagtt ttttggcatt tacatggaac
    10801 tatcggtttg tggtgtgaag gtgaactgaa gacttaccca caaggtcggt tgttaactcc
    10861 ccgtcatatc tttcaaaatc cggaagacag aacgctgtct aacctgacag ttgctattac
    10921 ccctcaaggc gctagcttga atatggtgac agcagtccct tgcaacggac gtgcaattca
    10981 agcaggaccg ggacctactc atgcgatcgc ttccaagctt gacttgggtg agttggaact
    11041 gcgtacagta aaaagccagc gattggtagc acgcattccc aaggaagcat accaacaacc
    11101 agcacatcaa ctgacaagtg gaattgtaga cgtaccttta gcagaaccct ttgaaaatct
    11161 gtgtgatgag atcgaacatc agggcttgtg tattgttgga acacatccca acggtcagcg
    11221 acagatttta gttcgggaag aggaaattaa tctccaagtt aatgatgctt gcttgtttgt
    11281 tgaatttcca gatgaaaagc gtgggttaga ctactctgta gaattagagg tgaggtcttt
    11341 tgtccggggt cgtcccgcac ctgtggaaac agtctacttg caccaatttt acaatcctaa
    11401 aggtttgccg cagttacgct atgacttcga tcgcaatcca gagaatgtcg ggaaaacttt
    11461 ccactttccc caaagtctag acatcgtaca tttcaaaccc ggtaagcgtg aggaaatggg
    11521 cgattttact gctaaaagta ctatcgcaac tgatgaacaa ggacgcggtt gggtgactgt
    11581 gcggggagtt caatcgggga ctgcaagggt actgctatca acacgggctg acgaaatacc
    11641 gggcgatcct tcacttacag accgagcgat cgttagctac gataacgaag atcgccttgg
    11701 cttctggtct ggggctggtt ccttcgccgt tcgagtcttg actaacgatt ggcacttaga
    11761 agacattcca gatgagtcag tagacttcaa cctcatttac aaacatatcc tagctttcta
    11821 cgaactttcc ttttccttca tgaaagccga ggtcttcagt ttagcggaca aatgcaaggt
    11881 cgaaacttac gctcgcctca tgtggcaaat gtgcgaccct tgcaacaaaa acaaaactta
    11941 ttatatgcca cccacacgag atatgtccca acctcaagca atgcttttgc gtaaatattt
    12001 gcaaaaccaa cagcgagtgg gctatgttcc cgaaaccaag ccaacaccaa agagcactca
    12061 acgcaccatt caaactcgcg atgaactcgt agccgccctg cgacacgctg cagaacttga
    12121 ggttgcagtg atgttgcagt atgtctacgc agcatactcc attcccaact atgtcacggg
    12181 tcaagagtac gtgcgtcggg gcttgtggac tcccgaacaa ctgcgtctgg cttgcggtga
    12241 cggtcaggag ggacacgact atggaatgcg gggcgtgttg ttggatatct cccgtgaaga
    12301 aatggttcat ttcttgatgg ttaacaatat attaatggcg attggcgaac ctttttatcc
    12361 agctataccc aattggaatg aagcgaatcg acgcttccca attgaagtgg actttgctct
    12421 agaacccttt ggtccatcta gcttgcaacg attcttacaa tttgaattgc ctgacttttt
    12481 agttgaagat ttagctcatg aaactgaacc caacgatcct agcgttgatc agctgcatag
    12541 ttatggttcg ttgagcgaac tgtatcgcca aattcgtact gcgatcgaaa atattccaga
    12601 tttaattgtt gttaaaaagg gttgcgttgg tggcgaacac cacctattct tacgaaaaga
    12661 tactaataaa tctcatcccg attatcagtt ccaagtagac gacgtcaaca gtgctctctt
    12721 tgccattgac ttaattgtcg aacagggaga aggttgtgag gtggattcac ctaagtttga
    12781 agaatctcat taccaaaaat tccggcgcat tgcagatgca ctggctcgcg aacaaaccat
    12841 tgatgcgact accgggcata aattaccttg gactccagca tatcccgcgt tgcgtaaccc
