LOCUS       NZ_CP009287            21428 bp    DNA     circular CON 26-APR-2024
DEFINITION  Paenibacillus graminis strain DSM 15220 chromosome, complete genome.
ACCESSION   NZ_CP009287
VERSION     NZ_CP009287.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus graminis
  ORGANISM  Paenibacillus graminis
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 7166464)
  AUTHORS   den Bakker,H.C., Tsai,Y.-C., Martin,N., Korlach,J. and Wiedmann,M.
  TITLE     Comparative genomics of the Paenibacillus odorifer group
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7166464)
  AUTHORS   den Bakker,H.C., Tsai,Y.-C., Martin,N., Korlach,J. and Wiedmann,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2014) Food Science, Cornell University, Stocking
            hall, Ithaca, NY 14853, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method :: HGAP and Quiver: SMRT analysis package v. 2.0
            Coverage                          :: 136x
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000758705.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 01:34:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,297
            CDSs (total)                      :: 6,174
            Genes (coding)                    :: 6,104
            CDSs (with protein)               :: 6,104
            Genes (RNA)                       :: 123
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 51 of 70
            Pseudo Genes (internal stop)      :: 7 of 70
            Pseudo Genes (multiple problems)  :: 16 of 70
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:17:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5609139
            Orig. end                         :: 5630567
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009287.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21428
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="13"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21428
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21428
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11428](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11428)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(341..1243)
                     /gene="secF"
                     /locus_tag="PGRAT_RS24215"
                     /old_locus_tag="PGRAT_25395"
     CDS             complement(341..1243)
                     /GO_component="GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017813438.1"
                     /locus_tag="PGRAT_RS24215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25395"
                     /product="protein translocase subunit SecF"
                     /protein_id="WP_042267331.1"
                     /transl_table=11
                     /translation="MRFKKELDFVHLSRFFYIFSIAITVAGLIFLATMGLNYSVDFKAG
                     SNVDVALSKNITLEQLKPALKDLGISHEPDITLGENRVNIRYDKELDSNQDEALKAAIT
                     KLDDKASFEINTVDTEMAKELARNAIYSVLISCLGIIIYVSIRFEWRFALAAIVALVHD
                     AFIVVAVFSIFRLEVDLTFIVAVLTIIGYSINDTIVIFDRIRENLRFGKQKTYEDLKAL
                     VNKSVAQTLMRSLYTAFTVFIAAFFLLVMGGESIKMFSLAMVIGLLFGAYSSIFIASPL
                     WLLLKKRQKQTVKSNPTKV"
     gene            complement(1233..2486)
                     /gene="secD"
                     /locus_tag="PGRAT_RS24220"
                     /old_locus_tag="PGRAT_25400"
     CDS             complement(1233..2486)
                     /GO_component="GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010347637.1"
                     /locus_tag="PGRAT_RS24220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25400"
                     /product="protein translocase subunit SecD"
                     /protein_id="WP_036702673.1"
                     /transl_table=11
                     /translation="MKRMLSFIITVLVLTGVMAFTTPGLLDKVRLGLDLKGGFEILYHA
                     EPMEAGAELSRASLQKTAESLEKRANALGTSEPEVTTEGTDRIRLKIAGVTDEAEVRKK
                     MKEPAVLTFRSAAEGDPQGTYSKIELVGSDFVEGAAEVQRNNLNQPEISIKIKDKDKFA
                     EITKRLLGKEMAIYLDDQLLGNPPVVRAVLTDGTASISGHYTIDGARELADTINLGALP
                     LKLTEKYSQSVGATLGKQSLDQTIKAGLVGSVIILIFMIGMYRLPGLLASFALILHTWL
                     LIAVFVVADFTLTLPGIAAFILGIGMAVDANIITNERIREEMRSGKSILSSVKAGNKTS
                     FRTVMDANVTTIIVAAVMFAFGTGAVKGFALILIVEIVLSIVTNLYFAHWLLTVLVKAG
                     ALKKPKQFGVKESDIRAL"
     misc_feature    complement(2679..2694)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     gene            complement(2704..2958)
                     /locus_tag="PGRAT_RS24225"
                     /old_locus_tag="PGRAT_25405"
     CDS             complement(2704..2958)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909074.1"
                     /locus_tag="PGRAT_RS24225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25405"
                     /product="post-transcriptional regulator"
                     /protein_id="WP_025702970.1"
                     /transl_table=11
                     /translation="MESEEWSYEQLSDEIEAMCRSKAEEFRLLGYEYVTGKDIWDCVSR
                     NYYKEGRPALHKLVNDIYSLKANSYMNYLTIAAYRGLNV"
     gene            3134..4732
                     /gene="spoVB"
                     /locus_tag="PGRAT_RS24230"
                     /old_locus_tag="PGRAT_25410"
     CDS             3134..4732
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoVB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909073.1"
                     /locus_tag="PGRAT_RS24230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25410"
                     /product="stage V sporulation protein B"
                     /protein_id="WP_025702972.1"
                     /sec_met_domain="Polysacc_synt (E-value: 7.7e-33, bitscore:
                     112.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKQSFIQGTLILLAAGIINRMLGFIPRIILPRVIGAEGVGLYQL
                     GYPFFIVLITIITGGIPLAIAKMVAEAEGEGRPEESRRILHSGLALSLGLGVFFTLLAL
                     AGASWVSNVILTDSRVYYTFVSMTPMIAIVAVSAIYRGYFQGRQNMIPSALSSVLESVI
                     RIVFMLWFSWLLLPRGVAYAAAGAMLGVTVGEIAGMLAILWQYYFIVKRDKKADLSPIA
                     TPPIPVPENPQKTASSAKNHSIFKRLIRISVPVTAGRLVGSFSYLLESIITARSLALAG
                     IATAAATAQYGSLQGMVIPLLLLPGVLSSSLAVSLVPSLSEASARRDLPTIHKRMHQAL
                     RLAMVTGAPFAAVMYIFAVPLCTLMYGNADTAPMLRMMAPFALFLYVQAPLQAALQAME
