LOCUS       NZ_JHEG04000001        20861 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2160115
            Orig. end                         :: 2180976
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20861
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="8"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20861
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20861
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10861](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10861)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    321..341
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.4"
                     /tool="antismash"
     misc_feature    complement(322..342)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.98"
                     /tool="antismash"
     gene            1684..2205
                     /locus_tag="HC643_RS08710"
                     /old_locus_tag="DA73_0400008705"
     CDS             1684..2205
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017745439.1"
                     /locus_tag="HC643_RS08710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008705"
                     /product="histidine kinase"
                     /protein_id="WP_038091453.1"
                     /transl_table=11
                     /translation="MKFTKLATSALVFASVIFSAGIASAQSVPTRGTSANYLGAGVAAG
                     VTNGGQDNDAATLGGNIQGRFAVPKAPVSVRGSVLFGGDATAAMPIVTYDVPVAKDTNV
                     YVGGGYSFVTDEGKSTPLGNKNSPVVTIGAEREIAKNFVLYGDAKWGIDAYENSSADAL
                     SIQSGVGLRF"
     gene            2461..4194
                     /locus_tag="HC643_RS08715"
                     /old_locus_tag="DA73_0400008710"
     CDS             2461..4194
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408530.1"
                     /locus_tag="HC643_RS08715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008710"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_038091580.1"
                     /sec_met_domain="GATase_7 (E-value: 2.1e-15, bitscore:
                     55.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 7.4e-68, bitscore:
                     228.6, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="QueC (E-value: 1.1e-05, bitscore: 23.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKSRKSKIPFFNPDPSWRVAWGAVDANYEDIAWRDDQVTVIVPR
                     TASGVITEKLAIARGEQFVVVGDVWLTNQVQLLENLGVEPNSFALSPLQLVANLWERWG
                     MKCLNQLEGMFALVIWDREKQVLWSIRDRVGARTLYYTTTGSVRWIAPKLRTLALHRSS
                     DLDLVALRDYLCCAFVPGERTLWQQVRELRPGTVLQLPECKVQAYWQLQEKITAIDKSL
                     AWHSDRLRQLLDQVVREYLPAENEPVGVFLSGGLDSSSITAIAAKFHHSPVHTFSIHFG
                     SECPNELEFSSLVAKYCQTQHHILEITFRDMWERLPETMAYLDDPIGDPLTVPNLLLGR
                     LARESVQVLLNGEGGDPCFGGPKNQPMLINSLYGSVTNQDSLQAYLISFQKCAADLPQL
                     LKPEIWTAVQKTPWVFEEDLYSQASYLNRLMAMNIKFKGADQILTKVSNLTQAALLQAR
                     SPLFDQRVVELSMEIPPEYKLSGVEEKAVLKGAIAELLPPAIVHRPKSGMMVPVQLGFR
                     KYWQREAKNLLLSRNAAIAPYLNQLPIRNWLNYQGDTWSRYGVKLWLLVSLEIWLQVNQ
                     K"
     gene            complement(4255..4452)
                     /locus_tag="HC643_RS08720"
                     /old_locus_tag="DA73_0400008715"
     CDS             complement(4255..4452)
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012628063.1"
                     /locus_tag="HC643_RS08720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008715"
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_038091454.1"
                     /transl_table=11
                     /translation="MGASFTAQLKKILSEGSCYFERQGKGDHEIWYSPITDRRFVVDAS
                     IKSRHTANAILKQAGLPKAF"
     gene            complement(4453..4698)
                     /locus_tag="HC643_RS08725"
                     /old_locus_tag="DA73_0400008720"
     CDS             complement(4453..4698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017316887.1"
                     /locus_tag="HC643_RS08725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008720"
                     /product="DUF1902 domain-containing protein"
                     /protein_id="WP_038091457.1"
                     /transl_table=11
                     /translation="MTQTTFKVQAFWDAEAKVWVATSEDIPGLVTEASTIEALTQKLRE
                     MIPELILLNNIVSSGFAGSISFELISHRQELIEVAS"
     gene            complement(4787..6049)
                     /locus_tag="HC643_RS08730"
                     /old_locus_tag="DA73_0400008725"
     CDS             complement(4787..6049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408524.1"
                     /locus_tag="HC643_RS08730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008725"
                     /product="hypothetical protein"
                     /protein_id="WP_038091460.1"
                     /transl_table=11
                     /translation="MKCVQCGTDNKLKDRTANYGRCKNCSHPFTFEPTSMTGVRFTDPF
                     FAKAIADISANDTLFFTQKQFFYSLNKKLQNKNQGSWVFLWIVFVIASFYFFEYLGLSA
                     LLLVIFFAQIQAIKNSYSQRKKLAKTLIILGAITLIAGIFFSLGVNSFRTFVGSVFLGM
                     LAIYLGTGEIGRSTTISQKLLINNNQLEEWLTSWRRVNNSIDKILPAPQQQNTPVTINP
                     DVTAYSFDRLVVCDSAEIAQMLIANNFHFENNCAILSITGYPQNIFDTTMQMLRRNSDL
                     KVYALHDCSPTGIALLNQIRTRPEWFGESDVIIIDVGLLPRQIIAANRRMFVQTSPESA
                     EAAKQLLPEIRATLSTDELDWLEAGNFVELESFSPQKLIQILNQSIANSRTLNSDDSSL
                     ILTSEGGSINDNSIYINQSFG"
     gene            complement(6080..7330)
                     /locus_tag="HC643_RS08735"
                     /old_locus_tag="DA73_0400008730"
     CDS             complement(6080..7330)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015206565.1"
                     /locus_tag="HC643_RS08735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008730"
                     /product="decarboxylase"
                     /protein_id="WP_038091463.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.1e-22, bitscore:
