LOCUS       NZ_JHEG04000001        22253 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2281937
            Orig. end                         :: 2304190
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22253
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="9"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22253
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22253
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12253](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12253)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(308..2491)
                     /locus_tag="HC643_RS09285"
                     /old_locus_tag="DA73_0400009280"
     CDS             complement(308..2491)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017748903.1"
                     /locus_tag="HC643_RS09285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009280"
                     /product="AAA-like domain-containing protein"
                     /protein_id="WP_038080723.1"
                     /transl_table=11
                     /translation="MTAKILVVDDEPDLELLLRQVFRKKIREKNFQLFFAQNGLQALEK
                     LEAEQDIDIVLTDIYMPEMDGLALLTKLSELYPLVKAVIISAYGDLEKIRTAMNRGAFD
                     FLTKPINFQDLEITTNKTLQHVQRMKAAREQEMFAQKAQAELLTRLQAEVVERQRVEVA
                     LRESEGRLAQFLEAVAVGIFVIDATGQPYYANQTAQRILGKGVEVTTKTPQLPQIYNAY
                     LAGTEQLYPTEQQPIIRALNGETTTVDDLEIRQLDNIIPLEVAATPIYNEKGEVVYAIA
                     AFTDITQRQQAEAERSRFTQELALNNIALQKAKDALAESNRTLEQKVEERTRELSQTLE
                     ILKATQAELEFENALLRSTEDTSGFDYQVGGSLPMDAPTYVVRSSDRYLYKALKRGEFC
                     YILNTRQMGKSSLMVRMLNRLQTEGFACAAIDITRLGVEEVTPVQWYKGLAVELWQNFD
                     LMGKVNLKAWWKEQQDLSPFQCLSRFIEEIVLSQVQSKHIFIFIDEIDTVLGLNFPVND
                     FFALIRFCYNQRSINAKYKRLTFALFGVATPSDLLSDPQRTPFNIGQAIQLNGFQEHEA
                     QPLLQGLAEKVSNPQVLLKELLAWTNGQPFLTQKICHLIRSSCSCVPTNQEAQWIETLV
                     RTQVIENWESQDEPEHLRTIRDRILNSKQNTLRLLALYRQILHSGTVASVDSPEEKELI
                     LSGLAIKQRGCLKVHNRIYELIFNESWITLHGG"
     gene            complement(2515..2874)
                     /locus_tag="HC643_RS09290"
                     /old_locus_tag="DA73_0400009285"
     CDS             complement(2515..2874)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017748904.1"
                     /locus_tag="HC643_RS09290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009285"
                     /product="response regulator"
                     /protein_id="WP_202048707.1"
                     /transl_table=11
                     /translation="MIVDDEQDVKLLFQQKFRRESRQNQITFYFAFSGEEALEQLQNNR
                     TKCLSLVLADINMPGMNGLELLKIIKERFPDLKVFIITAYDDDKNYRAAKKLGADDYIT
                     KPIEFNKLKEKILSL"
     gene            complement(3123..8573)
                     /locus_tag="HC643_RS09295"
                     /old_locus_tag="DA73_0400009290"
     CDS             complement(3123..8573)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017748905.1"
                     /locus_tag="HC643_RS09295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009290"
                     /product="ATP-binding sensor histidine kinase"
                     /protein_id="WP_038080727.1"
                     /sec_met_domain="Pkinase (E-value: 2.6e-35, bitscore:
                     120.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIADYQIISKIYESANSLVYRSVCNSITQPVILKILKEDYPTP
                     SELTRYKQEYEITRSLKIDGVIKAYNLLPYKNTLAMILEDFGGKSLDLVMQSKKFTLPG
                     FLVIAIQIAETLSQIHAANIIHKDINPSNIILNLETGQLKIIDFGISTVFTRENPTIKN
                     PNVLEGTLAYLSPEQTGRMNRVLDYSTDFYSLGATFYKILTQRLPFETNDPLELIHCHI
                     AKQAAPPHEVDSKIPRTLSNIVMKLLAKTSEERYQSALGLKADLEECLIQLQQTGQISE
                     FPIARYDISDRFKISQKLYGRDTEIATLLSRYKHVAESNSLEEQAFQRTGRKQSEMVLV
                     GGYSGIGKSVLVQELYKPITEQRGYFISGKFDQFQRNIPYSAVVSAFKSLVRQLLTESE
                     AQLARWREKLLAAFGVNGQVIVEVISEVEQIVGPQPPVQPLEPTEAQNRFNAVFQNFIR
                     VFCQRSHPLVIFLDDLQWADSASLKLIELMMTDNCLGYLLLLGAYRDNEVSANHPTMLV
                     IERLKQQGAIVNTIILNPLKLEEITQMIADTLHSDREIVKPLAELVYRKTSGNPFFINE
                     FLKTIYQESLLTFERQQKCWYWNISQIESLGITENVVDLMLGKLRKLSKLTQKALRLAA
                     CVGNSFDLTTLSIIYEKSPAETYKSLLSAIQLGLIQPISELETTSDIPIEAELVIQHYK
                     FLHDRVQQAAYALIDGDLKKAVHLQIGKLLLANMSEAEREGKVFTLVDHLNKGRELIEN
                     LAEKESLAEFNLHAGKKAKEATAYTASREYLLLAANEFPGNIWNDRYEMALDLYKELAE
                     VEYLNGNFEKSQSLLDTAIQQAKTPLDRTEYYFLRIIQCTLLGEYSKAIETGRIALKSL
                     GIDLPTQNLQAAFETELVEYRKNLGERDISVLFNNPEMEIPEKRSALKILTRIFPAAWI
                     LDPMLMYLVAAKLVNLNIKYGHMEKSSMGYSFFGVVNTHVLHDYHSGYEYSSLGMKLSD
                     KYRDWSCKSAVTQVHGSFTMHWLKHIKFSERVNNEGAEAGLQVGEFQLVGYTMTYNLYN
                     LICQGKSLNSLQKEASRSLQFSQETQNQWAINCILGATIFMENLMGLTQDKFCFDIKDT
                     SEKCFLEDAQRETLAAICFYYILKTQILYLYGRPIDLTYLEQAGKLVDYIPGTIAIAEH
                     NFYYSLNLAFLYPQASIGERNKYWHQLEINQQYMKQWADNCPENFLHKYILVAAEMSRL
                     SGQWHQAMDLYDQAIESARKNEFTQNEALSNELAAKFWLERGKAEFAQLYMRKAYQGYQ
                     LWGAKRKVEDLEEKYPQLLVSTSLGSKTSRINTTTTSTSASSEVLDLATVLKASQTISG
                     EIVLSKLLQNLMKTVLENAGAEKGFLILDKEGNWLIEAEGVVNDDEVTVLRSIPVDSVD
                     SNSQIPLLSSAIINYVARTQENVILNDASNGGQFIRDRYMIATQPKSILCTPLLYQGKL
                     NGILYLENNLTTGAFTSDRVEILKILSAQAAISIENSRLYEQLEDYSRTLEQKVEVRTH
                     ELQEKNQELASILEKLKATQAQIIAQEKLASLGTLTAGIAHEIKNPLNFVNNFAELSIE
                     LTQELLAEIERQKDQLEPDSKEYIEEILSDLSQNAQKINEHGKRADNIVRGMLMHSRSQ
                     TGDERQMAHANTLLGEAINLAYHGMRAKDSSFYMTVETDYDNNIDRLNIVPQNISRALI
                     NIINNAGYAVHKKAIRFQTRSRSDRETFSPTLSVKTQDLEDVIEITIKDNGDGIPREMQ
