LOCUS       NZ_JHEG04000001        20252 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1749601
            Orig. end                         :: 1769853
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20252
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="5"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20252
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20252
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10252](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10252
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(526..540)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(767..1042)
                     /locus_tag="HC643_RS07060"
                     /old_locus_tag="DA73_0400007060"
     CDS             complement(767..1042)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS07060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400007060"
                     /product="hypothetical protein"
                     /protein_id="WP_137986462.1"
                     /transl_table=11
                     /translation="MSYYEFDNHFWSPQIVCSYQSELPKPRKTHSKILVGLLTLLCLSI
                     WTPLVFQILVAVTNTHEEVSIKDLTQSWEKMSEREIFLFYRSSQQQ"
     gene            complement(1524..2219)
                     /locus_tag="HC643_RS07065"
                     /old_locus_tag="DA73_0400007065"
     CDS             complement(1524..2219)
                     /GO_function="GO:0018784 - (S)-2-haloacid dehalogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006805 - xenobiotic metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747928.1"
                     /locus_tag="HC643_RS07065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007065"
                     /product="haloacid dehalogenase type II"
                     /protein_id="WP_038090630.1"
                     /sec_met_domain="HAD_2 (E-value: 7.5e-16, bitscore: 57.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNLNQYEVLTFDCYGTLIDWETGVIKALQPILDAHQIQLNEDGI
                     LELFARFESQLEGGEYRQYKNILQGVVQKFGEHFDFTPSSVELTALADSVKHWLPFPDT
                     VEALHILKKRLKLAIISNVDDDLFAFTAKHLQVEFDSVITAEQVKSYKPSLQNFQVAIA
                     RLGIPSEKILHVAGSIYHDIVPAKALGLSTVWVNRRFGKEGLGATLAAVSNPDLEVPNL
                     KTLAEMIQL"
     gene            complement(2292..3023)
                     /locus_tag="HC643_RS07070"
                     /old_locus_tag="DA73_0400007070"
     CDS             complement(2292..3023)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (49-145). E-value: 1.2e-08. Score:
                     25.4. Matches aSDomain: nrpspksdomains_HC643_RS07070_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747929.1"
                     /locus_tag="HC643_RS07070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007070"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_038090631.1"
                     /transl_table=11
                     /translation="MSLDSIQDNKAFNDYEAFAEAYVSRTESNAYNAYYERPAMFSLLP
                     DVRYKRVLDAGCAGGVYAEWLVNHGADVVAIDISNKMIDLTRQRLQNRAQVYQADLNQP
                     LTFLRSNSFDIVLSSLTLHYIQDWESVFREFHRILSPKGLLQFSTHHPFMDFLLFEKEN
                     YFATELLEDSWEGYGGKPVRVRFYRRPLSAMTAALTKTGFAIEHIIEPHPTEECKRLYP
                     EAYERLTTKPGFLIFRACKQV"
     aSDomain        complement(2589..2876)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS07070_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.20E-08"
                     /label="HC643_RS07070_oMT.1"
                     /locus_tag="HC643_RS07070"
                     /protein_end="145"
                     /protein_start="49"
                     /score="25.4"
                     /tool="antismash"
                     /translation="KRVLDAGCAGGVYAEWLVNHGADVVAIDISNKMIDLTRQRLQNRA
                     QVYQADLNQPLTFLRSNSFDIVLSSLTLHYIQDWESVFREFHRILSPKGLL"
     misc_feature    complement(3621..3637)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.05"
                     /tool="antismash"
     misc_feature    complement(3629..3642)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.75"
                     /tool="antismash"
     misc_feature    3630..3644
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.65"
                     /tool="antismash"
     gene            3664..6159
                     /locus_tag="HC643_RS07075"
                     /old_locus_tag="DA73_0400007075"
     CDS             3664..6159
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013736.4"
                     /locus_tag="HC643_RS07075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007075"
                     /product="ATP-binding protein"
                     /protein_id="WP_162002267.1"
                     /transl_table=11
                     /translation="MSVLLGAVLGGLYYGKIRAERTAIKISEIRKIKMQARVIVGNFNL
                     VLSDLMVLSEQIEFQEILQGTNEQNSTLAEEFFSFSQHKKIYDKIRFLDTTGQEIVRVD
                     FNSDRPNIIPQKQLQFQLKRYWFYETLGLNKGEVFVSPLDLNIEGEKVEQPLKPIIRFG
                     TPVFDERGKKRGIIILNYFGKKLLDSFVQVSYGTPGQSMLLNADGYWLKGATKSDEWGF
                     MFLDRQNHTFGKVFPEVWKQVSQRESGQLQTSEGLFTYTTVYPLLEGQIPNTGSRQALT
                     SAKGQINPRSYYWKIVSQVPIEAFDLRSNGLLLELLYLYIGLVGATGIGSWILAKASVH
                     RQMTEIELTKSQARLLELAERENLLKRCLSSQIRNSLELDKILSTAVAEVHKLLQIERC
                     QFLWCYIEDKSSRFELSHEACRGDSLTPLGSSPIEKVEMLSQAIIQEKFLQLDNVLTDA
                     RLDSASKDFLQSLGLTSLVAVAIYTHSNRLGVLVCQQTKDVRIWSNNEVELILGVADQL
                     AIAIDQAELYNQSRAATEAATIQAEKLTKALLQLQQTQAQLIQTEKMSSLGQVVAGIAH
