LOCUS       NZ_KN150952            21050 bp    DNA     linear   CON 15-JAN-2024
DEFINITION  Burkholderia pseudomallei strain BEC scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KN150952
VERSION     NZ_KN150952.1
KEYWORDS    WGS; RefSeq.
SOURCE      Burkholderia pseudomallei
  ORGANISM  Burkholderia pseudomallei
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3317933)
  AUTHORS   Daligault,H.E., Davenport,K.W., Minogue,T.D., Bishop-Lilly,K.A.,
            Broomall,S.M., Bruce,D.C., Chain,P.S., Coyne,S.R., Frey,K.G.,
            Gibbons,H.S., Jaissle,J., Koroleva,G.I., Ladner,J.T., Lo,C.C.,
            Munk,C., Palacios,G.F., Redden,C.L., Rosenzweig,C.N., Scholz,M.B.
            and Johnson,S.L.
  TITLE     Whole-genome assemblies of 56 burkholderia species
  JOURNAL   Genome Announc 2 (6), e01106-14 (2014)
   PUBMED   25414490
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3317933)
  AUTHORS   Bishop-Lilly,K.A., Broomall,S.M., Chain,P.S., Chertkov,O.,
            Coyne,S.R., Daligault,H.E., Davenport,K.W., Erkkila,T., Frey,K.G.,
            Gibbons,H.S., Gu,W., Jaissle,J., Johnson,S.L., Koroleva,G.I.,
            Ladner,J.T., Lo,C.-C., Minogue,T.D., Munk,C., Palacios,G.F.,
            Redden,C.L., Rosenzweig,C.N., Scholz,M.B., Teshima,H. and Xu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; AllPaths v.
            39750; phredPhrap v. SPS - 4.24
            Assembly Name                     :: BEC
            Genome Coverage                   :: 279.0x
            Sequencing Technology             :: 454; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/15/2024 02:29:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,952
            CDSs (total)                      :: 6,888
            Genes (coding)                    :: 6,565
            CDSs (with protein)               :: 6,565
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 131 of 323
            Pseudo Genes (incomplete)         :: 228 of 323
            Pseudo Genes (internal stop)      :: 25 of 323
            Pseudo Genes (multiple problems)  :: 51 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:39:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1331852
            Orig. end                         :: 1352902
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KN150952.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21050
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21050
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21050
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11050](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11050)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    201..215
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    1043..1052
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     assembly_gap    1144..1243
                     /estimated_length=unknown
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1244..3285)
                     /locus_tag="DO72_RS05605"
     CDS             complement(<1244..3285)
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529786.1"
                     /locus_tag="DO72_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="WP_038792892.1"
                     /transl_table=11
                     /translation="MTDHTPHSSPPASPTPPQGPAPKRRRYFRTLAGLVLGAAIAGGAV
                     GTWTLHRIWTALPSVEPLAVYRPALPLRIFSREGELLAEYGVERREFVPLDRIPPLVRH
                     ALLAAEDAQFYTHGAVDIGGLARATVANVVTGQPGQGGSTITMQVARNFFLTREKVLSR
                     KLAEILMSYKLERAYSKDKLLELYMNEIYLGERAYGFAAAASVYFGKPLDALTPGEAAV
                     LAGLPKAPSAFNPVVNPARATMRRNYVLGRMRALGYLDEAAYRQAADAPIALATTPPPG
                     ILAAPYVAERARRMMVERFHDDAYTLGLDVTTTIAMREQRAADAALARGLAQVGRRDAK
                     DALEGALVSIDAATGDILALVGGADFSHNVFDHALQAYRQPGSSFKPFVYSAALEKGMF
                     PGVLIDDTQRTLSRDETGANPWRPRNFGNHYEGFIPVRRGLMRSKNLVAVSLMQVARPD
                     FVQQHAARFGFEPLRNPASLPLALGAGSATPLEVASAYGVFANGGVRMEPRLIESVRQR
                     HGGALFDAQPAPGVRVISARNAFVMDSMLRDVVAHGTARRAVALKRADAAGKTGTSNGS
                     KDVWFAGYSSGVVSVVWMGYDAPRSLGRATGSSAALPVWVDYMKTAVDGRGAIERTPPA
                     DVALVDGDFVYAEYANGDKCAPSLPPFVRSPFACGAARGAPADGGA"
     gene            3462..4439
                     /locus_tag="DO72_RS05610"
                     /old_locus_tag="DO72_6235"
     CDS             3462..4439
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004196050.1"
                     /locus_tag="DO72_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6235"
                     /product="HTH-type transcriptional regulator ArgP"
                     /protein_id="WP_004523490.1"
                     /transl_table=11
                     /translation="MTIDPKQAAALVAVADTGSFEQAAARLHVTASAVTQRVRALEASL
                     GAPLLLRTRPCRPTAAGQRVLQHLRRMALLQVDLQAELEAERGSTIAVAIALNSDSLGS
                     WFLPALTSVLAGERMLFELIVEDQDHTFALLESGMAIGCVTTQSKPMRGCFATPLGTMR
                     YRLIAAEEFAARWFAQGLTRESAREAPVVAHGRRDTLQSSFLRDKLGLPDGAFPCHYVP
                     GTHAHFAAVRHGLGYAMVPELLLGTTPLAEQRLVDLAPAHSTDVSLYWHAWTVQSPKME
                     SLSSRVVEAAQQLLAPPPRGAAAAGGRAAAAPAPVKRANARNTR"
     gene            complement(4408..5421)
                     /gene="ltaE"
                     /locus_tag="DO72_RS05615"
                     /old_locus_tag="DO72_6236"
     CDS             complement(4408..5421)
                     /EC_number="4.1.2.48"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Beta_elim_lyase (2-283). E-value:
                     1.8e-90. Score: 295.0. Matches aSDomain:
                     nrpspksdomains_DO72_RS05615_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene="ltaE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012339268.1"
                     /locus_tag="DO72_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6236"
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="WP_004529784.1"
                     /transl_table=11
                     /translation="MIDLRSDTVTRPSAPMLAAMTAAEVGDDVWGDDPTVARLQAVVAE
                     RAGKEAALFFPSGTQSNLAALMSHCERGDEYIVGQAAHTYKYEGGGAAVLGSIQPQPIE
                     NAADGTLPLEKIAAAIKPIDDHFARSRLFTLENTIGGKVLPAGYVDEAVALARSRGLAA
                     HLDGARVCNAAVASGRAIAELCAPFDSVSICFSKGLGAPVGSVLVGSGALIERAHRWRK
                     VLGGGMRQAGVLAAACLYALEHNVERLADDHANAERLAQGLARIEPVKVLSQATNMVFA
                     QFPEADCAPLEAWLKERGILTQMLYASRFVTHCDVSRDDIDTAVAAISAYFARSRA"
     aSDomain        complement(4573..5415)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS05615_Beta_elim_lyase.1"
                     /evalue="1.80E-90"
                     /label="DO72_RS05615_Beta_elim_lyase.1"
                     /locus_tag="DO72_RS05615"
                     /protein_end="283"
                     /protein_start="2"
                     /score="295.0"
                     /tool="antismash"
                     /translation="DLRSDTVTRPSAPMLAAMTAAEVGDDVWGDDPTVARLQAVVAERA
                     GKEAALFFPSGTQSNLAALMSHCERGDEYIVGQAAHTYKYEGGGAAVLGSIQPQPIENA
                     ADGTLPLEKIAAAIKPIDDHFARSRLFTLENTIGGKVLPAGYVDEAVALARSRGLAAHL
                     DGARVCNAAVASGRAIAELCAPFDSVSICFSKGLGAPVGSVLVGSGALIERAHRWRKVL
                     GGGMRQAGVLAAACLYALEHNVERLADDHANAERLAQGLARIEPVKVLSQATNMVFAQF
                     "
     misc_feature    complement(5410..5412)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(5826..5839)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            6017..7429
                     /locus_tag="DO72_RS05620"
                     /old_locus_tag="DO72_6234"
     CDS             6017..7429
