LOCUS       NZ_KN150952            28069 bp    DNA     linear   CON 15-JAN-2024
DEFINITION  Burkholderia pseudomallei strain BEC scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KN150952
VERSION     NZ_KN150952.1
KEYWORDS    WGS; RefSeq.
SOURCE      Burkholderia pseudomallei
  ORGANISM  Burkholderia pseudomallei
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3317933)
  AUTHORS   Daligault,H.E., Davenport,K.W., Minogue,T.D., Bishop-Lilly,K.A.,
            Broomall,S.M., Bruce,D.C., Chain,P.S., Coyne,S.R., Frey,K.G.,
            Gibbons,H.S., Jaissle,J., Koroleva,G.I., Ladner,J.T., Lo,C.C.,
            Munk,C., Palacios,G.F., Redden,C.L., Rosenzweig,C.N., Scholz,M.B.
            and Johnson,S.L.
  TITLE     Whole-genome assemblies of 56 burkholderia species
  JOURNAL   Genome Announc 2 (6), e01106-14 (2014)
   PUBMED   25414490
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3317933)
  AUTHORS   Bishop-Lilly,K.A., Broomall,S.M., Chain,P.S., Chertkov,O.,
            Coyne,S.R., Daligault,H.E., Davenport,K.W., Erkkila,T., Frey,K.G.,
            Gibbons,H.S., Gu,W., Jaissle,J., Johnson,S.L., Koroleva,G.I.,
            Ladner,J.T., Lo,C.-C., Minogue,T.D., Munk,C., Palacios,G.F.,
            Redden,C.L., Rosenzweig,C.N., Scholz,M.B., Teshima,H. and Xu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; AllPaths v.
            39750; phredPhrap v. SPS - 4.24
            Assembly Name                     :: BEC
            Genome Coverage                   :: 279.0x
            Sequencing Technology             :: 454; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/15/2024 02:29:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,952
            CDSs (total)                      :: 6,888
            Genes (coding)                    :: 6,565
            CDSs (with protein)               :: 6,565
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 131 of 323
            Pseudo Genes (incomplete)         :: 228 of 323
            Pseudo Genes (internal stop)      :: 25 of 323
            Pseudo Genes (multiple problems)  :: 51 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:39:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 286872
            Orig. end                         :: 314941
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KN150952.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28069
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="3"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..28069
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28069
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:18069](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18069
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            314..1480
                     /locus_tag="DO72_RS01190"
                     /old_locus_tag="DO72_2003"
     CDS             314..1480
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004544567.1"
                     /locus_tag="DO72_RS01190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_2003"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_004544567.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.4e-34,
                     bitscore: 115.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHTETSIKSLQIGMHWFPERAGGLDRMYYSLVGALPSAGVAVRG
                     VVAGSERVAADTGGAIRGFGPATSSLPRRMIAARHALRDVMRIERPDVVSSHFALYTFP
                     GLDVTRGIPQVSHFQGPWADESHVEGADSLGQKVKHRLEQAVYARSSRLIVLSHAFGQI
                     LTSRYNVDPARVRVVPGCVDTAQFDLPMTPADARRKLQLPQDRPIVLAVRRLVRRMGLE
                     DLIDAVKTVRRRHPDVLLLIAGKGRLEGELRKRIDDAELGENVKLLGFVPDNHLAALYR
                     AATLSVVPTVALEGFGLITVESLASGTPVLVTPVGGLPEAVAGLSEALVLPEVGAAAIA
                     DGLAAALSGSLVLPDADACRRYARAHFDNTVIARRVAEVYEEAIRAAV"
     gene            complement(1769..2536)
                     /locus_tag="DO72_RS01195"
                     /old_locus_tag="DO72_2002"