    12901 cacgctccat cacaaagatt acagttctac tgttgtgact gttccccaaa ccagggccgt
    12961 gatgcaaatt tttaacgagt cttactattt aatgatgcaa ctgatggtgc agcacttcgg
    13021 gttaatgcct catggtagta tgcggcgatc gaagctgatg aatccagcta ttgatgtgat
    13081 gacaggtatg atgcgtccct tgggtgaact gctgatgact atgccttctg ggaaacgcgg
    13141 gaaaacagct ggtccttctt ttgagattgc ccacccacct acatacattc ccacaccaga
    13201 gattgcatat caagcgatcg caagtcgatt tgaacgcctg agtcatcaag caagagaatg
    13261 cgaagtcatc cccagcatgg tttacgaaat gtttgatttc tacgcgagat attttgagga
    13321 ttttgcaaaa aatccccagc acatattcgg ttaataaact tagggaaaag ttatgaataa
    13381 tattgaaaca gatgttctta ttgttggcgg cggaccagtc gggttatcaa cagcacttga
    13441 attgcgttac caaggtatca attgtatcct catagagcaa tccgatggag ttgtcactga
    13501 ccctaaagtt agcacggtag gaccccgctc tatggagctt taccgacgat ggagtatctc
    13561 tcagcacata cgcaatgctg gatggcctgt cgatcatact ttagatgttg catgggtaac
    13621 ggcagtagga ggttatgaaa tataccgcgt accttttcca tcttatgctg agagaagcct
    13681 acctgaatac acgccagaac cagagcaagt ttgccctcaa aatttggtcg cacccgttct
    13741 gatggatgct ttgggacaat atccatcagg agttattaaa cttctttgtc gtttggaaag
    13801 ctttgaacaa acggatgaag aagttgtcgc taaggtgaca aacatagatt caggaaacac
    13861 ggaaatcatt cgtgctaagt atatggtggc ttgcgatggt gctcgcagta tagtccgtaa
    13921 agcttgtaac gttgaaactc catcattcca tcccactcaa ctgtttcaaa gcgttgtctt
    13981 taacgcacca gagctagcaa gtcaattggg ctcgcgcaat gctatggttt tcttcctggt
    14041 taaccccaag ttacaagaac cactccgctc tgtcgatgga cggggatcgt accgtctcat
    14101 tctgaaacca aaagaaaacg gtgagttgcg cgacccagaa gaagctgttc gagaagcgat
    14161 cgcgatcgat acccccattg aaattgtttc caatctcaaa tggtatctca cccatcgcgt
    14221 tgctgacaaa ttccgccaag ggcgcgtgtt ctttgcaggc gattctgctc atacactctc
    14281 accttctggt ggttttggca tgaacacggg gatatgtgat gcactcgacc tgggttggaa
    14341 actagctgct accctcaaag gttggggcgg agaaaaattg ctcgatacct atgagatgga
    14401 aagacgtcct attgcagtcc gaaacctcga agaagcaaat gctaacctcc aacgcggtca
    14461 aaaacgtgct gttcccccag caattacaag cgattctccc gaaggcgaag caattcggag
    14521 atccatggct gaaggtttag agcgcagtaa cgttaagcgc gaattcgacg caccaggggt
    14581 tcattttgga ttccgttacg agtcagcgat cgttatccct gatggtacgc ctcctaacag
    14641 cgatcctttc caatggactc aaaatagtta tcccggatcg cgagcacccc atgcatggtt
    14701 agcacctgac aaatctatat tggatctttt tggtcaaggg tatgtgctgc tgtgcttcca
    14761 agaacaacaa ggaaccgaag cttttgccaa agcttgctac gacagacgcg ttccactgac
    14821 aatcaccttt atcgaaaaac cggaaattgc ccaactttat gaaaaagctt atgtactcgt
    14881 gcgaccagac ggacatgttg cttggagaag cgatacttta ccgagcgatc caggtactct
    14941 tatcgatcgc gtccgaggct acttttcatg atgaaactct actatgcccc agcctcatcc
