LOCUS       NZ_JHEG04000001        20927 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Tolypothrix bouteillei VB521301 NODE_1_length_9494340_cov_10.278967,
            whole genome shotgun sequence.
ACCESSION   NZ_JHEG04000001
VERSION     NZ_JHEG04000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Tolypothrix bouteillei VB521301
  ORGANISM  Tolypothrix bouteillei VB521301
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Tolypothrichaceae; Tolypothrix.
REFERENCE   1  (bases 1 to 9494340)
  AUTHORS   Chandrababunaidu,M.M., Singh,D., Sen,D., Bhan,S., Das,S., Gupta,A.,
            Adhikary,S.P. and Tripathy,S.
  TITLE     Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
  JOURNAL   Genome Announc 3 (1), e00001-15 (2015)
   PUBMED   25700407
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Improved Assembly of Tolypothrix boutellei genome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9494340)
  AUTHORS   Sarangi,A.N., Mukherjee,M., Ghosh,S., Singh,D., Das,A., Kant,S.,
            Prusty,A. and Tripathy,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S. C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
REFERENCE   4  (bases 1 to 9494340)
  AUTHORS   Tripathy,S., Sanghi,N., Chandrababunaidu,M., Singh,D., Panda,A.,
            Gupta,A., Das,S. and Adhikary,S.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2014) Computational Genomics Lab, Indian Institute
            Of Chemical Biology, 4, Raja, S.C. Mullick Road, Jadavpur, Kolkata,
            West Bengal 700032, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: SPAdes v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000760695.4-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 03:45:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,181
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,922
            CDSs (with protein)               :: 7,922
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 41 of 164
            Pseudo Genes (incomplete)         :: 132 of 164
            Pseudo Genes (internal stop)      :: 36 of 164
            Pseudo Genes (multiple problems)  :: 40 of 164
            CRISPR Arrays                     :: 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 448267
            Orig. end                         :: 469194
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JHEG04000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20927
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20927
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20927
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10927](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10927
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(1603..2391)
                     /locus_tag="HC643_RS01775"
                     /old_locus_tag="DA73_0400001775"
     CDS             complement(1603..2391)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (31-156). E-value:
                     6.4e-23. Score: 73.6. Matches aSDomain:
                     nrpspksdomains_HC643_RS01775_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016860489.1"
                     /locus_tag="HC643_RS01775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001775"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_237265811.1"
                     /sec_met_domain="PF00561 (E-value: 1.5e-17, bitscore: 62.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-13, bitscore:
                     50.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKSQLTNHRVDLQDCTIFYQQSKLESSSIPILFLHGWGISTEP
                     YTEVLTLIALQHTIIAPDLPSFARSTHSELIPDYASYSKFLLSFLEALNLQQFHIVGHS
                     LGGGIAITLSTLVPEKVRSVILVDSTGIPSPSIPEMIPRRAIEMTVQMFLPRPRLKLVD
                     IPLVFSYNLLFNTGNVIQGLLISIYEDISHLLPKIQAPCLLLWSDKDLTTPLNNAQEMA
                     AIIPNSKLITVEEGLHEWGLWYPEKLTSLILDFIAQLEQY"
     aSDomain        complement(1924..2298)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HC643_RS01775_Abhydrolase_1.1"
                     /evalue="6.40E-23"
                     /label="HC643_RS01775_Abhydrolase_1.1"
                     /locus_tag="HC643_RS01775"
                     /protein_end="156"
                     /protein_start="31"
                     /score="73.6"
                     /tool="antismash"
                     /translation="PILFLHGWGISTEPYTEVLTLIALQHTIIAPDLPSFARSTHSELI
                     PDYASYSKFLLSFLEALNLQQFHIVGHSLGGGIAITLSTLVPEKVRSVILVDSTGIPSP
                     SIPEMIPRRAIEMTVQMFLPR"
     CDS_motif       complement(2059..2100)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HC643_RS01775_0001"
                     /evalue="2.30E-04"
                     /label="NRPS-te1"
                     /locus_tag="HC643_RS01775"
                     /protein_end="111"
                     /protein_start="97"
                     /score="13.7"
                     /tool="antismash"
                     /translation="FHIVGHSLGGGIAI"
     gene            complement(2680..3228)
                     /locus_tag="HC643_RS01780"
                     /old_locus_tag="DA73_0400001780"
     CDS             complement(2680..3228)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013989.4"
                     /locus_tag="HC643_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001780"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_038090750.1"
                     /transl_table=11
                     /translation="MRKLVYHVGTTLDSYIAHEDGSIDGFLKFAEGEHVTEYFESLKTY
                     DTAVMGKRTYEFGYQYGNKPGEPAYPHMKNYIFSKTLKFDTELDDRVKIIAQNELEAIE
                     QLKEADGTDIYLCGGGTFAGFLLDNELIDELIIKLYPIILGRGIKLFGKSKKAIHLSLI
                     NSKSYNTGVLLLTYKLNYN"
     misc_feature    3316..3329
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.98"
                     /tool="antismash"
     gene            complement(3352..5946)
                     /gene="mutS"
                     /locus_tag="HC643_RS01785"
                     /old_locus_tag="DA73_0400001785"
     CDS             complement(3352..5946)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0030983 - mismatched DNA binding [Evidence
                     IEA]"
                     /GO_process="GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /gene="mutS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011319919.1"