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0070069 - cytochrome complex [Evidence
                     IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894127.1"
                     /locus_tag="DO72_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6234"
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="WP_004557697.1"
                     /transl_table=11
                     /translation="METAFSALDLARVQFAFTVSFHIVFPALSIGLASFIAVLEYRWLK
                     TGKAYYKSLCLFWSKIFAVAFGMGVVSGVVMAYQFGTNWSGFSSFAGSVTGPLLMYEVM
                     TAFFLEAGFLGIMLFGWNRVSPRAHFGATLMVAIGTLISTFWILASNSWMQTPQGFEIV
                     DGQVVPTDWFAIIFNPSFPYRLAHMAIAAFVVAALVVAATAAWHLLKGRRDKAVKKMFS
                     MSLWLLLVLAPLQAVIGDQHGINTLRHQPAKLAAIEGLWETEPGGTALNLFGIPDMKAE
                     TTRYAVSIPHLGSLILTHSWDGEIRGLKSFPPQDRPNSTVVFWSFRIMVGLGLAMIGLA
                     ALAWLLRRRGRLYEAKWFHRFALAMGPTGFVSLLAGWVTTEVGRQPWVVYGVMRTSHAV
                     SPLSTQQVSVSLMTFVVVYFLVFGTGVYYMLKLMRKGPALPGDTPDDAHDARPERTARR
                     PLSAANQLIDAA"
     misc_feature    complement(7460..7474)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            7465..8472
                     /gene="cydB"
                     /locus_tag="DO72_RS05625"
                     /old_locus_tag="DO72_6233"
     CDS             7465..8472
                     /EC_number="7.1.1.-"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene="cydB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011548943.1"
                     /locus_tag="DO72_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6233"
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="WP_024428776.1"
                     /transl_table=11
                     /translation="MDVTVIWAAIIALGLFMYVVLDGFDLGIGIVFPFFPAEQERDLMM
                     NTVAPVWDGNETWLVLGGAGLFAVFPIVYSTVLSALYLPLVFMLVCLIFRGVSFEIRAK
                     ARRTKHLWDLAFIGGSTGATFFQGVALGAFLQGIPVDGGRFAGDAFGWLTPFSLLTGLG
                     LIATYALLGCCWLVAKTEGDLQRRLHRVVWPLTVVLLGFIAVVSLWTPLQDTNIAQRWF
                     ATGLFWRLLPVPFLVAGCAALMRRAVRERHDTTPFALALALVFLGYVGLLVSLWPYAIP
                     QSVTLWEAAAPRSSQTFTLIGAAVIIPVILAYTTMGYWVFRGKVRHEDQHYYHH"
     gene            8444..8614
                     /locus_tag="DO72_RS35390"
                     /old_locus_tag="DO72_6232"
     CDS             8444..8614
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011401528.1"
                     /locus_tag="DO72_RS35390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6232"
                     /product="hypothetical protein"
                     /protein_id="WP_004188088.1"
                     /transl_table=11
                     /translation="MKTSITTTTEPRAVARGARLPGWMWFALLWMGGVAGAVTLGYAFK
                     LFMYATLFAVK"
     gene            complement(8955..9149)
                     /locus_tag="DO72_RS05630"
                     /old_locus_tag="DO72_6231"
     CDS             complement(8955..9149)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007586056.1"
                     /locus_tag="DO72_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6231"
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="WP_004523495.1"
                     /transl_table=11
                     /translation="MRLLLALLLPWLQFFTIGRPFAGIICLILQITLIGWLPAAIWSVY
                     ALSQYKTDRKIEEALGRRS"
     gene            <9383..9975
                     /locus_tag="DO72_RS05635"
                     /old_locus_tag="DO72_6230"
                     /pseudo=""
     CDS             <9383..9975
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894133.1"
                     /locus_tag="DO72_RS05635"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DO72_6230"
                     /product="LysR substrate-binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VRGHRERFPRVELELNSNEGVIDLLERRTDVAIRIGRLKDSTLHS
                     RLTGNSRLRILASPAYLDAQGRPRKAGDLGKHALLGFNRPESLNVWPTSARTASLAGSR
                     RPCGRRAARRSDSSRSTARASSAGRIS"
     gene            complement(10001..11050)
                     /locus_tag="DO72_RS05645"
                     /old_locus_tag="DO72_6228"
     CDS             complement(10001..11050)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011852603.1"
                     /locus_tag="DO72_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6228"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_011832071.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.1e-44,
                     bitscore: 150.3, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 3.4e-15, bitscore:
                     53.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNSTRAFLLGPLLKGVSRSFYLTLRVLPQGMRDPIGLAYLLARA
                     ADTIADTSLIPPAQRLELLLSLRAQINGAPDPHALARIAGEVAGQQAQTDEKTLLESLG
                     PALAVLSQLSAPDRAAVRGVVTTLTEGMEFDLRTFPDESSGRIVALREWPALDRYTYLV
                     AGCVGEFWTKMTCAHLPGLLTEREDTMSERGIRFGKALQMTNVLRDCGRDLRIGRCYLP
                     QAMLDEYGLRAEDLLGPDASLRVRPLMHALVRTTLAHFRAGIDYTFAIPRRAPRLRLAC
                     FWPIAIGLRTLALLASNDAWLDPARASKVRRGDVYRILAYSLPLAMSNGALRAWLDRLI
                     ADVEARLIA"
     misc_feature    11056..11070
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            11231..11524
                     /locus_tag="DO72_RS05650"
                     /old_locus_tag="DO72_6227"
     CDS             11231..11524
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006029069.1"
                     /locus_tag="DO72_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6227"
                     /product="hypothetical protein"
                     /protein_id="WP_004188119.1"
                     /transl_table=11
                     /translation="MTAMAMKKTDLEKNKALKLTHAMKQTTSARFGKGAEDAAADRRER
                     RRLEQAQGLVPFACKLNIELVARLNERAAAHPDGMTGLLTELLQRGLDETAK"
     gene            11652..12041
                     /locus_tag="DO72_RS05655"
                     /old_locus_tag="DO72_6226"
     CDS             11652..12041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004523497.1"
                     /locus_tag="DO72_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6226"
                     /product="VOC family protein"
                     /protein_id="WP_004551257.1"
                     /transl_table=11
                     /translation="MNPPVLRVARPTNDIDTLVRFYTKALGFDVVARFENHEGFDGAIV
                     GRAGYPWQIEFTHQHGVTVARAPTAEHLLVFYLPDRGAWTEAVARMRAYGATPCRSENP
                     YWDREGVTFEDPDGYRIVLQNAQPA"
     gene            12206..12670
                     /locus_tag="DO72_RS41630"
     CDS             12206..12670
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DO72_RS41630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_195761024.1"
                     /transl_table=11
                     /translation="MSGVAALVERAARSRRAPLRRDAAHARSSAALPRCRAVAPTNEIP
                     ATARHPRDTCIRARRRIPLERTPGGSPRSATPLSPSPRTSPRTAARPPAETHSHNFAAP
                     LVAQAPRAAARADRQTKAARHDALAIPVQIAAPGVGHSRSNDEVNDETQQ"
     misc_feature    12587..12589
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12654..14315
                     /locus_tag="DO72_RS05665"
                     /old_locus_tag="DO72_6225"
     CDS             12654..14315
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009967568.1"
                     /locus_tag="DO72_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6225"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_004523498.1"
                     /transl_table=11
                     /translation="MKRNSKQFEIGAWLGACALAFAGAASAAAVQDRDHDSRPVDAKRV
                     LLASIDGLHEQDLARCIGANTCPNLALLAKSGVTYTNARTPGLSDSFPGLAALVTGGSP