                     EINNPVNFIYGNLNHIKQDIQHLLELIKLYQNSYIIPTPEIQAYLESIDLDFIAEDLPK
                     MITSMKMGSDRIRQIVMSLRNFARLEEAEIKSVNIHEGIDSSLLILQHRLQEKSPKLQI
                     EIIKYYSNLPKVECYPGQLNQVFMNLLNNAIDAIEALLLMLPLSTNKQGQIVICTEMSD
                     SKNISVKIKDNGVGMNEEVKKRIFDPFFTTKPIGKGTGLGLSISYQIITEKHHGTIECL
                     SEQGKGTEFWIKLPVQQNG"
     misc_feature    6180..6194
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.29"
                     /tool="antismash"
     gene            6281..8815
                     /gene="ptsP"
                     /locus_tag="HC643_RS07080"
                     /old_locus_tag="DA73_0400007080"
     CDS             6281..8815
                     /EC_number="2.7.3.9"
                     /GO_function="GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA]"
                     /GO_process="GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene="ptsP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016866269.1"
                     /locus_tag="HC643_RS07080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007080"
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="WP_050046328.1"
                     /transl_table=11
                     /translation="MVGIVIVSHSKQLAEGVCELAAQMAQGKVPLSVAAGIDDPENPLG
                     TDPMQVYEAIVSVYSDEGVVILMDLGSALMSAEMAIEFLTSEQQQKVHLCEAPLVEGAV
                     AAAVAAASGSSVQQVMAEARGALTSKVTQLGISTSPSFASNQGQITKHQGQTTKEIHVT
                     IRNKLGLHARPAAKFVSTAARFQSQIVVSNLTRKTAAVRADSINQVATLVARQGHKLAI
                     AASGADADEALKALQELVDSNFGEQEDIPSPSLPPSLTHSLPPSPHHFLQGIPASGGIA
                     IAPIFSYTPVSIHVQKYHVDDVETEWQRLRVAIQVSKEEIQSLLSQACTQIGDAEAAIF
                     DAHLLFLEDPVLLEAVHQRIFQQHQNAEVAWQEVVEELVNNYRSFEDPYLQERVADIVD
                     VEQRVLRLLIGFQSHIRNSDSSRDNLNPSEPAILIASDLSPSETARLDRAKVLGICTTS
                     GSAISHSAIIARRLGIPAIVGLPEEVMRLSNGAIAAVDGDTGRMWVNPESEVLNALSAK
                     RDTQQAVRQEALATVFNRAVTRDGRRIDVFANITGIADIEEALRFGAEGVGLFRTEFLY
                     MERITPPSEEEQQLIYLSVAQQLGKRPLIIRTLDVGGDKPISYLNLLSENNSFLGWRGI
                     RYCLDNPEIFKPQLRAILKASPQHQMKIMFPMVATVEEIRAAKAILVEVQSELRQEGIP
                     FDEEMEVGIMVEVPSAVAIADKLATEVDFFSIGTNDLSQYVMAADRTHPLVANLVDAFH
                     PAVLRMIQQTVQAARTAGIWVGLCGELASDPLSTPLLLGLGLNEVSLNPRFIPAFKQAI
                     AQLTVAQAEAIATSALQQDSAQKVRALLAQAV"
     gene            complement(8862..9248)
                     /locus_tag="HC643_RS07085"
                     /old_locus_tag="DA73_0400007085"
     CDS             complement(8862..9248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016874544.1"
                     /locus_tag="HC643_RS07085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007085"
                     /product="hypothetical protein"
                     /protein_id="WP_038072980.1"
                     /transl_table=11
                     /translation="MKAVIGKVLLVSASLLALLAPQSARAQIVPQPWVSVGSKEGDITY
                     SVGARALDLGAELGVGPDGAVGVDVLKFISLPVISPYVGLGYYSEDKGVAFSGGVQTRA
                     TDNVFVGVGYNSVRGINGQLGIRF"
     gene            10001..10252
                     /locus_tag="HC643_RS07090"
                     /old_locus_tag="DA73_0400007090"
     CDS             10001..10252
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="HC643_RS07090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007090"
                     /product="PqqD family protein"
                     /protein_id="WP_038072981.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.4e-09,
                     bitscore: 36.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3e-07, bitscore: 29.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTFQSLTINKDGFAFDLLTGESFQLNRCGQMVLQRLRHGDTQEQ
                     IMLFLCGRFGISQNIAQRDITDFYQQLNALGLLTEENQ"
     aSDomain        10025..10240
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC643_RS07090_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="5.20E-12"
                     /identifier="RREFam002.1"
                     /label="HC643_RS07090"
                     /locus_tag="HC643_RS07090"
                     /protein_end="80"
                     /protein_start="8"
                     /score="36.6"
                     /tool="antismash"
                     /translation="INKDGFAFDLLTGESFQLNRCGQMVLQRLRHGDTQEQIMLFLCGR
                     FGISQNIAQRDITDFYQQLNALGLLTE"
     gene            10249..11289
                     /locus_tag="HC643_RS07095"
                     /old_locus_tag="DA73_0400007095"
     CDS             10249..11289
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HC643_RS07095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DA73_0400007095"
                     /product="carboxylate--amine ligase"
                     /protein_id="WP_038072984.1"
                     /transl_table=11
                     /translation="MKPFTIAITGINAVDNPGPGTGIARSLREDHQLPTHIIGLAYDVL
                     EPGLYMDWLFDRYYLMPYPSSEPEVLIERLQQIKQQVGLDCVIPNLDVELPLYIRCAKE
                     LESLGIRTYLPTREQFALRNKAKLSDVAAAFGVRTPQTLTLTSCQELHEAIATLGLPLM
                     IKGPYYKAYRVSSEGEAIQRFYQLAAEWGYPIIVQQIVSGTELNLVGIGDGKGSHFGLV
                     ATKKIAVTELGKIWSGVTIHHPGLLKATEAFLKHTRWKGPFELECIADLDGTIYLIEIN
                     PRFPAWTYFATGVGINLPARLVRAALGLPLSPSVSYEAGKLFMRYTYEIVTDATPLQTL
                     VTLGER"
     gene            11291..12664
                     /locus_tag="HC643_RS07100"