                     RPGRALVNTLIGAVVKIALILLLASQPEYGIYGAIIAIIVNSILVTLLHGFSLVRLISL
                     SLRLADPLKTLAAMIIMAAGMSYIYTSVPIATAQWAQFLFASASGMALYFGICLLSGLI
                     SIRDLDRVPFIKKWR"
     gene            complement(4737..5504)
                     /locus_tag="PGRAT_RS24235"
                     /old_locus_tag="PGRAT_25415"
     CDS             complement(4737..5504)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909072.1"
                     /locus_tag="PGRAT_RS24235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25415"
                     /product="DUF421 domain-containing protein"
                     /protein_id="WP_025702974.1"
                     /transl_table=11
                     /translation="MFQHISGRILMTVLMYIFIFLCMRIMGKREIGKLSVFDLTISIMI
                     AEIAIFSIEDIERPIYDGLVPMATLVLIQVLVAQFSLKSRKLRLLIDGKPSILISNGKL
                     HRGEMRKQRYNIDDLLLQLRGQNIDSPADVEFAILETSGQLTVIEKNKGISSSNQSGNS
                     SSTADARNKNEPSEGTIAGSVKLPSHKIRYEGLPIPLIMDGKVQDHNLEMIGKTRFWLR
                     TQIRQKGVSDFRDVFLCSINHKGEIYVDRLDLR"
     gene            5737..6129
                     /locus_tag="PGRAT_RS24240"
                     /old_locus_tag="PGRAT_25420"
     CDS             5737..6129
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909071.1"
                     /locus_tag="PGRAT_RS24240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25420"
                     /product="TIGR04086 family membrane protein"
                     /protein_id="WP_025702976.1"
                     /transl_table=11
                     /translation="MYLIRRLFSWRISSPVLSGLCRAFLWMLLGAMVLSLLLWGSGLEE
                     QDLTMYTYIVHGIAAAFGGLTAGRRASGKGWYHGGITGAFYGIIVLLIGFLALDSAPAG
                     IDCLWVLAAAGIAAFGGIFGVNLHKS"
     gene            6220..7059
                     /locus_tag="PGRAT_RS24245"
                     /old_locus_tag="PGRAT_25425"
     CDS             6220..7059
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909069.1"
                     /locus_tag="PGRAT_RS24245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25425"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_238326718.1"
                     /transl_table=11
                     /translation="MLYQSMNYIMLYTVIIVTVLMWLGARRNPLLAFVEIGRELVRSYK
                     FLLLVAGMFGVLAVNKYELQIEKKLHITSDYTSFVFGLEGHFVRDLQHLFFAPWLTPII
                     VFFYIFMLQAVLAASLGVYLLDKNRVMLYATCYAIILNYAIAIPFYLYFPVNEVWSYVP
                     AGVRFTMLDVFPRFEQEYRPLSGLDNCFPSLHTAISVSTALLAFRSGNRRWMAITTVSA
                     VTIVFGIFYLGIHWLTDMLGGTLLAVLSTTVAVQLAKLTLRSGEGRLTLRSRATDTH"
     gene            complement(7145..8488)
                     /locus_tag="PGRAT_RS31850"
     CDS             complement(7145..8488)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="PGRAT_RS31850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_025702979.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 6.2e-19, bitscore:
                     66.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGHNPIDVCLIDDGVNEYPFDIGTLKYNKEIKDNLKIINRNHYD
                     QHQKSHGTVCAGIIKKYAPAARLSSVKILNDKNNRKGTTKQLITALYWCLDNHIKIVNL
                     SLGSTYFLDFAAIRDCVNDVAEQGIIMVAASNNNGLFTLPASLTNVIGVKSSGDLHSNQ
                     YVFDPYPYDGIDVITSGKHSIPSEQGEVFETNSSNSFAAPFITGRVHEILTKHPFFTLD
                     DIKTELNNNSISNESSYNPCLMINTDWMIKEKEYTISNLKDGVYEIGMLPQGNMNEHKV
                     KIWSSEFYGSYIRELLKKMKTVDPPVPVILIRGFLRKEFSIALDHFFHKDKFYPVRISD
                     HSSDIFDGFEYLPEETGFLAFFGFIHQKYKCDVIIFVSEASDSDGFGDYPFDITINLLE
                     RNYSNKKHFVYDYNPQEELMDVSIYLDHKTLSKDVRTTYKSLRKVLTS"
     gene            complement(8499..8795)
                     /locus_tag="PGRAT_RS24255"
                     /old_locus_tag="PGRAT_25435"
     CDS             complement(8499..8795)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04069.1"
                     /locus_tag="PGRAT_RS24255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25435"
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="WP_162165049.1"
                     /transl_table=11
                     /translation="MGIISQEINAIEIAESLDEILKNKLLIDTDLWGQDKYNRNFLERD
                     VNMKARHLLKLYFEIEENFGISIPEKDIVSGEFNTISNISAIILREIKNKTTR"
     gene            complement(8845..9981)
                     /locus_tag="PGRAT_RS24260"
                     /old_locus_tag="PGRAT_25440"
     CDS             complement(8845..9981)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04066.1"
                     /locus_tag="PGRAT_RS24260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25440"
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="WP_025702983.1"
                     /transl_table=11
                     /translation="MNKESVLIYPYDSHFTPLLRDKGFVDHYGNIQLSSLPGWGLCGKD
                     ASYADGGGFLGLTVSQEFEQLLSGIDTVIFAEADNSYTLDKNIYPKLLSAVEAGKNIIT
                     LLPLNEKLEEIQGKCEKKGSYFINYGENNLNHTDFLNDLSSGQKEIIDCTTPILAVVGI
                     AENTHKFQMQLDLKSTFESMGYKVSVVGTRSYCEFLGFHSFPGFMKELISESDKILCYN
                     RYIKQIESTEEPDLIIVAVPGGFMRYNNKITNDFGITAYEIFQAVVPDAVVVSLFHEKY
                     TAEYLDGIMKSVKYKFGLDIDALNITNRQIDWVEMTNSKPSSVNTLTLNQDFMQNSIEE
                     CGVLSSVPVFNALDKGDTVKIANLIVDKLSETEMAVNF"
     gene            complement(10001..11428)
                     /gene="ccpM"
                     /locus_tag="PGRAT_RS24265"
                     /old_locus_tag="PGRAT_25445"
     CDS             complement(10001..11428)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="ccpM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04068.1"
                     /locus_tag="PGRAT_RS24265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25445"
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="WP_051424671.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.3e-16, bitscore: 59.3, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 4.8e-48, bitscore:
                     162.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-09, bitscore: 36.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTKENPLIYSFENMDKYYFFDVNKNKIINVDEETYQIINDPEAI
                     RSSEHPVIQKLMDQGYLSNNRVEEIKHNNGRMLDELLGYNLKKIILQVTQNCNFRCNYC
                     VYSGSYVNRVHSNKRMDFATAKKGIDFLIEHSKDAKDIDISFYGGEPLLEMNLIIQCMD