    15001 tactcccagc gagtcctcat cgctctttat gaaaaagacg cagcttttac acctatagaa
    15061 gttaatcttt ttgacaaaga agagcgatcg caatatacaa aaattaatcc ttttgccaaa
    15121 atccccacgt tagtaaccga atccggtcaa atactatttg aagcttgcat cattatcgag
    15181 tatctcgacc aaaagtttca gaacaaaccc catctcatcc cacaagagcc aaagctagct
    15241 ttagaggtac gaatgctcga acggatcgtt gacgcgtaca tcaaccgagg acgtgaagcg
    15301 ttattttccg acactcagcg tccggtggaa gaacaaggca gtagtgagat aaaaaaagca
    15361 catcgattac tagagacagc gtgcttgcaa ctagaagaac gattgtctga tagaacttgg
    15421 ttggctgggg aagagttttc ccttgcagac tgtgcggctg cacccacctt aagttacctg
    15481 cgtatggttt acagctacaa gcatttccct caattaacaa attacgttcg gcgtttggaa
    15541 tccagaccat ctgtggcaaa agttcaaaac tccggacgag agcaaatgat acaaatgctg
    15601 tctgcgttaa aaaaccctct tgaattaatg ccattggata atggctaatg gctaatggtg
    15661 agtccagccc tgaaggcggg tttcccgccg taggggactg gtgagaccag ccctgcaggc
    15721 gggtttcccg ccgtagggga ctggcgaacc cgaagggcga acccgaaggg cgaacccgaa
    15781 gggcgaaccc gaagggctaa tggctaatgg taattaacaa ttagcaatta gcaattagca
    15841 attagcaatt aacaattagc aattaacaat taacaactaa cggagccaaa aatgaccgtt
    15901 tctacaattg aaagacttaa cccatttata cctgaagtca tcgcagatcc ctatgcagtc
    15961 tatcggcgct acagagaaga agaccccgtg cattggggaa tttctgcaaa tcctcaattg
    16021 cctggtgctt ggtatatctt ccgttatgac gatgttatgc aagtgatgga agaccgcaga
    16081 tttggtcgcg aaactttgaa cgaacgagag gatgttgaaa ctacgccagt accaacggca
    16141 tataatgcgt tcctctctct ggtaagtaac tggatagttt tccgggaacc acccaatcat
    16201 acacggctaa aatctctagc tagcaaggca ttcaccccaa aaattgtcga aaacattcgt
    16261 ccagccatct accaaattgc agacaatctg ctggataaag ttcaaaaccg tggagaattg
    16321 gatttggttg aggatttcgc tttccctctg ccaaccaagg tagttgctat tatgctgggt
    16381 gctgacccag aagacctacc attgtttcgt gaatgggctc ttgctatgca gcatgccagt
    16441 gcttcccgtt tgaaaccacc accagaagtt tacgaacagg caaaccgtgg tgctcaatca
    16501 tttatcgact attttactcc tctaattgca gagcgacgtg ccaatccacg ggaagatctg
    16561 atctcagctt tggttaaggc tgctgatgaa ggcgacaaat tgagtgactt tgaaatcgtt
    16621 gctacttgta ctcacttgtt gacggcggga catgaaacta caatcaatct gattgctaag
    16681 gggacactgg cgttacttca ccatccagaa gcactcaaaa agttacgctc ccaccccgaa
    16741 tttatccctg cggcagtaga agagttcgtc cgctacgaca cccccatcca gatggtaaca
    16801 cgttgggctt atgcagatgt tgaggttggt gggaagttaa tccggcgcgg ggacagtgta
    16861 ggcgtcatgc ttggctctgc taaccgagat cccgctcaat tcaagaatcc cgatgttcta
    16921 gatatacagc gtcaagacaa caaacacagt gcttatggcg gcggtatcca ttactgtctt
    16981 ggttcgtcgt tagcccgcgc tgagggtcaa attgctataa atgtcctgct caaccgttta
    17041 ccagaacttc gtttgctaga cgagaagatt cagtgggcta acaatatcgt gtttcacggt