                     79.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.1e-16,
                     bitscore: 58.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASVKSAHLPFPLELAQELLNTYGSPLYVYQADILEQTIRHITQA
                     FSYPRTQFRFASVTNGNISLLQIFRAKSWGLHANTPGDIYLGLQAGFAPEQIVYSGSNL
                     NSEEMKQVLNWGVTTLNLDSVAQLQLCCEVYHSLTPSLPHFLTPSLRLGLRLNLPEITG
                     DSRIGVRPEEFPHAIALTRQVGLKLSGLHFYRGTGTNATEAFTNVIDKVITTAELLPDW
                     EYLDFGGGFGYSYHHSSAAFNWETFGTDLSNRISHLGKDIELVIEPGRAAIAGCATLLA
                     KVVSVKWHSEKQIVGVDTTVANLSVPTVHGGYREIVAWKNRDNPAHLASSKIYLTDICG
                     NTTYSRDYLGKNCSLPALEIGDIIGVLDVGAYGYAMSSHFLHRPKPAEVLLEKDTHRLI
                     RKREDYSVLLNNQLFHK"
     gene            complement(7318..9153)
                     /locus_tag="HC643_RS08740"
                     /old_locus_tag="DA73_0400008735"
     CDS             complement(7318..9153)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015206564.1"
                     /locus_tag="HC643_RS08740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008735"
                     /product="asparagine synthetase B family protein"
                     /protein_id="WP_050046258.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-52, bitscore:
                     178.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNVEQGDRIIQPKHFIGYWGYGERRELETSLGAVKKTGHNSYQL
                     SSLDSPSESHYPIWNVACIGFSKDFIPSIYFQRHGIERIAALSASGILTDLQDNSFLPD
                     IWVHLQGKNRLILGREPFGRVPLYWAQQGQVIWFASRLQLLLAVVDEPEVSIPALYGYS
                     CFSYIPNPLTPITQVFAVPAGTELVWQSQPDDRKLSTPISQRLLEWCEASVQLQDETTA
                     VKQLQTLLKQGIERQISDLKDEPVGVFLSGGLDSSVVAALLVQAGVNAIAYTLDFGGAG
                     VPEYPYAEIVAQHLQIPLVKVDASPRQIQKAILPTVRALDLPFGDGVTVPLFLLAQRAS
                     QETQVIFNGEGGDQLFAGWTNKPLIAASVYQTENPSGQETFIQQYLRTFHRLWGYEAQI
                     YQPHVYKQIQNLHPEDWIAEALDPTYCKTILHRLRRASLMLKGAQNIHPRATALGFAHK
                     LFVRSPFCDLPLAEWTFQVSGELCLQGACEKYILKRAVENWLPPEIVWRQKRGMGVPLT
                     SWCLNEFWYELGKWLNPGKLRAENCFSPYIASQIAAGQLGATIQGRLIGESLWLLIVWE
                     LWREQVFGEESSKQSFDHPFWLPKQLWRLQKKWQA"
     gene            complement(9155..9778)
                     /locus_tag="HC643_RS08745"
                     /old_locus_tag="DA73_0400008740"
     CDS             complement(9155..9778)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408527.1"
                     /locus_tag="HC643_RS08745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008740"
                     /product="hypothetical protein"
                     /protein_id="WP_038091593.1"
                     /transl_table=11
                     /translation="MSQKLTTEQLTQIVAEVERLQTRREAEIEPEQVKEILQELGLAPD
                     LLDEALVQVRRRQALEVQQKRQRTIAIGAIAAVIVVIAGTLFAMQQQNSVLARVFAQTD
                     RITLTQDNGGDLTDIARQNNPEIFYRVTLKDAPLNQKLDLSCNWIDPNGQVVKQNRYQT
                     REIDKSIWNTQCRYNLSSASTPGQWKVQMFLQNRQLSEAEFQVK"
     gene            complement(10001..10861)
                     /locus_tag="HC643_RS08750"
                     /old_locus_tag="DA73_0400008745"
     CDS             complement(10001..10861)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: NHLP_CD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Goadsporin_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03882.1"
                     /locus_tag="HC643_RS08750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008745"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_162002265.1"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 8.3e-19, bitscore:
                     66.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 1.4e-24,
                     bitscore: 84.8, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 1.3e-15,
                     bitscore: 56.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFYKPMFKPHYHVRVIEPDIVYLLSEQGQCALGGRLYVLLAPFLN
                     GRYTVQEIFQQLNEEVSLFEIQNALVRLNSEGYLSEASVNLPPQVAAFWNGLGAESENA
                     FRKLQDSRVSIISFGRVGVEAFVRALESLSIPVGEGGEFTVVLTDNYLQLGLDEFNREA
                     EETRKPWLLAKPVGTEIWLGPLFVPGRTGCWECLAQDLRNKRETETIHREGMSPSLLSS
                     FAVLPVSFQLGLNLIAMETAKWIIWGEHQQLTGKLISFNLASLSMQHQILNKLLECPVC
                     GGSQY"
     aSDomain        complement(10577..10843)
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS08750_Goadsporin_CD_RRE.1"
                     /evalue="4.60E-18"
                     /identifier="RREFam013.1"
                     /label="HC643_RS08750"
                     /locus_tag="HC643_RS08750"
                     /protein_end="95"
                     /protein_start="6"
                     /score="56.1"
                     /tool="antismash"
                     /translation="FKPHYHVRVIEPDIVYLLSEQGQCALGGRLYVLLAPFLNGRYTVQ
                     EIFQQLNEEVSLFEIQNALVRLNSEGYLSEASVNLPPQVAAFWN"
     aSDomain        complement(10577..10852)
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS08750_NHLP_CD_RRE.1"
                     /evalue="3.00E-21"
                     /identifier="RREFam015.1"
                     /label="HC643_RS08750"
                     /locus_tag="HC643_RS08750"
                     /protein_end="95"
                     /protein_start="3"
                     /score="66.2"
                     /tool="antismash"
                     /translation="KPMFKPHYHVRVIEPDIVYLLSEQGQCALGGRLYVLLAPFLNGRY
                     TVQEIFQQLNEEVSLFEIQNALVRLNSEGYLSEASVNLPPQVAAFWN"
     aSDomain        complement(10625..10843)
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS08750_Cyanobactin_D_RRE.1"
                     /evalue="5.00E-27"
                     /identifier="RREFam007.1"
                     /label="HC643_RS08750"
                     /locus_tag="HC643_RS08750"
                     /protein_end="79"
                     /protein_start="6"
                     /score="84.8"
                     /tool="antismash"
                     /translation="FKPHYHVRVIEPDIVYLLSEQGQCALGGRLYVLLAPFLNGRYTVQ