                     /locus_tag="HC643_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001785"
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="WP_050045134.1"
                     /transl_table=11
                     /translation="MTASHTPQTTEPSNPNEPIGDYRTVDRSKLSKMYQHYVEVKEKYP
                     HALLLYRVGDFFETFFQDAIVVSRELELVLTSKHGGEVGRVRMTGVPHHAWERYTTQLV
                     EKGYAVVICDQVEDASEAVGLVRREVTRILTPGTLLEEGMLKSSRNNYLAAVVIAGDYW
                     GLAYADISTGEFLTTQGSNPEHLTQELMRLQPAEVLVPTNAPDLGSLLRPGERSEHLPE
                     CLPPSFCYSLRSQVPFSQGEARTRLLQKFKVRSLEGLGCEHLALAVRAAGGLLEYLEDT
                     QKENAIPLQTLRTYTLTDFLIIDHQTRRNLEITQTVRDGTFIGSLLWALDKTSTPMGSR
                     ALRRWLLQPLLDIKGIRARQDTIQELVDNNSLRQDLRQLLRQIYDIERLTGRAGSGTAN
                     ARDLLALADSLSRLPQIANLVSVARSPFLKALQKVPPGMEELAQKIRLHIVESPPLHIK
                     EGGLIRSGVDAQLDERRATVEDDQKWIANLEVDERARTGIANLKVGFNKTFGYYIGISR
                     AKADQVPSNYIRKQTLVNEERYITPELKEREARILTARDDLNQLEYEIFVALREEVGTQ
                     AEVIRNISRAIAAADVLCGLAELAIYQDYCRPSVVEGREITIIDGRHPVVEQSLPSGFF
                     VPNSTHLGNGDQGNSPPLPLPPSPSPDLVILTGPNASGKSCYLRQVGLIQLMAQIGSFV
                     PAREAQLGVCDRIFTRVGAVDDLATGQSTFMVEMNETANILNHATSKSLVLLDEIGRGT
                     ATFDGLSIAWAVAEYLATEIRSRTIFATHYHELNELASLLSNVANYQVTVKELPDQIIF
                     LHQVQPGGADKSYGIEAGRLAGLPKVVIQRARQVMGQIEKHSKIALGLQNLE"
     misc_feature    6017..6034
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.78"
                     /tool="antismash"
     gene            complement(6065..6310)
                     /locus_tag="HC643_RS01790"
                     /old_locus_tag="DA73_0400001790"
     CDS             complement(6065..6310)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747454.1"
                     /locus_tag="HC643_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001790"
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_038090840.1"
                     /transl_table=11
                     /translation="MLASYIDQAMELAVYEIIEDDGTYWGEIPILQGVWSNHHTLEGCR
                     RELREALSDWLALRLRLGLMIPVIVGIDLNKLTEPV"
     gene            complement(6504..7622)
                     /locus_tag="HC643_RS01795"
                     /old_locus_tag="DA73_0400001795"
     CDS             complement(6504..7622)
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017741697.1"
                     /locus_tag="HC643_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001795"
                     /product="AI-2E family transporter"
                     /protein_id="WP_038090754.1"
                     /transl_table=11
                     /translation="MTPNKLPQWLSLGLAFPLAILNAWVLLQVVQYFQPLVSILVAALL
                     LAFVLDYPIRFFQKRGINRNFAIVSVLLLAVVIVGALAVTLVPLILEQLNELVNFLPNW
                     IDSGAQQIQAFQAWLATQTVTQDLPVNLSSLVTQLLDRFSNQLQSLTGQILGFAVDTIG
                     SLVNVLLTVVITIYLILNGEKLWDGIFQWFPSYISSPIRQLLREDFQNYFIGQATLGAL
                     LALTLILIFLALQVPLALLFGIGIGFFSLFPFGTGIGIAIVTLLIGLQNFWLGVEVLAV
                     AVLVDQINTNFVAPRILGNLTGLNPVWVVISLLVGAKLGGLLGLLVAIPIASFIKDVTD
                     SWRDGGFRVPPSEDASSDGVALGKTENVILER"
     gene            complement(7678..8121)
                     /locus_tag="HC643_RS01800"
                     /old_locus_tag="DA73_0400001800"
     CDS             complement(7678..8121)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017741698.1"
                     /locus_tag="HC643_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001800"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_038090760.1"
                     /transl_table=11
                     /translation="MQVQVAIAILYRENKFLMQLRDNKPNLLYPGHWAFFGGHMEPGET
                     PEEAVQREILEEIGYKLPPNFSKFGCYSDEIALRHVFHAPLLVELDRLVLNEGWDMGLV
                     APEYVQQGSCYSAVAGEVRPIGAVHQRILLDFIESKPMPLANA"
     gene            complement(8218..8625)
                     /locus_tag="HC643_RS01805"
                     /old_locus_tag="DA73_0400001805"
     CDS             complement(8218..8625)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317435.1"
                     /locus_tag="HC643_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001805"
                     /product="hypothetical protein"
                     /protein_id="WP_038090763.1"
                     /transl_table=11
                     /translation="MQKMKNLNILFLYQYALVLSLRLGLTVLLLTGAFGCTNFGRYGWN
                     TIGANITPIQEIKPPKEDDATVYVQGKVEKRVPLLKRLGYQIDDSTGKVWVITNQTGIK
                     EGDKVVFKGKIRYQSIPIAGKEYGEIYLEEE"
     misc_feature    8920..8938
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.18"
                     /tool="antismash"
     gene            8922..9800
                     /gene="folD"
                     /locus_tag="HC643_RS01810"
                     /old_locus_tag="DA73_0400001810"
     CDS             8922..9800
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317434.1"
                     /locus_tag="HC643_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001810"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_038090845.1"
                     /transl_table=11
                     /translation="MDTKTAKLLDGKVKAEKIQQELSAVIKEAQPKIGRPPGLAVLMVG
                     DNPASAAYVRGKERACKKIGIASFGRHFPTETTEAELEEVIAALNSDERVDGILIQLPL
                     PNHLNAQHLLYQIAPDKDADGLHPENLGRLVRGEVGLRSCTPAGIMSLLEEYNIPLQGK
                     QAVVVGRSILVGKPLALMLLEADATVTVAHSRSQDLPAIAKNADLLVAAVGRPEFITAE
                     MVKPGAVVVDVGINRVTDSSGNSRIVGDVRFEEVARVAEFLTPVPGGVGLMTVAMLMQN
                     TVNSYRQNFKN"
     gene            10001..10927
                     /gene="crtE"
                     /locus_tag="HC643_RS01815"
                     /old_locus_tag="DA73_0400001815"
     CDS             10001..10927
                     /EC_number="2.5.1.1"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0033386 - geranylgeranyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="crtE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015199069.1"
                     /locus_tag="HC643_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001815"
                     /product="geranylgeranyl diphosphate synthase CrtE"
                     /protein_id="WP_038090766.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.4e-65, bitscore:
                     218.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAADNIQTTPQEGKFNLLAYLKEKKQLCDEALDKAVLVHYPEKI
                     YEAMRYSLLAGGKRLRPILCLTTNEMLGGTIEMALPTAVAVEMIHTMSLIHDDLPAMDN
                     DDYRRGKLTNHKVYGEDIAILAGDGLLAYAFEYVATQTQNVPAERVLRVVARLGHATGA
                     TGLVGGQVLDLESEGKTDTPLETLNFIHTHKTGALLEACVVCGGILAGATAEQEQRLSR
                     YSQNIGLAFQIIDDILDITATAEQLGKTAGKDLQANKVTYPSLWGIEESRAKAQQLIEE
                     ACTELEPFGAKAQALIAIAHFIITRDR"
     gene            11029..11502
                     /locus_tag="HC643_RS01820"
                     /old_locus_tag="DA73_0400001820"
     CDS             11029..11502
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317432.1"
                     /locus_tag="HC643_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001820"
                     /product="divergent PAP2 family protein"
                     /protein_id="WP_017745413.1"
                     /transl_table=11
                     /translation="MQDISDILENRVLFVALISSLIAQGLKLVIELVKNRKLNVNVLVT
                     TGGMPSAHSALVTALAAGIGQTLGWASSEFAVAVVFAIIVMYDAAGVRQAAGKQARILN
                     QMIDELFHEHPNFNGDRLKELLGHTPVQVIAGSALGITISWLARSTGVLVVNP"
     gene            complement(11569..12216)
                     /locus_tag="HC643_RS01825"
                     /old_locus_tag="DA73_0400001825"
     CDS             complement(11569..12216)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017745412.1"
                     /locus_tag="HC643_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001825"
                     /product="hypothetical protein"
                     /protein_id="WP_038090768.1"
                     /transl_table=11
                     /translation="MYQAIARTLTKSLVSSLLLAFSSLIAGVDSAIAQSQNVPVCQPPG
                     AGEYLLLVISPTSNNQNQLRRALPGELKTTTCRYLKDTVTRIGGFRSIDDANRWARYIS
                     NVVGLSAIITTRPTEATPGQNVTYKPERLGEGYAVLVDYYNRPEVANEVREVVGGNVGF
                     ATYGQRPYLLAVYTNNQKDAYTTLQKLSEQGFSAVLVDSRKVLLLRSAVRLQ"
     gene            complement(12275..12604)
                     /locus_tag="HC643_RS01830"
                     /old_locus_tag="DA73_0400001830"
     CDS             complement(12275..12604)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016875706.1"
                     /locus_tag="HC643_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001830"
                     /product="MgPME-cyclase complex family protein"
                     /protein_id="WP_038090771.1"
                     /transl_table=11
                     /translation="MQKYYYVLASQRFLLEEEPMEEVLKERTRHYHEQEKEIDFWVVKE
                     PAFLEAPQMAQIKAKCPQPAVAIVSTDSQFITWLKLRLEYVITGEFQAPSPAIPDALAS
                     VATVS"
     gene            complement(12642..13304)
                     /locus_tag="HC643_RS01835"
                     /old_locus_tag="DA73_0400001835"
     CDS             complement(12642..13304)
                     /GO_process="GO:0030638 - polyketide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015128911.1"
                     /locus_tag="HC643_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001835"
                     /product="ester cyclase"
                     /protein_id="WP_038090773.1"
                     /sec_met_domain="PF07366 (E-value: 2.6e-07, bitscore: 29.3,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAEQSNNLPLWVQDRDTVIANSGNAEWRSQTPPDYTDSKEGLAK
                     ESKANHFEGSLEAIVQNLVRTFEMEASFKTNPSQWLSVVNEQFRMSSNGGPEYTASDVI
                     NSGTYNLFMPDTEDYKASEETFESSGKLFRTAFPKGFLWEVLEVFSGPPNVTFKWRHWG
                     TFSGSYKDYPSTGETVEIVGMSIARVTDDLKILSVEHYFDNSQFLQKLTVGKKQTTT"
     misc_feature    complement(13338..13351)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.35"
                     /tool="antismash"
     gene            complement(13434..14150)
                     /locus_tag="HC643_RS01840"
                     /old_locus_tag="DA73_0400001840"
     CDS             complement(13434..14150)
                     /EC_number="2.6.99.2"
                     /GO_function="GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317428.1"
                     /locus_tag="HC643_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001840"
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="WP_038090775.1"
                     /transl_table=11
                     /translation="MATLGVNIDHIATIRQARRTVEPDPVAAAVLAELGGADGITVHLR
                     EDRRHIQERDVRLLRQTVRTHLNLEMAATDEMVAIALDIQPDYVTLVPEKREEVTTEGG
                     LDIVGQIDRMEAVVNKLQGAGIPVSLFIDAEPAQIEASVKIQAQFIELHTGRYAEAKNE
                     TSRQQELTFLAKGCEQAIQAGLRVNAGHGLTYWNVFPIATFPGMEELNIGHTIVSRAVL
                     VGMERAVREMKLAMRA"
     gene            14286..14726
                     /locus_tag="HC643_RS01845"
                     /old_locus_tag="DA73_0400001845"
     CDS             14286..14726
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019494101.1"
                     /locus_tag="HC643_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001845"
                     /product="nuclease A inhibitor family protein"
                     /protein_id="WP_237265812.1"
                     /transl_table=11
                     /translation="MNYKLSNSEQPSNSSLSLINILKQASDGLLFISESESPFEVFLWD
                     DSEQKDITPELVLQKIGLPLETPVEMVELDSFFEVAIAEQNWHSAEDKITVNKYQNLVK
                     VLKENLSDIKVMRFGTISIDVYIIGKTLNNRLAGLSVKVVET"
     gene            complement(14727..15572)
                     /locus_tag="HC643_RS01850"
                     /old_locus_tag="DA73_0400001850"
     CDS             complement(14727..15572)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017745406.1"
                     /locus_tag="HC643_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001850"
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="WP_038090777.1"
                     /transl_table=11
                     /translation="MFASKKLLILLITLLLTLVVGCTILFPRPLATNPRLPFGNPSNAS
                     QTDPNNYLIEKPQYVLSYNRDKGIPNWVSWELNQSWLGEAPRSNNFRPDDTLPEGWYRV
                     TPNDYTKSGFDKGHMVPSADRSNNPENNAATFLMTNIVPQAPDNNQGYWARLEDYERSL
                     ANQGNQLYIIAGVYGQKGTIAQGKVSIPDRIFKIIIAIAPNDSVNRINESTRIIAVDTP
                     NTNGNRDAAWTEFLTSIDAIEYQTGYDFLSEVNPSIQNILESKKYQISDLKLKSKTRKK