                     DRIFHPFFTTKPPGEGTGLGLSIAHDIIVQQHQGVIKVESEVNNFTKFIIVLPKSYSKN
                     R"
     misc_feature    complement(8667..8683)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 25.4"
                     /tool="antismash"
     gene            complement(8894..9976)
                     /locus_tag="HC643_RS09300"
                     /old_locus_tag="DA73_0400009295"
     CDS             complement(8894..9976)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015206709.1"
                     /locus_tag="HC643_RS09300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009295"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_050046245.1"
                     /transl_table=11
                     /translation="MLEGYRIIDADSHVYEPHHMWQDYLEPAFKSFALSPELTLAGEKI
                     VNKYSNRLHQEGAKQVTQAYPLSWLNNFDAESHVRAMQQMGVDISFIYPTYFSWIVAVD
                     TIAPQLAGAFVRAYNNWLRDFCSYNPRILRGVGVVNLHAPEEMVLELQRIAEFGWKSVF
                     LRPNPVKRRVLSDCAYEPFWTKCEELGIAVSLHESTHSRLPSAGADRFNTRFALHACSH
                     PMEQMMALLSLIEGGVLERHPKLRVGFLESGCGWLPYWLWRLDREYEDLRWEVADNVKM
                     KPSEYFRRQCFISMEPSEPYLSQILEYLGSDNLIFGSDYPHMDHHPKVVAEVVALQNQL
                     SKKVVQKILWDNPVRFYNLD"
     gene            complement(10001..12253)
                     /locus_tag="HC643_RS09305"
                     /old_locus_tag="DA73_0400009300"
     CDS             complement(10001..12253)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017748907.1"
                     /locus_tag="HC643_RS09305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009300"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_038080729.1"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 2.2e-23, bitscore:
                     80.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 2.7e-19,
                     bitscore: 67.8, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 7.5e-14,
                     bitscore: 50.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03882 (E-value: 4.6e-49, bitscore:
                     165.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 3.6e-91, bitscore: 305.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 2.9e-81, bitscore:
                     272.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRKPKFKTCFRIEIVETEGVFLISERDTIVLQDSLYQLLCPLLD
                     GSRTVDEIVQQLQDKLPVPYIYYALMELEQKGYLMEHQEVLPSNIAVFCEHLKVKTEDV
                     SRRLQATTVTVKALGNLSVSELIATLESLQIQVVKEGDFEVVLTDDYLRPELVEINQKN
                     LARSRPWMSIKPIGTVIWIGPIFHPEKTGCWECLSQRLQGNRPVEGFIQRRDRVSSPLT
                     PPLADLPTTLKTAITMAATQILQWIVKAENKRLEGILVTHDTLTLETQSHFLIKRPQCH
                     SCGILKQQYLSPLPLILGNRKKTFTADGGHRCVSPEATLERYRYHISPITGVVRDLGKL
                     SFDARGLTHTYFAKHHFASVFDDLSVLEKNIGGRSAGKGRTDAQARASGFCEAIERYSG
                     VFQGEEIRVKSSYRKMNNKAIHPNTCMNFSQAQYDERSVWNAHCGSFFQRVPEPFDEER
                     EIEWTPVWSLTYRDFKYLPTAYCYFGYPMSSQPDCWADTNGCAAGNTLEEAIVQGFMEL
                     VERDSVALWWYNRTQRAAVDLESFEEPYFQALRSYYQSLDREFWVLDITSDLNIPAFAA
                     ISYKSKCQVKDIILGFGAHFDPKLAVQRALTEMNQILPAVLTADANGITQYATSAEPPV
                     LDWWKTATLENQPYLIPDKNAAVKKSFDYSYIENDNFLDDIKLCQQIIEQRGMEMLVLD
                     QTRPDIGLKVVKVIIPGMRHFWKRLAPGRLYDVPVELGWLKEPTPEECLNPIPMWM"
     aSDomain        complement(11975..12247)
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS09305_NHLP_CD_RRE.1"
                     /evalue="7.90E-26"
                     /identifier="RREFam015.1"
                     /label="HC643_RS09305"
                     /locus_tag="HC643_RS09305"
                     /protein_end="93"
                     /protein_start="2"
                     /score="80.9"
                     /tool="antismash"
                     /translation="RKPKFKTCFRIEIVETEGVFLISERDTIVLQDSLYQLLCPLLDGS
                     RTVDEIVQQLQDKLPVPYIYYALMELEQKGYLMEHQEVLPSNIAVF"
     aSDomain        complement(12005..12241)
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS09305_Goadsporin_CD_RRE.1"
                     /evalue="2.70E-16"
                     /identifier="RREFam013.1"
                     /label="HC643_RS09305"
                     /locus_tag="HC643_RS09305"
                     /protein_end="83"
                     /protein_start="4"
                     /score="50.4"
                     /tool="antismash"
                     /translation="PKFKTCFRIEIVETEGVFLISERDTIVLQDSLYQLLCPLLDGSRT
                     VDEIVQQLQDKLPVPYIYYALMELEQKGYLMEHQ"
     aSDomain        complement(12017..12241)
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS09305_Cyanobactin_D_RRE.1"
                     /evalue="9.70E-22"
                     /identifier="RREFam007.1"
                     /label="HC643_RS09305"
                     /locus_tag="HC643_RS09305"
                     /protein_end="79"
                     /protein_start="4"
                     /score="67.8"
                     /tool="antismash"
                     /translation="PKFKTCFRIEIVETEGVFLISERDTIVLQDSLYQLLCPLLDGSRT
                     VDEIVQQLQDKLPVPYIYYALMELEQKGYL"
     gene            complement(12555..13172)
                     /locus_tag="HC643_RS09310"
                     /old_locus_tag="DA73_0400009305"
     CDS             complement(12555..13172)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS09310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400009305"
                     /product="hypothetical protein"
                     /protein_id="WP_038080731.1"
                     /transl_table=11
                     /translation="MAEQSNTTYMTSLPEELQTPENIAKIRIIIKQWTQIIAWTWTTFL
                     AFDGDEDKKRQEQQLKNYFSSILKKQALARLAAIEYGDPPSAQLAEETSKIIKEVIIAN