                     /old_locus_tag="DA73_0400007100"
     CDS             11291..12664
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014803.4"
                     /locus_tag="HC643_RS07100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007100"
                     /product="alanine racemase"
                     /protein_id="WP_038072988.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 2.5e-33, bitscore:
                     114.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.4e-10,
                     bitscore: 40.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNQYEKPVIQKLDSKFTNKFSGNNQSQCKVQTEIAGVAIDDLVQ
                     QFGSPLFVYSEQTLRRKFRTIRNTFTTRYPNVTFGWSYKTNYLKAICAILHQEGAMAEL
                     VSKMEYDKAKALSIPGNQIILNGPHKPFATLEAAVRDGVTINIDHLDEIEDLEAIATRL
                     NRTISVGIRLNLNAGIYPCWSRFGFNLESGQAMEAVRRMASGGKLRVNGLHSHIGTFIM
                     EPAAYARQVEKMVMFGYEVEQEFGWQMEYIDIGGGFPSRSRLKGTYHAAEVMLPSIEEY
                     ADAVCDALWAALKPGHMPKLIVESGRAVIDEAGTLIASVCGTKRLPDGTRAYVIDAGVN
                     LLFTSFWYRFDIALDRQVSGLYEPSVIYGPLCMNIDVIDETISLPPLSRGTRFVISTVG
                     AYNNTQWMQFIEYRPNVVLVTETGDVELIREAEDLSDLERREHLPSRLDLRKFAPTSL"
     gene            12661..14736
                     /locus_tag="HC643_RS07105"
                     /old_locus_tag="DA73_0400007105"
     CDS             12661..14736
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015204 - urea transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0071918 - urea transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015226.4"
                     /locus_tag="HC643_RS07105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007105"
                     /product="urea transporter"
                     /protein_id="WP_038072993.1"
                     /transl_table=11
                     /translation="MKISALQTLRHLVYAVCAATAEILFLRGVGVGALLLSAMLLQPSV
                     LVMGLTGVLAAVGFAKVAQLDVAYWKQGPFLFNPLLAGLGVGYLFQLSAASLFLAAAAG
                     ILAFTLTWTLSYVLHTFFLLPVLSLPFVTVSWTIHLAAFRFAGLQHAIVPAHAYSIGLP
                     VPLEGFLRTLGLIFFLPNVWVGMIVALLLLWNSRIQFLLAVFSYTFGTFIQGILTGTFA
                     YVYYDPATLNFILVALALGGFYLLPSPQSYILAALGVALAALLGQAVSVFWAAVALPVH
                     ALPYNVVTLMLLYLLGLVGHHLLARYPQSSPEKTLDYELTARQRYHGSTGRLLALPFTG
                     NWVVWQSFDGQWTHQGLWRYAYDFLIRDEGGLTYSDDGLKLTDYYAFQKPVLSPIRGSV
                     VLVVRDLPDCEIGHVDQDRNWGNYVLLYDERGFYVEISHFAQNSIAVNQGDRIERGALL
                     GRCGNSGYSPQPHIHIQVQLTPVIGAATVPFNFANFMVNGEFCSEGIPAKDAVVEPVTP
                     DRSLTQALTFALDSQLHFSLTRKGREIGQLRVTNRMAIDGSFYLDSGNAKLFYTRDENR
                     LMFHRLDGKDPRLALLFLAMPRLPLIRQIDRQWFDYLPISMVVTGLRLMLYQFCSSLYP
                     KLASAHYIGQWQSDGILIGTISIPKVARKIQTSAIFNRDNQLVKVTVGDRSLVRQQ"
     gene            15158..16711
                     /locus_tag="HC643_RS07110"
                     /old_locus_tag="DA73_0400007110"
     CDS             15158..16711
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0046930 - pore complex [Evidence IEA]"
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0033212 - iron import into cell [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033921.0"
                     /locus_tag="HC643_RS07110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007110"
                     /product="iron uptake porin"
                     /protein_id="WP_050046327.1"
                     /transl_table=11
                     /translation="MPKKVVNYLILHLTSLVSGLLLTNATLVTETQAVFNEQLEIAPMA
                     RVNSVSQLLDIGAKDWEFQAAQSLFERYGCTEGYFDKTYRGNQTLTRYEFASKLNVCIE
                     QINKLLTQSTVNLSQEEDLETWKKLQEIFAAELATLQSRVARLEMQTTTLQEQQFSATT
                     KLVGEVIFALTDEFNQPTNNNTVFQERARLNFQSSFTGKDRLHIRIASGNANIFNLTGY
                     GVEAIQTFNFGNTNNTISADWISYFFPIGKNIQGYVAAVGGVHYDYAPTVSSYVEGYGS
                     GKGSLSVFGQRNPIYLIGGGSGGGVTYSFSQNLLLSTGYLADSYNLFDGNYAASAQLTF
                     SPSNQFSIGLTYINAYRQFAIFDTGSNLASVGTNLANGGGFDVGTVPSKVNAYGAEFTY
                     RFNPRFTINGWFSYINAHFMNLGTGDIWTYALTFAFPDLGKKSNLGGIVVGVEPYLGNA
                     SQFAVNAKNDVPIHIEGFYQHQINSNISVTPGLIWILSPGQNSENRDSIICTLRTTFAF
                     "
     gene            16749..17030
                     /locus_tag="HC643_RS07115"
                     /old_locus_tag="DA73_0400007115"
     CDS             16749..17030
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016860680.1"
                     /locus_tag="HC643_RS07115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007115"
                     /product="DUF2087 domain-containing protein"
                     /protein_id="WP_038072994.1"
                     /transl_table=11
                     /translation="MNGSEDLKRYLDEQGRVKEWPSKRNRSRFQQLVLEYLANQFEIDS
                     IYSEKQVNQLLNQHHTFGDPALLRRELFERGLLDRKRDGSAYWRKIQN"
     gene            complement(17021..18499)
                     /locus_tag="HC643_RS07120"
                     /old_locus_tag="DA73_0400007120"
     CDS             complement(17021..18499)
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016860514.1"
                     /locus_tag="HC643_RS07120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007120"
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_038072995.1"
                     /sec_met_domain="Aldedh (E-value: 7.2e-144, bitscore:
                     478.6, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKAIALPNYINNQWCTSNATEYLDVINPATAEVLARVPLSLASE