    17101 cccaatcatc tcagggttgc ttttaataaa cctgtagctt aaggacgtat cgggttaaat
    17161 agttattgca aaagagcatt tttcactcat agattcccga cttcttgaag aagtcgggaa
    17221 ttttgcatga ggtcataaaa agtcagaaaa ggtctgaact cacgctggag agctatttgg
    17281 tttccgaaaa ctctttagtt cttgatggta attaaacata gatgagattc acttgagatg
    17341 ttacgctccc agccagaact gattctcaaa ggcaatagaa ctattgttgg caatattgta
    17401 atacatataa ggatcgaaat gattgaacaa ctttcaacaa agcctgagaa gaaaacttgc
    17461 ccccatcttg gagaagctta ccaacccttt gctaatccac aattggagga accttattca
    17521 ttttataaac atgcaagagt tgaggagcca ctattttaca gcccgttgtt aaacggctat
    17581 gttcttactc gttatgatga gatcctaact gtattgaaag acccagcacg cttttcttcg
    17641 acagatactc tcagcccgat tgtcgaattt acgcctcagg tgtttgaagt actgcgtcaa
    17701 ggctttccct tggtacgcga tttggttgat agcgatggcg aagaacacaa acgcttacgc
    17761 gctcctttga tgaaagtgtt tgcaccagag cgccttgagg ctatggaaga ttctattcgc
    17821 gctattgcta ataggctggt agatagtttt gtcaatgatg gtcaggcaga catcatatcg
    17881 caatttgctt atcctctgcc tcttgaggct atcctcacta tgtacggtat cccattagat
    17941 aggatggcag aactcaagca gtggtgctat gacatgaatg ctttgatatc gtcttttcta
    18001 acgccagaag aacaggtgca atgcgctcgc agtatggtgg cgatgcagca tttcgttgca
    18061 ggtttaatcg aggaacgacg gaatgcacct tgcaacgact taattagcaa tgtacttacc
    18121 tctaacctga atatgccgga gttggtgaga attttaatgg gcttaataca agcaggacat
    18181 aagacgagct cccatttgat tgggaatgcc ttaaaactcc tactggaacg tccccaatcg
    18241 tggcaggcta tttgtaacga tttatcgctc attcctgctg ctttggaaga agtactcagg
    18301 tacgatgctc cagtcccaac aatgagtcgc acaactaccc aagatgtgga actcgcggga
    18361 gttgaactac ccaaagggac tcgtatcttt ttgatgtatg cttccgctaa ccgcgatgaa
    18421 actaagtaca gtaatagcga tcgctttgag attgaacgtt ttaaacaacc acaagctcac
    18481 catctcgcat ttggtcacgg agtccatcac tgtattggtt caaatttagc tcgtcgcgaa
    18541 gcaagaatcg ctctggaaat cttgtcttcg agattgccaa atctgcgact gcgcccaaac
    18601 caaaaattta cccacgtgcc aacaatgatc ttccgtggtt ttacacgtct cgaagtggag
    18661 tgggatatcc ctcaacaaag gtgaaaccca ttacatatat ctctttcaaa cgtttcttac
    18721 ttcaaataaa tatcacatca taaggagtta atcaaatgag tattgtaaaa ggcttgacaa
    18781 aaattatcat ttatgtaaag gatatgaata cccaagcccg cttttatcgc gatgtactga
    18841 acttgacagc gatcgacccg acgaatgtgg atgactacaa ggatgtaatt tgggtagagt
    18901 ttgccacagg ggaatgcagc ctagtgctcc atctagacaa agagaagcca ctcggtcagg
    18961 atagaccaaa gctcgcattt agcgtcaatg acatggaaac tgctcacaag atgttgactg
    19021 agcgcggtgc aaaattaagt gatattcgtt cccgcagacc tgggttaaaa gtagcggatg
    19081 gttttgaccc agaaggtaac cctttctcga tttactatca agagtcataa aaagacagaa