                     EIFQQLNEEVSLFEIQNALVRLNSEGYL"
     gene            complement(11002..11487)
                     /locus_tag="HC643_RS08755"
                     /old_locus_tag="DA73_0400008750"
     CDS             complement(11002..11487)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015132155.1"
                     /locus_tag="HC643_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008750"
                     /product="GNAT family protein"
                     /protein_id="WP_038091465.1"
                     /transl_table=11
                     /translation="MQLRQANIDDIDFILSQERRDEYATFITLWSRDEHNKNITNPDKR
                     YFIIENESGQPSGYVILSGLQSLNRSIELTRIVVTKPGSGYGKRVLPILIKMIFDEYKA
                     HRLWLDVFEHNQRARYVYQTCGFKEEGVLREAVKQGDNYSSLVIMSILESEYYTANT"
     gene            complement(11837..14248)
                     /locus_tag="HC643_RS08760"
                     /old_locus_tag="DA73_0400008755"
     CDS             complement(11837..14248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015154901.1"
                     /locus_tag="HC643_RS08760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008755"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_038091467.1"
                     /transl_table=11
                     /translation="MDAEAVLSWLETVIPAQTGERLSELQKVILQQVWQGRKYLEIANS
                     YGCTEGHAKDVGSHLWKLLSKALRQKITKSNCRATLERYWKKTSVISNLLDTSRFAENF
                     TIGKEQPRAEFITKQENVNFLGRTEAISHLNTLVNRGVKVIVIQGEGGVGKTTLAQEYL
                     QTQGFDLVLELLMAKETQNITAAEHVIEEWLKQDFDEEPGIEFGVTLGRLKRKLHTCRV
                     GVLIDNLEPALDRQGRFIAKHRNYVEFLRVLADARVQSVTLITSRDRLCEPEVNVEHYR
                     LPGLDLTAWQQFFTKRELPIDFATLQSMHRAYGGNAKAMGILCGSIRQDFDGDTIAYWR
                     EHQAEPLAVVDLKNLVVSQINRLQALDPLAYRLLSRLGCYRYQDVPRIPKEGVFSLLWD
                     VLPCQHQQILTSLKNRSLVECSKDEYWLHPAIRSEVISHLRISDEWEITNRKAAEFWTE
                     SIQKITTFKDALQALEAYYHYVEIHEFEWAGTVILKSRNNQWQQFLPLGSTLYRMGWLQ
                     PLIAAITIIIKNVPSDKNLSELYNILGDLYWIIGKVHAAIECQEKSINIAYRAINSLSR
                     IRENKHKFYYYKMLEVDALLSIGLYKIDLWELDASAQLFQQVIDLAQDTDHHRWAEKAT
                     VCLALVNSYLGILEEARVLADKAYQAIATQQLVKPSGRFAYFMQILGQTYVNLKDFAKA
                     EEMFRMALTFAEESHYTQVQAKTLCGIAEIYRQQAKFELAIDNHLEAIELLNRIGAKCD
                     LAIADFQLGLTFSKIGKKQESRIHFDRAIRLFTEMQAPKQIEKIFKYLQI"
     misc_feature    complement(14297..14312)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            complement(14374..>14526)
                     /locus_tag="HC643_RS08765"
                     /old_locus_tag="DA73_0400008760"
                     /pseudo=""
     CDS             complement(14374..>14526)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002748301.1"
                     /locus_tag="HC643_RS08765"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008760"
                     /product="element excision factor XisI family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RDNNQTHACTMHLEIKDSKIWIQHDGTEVGIATLLLEQGVPKEDI
                     VLGFH"
     gene            14502..14675
                     /locus_tag="HC643_RS08770"
                     /old_locus_tag="DA73_0400008765"
     CDS             14502..14675
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS08770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400008765"
                     /product="hypothetical protein"
                     /protein_id="WP_153021515.1"
                     /transl_table=11
                     /translation="MHAFDYYRVNLRVIKCSDRERYLKQLVSRILQEQIGSSELAQEQC
                     EIRRHLTPQQSS"
     gene            complement(14641..14718)
                     /locus_tag="HC643_RS08775"
                     /old_locus_tag="DA73_0400008770"
     CDS             complement(14641..14718)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020393.4"
                     /locus_tag="HC643_RS08775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008770"
                     /product="element excision factor XisH family protein"
                     /protein_id="WP_137986501.1"
                     /transl_table=11
                     /translation="MLAAERAGEKIAVEIKSFVGGSNVS"
     gene            complement(14722..15606)
                     /locus_tag="HC643_RS08780"
                     /old_locus_tag="DA73_0400008775"
     CDS             complement(14722..15606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015215621.1"
                     /locus_tag="HC643_RS08780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008775"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_202048706.1"
                     /transl_table=11
                     /translation="MLPANPPLPPKLTLPTMYDLPSEDAEEPGLPDEFHDLQPQLLSRT
                     IRLTNYSYERIFTGSDLNLYYDVRHTQWYKRPDWFLVLDVPRLYEEKDLRSSYVVWQEG
                     VNPFVVVELLSPGTQKEDLGDYAELEPMFGERSTEDVSTMSLASESSNGQTLKQVPPRK
                     WDVYERILRVPYYAVFSRYSNRLRGFKLEGGHYQEQTIDAENPRFWISELNLGLGVWQG
                     EFEGIIRQWLRWYDSEGNWILTDTEQAVKEAERERQMKEQEQQKRLKLAEKLKALTPEQ
                     LGALGINLEELES"
     gene            15771..16721
                     /locus_tag="HC643_RS08785"
                     /old_locus_tag="DA73_0400008780"
     CDS             15771..16721
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408620.1"
                     /locus_tag="HC643_RS08785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008780"
                     /product="hypothetical protein"
                     /protein_id="WP_038091470.1"
                     /transl_table=11
                     /translation="MINTLSPMSQVGLASSPTHYFQLLHRIRSLADNYLSIEKLCDRLQ
                     DLPIQFENPQPRPWKQIDWQAISSNQIIGLDREVFLSILRGAMDTEAPIRAYTQTSRQY
                     LENLHPQLARFVGGTVDETGKLIEPGLWEKEERQHTPALMKVYYQLTGEKITATFRTVR
                     DYLPTDDPHEDLYRHGLHRVATEYGATCLYLWLMAHTTGALQDVLEELVQDEINHMSKF
                     WGFGVWAFPDTSLIKVGHTLLKTRHKDYKRNSLMRTLKRMMGTLNWSSWSLTNRITLLF