                     QTAPDIQLTLSDVYRKLTANDYIFTDPLIQDFRFEVVVDSFTGRIRQDDKNQAKYLATI
                     AYPPRPALSEFTVTEEQLNQWVQDNNSGEYLPPSVYIPVSGS"
     gene            complement(13190..14680)
                     /locus_tag="HC643_RS09315"
                     /old_locus_tag="DA73_0400009310"
     CDS             complement(13190..14680)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS09315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400009310"
                     /product="hypothetical protein"
                     /protein_id="WP_038080733.1"
                     /transl_table=11
                     /translation="MRNIQRLIFISIISISVVVLGCVSTGLADTQIDKELQSQSRFQLK
                     PEITSEIPHNPNLAKQQALYPNTPRVAFIDNFAWQVFLALNWPADCQQGEPLRNEKIGE
                     VPNAPRLWEFYRTPETIFLSAGKEPSIQPTKPFTCLNVTSTRGLQTENSRLQLTESEKL
                     DSNGTNANKPLVDQQGNYIIMEAYINPQEFNQIVENKWYDAVNLQQFNNDDKKFALVCS
                     EDANANPLNVPCSTYEKEGAIEIKAAWRVFDPQTSQEEKARYYTTKRQRTIPAQSTECT
                     EGKALCSDTDEEFSQIVEVGLIGFHIKHKTSEQGWIWSTFEQVDNVPDSTSNRARYTLY
                     NPDCRENCQENKPYVEKPYLWRQEVPHAVKKVGDKIENQIPSQIIRPPNSALNAQRLEQ
                     NKQWQDALKEISQSSVWQYYQLIGTQWLTNPSLPYNTSLRDVTPKSPLANVAIEPYIPR
                     SSCIECHTGATLQANRQLFTDFSFPMGRANSSAPSATN"
     gene            complement(15620..17881)
                     /locus_tag="HC643_RS09320"
                     /old_locus_tag="DA73_0400009315"
     CDS             complement(15620..17881)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017748910.1"
                     /locus_tag="HC643_RS09320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009315"
                     /product="AAA-like domain-containing protein"
                     /protein_id="WP_038080737.1"
                     /transl_table=11
                     /translation="MSRLVVLSLGQGNLRDGCATVTAQVGEASNPYHMKISASLPAAPK
                     ILELYQNWQALYYAFYQRLSCWRNSVETDDYLEISEVGLTHVSEADILKLSQKLSKRLN
                     TWLDSKEFRKIDRQLRTQLKPSDEIRFIIETNDPLLRRLPWHLWEFFEDYPYGEVALSA
                     TEYQNTNKLPINHRKYQLKILAIFGNAQGIDISHDRMFLEKLSHRAEIKFLVEPNLRDL
                     NDHLWQEGWDILFFAGHSSSEEKGILQINPTDTISLEKLKYALKEAMGRGLKLAIFNSC
                     DGLGLAQQLEDVNIPQSIVMREAVPDVVAQEFLRYFITEFSSGKSLYAALRSARERLQA
                     LEKEYPCATWLPVIFQNPAESSMVWLQDGVRIEWEDVISSPNSTPSFNLRGMQTETRSP
                     FTTPMLSPSINIHQDLLPPYPSGSVPLDSPYYIENTAVSAQIYREITKPGALIRIKGPM
                     EIGKTSLLSRILEYASCIGYRTIGLNFEEQIDRDILSDLNRFLRWLCANISRQLQIEPR
                     MDEYWDEDIGSKVSCSLYLQNYVLEYIDSPVVLALDEVNQIFEYPQVAKEFLPLLRSWY
                     EEAKRRPIWQKLRLIVVHSTEVYVPLQLHQSPFNVGLPIQLQSFSFEQVQQLALRYGLA
                     WKNGLEATLLMDMVGGHPALVHLALYHLSQQEITLTQLLQNSATPTGIYYHHLQRHWVT
                     LEAQPELASALHKVINTTEAVQLEPVIAYKLSSMGFIKLDNNKATPSCQLYRKYFQSKL
                     "
     misc_feature    complement(18190..18204)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.26"
                     /tool="antismash"
     gene            complement(18203..19576)
                     /locus_tag="HC643_RS09325"
                     /old_locus_tag="DA73_0400009320"
     CDS             complement(18203..19576)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016873880.1"
                     /locus_tag="HC643_RS09325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009320"
                     /product="AAA-like domain-containing protein"
                     /protein_id="WP_038080740.1"
                     /transl_table=11
                     /translation="MTLDSLLAIVNHKLLETQNRPLNDTETLILRGIWQSQTYGQMAQA
                     GGYSPGYLTNVVAPGLCQKLSLIIGRRVTKKNCRALLEFYAAQALPAIATPSRQLSTHF
                     LTNKQKSPRFPSGSVPLDSIYYIQNTAIQEQAFAEISKPGALIRLKAPKEMGKTSVLLR
                     IIEYAKNLGYRTVSLNLEEHLEGEIITDLKRFLRCLCANISLQLGLEPKLDDYWDWDLG
                     SKVSCSLFLRNYVLEQIDSPIVLALDDVDRIFESPQVAKEFFPLLRSWYEEAKRQPIWQ
                     KLRLIVVHSTEVYVPLQLHQSPFNVGLPIQLRHFNLSQVQELSQYYGIDWVDDNEVTFL
                     TDVVGGHPALVHLAVYHLSDGEITLTQLLEDASTPGGIYYHHLQRHWSTLQAQPELASA
                     FERVMQTTIPVLLEPVIAYKLNSMGLIKLENDRAVPSCELYRQYFQRKFSSPILKKLV"
     gene            complement(19905..20990)
                     /locus_tag="HC643_RS09330"
                     /old_locus_tag="DA73_0400009325"
     CDS             complement(19905..20990)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0019808 - polyamine binding [Evidence
                     IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011319086.1"
                     /locus_tag="HC643_RS09330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009325"
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_038080742.1"
                     /transl_table=11
                     /translation="MTNRREFITGIAALSSLSLAGCGWRLGNVRASATTGSRDQMYIYT
                     WEQYTNKDLLKTFSAQTGIKVLADLFDSNEAMLSKIQAGGGSAYSVIYPSDYMVRKMVD
                     LGLLIRLERDRIIGLDNLFPRFQNPIYDPNNRHSIPFSWGTTGFIYNSEKLTTPPENWD
                     YLWENKQVLSKRMALMNDFREVIGAVLKMLGYSYNSTNENEIKQAVDTLKVLIPDVAAF
                     TTDAWRNQIIAGDLLLAMCYSSDAVKIVRENPKLKYVIPKSGSSLWTDTVVIPKTAPNI
                     EAGYAWINLILRPEVASEMSQILVLSTPNRAGFEQLPKKIQNNPNLFPSEAILTKCERL
                     APLGQEVEALYERYWIELTSS"
     gene            complement(20983..22116)
                     /locus_tag="HC643_RS09335"
                     /old_locus_tag="DA73_0400009330"
     CDS             complement(20983..22116)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016952365.1"
                     /locus_tag="HC643_RS09335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400009330"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_038080744.1"