                     YAIKAAEGKNVSFSLTTNGSLLTEANVKRLLGYNLRITVSMDGPQEIHDKHRTFASNGC
                     GTFNAVYDNIKRIVEKYPAIKKNLSFSMVMDPTAQFNCLDEFIASEEEFFNESAVIGSF
                     VSNNYRNDRVQFSENFVGEWEYSKFKYLLFVLGKVSKANNSQLIRAAYREHFEYISNSH
                     RNIAPLAKQDHHSGPCVPGQIRLFMSTDAHFYPCERVSETSDIMRIGNIEEGFFFDKIE
                     KLLNVGKLTEENCKECYAFRNCRVCASLSDDGNQLSKEAKLKACQDVRYNFDEMLKDVC
                     TLKECGLRKEMVQKITG"
     aSDomain        complement(11066..11422)
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PGRAT_RS24265_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="6.10E-19"
                     /identifier="RREFam021.1"
                     /label="PGRAT_RS24265"
                     /locus_tag="PGRAT_RS24265"
                     /protein_end="121"
                     /protein_start="2"
                     /score="59.3"
                     /tool="antismash"
                     /translation="TKENPLIYSFENMDKYYFFDVNKNKIINVDEETYQIINDPEAIRS
                     SEHPVIQKLMDQGYLSNNRVEEIKHNNGRMLDELLGYNLKKIILQVTQNCNFRCNYCVY
                     SGSYVNRVHSNKRMD"
     gene            complement(11802..13562)
                     /locus_tag="PGRAT_RS24270"
                     /old_locus_tag="PGRAT_25450"
     CDS             complement(11802..13562)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="PGRAT_RS24270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25450"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_025702987.1"
                     /transl_table=11
                     /translation="MKSIVDKKDIGLLKRCLMYLFPYKLRVITTFFCIVFCLILQIIEP
                     LILGKVIALLFSKEFEKLSVMLMYLFVTELFVTILSFFQSYLFSSLSENIIYDLKRDMF
                     QKIIELPVKAFDQMKVGEFISRLQGDTATVAGILTNQLINTAIDILRVVIISIVVFQIS
                     IPLSLVIVLSFPVTFLIFTFSGKKIRKRSEELAKLNDSYFSNLQQSITGIREIKSLGIK
                     KIKINQFLDLAILLKEKNININIISTVARSLSQFTSFLSQLSVMAIAGFLIYKGQLNIE
                     YFIAFTSYSSQLTGSLMNITQISSNIQKALTSLERIFNLLDEFGYKREKFGDIEKQYIE
                     GEIKFCNISFGYGDDLRVVDDLSFSIAKNNTTAIVGSSGGGKTTIFNLLLHFYEADTGA
                     ILIDGTDIKHFNEETLRRHISVVHQTPYLFNATFAENMLIANQEATEEDMITICKKIKI
                     HDYIMSLPHGYKTVIEENGSNLSGGQKQRIAIARAMLKKSKIILFDEATSSLDNETQQM
                     VKELISSISHDHTVVVIAHRLSSIIDSDEILVIDAGKLVGQGSHRNLLNNNFTYKKLYE
                     SELECRALIS"
     misc_feature    complement(13623..13636)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.77"
                     /tool="antismash"
     misc_feature    complement(13928..13942)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.44"
                     /tool="antismash"
     gene            complement(14008..14319)
                     /gene="yajC"
                     /locus_tag="PGRAT_RS24275"
                     /old_locus_tag="PGRAT_25455"
     CDS             complement(14008..14319)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="yajC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909067.1"
                     /locus_tag="PGRAT_RS24275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25455"
                     /product="preprotein translocase subunit YajC"
                     /protein_id="WP_025702991.1"
                     /transl_table=11
                     /translation="MLQFQYAAASGGGSILGLVGPFVLMFVVFYFLLIRPQQKKTKTRN
                     AMLKALKKGDKVVTIGGLHGTIMEISDDIVVLRVNDVTKLTFDRGSISHSVVEVEDKE"
     gene            complement(14363..15499)
                     /gene="tgt"
                     /locus_tag="PGRAT_RS24280"
                     /old_locus_tag="PGRAT_25460"
     CDS             complement(14363..15499)
                     /EC_number="2.4.2.29"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tgt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) bTGT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016819139.1"
                     /locus_tag="PGRAT_RS24280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25460"
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="WP_025702993.1"
                     /sec_met_domain="bTGT (E-value: 1e-203, bitscore: 674.6,
                     seeds: 1816, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAITYEHIKTCKQSGARLGRVHTPHGIIETPAFMPVGTLATVKT
                     MSPEELKQMDAHIILSNTYHLFLRPGHDIIREAGGLHKFMNWDRPILTDSGGFQVFSLS
                     DMRKITEEGVHFRSHLNGDKKFLSPEVAMEVQNALGSDIMMAFDECPPYPAEYDYVKKS
                     LERTTRWAERCLKSHARPEDQGLFAIVQGGMHEDLRRQSAADLTSMDFPGYAIGGLSVG
                     ESKQLMYEVLDYTVPLLPQGKPRYLMGVGSPDALLEGSIRGVDMFDCVLPTRIARNGTT
                     MTSQGRLVVRNAQYARDFGPLDPECGCYTCRNYSRAYLRHLIKADETFGLRLTTYHNLY
                     FLLELMRKVREAIREDRLLDFRDEFFAQYGLYDNLKGF"
     gene            complement(15521..16549)
                     /gene="queA"
                     /locus_tag="PGRAT_RS24285"
                     /old_locus_tag="PGRAT_25465"
     CDS             complement(15521..16549)
                     /EC_number="2.4.99.17"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="queA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016819140.1"
                     /locus_tag="PGRAT_RS24285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25465"
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="WP_025702995.1"
                     /transl_table=11
                     /translation="MNVDDYDFHLPEELIAQTPLSDRSASRLLLVNKENGQLEHRHFTD
                     ILEQFQPGDTLVLNDTRVIPARLFGVKEDTGAKAEVLLLKNLGEDRWEALVKPGKKLKT
                     GAVIIFSEELRAIIEDEADMGGRTLRFIYTGIFQEILDRLGSMPLPPYIKETLDDRERY
                     QTVYAKHEGSAAAPTAGLHFTRELLEQIKAKGVTIAYITLHVGLGTFRPMSVEKVEEHV
                     MHAEYFVLSQETADVLNAARARGGRIIAVGTTSCRTLETVGRQAEGGPIQECSGWTDIF
                     IYPGYKFTVVNALITNFHLPKSTLVMLVSALAGRENILAAYEAAIQQQYRFFSFGDAMF
                     IY"
     gene            complement(16559..18643)
                     /locus_tag="PGRAT_RS24290"
                     /old_locus_tag="PGRAT_25470"
     CDS             complement(16559..18643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909064.1"
                     /locus_tag="PGRAT_RS24290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25470"
                     /product="SpoIID/LytB domain-containing protein"
                     /protein_id="WP_025702997.1"