                     "
     misc_feature    complement(15539..15553)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.6"
                     /tool="antismash"
     gene            16250..16927
                     /locus_tag="HC643_RS01855"
                     /old_locus_tag="DA73_0400001855"
     CDS             16250..16927
                     /GO_component="GO:0031240 - external side of cell outer
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02595.1"
                     /locus_tag="HC643_RS01855"
                     /note="PEP-CTERM proteins occur, often in large numbers, in
                     the proteomes of bacteria that also encode an exosortase, a
                     predicted intramembrane cysteine proteinase. The presence
                     of a PEP-CTERM domain at a protein's C-terminus predicts
                     cleavage within the sorting domain, followed by covalent
                     anchoring to some some component of the (usually
                     Gram-negative) cell surface. Many PEP-CTERM proteins
                     exhibit an unusual sequence composition that includes large
                     numbers of potential glycosylation sites. Expression of one
                     such protein has been shown restore the ability of a
                     bacterium to form floc, a type of biofilm; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="DA73_0400001855"
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="WP_050045135.1"
                     /transl_table=11
                     /translation="MVNLSLIRSTLIANAVSIISLASLLLVPSQAAVINGNFDNDLKNW
                     EAKGSVNLIDGQALMSAYGDDVTVVETFLELSDGTLNAVNRTSAANGSAIKQTITVNAG
                     DILSFNWKFQGGDYLPFNDFSFYSINSIAYKLADIAQVGSFEESSSQTFHTFQTAGTYT
                     IGFGVLNALDTSGTSFLAIDNVKVSSTTTVPEPASIIGILTISAISGTSALKRKQLVKA
                     RQN"
     misc_feature    16952..16965
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    complement(17333..17349)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.48"
                     /tool="antismash"
     gene            17456..18760
                     /locus_tag="HC643_RS01860"
                     /old_locus_tag="DA73_0400001860"
     CDS             17456..18760
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408160.1"
                     /locus_tag="HC643_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001860"
                     /product="GAF domain-containing sensor histidine kinase"
                     /protein_id="WP_050045136.1"
                     /transl_table=11
                     /translation="MIKAIEKKTLQNQMWQRSRQAIALLSSLNYRTGELSSYLHNVACG
                     VSELLNVDWSVVTFCQEGFEKVLASSIDIGEGEHLYSLHGSLTGTVVKTGCSLVVKDAK
                     EHPEFGEAPEGYNAYLGIPLRTAEGEVIGTICSFHQQPREFSEEEIQLGELFAERAATA
                     IDNYHLYKQQCQFNQILEAEVQKRTEELRTAQAKLVEQERLAAIGEFAAMIVHEIRNPL
                     TTTILGLKYFQKTVLTESAKERLSLSLNEASRLDNLLSEILLYAKPQVLQLCELDVDRF
                     MSELLNDMSEMQEAVARKIELIPVSVPVKILGDKDKLKQVFINIVRNACEAVSPGDAIK
                     WEVDISDPEQVCINVCNKGQPIPPEVLSKLTQPFFSTKPSGTGLGLAITKRIVNAHGGE
                     LFIHSDTTGTTVSVQLPRIHLLDFGQKNHNLSVFI"
     gene            complement(18920..19537)
                     /locus_tag="HC643_RS01865"
                     /old_locus_tag="DA73_0400001865"
     CDS             complement(18920..19537)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017740848.1"
                     /locus_tag="HC643_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001865"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_038090780.1"
                     /transl_table=11
                     /translation="MNSSNLLEQELIRWNNVISSHPHDPKAYIYRGMVHFKLGNIHESI
                     ADFDTAEKLDPRLTPYLWQRGLSYYYAERFAEGAKQFEIDLTINSHDVEETVWRYLCIA
                     RLHGPTQARQSLLEVRNDSRFVMRRVYDFYAGHCSVDDVLAVGASNDRRQSFYSYLYLS
                     LYFEVESQLEQARQYMTQAVSYKIDDYMWHLATVHQKLRRWD"
     gene            complement(19586..20749)
                     /locus_tag="HC643_RS01870"
                     /old_locus_tag="DA73_0400001870"
     CDS             complement(19586..20749)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015120438.1"
                     /locus_tag="HC643_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DA73_0400001870"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_038090783.1"
                     /transl_table=11
                     /translation="MSLNCCLISGPVLSPSLLRAVQKYAIPVYVQPPTPPLPETIPTLE
                     DTEAKSLVANRDTAVIMNWEASLCFILQNLSHTQLSQVNVFKDKAAFRELLKESHPDLF
                     YVELTRETLQDFQLPQEIKAVVLKPSLGTASIGIRTVRGQQEWARTVDSVLQDIDRATK
                     SMNSAMLSSSRFLVEEFVEGEEFACDGFWDANGRTVITGVYHHPFASESDVSDTLYYTS
                     RQVVAQTLEPLTRLMDKIGTKLDLHRFPFHFEFRRYSDGSLFPIELNPLRFGQVALPDL
                     TEYTFNFNPYELFFTDRSPDWDSLLAEEDSSNIYAFVLGSLPPHYETGKYSIDEESFRK
                     TFGNKLLNYIPSNPAITPFFGVAHIVAERLEDVLSYLHLDFDSFLCK"
ORIGIN
        1 caaccaacaa ttacgggaac tgccacagtt aataatgcaa cttttcaagc acaagttctg
       61 caagatccat taactaatgt gacgggaaca cttgcattta atggcaatag ggtagatgtc
      121 caagggattc aaggacagta caatcgagga aatttgactg ctgaggggat tattcccatt
      181 tttgccagcc aacaagctca acaggaagca gcaacaaacc ccctcaaagt atctctgcaa
      241 aatctgaatt tgaccgttca gaatctgtat caaggtggtg tcagtggtaa tgctgtcatt
      301 gggggaagtg ttttaaaacc cgatatcagt ggtgagattt tattaagtga tggtcaagtc
      361 accatcggac aacaagcagc gggtaacgct tcacaaggtg gtcggacaaa aagtaatgaa
      421 gtctcagccg ccgaaacagc acaaaataca ggtggttctc ccggtcgtgc tgcacccgca
      481 ctgaccgatt ctcctatcga atttaccaac ttaaagctcg ttttgggcaa taatgttcgt
      541 gtcaccacgc aatcagtatt tggtaatttc ataccatcgg gagtcgatcc aacgcaagcc
      601 atactgagct ttgttgcgaa gggagatctg aatattaatg ggactttagc aaaacccgta
      661 cctgaaggaa ccattcgact tacaggtggg caagttaatt tatttacaac tcagtttacc
      721 ttagagcgag gttacgaaca cacagcagag tttattccaa gtcgggggct tgacccgatt
      781 ttagatgtcc gaatgattgc tcttgtaccg gaaactagtg gaagtaggat tttgacttct
      841 cctgtcattt cttcggagat cagtgacatt ccttcaacaa gtattgggac tttaagaacg
      901 gtacgcgttc aagcgagagt agacggaccc gccagtcaat tagctgataa tttggaatta