                     AFSYAMRRLWIWNDRLTPKYLQGLFDHTTLLTPNP"
     gene            16731..17480
                     /locus_tag="HC643_RS08790"
                     /old_locus_tag="DA73_0400008785"
     CDS             16731..17480
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016877742.1"
                     /locus_tag="HC643_RS08790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008785"
                     /product="isoprenyl transferase"
                     /protein_id="WP_038091482.1"
                     /transl_table=11
                     /translation="MTSTLPLDLDPHRLPQHVAVIMDGNGRWANQRGLPRIAGHRQGAK
                     TLKELLRCCKDWGIKALTAYAFSTENWRRPLEEVDFLMLLFEKLLRQELAQMHREGVRI
                     SFIGDLSILPTSLQAEIERSMAETLHNQALHFTVAVNYGSRSEIARACRRIAQLVQQGE
                     VNLEDVEENLIEQTLYTAGTPEPDLLIRTSGEMRLSNFLLWQMAYTELYFTDIFWPDFD
                     RSAFHQALLSYQRRDRRFGQVKTSLSA"
     misc_feature    17964..17981
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.84"
                     /tool="antismash"
     gene            18019..19368
                     /locus_tag="HC643_RS08795"
                     /old_locus_tag="DA73_0400008790"
     CDS             18019..19368
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010995300.1"
                     /locus_tag="HC643_RS08795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008790"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_038091493.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.1e-60, bitscore:
                     202.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNTVDSQPPHHVVIVGGGFGGLYAAKALGRADVKVTLIDKRNFH
                     LFQPLLYQVATGTVSPADISSPLRSILSKSKNTKVLLGEVTDIDPQAQEVTLGEEAIHY
                     DSLILATGAKHSYFGKDQWEEFAPGLKTVEDAIEMRRRIFMAFEAAEKETDPEKRRAWL
                     TFVIVGGGPTGVELAGAIAELAYHTMKEDFRNIDTSEAQVLLLEGMDRVLPPFASELSK
                     EAEASLTRLGVSVQTKTLVTNIEGDLITLKQGDEFQQIAAKTVLWAAGVKASPLGKLLA
                     ERTGSECDRAGRVIVEPDLSLKGFSNIFVVGDLAHFAHQNGKPLPGVAPVAMQEGQYVA
                     QLIQQRMKGKTLPQFSYTDMGSLAVIGQNAAVVDLGFAKFTGFIAWLFWLVVHIYFLIE
                     FDNKLLVMIQWGWNYFTRKRGARLITGKEVMQATESGYYAPADNRQLVSG"
     gene            19426..20670
                     /locus_tag="HC643_RS08800"
                     /old_locus_tag="DA73_0400008795"
     CDS             19426..20670
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017744533.1"
                     /locus_tag="HC643_RS08800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400008795"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_038091495.1"
                     /transl_table=11
                     /translation="MNKLWESLPVERQNSILEAIASSSPPGCLISPNTIEELAAVIAEA
                     HSKKQRILLCGSGSKLNWGGLAKGIDVVISTERINQLLEHAVGDLTVTVEAGMKFSHLQ
                     KILANSKQFLAIDPTSQESATIGGIVATADTGSLRQRYGSVRDQILGITFVRSDGKIAK
                     AGGRVVKNVAGYDLMKLFAGSFGTLGAIAQVTFRLYPFLEASATVVLVGDASAVSQAAD
                     TLRGSALTPTQSDLLSLQLVSGLGLGQGLGLMVRFQSIAESVKEQSNQLLEVGKQLGLR
                     GMLYSGTDEADLWLRLREQIHDVSHTPAITCKIGVLPTSSVEVLTRSELGWIHVASGLG
                     VLRFEGEKIEKVLEMRNLCQRNGGFVTVLVAPARVKESLDVWGYGGNALALMRRIKEQF
                     DSGYIFSPGRFVGGI"
     misc_feature    complement(19474..19488)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.04"
                     /tool="antismash"
     misc_feature    19475..19489
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.25"
                     /tool="antismash"
     misc_feature    20742..20761
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 21.47"
                     /tool="antismash"
ORIGIN
        1 acgattgttt tggttctttt ttcgggaaat ttaatcgatt tggtcgcacc aggcttaaat
       61 caattaccac agggaggtgc tgtaaaagcg atcgccatcc aacaacttca gattatggca
      121 ccaatggcaa tgcttgcggg gttgattggt attggctttg gcaccctcaa cgctgctaat
      181 ctattctggc tcccttctat cagcccatta ttttccagta ttaccgttat tatcggtttg
      241 ggtgttttat ggctgcagtt ggggagtaaa attacttctc ctgagtatgc tgtgctgggt
      301 ggaatggttt tagctggagg aaccttagca ggagctatat tgcaatgggt agtacaactt
      361 gttgctcaag cgcaagccgg aatgggtggt tttcgcctgc gatttaatat caatcagcct
      421 ggggtgggtg aggtgatgaa aatcatggga ccagccacca tttcctctgg tatgctgcaa
      481 attaatcttt gggttatttt attttttgct tctaatattc catcggcggc ggcggcgcta
      541 gcaaatgcca atcttttggt acaaacacca ttgggaatca tttctagtat gattttggtt
      601 cccctactac cagtcttctc ccgactggca gatcctaaag attggcacga tctcaaatta
      661 cgcattcgcc aaggaattat cttgtctgct tttactatgc tgcctttagg ggctttgatg
      721 atcgctttgg ctgtacccat tgtgcgtgtt atttacgaac ggggggcttt ccaaaaggat
      781 gaatctcaat tggtagcttc tctactgatt gcatatggta gcggaatgtt tgtctattta
      841 gcacgcgatg ttttggtcag agtcttttat gctttgggtg atggagatac accatttcgc
      901 gtcagcagtt ttaatatctt tctgaacgtt gtcttagctt acatttttat caatattcta
      961 aaactaggtg ctcccggttt ggtgttaact accgtcggag tcaatttcag ttctactgta
     1021 atgttgttat ttttgctaca tcgcaagctt cgtggattgc cttggttgga atggagtgta
     1081 cccattctgg gcatgacttt tggtagcgtg ctggctggtg cggctagcta tggaactctt
     1141 gagttttctc aaaggctttt gggtaaggat ggattgccaa ttcagttatt gcagctatct
     1201 gttgctgggt tagttggctt ggggattttt gccgcgatcg cagcttgtct gaaaatccct
     1261 gaggtgaacg tctttgtatc tcggttgcaa cagcgctttc taaagcgccg ctcgtaataa
     1321 attatctact aaaggtggtg cggcaagttg ccagtaccac tagtacatga aggcagaagt
     1381 acgtaggcag atggcagaag gcgcaacagc ttttaagata agctttttgt tgctgacaaa
     1441 tggttacctt atttacgcca acctgtacta gaaatttagg gatattattt tttatttgga
     1501 tcggcatttg tctgctagtg actactattt tagcgaaatt tacagacgat atgttcaccg
     1561 aactgggtgg aaaaaacttc acctacttgg gtaacctaag tgtacgaggg catatcttgt
     1621 taaaaagggg actctagtac tagaaagcat tgatatttaa tcaactctag ttacgaaaga
     1681 cctatgaaat ttacaaaatt agcaacttct gcacttgttt ttgcttctgt tattttttct
     1741 gctggaattg cctcagcaca gtcagttcca acacgcggta caagtgctaa ctacttgggt
     1801 gctggtgttg cggctggtgt aactaacggc ggacaagata atgacgcagc tacattgggt