                     KSAGLFYDVSYDRTLYAPSDATCSGKQGWNVVFDETTGIDAMNGGALTHLDGGGAFNPQ
                     AIPHARVNGQCVSVYPHDYVKTNTVFEVVKEHLRGSHTAWADKHAWGYDWVNGPSGKGV
                     DDLARTEINSIDPATGTPYTDIYTHTEKFDDYHVQAIVNQIDGKNSTGTAAAPVPTLFG
                     TNFQTLSVAQKATVASGGGYLDASFTPGPEVANAIAYVDGALGRIVAELRQRGLYDSTV
                     VIVTAKHGQSPTDHTKLVKHGDTLTALLEANGFVDPNGNFGQNNTASGNPNDGTGLVGT
                     GFVQTDDVGLVWLRDPRQLSAAVATLKANLGCNAPGICADGPQAYILYGPSVAERFGNP
                     ALGRTPDIVVQPNPGVIYTSSKKKDEEHGGNAPDDSHLGLLVSYAGLRQGRTIDAPVLT
                     TQVAPTILRSLGLEPRLLHAVALEGTRVLPGLGLER"
     misc_feature    14641..14657
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            14683..14904
                     /locus_tag="DO72_RS05670"
                     /old_locus_tag="DO72_6224"
     CDS             14683..14904
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529774.1"
                     /locus_tag="DO72_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6224"
                     /product="hypothetical protein"
                     /protein_id="WP_004529774.1"
                     /transl_table=11
                     /translation="MATLEAFRCVLDDARTPEIIRHHIIDALQYALRNYGQVFTAKEVE
                     WLAAWDDPRIPLAARKELDRREPAAAAR"
     CDS             complement(15030..>16269)
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187804.1"
                     /locus_tag="DO72_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_6223"
                     /product="DUF748 domain-containing protein"
                     /protein_id="WP_009932641.1"
                     /transl_table=11
                     /translation="SPASGAAVVRAAAPPQHPVRLHFGQLLLQRGRVTYTDNFIKPNYT
                     ANLVAINGTIGAFGTDSTAPAPVDVGANLAGNGPITIKGTVNPLIEKPSLDLTATAHDI
                     ELTNLTPYSAKYAGYPITKGKLNVDLHYKLDNDLLSANNHIFIDQLTFGEHVENDTATK
                     LPVRLAIALLKNSRGEIDVNVPVSGSLSNPEFSIGGLIWRAVLNLIAKAVTSPFTLLAH
                     AFGGDGEALGYVEFEPGRSKLSDASQKKLDTISKMLAEKPSIRLDLIGRVDPDKDLPGL
                     RDAYVERLVRQQKLKDVVGQGESVDPMTVKVDPAEYTKYLTKAYKAADFKKPRNMIGFT
                     KTLPDDDMRKALADHASVDDSSLRALAQARAQAVRQYLEGKVDSSRMFIVAPKLDAKGI
                     EDKGATTRVDFGLK"
     gene            complement(15030..>16273)
                     /locus_tag="DO72_RS05675"
                     /old_locus_tag="DO72_6223"
     assembly_gap    16274..16373
                     /estimated_length=unknown
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            16577..16837
                     /locus_tag="DO72_RS05680"
                     /old_locus_tag="DO72_3497"
     CDS             16577..16837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004188746.1"
                     /locus_tag="DO72_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_3497"
                     /product="DUF2866 domain-containing protein"
                     /protein_id="WP_004188746.1"
                     /transl_table=11
                     /translation="MVEDTVFSGLRTLLTHEHAFPVQSCRVSIEMQRPWGRPYRLVEWT
                     MHLDAPARRRIVPAESTEAEIAEAVASHVPGRLYEGGAALY"
     misc_feature    complement(16586..16597)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.54"
                     /tool="antismash"
     misc_feature    16613..16615
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16624..16637
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.22"
                     /tool="antismash"
     misc_feature    complement(17032..17047)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.13"
                     /tool="antismash"
     misc_feature    17315..17328
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.07"
                     /tool="antismash"
     gene            17320..17703
                     /locus_tag="DO72_RS05685"
                     /old_locus_tag="DO72_3496"
     CDS             17320..17703
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004553126.1"
                     /locus_tag="DO72_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_3496"
                     /product="DUF6232 family protein"
                     /protein_id="WP_004551270.1"
                     /transl_table=11
                     /translation="MENAFNERGVMVTRNGLSAAGQIFALREIRGVEVRTVRKNKLVPC
                     AISLTGAAAAIAGGALGSSALLVAGVMLVVVGYLAWTTQDVTHRLIVDMPDGKREAIMS
                     VDREFVERVAHAVDAARAAGAST"
     misc_feature    17323..17334
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.66"
                     /tool="antismash"
     gene            17700..18173
                     /gene="aac(6')-III"
                     /locus_tag="DO72_RS05690"
                     /old_locus_tag="DO72_3495"
     CDS             17700..18173
                     /EC_number="2.3.1.82"
                     /codon_start=1
                     /gene="aac_6__-III"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004548791.1"
                     /locus_tag="DO72_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_3495"
                     /product="tobramycin N-acetyltransferase AAC(6')-III"
                     /protein_id="WP_004187817.1"
                     /transl_table=11
                     /translation="MTHPAALFKIRAAQASDAAAWRQLRRALWPHADDIEHARDIARQL
                     DAPARHACFIASPPGILAPVGFAEVAVRHDDVNGCGASPVLFLEGVFVEPAARRRGVAR
                     ALCAAAAAWGTARGCAAFASDAPLENAASHALHRALGFDETERVVFFRKPLAR"
     gene            complement(18207..18866)
                     /gene="dhaL"
                     /locus_tag="DO72_RS05695"
                     /old_locus_tag="DO72_3494"
     CDS             complement(18207..18866)
                     /GO_function="GO:0004371 - glycerone kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006029038.1"
                     /locus_tag="DO72_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_3494"
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="WP_004529804.1"
                     /transl_table=11
                     /translation="MNTAAIQCLPLADAGFVVRELVDVIRRNRDHLSEIDAAIGDGDHG
                     INMSKGFGQCGARLDARGATSLPDALDVLSTALMDGIGGSMGPLYGSFFMDFAAPLKGR
                     DTLDAALFGEALAAGFAGVQAISDAKIGDKTLIDTLAPAAAAFHEALRAGDDFRHALAA
                     MSAAAERGKESTRWLQARVGRASRLGERSVGTLDAGAASCCLILCSLASSIGARLN"
     gene            complement(18863..19867)
                     /locus_tag="DO72_RS05700"
                     /old_locus_tag="DO72_3493"
     CDS             complement(18863..19867)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0004371 - glycerone kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603786.1"
                     /locus_tag="DO72_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_3493"
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="WP_004531484.1"
                     /transl_table=11
                     /translation="MNRVINHPDYVVEDMLRGIVAAHPALALDADNPRVIGVAHPVPGK
                     VGVVTGGGSGHEPAFVGYTGPGLVDAVAIGEIFSSPTAKSFLDAFRRADRGAGVACLYG
                     NYAGDNMNVKMAIKMAAAQGIDVKTVVANDDVASAPREERAKRRGVAGEILMWKAGGAR
                     AAAGGDLDAVIASAKKAIDNTRSVGIGLSACTIPANGKANFHIADGEMEVGIGHHGEHG
                     VRVMRTVSAKDMAAMMLDIVLPDFPLERGEEVAVLVSGLGATPLMEQYILYAEVSQRLA
                     AAGLKIGFRLVGNLFTSLEMMGVTLTVTRLDDELKQLFAAPCSSIGLTVGERA"
     gene            complement(19872..21008)
                     /locus_tag="DO72_RS05705"
                     /old_locus_tag="DO72_3492"
     CDS             complement(19872..21008)
                     /NRPS_PKS="Domain: PKS_ER (151-374). E-value: 2.8e-08.