                     /transl_table=11
                     /translation="MAQTLIQNQGGTAGFEPLDVELLSVFKFFNQEPAVHGVDLDIRQG
                     EFFSILGPSGCGKTTTLRLIAGFERADAGQVLIRGQSMTSVPPYRRPVNTVFQSYALFN
                     HLNIWENVAFGLRLKNLRKKEIESRVKQALELVKLEGLRSRFPNQLSGGQQQRIALARA
                     IVNRPAVLLLDEPLGALDLKLRKEMRVELSNLHKELGLTFIMVTHDQEEALSLSDRVAV
                     MNQGKLEQVGTPSEIYEQPQTVFVANFIGDTNLLPGEITGADASHVKILTKTGLSIIVT
                     REENTPTEISQSIVVSVRPEKIQLSLYKPSVENNCFEGRLVNIMYLGTHINYVVQLING
                     LQINVLQPNTFVNLPDRETPIYAWWTEGDCLALVSHD"
     misc_feature    22157..22171
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
ORIGIN
        1 cggatgtagt tgtagagatt tcgagggttg actatttctc caggtctgat atttggtact
       61 aaacttaact caaaaataat aagtgttggc agtactaaca aaagcaacaa ccaaagtcca
      121 gatggtgcaa gcagtatcaa tggttgtagg aagtccaacc aaggacgacg aaattttggg
      181 gctttggcaa tttgatttga ggtttgagtg gtcacaagcc gatcgacaat ttttcacgaa
      241 cttatttagt ttagtctgga agtcagaaaa tagagctact tgcagtgcaa ggaaaagatc
      301 cgatagctca cccaccgtgt aaggtaatcc aactttcatt aaaaattaat tcataaatac
      361 gattgtgaac ttttaagcaa ccccgttgct tgatcgctag ccctgacaag attaattcct
      421 tttcctccgg gctgtccact gaagcaaccg ttccagagtg tagaatttgt cgataaagtg
      481 ctagaaggcg cagagtgttt tgcttgctgt taagaatgcg atcgcgaatt gttcttaaat
      541 gttctggttc atcctgagat tcccaattct ctatcacctg agttcgcacc aaagtttcta
      601 tccattgcgc ttcttgattg gtgggaacgc aagagcaaga agaacggatc agatgacaaa
      661 tcttttgcgt gaggaaaggt tgaccgtttg tccatgctag caattctttt aaaagaactt
      721 gcggattgct aactttctcc gcaagtcctt gtaataaagg ttgggcttca tgctcctgaa
      781 aaccattgag ttgaattgct tgaccaatat taaagggggt tcgttgggga tcgctcagca
      841 aatcagaggg agttgcaact ccaaataaag caaaggttaa tcttttatac ttggcattaa
      901 tgctgcgttg gttgtagcaa aagcgaatta gagcaaaaaa gtcattgact ggaaaattta
      961 aacccaaaac agtatcaatt tcatctataa aaataaaaat atgcttgctt tgaacttgag
     1021 ataatacgat ctcctctata aaccgactca agcactgaaa gggtgacaaa tcctgttgct
     1081 ctttccacca agcttttaaa tttacttttc ccatcaaatc aaaattttgc cacaactcca
     1141 ccgccaatcc cttgtaccat tgaactggag tgacttcttc tacgccaagt cgagtaatgt
     1201 caattgccgc acaagcaaaa ccttcagttt gcaagcggtt cagcatgcgt accataaggc
     1261 ttgacttacc catttgccgg gtgttcagta tgtaacaaaa ctctccacgt tttaacgctt
     1321 tataaagata gcgatctgaa gaacgtacca cataagtggg agcatccatt ggcaaactac
     1381 cgccaacttg ataatcaaaa cctgaggtat cctccgtact tcttaataaa gcattttcaa
     1441 attcaagttc agcttgagta gctttcaaaa tttccaatgt ttgagaaagt tctcttgtgc
     1501 gctcttccac tttttgttct aaagtccgat tagactctgc taaggcatct ttagcctttt
     1561 gcaaagcgat attattcagc gcaagttctt gagtaaatcg agatcgttct gcttctgctt
     1621 gttggcgttg ggtgatgtca gtgaaggcag caatagcata aacaacttca cctttttcgt
     1681 tataaattgg agttgcggct acttctagag gaataatgtt atctaattga cgaatttcaa
     1741 gatcgtcaac agttgtggtt tcaccgttga gcgctcgaat aatgggctgt tgttctgtgg
     1801 ggtatagttg ttcggttcca gcaaggtaag cgttgtatat ttgaggtagt tgaggtgttt
     1861 tggttgtaac ttcaactcct ttccccaaaa ttctttgggc agtttgattg gcgtagtaag
     1921 gctgtccggt ggcatcaatc acaaatatac cgaccgcgac agcttctaaa aattgagcta
     1981 gcctcccctc actttcacgc aaggcaactt ctactcgctg acgttctaca acttcggctt
     2041 gcaggcgagt taatagttct gcttgggctt tttgtgcgaa catttcttgt tctcgcgctg
     2101 ctttcatcct ctgtacgtgt tgtagagttt tgttggtagt aatttctaaa tcttgaaaat
     2161 taattggctt tgtcaggaag tcaaaagccc ctcggttcat cgcggttctg attttttcaa
     2221 gatccccata ggcggagata ataactgctt tgacgagtgg gtacaactcg cttagtttag
     2281 tcagcaaagc aagaccgtcc atttctggca tatagatatc ggttaagaca atatctatat
     2341 cttgttctgc ttccagtttt tctagtgctt gcaaaccatt ttgggcaaaa aataattgaa
     2401 aatttttttc tcgaattttt tttctaaata cctgacgaag taggagttct aaatcgggtt
     2461 cgtcatccac aactaatatt tttgctgtca taattttttc ccaattggga tgttttataa
     2521 actcaagatt ttttccttaa gtttgttaaa ttcaattggt tttgtaatgt aatcatctgc
     2581 gcccaatttt tttgctgctc gataattctt gtcatcatca taagcagtaa ttataaatac
     2641 ttttagatcg ggaaatcttt cttttataat tttgagtagt tctaacccat tcattccagg
     2701 catattaata tctgctagaa ctagagatag acatttagta cgattatttt gtaattgctc
     2761 tagtgcttct tctcctgaga aagcaaaata gaaggtaatt tggttttgtc tgctttccct
     2821 cctaaatttt tgctgaaata gcagttttac atcttgttcg tcgtctacaa tcattatttt
     2881 catctatgac ttaaatcatt gactaaatga gcaaaatatg tagagattaa aaactaagtt
     2941 tcctaaactc tcttacatta ttttatgggg aaacaaagat tctggtctgc aaagatcggg
     3001 ctagtgccaa tctcttcata gaaaatgtat aaaaatgcta aattatttgt aaaaaatttt
     3061 aagtagtgtg ggtatcggtc atcctacaag gtttttggag ggctttatcc atcgtactta
     3121 atttatcggt tcttagaata acttttaggt aatacaataa taaatttagt aaaattatta
     3181 acttcggatt ctactttaat gaccccttga tgctgctgaa cgataatatc gtgagcgata
     3241 gataaaccga gtccagttcc ttctccaggt ggcttggtgg tgaaaaaggg atgaaagatt
     3301 cgatcttgca tttctcgggg aatcccatct ccattatcct taatagtgat ttcaatcacg
     3361 tcttccaagt cttgggtttt gacggaaagg gtaggggaaa atgtttctcg atcgctcctc
     3421 gatcgtgttt gaaagcgtat tgctttttta tgcactgcgt aaccagcgtt attaattata
     3481 tttatcaaag cacggctgat gttctgcggt actatgttta aacgatcgat attattatca
     3541 taatcagtct caacagtcat gtaaaaagat gaatctttgg cacgcattcc gtgatacgcc
     3601 aagttaattg cttctcctag caaagtgttc gcatgagcca tctgtcgctc gtctccagtt
     3661 tgactgcgag agtgcatcaa cattccacgc acgatattat ccgctctttt gccatgctcg
     3721 ttaatttttt gagcattttg gctgaggtca cttaaaatct cttcaatata ttctttactg
     3781 tctggctcta attggtcttt ttgcctttca atttctgcta gcaattcttg tgttaactct
     3841 atagaaagtt cggcaaagtt attaacaaag tttaaaggat ttttgatttc atgagcaatt
     3901 cctgctgtta gagttcccaa agatgctaat ttctcttgag caataatttg cgcttgtgta
     3961 gcttttaatt tttccagtat gcttgccaat tcctgatttt tttcttgtaa ttcatgagtc