     1861 ggtaatattc aaggacgatt tgctgttcca aaagcccctg tatcagttcg cggttctgtt
     1921 ctgttcggtg gcgatgcaac tgctgctatg ccaatagtca cttatgatgt accagttgct
     1981 aaagatacaa acgtttatgt tggtggtggt tactcctttg tgacggatga aggtaaaagc
     2041 actcccttag gaaataaaaa ttcacctgtt gtcacaattg gagctgagag agaaatcgct
     2101 aaaaacttcg tcttatacgg tgacgctaag tggggtattg atgcttatga aaacagttct
     2161 gctgatgccc ttagcattca atcaggtgta ggcttgcgct tctaatccaa gtactgccag
     2221 atccccatct cgatctggtg gctccgcata ttacctcgtt cccaggctcc gcctgggaat
     2281 gcctcctcta aaggctccgc ctagggtgtt caaacccgct ccatatattc agcacgtcgt
     2341 aacgccaaat tatataaagt ggtacaaggc gttaatatac aaaaatcacc ctacggcata
     2401 aagtgtatca aaaaggttta tgacaggttc gcttactacc tctacttggg agcatcccaa
     2461 atgtataaaa gtcgcaaatc taaaatacca tttttcaacc ccgatccaag ctggcgcgta
     2521 gcttggggag ccgttgatgc aaattatgaa gatatagctt ggcgagacga ccaagttact
     2581 gtcattgtac cgcgtacagc ttctggagtc ataacggaga aattagcgat cgctcgtgga
     2641 gaacaatttg ttgttgttgg tgatgtttgg ttaaccaacc aagtacaatt attagaaaat
     2701 ttaggagttg aaccaaatag ctttgcgcta agtcccctgc aactggttgc taatctttgg
     2761 gaacgatggg gtatgaaatg tctcaaccaa cttgagggga tgtttgctct agttatttgg
     2821 gatagagaaa aacaggtttt gtggtcaata cgcgatcgcg ttggtgctcg tactctctac
     2881 tacaccacca ctggttcggt tcgttggatt gcgcctaaat tgagaacttt agcactccat
     2941 cgttcatcgg atttggattt ggttgcgtta cgagattatc tctgttgcgc ctttgttccc
     3001 ggcgagagaa cgctttggca acaggtacgc gaactgcgcc ccggaactgt tttacaattg
     3061 cctgagtgta aggttcaagc gtattggcaa cttcaagaaa agattacagc aatagataaa
     3121 tctctagcat ggcatagcga tcgcctgcga caactgctag accaagttgt tcgagaatat
     3181 ttaccagcag aaaatgaacc tgttggcgtt tttctttctg gtggtttgga ctctagcagc
     3241 atcactgcaa tagccgcaaa attccatcat tccccagtcc acaccttctc cattcatttt
     3301 ggctcggaat gtcccaatga gttggaattt tccagccttg ttgcaaaata ttgccagaca
     3361 caacatcaca ttctggaaat tacctttcga gatatgtggg aacgcctacc ggaaacaatg
     3421 gcgtatttag atgaccccat cggcgatccg ctgactgttc ccaacctttt gctaggacga
     3481 ctggcgcgag aaagcgtgca ggtgctgtta aatggagagg gtggcgatcc ctgttttggt
     3541 ggtccaaaaa atcagcccat gcttattaat agtttatatg gctccgtcac caatcaagat
     3601 tcattacaag cttatttaat ttcctttcaa aaatgcgcgg ctgatttgcc acagctttta
     3661 aaaccagaaa tttggacagc agtacaaaaa acaccttggg tttttgaaga agatttatat
     3721 tctcaagcca gctatctcaa tcgtttgatg gcaatgaaca tcaaatttaa aggcgctgac
     3781 caaattctca ctaaagtcag taacttgact caagctgctc ttttgcaagc gcgttctcct
     3841 ctttttgacc agcgtgttgt agaattaagc atggaaattc ccccagaata caagctttct
     3901 ggagtggaag aaaaagccgt tcttaaaggg gcgatcgcag agcttttgcc tcctgcaatt
     3961 gttcatcgtc ctaaaagtgg gatgatggtt ccagtacagt taggatttcg taaatattgg
     4021 cagcgagaag ccaaaaattt attgctcagt cgtaatgctg cgatcgctcc ttatttaaac
     4081 cagttgccaa tccggaattg gttaaactat caaggagata cttggagtcg ttatggcgtc
     4141 aaactttggt tgcttgtgag tttagaaatt tggttgcagg tgaatcaaaa ataaaaaaat
     4201 cttgagaagt ttgatttttt ttcagtcata agggtcaaaa agaagattaa aaaattagaa
     4261 agcttttggc agtcctgctt gtttcaaaat tgcatttgct gtgtggcgag acttgataga
     4321 agcatctact acaaaccgcc tatctgtaat tgggctgtac caaatctcat ggtcgccctt
     4381 gccttgccgt tcaaaatagc aactaccttc tgaaagaatc ttttttaatt gagcagtaaa
     4441 cgatgcaccc atctatgaag ccacctctat caactcttga cggtggctga ttaattcaaa
     4501 gctgatagaa cccgcaaacc cagaagatac aatattattg agaagaataa gttctggtat
     4561 catttctctg agcttttgtg taagagcttc aattgtagaa gcctctgtta ccaacccagg
     4621 tatatcctca ctagtggcaa cccatacttt tgcttctgca tcccaaaagg cttgaacctt
     4681 aaatgtagtt tgtgtcatta tcaagttttt atgacggtag ttctagttta aaacaaatga
     4741 ccgagacttt aatccggagt agtattaagt tgtttcaaag tttgcattaa ccaaaacttt
     4801 gattaatata tatggaattg tcatttattg aaccaccctc actagtaaga atcaagctac
     4861 tatcatcact gtttaaagtt cgactgttgg ctatactctg gttaagaatt tgaattaatt
     4921 tttgcggact aaaggattcc aactccacaa agttaccagc ttccaaccag tccaattcat
     4981 ccgttgataa agtagcacga atttctggta aaagttgttt ggcagcctca gccgattcag
     5041 gagaagtttg aacgaacatt ctgcgatttg cagcaataat ttgacggggt agcaatccca
     5101 catcaataat tatgacatca ctctctccaa accattccgg tctggtacgg atctgattca
     5161 acaaagctat accagtgggg ctacaatcgt gcaacgcata cacttttaag tcagaattgc
     5221 gccgcagcat ttgcatggta gtatcaaaga tattttgagg atagccagtg atactgagaa
     5281 tggcacagtt attttcaaaa tgaaagttgt tggcaattaa catttgggca atttctgcac
     5341 tatcgcacac cactaatcta tcaaaactat atgcagtcac atcaggattg atagtcacag
     5401 gtgtattttg ttgttgggga gcaggtaaaa tcttatcaat tgaattgtta acccgtctcc
     5461 aagatgtcag ccactcctca agttggttat tgttaatcag aagtttttga ctgatagttg
     5521 tcgatcgccc tatttcgcca gttcctaggt aaatagctaa cattcctaag aatacactcc
     5581 ctacaaatgt acgaaaggaa ttgacaccta aactaaaaaa gatgcctgct atcaaagtga
     5641 tagctcccaa gattattaaa gtttttgcta atttcttacg ttgtgaataa gaatttttaa
     5701 ttgcttgtat ttgagcgaag aaaatgacta agagcaatgc ggacaatccc aaatactcaa
     5761 agaaataaaa acttgctatt acaaaaacta tccacaaaaa tacccatgag ccttgatttt
     5821 tattttgcag ttttttatta agactataaa aaaactgctt ttgtgtaaaa aaaagtgtat
     5881 catttgcaga aatatctgca atggctttag caaaaaaagg atcggtaaat ctcactccag
     5941 tcatactggt aggttcaaaa gtaaacggat gagagcagtt tttacaacgc ccgtaattgg
     6001 ctgtcctgtc tttcagttta ttatcagtgc cacattgaac gcatttcatg gtagattttt
     6061 gctcctaaag ttttaatttt tatttatgaa agagctgatt gttcagtaat acgctgtagt
     6121 cttcgcgttt gcgaattaaa cgatgcgtat ctttttctaa caacacctct gcaggtttag
     6181 gacgatgtaa aaagtgtgag gacatggcat aaccataagc accgacatct aaaacaccga
     6241 taatatcccc aatttctaat gctggtaaag aacagttttt gcctaaataa tcccgtgaat
     6301 aagtagtgtt tccacatata tctgtaaggt aaattttaga acttgcgaga tgtgcgggat
     6361 tgtcccgatt tttccacgcg acaatttccc gatatccgcc atgtactgta ggaacggaga
     6421 gattagcaac ggtggtatct accccaacaa tttgtttttc tgaatgccat ttcacggaaa
     6481 caactttggc taataaagtg gcgcatccag caattgctgc acgtccgggt tcgatgacta
     6541 actcaatatc ttttcctaaa tgacttattc tattgcttaa gtctgtaccg aacgtttccc