      961 acaagcgaac cccgtcgcag cgaaccagaa attattgcgt tattaggtgg atcgattatt
     1021 aatacattgg gtcaatcaga tacagcattg ggaattgcta cttttgccag ttctacggtg
     1081 ctggggggac tgcaaggaag tattagtgca ttaggacaag cgatcggatt tagtgaattt
     1141 cgtatatttc ctacaaatgt tgctaacgaa gcgtcaaggg cttctgtatt gggtttagct
     1201 gcagaaggtg tttttgatat taataggcgt ttctctgttt cgctctctag agttttctta
     1261 actaatgagc ctttccgtta caatgtgctt taccgggtga atgacaatac tctcgtgcga
     1321 ggttccacag atttggaaga tgaaagtcga ttggaatttc agtatgaaac gcggttttag
     1381 ttttttaggg ggatcgaaac cgcaagaatg cactttagaa gaaaaaacac gtttgcgatt
     1441 gaaatcgccg ctatacaggc taagcccacc tacgtgggct taataagaag tccttgtctt
     1501 gcggacttcg tttgtatagc cgtgatttct aattactaag ctaaaagggg ttagaaaagc
     1561 ggatttggta taagtcatta accagtcata gaggtgaccg tatcaatatt gctcgagctg
     1621 agcaataaaa tccagtatga gtgatgtcaa tttctcagga taccagagtc cccattcgtg
     1681 caaaccttct tctacagtaa ttaatttaga gttgggaata attgctgcca tttcttgagc
     1741 attatttaat ggcgtagtta ggtctttatc agaccataat aacaagcatg gagcttgaat
     1801 tttcggtagc agatggctga tatcttcgta tatagaaatt agcagtcctt gaatgacatt
     1861 tcccgtattg aataacaagt tataggagaa caccaaaggg atatcaacta atttcaatct
     1921 gggtcttgga agaaacattt gaaccgtcat ttcgatcgcc cttcgcggta tcatctccgg
     1981 tatagatggt gagggaattc cagtactatc taccagaatg acacttctga ctttttctgg
     2041 aacaagtgta gataaagtaa tggcaatacc tccacctaat gagtgtccta ctatatgaaa
     2101 ttgttgtaaa ttcaaagctt ccagaaatga caggagaaat ttgctgtagc ttgcgtaatc
     2161 gggaattagc tcagagtgag tcgatcgcgc aaaactgggc aagtcaggag caattatggt
     2221 atgctgaagt gctatcaatg tcagcacttc agtataaggc tccgtagaaa ttccccatcc
     2281 atgtagaaat aggatgggga ttgaactcga ctccaactta ctttgctgat aaaatatagt
     2341 gcaatcttgt aaatcaactc gatgattcgt taattgggat ttcaaagcca caacctcatt
     2401 cactatgact cgataaatca cttcagcgat aatattacag tagcaagctt agagggtggg
     2461 cgaacctttc tcaaggctta tatcagtcca gatttctgag ttcataaaaa tacagcattt
     2521 tgaggtatgt gaggtacaac aattgcagag ttgcttttaa acgtcggaat ttgaatgaag
     2581 tacttacctc ataaactctg aatttgctgt aataccaatt ctatagggag catcccaatt
     2641 cgagcgttga agaatttcat gcaaaggcgc aaagcttttt tagttataat ttaacttata
     2701 agttaataac aatacgcctg tgttgtagct ttttgagtta attaacgaca aatgaattgc
     2761 ttttttactc ttgccaaaaa gttttatgcc tcgaccaaga ataatgggat aaagtttgat
     2821 gataagttca tcaatgagtt cgttatctaa caaaaaacct gcaaaggttc cacctccgca
     2881 caaataaata tcggttccat cggcttcttt caattgctcg atcgcttcta gttcgttttg
     2941 ggcgataatt ttaactcgat cgtctagttc tgtatcaaat ttcaaagtct ttgagaatat
     3001 gtaatttttc atgtgaggat atgcaggttc tcctggtttg tttccgtatt gataaccaaa
     3061 ctcgtatgtt ctttttccca tgactgctgt atcgtaagtc ttgagacttt caaagtattc
     3121 tgttacgtgt tctccctctg caaactttaa gaagccgtca attgaaccat cttcgtgagc
     3181 gatataacta tcaagggttg tacctacgtg ataaacgagt tttctcattt taatgttctt
     3241 ttttgtgtac cagtcaattg gagcaaacaa tcctttctcg ttcgtagttg cgatgcaggg
     3301 gctaaagctc aactacgaac gtactttctg ctttttaaaa aagggctttc tttattccaa
     3361 attctgcaac cctagtgcaa tcttactgtg cttttcaatc tgtcccatca cttgtcttgc
     3421 tcgttgaata actacttttg gtaaaccagc caatcttccc gcttcaatcc cataagattt
     3481 atcagcacct cccggttgaa cttggtgcaa aaagataatt tgatctggta attctttaac
     3541 tgtgacctga taattagcaa catttgataa caacgaagcc aattcgttca attcatggta
     3601 atgtgttgca aaaattgttc gggagcggat ttctgttgcc aagtactcag cgacagccca
     3661 agcaatagaa agaccatcaa aagtcgctgt tcccctacca atttcatcta acagcaccaa
     3721 tgattttgat gtggcgtggt tgagaatatt tgctgtctcg ttcatctcca ccataaaagt
     3781 agattgacct gttgctaaat catctaccgc accgacacga gtgaaaatgc gatcgcacac
     3841 tcccaattgt gcttctcgtg cgggtacaaa gcttcctatt tgcgccatca gttgaattaa
     3901 tcccacctgt ctgagataac aacttttacc acttgcattt ggtccggtaa ggataaccaa
     3961 atcaggagag ggagaggggg ggagggggag agggggggaa tttccctggt ccccattccc
     4021 caaatgagtg gaattcggta caaagaaacc ggaaggtaaa gactgttcca ccacgggatg
     4081 acgcccatca ataattgtga tttctcgccc ttccaccacg gacggacgac agtaatcctg
     4141 atagattgct agctcggcta acccacacaa aacatctgct gctgctattg cacgggaaat
     4201 attgcgaatc acttccgcct gcgtacctac ctcctctcgc aaggctacaa aaatttcgta
     4261 ttctaactgg tttaaatcat cccgcgctgt tagaattctg gcttcccgtt ccttcaactc
     4321 cggagtgata tagcgttctt cattcaccag ggtttgtttg cggatgtaat tcgatggtac
     4381 ttggtcggct tttgcacggg aaatcccaat atagtaacca aaagttttgt taaatcctac
     4441 ctttaaattg gcaattcccg ttcttgctcg ttcatcaact tctaaattag caatccattt
     4501 ctggtcatct tcaacagtgg cgcgtcgttc atctaattga gcatcaactc cagaacggat
     4561 caatccccct tccttaatat gtaaaggtgg tgactctact atatgaaggc gaattttttg
     4621 tgctagctct tccattcctg gtggtacttt ttgcaaagct ttcaagaagg gagaacgagc
     4681 aacagaaacc aaatttgcta tttgaggcaa acgagatagg gaatcggcta aagctaataa
     4741 atctctagca ttagcagtac cagaaccagc acgtcctgta agccgttcta tatcataaat
     4801 ttgacgcaat aactgtcgca gatcttggcg cagggaattg ttatcaacaa gttcttgaat
     4861 cgtgtcttgt cttgcgcgaa tacctttaat atcaagcaat ggttgcaaca accatcgtcg
     4921 taaagcacga ctacccattg gtgtagaagt tttatctaac gcccaaagca gagaaccaat
     4981 aaaagtgcca tcacgtacag tttgagttat ttccagattg cgccgtgttt gatggtcaat
     5041 aatgagaaaa tccgtgagag tgtaagtccg gagcgtttgt agggggatcg cgttttcctt
     5101 ctgtgtatct tccaaatatt ccagcaaccc acccgccgca cgcacagcca gggctaggtg
     5161 ttcgcaaccc aagccttcca aagaacggac tttaaacttt tgcaacaatc ttgttctggc
     5221 ttcgccttgg gagaaaggaa cttgcgatcg caagctataa caaaaagatg gaggcaaaca
     5281 ttcaggtaaa tgttccgaac gttctcccgg acgcaataaa cttcccaaat ctggggcgtt
     5341 agtgggaacg agcacctcag caggctgcaa gcgcataagt tcctgtgtca aatgttctgg
     5401 attactccct tgagtggtta agaattcacc tgtagaaata tctgcataag ccaaacccca
     5461 atagtcacct gcaatgacca cagccgccaa gtagttattt ctgcttgact taagcattcc
     5521 ttcttccaac aatgtaccgg gagtcagaat gcgcgtcact tcacgacgaa ctaaacctac
     5581 agcttctgaa gcatcttcta cctgatcgca aataacaaca gcatatccct tttctaccaa
     5641 ctgagtcgtg taccgttccc aagcgtgatg gggtacaccc gtcatgcgta ccctaccgac
     5701 ttctcctccg tgtttgctag tcagaaccag ttccagttct ctggatacaa caatggcatc
     5761 ttgaaaaaat gtttcaaaaa aatcccctac ccgatacagc agtagagcgt gaggatactt
     5821 ttccttcact tctacatagt gctggtacat cttgctgagt ttgctgcggt ctaccgtgcg
     5881 gtagtcgccg atgggctcat tcgggttact cggttcggtt gtttggggtg tatgagaagc