                     /transl_table=11
                     /translation="MNLAKWKKTGMSLLAGALMTGGLLLPAADSHADPNATIRVALYAD
                     IGSKYKSTVPFVTLSSTVGFSLMSGSTPLLPIPANNRIRISLDGYKVKVMDSPTWQAAA
                     EAAKKLQSTSDKPMLFVASRNGATVYQLYTGPYTSESAAREGLNRVSKAGLSLAEGQTP
                     ALAGSKHLSAGSFATLEEADAVVSTITAAGFDAWKTLTSGPAGSAQVEVWVGEAASDSD
                     LAALRTAVTAALPQLAVSAGATTTPGMMIRTDAGLDWSSESQAFHYQVSGTGAKFMASG
                     NSAGIQIAERSKRIYRGNLELSGLAGSLAVINEVPLEQYLYAVVGGEVSSGWPEEALKA
                     QAVAARSYALSQGNRFDVANVVDTTLSQVYNGIGAEAPVITKSVDATAGEVLMSGSKIV
                     EAVFSSNSGGVTADPSEVWGNGGTTFVSVASAEDSAAAAASKKWYYLLLDSGVSGYARE
                     DNIQLTGSKTASGLVIATASTKDVNIRPLPVVESGASPLGKLNPGENAVVLDQFYENGS
                     YSWVKGPYTSAELLKSLSGKVSSSLPSSISSLQVSQRGPSGRVTQVKANGEILQVKYPD
                     LFRSAFGGLPSTLFDIVPAGSYTVLGADGSTSTVDSSQSAGVLSASGKVTANGSGTVVM
                     GADASSRVVTTSPGFYFIGWGNGHGLGMSQWGVKGMADKGYDYKQILQHYFNNVTIVKE
                     "
     gene            complement(18685..19692)
                     /gene="ruvB"
                     /locus_tag="PGRAT_RS24295"
                     /old_locus_tag="PGRAT_25475"
     CDS             complement(18685..19692)
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0009378 - four-way junction helicase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="ruvB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311578.1"
                     /locus_tag="PGRAT_RS24295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25475"
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="WP_020426618.1"
                     /transl_table=11
                     /translation="MDDRIISANLMMDEQAVELSLRPRYLGEYIGQNQVKENLKIYIEA
                     AKMRSEALDHVLLYGPPGLGKTTLANIIANELGVNLRTTSGPAIERPGDLAALLTNLQQ
                     GDVLFIDEIHRLHRTVEEVMYPAMEDFALDIMIGKGPSARSVRLDLPPFTLIGATTRAG
                     LLSAPLRDRFGVVSRLEYYTIDELSFIVSRNAELLGIEILGDAAEEIALRSRGTPRIAN
                     RLLKRVRDFAQVRGDGIITPEIAGESLKMLQVDPRGLDSIDHKMLHSMISSFRGGPVGL
                     DTIAATIGEESQTIEDVYEPYLLQIGFLQRTPRGRVVTPAAYQHLGLPLPPQPQ"
     gene            complement(19722..20345)
                     /gene="ruvA"
                     /locus_tag="PGRAT_RS24300"
                     /old_locus_tag="PGRAT_25480"
     CDS             complement(19722..20345)
                     /EC_number="3.6.4.12"
                     /GO_component="GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA]"
                     /GO_function="GO:0009378 - four-way junction helicase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="ruvA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019909061.1"
                     /locus_tag="PGRAT_RS24300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25480"
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="WP_025702998.1"
                     /transl_table=11
                     /translation="MIDYLRGPVVHLEPEYVVVDVQGIGYRVFCPNPYAFAKLEGPVTV
                     YIHYQTREDATLLFGFPTREEQKLFRKLIEVSGIGPRVALGILTGGTPDQLISAIYQEN
                     ITFLTKLPGIGKKTAQRMILDLRDKLDGLSAVSMQTGLFAVAAEAQAAEEAMPWEEARD
                     GLRALGYTEAELDRVWLTMKKEGADTGPVDVLMKKALGLLYIAK"
     gene            complement(20342..20845)
                     /gene="ruvC"
                     /locus_tag="PGRAT_RS24305"
                     /old_locus_tag="PGRAT_25485"
     CDS             complement(20342..20845)
                     /EC_number="3.1.21.10"
                     /GO_function="GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="ruvC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431677.1"
                     /locus_tag="PGRAT_RS24305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PGRAT_25485"
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="WP_025703000.1"
                     /transl_table=11
                     /translation="MRILGIDPGLAIVGFGFVDKAGNKLTPVQYGCIQTEAHTPEEERL
                     LHVYEGMVQLIDKYQPDAVAVEKLFFSRNVTTALPVAQARGVLILAAVQRGLPVAEYTP
                     MMVKQAVVGYGKAEKKQVQEMVKLLLKLAAVPKPDDVADALAVAVCHAHSVSLNSKLNE
                     VLRK"
     misc_feature    complement(20927..20940)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.68"
                     /tool="antismash"
     misc_feature    21361..21376
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.16"
                     /tool="antismash"
ORIGIN
        1 tggtgttacc ctcttcttct tctctggttc cctgcgccac ggaagcggaa gaatctctgc
       61 cagcttggcc gctgcatccg atcccgaata taacgcatca cccattaatg ccttactgtc
      121 tgaaagataa ccaaaggttc ctttggctgc tgccaatgca agatcaccgg caacaccagt
      181 ccagaccatt ttatcactct gcggtaattg tttgtcattc attacgaggc cctccttacc
      241 actagcaagt atctcatgat gaccgctccg cctgacattc cgctccaaag atttcgaaaa
      301 gccgcgtcgt ctttgacgcg gcttttcggg tgtgacggca ttagacttta gtcggattgc
      361 tcttcacggt ctgcttctgg cgtttcttca gcagcagcca gagcggactt gcgataaaga
      421 tcgatgagta ggctccgaag agcaaaccga taaccatagc aagcgagaac attttgatcg
      481 attctccacc catgacaagc agaaagaacg cggcgataaa taccgtaaac gctgtgtaca
      541 gagagcgcat aagcgtctgg gccacacttt tattgaccag tgccttaaga tcctcatagg
      601 tcttctgctt gccaaaacgc agattctcgc ggatccggtc aaagataaca atggtatcgt
      661 tgatggaata accgatgatc gtcagcaccg cgacaatgaa ggtcaggtca acctccaggc
      721 ggaagatcga aaagacggct accacgataa aagcatcatg cacaagggcc acaatcgcag
      781 ccaaggcaaa ccgccattca aagcggatac ttacataaat gataatcccg agacaagaga
      841 tgagaaccga atagatggca ttgcgcgcca gctctttggc catttccgta tcgacggtgt
      901 tgatctcgaa ggaagccttg tcatccagct tggttatcgc agctttcaaa gcctcatcct
      961 gattactgtc aagttcctta tcataacgga tgttcacccg gttctcacct aaggtaatgt
     1021 ctggctcatg ggagatgccc agatccttca gcgccggctt aagctgctcc agcgtgatgt
     1081 tcttcgacag cgccacgtca acattggagc ctgctttgaa atcaacgctg tagttcagac
     1141 ccatggttgc cagaaagatc aggccggcta ccgtaatggc aatggagaaa atatagaaaa
     1201 atctgctcag atgtacaaaa tcaagctctt tcttaaagcg cacggatgtc actctccttt
     1261 accccaaatt gcttcggctt tttcagagcg ccggctttga ccagcacggt aagcagccaa
     1321 tgggcaaaat aaaggttcgt cacgatacta agcacaattt ccacaatcag gatcagtgca
     1381 aatcctttaa ctgcacctgt accaaaagca aacattacag ccgccacgat aatcgtagtt
     1441 acgttcgcgt ccataactgt gcggaaagag gttttgttcc ctgctttgac agaagacaaa