     4021 ctcacttcta ctttttgttc caaggttcga ctgtaatctt ctaactgttc gtacaaacga
     4081 gaattttcaa tcgagatagc tgcttgggca gaaagaattt tgagaatttc gacacgatcg
     4141 cttgtaaagg ctcctgttgt caggttattt tccagataga gaataccatt aagtttgcct
     4201 tgataaagta ggggagtaca aagaatagac ttgggttgag tggcaatcat gtagcgatcg
     4261 cgaataaatt gtcctccgtt tgacgcatca tttaaaatta cgttttcttg agtgcgagca
     4321 acgtagttaa taatcgcaga tgataacaag ggaatctggc tgttagagtc tacagagtct
     4381 acaggaatag atctaagtac agtcacctca tcatcattaa ctaccccctc agcttcaatc
     4441 aaccaattac cctctttatc tagaattaag aacccttttt ccgcacccgc attttcaaga
     4501 acggttttca tcaagttttg tagcaattta ctcagaacga tttcgcccga aatagtttgc
     4561 gatgctttca aaacagtggc taaatctagc acctcactag aagctgaagt actagttgta
     4621 gtagtattta tccgagaggt tttgctgcca agtgatgttg aaacaagcaa ttgagggtat
     4681 ttttcttcta aatcttctac tttacgcttt gcgccccaaa gctgatagcc ttggtaggct
     4741 tttctcatat agagttgggc aaattccgct tttcctcgtt ccaaccaaaa cttagcagct
     4801 aattcattcg acaaagcttc attttgagta aattcgtttt ttcttgcaga ttcaatcgct
     4861 tggtcgtata aatccattgc ttggtgccac tgacccgaga gccgagacat ttccgcagcc
     4921 actaaaatat atttatgtaa gaaattctcc ggacaattat cagcccattg tttcatatat
     4981 tgctggttta tttccagttg atgccagtat ttattccgtt cacctataga agcctgagga
     5041 tacagaaaag ctaggtttaa ggagtagtaa aaattatgct cggctattgc gatagttccg
     5101 ggaatataat caaccaattt tcctgcttgt tctagatatg tcaaatcaat tggtctacca
     5161 tatagataaa ggatttgagt cttcaaaata taataaaagc agatggctgc aagagtttct
     5221 ctttgagcat cttctaaaaa acatttttca ctggtatctt ttatatcaaa acaaaatttg
     5281 tcttgggtaa gccccatcaa attttccata aatattgtgg cacccaatat acaattaatt
     5341 gcccactgat tctgagtttc ttgactaaac tgtaaactgc gcgaagcttc cttctgaagg
     5401 gagtttaaac ttttaccttg acagataaga ttgtataagt tgtatgtcat ggtgtatcca
     5461 accaattgga actcaccaac ttgcaaccct gcttcagctc cttcattatt aactctctca
     5521 gaaaatttga tgtgcttgag ccagtgcata gtgaaactgc catgaacttg tgtaactgcg
     5581 ctcttgcaag accaatccct atacttatca gagagtttca tcccaagaga gctgtattca
     5641 taacccgagt gataatcgtg taaaacatgg gtattaacta ctccaaagaa gctataaccc
     5701 atggaagatt tttccatgtg tccgtattta atattgagat taaccagttt cgctgcaaca
     5761 agatacatca gcattggatc taaaatccaa gcagcaggaa agatgcgagt cagtattttt
     5821 aaagcagatc ttttttccgg gatctccatt tccggattgt taaataatac agagatatca
     5881 cgctcgccta aattttttcg atattctaca agctccgtct caaaagctgc ttgcaaattc
     5941 tgtgttggta ggtcaattcc caaagatttt aaggcaattc gtcctgtctc tattgcctta
     6001 ctgtattccc ctaatagggt acactgaata atgcgaagaa agtaatattc cgtgcgatcg
     6061 agaggtgttt tcgcttgctg aatagctgtg tcaagcaaag attgagattt ctcaaagttc
     6121 ccattgagat actcaacttc tgcaagttcc ttgtacagat ctagtgccat ttcatagcga
     6181 tcgttccaaa tattgcccgg aaattcattt gccgctaaaa gtaagtattc tctagaagca
     6241 gtataagcag ttgcctcttt agcttttttc cctgcatgta aattgaattc tgctagagat
     6301 tccttttcag ccaagttttc tatcaattct cgtcctttat tcagatgatc gaccaaagta
     6361 aaaacttttc cttctcgctc tgcttcactc atgttagcta gcaaaagttt accgatttga
     6421 aggtgaactg ccttcttcag atcgccatca atcagcgcat aagccgcctg ctgcaccctg
     6481 tcgtgcagaa acttataatg ttgaataacg agttccgctt caattggtat gtctgaggtc
     6541 gtttctagct ctgagatagg ctgaattaaa cctaattgga ttgctgacag aagagatttg
     6601 taagtttcgg caggtgattt ttcgtaaata attgagagtg ttgtgaggtc gaaactgttt
     6661 ccaacacaag ctgctaaacg taatgctttc tgggttaatt ttgagagttt cctcagcttg
     6721 ccgagcatta aatctaccac attttctgta atgcctaaag attcaatttg agaaatattc
     6781 caataccagc acttttgctg tcgctcgaaa gtcagaaggc tttcctgata tattgttttg
     6841 aggaactcat taataaagaa gggatttcct gaagtcttgc gatagactag ttctgctagc
     6901 ggttttacta tttctcgatc gctatggagc gtgtcggcaa tcatttgagt gatttcctct
     6961 agctttaagg ggttcagaat aatagtgttc acaattgccc cttgctgttt caatcgctca
     7021 ataactaaca ttgtcggatg attggcactg acttcgttat cacgataagc accaagcaat
     7081 agcaaatatc ccaaacagtt atcggtcatc atcagctcga taagcttgag actcgcagag
     7141 tctgcccatt gtaagtcgtc taggaaaatc actaatggat gcgatcgctg acaaaaaacc
     7201 cggataaaat tctgaaagac tgcattgaag cggttttgag cctcagttgg ttccaatggt
     7261 tgtacgggag gctgtggtcc aactatttgt tctacctcag aaatgacttc aacaatcact
     7321 tgaccgttaa cgccaaaagc agcgaggagt ttttcccgcc acctagccag ttgagcttca
     7381 ctttcagtta ataactgtcg cactagagac ttgaaggctg aaacaactgc ggaataaggg
     7441 atattgcgct gaaactggtc gaacttccca gatataaagt agccgcgttg ctcggtaatc
     7501 ggtttgtaga gttcttggac tagtactgat ttcccaattc cagaataacc cccaactaac
     7561 accatttcac tttgctttct acctgttctt tggaatgcct gttcctcaag tgaattggat
     7621 tcggcaacat gcttgtatct tgagagtaag gttgctattt cagtgtctcg accataaagt
     7681 ttttgggaaa ttttgaatct gtctgaaatg tcgtaacgag caattgggaa ctctgaaatt
     7741 tgcccagttt gctgtaactg tatcagacac tcttctaaat ctgctttaag ccccaacgca
     7801 ctctgatacc tctcctcaga agttttggct agtaacttca tgacaatatt ggaaagagtt
     7861 cggggaattt ttgaatcgac ttcatgggga ggagcagctt gcttggcgat atgacaatga
     7921 atcaactcta gaggatcgtt agtttcaaaa ggcagccttt gagtgagtat cttgtaaaaa
     7981 gttgcaccca gtgagtaaaa atcagtactg taatcgagca cccgattcat tctacccgtt
     8041 tgttcgggcg acagataagc taatgttcct tccaagacgt tcggattttt tattgttgga
     8101 ttttcacggg taaatactgt ggatatcccg aagtctataa tcttcagttg tccggtttct
     8161 aggttaagaa tgatattaga aggattgata tctttgtgaa tgatattagc agcatgaatt
     8221 tggctgagtg tctccgcaat ctgaatggca atgacgagaa agcctggaag tgtaaacttt
     8281 ttggattgca tcacaaggtc taacgatttg cccccaaaat cctctaaaat cattgccagc
     8341 gtgtttttat aaggcagtaa attgtaggct ttaatcaccc catcaatttt tagagaacgg
     8401 gtaatttcgt actcctgctt gtaccgagtg agttctgagg gagtcggata atcttccttg
     8461 agaattttga gaataacggg ttgagtgatg gagttacaaa cagatcgata gactaatgaa
     8521 ttagcacttt cgtaaatttt ggagataatt tggtagtcgg caatagcact catttttatt