                     VEQAVQAASEAFGNWRRTPPTERVQYLFKLKNLLEEHFEDLARTITLECGKTLAESKGE
                     MRRAIENVEVACGIPMMMQGTNLEDIARGIDEMMIRQPLGVCAVIAPFNFPGMIPFWFL
                     PYAIACGNTYIVKPSEKVPLTMQKVFQLLEKTGLPQGVVNLVNGAKEVVDAILDHPKIR
                     AISFVGSTPVAKYIYSRGATNGKRVQCQGGAKNPLIVLPDADLEMTTRIAADSAFGCAG
                     QRCLAASIAVTVGEARRSFTEAIAETAQKRAVGSGLDPGIEMGPVITAQSKARIEGLIQ
                     QGADEGATVLVDGRSPNIPSYERGYFVRPTILQNVDPSGDIARTEIFGPVLSLIHVETI
                     EQAIALVNGGQYGNMACLFTSSGAAARKFRYEAEAGNIGINIGVAAPMAFFPFSGWKES
                     FFGDLHGQSNHAVEFFTQTKVVVERWPSNWSRQF"
     misc_feature    18841..18852
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 20.33"
                     /tool="antismash"
     gene            18871..19338
                     /gene="infC"
                     /locus_tag="HC643_RS07125"
                     /old_locus_tag="DA73_0400007125"
     CDS             18871..19338
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="infC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019488884.1"
                     /locus_tag="HC643_RS07125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400007125"
                     /product="translation initiation factor IF-3"
                     /protein_id="WP_272900264.1"
                     /transl_table=11
                     /translation="MNSQIKSPQVFLIDHENNNRGLTDTREALQLAESVDLDLVVVSES
                     KDAPVAKILNYGKLQYQKKKRQTQSARPTVKEVRLRPNIGLADYNLRISQASQWLSKGD
                     SVKFMIRLRGRENQYRSNAGELLDRIVADLSSVGKVQSLDKRSLIVQVIPA"
     misc_feature    complement(19510..19523)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.47"
                     /tool="antismash"
ORIGIN
        1 cccgtcagtt ttatctacgg aaatatcact cacgctattg aatatactca agacttacta
       61 catttattgc agtgctacca acaagaatac cccaacccga cacccaactt agcaacagaa
      121 attgaagcaa ttgaattcga ttttttggta gaagacttac ctaaactcct tcattctatg
      181 aaaatgggcg ctaaccgaat tcgagaaatt gttcgctctc tccgcacatt ctcacgtttg
      241 gatgaagccg aagttaaaga ggtagatatt catgagggta ttgatacaac cttgatgatt
      301 ttacaaaacc gcctgaaagc caaaccaaat tgcccagaaa ttcaaattat taaggaatat
      361 ggtaaattac ctctggttga atgttatgcc ggacaactca accaagtctt tatgaacatt
      421 ttggtgaatg ctattgatac gctagatgaa tgttgtccaa acttcaaaca tcaagtcggg
      481 acaattacta ttcgtactca tttaacaaat cccgatacaa tttctatcca cattattgat
      541 aatggcttgg gtatgagtga ggcagttaaa agccgtttat ttgacccctt ttttacaact
      601 aaacctgtcg gtaagggtac gggtctgggc ttatctatca gttaccaaat tgtcgttgat
      661 aaacatcaag gtactctcaa atgttactct actccaggtc agggaacaag atttgaaatt
      721 atgattccac gccaacagaa acagcagcaa aagtcataag tgtcagtcat tgttgctgtg
      781 aagagcgata gaaaagaaag atctctcgct ctgacatttt ctcccaagat tgcgtgagat
      841 ctttaatact tacctcttca tgagtattag tcacagcaac gagaatctga aataccaaag
      901 gagtccatat agaaagacaa agtaatgtca aaagccctac aagtatttta gagtgagttt
      961 ttcttggctt tggtagctcc gattgatagc tacaaactat ctggggagac caaaaatgat
     1021 tatcaaattc gtagtaactc atatctgtac cctctgttag cgtttctatt atttcagtat
     1081 gttcaataaa ctcaatcgaa tttaatacta atagtattaa aaacaaaata gatgaaagct
     1141 gaccaaagtt gtattccaaa aaataacttt ggaagttaac ttttcgggaa aactgtcaat
     1201 taccaacaat agccggtaac tactctctgt tcggttacaa tcggaaaatg gtacgattca
     1261 gttagccgca cccatcgatc gcatcacatg gcgctaggag tgctcggaac attgctctct
     1321 aagttagaga gcaaaagtga agaacttgtg gagaagcaat ttattacgca agaaaataag
     1381 ctctggcaat tgccagagca acaccactcc ttgctaatgt gtgtatctaa gtttactctg
     1441 aaaatcgaaa aaatgaaatc ggtgtttttg ctgtttttgg cttgcagact cgttttaaca
     1501 aaataataat atttctgacg ttgttagagt tgtatcattt cagccaaagt ttttaaattg
     1561 gggacttcta aatctgggtt gcttacagca gctagagtcg cacccaaacc ttctttaccg
     1621 aacctgcgat tcacccacac tgtcgatagc cctaaagcct tggcaggaac aatatcatgg
     1681 taaatgctac cagcaacgtg tagaattttt tcagaaggaa tgccaaggcg ggcgatcgca
     1741 acttgaaagt tttgcaaaga aggcttgtaa cttttcactt gttcggcagt gatgactgaa
     1801 tcaaactcaa cctgtaaatg ctttgctgta aaggcaaaca aatcatcatc aacattagaa
     1861 ataattgcca acttcaatcg ctttttcaga atgtggaggg cttcaacagt atctgggaaa
     1921 ggtagccagt gtttgacaga gtcagcaagt gcggttaact caacagaaga aggtgtaaag
     1981 tcaaagtgtt cgccaaactt ctgcacaact ccctggagaa tatttttgta ctggcgatac
     2041 tctccccctt cgagttgaga ttcaaaacgc gcaaataatt ctagaattcc atcctcattc
     2101 agttgaattt gatgggcatc cagaataggt tgcagtgctt ttatgacccc tgtttcccaa
     2161 tcaataagag ttccatagca atcaaaagtt aagacttcgt actgattcaa gttcatcatg
     2221 agaattttgg agttgagatt ttgaagtttg gactttagat tcggaattaa gcgaagcttt
     2281 ttcctgtagt attaaacctg cttgcaagca cgaaagatga gaaacccagg ttttgtcgtc
     2341 aacctttcat aagcttcggg gtaaagccgc ttgcactcct ctgtcggatg tggctcaata
     2401 atgtgttcta tagcaaatcc cgtcttggtg agtgctgcag tcattgcgct gagggggcgg
     2461 cggtaaaaac gcacccgcac tggtttaccg ccgtaccctt cccatgaatc ttctagtaac
     2521 tccgtggcaa agtagttttc cttttcaaaa agaagaaaat ccataaacgg atggtgtgtg
     2581 gaaaactgta gcaatccttt gggtgataga atgcggtgaa actccctaaa aacgctttcc
     2641 caatcttgaa tgtagtgaag ggttaaggaa ctcaggacaa tatcaaagga attgctacgc
     2701 aaaaaagtga ggggttggtt taaatcggct tggtaaactt gagcgcgatt ttgaagtctt
     2761 tgtcttgtta agtctatcat tttgttactg atgtcaattg caacaacatc agcaccatga
     2821 tttaccaacc attctgcata cacgcctccc gcacagccag catctaagac tcgcttgtac
     2881 ctgacatccg gtaacaaaga gaacatagca ggtctttcat aataagcatt gtaagcattg