     6601 agttaaaagc tgcgctgcta tgatgatatg agtaaccaaa accaccccca aaatctagat
     6661 attcccaatc cggtaaaagt tctgccgttg ttataacctt atcaatgacg ttagtaaaag
     6721 cttctgtcgc attcgtaccc gtacctcggt aaaaatgtaa accgctcagt tttaatccta
     6781 cctgacgggt aagagcgatc gcatggggaa attcttctgg acgcacgcca atgcggctat
     6841 caccagttat ttcgggtagg ttgagacgca agccaaggcg gagtgaagga gtgaggaagt
     6901 gagggagtga gggagtaagg gagtgataga cttcgcagca cagttgcaat tgagcaacgc
     6961 tatctaaatt gagagttgtt acaccccaat ttaagacctg tttcatctcc tcggaattca
     7021 aattactccc actgtaaaca atttgttcgg gcgcaaaacc tgcttgcaat ccgagataaa
     7081 tgtctccagg agtattggca tgcagtcccc aacttttggc gcggaaaatt tgcagcagag
     7141 aaatatttcc attggtgacg ctagcaaagc gaaattgggt gcgaggatag gaaaaagcct
     7201 gggtgatgtg cctgatggtt tgctctaaga tatcagcttg gtaaacgtaa agcggcgaac
     7261 cataagtatt tagcaactct tgagctagtt ctaggggaaa aggaagatga gctgatttta
     7321 cgcttgccat tttttttgaa gtctccacag ctgttttgga agccaaaacg gatggtcaaa
     7381 agattgtttg ctggattctt caccaaaaac ctgttctcgc caaagttccc acacaatcaa
     7441 caaccacaaa ctttcaccaa tcaaacgacc ttgaatcgta gcacccaatt gacccgcagc
     7501 aatttgcgat gcgatataag gagaaaagca attttcggca cgaagtttgc ctggattcaa
     7561 ccatttgcca agctcatacc agaactcatt taaacaccaa gaggttaagg gaacccccat
     7621 accccgcttt tgtcgccaaa caatttctgg cggtagccaa ttttccacgg ctcgcttgag
     7681 gatatatttc tcgcacgctc cttgcaagca gagttctcca gaaacctgga atgtccattc
     7741 tgctaggggt aaatcgcaga aaggcgatcg cacaaacaac ttgtgagcaa atcctaaagc
     7801 tgttgcacgc ggatggatat tttgtgctcc ttttaacatc aggctggcac gccggagtcg
     7861 atgcaggatg gttttacagt aggtaggatc gagggcttct gcaatccagt cttctgggtg
     7921 tagattttgt atctgcttgt aaacatgcgg ctggtaaatt tgtgcttcat aaccccaaag
     7981 acggtggaaa gttcggagat attgttgtat aaatgtttct tgtcctgatg gattttctgt
     8041 ttggtaaacg cttgctgcta ttaaaggctt attcgtccaa cctgcaaata actggtcgcc
     8101 accttcgccg ttaaaaatca cctgagtttc ctgactggct ctttgtgcta aaagaaacaa
     8161 gggaaccgtt accccatccc cgaaaggtaa atcgagcgct cgtacagtcg gtagaatagc
     8221 tttctgaatt tgacgcgggc tggcatcaac ttttaccaaa ggaatttgca agtgctgggc
     8281 aacaatttcg gcatagggat attctggaac acctgcaccg ccaaaatcta gagtataagc
     8341 gatcgcattg actcctgctt gtactagcaa cgccgctaca acagaggaat ccaacccccc
     8401 agagagaaaa actccgactg gctcatcttt taagtcagaa atttgacgct caatgccttg
     8461 ttttaacaga gtttgcaatt gtttgacagc ggttgtttca tcttggagtt gaacgcttgc
     8521 ttcacaccat tccaataagc gttgagaaat cggggtgctg agcttgcgat cgtcaggttg
     8581 gctttgccaa actaactcag ttcccgcagg aactgcaaag acttgagtaa tgggtgtgag
     8641 gggattggga atatacgaaa aacaactata accgtataaa gcaggaatgc tcacttctgg
     8701 ctcgtcaaca accgctagca agagttgcag acgggatgca aaccaaataa cttgtccttg
     8761 ttgagcccag tataacggga ctcgcccaaa aggttctcgt cctaaaatta aacgattttt
     8821 tccctgtaaa tgtacccaaa tatcgggtaa aaatgagttg tcttgtaaat cagtcaatat
     8881 tcccgatgct gatagagcag ctattctttc tatgccatga cgctgaaaat aaattgatgg
     8941 gataaaatct tttgaaaaac cgatgcaagc aacattccaa ataggataat ggctctcgct
     9001 tggggaatcg agagaagata actgataaga attatgaccc gtttttttga cagcaccaag
     9061 gcttgtttct aattctcgtc tttcaccgta accccaatat ccaataaaat gcttgggttg
     9121 aatgatgcga tcgccctgct caacgttaac catactattt gacttgaaat tcggcttcgc
     9181 tgagttggcg attttggaga aacatctgca ccttccattg acctggagta gatgcagaac
     9241 ttagattata acgacactgg gtattccaga tggatttgtc aatttcacgg gtttgatagc
     9301 ggttttgttt gacaacttga ccgttagggt cgatccaatt gcaggacaaa tccaactttt
     9361 gatttaaagg tgcatctttt aacgtgacgc ggtaaaagat ttctgggttg ttctggcggg
     9421 cgatatctgt caagtcaccg ccattatctt gggtgagggt aatgcgatct gtttgggcaa
     9481 aaaccctcgc aagcacggaa ttctgctgtt gcatagcaaa caaggtacca gcaatgacta
     9541 ctattacagc tgcgatcgcc ccgatagcga tcgtgcgttg gcgtttttgc tgtacttcca
     9601 aagcttggcg acgccttact tgaacaagcg cttcatcaag caaatctggg gcgagaccca
     9661 attcttgtaa aatttcctta acttgttcgg gttcaatttc tgcttcccga cgtgtttgca
     9721 gcctttctac ttcagcgacg atctgtgtga gttgctcggt tgttagtttc tggctcatga
     9781 tatggcaatt ctcataaccc atagaaatta tgcactatgt taacttaggt tatgtagcag
     9841 tcttatttga gttataaaag ttattaaccg caaagacgca aagagcgtaa agaaaggaaa
     9901 gaagagattt tacaaatgat ttaggattgc tatagatgga gtaatagatt tgataatttt
     9961 tgaagttgaa ctgtagttaa ttgtggtatt catccaatcg ctagtactga cttcctccac
    10021 aaaccggaca ttctaaaagc ttatttaaaa tttgatgctg catcgataga gatgccaaat
    10081 tgaaagaaat taacttaccc gttaattgtt gatgctctcc ccaaataatc catttcgctg
    10141 tttccatcgc tatcaaattc agccctaact gaaagctaac tggaagaact gcaaaagaag
    10201 agagtaatga tggtgacatt ccttccctat gtatcgtttc agtttcacgt ttatttcgca
    10261 aatcttgagc aagacattcc caacaacccg ttcgccccgg aacaaacaga ggtcccaacc
    10321 aaatctccgt acctacaggt ttagctagca gccatggttt tctagtttct tctgcttctc
    10381 gattaaattc gtctaaaccc agttgtaagt agttatcggt cagaacaacc gtaaactctc
    10441 ccccctcacc tactggaatg gaaagggatt ccaaagctcg aacaaatgct tcaactccca
    10501 ctctcccaaa gctgattatc gaaaccctac tatcttgtag tttgcgaaaa gcattttcag
    10561 attctgcacc taagccattc cagaacgcag caacttgtgg agggagattt actgaagctt
    10621 cagaaagata tccttcactg tttaaacgaa ctagagcatt ttgaatttca aacagggaaa
    10681 cttcttcatt taactgctga aagatctctt ggacagtata acgaccattt aaaaacggag
    10741 ctaaaaggac gtataaacga ccaccgaggg cacattgccc ttgctcgctc agaaggtaca
    10801 caatatcggg ttctatcact ctaacgtggt agtgaggttt aaacattggt ttataaaaca
    10861 taatattatc taaatttatg tactggacat ataacattca atactgtaca actttcttgc
    10921 aaaaatagag tttctagaat tattttttaa acaactgata ctatttttct gtaaacccgt
    10981 gcttaatgtt tcttcctaaa cttaagtatt tgcagtataa tattcacttt caagtattga
    11041 cataatgact aaagacgaat agttgtctcc ttgcttgaca gcttctcgta aaacgccttc
    11101 ttccttaaag ccgcaggttt gataaacgta tctggcgcgt tggttgtgtt caaaaacgtc
    11161 caaccaaaga cgatgagctt tatactcatc aaaaatcatt ttgatgagta tgggtaaaac
    11221 ccttttaccg tatcctgatc ctggtttagt aacgacgatt cgagttaact caatactacg
    11281 attgagcgac tgtaaaccag acaagataac ataaccactt ggctgtcccg attcattttc