     1501 atacttttgc cgctgcgcat ttcttccctt atccgttcat tggtaatgat attggcatca
     1561 accgccatcc ctataccgag aataaatgcg gcgataccgg ggagagtcaa ggtgaagtcg
     1621 gcaacgacga atactgcaat cagcagccag gtatgaagga tcagcgcgaa gctggccaga
     1681 agacccggca accggtacat gccgatcatg aatatcagaa taattacaga gcctacaagt
     1741 ccggctttga tggtttggtc aagagactgt ttaccgaggg ttgcgcctac gctttgggag
     1801 tatttctccg tcagcttcag cggcaaagca ccaaggttaa tggtgtcagc cagttcccgt
     1861 gctccatcaa tagtataatg accggagatg gaagcagtgc cgtctgtcaa taccgctcta
     1921 acgactggcg gattacctaa cagctgatca tcgagataga tagccatttc tttaccaagc
     1981 aaacgcttgg taatttccgc aaacttgtct ttatctttga tcttgatgct gatctcaggc
     2041 tgattcaaat tgttgcgttg aacctccgcc gctccctcaa caaagtcgct tcctacaagc
     2101 tcaatcttgc tgtacgtacc ttgcggatcc ccctcagcag cactgcggaa ggttaaaact
     2161 gcgggttctt tcatcttctt gcggacttcg gcctcatcgg taacgcccgc gatcttcaga
     2221 cggatgcggt ccgttccttc tgtagtgacc tcaggctcgc tagttccgag tgcgttcgcc
     2281 cgtttttcca ggctctctgc agtcttctgc agcgaagcac gggataattc tgctcccgcc
     2341 tccattggct cggcgtggta cagaatctcg aagccgccct tcagatcaag ccccagacgg
     2401 accttgtcca gcagcccggg agttgtaaat gccatgaccc cggttaatac gagcacggta
     2461 ataataaagc tcaacattct cttcatgctc ttgctagttc ccctttcatt actcaatatt
     2521 cctattatag ctacgtgcga aatcaccgtc aattcaagca gaaatgacgg tacggttctc
     2581 acacaaagaa acggccggcc ctgctcaagc ggcatgccat ccgttttttc ataggaaatg
     2641 ctgaatgctc ttctcttact ttaacgcttc ctgaacctgt ttgcaaaagt aaatcgttcc
     2701 tttttataca ttcaaaccgc gataagcggc aatagtcaaa tagttcatat aactattagc
     2761 cttgagtgaa tagatatcat tcaccagctt atgcagggcg ggtctgcctt ccttgtaata
     2821 gttgcggctg acgcagtccc agatatcctt gcccgttaca tattcatagc cgaggagccg
     2881 aaattcctcc gctttgctgc ggcacatggc ttcgatttca tcactaagct gttcataact
     2941 ccattcttcc gattccacgt gttgacacct ccaaagatac ctcgcttatg catgttcaca
     3001 aatagtattc gaccaggctt ccctagtttc cttcttccgg ctgaaaagtt gtcatgcata
     3061 aagcttgtca tggaaaagcc tatcatccca tatcaatgta agagagacta cttgtgggaa
     3121 gaaggagtgc cctttgagga aacagagctt tatccaagga accttgatac tgctggccgc
     3181 aggcatcatt aaccggatgc tcggctttat tccgcgaatt attttaccgc gtgtgatcgg
     3241 cgccgagggt gtaggcctgt atcagctcgg ttatccgttt ttcattgtgc tgattacgat
     3301 cattaccggc gggattccgc tggctattgc caaaatggtc gctgaagccg aaggagaagg
     3361 gcgccctgag gaatcccggc ggattctgca cagcggactg gcccttagtc tcggacttgg
     3421 tgtttttttc acgctgctcg cattagccgg cgcttcctgg gtctccaatg tgattctgac
     3481 cgacagccgg gtctattaca ccttcgtcag catgacaccg atgattgcta ttgttgccgt
     3541 ttctgcgatc tacagggggt attttcaagg cagacagaac atgattcctt cggcgctgtc
     3601 ctcggtcctg gaatcggtca tccggattgt ttttatgctg tggttctcct ggctgctgct
     3661 tcccagaggg gttgcttatg cggcggcagg agccatgctg ggtgtgacgg ttggagagat
     3721 tgccggcatg ctggccatct tatggcaata ttattttatc gtaaaaaggg acaagaaagc
     3781 agacttatct cccatagcaa caccgccaat cccagtgccg gaaaatcccc aaaaaacggc
     3841 ctcttccgct aaaaatcatt ccatattcaa gcggctgatc cggatttctg tgcccgtcac
     3901 tgccggacgg ctggtgggtt cgttctctta tctgctggaa tccattatca ctgcccgcag
     3961 tctcgctctc gccggtatcg ctacggcagc tgctaccgca cagtatgggt cactgcaggg
     4021 gatggtaatt cctttgctgc tgctgccggg ggtgctcagc tcttcgcttg cggtatcgct
     4081 tgtgccttcc ctgtcggaag cttcagcgcg ccgtgacctg cccacgattc acaaaagaat
     4141 gcatcaggcg ctgcgcctgg ccatggtgac cggtgccccg tttgctgcgg ttatgtacat
     4201 ttttgccgta ccgctctgta cgctgatgta cggcaatgcc gacaccgccc cgatgctgcg
     4261 gatgatggcc ccttttgcat tgtttctata tgtccaagca ccgctgcagg ctgccttaca
     4321 ggctatggag cgcccaggca gggcactggt caacacgctg attggagcgg ttgttaaaat
     4381 cgcacttatt ctcctgctcg cctcacagcc cgagtacggt atctacgggg cgatcatcgc
     4441 aataatcgtc aacagtattc tggtgactct gcttcatggg ttcagcctgg tccggctgat
     4501 ctcattgtca ctcaggctgg ctgatccgct caaaaccctt gcagcgatga ttatcatggc
     4561 tgccgggatg tcttatatct atacctctgt gccaatcgcc actgcgcagt gggcccaatt
     4621 cttgttcgcc tccgccagcg ggatggcgct ctatttcgga atctgcctgt tatcgggcct
     4681 aatctccatt cgtgatctgg accgggtgcc ttttatcaaa aaatggcgct gaagcttcaa
     4741 cgcagatcca gacggtctac ataaatttct cccttgtggt ttatggagca gagaaaaaca
     4801 tccctgaagt ccgagacgcc tttttggcga atctgggtcc tcagccagaa tcgcgtcttg
     4861 ccgatcattt ccagattgtg gtcctggacc ttaccgtcca tgataagcgg aatcggcagg
     4921 ccttcatatc tgattttatg gctcggaagc ttaacgctgc cagcaatggt cccttcggaa
     4981 ggctcgttct tgtttctggc atcggcagtt gagctgctgt tgccgctttg attgctggag
     5041 gatattccct tgttcttttc aataactgta agctggccgc tggtttccag aattgcaaac
     5101 tccacatcgg cgggactgtc gatattttgt ccgcgaagct gaagcagcag atcatcaata
     5161 ttataccgct gcttgcgcat ttccccgcga tgcagcttgc cgtttgagat tagaatgctg
     5221 ggtttgccgt cgatcagaag cctcagcttt ctgctcttca ggctgaattg ggctaccagg
     5281 acctgaatca gcaccaaggt tgccatcggc accaatccat cataaatcgg acgttcaata
     5341 tcttctatgg aaaatatggc aatctcggca atcatgatgg agatcgtcaa atcaaatacc
     5401 gagagcttgc cgatttcccg tttgcccata atccgcatgc acaggaaaat gaagatatac
     5461 atcagcacag tcatcaagat acggccagaa atatgctgga acatattctc ttcgctcccc
     5521 ttccattggt cacccgccgc catcgcgccg ggcaaattaa tgtaccccta ttctggcccc
     5581 tcaacctagg gaacattcgg aagacggctt attaattaat ggtaaaaagg gctttaagct
     5641 cctttcatgt actattgggg caagcccccc catacaatag ttagtaatca tatcttgtgt
     5701 actgtatcgc taaaaaaaat tctaggaggt cgtaccatgt atttaatccg gcgtctattc
     5761 tcgtggagaa tatcgagtcc agtgttatca ggtttatgcc gcgcttttct gtggatgctg
     5821 ctgggggcga tggttctctc ccttttgctc tggggaagcg gactcgaaga gcaggacctt
     5881 actatgtaca cttatatcgt acacggtatt gctgccgcgt tcggcggact gactgcagga
     5941 cggagagcat cgggcaaagg ctggtatcat ggtggaatta cgggagcgtt ctacggcatt
     6001 attgttctgc tgattggatt tctggcgctg gacagtgctc ctgccggcat cgattgcctg
     6061 tgggttctgg cagccgcggg tatcgctgca ttcggtggaa tattcggggt taatttacat
     6121 aaatcctaaa atttcaatat aatcgaatcc tgctcctgaa aatatggtaa actgaattca
     6181 tctgacttta catgcgggat caaggaggct tcgattgttt tgctttacca atctatgaac
     6241 tatataatgc tgtataccgt tataattgta actgtattga tgtggctcgg tgcccgccgc
     6301 aatcctctgc tggcttttgt ggagatcgga agagaacttg tccgctctta taaatttctg
     6361 ctgctcgttg cgggaatgtt tggtgtgctg gccgtgaata aatacgaact gcaaattgag
     6421 aagaagcttc atattacttc cgattacacg tctttcgttt ttgggcttga aggtcatttt