     2941 gactcagtac ggctgacata tgcttctgca aatgcttcat agtcattaaa cgccttgtta
     3001 tcctgtatgc tatctagact cataatcttt tccctatttg ctacagataa ggctagcagt
     3061 tagcgtttcg ggtttttcag aattccgtgt tctagctgta aatttttgca acaaatattt
     3121 tgcgatctag cacccactca atcgctcgtt gtgagaaaca atgcgtatgg gtgctggcgt
     3181 accgcctatc gctgttatct tcaactcgga ggctaaagca cgatctggca tcggtccctt
     3241 ttcaaaatag cctgtgcagt gaggatagcc cctaatttat ctgggaaagg cagagggcag
     3301 agggcagagg gcagaaggga ggaataagta ttaaaggtaa caagtaatcc cctctattcc
     3361 gtctgacctc tgccaaaggg aacccctaag ccccccttaa aaaggggact ttgcataagt
     3421 cctatatttg atgattttct ttctataaga aaaatcttta tatgtcaacc aacgcattta
     3481 ttgcggatta tttggattca gcatggcagt gaggaagttg cgatcgagca acacaattgt
     3541 taagttacct gaattcctgg gaaccatata tctgacactt gctaggaatc gtcatatatt
     3601 aaaatgccgt tacaaaacca tgcacaagtt ttattcaaaa aatttttaat agtttttttg
     3661 ccaatgtccg ttttgcttgg tgccgtactg gggggtctct attacggaaa aatccgggcg
     3721 gagagaactg ctataaaaat tagtgaaatc cgcaagataa aaatgcaagc tagagtcata
     3781 gtaggaaact ttaacttggt gctctcggat ttgatggttc tgtcagaaca aatagaattc
     3841 caggaaatct tgcaaggaac taatgaacaa aactcaacac tcgctgaaga atttttctct
     3901 ttttcacaac ataaaaaaat ttacgacaaa attcgttttt tggataccac aggtcaggaa
     3961 attgttagag tagattttaa cagcgatcgc ccaaatataa ttcctcaaaa acaattacaa
     4021 tttcaactaa agcgctactg gttttatgag actttaggtc taaacaaagg agaagtgttt
     4081 gtctctccct tggacttaaa tattgaagga gaaaaagttg agcaaccact caagccgata
     4141 attcgctttg gaactccagt ttttgacgag cggggtaaaa aacggggtat tattatcctc
     4201 aattattttg gtaaaaagct gcttgactcg tttgtacaag tgagctatgg gacacccggt
     4261 cagtcaatgc ttctgaatgc tgatggatac tggttgaagg gagcaacaaa gtctgatgag
     4321 tggggattta tgtttctcga tcgtcaaaac cacacctttg gcaaagtgtt tcctgaagta
     4381 tggaagcaag tttctcaacg agaatccgga caattacaaa cttctgaagg attgtttact
     4441 tacacaacag tttatccatt attagaaggg caaataccaa acacgggatc gagacaggct
     4501 ttgacatccg ctaagggtca aataaatcct cgttcttact actggaagat tgtctcgcaa
     4561 gtaccgatag aagctttcga tcttaggtcc aatggattac ttcttgaatt actctatctt
     4621 tatataggat tggtaggagc aacgggaatt ggttcttgga tattagcaaa agcaagtgtc
     4681 caccgtcaga tgactgaaat agaattaacc aaatctcaag ctcgcttgct agaacttgcc
     4741 gaacgagaaa atttgttaaa aagatgtctg tcaagccaaa ttcgtaactc tctagaactc
     4801 gataaaattc ttagcacggc agttgctgaa gttcacaagc tcctccaaat agagcgttgc
     4861 caatttttgt ggtgttatat agaagataaa tctagccgat ttgaactgag tcatgaggct
     4921 tgtcgtgggg attcgttaac cccccttggg tcttctccta ttgaaaaagt tgaaatgtta
     4981 agccaagcaa ttattcaaga aaagtttctg caattggata atgttttgac agatgcacgt
     5041 ttggatagcg ctagcaagga ctttttacaa agtttgggct tgacttcttt agtagcagtg
     5101 gcaatttaca ctcattccaa tcggttggga gtgcttgttt gccaacaaac gaaagatgtc
     5161 cgtatatgga gcaacaatga agttgaacta attttgggag tggcagatca attagcgatc
     5221 gcgattgacc aagcggagtt atataaccaa agccgtgctg ctacagaagc tgctactatc
     5281 caagctgaaa aacttacaaa agctttactt caactacaac aaacccaagc ccaactgatt
     5341 cagactgaaa aaatgtctag tttgggtcaa gttgtggctg ggatagcgca tgaaattaat
     5401 aaccccgtta actttattta tggtaactta aatcatatca aacaagatat acaacatttg
     5461 ctagaactca taaaacttta tcaaaactct tatattattc ccactcctga aatacaagct
     5521 tatcttgaaa gtatagatct agattttatc gcagaagatt taccaaaaat gataacttcc
     5581 atgaaaatgg gttcggaccg cattcgtcaa attgtcatgt ccttgcgtaa ctttgctcga
     5641 ctagaagaag cagaaataaa gtctgtcaat attcatgaag gaatagatag ttctctgttg
     5701 atattgcaac atcgtcttca agaaaaaagt cccaagcttc aaattgaaat tattaaatat
     5761 tatagtaatc tacccaaggt agaatgctat cccggacaac tcaatcaagt ttttatgaat
     5821 ttgctcaata atgctattga tgctatagaa gcattattgt taatgctacc tttatccacg
     5881 aacaagcaag gacaaattgt tatttgtact gaaatgtctg actccaaaaa tatttctgta
     5941 aaaatcaaag ataatggagt tggtatgaac gaggaagtca aaaaaagaat tttcgatcct
     6001 ttctttacaa ctaaacccat aggcaaagga actggattgg gtttatctat cagttaccag
     6061 attattacag aaaaacatca cggaactatt gagtgtctat cggaacaggg aaagggtaca
     6121 gagttttgga ttaaacttcc ggtgcaacaa aatggttaat aataaggaat attacatcag
     6181 gaagtgatgt tacagttttt taatgcgtct tataactctt tctgctttaa tctctgtagg
     6241 tggttaggtt aaagctatta ggagagttga cggagttgcc gtggttggaa ttgtcattgt
     6301 ctctcatagt aaacaactcg cagaaggagt ctgcgaacta gcagcacaga tggctcaggg
     6361 taaagtcccc ctatctgtgg ctgcaggaat tgacgatcca gagaatccgc taggtacaga
     6421 ccccatgcag gtttatgagg cgatcgtctc cgtttacagt gatgaaggtg tcgtcatttt
     6481 aatggatctg ggaagcgctt tgatgagtgc agaaatggcg atcgagtttc tcactagcga
     6541 acagcaacaa aaagtccatt tgtgtgaagc cccacttgtt gaaggagcag tcgcagccgc
     6601 agtcgcagcc gcatcaggca gcagtgtaca gcaagtgatg gctgaggcaa ggggggcttt
     6661 gacgtcaaaa gtgactcaat tgggtataag tactagtcca tcatttgcca gcaaccaagg
     6721 tcaaattaca aaacatcaag gacaaaccac aaaagaaata cacgtaacta tccgtaataa
     6781 attgggattg catgcccgcc cagccgctaa atttgtctca acagcagctc gttttcaatc
     6841 tcagattgtt gtatccaatt taactcgaaa aacggcagca gtacgcgctg acagtatcaa
     6901 ccaagttgcc acattggttg cacgtcaggg acataaatta gcgatcgcag ccagtggtgc
     6961 tgatgcagat gaagcactca aagcattaca agaacttgtt gacagtaatt tcggcgaaca
     7021 agaagatatc ccctctccct ccctccctcc ctccctcact cactcactcc ctccctcccc
     7081 ccatcacttc ctacaaggaa tcccagcctc tggtggaatt gctattgcac caatttttag
     7141 ttatactcca gtatccattc acgttcagaa ataccacgta gatgatgtag aaactgaatg
     7201 gcagcgtttg cgggtcgcaa ttcaagtttc aaaagaagaa attcaatcgc tgctttcaca