                     Score: 25.2. Matches aSDomain:
                     nrpspksdomains_DO72_RS05705_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187324.1"
                     /locus_tag="DO72_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_3492"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_004523470.1"
                     /sec_met_domain="ADH_N (E-value: 1.4e-24, bitscore: 83.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.8e-20, bitscore:
                     70.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQTAEAPPQRAAERGETPALPATMRAVVCHGPRDYRLEQVPVPK
                     PGPDEILTQVERVGICMGDIKTFRGAPSFWGDAVQPRYVKPPMIPGHEFVCRVVALGPG
                     AERRGVKAGDRVISEQIVPCWSCRFCGHGQYWMCQKHDLYGFQNNVHGAMAEYMIFTKE
                     AIVHRVPDSIPTDEAILIEPLSCSLHAADRANVGFDDVVVVAGAGTLGLGIIGAVRLRH
                     PKQLIVLDMKPERAALARRMGADDVWNPAEENVIEKIRAITGGYGCDIYIEATGHHRAV
                     GQGLAMLRKLGRFVEFSVFNDEASVDWSIIGDRKELDVLGSHLGPYMYPRAIEFIASRR
                     IDVRGIVTHTFPLSRFADAFAVMERGEQSLKVVLDPRG"
     aSDomain        complement(19887..20555)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS05705_PKS_ER.1"
                     /evalue="2.80E-08"
                     /label="DO72_RS05705_PKS_ER.1"
                     /locus_tag="DO72_RS05705"
                     /protein_end="374"
                     /protein_start="151"
                     /score="25.2"
                     /tool="antismash"
                     /translation="GAMAEYMIFTKEAIVHRVPDSIPTDEAILIEPLSCSLHAADRANV
                     GFDDVVVVAGAGTLGLGIIGAVRLRHPKQLIVLDMKPERAALARRMGADDVWNPAEENV
                     IEKIRAITGGYGCDIYIEATGHHRAVGQGLAMLRKLGRFVEFSVFNDEASVDWSIIGDR
                     KELDVLGSHLGPYMYPRAIEFIASRRIDVRGIVTHTFPLSRFADAFAVMERGEQSLKVV
                     L"
ORIGIN
        1 tgctcgacgg cgtgctcagc acgtcggtga acgcgaaggc ggactggtcg aagacgccgc
       61 tcgacgcgca ggtgagcgat agcgagctcg gcctgaaatc gctgaagatc gcgctgccga
      121 acgcgaaaac gccggccgtc gcgctgcccg acgcgcgcgt gaaggtgacg aagatcgatc
      181 tcgccgcgcg caccgccgag atcgcgagcg tcgatgcgac gggtctcgcg ctcgacgtcg
      241 cgcggctgca ggacggccgg atcgatctcg cgtcgctcgc gggcgacggc ggccgggcgg
      301 cgggcgcgaa gccggccgcg tcgaacgcgt cggccgcgcg cggcgcgcgg cccgccgcgc
      361 ccgcatggcg ctaccggatc gacgaactga acgtgaagga cgcgaaggcg aacttcaccg
      421 accgctcgac gccgcgcccc gtgaagctcg cgatcgcgcc gctcgcgctg aacgtccggc
      481 agatcagcga ggatctgtcc aagccgttgc ccgtcaggct gacggccacg ctcaaccgca
      541 agggctcgct cgagctgtcg ggcaacgtga cggcgcagcc gctgaaggtc ggcctgaagc
      601 tgaacggcaa ccggctcgac gcggccgcgt tcgagccgta tttcggcagc atgctgaacg
      661 cgacggtcgc gagcgcgctg ctgaacgcga agggcgagct gagcgtcgag caggcgaagc
      721 agtcgacgaa ggcgtcgtat cgcggcgacg cggcgctcgt cgatgtgcgg atgctcgaca
      781 aggcgacgtc cgatccgttc gccggctggc gctcgctcgc gctcgcgaac ctgaaggcga
      841 gctatgacga cgcgcgcggc accgacgtcg acgcgtcgcg cgtgacgttc tcgaatttct
      901 acggccgcgt gctgctcgac gcgcaaggca agctgaacct gcgcgaggtc gtcgccaagg
      961 agagcggccc cgcgcagtcg ctcacgcgcg atgcgagcgg caaggagccg atcccgctca
     1021 cgcctcaggc cgcgtcgcag gcgaaggcgg cgatcgcggc gtcggcggtc gagccggctt
     1081 cggcgcccgt gctcgcgtcg gcagcggcgg catcggcggc atcggcggcg gcagcggcgg
     1141 catnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngcgccgc cgtccgccgg
     1261 cgcaccgcgc gccgcgccgc acgcgaacgg gctgcgcacg aacggcggca gcgacggcgc
     1321 gcacttgtcg ccgttcgcgt attcggcata gacgaaatcg ccgtcgacga gcgcgacgtc
     1381 cgcgggcggc gtgcgctcga tcgcgccgcg gccgtcgacc gcggtcttca tgtagtcgac
     1441 ccacacgggc agcgcggccg acgagcccgt cgcgcggccg aggctgcgcg gcgcgtcgta
     1501 gcccatccag acgaccgata cgacgcccga cgagtagccg gcgaaccaca cgtccttcga
     1561 gccgttcgac gtgccggtct tgcccgccgc gtccgcgcgc ttgagcgcga ccgcgcggcg
     1621 cgcggtgccg tgcgcgacga cgtcgcgcag catgctgtcc atcacgaacg cgttgcgcgc
     1681 cgagatgacg cgcacgccgg gcgcgggctg cgcgtcgaac agcgcgccgc cgtgccgctg
     1741 ccgcaccgat tcgatgaggc gcggctccat gcgcacgccg ccgttggcga acacgccgta
     1801 ggcgctcgcc acctccagcg gcgtcgccga gcccgcgccg agcgcgagcg gcagcgacgc
     1861 ggggttgcgc agcggctcga agccgaagcg cgccgcgtgc tgctggacga aatccggccg
     1921 cgcgacctgc atcaggctca ccgcgacgag gttcttcgag cgcatcagcc cgcgccgcac
     1981 cggaatgaag ccttcgtagt ggttgccgaa attgcgcggc cgccacgggt tcgcgccggt
     2041 ttcgtcgcgc gacagcgtgc gctgcgtgtc gtcgatcagc acgccgggga acatcccttt
     2101 ctccagcgcg gccgaataga cgaacggctt gaagctcgaa cccggttgcc gatacgcctg
     2161 caacgcatga tcgaacacgt tgtgcgagaa gtccgcgccg ccgacgagcg cgagaatgtc
     2221 gcccgtcgcc gcgtcgatcg acacgagcgc gccttcgagc gcgtccttcg cgtcgcgccg
     2281 gccgacctgc gcgagcccgc gcgcgagcgc cgcgtcggcc gcgcgctgct cgcgcatcgc
     2341 gatcgtcgtc gtcacgtcca ggccgagcgt gtaggcgtcg tcatggaagc gctcgaccat
     2401 catccggcgc gcgcgctcgg cgacgtacgg cgcggcgagg atgccgggcg gcggcgtggt
     2461 cgcgagcgcg atcggcgcgt cggcggcctg ccggtacgcg gcctcgtcca gatacccgag
     2521 cgcgcgcatg cggccgagca cgtagttgcg gcgcatcgtc gcccgcgccg gattgacgac
     2581 cggattgaac gcggacggcg ccttcggcag gcccgcgagc accgccgcct cgccgggcgt
     2641 gagcgcatcg agcggcttgc cgaagtacac cgacgcggcc gccgcgaacc cgtacgcgcg
     2701 ctcgccgaga tagatctcgt tcatgtacag ctcgagcagc ttgtccttgc tgtacgcgcg
     2761 ttcgagcttg tacgacatca ggatctcggc gagcttgcgg ctcagcacct tctcgcgcgt
     2821 cagaaagaaa ttgcgcgcga cctgcatcgt gatcgtgctg ccgccctgcc cgggctggcc
     2881 ggtgacgacg ttcgccaccg tcgcgcgcgc gagcccgccg atgtcgaccg cgccgtgcgt
     2941 gtagaactgc gcatcctcgg ccgcgagcag cgcgtgccgc acgagcggcg ggatgcggtc
     3001 gagcggcacg aactcgcggc gctcgacgcc gtattcggcg agcagctcgc cttcgcgcga