     6481 gtcagggatc tgcagcattt gttctttgct ccctggttga cgccaatcat tgtattcttc
     6541 tacattttca tgcttcaagc cgtattggcc gcttctctgg gtgtatacct gctggataag
     6601 aaccgtgtta tgctctacgc aacctgctat gcgattatcc tcaactatgc cattgccatt
     6661 ccgttctatt tgtatttccc ggtgaatgaa gtatggtcct atgtaccggc aggcgtccgt
     6721 tttaccatgc tggatgtctt cccgagattt gagcaggaat acaggccgct ttcaggtctg
     6781 gacaattgct tcccgagcct tcacaccgca atctctgtat ccaccgccct gctcgccttc
     6841 cgctccggca accgccgctg gatggcgatc accaccgtgt ccgcagttac catagtgttc
     6901 ggtatcttct atctgggcat tcactggctg actgacatgc tcggcggcac cctgctggcc
     6961 gtactgtcaa ccacggttgc cgttcaactc gccaaactga ctctgcgcag tggcgaggga
     7021 cggctcaccc ttcgcagccg tgcaaccgat acgcactgat agtaatagga aaaggccgga
     7081 gcccttaact gggttcccgg cctttttctt cccatttttc atttgtgatt ctaagcagca
     7141 agctttaact cgttaatact ttccgtaaag atttataagt ggttctaacg tctttgctta
     7201 gtgtcttgtg atctagatat atcgaaacat ccataagttc ctcttgtgga ttgtaatcat
     7261 atacaaaatg ttttttattc gaataatttc tttccaacag attaatggta atatcaaacg
     7321 ggtaatctcc aaagccgtcc gaatcagatg cttcacttac aaaaataatt acgtcacatt
     7381 tgtatttttg gtgaatgaat ccgaaaaacg ctaagaaacc ggtctcttca ggcaagtatt
     7441 cgaaaccatc aaagatatcg gaagaatggt cagaaatcct caccgggtag aatttatcct
     7501 tatggaaaaa atgatccagt gcaatggaga attccttcct taagaacccc ctaattaata
     7561 ttacaggaac aggagggtcc actgttttca tctttttcag cagctcacgg atataacttc
     7621 cataaaattc actgctccat atcttaactt tgtgttcgtt catattccct tgcgggagca
     7681 ttcctatttc ataaacacca tcttttagat tagatatagt gtattccttt tcttttatca
     7741 tccaatctgt atttatcatt aaacaggggt tataactgct ctcatttgat attgaattat
     7801 tattaagttc tgtttttata tcatctaatg taaaaaaagg atgcttagtg aggatctcat
     7861 ggactctgcc ggttataaaa ggagcagcaa aactgttcga actgttcgtc tcaaaaactt
     7921 caccttgttc tgatggaata gaatgtttgc cacttgtaat cacatctatt ccatcataag
     7981 gataaggatc aaatacatat tgattggagt gcaggtcgcc ggaactcttt actcctatta
     8041 catttgttag actggccggc aacgtaaaga gaccgttatt attagaggcg gctaccataa
     8101 tgatgccctg ttctgctaca tcatttacac aatcccggat tgcagcaaaa tccaaaaaat
     8161 aggttgaccc taaactgaga ttgacgattt tgatatggtt gtccagacac caatataatg
     8221 ctgtgatcaa ttgtttcgtt gtgcctttac gattattttt atcatttaag atcttaacgc
     8281 tcgaaagtct ggcggcgggt gcatattttt ttatgattcc cgcacagacc gtaccgtggc
     8341 ttttttgatg ttgatcataa tgattccgat tgattatttt tagattatct tttatttctt
     8401 tattatattt tagagtgcca atatcaaagg gatattcatt tacaccgtca tcaatgaggc
     8461 aaacatctat tggattgtgg cctttcattc tactaccact acctagtagt tttatttttg
     8521 atttccctca gaataattgc agatatgttg gatatcgtgt taaattcgcc tgaaacaata
     8581 tctttttcgg gaattgaaat gccgaaattt tcttcaattt cgaaatataa tttaagcaga
     8641 tgccttgctt tcatattcac gtcccgttca agaaaattcc ggttatattt gtcctgcccc
     8701 cataaatcgg tatctatcag caatttgttc tttaatatct catccagcga ctctgcgatt
     8761 tctatagcat tgatttcctg gcttataata cccaaattca ccatcccttt cagtaactct
     8821 atttgctatt cctgatttaa gctcctagaa attgaccgcc atttcagttt ccgataattt
     8881 gtctacaatc aaattagcaa ttttcaccgt gtcaccttta tccaaagcgt taaaaacagg
     8941 tactgaagat aaaacgccac attcctcgat gctattttgc atgaaatctt gattaagcgt
     9001 taatgtgttt acagaacttg gcttagagtt agtcatttcg acccaatcaa tttgcctatt
     9061 ggttatattc aaggcatcaa tatccaagcc gaatttatat ttgacagatt tcattattcc
     9121 atccagatat tctgctgtat atttctcatg gaacaggctt actactacag catcgggtac
     9181 aaccgcctga aaaatttcat atgccgtaat tccaaagtca ttggtgatct tgttgttata
     9241 gcgcataaag ccgccaggca ccgctacgat aattaagtcc ggctcctcag tggattcaat
     9301 ttgcttgatg tacctgttat agcacaagat cttatctgat tcacttatta attctttcat
     9361 aaaccctgga aacgaatgga accccaaaaa ttcacaatat gatcgggtac caactacact
     9421 cactttataa cccatgcttt caaaagtgga ctttaaatcc aattgcattt gaaacttatg
     9481 agtgttctcg gctatcccaa cgacggcgag gatcggggta gtacaatcta taatttcttt
     9541 ctgtccagac gacagatcat ttaagaaatc tgtatgattc aaattatttt ctccataatt
     9601 aataaaatag ctgcccttct tctcgcactt gccttgtatt tcttctaact tttcattcaa
     9661 tggaaggagg gtaataatat ttttcccagc ttcgactgca cttaagagtt tggggtagat
     9721 attcttgtcc agcgtatatg aattgtcggc ttcagcaaat attacagtat caatcccact
     9781 caaaagctgt tcaaattcct gactgacagt aaggccaagg aatccgccgc catcggcata
     9841 actggcatcc ttaccgcata acccccatcc gggtaaagag gatagctgga tgttgccata
     9901 atggtcaaca aaacctttgt ctcttaacaa gggagtaaaa tgggagtcgt aagggtagat
     9961 taatacactt tctttattca aaatacttcc ctccaaatca ttatcctgta atcttctgaa
    10021 ccatttcttt tctcaatccg cattctttta aggtacacac atccttcagc atttcgtcaa
    10081 aattgtaacg gacatcctga caggctttta gttttgcttc cttgctcagt tgatttccat
    10141 catccgacag tgaagcacaa actctgcagt tccggaacgc gtagcactcc ttacagttct
    10201 cttccgtaag ttttcctaca ttcaataatt tctctatttt gtcaaaaaag aaaccctctt
    10261 caatattgcc gattctcatg atatccgatg tttcactaac cctttcacat ggataaaagt
    10321 gggcatctgt actcataaat aaccggattt gtcccggtac gcaaggtccg gaatgatgat
    10381 cctgtttcgc taatggggca atattccggt gcgagttact gatatactca aaatgctccc
    10441 gataggcggc tctgattaat tgtgaattgt ttgctttgga aaccttgccc aatacaaaca
    10501 acaagtattt aaatttgctg tattcccatt ctcctacaaa attttcgctg aattgaacac
    10561 ggtcattgcg gtaattattg gatacaaaac ttccgatcac cgctgattca ttaaaaaatt
    10621 cttcttcact ggcgataaat tcatccagac aattaaattg tgctgttggg tccataacca
    10681 tagaaaagga gagatttttt ttgatggccg ggtacttttc cacaattctt ttgatgttat
    10741 catagacagc attaaaagtt ccgcaaccat ttgaggcaaa ggtacggtgt ttatcatgaa
    10801 tttcttgagg cccgtccata ctcacggtaa ttctcaaatt gtagcctagt aatctcttca
    10861 cattagcttc agtgagcagg ctgccgttcg tggtcagact aaaagaaacg tttttccctt
    10921 ctgccgcttt tatcgcgtag tccatgcact gaataatcag gttcatctcc agcaaaggct
    10981 cgccgccata aaaactgata tcgatgtcct tggcatcctt agaatgctcg atcagaaaat
    11041 ctattccttt tttagcagta gcaaaatcca ttcgtttatt gctatgtacc cgatttacat
    11101 aagacccgga atacacacaa taattgcatc tgaaattaca attttgagtg acttgaagaa
    11161 ttattttttt tagattataa cctaatagct catcaagcat tcttccattg ttatgtttta
    11221 tttcttctac acgattgttt gacagatatc cttgatccat taatttttgg ataaccggat
    11281 gctcgcttga acgtatcgct tcaggatcat tgataatttg ataagtttcc tcatccacat
    11341 tgattatttt atttttattc acgtcgaaaa aataatactt gtccatattt tcgaacgaat
    11401 atatcaacgg attttctttg gtcaacaatg gactgtctcc tttaccgttt tgtagtcttg