     7261 agcgtgtact caaattggtg atgcagaagc tgcaatcttt gatgcccatc tgctgttttt
     7321 agaagacccc gtactgttag aggcggttca ccaacgcatc tttcaacagc accaaaatgc
     7381 agaagttgct tggcaagaag ttgttgaaga actcgtaaat aactaccgtt cttttgaaga
     7441 cccctactta caagagcgag ttgcagatat agtagacgta gagcaaagag tgttgcgttt
     7501 gctgattgga tttcaatctc atattagaaa ttctgattcc tctcgagata atttgaatcc
     7561 ttcagaacca gctattttga ttgcttcaga tctaagccct tcggagacag ctagattaga
     7621 ccgggcaaaa gtgcttggca tctgcacgac ttctggcagt gctatttctc acagtgctat
     7681 catagcccga agattgggta ttccggcaat tgttggttta ccagaagaag ttatgcgttt
     7741 aagcaacggt gcgatcgcag cagttgatgg cgatactggt aggatgtggg tgaatccaga
     7801 atcggaagtt ttgaatgcac tatccgcaaa acgcgataca cagcaagctg ttcgccagga
     7861 agcactagca acagtattca atcgagcagt gacacgggat ggaagacgga ttgatgtgtt
     7921 cgctaatata acaggcatag cagatataga agaagcatta agatttgggg cagaaggagt
     7981 cgggttgttt cgcaccgagt tcctttatat ggaacgaatt acccctcctt ctgaagaaga
     8041 acagcaattg atttatttga gtgtagccca gcaactcggc aagcgtccgt tgattattcg
     8101 gactttagat gtaggcggag ataagccaat ttcttattta aatttgctat ctgaaaataa
     8161 ttccttttta ggttggcgtg gaattcgcta ttgtctcgat aatcctgaga tttttaaacc
     8221 tcagttacgg gcgattttaa aagccagtcc ccaacatcaa atgaaaatta tgtttccgat
     8281 ggttgctact gtggaagaaa tacgggcagc gaaggcaatt ctggtagaag tacagagtga
     8341 attacgtcaa gaaggcattc cctttgatga agaaatggaa gtgggcatta tggtagaagt
     8401 tccttcagct gttgcgatcg cggataaact agccactgaa gttgactttt ttagtattgg
     8461 aaccaacgac ctcagccagt atgttatggc agccgatcgc acgcatccac tcgtagccaa
     8521 cttagtagat gccttccacc ccgcagtctt gcgaatgatt caacaaaccg tccaagcagc
     8581 acgtacagcc gggatttggg tagggttgtg tggggaactc gcatcagatc cactctctac
     8641 accgctccta ctaggattgg ggctgaatga ggtcagcctg aatcctcggt ttattccggc
     8701 atttaagcaa gcgatcgctc aattgactgt ggcgcaagca gaagcgatcg caacttctgc
     8761 attgcaacaa gattccgcac aaaaggtcag agcgttactc gcacaagcgg tataacttta
     8821 aaacttcttt attccaaagc cttctgccct ctgccctctt tttaaaatct aattcccaat
     8881 tgtccgttga ttcctcgcac ggaattgtag ccaacaccga caaaaacgtt gtcagttgcc
     8941 cttgtttgaa ctccaccaga aaaagcaacg cccttatctt ccgaatagta ccccaatcct
     9001 acatatggtg aaattacggg taaagaaata aacttaagta catctacccc aacagcacca
     9061 tcaggaccaa ctcccaattc agcccctaaa tccaaagccc ttgcaccaac agaataagta
     9121 atatcacctt ctttactacc tactgacacc cagggctgtg gtactatctg agcgcgagca
     9181 ctttgtggag ctaataaagc taacaaactc gctgatacta acaatacttt tccaataact
     9241 gctttcatat ttcactcctt cactttttgc caatttgctc tgaacactaa ttctcagtca
     9301 gtactgacag cagttagtct gcacgctgcc acgaactaag gtgtgtccat tatgactaac
     9361 aaaagacgga attctgtatg ggcgtgtgcc cgatttgtga aaaatagttc tttaaagcaa
     9421 ctactgaagt gtatttactg gtataggtat ttattaaggt atttatgaat acttttaagg
     9481 taattcaagc aagttagaga aaatattgag ccaaaaaaat cctttatctt aagtgtatgc
     9541 ggaaaaagct aacgtttaag gtcgttaaga gcagattttt cttatatttc atgagtaaaa
     9601 ttacttaaaa tttagcccaa ataggaaaaa agtactatac ctaagtagta ctttttaacg
     9661 agttttagaa aactagattc ggtacttttt tctcatgttg attgagagta taaattttta
     9721 tgattttggt gtcgaacaca aaaactttac aacttcttga caaattcttg acaagttaga
     9781 tagccaactt gcaggaaatg tttggaaatg cggggatcat cgttgaatag gtgtgtcaat
     9841 tgactctagg ttgtcaaatc ccagactctt tgaaaagtcg gggagctaaa ccaacttaac
     9901 ccatcaaaat taatgtgtat cgccaaatat gcgtgattga ggaaagatcg acaaaaatct
     9961 tttgtcctca ataagttttt gcaacctaaa taaggaacaa atgtcaacat ttcaatcact
    10021 aacaattaat aaagacggct ttgcttttga cttacttaca ggtgaaagct ttcaattaaa
    10081 ccgctgcggt caaatggttt tgcagcgctt gcgacacggt gacacccaag aacaaattat
    10141 gctatttctc tgcgggcggt ttggcatttc tcaaaacata gcacagcgag atattacaga
    10201 cttctaccag caactgaatg ctctgggact actcacagag gaaaatcaat gaaacctttt
    10261 acaatcgcta ttacaggcat taatgcagtt gataatcccg gaccgggtac aggcattgct
    10321 cgcagcctgc gtgaagacca ccagttaccc actcatatca ttgggcttgc ctacgatgta
    10381 ctggaaccgg ggctatatat ggattggctg ttcgatcgct attatctcat gccttatccc
    10441 tcctcagagc ctgaagttct gattgagcga ttgcagcaaa tcaaacagca agttggtttg
    10501 gattgcgtga ttcctaacct agatgtagaa ttgccgcttt atattcggtg tgcgaaagaa
    10561 ttggagtcgt taggtattcg gacttatttg cctacacgag agcaattcgc tttacgcaac
    10621 aaggcaaagc tgagcgatgt agcagcagca tttggtgttc ggacaccgca aacattaaca
    10681 ctcacttcgt gccaagaact tcatgaggcg atcgcaacat taggattgcc attgatgatt
    10741 aagggcccat attacaaagc ctaccgagtg tcaagcgaag gggaagccat acaacgcttt
    10801 taccagctag cagcggaatg gggctatccc atcatcgtgc agcagattgt cagcggtacc
    10861 gagttgaacc tagtggggat tggagatggt aaagggagcc attttggttt ggtcgcaacc
    10921 aagaaaattg ctgtaactga acttggcaaa atctggagcg gtgtgactat ccatcaccct
    10981 ggtttactaa aagcaacgga agcatttcta aagcataccc gttggaaagg tcccttcgag
    11041 ttagaatgta tcgccgatct tgatggcaca atttatctca tcgaaattaa tccacgcttt
    11101 ccagcatgga cttactttgc aactggggtg ggcattaatc ttccagcacg cctggtaaga
    11161 gcagccctcg gattgccctt atccccctca gtttcttatg aagcgggtaa attgtttatg
    11221 cgctacacct acgaaattgt aacggacgca acccctctac aaactctagt cactttagga
    11281 gaacgataac atggtcaatc agtacgaaaa acccgtgatt caaaaactcg atagcaaatt
    11341 cacgaacaaa ttttcaggaa acaaccaatc gcagtgcaaa gttcaaacag agattgcagg
    11401 cgttgcgatc gacgatctag tccaacagtt tggctctccg ttgtttgttt attccgaaca
    11461 gacactgcgt cgaaagttcc gcactatccg caatacattt accactcgtt atccaaatgt
    11521 aacctttggc tggtcttaca aaaccaatta tttgaaagcc atttgcgcta tcttacatca