    19141 aaagtcagaa aaggtctgaa ctcaagctat aaagcgattc cgtttgcgaa aagcactcag
    19201 ccatagctgt taattaacaa tagatgattc acaaggttgc ttcatccttg gtggaaatat
    19261 ttctttctag attttttgta agtttaagag acgaaaaaat ggataacgtt gataccctgc
    19321 aagcacacaa tctagcgttc aatgaccaac aagatgaaca attgagtgag gagaaaggaa
    19381 tagaaaaaca gcaaaagact tgccctcatc ttggaaaaga gtttcacccc tttgttaatc
    19441 cattactgga taacccttat cccttctata agcatgctag aaatgaagaa ccaatctttt
    19501 tcagttcact attgaatgct tatgttctga cgcgatatga agatgtttta acagtactga
    19561 aagatccagt acgattttct tctgcacaaa gtctccaatc tgttggcgac tttgctcctg
    19621 agacaattga agtgttgcgt caaggctttc ccgttgtttc acttattggt agtgatggcg
    19681 aacaacacag gcgcttccgt gctccttttt tgaaagcttt cgccacagaa aaactagtcg
    19741 ctatggaagg ctcaactcgt gcgatcgcta acagattggt agacaatttt atcaatgatg
    19801 gtcaggtaga aatcttatca aagtttgctt atcctctgcc ccttgaagtt atcttcaata
    19861 tgtacggtgt tcctttaaat aagatggcag aagtgaagca ttggggtagt gaagttacag
    19921 ctttgttttc tacaccttta acgccagaac gacaagttga gtgtgctcgc agctatgttg
    19981 atttacagca ttttatggca cgtttagttg aagaacgaca catttcacct aacggcgaca
    20041 tgattagcga tctattaact agtgacttaa ctgtaccaga gatagtgctg cttttatgtg
    20101 agatgattgt agcaggacat aaaacaactg ctaatttaat tggcaaagct ttaaaacttt
    20161 tgttagaaca gcctgagttg tggcaaagcc tctgtgatga accatctctt attcctattg
    20221 cactagaaga ggtattgagg tacgatactc cagctgcatc aatgattcgg gttactacac
    20281 aagaggtttc cctcgccgga gccacattac ctaaggacac gcgcatcctt ttgctgtatg
    20341 gttctgccaa tcgtgatgaa aatcagtatc ctgatagcga tcgcttcaac attgaacgtt
    20401 tcaaacagac acctgttaac catctcgcat ttagtcatgg agttcatcac tgcacgggtt
    20461 ctaatttggc tcgtcgggaa ggacggattg ctctagaagt tttgtcttca cgcctgccaa
    20521 atctccggct tcgtccgaac caacaactaa cacatattcc tgcattgctt aaccgaggtt
    20581 acgcacaact ctatttggag tgggacaggg cttaatgagt ggagtaccgg acttgagcat
    20641 tgtgcgatcg caagttaagc caactcttca cttttatctc acagcgattg ataactttta
    20701 ctaaagtgtt gttactccat acaaagtttc gtactactat aacttttgtc tttgttaata
    20761 actccttata actaagacaa aagttctatt gaatcaatag attttgctaa ttggcaacta
    20821 gaaatatttg ccaaacaatt tgaggaatat atttctctat aataaatata ttgatttttt
    20881 tgagattctt catctcacaa gcacaaaatc gtatttttga ttttccttcc aactcacatt
    20941 ttttagaaaa tctttgcaaa ttaaggaaga aaacggatga gttcttctat aagtccaacc
    21001 aaaatcaaac ctgcaagtaa gatataccag gataaaaact tttacattat taatgcgata
    21061 acacttatag caattttggg tggaacaatt tttaatccag cactaccaac tatatcaaaa
    21121 gtttttagtg tttccagcga acaggtgtca ttggttgcaa cgctctttca attccctggt
    21181 gcgattgtaa ctccaatctt tggagtttta gctgacactt ttggtagaaa gcaaatctta