     8581 attttttcaa aggatgcact tttgatgctc gactcaagta acgggtctgt cgtattttat
     8641 cttcctaatt tctcaagaag taattaataa tatattatat caaattgtag tctcatacac
     8701 tacatgaagc aagtcatctt cagatgtatt tgccctacct gctaaattcc tgcgaagtgt
     8761 gaagatctct ttctaattaa gtcgtatcat aattaagata aatacccatc cgttttaaga
     8821 aggcatgggt ttctaagagc taattcataa aataaacatt aagactctgt atgttaatca
     8881 atagggtcga gtattagtct aaattgtaga atcgaactgg attatcccaa agaatctttt
     8941 gtacaacttt tttagaaagt tgattttgaa gtgctacgac ttctgcaacc acttttggat
     9001 gatgatccat gtgggggtag tctgacccaa agattaagtt atctgaacca agatattcga
     9061 gaatctgact cagataaggt tctgaaggct ccatagagat aaagcattga cggcgaaagt
     9121 actccgaggg cttcattttt acgttgtctg caacttccca acgaagatct tcgtactcgc
     9181 gatcgagccg ccacaaccag taaggaagcc agccacatcc agactcaaga aatccaactc
     9241 taagcttggg atgacgttct aatacccccc cttcaatcag cgatagcaac gccatcattt
     9301 gttccatcgg atgagagcaa gcatgtagcg caaagcgagt gttgaagcga tctgctcctg
     9361 cgctaggtaa gcgactgtga gtggactcat gaaggctcac agcaatccct aattcctcgc
     9421 actttgtcca aaacggttcg taagcgcagt cgctcagaac tctccgtttg acaggattgg
     9481 ggcgtaaaaa aactgatttc cagccaaact ctgctattct ctgcaattcc agcaccattt
     9541 cttctggtgc gtgtaaattg acaacaccta cacctcgaag aattcgtgga ttgtagctac
     9601 agaaatcacg aagccaatta ttgtaagcac ggacaaatgc accagctagt tgtggtgcga
     9661 tcgtgtccac agcaacgatc catgagaagt aagtcggata aataaacgat atatcaaccc
     9721 ccatctgctg catagctcgc acgtgagact cagcatcaaa gttgttcagc caagataggg
     9781 gatacgcttg agtcacttgt ttggcacctt cttgatggag ccgattcgag tatttgttga
     9841 caatcttttc gcctgcaagc gttagttctg gagacagcgc aaagctctta aacgcgggtt
     9901 cgaggtaatc ttgccacatg tggtgcggct catagacgtg ggaatctgca tcaataattc
     9961 gatatccttc aagcatggcg gggctgacta ataagtaaag ttacatccac atgggtattg
    10021 gattcaggca ctcttctggt gtcggttctt tcaaccaacc caattctact ggaacatcat
    10081 aaagtcgtcc cggagccaag cgcttccaga agtggcgcat tcctggaatt ataactttaa
    10141 caactttcag cccgatatca ggacgggttt ggtcgagaac tagcatttcc atgccacgtt
    10201 gttctataat ttgctgacag agtttaatat catcaagaaa gttatcgttt tctatgtaag
    10261 agtagtcaaa agactttttg acagcagcat ttttatctgg aattaaataa ggctgatttt
    10321 ccagcgtcgc tgttttccac caatcgagaa cgggtggctc agcagaggta gcatattgag
    10381 ttatgccatt ggcatcagca gttaagacag caggaagaat ttggttcatt tccgtcagtg
    10441 ctctttgaac ggcgagtttt ggatcgaagt gagcaccaaa acccaatatg atgtctttaa
    10501 cctggcactt acttttataa ctgattgcgg caaaggctgg aatatttaag tcgctggtta
    10561 tatcaagaac ccaaaattcg cgatcgaggg attggtaata acttcttaag gcttgaaaat
    10621 acggctcctc aaaactctct aaatctactg ccgctctttg agtacgattg taccaccaca
    10681 aagcaacact atctcgctct accaattcca tgaaaccttg tacgatcgct tcttctaaag
    10741 tattgcctgc tgcacaccca ttagtgtctg cccaacagtc tggctgagaa gacatgggat
    10801 agccaaaata acaataagcg gttggcagat acttaaagtc tcggtaagtt aatgaccaaa
    10861 caggtgtcca ttcaatttct ctttcttcat caaacggttc gggaaccctc tgaaaaaaac
    10921 tgccacaatg agcgttccac accgagcgtt catcatattg agcttggctg aagttcatgc
    10981 aagtattggg atggatagcc ttgttgttca tttttcggta actgctctta actctgattt
    11041 cctccccctg aaaaacgcca gagtaccttt caatagcttc gcaaaaacca cttgctcttg
    11101 cttgagcgtc tgttctccct tttcctgcac ttctacctcc aatattcttc tctaaaacac
    11161 ttaagtcatc aaacactgag gcaaaatgat gcttggcaaa ataggtatga gttaaacccc
    11221 tagcatcgaa agagagtttg cccaggtctc gcactactcc tgtaatgggg cttatatggt
    11281 atcgataccg ttccaaggtt gcttctggcg aaacgcaacg atgtccgcca tcagccgtaa
    11341 aggttttttt cctgtttcca agtatcaaag gtaaggggct caaatattgc tgtttgagaa
    11401 tgccacagct atgacactga ggacgtttga tgagaaaatg gctctgtgtt tctagtgtaa
    11461 gagtatcgtg ggtcactaat atcccttcaa ggcgcttgtt ttctgctttt acgatccact
    11521 gaaggatttg agttgctgcc attgttatgg cagtttttag tgttgtgggt aagtcagcca
    11581 gtggtggcgt taaaggtgat gaaacacgat cgcgtctttg gataaatcct tcaactgggc
    11641 ggttaccttg caaacgttgg gacaggcatt cccaacaacc tgttttttca ggatgaaata
    11701 tcggtccaat ccagataaca gttccgattg gtttaatcga catccaagga cgcgatcgcg
    11761 ccaagttttt ttggttaatt tcgaccaatt ccggtcgcaa gtagtcgtcg gttaagacaa
    11821 cttcaaaatc tccttctttg acaacttgaa tttgcagtga ctcgagagta gcaattaatt
    11881 ccgatacgga cagatttccc aatgctttga cagtcactgt agttgcttgt aatctgcggc
    11941 tgacatcttc agttttgact tttaaatgct cgcaaaatac ggctatattt gaaggtaaaa
    12001 cctcttgatg ttccatgaga taacccttct gctccaattc catcagtgcg taatagatgt
    12061 agggcaccgg gagcttatct tggagttgtt gaacaatttc atcaacagtt cgacttccat
    12121 caagcaaggg acataacaat tgatagaggc tatcttgaag cacaattgtg tctctttcag
    12181 atatgaggaa gactccttct gtctcaacta tttcgatacg aaagcaagtc ttaaacttcg
    12241 gttttctaaa cattttgcct gataattttt acctcgttgt aagggtagca tcccgtttta
    12301 gcaaatatac cttcagaata gaattttgga gctacacaaa caaagtccac ctccgtggac
    12361 ttagcttgta tatccacaat ttcaattact caatgtttgt tctaaattgg gatacccccg
    12421 ttgtaagtag ctcaaacaaa ggaaatgtaa catactttta agagcgtagt tgcgttgtct
    12481 ttgtactaag cgcaactaca aataggttat atttttttgt tgagctaccg ggcaaccatt
    12541 aaatttttga aactttagga gccagaaaca ggaatataaa cagatggagg gaggtattca
    12601 ccgctattgt tgtcttgtac ccactgattc aactgttcct ccgtgacggt aaattcgctc
    12661 aatgcaggac gtggtggata ggcaatagta gcaagatatt ttgcttgatt tttgtcatct
    12721 tggcgaattc tcccagtaaa tgaatctact actacctcaa agcgaaagtc ttgtatgaga
    12781 ggatcggtaa aaatgtagtc gtttgcagtc agttttcggt aaacatcaga taaggtcagt
    12841 tgaatatctg gtgcagtttg attggcaatt atgacttctt tgataatttt gcttgtttct
    12901 tctgctaatt gagcggatgg gggatcgcca tactcaattg ctgctagacg agctagggct
    12961 tgttttttaa gaatggaact gaaataattc ttgagttgtt gctcttgcct tttcttatct
    13021 tcatctccat caaatgctaa aaaagtagtc cacgtccaag ctataatttg agtccattgc
    13081 ttaataataa tccgaatctt tgcgatattt tcaggagttt gtaactcttc aggtaatgat