    11581 ggaaggggcg atggcggaat tggtatccaa aatggaatac gacaaagcaa aagcactctc
    11641 gattccagga aaccaaatta ttctcaatgg accgcacaaa ccatttgcca ctctagaagc
    11701 agccgtgcgt gatggagtta ccatcaatat cgatcaccta gatgaaattg aagatttaga
    11761 agcgatcgcc acccgcctca atcgaactat ttcagtgggt atccgactta atttgaatgc
    11821 tggaatttat ccttgctggt cgcgctttgg cttcaatcta gaatccggtc aagccatgga
    11881 agctgttcgg cgtatggcca gtggtggcaa attacgagtg aacggtttac acagccatat
    11941 tggaactttt attatggaac ccgcagccta tgctcgccag gttgagaaaa tggtgatgtt
    12001 tggctatgag gtggagcaag agttcggttg gcaaatggaa tatattgaca ttggcggtgg
    12061 ctttccgtct cgcagccgtt tgaaaggtac gtatcatgcg gcagaggtta tgttgccgtc
    12121 tattgaagaa tatgcagacg ctgtttgtga tgctctatgg gcggctttaa aaccagggca
    12181 tatgccaaaa ctgatcgttg aatctggtcg ggcggtgatt gatgaagcgg gaacgctaat
    12241 tgcaagtgtt tgcggtacta agagactgcc tgatggtact cgtgcctatg tgatagatgc
    12301 tggtgtgaat ctcctgttca caagcttttg gtatcgcttt gatattgccc tcgatcgcca
    12361 ggtttcgggt ctttacgagc catcggtcat atatggtccg ttatgtatga atattgatgt
    12421 tattgatgaa acaatttcat tacctccact ctcacgcggt acccgatttg ttatttccac
    12481 tgtaggtgca tacaacaaca cacaatggat gcaattcatt gaataccgcc ctaatgtggt
    12541 gttggtgaca gagacgggcg atgtagaatt aattcgtgag gcagaagatc tcagcgatct
    12601 agaacgacgg gaacatttgc catcccggtt ggatctgaga aaatttgcac ccacaagctt
    12661 atgaaaatct cggcattaca gacgctccga catctggtat atgccgtatg cgctgctact
    12721 gctgaaatcc tgtttttacg tggagtcggt gttggagcct tgctgctgtc cgccatgttg
    12781 ctgcaaccct cggtactggt gatgggtcta acaggggtgc ttgcagcagt tggctttgct
    12841 aaagtagcgc aactggatgt agcatattgg aagcaaggac cctttttatt caatccgctt
    12901 ctagcggggc taggtgttgg ttatttattt caactaagtg cggcatcact gtttctggct
    12961 gctgctgccg gtatactagc atttacctta acttggactt tgtcctacgt acttcacaca
    13021 ttttttttgc taccagtact gagtttgcca tttgttaccg taagctggac tattcattta
    13081 gcagcattcc gctttgctgg tttgcagcac gctattgtgc ctgcacatgc ttactccatt
    13141 ggcttaccag tgccgcttga aggtttcttg cgtacattag gcttgatctt cttcttgccc
    13201 aatgtatggg ttggcatgat agttgcactc ctattattgt ggaattcacg catacagttt
    13261 ttgttagctg tattcagtta tacttttgga acttttatcc aaggtatcct gacaggaacg
    13321 ttcgcttatg tctactacga ccctgcaaca ttgaatttca tcttggtagc actggcgctt
    13381 ggcggatttt acttgctgcc atcacctcaa agctacatac tagcagcgct tggcgttgca
    13441 ttggcagcct tgctgggtca agctgtgagt gtcttctggg cagcagtggc gttaccagta
    13501 catgcattgc cgtataatgt agtcaccttg atgctattgt atctgctggg tcttgtaggg
    13561 catcatttgt tagcaagata ccctcaatcc tcaccagaaa aaaccttgga ttatgaattg
    13621 acagcaagac agcggtatca cgggagtaca ggtcgcctcc tggccttacc ttttacagga
    13681 aattgggtag tttggcaaag ctttgacgga caatggactc atcaggggct ttggcgttac
    13741 gcttatgact ttctcatccg cgacgaggga ggtcttactt acagcgacga cgggttaaaa
    13801 ttaacagatt attatgcttt tcaaaaaccc gtgctgtcac ctattcgtgg ttcagtggtt
    13861 ttggttgtgc gggatctacc agactgcgag atcggtcatg tagaccaaga ccgtaactgg
    13921 ggtaactacg tgttactgta cgatgaacgg ggcttttacg tcgaaatatc ccattttgcc
    13981 cagaacagta ttgcggtcaa tcagggcgat cgcattgagc gaggagcctt actcggacgt
    14041 tgcggtaatt ctgggtactc acctcaaccc cacatccaca ttcaggtgca actgactccg
    14101 gtcatcggag cagcgactgt tccgttcaat tttgccaact tcatggtgaa cggtgaattt
    14161 tgttccgagg gtataccagc aaaagatgct gtggtagagc ctgtgactcc ggatcgctct
    14221 ctcacacaag cacttacctt cgcccttgat tcccagttac actttagtct cactcgaaag
    14281 ggacgagaga tcggtcaatt gagggtaaca aaccggatgg caattgatgg ttcattttac
    14341 ctggattctg gaaatgccaa attgttttat acccgagatg agaacaggtt gatgttccat
    14401 cgattagacg gaaaagatcc aagacttgcg ttgctatttc ttgcaatgcc cagactgcct
    14461 ttaatacgtc agatcgatcg gcaatggttt gactacttac caattagtat ggtggtaaca
    14521 gggctgcgtc tgatgcttta ccagttttgc agttctttgt atcccaagct agcttcagca
    14581 cactatatcg ggcaatggca atctgatggc atattaattg gcacgatttc aataccaaaa
    14641 gtcgcacgca aaattcaaac ctctgccatc ttcaatcgcg acaaccagtt agtcaaagtt
    14701 actgtgggcg atcgctctct tgtacgtcag caataaaaga tagcgtggtt caattagata
    14761 agctgtcgcg catctaaatt gtactttttt aagcttgaaa acattgctgt gaggttgtta
    14821 gctttaaaat ttcagacgtc ttagcttaac agggagttga ttccaatttc cccccttaaa
    14881 aaggggggtt aggggggatc gaaagcgcaa gaacgcactt tagaagactt gtgtacacta
    14941 ccgtagccaa aacccgatcg ctctagaggc taagagggaa ttgagtctta tctgaactgt
    15001 attgacctat gagaatttat ggagtcaatt gttagtacag cacggctaaa ataaagcaac
    15061 tatttagtaa caggcaaaaa gccttctgtc atcagacgag cgttcggggc taccttcatg
    15121 tactagtgca ttttgtaatc ctagatgaaa aaacattatg cctaaaaaag ttgtgaatta
    15181 tctgattttg catttaacaa gtctagttag tggattatta cttacaaatg caactttagt
    15241 gacagaaaca caagcagttt tcaacgagca gttagagatt gcaccaatgg ctcgagtcaa
    15301 ttcagtttcc caacttcttg atataggagc aaaggattgg gaatttcaag cagcacagtc
    15361 tttatttgaa cgttatggtt gcactgaagg ctattttgac aaaacataca gaggaaatca
    15421 gactctaacc cgttatgaat ttgcttctaa attaaatgta tgtatagaac aaattaacaa
    15481 attgctgact cagagtactg ttaatttgag ccaggaagaa gatttagaaa catggaaaaa
    15541 actgcaagag atatttgcag cagaacttgc tactttacaa agtcgagtcg ctcggcttga
    15601 gatgcagacc accactttgc aggaacaaca attttctgct acaaccaaac tcgttggcga
    15661 agttatcttt gcgcttacag atgaattcaa tcagccgact aacaataata ccgtttttca
    15721 agaaagagcc cgcttaaact ttcagagcag cttcacggga aaagatagac tgcatatcag
    15781 aattgcatct ggtaacgcga atatctttaa tttgacaggt tatggagttg aagcaattca
    15841 gacctttaac ttcggaaata ctaacaatac aatctctgct gactggatat cctacttttt