    21241 gtaccttccc tacttatatt tgctttgggt ggaactttaa gcggctttgc ccaaagcttt
    21301 cgcagtcttt tagaatggag acttatacaa ggtattggta ctgcaagctt agaatcttta
    21361 caactgacta taattggcga tctctacaga ggaaaacagc tgggctctgt tatggcgttt
    21421 aatgctggat taatcggcat aagttccgca ctttttcctc tcattggtgg acttttagct
    21481 ggttttagct ggcggtatcc attcatagta tcattgcttg ccattccgat tgctctgttg
    21541 gtattattca cactcaaact gccaaagcaa caaaccaacc agcaaaattt tcaactaaaa
    21601 ccttatctcc aaagtacctg gagtagcatt aacaaccgcc aagttgtagg gctgatgttt
    21661 gcagtgatgg tacaattcat gctgcaagta ggagcttgct taacttacat tccaattttg
    21721 gcaggaaatg agttaggggc atctgaagct tttaatggtt ttctgctgac tgctatatcg
    21781 cttgctgttg ctgttgttgc ttctcaacta ggacggctga cacagaaatt ttctgaaatt
    21841 aagcttatca aattttcttt tattcttgct gctattgcat tcctgattgt tccctttgtt
    21901 cataacgtat ggctgctatt tatcccgatt gtgttaattg gtgcagccca aggtcttgcg
    21961 tttccatcca cgcaagcgtt gctagcaggg cttgctgcac aagaatctcg agccggtttt
    22021 atggcagtaa attcaacagt acaatcctgg ggacaaacac ttggtccttt gcttggaagc
    22081 attgttgata tgattttagg aacgcgggcg gtttttgcaa ctagtgcggt tatttcatta
    22141 atcgcattag tcattttcaa tgctctgcta gcaactaaaa aaccaagccc cagtccttcg
    22201 tcggatagtc cttcggttgc tctcagcttt gtgaatgcag aacaagttag tttcgagcct
    22261 agctttgttg aagttcccac agttgcagaa aaacctgttg ccagattatt ccatgttcaa
    22321 agcaataaag ttattgaatt acccgataat ttctctctca ttcgcatagg aaaacctaac
    22381 aaacgcagct ttcctgatat cgatttatct ggattaccca attctgatat tgtttctcgg
    22441 attcatgcag aaattaaatt tgagggagga gaatactaca ttcaagatat gggcagttct
    22501 aatggaactt acattaataa atatcctcta ttacccggaa tttggtataa gttaaagccc
    22561 ggtttgacct tcagtatcgg taggcgagat gcagtctctt ttaaatttca aattgcttaa
    22621 tgagttatat cgtgttcgga taatggctta cgattaaaaa ttaagcatgt cgccgcgtat
    22681 cccaatctcc gcgtcattct tatcgtcatt acttaggcga acctggtatt agtggttagt
    22741 ggttagcagg caattattca tgaaattaga ctaacaatgg ataatccaca atcctagcaa
    22801 tgtataaatt cctatcgatt cccgacttct tgaagaagcc gggaattttg tagaaagtca
    22861 gtacccgtga aaattaattt tctcttcatg ttgcctgaaa tacctgtgta atcgtgattc
    22921 taggttctag agatatataa ataaattgac ctagctactc aattgtagac aagagtcata
    22981 aaaagacaga aaaggtctga aaaggtctga acttaagctc cagagctatt taatttgcga
    23041 aaatgcttca attctggatg ttggttaaat acagaagaca atcactgaaa agtatcacca
    23101 acaactacta actactatga aatttcaaca agataaatca aatcctatct ataaagataa
    23161 caatctctat atcatcatca gtataacact gatatcagtt atgggtgtga tggctatcaa
    23221 tccagcacta ccagccattg gggaagcttt taaggttcca gatgaacaaa ttggattggt
    23281 gatggcaagc tttctgatcc caattgcaat tggaactcca atctttggca ttttggctga
    23341 ccgtattggt agaa
//