    13141 gtcatgtatg ttgtattaga ctgctctgcc atttttaaaa ctccttaagt tagtttgtcg
    13201 cgctaggagc gctggaatta gctctaccca ttgggaaact aaagtctgta aaaagttgcc
    13261 tattagcttg cagtgttgct ccggtatggc attctatgca actactacgt gggatgtatg
    13321 gttctatagc aacattggct aacggggact ttggcgtaac gtccctgaga cttgtgttgt
    13381 aaggcagact ggggtttgtt agccactgag taccaattaa ttggtagtat tgccagaccg
    13441 atgattgaga gatttctttc agtgcgtctt gccactgctt attctgttcc aatctttgag
    13501 cattgagcgc tgagtttggt ggacgaatta tctgtgacgg aatttgattc tcaattttgt
    13561 ctcctacctt tttgacagca tggggaacct cttgacgcca aaggtatggt ttctctacat
    13621 atggcttgtt ttcttgacag ttttccctac aatccgggtt gtacaacgtg taacgagccc
    13681 ggtttgaagt gctatctgga acattatcta cttgctcaaa agtagaccaa atccacccct
    13741 gctcgcttgt tttatgctta atatgaaagc ctattaaacc tacctcaact atctgactaa
    13801 attcttcatc ggtatcgcta caaagtgctt taccttccgt acattcagtt gactgtgctg
    13861 gaatcgtcct ctgtcgctta gttgtgtagt aacgagcttt ctcctcctga gatgtctgtg
    13921 gatcgaaaac tcgccaagct gctttaatct caatcgcccc ttctttctcg tatgtgctgc
    13981 aaggaacatt gagggggttg gcgtttgcat cttcgctaca tacaagcgca aatttcttgt
    14041 cgtcgttatt gaattgttgt aagttgaccg cgtcatacca cttgttttca acaatttggt
    14101 tgaattcttg tgggttaatg tatgcctcca taataatgta gttgccttgc tggtcaacaa
    14161 ggggtttgtt tgcatttgta ccgttgctat ctagtttctc tgactctgtc agttgtaatc
    14221 tagagttttc tgtctgtaaa cctcttgtag aggtgacatt caaacaagta aaaggtttag
    14281 ttggttgtat ggatggttct tttcctgctg aaaggaatat tgtctctgga gtacgataga
    14341 actcccagag acggggagca tttggaacct caccaatttt ctcattccgt aagggttctc
    14401 cttgctgaca atcagcaggc caatttaaag ccagaaaaac ctgccaagca aaattgtcga
    14461 taaaagcgac tcttggcgta ttagggtata gcgcctgttg tttggctaaa ttgggattgt
    14521 gtggaatttc agaagtgatt tctggtttaa gttgaaatcg gctttggctt tgaagttctt
    14581 tgtcaatttg agtgtctgct agacctgtag aaacacaacc taagaccaca actgaaatag
    14641 aaataattga aatgaaaatg agacgttgaa tatttctcat atcgattgtg ttgcaactga
    14701 ttgtaattta tgccacgcta tagcttgtct ctagaagaga ctgagttttt ctgcaactac
    14761 tttgaaggac atctttacaa aggaagctcg tgtattaata gctatttttc tgtagaaatg
    14821 ggttaatttt ttgcaaattt tgactgacat tttagtcgaa ctaaaatcgc agacttgatg
    14881 attcaagtat ttgatttctc ttatttttac ccatgattta acacccaatt acagaatatc
    14941 cttaaattgc atattaaaga acatagtatt ctgtaaaatt tacatttttt tatattttta
    15001 ttaaatatga gttttatatg agtttaatat tgcaaaattt atatataata gttattttgt
    15061 ttatttacaa tacttgtttt tatgagataa actttgtctg caattctaat aagaaattta
    15121 atctaaaaaa cataaaatat ttgtatttga tactgaatcc gcctcttgta cccccttgat
    15181 aattaagtcg ttgccttgcg gtgagtccag caaagcgtgg cagtaaatgt tgggtttcgt
    15241 tcctcaaacg ccacatcgct caacgggggg ctttggggtc cccacgaagt ggggttgggg
    15301 ggaaaccctc tccagttgct cctcttgggc aaagacgaca ggtgctatct cctgcggaga
    15361 cgctgcgcga acaacagagg aaacctcccg aagtttgcgg cttggggagt cagtgcggtc
    15421 ttgggctttg cccaagtgaa gcatctgagg tggaaacccc caagccgcaa cttctctggg
    15481 caacgcactg tctccccaag accgcacggc gctgctctgg gcacgcgagt ggctccccaa
    15541 cctacgtgtt ttcgcatttt tatgctttaa agatgcttga aagaaaaatt ggtgggagcc
    15601 tcgcaggcaa taagttcagt tacaacttag attgaaaata cttacgatat aattgacaac
    15661 tcggagttgc tttattgtta tctagcttaa taaaacccat actgctaagt ttataagcaa
    15721 taacaggttc taactgcaca gcttctgtag tatttatcac tttatgaaga gcagatgcta
    15781 attccggctg tgcttccaaa gtgacccaat gccgctgtaa atgatggtag tatatgcctg
    15841 taggagtggc agaattttgt agcagttgtg tcaaagttat ctcttgctga ctgaggtgat
    15901 agagcgctaa atgtaccagt gctggatgtc ctccaaccat atccatcaaa agggttgctt
    15961 ctaaaccatt tttccaagcc aatccataac gtaaagctaa ctgctgtact tgttcaaaac
    16021 taaagctttg taactgaatt ggaagcccga cattgaatgg tgactgatga agttgcaagg
    16081 gaacgtagac ttctgtggaa tgaaccacaa tcaaacgcag cttttgccaa attggtcgtc
    16141 tttttgcttc ttcataccac gatcgcaata acggtaaaaa ttctttcgcc acctgtggat
    16201 actcaaaaat ttggttcact tcatctaaag ccaaaaccac aggagaatca atatattcga
    16261 gtacgtagtt ttgcaagtat agcgaacaac tgactttact cccaatatct tcatcccaat
    16321 attcatccat tcttggttct atctgaagct gacgcgaaat attagcacac agccaacgca
    16381 agaatcgatt taaatcgctc agaatgtcgc gatcgatttg ctcttcaaag ttcaacccga
    16441 tggtacggta gccaatgcag ctagcatatt ccaaaattct tgacaacaga gaagtttttc
    16501 caatttccat tggaccttta atccgaatta aagctcccgg cttagtaatt tctctgtaaa
    16561 tttgtgcgct aacggcagtg ttttcaatat agtaaggaga gtctagggga acagaaccac
    16621 taggatacgg aggtaatagg tcttgatgaa tgttaataga tggggagagc attggggttg
    16681 taaagggcga tcgcgtttct gtttgcattc ccctaagatt gaaactcgga gttgagtttg
    16741 gcgaacttat cacgtcttcc cactcaatcc gaacaccatc ttgcaaccaa accatagatg
    16801 attcggctgg gttttggaaa ataactggta gccaagttgc acaaggatat tctttctcca
    16861 atgcttgcaa tctttcccgt gcagaacgta gcgccgcata taaggatttg ccagaagaaa
    16921 attcagttat gaaatatctt aaaaattctt gagccaccac atccggaaca gcctcccgca
    16981 ttacgatcga ttgaggtatg ttcacatctt cgagttgttg cgccaatccc aaaccatcac
    17041 aggagttaaa aattgcgagt tttaacccac gacccattgc ttccttgagt gcatacttaa
    17101 gtttctcaag ggaaattgta tctgtgggat tgatttgcag aatccctttt tcttcactgg
    17161 aactatgacc tgcaaaaaaa agaatatccc aaccttcttg ccaaagatgg tcattcaaat
    17221 cgcgtaaatt tggctcaact aaaaatttaa tttctgctcg atgggataat ttttccaaaa
    17281 acattctatc gtgactgata tcaatccctt gtgcatttcc aaaaattgcc agaattttca
    17341 gttgatactt tcgatgatta ataggtaatt tattagtatt ttgatactct gttgcactta
    17401 aagcgacttc cccataggga taatcttcaa aaaactccca caaatgccag ggtagacgtc
    17461 tcaataaagg atcgttagtc tctataatga agcgaatttc atcagatggt tttaattgtg
    17521 tacgtaattg cctatcgatt ttacgaaatt ctttagagtc caaccatgta tttaatcttt
    17581 ttgacagctt ttgagataac ttcagaatat cagcctcaga aacatgagtg agccctactt
    17641 ctgagatttc aagataatca tctgtttcga cactatttcg ccaacaactc aggcgttgat