    15901 cccaattggt aagaacattc aaggttatgt tgctgctgtt ggaggtgttc attatgacta
    15961 tgctcccaca gtcagttctt acgtagaagg atacggtagt ggtaaaggtt ctctgtcggt
    16021 ctttggtcaa cgcaatccta tttatttaat tgggggtggt tctggaggtg gagtcactta
    16081 ctcattcagt caaaatttat tattatctac aggttattta gcagatagtt ataatttatt
    16141 tgatggcaat tacgcagcct cggctcaact cactttttcg ccaagtaacc agttttcaat
    16201 tggtctgact tatattaatg catatcgaca atttgctatt tttgatacgg ggagtaacct
    16261 tgcttcagtt ggtactaact tagcaaacgg tggaggtttt gatgttggta cagttccatc
    16321 aaaagtcaat gcttatggtg cagaatttac gtacagattt aaccctcgat ttacaattaa
    16381 tggctggttt tcctatataa acgctcattt catgaatctt ggaactggag atatttggac
    16441 ttatgcactc acctttgcct ttcccgatct tggtaaaaaa agtaacttag gtgggattgt
    16501 tgtgggtgta gagccttatt tggggaatgc gagtcagttt gctgtcaatg ctaagaatga
    16561 tgtcccaatt catattgagg gcttttacca acatcagata aatagtaaca tctctgtgac
    16621 tcccggtttg atttggattc tttcaccagg acaaaactct gaaaatcgtg actcaattat
    16681 ctgtactctt agaacaacct ttgcgtttta atgaaatggg ataaaaatta tctatttcta
    16741 caacaactat gaatggctca gaggacctga agaggtattt ggacgaacaa ggacgggtaa
    16801 aagaatggcc ttccaagcga aatagaagta ggtttcagca attggtttta gagtatttgg
    16861 caaatcaatt tgagattgac agcatttatt cagaaaaaca agttaaccaa ttgctgaacc
    16921 agcatcatac ctttggcgat ccggctttgt taaggcggga gttatttgag cgaggattgc
    16981 tcgatagaaa gcgagatggt tcggcatact ggcgtaaaat tcagaattga cgggaccagt
    17041 tgctaggcca gcgttctaca acaacttttg tttgggtaaa aaattcgaca gcgtggttgc
    17101 tttgaccgtg taagtcacca aaaaagcttt ctttccaacc gctaaatggg aagaatgcca
    17161 ttggtgctgc aactcctata ttgatgccaa tattaccagc ctcggcttca taacgaaatt
    17221 tacgtgcagc agcaccgctt gatgtaaata aacaagccat gttcccatat tgaccgccgt
    17281 tgactagggc gatcgcttgc tcaattgtct ctacatgaat taggctcagt acgggaccaa
    17341 atatttctgt acgggcaatg tcaccagatg gatcgacatt ttgtagaatt gtgggacgta
    17401 caaagtaacc cctttcataa cttggtatat tgggagaccg tccatctacc agtactgttg
    17461 ctccttcatc tgctccctgc tgaattaaac cctcaattct tgccttgctt tgagcagtaa
    17521 tgacgggtcc catttctata ccggggtcta aaccagaacc aacagcacgc ttttgagcag
    17581 tttctgcgat cgcttcggtg aaactccgac gtgcttctcc aacagtcaca gcaatggaag
    17641 ctgcaagaca gcgctgtcct gcacaaccaa aggcactatc agcagcaatg cgtgttgtca
    17701 tctccaaatc tgcatctggc aaaacaatca gtggattttt agcaccacct tggcattgaa
    17761 ctcgcttgcc gttagtggct cctctactat atatatactt agcaactggt gtagaaccta
    17821 caaagctaat cgctcgaatc ttgggatgat ctaaaattgc gtccacaact tctttggcac
    17881 cattgactaa gttaacaaca ccttgaggca atcctgtttt ttccaataat tgaaaaactt
    17941 tttgcattgt cagaggaact ttttctgatg gcttaacgat gtaagtattt ccacaagcaa
    18001 tggcataggg taagaaccaa aaggggatca ttccaggaaa attgaacgga gcaatgacag
    18061 cgcacacgcc taaaggttgt cggatcatca tttcatcaat acccctagca atgtcttcca
    18121 agttggttcc ttgcatcatc atggggattc cacaagcaac ttcaacattt tcaatagcgc
    18181 ggcgcatttc acctttagac tcagccaaag ttttaccgca ctctaaggta atggtacgag
    18241 ccaagtcttc aaagtgttct tctagtaaat tcttgagttt aaagagatac tgtactcgtt
    18301 ctgttggtgg tgtacgccgc caatttccaa aagcctctga ggctgcttgg actgcttgct
    18361 ctacctcaga agctagagag agtgggactc gagccaatac ctctgctgta gctggattaa
    18421 ttacgtccaa atactctgta gcgttagaag tacaccactg attgttaatg taattgggta
    18481 gtgcgatcgc tttttccatc agttaaatat tatgttgcta tgagtgcagg attatgaata
    18541 tcctactggc aaagcattac agtcaacaat ctagttttga aacccgtatt ttgttttagg
    18601 tggatgggta ttgagcaaaa ttggggttta cattaaaaaa tgttaaaatt aatactttaa
    18661 ttatagattt tctactggta tgttggctaa ataaatctcg aatataatat atatagtaag
    18721 tttgtcagac ccccgtagag tagtgatttt tttacacccc acaaccttct aatgatgttc
    18781 ataatgagtg ttgtgctacc ttggtattac ttgtcaagca aattgttcaa caattgagag
    18841 gaaaacgtta tcgtaattca aaagcaactc atcaactcac aaatcaagtc acctcaagtc
    18901 ttcttgattg accacgagaa taacaatcgt ggtttgactg atacccgtga agctctacaa
    18961 ctagctgaga gcgtagatct tgacttggtt gtagtctccg agagcaaaga tgctccagtg
    19021 gcgaagatcc tgaactatgg caagcttcag tatcaaaaga aaaaacgtca aacacagagt
    19081 gccagaccca cggttaagga agttcgtctt cgtccaaaca taggtctagc tgattacaat
    19141 ttacgcatca gtcaagccag tcagtggttg agtaaaggcg attcagtaaa atttatgatt
    19201 cgcttaagag gtcgagaaaa tcaatatcgc agtaacgccg gagaattgct agaccgcatt
    19261 gtagcggatc tgagttcagt gggtaaagtc cagtcacttg ataaacggtc actgattgtt
    19321 caagtcattc ccgcataatt taatttttta gggatttctt taagatccct tcatcaatgg
    19381 gcgctaaatg agcgatttga gtcacgagct caaatcgctt atctgtaatt tgaggataaa
    19441 aaagaaacag gtgcgaaatc tagtaacctc gcacctccca aagaaaaaat ttttccaaaa
    19501 gggaatcctt tgtatttaaa aatagggcaa aaaaatggag actttgtgaa gccttgaaat
    19561 gcaagcttca tcaggaattt taagtactgt agtgaatata aaaaatcacc ctatttggtg
    19621 aaccaagtag gcgatgctga aaaaatataa attccatata cttagtgtat caatctcaaa
    19681 ggcaaaaaca agtttaagct agcaaccaat gcaagaaaaa taacaggagg taaaaatggt
    19741 aaaaacccaa ccttgtaatt gtgctaactg tggtaagcgt gtatttgctt ggatgatgtc
    19801 tttagataga gggggtccat atgatgaagc tgtacgcgat cgcaagcaat ccttatttgg
    19861 tagtctcaat ggtaatgttt tagaaatcgg tcctggaact ggcgttaacc tagcttactt
    19921 tcccaaaaac atcaattgga taggaattga gccgaaccca tttatgcatt cctatctcaa
    19981 aatagaagct caaaaactca atttcaacaa tattgagatc cgtactgcta gttctgagcg
    20041 tatagatgca gaagacaata gtatggatgc tgttgtaagt accctcgttc tatgttccgt
    20101 tcccaattta tataatacgt tacaggaaat tttacgagtg ctgaaaccgg gcggacattt
    20161 tctatttatt gaacacgttg ctgcacccca ggaaacaatg ttgagaaaga ttcaaagtac
    20221 gattcgtcct gtatggaaat taataggaga tg
//