    11341 aatgatgaag tatcttttgt caggattggt aatatttttg ttgtgttcat ctcgactcca
    11401 aagggtgata aaagttgcat attcatccct cctttcttgt gagagtataa aatctatatc
    11461 atctatgttt gcttgccgta attgcattgc taaaatgaaa tcatttagac caatactatt
    11521 ttaaatagaa acccgtggga ataattgcac gtcccttgtt tcgttctgta gttgttcgga
    11581 ttcagtgcat tattgctttc tgtacttttt ggaactctag ccgaaaagca tcttggcact
    11641 cgtatggctt ctgaaactga ataacttgct atgaggatgt tttaaaagta gtggctgatg
    11701 tctccaaaac tttagatccc ccctagcccc cctaaaaagg gggggaaata ctcttaaatc
    11761 ccctttttta aggggtctct tgatacagcg ataaacttta caaacatcct ctaaacaaag
    11821 ttaaaaattt tacgtttcat atttgcaaat acttaaaaat tttttcaatt tgttttgggg
    11881 cttgcatctc ggtaaacagt cggatggctc gatcgaaatg aattctgctt tcttgtttct
    11941 tacctatttt agaaaaagtt aatcctaatt gaaagtcagc gatcgccaga tcgcatttgg
    12001 ctccgattct attcaaaagt tcgatagctt ctaaatgatt gtcaattgcc aattcaaatt
    12061 ttgcttgttg tcgataaatt tctgctatac cgcaaagcgt ttttgcttgg acttgcgtgt
    12121 agtggctttc ttcagcaaaa gttaaagcca tacggaacat ttcctccgct ttagcaaagt
    12181 ccttcaaatt aacatatgtt tgtcctaaaa tttgcatgaa ataagcaaat ctgccactag
    12241 gtttaacaag ttgttgtgtt gcgatcgctt gataagcttt atcagccagt acacgtgctt
    12301 cttctaaaat tcccaaataa gaattcacta gagccaaaca tacagttgct ttttctgccc
    12361 accgatgatg gtcggtatcc tgagctaagt caataacctg ttgaaataat tgggcagatg
    12421 catctagttc ccacaaatca attttataaa gaccaatgct cagtagagca tctacttcta
    12481 acattttgta atagtagaat ttgtgtttgt tttcccgtat tcttgataga gaatttattg
    12541 cccgatatgc tatgttaata gatttttcct gacattctat tgctgcgtgt actttcccaa
    12601 taatccagta gagatcgcct aaaatattat aaagttcgct gagattttta tctgacggaa
    12661 catttttaat aatgattgta atagctgcaa ttaaaggttg cagccatccc attcgatata
    12721 acgtacttcc taatggtaaa aattgttgcc attggttatt tctactttta agaatgactg
    12781 taccagccca ttcaaattcg tgaatttcta catagtgata gtaagcttct aaggcttgca
    12841 aagcatcttt aaatgtagtg attttttgta tgctctccgt ccaaaattct gctgctttac
    12901 ggttagttat ttcccattca tcacttatcc gcaagtgaga aataacctca gaacggatcg
    12961 ctggatgaag ccagtactca tctttactac actctactaa agaccgattt tttaaggaag
    13021 ttaaaatttg ttggtgctgg caaggtaaaa catcccataa taaactaaaa actccttctt
    13081 tgggaattct gggaacatct tgatagcggt aacatcccaa acgggaaagc aggcgatatg
    13141 ctagaggatc taaagcttgc aaacggttaa tttggctgac aactaaattt tttaaatcaa
    13201 ctacagccag tggttcagct tgatgttctc gccagtaggc aatggtatca ccatcaaaat
    13261 cctgccgaat tgaaccgcat agaataccca ttgctttggc atttcctcca taagcacggt
    13321 gcatactttg taaagtagcg aagtcaatag gtaattctct tttggtaaaa aattgctgcc
    13381 aagcggttag atccagtccg gggagacgat agtgctccac gttcacttca ggttcgcaaa
    13441 ggcgatcgcg acttgtaatt aatgtcacag attgcactct cgcgtctgct aaaacgcgta
    13501 agaattctac ataatttcgg tgcttggcaa taaaccgtcc ttgtctgtct agtgcgggtt
    13561 ccaaattatc aatcaaaact ccaacccgac aggtatggag tttccgcttc aatcgtccca
    13621 acgtcacccc aaattcaatt cccggttctt catcaaaatc ctgtttcaac cactcttcaa
    13681 tgacgtgttc cgccgccgtg atattttgcg tctcctttgc cataaggagt tccaagacca
    13741 aatcaaatcc ttgggtttgt aagtattcct gggctagagt tgttttacct actcctccct
    13801 caccttggat aacaatgact tttacacctc gattgactaa ggtattgagg tgagaaattg
    13861 cttctgttcg accgagaaaa tttacatttt cttgttttgt gatgaattct gctctaggtt
    13921 gctctttccc tatagtgaag ttttcagcaa agcgtgaggt atccagtaga ttcgagataa
    13981 cgctagtttt cttccaatat cgctccaagg tagcgcgaca attactttta gtaatcttct
    14041 gtctcaacgc tttggaaaga agtttccaca aatgagagcc aacatctttg gcatgtcctt
    14101 ccgtacaacc gtaagaatta gcgatttcca ggtattttcg accttgccaa acttgctgaa
    14161 gaataacttt ttgcagctcg ctcaaccgtt cgccggtttg agcaggaatt acagtttcta
    14221 accaagacag tactgcttcg gcgtccattg ccttacgacg aggtgatata tattcaaatt
    14281 gttgcgtcag ttcttgtcta gtctacacct ctactcttgg caatttctga taagtttctg
    14341 taaatctttt aagaaattga atgggtagca aattcagtga aagcccaaaa ctatatcttc
    14401 tttaggcacg ccttgttcaa gcagtagtgt agcgataccg acttcagtac catcatgctg
    14461 tatccaaatt ttactgtctt tgatctcaag gtgcatggtg catgcatgcg tttgattatt
    14521 atcgcgtcaa cttgcgtgtc ataaaatgta gcgatcgcga gagatatcta aaacagcttg
    14581 tgtctcgaat tcttcaagag caaattggta gttcagaact tgcccaagag cagtgtgaaa
    14641 ttaggagaca tttgaccccc caacaaagct cttaatttca actgcaattt tttcgcctgc
    14701 tcgttcagcc gctagcatct ctcatgattc taattcctcc aggttaatcc ccaaagctcc
    14761 taactgctct ggagtaagcg ctttcagttt ttcagccaat ttcagccgtt tttgctgttc
    14821 ttgttccttc atttgacgtt ctcgttctgc ttctttcaca gcttgttctg tatctgtgag
    14881 tatccagttg ccttctgaat cataccagcg caaccactga cgaataattc cttcaaactc
    14941 tccttgccac actcccaatc ctaaatttaa ctctgaaatc caaaaccgag gattctcagc
    15001 atctatagtt tgctcttggt agtgtcctcc ctccagtttg aacccacgca agcgattgct
    15061 atagcgacta aacactgcat agtatggtac tcgcaagata cgttcgtata catcccattt
    15121 tctcggcggc acttgtttca gagtttgccc attgctggac tctgatgcca aactcattgt
    15181 gctgacatct tctgtactcc tttctccgaa cattggttcc aattctgcat aatcgcccaa
    15241 atcttctttt tgtgtacctg gtgatagcag ttctaccact acaaaaggat tgactccttc
    15301 ttgccaaact acatagctag aacgcaagtc tttttcttca tacaatctcg gtacatctag
    15361 cactaaaaac caatccgggc gtttgtacca ctgagtatga cgtacatcat agtacagatt
    15421 taaatccgac cccgtaaata ttcgctcgta agaataattt gtcaatcgga ttgttcgact
    15481 gagcagctgc ggctgcaaat cgtgaaattc atcaggcaaa ccaggttcct ccgcatcttc
    15541 actgggtaga tcgtacatcg ttggtagtgt cagttttggc ggtaggggtg gatttgctgg
    15601 caggatgaag aagttagttg gctgcatggc aactcattca caaattgagc ttttctccga
    15661 ttgtatcttc tgtgagtacc cgactttttt cccgacttca accgactgac aaggaatctt
    15721 acagttgctt aagctattga gcaaagaggt aaaaatcaag gtgaaaacgg atgattaaca
    15781 ccctcagccc aatgtctcag gtaggactgg cttcttctcc cacgcactac tttcaacttc
    15841 tacaccgaat tcgttctctt gcagataatt atctttccat tgagaaactg tgcgatcgct
    15901 tgcaagattt acccattcag tttgaaaatc cacaaccccg tccctggaaa caaattgact
    15961 ggcaagctat ttcttcaaat caaattatag gcttagacag agaagtcttt ttgtccatct
    16021 tgagaggtgc aatggacacg gaagctccca ttcgggcata tactcaaacc agccgacaat
    16081 atttggaaaa cttacacccc cagctagcgc gatttgtggg cggaacagtc gatgaaacgg