     5941 ggtcatgagt gtctaccaat acacaaggct gcctgccaag atccgatgat aacgtgatgt
     6001 tggtgatact cacaaattgt ttacggtttg ttaatcactt cgattagttt cttctagaca
     6061 ttctttatac tggttcagtc agcttgttta agtcaatacc cactattaca ggaatcatca
     6121 atcccaaacg caatcttaat gctagccagt cgctcaaagc ttctctcaat tcccgccgac
     6181 aaccttcaag cgtgtgatga tttgaccaga ctccctgtaa aataggaatt tcaccccagt
     6241 aagttccatc atcttcaata atttcgtaaa ctgcgagttc cattgcttgg tcaatataac
     6301 ttgctaacat tatctgtatt acctcaccta tgtgctccat tctagcttta tgttgttcct
     6361 cagatttcac caattctcta taggcgatcg agatctaagg gaatgacgct tcacttccat
     6421 aagataagag attttctaat cgcaagcagg ggataaatct tttaccttcc atctgaattc
     6481 cccccaatga tttaccatat aaattatcgc tctaaaatca cattttccgt ttttcctaaa
     6541 gccacaccgt cactggaagc atcctcactg ggtggaactc taaaacctcc atcacgccag
     6601 ctatctgtta catctttgat aaaactagct ataggtatag caaccaacaa acctaacagt
     6661 cctccgagtt ttgcacctac caataaggaa attacaaccc aaacagggtt taacccagtc
     6721 aaatttccta gaattcgagg agcaacaaag ttagtattaa tttgatccac aagtacagca
     6781 acagctaaaa cttccactcc caaccaaaaa ttttgcaatc caattaataa ggtcactatt
     6841 gcaatcccta tacccgtacc gaaaggaaag agggagaaaa atccaatacc aataccaaaa
     6901 agtaaagcta ggggtacttg tagcgctaaa aatatcagta tgagtgtcag cgctagcaat
     6961 gcacccaatg ttgcttgacc gatgaaataa ttttggaaat cctcacgtaa taattgccgt
     7021 atcggcgagc taatgtaaga aggaaaccat tgaaaaattc catcccaaag tttttctcca
     7081 ttcagtatta gataaattgt aatgactact gtcagcagta cattcaccaa actgccaatc
     7141 gtgtctacgg caaaaccaag gatttgacct gttaatgact gaagttggtt ggaaaaccta
     7201 tccaacagtt gagtgaccaa actacttaaa ttaactggca gatcttgggt tacggtttgg
     7261 gtagcaagcc aggcttgaaa agcttgaatt tgttgtgctc cagaatcaat ccaattaggc
     7321 aaaaaattta ctagttcgtt gagctgttcc agaattaagg gaaccaaagt aacagctaaa
     7381 gccccaacaa tgactacagc taacagcaaa acactgacaa tggcaaagtt cctatttatg
     7441 cctcgttttt ggaaaaaccg aattggataa tctaaaacaa aagctagcaa gagggcggcg
     7501 acaagaatgc ttactagggg ttggaaatac tgtacaacct gaagcaacac ccaagcgttg
     7561 agtatagcga ggggaaatgc taagcccaga cttaaccatt gtggtagttt gtttggagtc
     7621 attaatgatt tgctaattgc taatggctaa tggctaatgg ctaattggga ctggtaatta
     7681 agcattagcg agtggcatag gtttgctctc tataaaatct aacagaatac gttgatggac
     7741 tgctccaatt ggtctgactt ctcctgcaac tgctgagtag caactccctt gttgaacgta
     7801 ttctggtgct actaaaccca tgtcccaacc ttcatttaga actaaccgat ctaattctac
     7861 taatagcggt gcatggaaaa catgacgcaa cgctatttca tcagaatagc agccgaactt
     7921 ggaaaagttt ggtggtaact tataacctat ttcctctaaa atttctcgct gtactgcttc
     7981 ctctggggtt tcgcccggtt ccatatgtcc gccaaaaaat gcccagtgtc ccggatagag
     8041 aagattgggt ttattatccc gcaactgcat taggaatttg ttttctcggt agagtatcgc
     8101 aattgcaact tgtacttgca taattatttg ttggttgttg gttgttggtt gttggttgtt
     8161 ggttgttggt tgttggttgc tattaaccac taaccactaa ccgctaacaa attatactta
     8221 ctcttcttct aggtaaattt ctccgtactc tttccctgca atgggaatag attggtagcg
     8281 tattttacct ttaaaaacaa ctttatctcc ctcttttata ccagtttgat tggtaattac
     8341 ccatacttta ccggtagagt cgtcaatttg atatcccaac cgctttaata aagggactcg
     8401 tttctcaact tttccctgta cgtagactgt tgcatcatcc tctttcggcg gtttgatttc
     8461 ctgaatgggg gtgatattgg ctcctattgt attccagcca tatcgaccaa aattagtgca
     8521 gccaaacgct cctgtcagaa ggaggactgt caatcccagg cgtaaggata aaactagggc
     8581 gtactgatac aaaaacaata tatttaaatt tttcattttt tgcataatga ttacctgtac
     8641 ttgccaattt tggcatcagg gatcggctag tgacaattta tatcggttaa gtagcgatat
     8701 ttttatcggt taagtagcgc tcgggggcgg gattgacaca ataagcccca gtttccagtc
     8761 ccgagactct aattttatat ttctttacat agttggtttt atctttgcct accgacttac
     8821 aagcaatctg agaagatatt gaatgtggtg tttaaacgcg aatgcgaatt gtgcatgaga
     8881 tggcaatgcc actgcgtagc gttcttcttc tacgaattgt gatggataca aaaacagcca
     8941 aacttcttga tggtaaagtt aaggcagaaa aaattcagca agaactttct gctgtcatta
     9001 aagaagctca acccaaaata ggacgcccgc ccggattggc agtgctgatg gtgggtgata
     9061 atccagcatc agcagcgtat gtacgtggaa aggaacgcgc ctgtaagaag attggtattg
     9121 catcttttgg taggcatttt cctacagaaa cgacagaagc cgaactcgag gaagttattg
     9181 ctgcacttaa ctctgatgag cgagtggatg gtattctcat acaattgcct cttcccaatc
     9241 acttgaatgc ccagcacttg ctatatcaaa ttgctccaga taaagatgct gacggcttgc
     9301 accccgaaaa cttaggacgg ttggtgcggg gtgaggtggg tttacgcagt tgcactcctg
     9361 ctggcattat gagtttactg gaagaataca acattcccct acaaggtaag caagcagtgg
     9421 tggtgggacg cagtattcta gtcggtaaac ctttggcttt gatgctactc gaagcagatg
     9481 ctaccgtgac ggttgctcat tcgcgatcgc aagatttacc cgcgatcgca aagaatgccg
     9541 atcttctagt tgcagcagta gggcgtccgg aattcatcac tgctgagatg gtgaaaccag
     9601 gtgctgttgt ggtagatgtg gggatcaatc gcgtgacaga ctcaagtggt aacagtcgca
     9661 tcgtgggtga tgttcgcttt gaagaagttg ctagagttgc ggaatttctg acaccagttc
     9721 caggcggcgt aggtctcatg actgtagcta tgttgatgca aaacactgtg aatagctaca
     9781 ggcaaaattt caaaaattag tcatttatct tgtgtcagca aaatatacca aattaggatt
     9841 aacaggattg tttgcccttc agtgaagata gctaaaatac aatgcatttc aatccaagag
     9901 ccaaaatcca tttatccaaa attggtatcg gcaccaatga cgaatgacgc tttcccgtaa
     9961 aattgttacg tagacaacgg aatatcaagg ataattaagg atggtagcag cagataacat
    10021 tcagacaact ccacaggaag gtaaatttaa cctgttagct tatctcaaag agaaaaaaca
    10081 gctttgtgat gaagctttgg ataaggctgt actcgtgcat tatccagaaa aaatatatga
    10141 agcaatgcgt tattccctac tagcgggtgg gaagcggttg cgaccaattc tttgtctgac
    10201 taccaatgaa atgcttggtg gtactattga aatggctcta ccgactgccg ttgccgtgga
    10261 gatgatccac acgatgtcgt taattcatga cgatctacct gctatggata acgacgacta
    10321 tcgacgcggt aagctgacca accataaagt ttatggtgaa gatattgcga ttttagctgg
    10381 agacggttta ctcgcctatg cttttgagta tgttgcaacc caaactcaaa atgttcctgc
    10441 agaacgggtg ctaagagtgg ttgctcggtt gggtcacgca actggagcaa ctggattggt
    10501 aggcggtcaa gtgctggatt tggaatcgga gggcaaaaca gatactcctc tggaaacgtt
    10561 aaatttcatt cacactcaca agacgggtgc tcttttggaa gcttgtgtcg tttgtggtgg
    10621 tattttggca ggagcaacag cagaacaaga gcaacgcctg tctcgctact cccaaaatat
    10681 tgggcttgct tttcaaatta ttgatgacat tctagatatc actgcgactg cagagcaatt
    10741 gggtaaaaca gctggcaaag acctacaagc caataaggtt acctatccca gtctttgggg
    10801 aatagaagaa tctcgcgcaa aagctcaaca actgattgaa gaggcttgta ctgaactcga
    10861 accttttgga gcaaaagcgc aagcattaat tgcgatcgcc cattttataa taactcgcga
    10921 tcgctagata atgaaaatga atgatgaaag acggctttac aagtcaccat ttatcattca