     3061 aaagatccgc agcggcagcg ccggacgata gacggcgagc ggctcgacgg acggcagcgc
     3121 cgtccagatg cgatgcagcg tccacgtgcc gaccgcgccg cccgcgatcg ccgcgccgag
     3181 cacgaggccc gcgagcgtgc ggaaatagcg gcggcgcttc ggcgcgggcc cctgaggcgg
     3241 cgtcggcgag gcgggcggcg acgagtgcgg cgtgtgatcg gtcatgtcga aatccttcgt
     3301 tggcaaatgc ggcgtacgcc ctcgcgcgga tgttgcagtg cacgatgcgc acgcgcgcat
     3361 tgtccgggga ggatcccgat accgatacaa tatttagctc aagttgatta cgctaaattt
     3421 tatttaggcg gccggtgtgc ccggcgccat gcgagcgaca gatgacgatc gatccgaaac
     3481 aggcggcggc gctcgtcgcc gtcgccgata ccggcagctt cgagcaggcg gccgcacggc
     3541 tgcacgtgac cgcgtcggcc gtcacgcagc gcgtgcgggc gctggaggcg agcctcggcg
     3601 cgccgctgct gctgcgcacg cggccgtgcc ggccgacggc cgccggccag cgcgtgctgc
     3661 agcacctgcg ccggatggcg ctgctgcaag tcgatctgca agcggagctc gaagccgagc
     3721 gcggctcgac gatcgcggtc gcgatcgcgc tcaactcgga cagcctcggc tcgtggttcc
     3781 tgcccgcgct cacttcggtg ctcgcgggcg agcggatgct gttcgagctg atcgtcgagg
     3841 atcaggatca cacattcgcg ctgctcgaaa gcggcatggc gatcggctgc gtgacgacgc
     3901 agagcaagcc gatgcgcggc tgcttcgcga cgccgctcgg cacgatgcgc taccggttga
     3961 tcgccgcgga ggaattcgcc gcgcgctggt tcgcgcaggg cctcacccgc gagagcgcgc
     4021 gcgaggcgcc cgtcgtcgcg cacggccggc gcgacacgct gcaatcgtcg tttctgcggg
     4081 acaagctcgg cctgccggac ggcgcgtttc cgtgccatta cgtgccgggc acgcacgcgc
     4141 acttcgcggc cgtgcggcac gggctcggct atgcgatggt gcccgagctg ctgctcggca
     4201 cgacgccgct cgccgagcag cggctcgtcg atctcgcgcc cgcgcattcg accgacgtgt
     4261 cgctgtactg gcacgcgtgg accgtgcagt cgccgaagat ggaatcgctg tcgtcgcggg
     4321 tcgtcgaggc cgcgcagcaa ctgctcgcgc cgccgccgcg cggcgccgcc gcggcgggcg
     4381 ggcgcgccgc ggcggcgccc gctcccgtca agcgcgcgaa cgcgcgaaat acgcgctgat
     4441 cgcggcgaca gccgtgtcga tgtcgtcgcg cgacacgtcg cagtgcgtga cgaagcgcga
     4501 cgcatacagc atctgcgtga gaatcccgcg ctccttgagc catgcttcga gcggcgcgca
     4561 atcggcttcg ggaaattgcg cgaacaccat gttcgtcgcc tgcgacagca ccttcaccgg
     4621 ctcgatgcgc gcgaggccct gcgcgaggcg ctcggcgttc gcgtgatcgt cggcgagacg
     4681 ctcgacgttg tgctcgagcg catacaggca cgcggccgcg agcacgcccg cctggcgcat
     4741 gccgccgccg agcaccttgc gccagcggtg cgcgcgctcg atcagcgcgc cgctgccgac
     4801 gagcaccgag cccaccggcg cgccgagccc cttcgaaaag cagatcgaca ccgaatcgaa
     4861 cggcgcgcac agctcggcga tcgcgcggcc cgacgcgacg gccgcgttgc acacgcgcgc
     4921 gccgtcgaga tgcgcagcga gcccgcggct gcgcgcgagc gcgaccgctt cgtcgacata
     4981 gcccgccggc agcaccttgc cgccgatcgt gttctcgagc gtgaacaggc gcgagcgggc
     5041 gaagtgatcg tcgatcggct tgatcgcggc cgcgatcttc tcgagcggca gcgtgccgtc
     5101 cgcggcgttc tcgatcggct gcggctgaat gctgccgagc accgccgcgc cgccgccctc
     5161 gtatttgtac gtgtgcgcgg cctggccgac gatgtactcg tcgccgcgct cgcagtgcga
     5221 catcagcgcc gcgaggttgc tctgcgtgcc gctcggaaag aacagcgccg cctccttgcc
     5281 cgcgcgctcg gccaccacgg cctgcaggcg cgcgacggtg ggatcgtcgc cccacacgtc
     5341 gtcgcccact tcggcggccg tcatcgcggc cagcatcggc gcgctcgggc gcgtcacggt
     5401 atcgctgcgt aaatcgatca tctgggttcc cgtcggagtc tcgtcgaaga ggaggattgc
     5461 gcggtgcgcc ggcgcgctcg cgcggtgaag cgaaggcttc gagtgtacgc aattcggcgt
     5521 cgcgccgctt gacgcggccg aagcggcgcg ggcgcgacgc ggcgctcgcg cgccgatacg
     5581 gtgagccgtt cgcgggcgca tcggcggcgc cccgccggcg atcaggcgac gaatcggccg
     5641 cgatccggct gtggattcgc catcgacgcg gcgcgcgatc cgtcgcccgc gtcgtaccct
     5701 gcgctcgtcc gggcggcgcc gcgcgcgccg catcgcgccc gcgcccgcat tgccgcggcg
     5761 cggtgaattg ccgcaggcgc gtcaccccgc cgcgcctgcc gctatcacac aaaagcgctt
     5821 caaacttgat accaatcaac gatttaagtc gacaaaccgc ttgcagacgc tggacatctg
     5881 cgacgagttg gcgcatttcg cactgcaaca ccgagcgcga tactcggctc cgactctacg
     5941 gccgcggcct tgcaggcgcg gcgcaggggc cgccggcagc cccgccggcg ggtgtcgtca
     6001 gcttcggtct actcgcatgg aaaccgcttt ttcggccctc gatctggccc gcgtgcagtt
     6061 cgcgttcacc gtctccttcc atatcgtctt tcccgcgctg agcatcgggc tcgcgagctt
     6121 catcgccgtg ctcgaatacc gatggctcaa gaccggcaag gcgtattaca agagcctttg
     6181 cctgttctgg tcgaagatct tcgcggtcgc gttcggcatg ggcgtcgtct ccggcgtcgt
     6241 gatggcgtat cagttcggca cgaactggtc cggcttctcg agcttcgccg gctccgtcac
     6301 cggcccgctg ctgatgtacg aggtgatgac cgcgttcttc ctcgaagcgg gcttcctcgg
     6361 catcatgctg ttcggctgga accgcgtgag cccgcgcgcg cacttcggcg cgacgctgat
     6421 ggtcgcgatc ggcacgctga tctcgacgtt ctggattctc gcgtcgaaca gctggatgca
     6481 gacgccgcag ggcttcgaga tcgtcgacgg ccaggtcgtg cccaccgact ggttcgcgat
     6541 catcttcaac ccgtcgttcc cgtaccggct cgcgcacatg gcgatcgccg cgttcgtcgt
     6601 cgccgcgctc gtggtggccg cgacggccgc gtggcacctg ctgaagggcc gccgcgacaa
     6661 ggccgtgaag aagatgttct cgatgtcgct gtggctgttg ctcgtgctcg cgccgctgca
     6721 ggccgtgatc ggcgatcagc acggcatcaa cacgctgcgc caccagcccg cgaagctcgc
     6781 cgcgatcgag gggctgtggg aaaccgagcc gggcggcacc gcgctgaacc tgttcggcat
     6841 tcccgacatg aaggcggaaa ccacgcgtta cgcggtgtcg attccgcatc tcggcagcct
     6901 gatcctcacg cacagctggg acggcgagat ccgcgggctg aagtcgttcc cgccgcaaga
     6961 ccggccgaac tcgaccgtcg tgttctggag ctttcgcatc atggtcgggc tcggcctcgc
     7021 gatgatcggc ctcgccgcgc tcgcctggct gctgcgccgc cgcgggcgcc tctatgaagc
     7081 gaagtggttc caccggttcg cgctcgcgat gggcccgacg ggcttcgtct cgctgctcgc
     7141 cggctgggtg acgaccgaag tgggccgcca gccgtgggtg gtctacggcg tgatgcgcac
     7201 gtcgcacgcg gtgtcaccgc tgtcgacgca gcaggtgagc gtctcgctga tgacgttcgt
     7261 cgtcgtctac ttcctcgtgt tcggcacggg cgtctactac atgctgaagc tgatgagaaa
     7321 gggccccgcg ctgccgggcg acacgcccga cgatgcgcac gacgcgcggc ccgagcgcac
     7381 cgcccggcgc ccgctgtcgg ccgcgaacca gttgatcgac gccgcgtgaa gccggcgcgc
     7441 caccaagcca agcgaggtta gcaaatggat gtcaccgtaa tctgggccgc gatcatcgca
     7501 ctcggcctgt tcatgtacgt cgtgctcgac ggcttcgacc tgggcatcgg catcgtgttt