     CDS             complement(1769..2536)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895622.1"
                     /locus_tag="DO72_RS01195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_2002"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_004544598.1"
                     /transl_table=11
                     /translation="MTRLAAPSLSLRRYGAVQASDVHDFHQIVLGVDGAMTMTVDGVDE
                     RIDRRCAWLIPAGARHDYAGLADNSQLVLDLPPGSLAVPERLFERARTMAIDPGLTTLV
                     GELASRIARGPLADAASARRLHWQAAARLCGALVGELGGAPSQPAVGLDFARIDGWLRA
                     HLAQPLRIADLAAHCGFGMRRFHQLFCEAFGETPHRYLQRLRLDAAVMLLGDPKHSLTD
                     IASEVGFADQSAFTHAFTKRFGLAPGRWRSDRH"
     gene            complement(2599..2940)
                     /locus_tag="DO72_RS01200"
                     /old_locus_tag="DO72_2001"
     CDS             complement(2599..2940)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004537279.1"
                     /locus_tag="DO72_RS01200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_2001"
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_004525093.1"
                     /transl_table=11
                     /translation="MTVVTTESGLKYEDLTEGSGAEARAGQTVSVHYTGWLTDGQKFDS
                     SKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGVIPPNATL
                     VFEVELLDV"
     misc_feature    3166..3175
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(3220..3426)
                     /locus_tag="DO72_RS01205"
     CDS             complement(3220..3426)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004548817.1"
                     /locus_tag="DO72_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004548817.1"
                     /transl_table=11
                     /translation="MVAGNVREGPRERHAARKPVAAHADRAFARSDVSAPSRLHGHRAQ
                     KAPPGLAPAARARSLAADLYINN"
     gene            3444..4352
                     /locus_tag="DO72_RS01210"
                     /old_locus_tag="DO72_2000"
     CDS             3444..4352
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020415508.1"
                     /locus_tag="DO72_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_2000"
                     /product="metal-dependent hydrolase"
                     /protein_id="WP_004525095.1"
                     /transl_table=11
                     /translation="MNQPAKSTDPVSVMPVRRDLRFNLPVERATDWHGQGSQVSHFFNA
                     LSLLFPAGERFFMDSVRNYRDRIDDPVLKKQVLGFIGQEAMHTREHVEYNELMHANRLP
                     ARTVDRRVWKVTGWMKKVLPHSVQLAHTVAAEHYTAMLANWLLSEPAALAGSHEGYKQM
                     WLWHALEETEHKAVSFDVWNTVMKPGPKRYLIRIGVYLLTTMTFWPNVFLIHSQLIRWD
                     RKSDKSVRGLWRVVSLLYGPRHGMFPAIAREWLSFFRPDFHPWDYDNHHHLARVDAIVE
                     ATQAREARKLAAVELDGAKPA"
     misc_feature    complement(5017..5030)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.41"
                     /tool="antismash"
     gene            5081..5500
                     /locus_tag="DO72_RS01215"
                     /old_locus_tag="DO72_1999"
     CDS             5081..5500
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895626.1"
                     /locus_tag="DO72_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1999"
                     /product="MbcA/ParS/Xre antitoxin family protein"
                     /protein_id="WP_009926546.1"
                     /transl_table=11
                     /translation="MSRPALKPFSTPPEATVEQMSAAGLRAFFNIARDWNLSTDEQLVL
                     LGSPGRSTFFKWKASPQTARLTHDTLERLSLVLGIYKALQILLPQPAAADSWVKRPNDA
                     APFNGKRALDRMLAGNVSDLVAVRQYLDAARGGWA"
     misc_feature    complement(5098..5109)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            5491..6198
                     /locus_tag="DO72_RS01220"
                     /old_locus_tag="DO72_1998"
     CDS             5491..6198
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019255919.1"
                     /locus_tag="DO72_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1998"