    10981 tatttctttt cataattcat catttataat tcataattca taaatagtat gcaggacata
    11041 agcgacattt tagaaaaccg agtgcttttc gtagctctaa tatctagttt gattgctcaa
    11101 gggctaaagc tggttattga gttagtgaaa aatcgcaaac tgaacgtcaa tgttctcgta
    11161 actacaggag gaatgcccag tgctcattcc gctttggtga cagccttagc agcgggtatt
    11221 ggacaaactt taggttgggc ttcttccgaa tttgcagttg ctgtggtttt tgccatcatt
    11281 gtcatgtatg atgcagcagg agtgcgacaa gctgcgggta agcaagctcg cattctcaat
    11341 caaatgattg atgaattatt ccacgaacat ccaaacttta acggcgatcg cctcaaggaa
    11401 ttattgggac acacacccgt tcaagttata gcaggttcag ctttaggtat caccatatca
    11461 tggttggcca ggtctaccgg cgtactcgtt gtcaatcctt aatcacctga taggagacag
    11521 gggagacagg ggagacaagg gagaataatt cataacccta cgacaaattt actgcaagcg
    11581 tacagccgag cgtaacagca aaacttttcg actatctacc agtacagcag aaaagccttg
    11641 ctcgcttagc ttttgcaatg tagtgtatgc atctttttgg ttatttgtgt aaacagctaa
    11701 taagtaaggg cgttgcccgt aggtagcaaa acctacattt cctcctacaa cttcccgtac
    11761 ttcattggca acttccggac gattatagta atcaactagt acagcataac cctctcccaa
    11821 tcgctccggt ttgtaggtga cattttgacc gggcgtagct tctgttggtc gagttgtgat
    11881 gatagcagat agcccaacaa cattgctgat gtacctcgcc cagcgattgg catcgtctat
    11941 gctgcgaaat ccacctatcc gcgtcactgt atctttcaag tacctacacg tcgttgtctt
    12001 gagttctcca ggtaacgcac gacgcaattg attttgatta tttgatgtgg gactaataac
    12061 caataaaagg tattcacctg caccaggtgg ttgacagaca ggtacatttt gtgattgagc
    12121 aatggcggaa tctacgccag caattaagct gctaaatgct agcaataaac tactgactaa
    12181 agattttgtt aacgtccggg caattgcttg atacataatt ttattctttt ttcaaattta
    12241 tagtgtaaag acgcgccatg gcgcgtcttt acatttagga tacggtagca acagatgcta
    12301 aagcatcagg gatcgctggc gacggagctt gaaattcgcc agtgatgacg tactccaatc
    12361 ttagtttcaa ccaggtaata aattgggagt cagtagaaac aattgccact gcaggttggg
    12421 gacactttgc cttgatttgt gccatttgag gtgcttctag aaaagctggt tctttaacca
    12481 cccaaaaatc tatttctttt tcttgttcgt gataatgacg ggttcgttct ttaagaactt
    12541 cctccatggg ttcttcttct agtaaaaatc gttgacttgc caaaacgtaa tagtattttt
    12601 gcatttttcg tctcttcttg cgatcgcact ttatgatgat actaagttgt tgtttgtttc
    12661 ttaccaacag ttaacttttg gagaaactga ctgttatcaa agtagtgttc caccgaaaga
    12721 atttttaaat catcagtgac acgggctatg ctcataccga ctatctccac tgtctcccct
    12781 gttgacggat aatctttgta cgaaccgcta aaagttcccc aatgccgcca tttaaatgtt
    12841 acgttggggg gaccggagaa aacctctaag acttcccaca aaaatccttt aggaaatgcc
    12901 gtgcggaaaa gtttccccga tgattcaaaa gtctcttcag aagctttgta atcttctgta
    12961 tccggcataa atagattata agtccctgag tttatcacat ctgatgctgt gtattctgga
    13021 cctccattgc tactcatgcg gaattgctcg ttaacaacag atagccactg agaggggtta
    13081 gtcttgaaag atgcttccat ctcaaaggtt ctcaccaaat tttgcacaat agcttcgagt
    13141 gaaccttcaa aatggttagc tttactttct tttgccagcc cttctttaga atcagtgtaa
    13201 tctggtggag tttgagaacg ccattcagca ttcccactgt ttgctataac cgtgtctctg
    13261 tcctgtaccc aaagaggaag gttgttagat tgttctgcgc tcatagaagt ttgaatcccg
    13321 atttaacttg agaaatgcaa acaagctttt ggattttcgc attgacaacc cttctatttc
    13381 agttatcagt tatcagtttc cacgggttac cagtcagctc taaccgttca ctgttaagcg
    13441 cgcatggcta gtttcatttc acggactgct ctttccatac ccacgagcac agcgcgactg
    13501 acaatagtat gcccgatgtt cagctcttcc ataccaggaa aagtagcaat ggggaaaaca
    13561 ttccagtaag tcagcccgtg acctgcattc acgcgcaatc ctgcttgtat tgcttgctcg
    13621 catcctttag ctagaaaggt taattcctgt tggcgactgg tttcattttt agcttcagca
    13681 tatctcccgg tatgaagttc aataaactgt gcttgaatct tgacagaagc ttcaatttgt
    13741 gcaggttcag catcgataaa caaactaact ggaataccag caccttgcag tttattgaca
    13801 acggcttcca tgcgatcgat ttgaccaacg atatccagcc ctccttctgt agtgacttcc
    13861 tcccgttttt ctggaactag agtgacataa tcaggttgga tatctagggc aatagcaacc
    13921 atttcatcgg tagctgccat ttccaagtta agatgagttc tgactgtttg acgcagtaag
    13981 cgcacatcgc gttcttgaat gtgtcgcctg tcttcgcgca aatgcacggt aatgccatct
    14041 gcacccccta attctgcaag taccgctgca gctacggggt ctggttccac cgtccgccgc
    14101 gcctgtcgaa tggtggcaat gtggtctatg tttacaccaa gtgtagccaa cctgagtctc
    14161 cctgtttaca atcctcagga cttgatttta ctggaaattg tgaatttatg gcgttatcat
    14221 ttttatcagt cctccaggca cggcagaggt aattaatgag taaagtggaa tagaagacat
    14281 ttagagtgaa ttataaattg agcaactccg aacaaccctc taacagtagt ttaagtttga
    14341 ttaacatttt aaaacaagca tcagatggtt tgttgtttat cagtgagtcc gagtcacctt
    14401 ttgaagtttt tctttgggat gattctgagc aaaaggatat tacgccggag ttggttcttc
    14461 aaaaaatagg gctcccttta gagacacctg ttgaaatggt tgaacttgac tcgttttttg
    14521 aagttgcgat cgcagaacag aactggcata gtgcagaaga caaaataact gtcaataagt
    14581 atcaaaatct tgtgaaagtt ttgaaagaaa accttagcga tatcaaagtc atgcgttttg
    14641 gaactatcag tattgatgtt tatattatag ggaaaacctt gaacaatcgt ttagcagggc
    14701 tgtctgtaaa agtagtagaa acttagttat tttttgcgcg ttttgctctt taattttaaa
    14761 tcacttattt gatacttttt agattctaaa atattttgga tagaagggtt aacctcagat
    14821 aaaaaatcat aacctgtctg gtattcaata gcatcaatac tggttaaaaa ttcagtccaa
    14881 gcagcatcgc gattaccatt tgtgttggga gtatcaacag caataattct tgtagattca
    14941 ttaatcctat ttacactgtc attaggtgcg atcgctatga taattttaaa aattcgatcg
    15001 ggaatagaaa cttttccttg agcaatagtt cctttctgac cgtaaactcc tgctatgata
    15061 tacaactgat tgccttgatt ggctagagat ctctcataat cttccaaacg cgcccagtaa
    15121 ccctgattgt tatcgggtgc ttgaggaaca atatttgtca ttaaaaaagt agcagcatta
    15181 ttttcaggat tattgctgcg atcggcagaa ggtaccatat gtcctttatc aaaaccgctt
    15241 ttcgtgtaat cgttaggggt gacacgatac cagccttccg gaagggtatc gtcaggacga
    15301 aaattattag accttggtgc ttcacccagc caagattgat ttaattccca gctgacccag
    15361 ttgggaattc ctttatctct attgtatgaa agaacatatt gaggtttttc tattaaataa
    15421 ttatttgggt ccgtttgact ggcattactt ggattaccaa atggtaagcg agggttagta
    15481 gcaagcggtc ttggaaaaag aatcgtacat ccgacaacca gtgtcaggag aagtgtgatt
    15541 agcagaatga gaagtttttt ggaggcgaac attatcttcc aatacagtgt attgcaggcg
    15601 cagtttgcag acagtttttt agatattggg gattaacgct tctcaagcac ggttctcatt
    15661 agaacatcaa ccctaaatat aaaagctgca tcgtacccaa aacgaaccct tgagggcggg
    15721 gagttagtca atgttaccat tttagcttaa tccaaaattc attttatatc cgatccttta
    15781 agttagatat taggatgaat tttgggatac aatttgctcc tcgccgttgt tgaagaatta
    15841 acaacatctg tctcaaaaat agttttgtat aaaatacaac acaacttttt gggtaacacc
    15901 actaaaacac aaacagaata agctatgtta gctttttata aaaataattc ttttcaatct