     7561 ccgttctttc ccgccgaaca ggagcgggac ctgatgatga acaccgtcgc gcccgtgtgg
     7621 gacggcaacg agacgtggct cgtgctcggc ggcgcggggc tcttcgcggt gtttccgatc
     7681 gtctactcga ccgtgctctc ggcgctgtat ctgccgctcg tgttcatgct cgtgtgcctg
     7741 atctttcgcg gcgtgtcgtt cgagatccgc gcgaaggcgc gccgcaccaa gcacctgtgg
     7801 gatctcgcgt tcatcggcgg ctcgacgggc gcgacgttct tccagggcgt cgcgctcggc
     7861 gcgttcctgc agggcattcc cgtcgacggc ggccgcttcg cgggcgacgc attcggctgg
     7921 ctcacgccgt tcagcctgct cacgggcctg gggctcatcg cgacctacgc gctgctcggc
     7981 tgctgctggc tcgtcgcgaa aacggaaggc gacctgcaac ggcggctgca tcgcgtcgtt
     8041 tggccgctca ccgtcgtgct gctcggcttc atcgcggtgg tgagcctctg gacgccgctg
     8101 caggacacga acatcgcgca gcgctggttc gccacggggc tgttctggcg gctgctgccg
     8161 gtgccgttcc tcgtcgccgg ctgcgcggcg ctgatgcgcc gcgcggtgcg cgagcgccac
     8221 gacacgacgc cgttcgcgct cgcgctcgcg ctcgtgttcc tcggctacgt cgggctgctc
     8281 gtgagcctgt ggccgtatgc gattccgcag agcgtgacgc tgtgggaagc cgccgcgccg
     8341 cgttcgagcc agacgttcac gctgatcggc gcggccgtca tcattccggt catcctcgcg
     8401 tacacgacga tgggttattg ggtattccgc ggaaaggtgc gtcatgaaga ccagcattac
     8461 taccaccact gagccgcgcg ccgtcgcgcg cggcgcgcgg ctgccgggct ggatgtggtt
     8521 cgcgctgctg tggatgggcg gcgtcgcggg cgcggtgacg ctcggttacg cgttcaagct
     8581 gttcatgtac gcgacgctgt tcgccgtgaa gtagtggcgg tgaggcggac gtgaaacgac
     8641 gccgcgcgat gcggcgcgga gcgacgtgcg gcatctgacg tgcgacatct gacgcgcaat
     8701 gagcgacgtg tgacgtacgg ccgattgcag cgcgtcaacc ggcggcgcgg cggcgcgggg
     8761 catcgcaggc gccgccgtct ctcagtcatc cgacgcgaag tggcttcgcg atgaaatcgc
     8821 gccgccgcga gaaaccggcc gcgcgccgct tcgccacagc ggggctcgac gcaggaagga
     8881 gaacgcgcgc cgccggcgcg atatcgcttc gccgtgtcgg cggcgcgcgc ccgcgacacg
     8941 cgccggccgc gcgctcagga acgccggccg agtgcctctt cgatcttcct gtcggtcttg
     9001 tactggctga gcgcgtacac ggaccagatc gccgcgggca gccagccgat cagcgtgatt
     9061 tgaaggatca ggcagatgat gcccgcgaac gggcggccga tcgtgaaaaa ctgcagccag
     9121 ggcagcagca aggcgagcag aagacgcatc gtgttttcct cttggtcgga tcgccgacga
     9181 tcgacatgga tcggcgcgta gatggcggcg cggcgccgac attcaagttc cgcgccgccg
     9241 gcccctgcgt ccggccctcg gtcgctttcg ccgccggccg gcctgcgccc ggagccgtca
     9301 cgcgatcgtt atagcagatc gggaattaaa ccgggcttaa agccacgcga cgcgggccgg
     9361 cgcaaggatg tgagggacga gcgtgcgcgg ccatcgcgag cgcttcccgc gcgtggagct
     9421 ggagctgaac agcaacgagg gcgtcatcga tctgctcgag cggcgcaccg acgtcgcgat
     9481 ccggatcggc cgcctgaagg attcgacgct gcatagccgg ctcaccggca acagccggct
     9541 gcgcatcctc gcgagccccg cgtatctcga cgcgcaaggc cggccgcgca aggccggcga
     9601 tctcggcaag catgcgctgc tcggcttcaa tcggccggaa tcgctgaacg tgtggccgac
     9661 ctcggcgcgc acggcgagcc ttgccggatc gcgccggccg tgtggtcgtc gcgcggcgag
     9721 acgctcagac agctcacgct cgacggcgcg ggcatcgtct gccggtcgga tttcatgacc
     9781 gcgcaggatc gcgaagcggg ccgcctcgtg cagatcctcg cgcgccacac gcaagacgtg
     9841 cggcagccga ttcatgcggt ctattaccgg aacacggcga tttcgtcgcg aatcgcgtca
     9901 ttcgtcgatt atctgatcga cgcgctcggc ggcgggaatg ccgcgcaaaa ggcggcggcg
     9961 tggacgcgtc cgtgacgcgc gcggccgggc gcgccgcgca tcacgcgatg agccgcgcct
    10021 cgacgtccgc gatcaggcgg tcgagccacg cgcgcagcgc gccgttcgac atcgcgagcg
    10081 gcagcgaata cgcgaggatc cggtagacgt cgccgcgccg caccttcgac gcgcgcgccg
    10141 gatcgagcca cgcgtcgttc gacgcgagca gcgcgagcgt ccgcaggccg atcgcgatcg
    10201 gccagaaaca ggcaagccgc aggcgcggcg cgcggcgcgg aatcgcgaac gtataatcga
    10261 tgcccgcgcg aaaatgcgcg agcgtcgtgc gcacgagcgc atgcatcagc ggccgtacgc
    10321 gcagcgaagc gtccggcccc agcagatcct ccgcgcgcag cccgtattcg tccagcatcg
    10381 cctgcggcag atagcagcgg ccgatccgca ggtccctgcc gcagtcgcgc agcacgttgg
    10441 tcatctgcag cgccttgccg aagcggatgc cgcgctcgct catcgtgtcc tcccgctcgg
    10501 tcagcagccc gggcagatgc gcgcacgtca tcttcgtcca gaattcgccg acgcagccgg
    10561 caacgagata cgtatagcga tcgagcgccg gccattcccg cagcgcgacg atgcggcccg
    10621 acgattcgtc cgggaacgtg cgcaaatcga attccatccc ttcggtgagc gtggtgacga
    10681 cgccgcgcac cgcggcgcga tcgggcgcgc tcaattgcga cagcaccgcg agcgcggggc
    10741 cgagcgattc gagcagcgtc ttctcgtccg tctgcgcctg ctgccccgcg acctcgcccg
    10801 cgatccgcgc gagcgcgtgc ggatcgggcg cgccgttgat ctgcgcgcgc agcgacagca
    10861 gcagttcgag ccgctgagcg ggcgggatca gcgacgtgtc ggcgatcgtg tcggccgcgc
    10921 gcgcgagcag atacgcaagg ccgatcgggt cgcgcatgcc ttgcggcagc acgcgcaacg
    10981 tcagatagaa ggagcgcgac acgcccttca gcagggggcc cagcagaaag gctcgggtgg
    11041 aattgcccat ggatcggatc aggtcggtca tacgaatggc tgccgcattg tatcggcaaa
    11101 tgcgcgcggg ccgccggcgc ttcgcgcacg gccggccgcg cagggtgcga ccgggcgcgc
    11161 cgcacggcgc gcggcggccg atatccgcgc cgcgcggcaa tgcgtacaat cgcatccttt
    11221 cctgcaagag gtgaccgcga tggcgatgaa gaaaaccgat ctcgagaaga acaaggcgtt
    11281 gaagctgacg cacgcgatga agcagacgac atccgcgcgc ttcggcaagg gcgccgaaga
    11341 tgcggcggcc gatcgccgcg agcggcgcag gctcgaacag gcgcagggcc tcgtgccgtt
    11401 cgcgtgcaag ctgaacatcg agctcgtcgc gcgcctgaac gagcgggcgg ccgcgcatcc
    11461 ggacgggatg accggattgt tgaccgaact gttgcaacgc ggcctcgacg aaaccgcgaa
    11521 gtaaacggcg cgcgcaccgc acggcgcaca cggcgacgtt gcgcaggggc gccgccgcgt
    11581 tttcggccta tgctgaaaac gcagctgcgc aacaccccgt tcgtcgactc ttcgaaaaca
    11641 ggagtgccgt gatgaatcct cccgttctgc gcgtcgcccg gccgaccaac gatatcgaca
    11701 cgctcgtgcg tttctacacg aaggcgctcg gcttcgacgt cgtcgcccgc ttcgagaatc
    11761 acgaaggctt cgacggcgcg atcgtcggcc gcgccggcta tccgtggcaa atcgaattca
    11821 cgcatcagca cggcgtgacg gtcgcgcgcg caccgaccgc cgagcatctg ctcgtctttt
    11881 atctgcccga tcgcggcgcg tggaccgagg ccgtcgcgcg aatgcgcgcg tacggcgcga
    11941 cgccgtgccg ctcggagaat ccgtactggg accgcgaagg cgtgacgttc gaggacccgg
    12001 acggctaccg gatcgtcctg cagaacgcgc agccggcctg aacgctcgca cgcggccgcg