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="WP_004525098.1"
                     /transl_table=11
                     /translation="MGVTSPERQTNWPTASLDWAPAYRVIPTRFPAINLFDRVASAEDF
                     DALYALEALTNDRVRTEVGMLDLVPPQERRFGPGYGPIMAAFTHLNPNGSRFSDGSYGV
                     FYCARARNTAIAETRYHTSLFLAATKEPPMRQQMRLYTVVAQGEVADVRAWRERDPALL
                     DLVDYSAGQALGRAVRDAGGAGIAYPSVRDPGGECLAAFRTTLLHDCRHAAYLEYNWNG
                     AAIDAVFELNQVG"
     gene            complement(6299..7033)
                     /locus_tag="DO72_RS01225"
                     /old_locus_tag="DO72_1997"
     CDS             complement(6299..7033)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525100.1"
                     /locus_tag="DO72_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1997"
                     /product="metallophosphoesterase"
                     /protein_id="WP_004529074.1"
                     /transl_table=11
                     /translation="MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARD
                     RLFSVGDLVDRGAQSEAALALLERPWFHCVLGNHEDVLCSVADGKLPMSVWQRIGGEWA
                     ADLPAATLARHARRLRELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVITRLL
                     WGRELAYGRTDPAARQAGLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKS
                     GESWSMSVAAARHQGAADVPLP"
     gene            7155..7808
                     /locus_tag="DO72_RS01230"
                     /old_locus_tag="DO72_1996"
     CDS             7155..7808
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603248.1"
                     /locus_tag="DO72_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1996"
                     /product="DUF1345 domain-containing protein"
                     /protein_id="WP_004529073.1"
                     /transl_table=11
                     /translation="MTFYPQVLRNRPRMVIAVAAGVALGLLFPYPLRPFARVLIGWDCT
                     IWLYLVLMWVRMVRAHHHKVREIAMREDENATMVLTIICFATVASIAAIVLELVSAKSV
                     GFRSGLGHYAVTGATMFGAWFLIPTIFTLHYARLYYLSPKEARAMAFPDRELEPDYWDF
                     LYFSFTIAVASQTADVSLRGRSIRRAALAQSILSFYFNMAVLGLSVNVAAGLLS"
     misc_feature    7224..7226
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7955..8416
                     /locus_tag="DO72_RS01235"
                     /old_locus_tag="DO72_1995"
     CDS             7955..8416
                     /NRPS_PKS="Domain: Polyketide_cyc2 (6-147). E-value:
                     5.8e-10. Score: 31.7. Matches aSDomain:
                     nrpspksdomains_DO72_RS01235_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010120211.1"
                     /locus_tag="DO72_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1995"
                     /product="SRPBCC family protein"
                     /protein_id="WP_004525102.1"
                     /transl_table=11
                     /translation="MNTSTDRIEKRIVLNAPRSRVWRALTNADEFGAWFRVDLAGQTFE
                     AGRCVEGRITYPGYEHLVLRMRIERIEPEHRFSYHWHPAAIDPAVDYAQETPTLVVFEL
                     ADVAGGTLLTVVESGFDKLPIERRAEAFRMNDGGWGEQMTNIAAHVDAR"
     aSDomain        7973..8395
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS01235_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.80E-10"
                     /label="DO72_RS01235_Polyketide_cyc2.1"
                     /locus_tag="DO72_RS01235"
                     /protein_end="147"
                     /protein_start="6"
                     /score="31.7"
                     /tool="antismash"
                     /translation="RIEKRIVLNAPRSRVWRALTNADEFGAWFRVDLAGQTFEAGRCVE
                     GRITYPGYEHLVLRMRIERIEPEHRFSYHWHPAAIDPAVDYAQETPTLVVFELADVAGG
                     TLLTVVESGFDKLPIERRAEAFRMNDGGWGEQMTNIA"
     gene            8400..8765
                     /locus_tag="DO72_RS01240"
                     /old_locus_tag="DO72_1994"
     CDS             8400..8765
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004544760.1"