    17701 agaaggcata ataaagagct tgccaatttt gatagagttc taaaattttt ggtgcggctg
    17761 gtaaactagc acttattttc atgtggtagg ggttgctagc ttcaccaact tgtgcggtga
    17821 cggtagcaca gccatcacgc aagtttccct gacccaagct taaaacaact aacctactca
    17881 taagtgttcg atctcgtaat agtcaattct tgacttatga gattgactcc cacatttgca
    17941 agaagtaatt tttattaaca attgttttaa cggtgatagc ggtttcttta acgatagaac
    18001 gatttatgaa ataaatattc ctgttccatt cttggcactt cactttattt caaaaaatat
    18061 agaatcattc tcgctttcag aattaaaagt ataaatcgat ctagtaaagc ttattttttt
    18121 ttcatccaat tttttttaac gactccctaa tgaccacaaa aatttttaat gcggactttt
    18181 tcattgttgt atttactgaa aattatacta gctttttcaa aataggagag gaaaactttc
    18241 gttgaaaata ctgccgatac aactcgcaac tgggaactgc gcgatcgttt tccaacttaa
    18301 ttaatcccat actatttagc ttgtaagcaa ttacaggttc tagcaatacg gggatagtcg
    18361 tttgcataac cctttcaaaa gcagatgcga gttctggctg tgcttgtaaa gtagaccaat
    18421 gacgctgcaa gtgatggtag taaatcccac ctggcgtaga agcatcttca agaagttgcg
    18481 ttagagtgat ttcaccatca cttaggtgat aaactgccag atggacgagt gctggatgtc
    18541 ccccaactac atctgttaga aatgttacct cattatcatc tacccaatca atcccatagt
    18601 attgggataa ctcctgtact tgagatagat taaagtgcct taactgaatt ggcaatccca
    18661 cattaaaagg cgattgatga agctgtaaag gcacatagac ttctgtggaa tgtacgacaa
    18721 tcaaacgcaa cttttgccaa atgggctgtc ttttagcttc ttcgtaccac gatcgcaaca
    18781 aagggaaaaa ctctttggcc acttggggac tttcaaaaat ccgatcgaca tcatctaggg
    18841 ctagaactat tggagagtca atctgctcga gcacgtaatt ccgcaagaaa agagagcaac
    18901 tgaccttact accgagatcc caatcccagt aatcgtctag ttttggctca agtcccaatt
    18961 gcaaagaaat gttagcacac aggcaccgca aaaatcgctt gaggtcggtt atgatctctc
    19021 cttcaagatg ctcctctaaa ttcaggctaa cggtacgata accaagattt ttcgcgtatt
    19081 ctataattct taacagtaca gaggttttac ccatctcttt cggtgctttc agccgaatca
    19141 atgctcctgg tttgctgatt tccgcaaaag cttgctcctg gatagcagtg ttctgaatat
    19201 aatagattga atctagagga accgaaccac tcggaaagcg gggggatttt tgtttatttg
    19261 tcaaaaagtg agtggaaagc tgtcttgacg gtgtagcgat cgctggcaaa gcctgtgctg
    19321 cataaaattc taacagcgcc cgacagtttt ttttggtcac gcgcctgcca ataattaaag
    19381 atagtttttg gcataacccc ggagcaacaa cattagttaa gtaaccggga ctgtatcccc
    19441 ctgcttgagc catttgaccg taagtttgac tctgccaaat accgcgcagt attaatgtct
    19501 ctgtatcatt cagagggcga ttttgggttt ccaatagctt gtgattgaca attgcaagta
    19561 gagaatcaag agtcatgaga aattgggtac tattttcctg ccgatgaatt aaattcacgg
    19621 cttcgctttc aacaatctta gcgataatga ttatagaaac ttttgtctaa accccttcct
    19681 actgcccgag ataattaatc tcgaccacaa ccacggaacg cacattatta taaagttata
    19741 gtaccgtttt ctatgcctaa gttgagcaag ggtataatta atttttttta tagtcatttg
    19801 cccgtcggga ctggggaact cagagccccg acgaagtggg gattaaggta tggggacaag
    19861 gaagaccggg gagaatcacc gaacgcccgc ttctcttttg ccaattaact actcgttaac
    19921 tcaatccagt atcgttcgta caatgcttca acttcttgac ccaaaggagc taaacgttcg
    19981 cactttgtta aaattgcctc tgaaggaaac aaattgggat tattttggat tttctttggc
    20041 aattgctcaa atccagcacg gttgggagtg gaaagaacta atatttggct catttcagat
    20101 gccacttccg gtcgtaaaat taagttaatc caagcataac ctgcttcaat attgggggct
    20161 gtcttgggaa tgacgacggt atcagtccac aaagaagaac cacttttggg aatgacgtat
    20221 ttcagtttag gattttctct aacaattttc acagcatcgg atgaataaca cattgctaag
    20281 agcaaatctc ctgcaatgat ttgattgcgc catgcatcag ttgtaaaagc tgctacatcc
    20341 ggtatgagaa cctttaacgt gtcaacagct tgtttaattt cattttcatt ggttgagttg
    20401 taagaataac cgagcatctt taaaactgca cctatgactt ctcggaaatc gttcattaac
    20461 gccatccgct ttgacagaac ttgtttgttt tcccaaagat agtcccagtt ttcaggtgga
    20521 gttgttagct tttcggaatt gtaaataaaa cctgtggttc cccaactaaa aggaatacta
    20581 tgacggttat tgggatcgta gataggattt tgaaacctgg gaaataaatt gtctaagccg
    20641 attatgcgat cgcgctccaa tctaatcagc aatcccaagt ccaccatttt ccgtaccata
    20701 taatcgctcg ggtaaatcac gctataagca ctaccacctc ccgcttggat tttactgagc
    20761 atggcttcat tggaatcaaa caaatctgcc aatactttga tccccgtttg agcgctaaaa
    20821 gtttttagta aatccttatt cgtgtattgt tcccacgtgt agatgtacat ttggtcgcgg
    20881 gaaccagtgg tagcggatgc acggacgttt ccaagtcgcc aaccgcaccc tgctagagac
    20941 aagctagaga gcgctgctat tcctgtaata aattctcttc tgttagtcat gactcactaa
    21001 agccaaacaa tcaccttctg tccaccaagc atagatagga gtttcacgat ctggcaaatt
    21061 aacaaatgtg ttgggttgta aaacattaat ctgtaacccg tttattaatt gcacaacata
    21121 attgatgtgc gttcccaaat acataatatt aaccaaccgt ccttcaaagc agttattttc
    21181 tacgctgggt ttgtaaagag atagctgtat tttttccggg cgcacgctaa caacgataga
    21241 ttgtgatatt tctgttggtg tattttcttc acgagtcaca ataatggaaa gccctgtttt
    21301 tgttaaaatt ttaacgtgag aagcatcagc gccagttatt tcacctggta ataaattggt
    21361 atcgccaata aaattagcaa cgaatactgt ttgaggttgt tcgtaaattt cgctgggagt
    21421 cccgacttgt tcgagtttac cttgattcat gacagcaacc cgatccgata aagatagcgc
    21481 ctcttcttga tcgtgagtca ccatgatgaa agtcaatccc aattctttat gtaaattgga
    21541 cagttcaacc ctcatttctt ttctcaattt taaatcaagc gccccaaggg gttcatctaa
    21601 aagcaagact gcagggcgat tgacgatcgc tcttgccaag gctatccttt gctgttgtcc
    21661 ccctgagagt tgattgggaa aacgcgatcg taaaccctcg agctttacca attctagagc
    21721 ttgtttgact ctgctttcta tttccttttt acggagattt ttaagacgca gtccaaaagc
    21781 cacgttctcc cagatattta aatggttaaa cagagcataa ctttgaaaca cagtgttaac
    21841 agggcggcga tatgggggaa cactagtcat agactgaccg cgaatcaaca cttgacctgc
    21901 atctgctctt tcaaaccctg caataagcct gagtgtagtt gtttttccac aacccgaagg
    21961 accaaggata ctaaaaaatt ctccttgtct gatatccaag tctactccgt ggacagcagg
    22021 ttcttggtta aaaaacttaa aaacgctaag taattccacg tctagtggtt caaaacctgc
    22081 tgttccccct tgattctgaa ttagagtctg agccatagta cttgatttca tcctgagagt
    22141 ataagtgttt ttgttaatca atgtagtcga tgaggcaaat gagaagttac actttggttt
    22201 attctatcgg tcaaagataa cttacagaaa aatatactgt taagtttaat ttg
//