    12061 cccggaccgc gcgcggcggg tggtgcgcgc gcgatgcggc gcacagccgc gcgccggcag
    12121 ccgccgcgtg cggcgcgcgg cgtacgcacg cgtaatgcgg cacgcgtgat gccgcgcggc
    12181 gcaattggtt gcacgcgcaa ccatcatgag cggcgtcgcg gcgctcgtcg agcgcgccgc
    12241 gcgatcccgc cgcgcgccgc ttcggcgcga cgccgcgcat gcccgatcgt ccgccgcgct
    12301 gccgcgctgc cgcgccgtcg cgccgacgaa cgagataccg gcaacggccc gccacccacg
    12361 cgacacctgc attcgcgcgc gccgccgcat accgctcgaa cgcacgcctg gcggttcccc
    12421 ccgcagcgca acgcccctct cgccgtcgcc ccgaacgtcg ccgcgcacgg cggcccgccc
    12481 ccccgccgaa acacattctc acaacttcgc cgcaccgctc gtcgcgcagg cgccgcgcgc
    12541 cgccgcgcgc gccgacagac aaacgaaagc ggcgcgtcac gacgcgttag caatccccgt
    12601 gcaaattgcg gctccgggtg tgggacacag ccgttctaac gacgaggtca acgatgaaac
    12661 gcaacagtaa gcagttcgaa atcggcgcat ggctgggcgc gtgcgcgctc gccttcgccg
    12721 gcgcggcctc ggccgccgcc gtccaggatc gcgatcacga cagccgcccc gtcgacgcga
    12781 agcgcgtgct gctggcgagc attgatggtc tgcacgagca ggacctcgcg cgctgcatcg
    12841 gcgcgaatac gtgcccgaat ctcgcgctgc tcgcgaagtc gggggtcacg tacacgaacg
    12901 cgcgcacgcc ggggctgtcg gattcgttcc cgggcctggc cgcgctggtg acgggcggtt
    12961 cgccgaagag cgcgggcctc ttctacgacg tgtcgtacga tcgcacgctg tacgcgccgt
    13021 cggatgcgac gtgctcgggc aagcaaggct ggaacgtcgt gttcgacgaa acaaccggca
    13081 tcgacgcgat gaacggcggc gcgctcacgc atctcgacgg cggcggcgcg ttcaacccgc
    13141 aggcgatccc gcacgcgcgc gtgaacggcc agtgcgtgag cgtctatccg cacgactacg
    13201 tgaagacgaa cacggtgttc gaagtcgtca aggaacatct gcgcggctcg cacaccgcat
    13261 gggcggacaa gcacgcgtgg ggctacgact gggtgaacgg cccgtcgggc aagggcgtcg
    13321 acgatctcgc gcgcaccgag atcaactcga tcgatccggc cacgggcacc ccctacaccg
    13381 acatctatac gcataccgaa aagttcgacg actatcacgt gcaggcgatc gtcaaccaga
    13441 tcgacggcaa gaactcgacg ggcaccgcgg ccgcgcccgt gccgaccctg ttcggcacga
    13501 acttccagac gctgtcggtc gcgcagaagg ccaccgtcgc gtcgggcggc ggctatctcg
    13561 acgcgagctt cacgccgggg ccggaagtcg cgaacgcgat cgcgtacgtc gacggcgcgc
    13621 tcggccgcat cgtcgccgag ctcaggcagc gcgggctgta cgattcgacg gtggtgatcg
    13681 tcaccgcgaa gcacggccag tcgccgaccg accatacgaa gctcgtgaag cacggcgaca
    13741 cgctcaccgc gctgctcgag gcgaacggct tcgtcgatcc gaacggcaac ttcggccaga
    13801 acaacaccgc gtcgggcaac ccgaacgacg gcacgggcct cgtcggcacg ggcttcgtgc
    13861 agaccgacga cgtcggcctc gtctggctgc gcgacccgcg ccagttgagc gcggccgtcg
    13921 cgacactgaa ggcgaatctc ggctgcaacg cgccggggat ctgcgcggac ggcccgcagg
    13981 cgtacatcct gtatggcccg agcgtcgccg agcgcttcgg caatccggcg ctcggccgca
    14041 cgccggacat cgtcgtgcag ccgaacccgg gcgtgatcta cacgtcgagc aagaagaagg
    14101 acgaagagca cggcggcaac gcgccggacg acagccacct cggcctgctc gtgtcatacg
    14161 cgggcttgcg ccagggccgc acgatcgacg cgccggtgct gacgacgcag gtcgcgccga
    14221 cgatcctgcg ctcgctcggc ctcgagccgc gcctgctgca cgcggtcgcg ctcgaaggca
    14281 cgcgcgtgct gccgggcctt ggcctcgagc gctgacgcaa gcgccacggg agcgcgccgg
    14341 cgccgggcga ggccggcgcg ccccgtggcc ggcggccgcc ccgacacggc ccgacccgcc
    14401 gcgacggaac tcgcccctca accgcgccgg cgcaatgcgc ggccgcgcct cgcgccggct
    14461 tcgcccgatc gtgccggctt cgccgcgacg cgctcgccga gcgatcggcg gcgcgcgctc
    14521 gcagcccgcg ccacggcgcg cccgcgcgct cacgcgcggc cccgccctct cgcctgcgcc
    14581 gccccctcgg ccgctccgcc atcgcgccgc aacaattttt tccgggttgg cggcggacta
    14641 ttgtcatgcg ataagaagat cgtccttatc cggagcatcc cgatggccac gctggaagcc
    14701 ttccgatgcg tgctcgacga cgcgcgcacg cccgagatca ttcgtcatca catcatcgac
    14761 gcgctgcaat acgcactgcg taattacggt caggtgttca ccgcgaagga agtcgaatgg
    14821 ctggccgcgt gggacgaccc gcgcattccg ctcgccgcgc gcaaggagct cgaccggcgc
    14881 gagccggccg ccgccgcgcg ctgacgcggc gcgccgcccg cgccgcgcgc aaaggccgcg
    14941 cgcgccggca aaaaaaggcg gcgcagccaa agccgcgccg ccttcgtcgc cttcgcgccg
    15001 tctctcgctg cccggcgcgg cgcgcgccgt cacttcaggc cgaagtcgac gcgcgtcgtc
    15061 gcgcccttgt cctcgatgcc cttcgcgtcg agcttcggcg cgacgatgaa catccggctc
    15121 gaatcgacct tgccctccag gtactggcgc accgcctgcg cgcgcgcctg agcgagcgcg
    15181 cgcaggctcg agtcgtccac gctcgcgtga tcggcgagcg cctttctcat gtcgtcgtcg
    15241 ggcaacgtct tcgtgaagcc gatcatgttg cgcggcttct tgaaatcggc cgccttgtac
    15301 gccttcgtca ggtacttcgt gtattcggcg ggatcgacct tcaccgtcat cgggtcgacg
    15361 ctctcgccct ggccgaccac gtccttcagc ttctgctgcc gcacgagccg ctcgacgtac
    15421 gcgtcgcgca gccccggcag atccttgtcc ggatcgacgc ggccgatcag gtcgaggcgg
    15481 atcgagggct tttccgcgag catcttcgag atcgtgtcga gcttcttctg cgacgcgtcg
    15541 gacagcttcg agcggcccgg ctcgaattcg acatagccga gcgcctcgcc gtcgccgccg
    15601 aacgcgtgcg cgagcagcgt gaacggcgag gtgacggcct tcgcgatcag gttcagcacc
    15661 gcgcgccaga tcagcccgcc aatgctgaac tccgggttcg acaacgaacc ggacaccggc
    15721 acgttcacgt cgatctcgcc gcgcgagttc ttcaggagcg cgatcgcgag ccgcaccggc
    15781 agcttcgtcg cggtgtcgtt ctcgacgtgc tcgccgaacg tgagctgatc gatgaagatg
    15841 tggttgttcg cgctcagcag atcgttgtcg agcttgtagt gcagatcgac gttcagcttg
    15901 cccttggtga tcggatagcc cgcgtacttc gccgaatacg gcgtgaggtt cgtgagctcg
    15961 atgtcgtgcg cggtcgcggt caggtcgagc gacggcttct cgatcagcgg gttcaccgtc
    16021 cccttgatcg tgatcgggcc gttgccggcg aggttcgcgc cgacatcgac gggcgcgggc
    16081 gccgtcgaat cggtgccgaa cgcgccgatc gtgccgttga tcgcgacgag gttcgccgtg
    16141 tagttcggct tgatgaagtt atcggtatac gtgacgcggc cgcgttgcag cagcaactgg
    16201 ccgaagtgca gccgcaccgg atgctgcggc ggcgcggccg cgcgcacgac ggccgcgccc
    16261 gacgcgggcg acgnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntcgctcg
    16381 acaactcgcg gcacactacg gcaaagcgcc ccgcctcgtg cggggcgtca gactgctgac
    16441 gaataagact cgtttaattc tggggcgtca ggctgctcac gaaccccacg ttcgcgtgcg
    16501 cggcgggtgt ggtctttctg ggatcaggat tgcggcggcg aagaccgtcc aacgcaagac