    15961 gtatgataga taaattagtt aagggtgagg agcatcccta tttggaaaaa atacatttgc
    16021 gattgaaatc gctactatac aacctaagtc cgcctacgcg gactttttat taagtccacg
    16081 taggtggact ttgtttgtgt agccccatat ttttaatatg agggcaattg gcattcttag
    16141 ggatgctccc taaagatgta gccaaagaag taaccaaaag catcattctt taattctgta
    16201 aatttctact ctacctgctc tcttcatttt tctctctaga gtgatatcta tggttaattt
    16261 aagtcttata cgttcgacct taattgcaaa tgcagttagt ataattagtc tggcaagtct
    16321 tctactagtg ccatcccaag ctgctgttat aaatggtaat tttgataatg atttgaagaa
    16381 ttgggaagct aaaggtagcg ttaatcttat cgatggacaa gcattaatgt cagcttatgg
    16441 agatgatgtc acagtagttg aaacattcct agaactaagc gatggaacat tgaatgctgt
    16501 aaacagaacc tctgcagcca atggctctgc aatcaaacaa acaattacag ttaatgctgg
    16561 agatatattg agctttaatt ggaaatttca aggaggagat tatttgccat ttaatgattt
    16621 ttccttctat tcaattaatt caatagctta taagctggct gatatcgcgc aagttggtag
    16681 ttttgaagaa agctcatccc agactttcca taccttccaa acagcaggta cttacaccat
    16741 tggatttggg gttttgaatg ccttagatac ttcgggtacc tcatttctgg caattgataa
    16801 cgtcaaagta tcatctacca ccactgttcc cgaacccgct tctataattg gtattttaac
    16861 aataagtgct ataagtggaa cttcggcttt aaagcgcaaa cagcttgtaa aagctagaca
    16921 aaattgagaa ataggattct aatacaaatt ttctatgaac atgcatacaa ttagactgcc
    16981 ttcgcagtct aattgtatag ccccgctctt ctaaagtgag agcaagaatg tacaacttaa
    17041 catagaattt gtatgaaatt agtttcatga attaagtgat gagagatttt catgtatgta
    17101 gtcgtttact tgggttttgt ggcatggtat tatagaaatt tagtggaaaa ttgcattatt
    17161 attatgacaa cttctacagg gaagtttctg gcgacacata gactggtatt ctcactcttt
    17221 gtcactagaa gctaacagtt ctagagcttt ttatctctgg ttgcgagaga gttcggaaaa
    17281 gacaagataa aatctttaac ttgagctttc ccccgattct tgattgaaca attagtaaaa
    17341 aaattataaa tatctaagga attttatata taaacctgat attctgttga gaaaattgtt
    17401 agatatttct caccaaattt taacaattag tatttcctga aagaatttct ggtttatgat
    17461 aaaagccatt gaaaagaaaa ctttacaaaa tcaaatgtgg caacgctctc gacaagcgat
    17521 cgcacttttg tcttctttaa actatcgaac tggggaatta agcagctatc tacataacgt
    17581 tgcttgtgga gtcagtgagt tactgaatgt agattggtca gtcgtaacat tttgtcaaga
    17641 aggatttgaa aaggtactgg ctagtagcat tgatatcggt gagggcgaac acctttattc
    17701 actgcatggt tcattaacag gcactgttgt aaaaactggt tgctccctag tagtgaaaga
    17761 tgcaaaggaa cacccagagt ttggcgaagc tccagaaggt tataacgctt atttaggtat
    17821 accgttgcga actgctgaag gcgaagtcat tggtacgatt tgctctttcc atcagcaacc
    17881 gcgagagttt agcgaggaag agattcagtt aggcgaactg tttgctgaac gtgctgctac
    17941 agcaatcgat aattatcatt tgtacaaaca acaatgccaa tttaaccaga ttctggaggc
    18001 tgaagtacaa aaacgtacag aagaattacg gacagcacaa gccaagcttg tagaacagga
    18061 acgcctagca gccattggtg aatttgcggc aatgattgtt catgaaattc gtaacccatt
    18121 gactacaacg atcttaggat tgaagtattt ccaaaaaacc gttttaactg aatccgccaa
    18181 agagcgatta tcattgtcgc tcaatgaagc cagtcgatta gacaatctgc tgagtgaaat
    18241 tttgctttat gccaaacccc aggtgttgca actgtgtgaa ttggatgtag atcgattcat
    18301 gagtgagttg ctcaatgaca tgagcgagat gcaagaagcc gttgcacgaa aaattgaatt
    18361 gatccctgta tcagttccag tcaagatttt gggagacaaa gataaactca aacaagtttt
    18421 tattaatatt gtccgtaatg cctgtgaagc agtttcccca ggagacgcca ttaaatggga
    18481 agtagacatt tccgatccag agcaagtttg catcaatgtt tgcaataagg gtcaaccaat
    18541 tcccccagaa gttttgtcaa aactaactca gccattcttc tctacaaaac caagtgggac
    18601 tggtctaggg ctggctatca ccaaacgcat agttaatgct catggaggag aattatttat
    18661 tcactctgat acaacaggta ctacagtcag cgtgcaatta cccagaattc atcttttgga
    18721 ctttggacaa aaaaatcaca atctatccgt ttttatttag tatcaaatca aactaaactt
    18781 gagagcgtta atgtaaaaaa atgtagggga tgatcggcga tcgcactcaa gaaacccagg
    18841 taaaaatttt tttatgtatg ttgttgtcta tatgttgtaa gccgagcagc gaagcttatc
    18901 gccctgattc gtgtaacaat taatcccacc tgcgtaactt ttggtgtacg gtagctaagt
    18961 gccacatata atcgtcaatt ttataactaa ctgcttgagt catatattgc cgtgcttgtt
    19021 ctagttgact ctctacttca aaatacaaac taagataaag ataactataa aacgattgac
    19081 gccgatcgtt agaagcgcca acagccagga catcatcaac agagcagtga ccggcataaa
    19141 aatcgtaaac tcgccgcatg acaaaccggg aatcgtttct gacttctaac aaagactgtc
    19201 gtgcttgtgt gggaccgtga aggcgagcaa tgcaaaggta gcgccaaacg gtttcttcca
    19261 catcgtgaga gttaatagtt aagtctatct caaattgttt tgccccctca gcaaatcgtt
    19321 cggcgtagta gtacgacaat cctctttgcc acaagtaggg tgttaagcgt gggtctagtt
    19381 tttcagctgt atcaaagtca gcgatggatt catgaatgtt acctaacttg aaatgaacca
    19441 ttccccgata tatgtaggct ttggggtcat gaggatgact ggagataaca ttattccaac
    19501 gaattagctc ttgttctaga agattgctcg aattcattat caatattttt ataaatagta
    19561 ctgcctgaaa aatggcaaag tcaggctatt tacatagaaa actgtcaaag tcaagatgaa
    19621 gataagaaag aacatcttca agtctttctg caacaatatg cgccactcca aaaaatggag
    19681 ttattgcagg attgcttggt atataattga gcaacttatt tccaaaagtt ttgcgaaaag
    19741 actcttcatc tatcgaatat tttccagtct cataatgcgg tggcaaactg ccaagaacaa
    19801 aggcataaat attggaagaa tcttcttcag ctagcaaaga atcccaatcc gggcttcgat
    19861 ctgtgaagaa aagttcgtaa ggattgaaat taaaagtata ctctgtcaaa tctgggagag
    19921 caacttgccc aaaacgcagt gggtttaact caatgggaaa aagactgccg tcactgtacc
    19981 ttctaaactc aaaatggaat gggaagcgat gcaaatcgag cttggttccg atcttatcca
    20041 taaggcgagt aagaggttct agtgtctgag ctacaacttg ccttgatgta tagtagagag
    20101 tatcactcac atctgattcc gaggcgaaag gatggtgata caccccagtt atgactgttc
    20161 tgccgtttgc atcccagaag ccatcgcaag caaattcctc gccttctacg aactcttcca
    20221 ccagaaaacg cgaactgctt agcatagcgg aattcataga ctttgtagcc ctgtcgatat
    20281 cctgaagaac cgaatctact gtgcgagccc actcttgttg tcctcgcact gtgcgaatac
    20341 ctatggaggc ggttcctaaa gaaggtttga gtaccactgc tttaatttcc tgtggtagct
    20401 gaaagtcttg cagagtttct cttgttaact ctacgtagaa taaatcggga tgtgattctt
    20461 tgaggagttc tcggaaagcc gctttgtctt taaagacatt cacttgagac aactgtgtgt
    20521 gtgaaagatt ttggagaatg aaacagaggc ttgcttccca gttcattatg accgcagtgt
    20581 ctctgtttgc taccaaagac tttgcttctg tatcttcaag tgtaggaatt gtctctggta
    20641 gaggcggtgt tggtggttgg acatacacgg gaattgcata tttttgcacg gcgcgtagca
    20701 atgagggaga aagaacgggt ccggagatca aacagcaatt taagctcata tatccaataa
    20761 accgtagcgc ttttgtaaat tgagcaactt cattctggct tcacctgcat tatcggctag
    20821 atcggcaaat tcaacaaatc tcagtaattc cttccgcagt aaatttcgct caacttctaa
    20881 agtattccta tcgagatctg gtggtaaaac gatcgtgtca aatatgg
//