    11461 cttctgcata aggaaaaaag actagggctc taatgacagg taacgttgtc tttagaaccc
    11521 tagcatttcg gttaacctct tacttgagcg gttgcagtcg gagtatagtt ttgcgatccg
    11581 ctatccgcgc tagtattgct aacatgcaag aaatcaggac cccagcagct gcaagtggcg
    11641 caataacatg cacaagaaag atggcaatct gcgtatgcct caacggtatg catttgtgaa
    11701 aaattctttt tagttaattt tctcatttca tttcgcctcc cttcgtatgt aatagattaa
    11761 aatatataaa ttccagagtg gcgggcactc cgaaaagtat atcaactaat caatgctctg
    11821 cactccagtt cgctttcata taacttttta taggtaaaat tgttattcag aagatttcta
    11881 tggcttcctt ggcctaccag cttgccggca tcaataacta gaatttcatc tgaatcaata
    11941 atgcttgata gcctatgggc aatcacgaca acagtatgat catgagaaat tgaacttatt
    12001 aattccttga ccatttgctg ggtttcatta tccagtgatg aggttgcttc atcgaataat
    12061 attattttcg attttttcaa catcgctcta gcgatggcta tccgttgttt ttggccgcct
    12121 gacaggttgg agccattctc ttcaatcacg gttttatatc catgcggaag actcatgatg
    12181 taatcatgaa tctttatctt tttgcaaatg gttatcatgt cttcttctgt tgcctcttgg
    12241 tttgcgatca acatattttc agcaaaagtt gcattaaata agtagggagt ttggtgtaca
    12301 accgatatat gccggcgcag tgtttcttca ttaaaatgtt tgatatccgt tccatctatc
    12361 agaatggctc ctgtatcagc ctcgtaaaaa tgcagcagta aattgaagat tgtagttttc
    12421 ccgccgccgc tgctgcctac tattgcagtt gtattattct ttgcgattga aaaactcaag
    12481 tcatccacaa cccgcaaatc gtccccgtaa ccaaaagaaa tattacaaaa tttaatttcc
    12541 ccttcaatat attgcttttc tatatcgcca aacttttctc ttttgtaacc aaattcatcc
    12601 agtaagttaa atattctttc cagtgaagta agcgccttct ggatgttgct gctgatttgg
    12661 gtaatgttca ttaatgaacc cgtcagctgg ctggagtaag aggtaaacgc aataaagtat
    12721 tcaatgttca gctgcccttt atatattaga aatcctgcta tagccatgac actaagctgg
    12781 gagagaaatg aagtgaattg ggataatgac cgggccacag tgcttataat atttatattt
    12841 atattttttt ctttaagcag gatggccaga tccagaaatt gatttatttt tatcttctta
    12901 atgcccaaac tcttgatctc tctgatcccg gttatggact gctggagatt actgaaatag
    12961 ctgtcgttta gcttagccag ctcttcactt cgcttcctta tttttttccc ggagaaggtg
    13021 aatataagga atgtaaccgg aaagcttagt acaatcacca aagatagtgg aatactaatt
    13081 tgaaacacaa caatgcttat gatgacaact cgaagaatat cgattgcagt attaatcaac
    13141 tggtttgtaa ggatgcccgc tacagtcgca gtatcccctt gcaaacggga tataaattcg
    13201 cccaccttca tttggtcaaa agcctttaca ggaagttcaa tgatcttttg aaacatatct
    13261 cttttcaagt cataaataat attttcgctt aatgaggaaa ataaatagga ttgaaagaaa
    13321 cttaaaatgg ttacaaaaag ctctgttaca aacaggtaca ttagcattac actcagcttt
    13381 tcaaattcct tagagaacaa taaagctatg accttaccta atattaatgg ttcaataatt
    13441 tgcagaatca gacaaaacac aatacaaaaa aaggtagtaa ttacacgcaa tttgtaagga
    13501 aagagataca tcaaacatct ttttaacaaa ccaatatcct ttttatcaac tatcgatttc
    13561 ataagtcgta cctctgatgg taaaatttaa tcggtatatt atttatttca taatcttaca
    13621 ctttgtaata attttcactt gcaagccaat tctacatctt tcgatataat ttgtaaacat
    13681 atttttactt tatttcaatt tttagtatat ttatttgtga aaactaaact ataattgttg
    13741 aacatttaaa tttatacctc ttttatccaa ttaattaata tactactgca tttttggttt
    13801 tgcaaatctg taaaatatcg gattataaat agcgaaaaag ctctttacac attgggtttg
    13861 ggggggcggg ccgatgcgca aaaacagcag atttttctcg tagaaaaaca ggccaaccag
    13921 aagtttctgg ctgacctgat cctgtgaaaa aaaagcaccg tctctcttac gagaaacggc
    13981 gctttttatg tagggctgta caaaaagcta ttccttgtct tcaacttcca caaccgaatg
    14041 gctgatggaa ccccggtcaa aggtcagctt ggtcacatcg tttacccgca ggactacgat
    14101 gtcatcggaa atttccatga tcgtcccgtg aaggccccca atggtcacta ccttatcgcc
    14161 ttttttcaga gctttcaaca ttgcgttgcg tgtcttggtc ttcttctgct gcggacggat
    14221 aagcaggaaa tagaacacca caaacattag cacaaatggg cctacaagac ccagaatgct
    14281 tccgccccct gaggctgctg catattgaaa ctgtaacata attctccccc ccttcaaaag
    14341 acaatgaaac actgcccctt acctaaaaac cttttagatt atcatataat ccgtattgtg
    14401 caaaaaactc atcgcgaaaa tcaagcagcc gatcttccct gatggcttca cgcactttac
    14461 gcatcaattc cagcaggaag tataaattat ggtatgtcgt taaccgcagg ccgaaggttt
    14521 catcggcttt gatcagatgg cgcaaataag cacgggaata attccggcag gtatagcagc
    14581 cgcattccgg atcaagcggc ccgaaatcgc gtgcatactg cgcgttgcgg actacaagtc
    14641 ttccctgact ggtcatcgtt gtcccattgc gggcaatacg tgtaggcaga acacagtcga
    14701 acatgtctac tccacggatt gatccttcca gcagcgcatc gggtgaaccc acgcccatta
    14761 aataacgcgg tttcccttgc ggcagcagcg gaaccgtata atccagcact tcatacataa
    14821 gctgcttgga ctctccgacg ctgagtcccc caatagcata ccccgggaaa tccatggaag
    14881 tcaaatcagc cgcgctctgg cgccgcaaat cctcatgcat ccccccctga acgatagcga
    14941 acagcccctg gtcttcagga cgggcatggc ttttgagaca tctttcggcc cagcgtgtag
    15001 tgcgttccag cgattttttg acgtaatcat attctgccgg atacggcggg cattcatcaa
    15061 aagccatcat gatatcagaa cctagcgcat tctggacctc catcgctact tcgggcgaga
    15121 gaaacttctt atccccattc aggtgggaac ggaagtgcac gccttcttca gtgattttgc
    15181 gcatgtcact cagcgagaaa acctgaaagc cgccgctgtc agttaagata ggccggtccc
    15241 agttcatgaa tttgtgcagg cctccggctt cgcggataat atcatgaccc ggacggagaa
    15301 acagatggta cgtattgctt aaaataatat gcgcatccat ctgtttcaat tcttcaggac
    15361 tcattgtttt gacggtggca agtgtaccta caggcataaa agcgggcgtc tcaattatgc
    15421 catgcggggt gtgcacccgc ccgagccggg caccggattg cttgcaggtc ttgatgtgtt
    15481 cataagttat tgctgccata tgtttaaccc ttcctcttgc ttaataaata aacattgcat
    15541 cgccgaagct gaaaaagcgg tattgctgct gaatcgcggc ttcataggcg gccagaatat
    15601 tctcccgtcc ggccaaggcg ctcaccagca tcaccaatgt ggatttgggc agatgaaaat
    15661 tggtaatcag tgcgtttaca acggtgaatt tgtagcccgg atagataaaa atatccgtcc
    15721 agccgctgca ttcttgaatc ggaccgcctt cggcctgtct gccaaccgtt tccagtgtcc
    15781 ggcaggacgt tgtgcccaca gctatgatcc ttccgccccg ggctctggca gcattgagca
    15841 catccgctgt ctcctgggac aagacgaaat actcggcatg cattacatgc tcttctacct
    15901 tctctaccga catgggacgg aaggttccaa gtccgacatg aagcgtaata taggcaatcg
    15961 tcacaccttt agccttgatt tgctccagca gctcacgggt gaaatgcagg cctgcggtcg
    16021 gcgcagccgc cgaaccctca tgcttggcat acaccgtctg gtaacgctcg cggtcatcca
    16081 gggtctcctt gatatacggc ggaagcggca tgcttcccag cctgtccaga atttcctgga
    16141 atattcctgt atagatgaag cggagtgtcc gtccacccat gtcagcctca tcttcaataa
    16201 ttgcccgaag ttcctcgctg aagatgatca cagctccggt cttcaacttc ttgccgggct
    16261 tcaccagcgc ttcccagcgg tcttcgccca gattcttcag cagcaggacc tccgccttcg
    16321 caccggtgtc ttccttaacg ccgaagagcc gggcgggaat cacccgtgta tcattcagaa
    16381 ccagcgtatc tcccggctga aattgttcca gtatatccgt aaaatgccga tgctccagtt