    16561 aggatcggag gaaacgatgg tcgaagatac cgttttcagc ggcctgcgca cgttactcac
    16621 gcacgaacac gcgttcccgg tgcaaagctg ccgcgtgtcg atcgagatgc aacgcccgtg
    16681 ggggcgcccg taccggctcg tcgaatggac gatgcacctc gacgcgcccg cgcgccggcg
    16741 catcgtgccg gccgagagca ccgaggcgga aatcgccgag gcggtcgcgt cgcacgtgcc
    16801 cggacgcctg tacgaaggcg gcgccgcgct gtattgaacg cgcgcggccg ggccgaacgc
    16861 cggccgagtt cgtagacgtt cgccgcgaac cgggatcgcg gcaggtccac gcggcgcaag
    16921 cgcgctcgcg gcgcaccgcg cggcatcgta ctccgtcgtg ctccatcgtg cgacaagccg
    16981 cgattcgatc cggaccgcgc cgagcgcgaa aacgccgccg ccgatcgcca ctgttcgctt
    17041 ttttcgtttg attcccgctt gtttttccgc gcgcgccgct cacggccctc gtggcacgcc
    17101 ggtcttcgca agccgcgttc ccgcgtcgcc cgcgcgagcc gcgcgcgatt gcgttggaat
    17161 ccctttgccc gcattcgtcg ccatagccgg cagtcctgac cgattttccc gctcgcgccg
    17221 ggcgccgggc gccgtcgatc gcggcccgtg cgtcgccggg tcccgttcac gcgccggtca
    17281 aatctgctac gctgcgcgtt ttcgattcgc acccatttga tggaaaacgc cttcaacgaa
    17341 cgcggcgtca tggtcacgcg caacggcctg tccgccgccg ggcaaatttt cgcgctgcgc
    17401 gagatccgcg gcgtcgaggt tcgcaccgtc aggaaaaaca agctcgtgcc gtgcgcgatt
    17461 tcgctgacgg gcgctgccgc cgcgatcgcg ggcggcgcgc tcggctcgag cgcgctgctc
    17521 gtcgcgggcg taatgctcgt cgtcgtcggc tatctcgcgt ggacgacgca ggacgtcacg
    17581 catcggctga tcgtcgacat gccggacggc aagcgcgagg cgatcatgag cgtcgaccgc
    17641 gaattcgtcg agcgcgtcgc gcacgcggtg gacgccgccc gcgcggccgg cgcgtcaact
    17701 tgacgcaccc cgccgcgctt ttcaagattc gcgccgcgca ggcgagcgac gccgccgcat
    17761 ggcggcagct tcgccgcgcg ctgtggccgc acgcggacga catcgaacat gcgcgcgaca
    17821 tcgcgcggca gctcgacgcg cccgcgcgcc acgcgtgctt catcgcctcg ccgccgggca
    17881 tcctcgcgcc ggtcggcttc gccgaagtcg ccgtccggca cgatgacgtg aacggttgcg
    17941 gcgcgtcgcc cgtgctgttt ctcgaaggcg tgttcgtcga gccggccgcg cgccgccgcg
    18001 gcgtcgcgcg cgcactgtgc gcggcggcgg ccgcctgggg cacggcacgc ggttgcgcgg
    18061 cgttcgcgtc ggacgcgccg ctcgagaacg ccgcgtcgca tgcactgcat cgcgcgctcg
    18121 gcttcgacga gaccgagcgg gtcgtgttct tccgcaagcc gctcgcgcgc tgagcgcggc
    18181 cgccgcacgc ggtcagccgc gcccggtcaa ttcagccgcg cgccgatcga gctcgcgagg
    18241 ctgcacagaa tcaggcagca cgacgccgcg ccggcatcga gcgtgccgac cgagcgctcg
    18301 ccgagcctcg acgcgcgccc gaccctcgcc tgcagccagc gcgtcgattc cttgccgcgc
    18361 tcggcggccg cgctcatcgc cgcgagcgca tgccggaagt cgtcgcccgc gcgtagcgcc
    18421 tcgtgaaacg ccgcggcggc gggcgcgagc gtgtcgatca gcgtcttgtc gccgatcttc
    18481 gcgtcgctga tcgcctgcac gcccgcgaac cccgccgcca gtgcctcgcc gaacagcgcc
    18541 gcgtcgagcg tgtcgcgccc cttcagcggc gcggcgaaat ccatgaagaa gctgccgtac
    18601 agcgggccca tcgatccgcc gatgccgtcc atcagcgccg tcgacaacac gtcgagcgcg
    18661 tccggcaggc tcgtcgcgcc gcgcgcgtcg agccgcgcgc cgcactggcc gaagcccttg
    18721 ctcatgttga tgccgtgatc gccgtcgccg atcgccgcgt cgatctccga cagatgatcg
    18781 cgattgcgcc ggatcacgtc gacgagctcg cgcacgacga agccggcgtc ggcgagcggc
    18841 aggcactgaa tggcggcggt attcatgcgc gttctcccac ggtgaggccg atgctgctgc
    18901 acggcgcggc gaacagttgc ttcaactcgt cgtcgagccg ggtgacggtc agcgtgacgc
    18961 ccatcatctc gagcgacgtg aacagattgc cgacgaggcg aaagccgatc ttcagcccag
    19021 cggccgcgag ccgctgcgat acttcggcat acagaatgta ctgctccatc agcggcgtcg
    19081 cgccgagccc cgacaccagc accgcgactt cctcgccgcg ttcgagcggg aaatccggca
    19141 gcacgatgtc gagcatcatc gccgccatgt ccttcgcgct caccgtgcgc atcacgcgca
    19201 cgccatgctc gccgtgatgg ccgatgccga cctccatctc gccgtcggca atgtggaagt
    19261 tcgccttgcc gttcgccggg atcgtgcacg cggacaggcc gatgccgacc gagcgcgtgt
    19321 tgtcgatcgc cttcttcgcg ctcgcgatca cggcgtcgag atcgccgccc gcggccgccc
    19381 gcgcgccgcc cgccttccac atcaggatct cgcccgcgac gccgcggcgc ttcgcgcgct
    19441 cctcgcgcgg cgcggacgcg acgtcgtcgt tcgcgacgac ggtcttcacg tcgatgccct
    19501 gcgcggcggc catcttgatc gccatcttca cgttcatgtt gtcgcccgcg tagttgccgt
    19561 acaggcaggc gacgcccgcg ccgcgatcgg cgcgcctgaa cgcgtcgaga aagctcttcg
    19621 cggtgggcga cgagaagatc tcgccgatcg cgaccgcgtc gacgagcccc ggccccgtgt
    19681 agccgacaaa cgccggctcg tggcccgagc cgccgcccgt gacgacgccg accttgcccg
    19741 gcaccggatg cgcgacgccg atcacgcgcg ggttgtccgc gtcgagcgcg agcgccggat
    19801 gcgcggcgac gatcccgcgc agcatgtcct cgacgacgta gtcgggatga ttgatgacac
    19861 gattcatgca attaacctcg cggatccaga acgaccttca acgattgctc gccgcgctcc
    19921 atcacggcga acgcgtcggc gaagcgcgac agcgggaacg tgtgcgtgac gatgccgcgc
    19981 acgtcgatcc tgcgcgatgc gatgaactcg atcgcgcgcg ggtacatgta cgggccgaga
    20041 tgcgagccga gcacgtcgag ctccttgcga tcgccgatga tcgaccagtc gacgctcgct
    20101 tcgtcgttga acacgctgaa ctcgacgaag cgcccgagct tgcgcagcat cgcgagcccc
    20161 tggcctaccg cgcgatggtg gccggtcgcc tcgatgtaga tatcgcagcc gtagccgccc
    20221 gtgatcgcgc ggatcttctc gatcacgttc tcctcggccg ggttccacac gtcgtccgcg
    20281 cccatccggc gcgcgagcgc cgcgcgctcg ggcttcatgt cgagcacgat cagttgcttc
    20341 ggatggcgca gccgcaccgc gccgatgatg ccgagcccga gcgtgcccgc gccggcgacg
    20401 acgaccacgt cgtcgaagcc gacgttcgcg cgatcggccg cgtgcagcga gcacgacagc
    20461 ggctcgatca ggatcgcctc gtcggtcggg atcgaatcgg gcacgcggtg cacgatcgcc
    20521 tccttcgtga agatcatgta ttcggccatc gcgccgtgca cgttgttctg gaatccgtac
    20581 agatcatgct tctggcacat ccagtactgg ccgtggccgc agaagcggca gctccagcac
    20641 ggcacgatct gctcggagat cacgcgatcg cccgccttca cgccgcgccg ctcggcgccg
    20701 gggccgagcg cgacgacgcg gcacacgaat tcgtggccgg gaatcatcgg cggcttcacg
    20761 tagcgcggct gcaccgcgtc gccccagaac gacggcgcgc cgcgaaacgt cttgatgtcg
    20821 cccatgcaga tgcccacgcg ctccacctgg gtcaggatct cgtccggccc cggcttcggc
    20881 accggcacct gctcgaggcg gtagtctcgc gggccgtggc aaaccacggc gcgcatcgtg
    20941 gcgggcagcg cgggcgtctc gccgcgctcg gccgcgcgtt gcggcggcgc ttcggctgtc
    21001 tgtggcatgc gttgtctcct gtgctgtgtg tcggtcgatc ggggagggcg
//