    16141 gaaagttaat cgaacctgga ttgtgggaaa aagaagagcg ccagcacact cccgctttga
    16201 tgaaagtcta ttaccaatta acgggtgaga agattaccgc aactttccgc acggttagag
    16261 attatctccc tactgacgac ccacatgaag acttatatcg ccatggattg catcgtgttg
    16321 ccactgaata cggcgcaact tgtctctatt tatggttgat ggcgcataca acaggcgcac
    16381 ttcaagatgt tttggaggaa ttggttcagg atgaaatcaa tcacatgagt aaattctggg
    16441 ggtttggtgt ctgggctttt ccagatactt ctttaataaa ggtaggacac acgcttctga
    16501 aaacacgcca taaagactac aaacgcaaca gcctgatgcg tactttaaaa cgcatgatgg
    16561 gtacactgaa ctggagttct tggtctttga ccaacagaat aactctcttg tttgctttca
    16621 gctatgcaat gcgtcgtttg tggatttgga acgatcgctt aacgccaaag tatttacaag
    16681 gcttgttcga ccatacaacg ttactaactc ctaaccctta acaactaacc atgacttcaa
    16741 cactaccttt agatttagat ccccatcgct taccccaaca tgtcgctgtt attatggatg
    16801 gcaatggtcg atgggcaaac caacgaggat taccccgcat cgccggacac cgtcagggtg
    16861 caaaaaccct gaaagaattg ttgcgctgtt gtaaagattg gggaataaaa gcgctaacag
    16921 cttatgcctt ttctactgaa aactggcggc gaccccttga agaagtagat tttctcatgc
    16981 ttctgtttga aaaattgttg cgccaagaat tagctcaaat gcatcgcgaa ggggtgcgaa
    17041 tctcatttat tggggatttg tcaattctac ctacctcttt acaagctgag attgagcgtt
    17101 caatggcaga gactttgcac aatcaagcac ttcattttac tgttgcagtc aattatggca
    17161 gtcgcagtga gatcgcaaga gcttgtcgtc gaatagcaca actcgtgcaa cagggggaag
    17221 ttaacctgga agatgttgaa gaaaatttaa tcgaacaaac gctttacacc gcagggactc
    17281 ccgaacccga tttattgatt cgcacaagtg gtgaaatgcg attgagtaat tttctcctct
    17341 ggcaaatggc ttatacagaa ttgtatttta ctgatatttt ttggcccgat ttcgatcgct
    17401 cggcatttca tcaggcttta ctcagttacc aaagacgcga tcgtcgtttt ggtcaagtca
    17461 aaacttcttt gtctgcataa agtgtcactc ctagcccgtc cttacattgg ataggctggg
    17521 aatgttcact caatgtctat ttacaagaag tagatgaaat actttttact tagccacgat
    17581 ctaggtaaca aaagcagttt ttataccaac ttaagtctta tttctaacac cctaagatag
    17641 atgctctctg cttgaagaga ctgttacaaa tattaataat ttaattctgg aattttttat
    17701 gcttgccgat ccattggcta cagtagtttt gagggtgcat agtgtataaa aagattatca
    17761 ctaacaaatc tggaaaagtt catttaggca gtgtagtggt aactatagag attggcttgg
    17821 ggtttggctc gtacactcac aggataagtg cctaatggtg ttatttttgt gaccaatatt
    17881 attctgttta ccaattgact gtatcgtaaa aaacttttac atttcttaat atgtttgcgg
    17941 taagcagaac tactctaaca acaatgttga aaatttgtta agaaggatta caaaggatta
    18001 ccctaggaag taaatcttat gatgaacacc gttgatagcc agccacccca tcatgtagtt
    18061 atagtaggcg gaggatttgg gggtttatat gccgcaaaag cactgggacg tgctgatgta
    18121 aaagttactt taattgataa gcgcaatttt cacctatttc aaccattgtt ataccaagtg
    18181 gctactggta ctgtctcccc tgctgatatc tcctcacccc tacgttcgat tctcagtaag
    18241 agcaaaaata caaaagtgct gcttggagaa gtgaccgaca tcgatcctca agcacaagaa
    18301 gtgactttgg gcgaagaagc aatacactac gattccctga tccttgctac aggtgcaaaa
    18361 cactcttact ttgggaaaga tcaatgggaa gaatttgcac ctggtttaaa aacagtggaa
    18421 gatgcgattg aaatgcgccg tcggattttt atggcgtttg aagcggctga aaaggaaact
    18481 gaccctgaaa aacgccgagc ttggttaact tttgttattg ttggtggtgg tcctacaggt
    18541 gttgaactag caggtgcgat cgcagaactg gcttaccaca cgatgaaaga ggatttccgc
    18601 aatatcgata cgtctgaagc acaagttctt cttctagaag gaatggatcg cgttcttcct
    18661 ccttttgcat cagaattatc caaagaagca gaagcgtctc ttacacggtt aggtgtgagc
    18721 gtacagacaa aaacgctggt gacgaatata gaaggcgatc tgattactct aaagcaagga
    18781 gatgagttcc aacagattgc agccaaaaca gtgttgtggg cggctggtgt caaagcttct
    18841 cctctgggta agttgctagc agagcggaca ggatctgagt gcgatcgcgc tggaagagtg
    18901 attgttgagc cagatttgag tctcaaaggg ttttccaata tttttgtggt tggtgactta
    18961 gcacattttg cccatcagaa tggcaaaccc ctacctggtg ttgctcctgt cgccatgcag
    19021 gaaggacaat acgttgctca attaattcaa cagcgcatga aaggtaagac actgccacag
    19081 ttttcctata ctgacatggg tagcctagcg gtgatcggac aaaatgctgc ggttgtagac
    19141 ttaggttttg ccaaatttac aggttttata gcgtggttat tctggctggt tgttcacatt
    19201 tatttcttga ttgagtttga caacaagctc ttggtgatga ttcagtgggg ctggaactat
    19261 ttcacccgca agcgtggagc tagattgatt accgggaagg aagtcatgca agctactgag
    19321 agcgggtact acgcacctgc ggataacaga cagttggtta gtggttagtg gttggtggtt
    19381 agtggtactt tttaactact aaccactaac tactaactag taacaatgaa caaactttgg
    19441 gaaagtctac cagtcgagag gcaaaattct atcttggaag cgatcgcatc ctctagccct
    19501 cctggttgtc tcatttctcc caacacaatt gaagaactag cagcagtcat tgcagaagca
    19561 cacagtaaga agcagcgcat tttactttgc gggagtggta gcaaactcaa ctggggtggg
    19621 ttagctaagg gtatagatgt cgtaatcagt accgaacgga taaaccaact gctcgaacac
    19681 gcagttggtg atttgactgt tacagtggaa gcaggaatga aattttctca cctgcaaaaa
    19741 attttggcaa actccaaaca atttctggca attgacccga cttcacaaga gtcagcaact
    19801 attggtggta ttgttgctac tgctgatacg ggttctttaa gacagcgtta tggcagcgtg
    19861 cgggatcaaa tactgggtat aacttttgtt cgctctgatg gtaagattgc taaagctggg
    19921 ggacgagtgg tgaaaaatgt tgccgggtac gacttgatga agttgttcgc tggctcgttt
    19981 ggtactttag gtgcgatcgc tcaagttacg tttcgcttgt atcctttttt ggaagcatca
    20041 gctacggtcg tcttagttgg ggatgcatcg gctgtatctc aagccgctga tactttgcgg
    20101 ggttctgcgc tcacaccaac tcagtccgat ttactgtcgc ttcaattggt gtctgggttg
    20161 ggtttgggtc aaggattggg cttgatggtt cgttttcaaa gtatcgctga gagtgtgaaa
    20221 gaacagtcca atcaactttt ggaagttgga aagcaactgg gtctgcgggg gatgctttat
    20281 tcggggacgg atgaagcgga tttatggctg agattgcgag aacaaattca tgatgtttct
    20341 catacgcctg caattacctg caaaatagga gtattaccga cttcatctgt tgaggttttg
    20401 actcgctcgg agttgggttg gattcatgtt gcaagtggtt tgggggtatt gcggtttgag
    20461 ggtgaaaaga ttgagaaggt tttggagatg cggaatctgt gtcaaaggaa tggcgggttt
    20521 gtgactgttt tggtagcacc agcgagggtg aaggaaagtt tggatgtgtg gggttatggt
    20581 ggtaatgctt tggcgttaat gcgtcgaatt aaagaacagt ttgattctgg gtatattttt
    20641 agtcccggtc gttttgtggg tgggatttag gaaatttgaa ctgcaaagac gagccagtgc
    20701 ggcgtggtga atccagccct ggaggcgggt ttcccgcgac caccgggact agtgaacccg
    20761 gaggggggtt ccccctgtta aagcacctgg tgtcgcaaag ttcgcgaaga aagagagggg
    20821 agggtcataa gatcgtggaa gtttcggaag gttttttgga t
//