    16441 ggccattctc cttgttcacg agcagcagcc gcgatgcact gcggtcggac agcggagtct
    16501 gggcgatgag ctcctccggc aaatggaagt cataatcgtc aacattcatg gtcagtcttc
    16561 attccttaac tatagtaacg ttattaaaat agtgttgcaa tatttgctta taatcatacc
    16621 ctttgtccgc catgcccttc acaccccatt gggacatgcc aagcccatgg ccgttccccc
    16681 agccgataaa ataaaatccg gggctggtcg tgactactct ggacgaagca tctgcgccca
    16741 taactaccgt accgctgcca ttcgcagtca ctttgcccga cgcagagagt actccggcgc
    16801 tctgggagct gtcaaccgtt gacgttgagc cgtcagcgcc taatacagta taactgccgg
    16861 caggtacaat atcaaacaaa gtactcggca atccgccgaa cgccgaacgg aacagatcgg
    16921 gatatttcac ctgcagaatc tccccgttgg cttttacttg tgtgactctt cccgaaggac
    16981 cgcgctgcga aacctgcaga ctgctgatgg aagagggcag tgaactgctg accttgcccg
    17041 acaggctttt tagcagctcc gcagaagtgt agggcccctt aacccagctg tagcttccgt
    17101 tctcatagaa ctgatccaga actacggcat tttcgccggg gttcagcttg ccgagcggac
    17161 ttgcaccgct ctcaacgaca ggcagcgggc ggatattcac atctttggtg ctcgcagtag
    17221 ctataaccag gcctgacgct gtcttgctgc cggttaattg gatattgtcc tcccgggcgt
    17281 aacccgagac gccgctgtcc agcagcaagt aataccattt cttcgatgcc gctgctgcag
    17341 cggagtcttc ggcactggca acactgacaa aggtggtgcc tccgttgccc catacctcgg
    17401 aagggtcggc ggtcacaccg ccgctattgg aggaaaatac ggcctccaca atcttgctgc
    17461 cgctcatcag cacctccccg gcagtagcat ctactgactt agtaattacc ggtgcttcag
    17521 caccaatgcc gttgtatacc tggctgaggg tggtatccac cacattcgcc acgtcaaagc
    17581 ggttgccctg cgacagcgca tagctccgtg cagccacggc ctgggcttta agcgcttctt
    17641 cgggccagcc cgatgaaact tctccgccga ctaccgcata caaatactgc tccagcggaa
    17701 cttcgttaat gacagcaagg gatcccgcaa gcccgctgag ttccagattc ccgcggtaaa
    17761 tacgtttgga acgctcggcg atttgaatcc ctgcggaatt gcccgaggcc atgaacttgg
    17821 ctcctgtgcc ggatacctga tagtggaatg cctggctctc gctgctccag tccaatcctg
    17881 catccgtgcg gatcatcatc cccggtgtgg tcgttgcccc ggcggatacg gcaagctgcg
    17941 gaagcgcagc tgtaactgca gtccgcagcg cggccagatc actgtcgctt gccgcttctc
    18001 cgacccatac ttctacttgc gcgctgccgg ctggtccgct tgtcagcgtc ttccaggcat
    18061 caaagccggc cgcagtaatc gtactgacca cagcatccgc ttcttcaaga gtagcaaagg
    18121 agccagcaga cagatgtttg cttccagcca aggcaggagt ctgcccttca gcaagggaca
    18181 ggcctgcttt gcttacccgg ttcagccctt ccctggcagc actttcactg gtgtacgggc
    18241 cggtgtacag ctggtagact gtcgcaccat tgcgtgaagc cacaaataac atcggcttat
    18301 cagaggtcga ttgaagcttc ttggcagctt ctgcagctgc ctgccatgta ggactgtcca
    18361 tcaccttgac cttgtatccg tcgagactga tgcggattct gttattggcc ggaatgggca
    18421 gcagcggcgt actgccggac atcaggctaa agcccacagt cgagctcagc gtcacgaaag
    18481 ggacggtaga tttgtatttg ctgccaatat cggcatatag cgcaacccgg atagttgcgt
    18541 tcggatcggc atggctgtca gcggcaggaa gcaggaggcc gcctgtcatc agggcacctg
    18601 caagcaggct cattcctgtc tttttccact tggcaagatt catcttgatg cctcctataa
    18661 tagaaatgat agcaaaatcc aggattattg cggctgcgga ggaagcggaa ggcccaaatg
    18721 ctgataagcg gcaggagtca caactctccc ccgcggcgtc cgctgcagaa atccaatctg
    18781 cagcaggtaa ggctcatata catcctcaat ggtctggctc tcttctccga tcgtcgcagc
    18841 tatggtatcc agtcccacag gtccgccgcg gaaggaactg atcatggaat gaagcatctt
    18901 gtgatcgatg ctgtccagtc cgcgcgggtc cacctggagc atcttcagcg attctccggc
    18961 aatctccggc gtaatgatcc cgtcgccgcg cacctgcgcg aaatcgcgga cccgcttcag
    19021 caggcggttg gcaatccgcg gagttccccg ggaccgcaaa gcgatctctt ctgcagcatc
    19081 gcccagaatc tcaatgccga gcagttcggc attgcgggaa acaatgaagc tcagctcgtc
    19141 aatcgtataa tactccagcc ggctgaccac accgaagcgg tcacgcagcg gcgcagacag
    19201 cagcccggcg cgggtagtgg cgccgattag cgtaaagggc ggcaggtcca gtcgtaccga
    19261 gcgggcgctc ggacccttgc cgatcataat atccagcgcg aaatcctcca tcgccggata
    19321 catcacctct tccaccgtcc ggtgcagccg gtggatctca tcaatgaaca ggacatcgcc
    19381 ctgctgaaga ttggtcagca gcgcggccag atcgccgggc cgctcaatgg caggcccgga
    19441 tgttgtcctg aggttcacac caagctcatt ggcgataata ttcgcgagtg tcgttttacc
    19501 cagcccggga ggcccgtaca gcagcacatg gtccagcgct tcgctgcgca ttttggcagc
    19561 ttctatataa attttcagat tctctttaac ctggttctgt ccgatatact ctcccagata
    19621 gcgggggcgc agacttaatt ccaccgcctg ctcgtccatc atcaggttag ccgatataat
    19681 ccggtcatcc atttatccat cactccgttc tgtcaagcag cctatttggc tatatacagc
    19741 agccccagcg ccttcttcat cagcacatca acgggacctg tatcggcgcc ttccttcttc
    19801 atggtcagcc atacccggtc cagctcggct tcggtatatc caagagccct caggccgtcc
    19861 cgcgcttcct cccaaggcat tgcttcttcg gccgcctggg cttctgccgc tacagcaaac
    19921 aatcctgtct gcatggatac cgcgctcaac ccgtccagct tgtcccgcag atccagaatc
    19981 atccgctggg cggtcttctt gccgatcccc gggagcttgg tcaggaaggt gatattctcc
    20041 tggtaaatcg cggagatcag ctgatccggt gttccgccgg tcagaatccc cagggctacg
    20101 cgcgggccaa tgccggatac ctcaatcagc ttgcggaaca gcttctgctc ttctcttgtc
    20161 gggaacccga agagcagggt agcatcctcg cgtgtctggt aatgaatgta gaccgtcacc
    20221 ggcccctcca acttggcaaa agcatacgga ttcgggcaga acacccggta tcctatgccc
    20281 tggacatcca ccaccacata ttccggctcc aaatggacaa ccggacctct taagtaatct
    20341 atcattttcg caatacctca tttaatttgg aattaagact caccgaatgg gcgtggcata
    20401 ccgccaccgc cagcgcatcc gccacatcat caggcttcgg tacagccgcc agcttcagca
    20461 gcagcttgac catttcctgc acctgcttct tctcggcctt gccatagccc accacagcct
    20521 gcttcaccat catcggagta tactccgcga caggaagccc gcgctggaca gcggccagga
    20581 tcagcacacc tcttgcttgc gccaccggca gagccgtcgt cacattgcgg ctgaaaaaca
    20641 gcttctccac cgcgaccgca tcaggctggt atttatcaat aagctgcacc ataccctcgt
    20701 atacatgcag cagacgttcc tcctccggcg tatgcgcctc cgtctggatg cacccgtact
    20761 gcaccggcgt taatttgtta cctgccttat ctacgaagcc gaagccgaca atcgccagcc
    20821 ccgggtcaat gcccaggatg cgcaaatcca atctctcctc ttaagcaggc cgtctattcc
    20881 tgcggtttca tccatttcgt tgccttgaag cgaacatatg tattccttct aatcattata
    20941 gcaaaaaacc ttcttccggg agaataaaag tttgccggga ttcctgccgg cttccgcaag
    21001 cgaaaaaaag agggagtgtc cgggcactcc ctgcagcaaa aaaaagccgc cccatgcata
    21061 gaggcggcct tcttacccta tagttattct tcgctttgca tcacctgttc cgatgagtcc
    21121 cgcgcataat cgctgaaggt ggacagcacg ctgttgtact cttctacatc ctgcacacgg
    21181 atgccttcat gcagctgctc taagatatca tccggcagcg aagacttcat cgagcccatg
    21241 tccatctgaa aaaaagtttt cagcaccttc tcctccgcag gaggaccttt gaacagggtc
    21301 agattcccgt gctcgtctac gccgataaaa gcgtctttct taatctgagg cgacaaatcg
    21361 ttgaccatat gctccaacca cagatccccg tccgcgctga tccagccgtt ccagtccgga
    21421 tgtgcagc
//