                     /locus_tag="DO72_RS01240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1994"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_004525103.1"
                     /transl_table=11
                     /translation="MSTRAEGRTSRAPLKRAQLRDCAEVFAALGDETRLRIVAALCAGT
                     ALSIAQITAGTDITRQSVTQHLLVLAQAGLVHDVKVGRERRWSFDPARIDAARAALDAI
                     GRQWDQALLRLRQAVEG"
     misc_feature    8830..8845
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.81"
                     /tool="antismash"
     misc_feature    9086..9097
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.17"
                     /tool="antismash"
     gene            9141..9374
                     /locus_tag="DO72_RS44810"
     CDS             9141..9374
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009940991.1"
                     /locus_tag="DO72_RS44810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004525104.1"
                     /transl_table=11
                     /translation="MTSGRAARDPASRTHRVTICAGMPGRGLVRAFPRKTAEASPRRRA
                     VDRGDTGFRRTFHRRSMKRFGRHREHRVNGGR"
     misc_feature    complement(9537..9552)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            9669..9953
                     /locus_tag="DO72_RS44815"
     CDS             9669..9953
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529069.1"
                     /locus_tag="DO72_RS44815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004544618.1"
                     /transl_table=11
                     /translation="MDAATNDAHSRRRRAVRIEPASCAFASVARRVPRDPAPWAVRRRT
                     GGRYKKATSSLRESSKQSNDEGPVVVGGRTCSANAHAVPSGRLPVRNAA"
     gene            10001..11590
                     /locus_tag="DO72_RS01250"
                     /old_locus_tag="DO72_1993"
     CDS             10001..11590
                     /NRPS_PKS="Domain: AMP-binding (9-418). E-value: 1.7e-95.
                     Score: 311.9. Matches aSDomain:
                     nrpspksdomains_DO72_RS01250_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009978089.1"
                     /locus_tag="DO72_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1993"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_038741416.1"
                     /sec_met_domain="AMP-binding (E-value: 7.5e-106, bitscore:
                     351.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARHIVQAIQSHAFATPYKCALSDSRGDLGYADLDSFSTRFAMRL
                     QDLGCRPGDRVVMLASRRALLVAAIIGVFKAGCVHVPLDPRMPADRLRYILHDVAPTLV
                     IADEDLIDAIDHALPAAAPIVPVTELERLLDDADSPRLDALVQPLPLPPLDERAIAYCI
                     YTSGSTGRPKGVLINHRSIADFFEGTRAVYDVTAQSRCASFSPLNFDVYLMDMLFPLAQ
                     GASLYVHDDVNAPDLLFDAIRAHDVTHFSAWGMMLGLIAQAEEFESAPLPHLKTILTGT
                     DVPDVKTVQRWLRKNAGVQVINAYGPTEATCAATAHVIREIEPERRTLYPIGKPLEHVR
                     ALLVDEGGNRITAPGVPGELMIGGTQVMQGYWNLPEETAARLVRLDGVPFYRTGDVCAY
                     LADGSLYYMGRKDNEVKIGGYRIHLSEIQRVINSVPHVYGSEVVLLESRYGETLLAAGV
                     LLERGAPLDADCKADEIRQRLAAELPAYMVPRHVKVLEQFPQLSSGKTDRKALLSILQQ
                     RINESNQEEVNP"
     aSDomain        10028..11254
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS01250_AMP-binding.1"
                     /evalue="1.70E-95"
                     /label="DO72_RS01250_AMP-binding.1"
                     /locus_tag="DO72_RS01250"
                     /protein_end="418"
                     /protein_start="9"
                     /score="311.9"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="QSHAFATPYKCALSDSRGDLGYADLDSFSTRFAMRLQDLGCRPGD
                     RVVMLASRRALLVAAIIGVFKAGCVHVPLDPRMPADRLRYILHDVAPTLVIADEDLIDA
                     IDHALPAAAPIVPVTELERLLDDADSPRLDALVQPLPLPPLDERAIAYCIYTSGSTGRP
                     KGVLINHRSIADFFEGTRAVYDVTAQSRCASFSPLNFDVYLMDMLFPLAQGASLYVHDD
                     VNAPDLLFDAIRAHDVTHFSAWGMMLGLIAQAEEFESAPLPHLKTILTGTDVPDVKTVQ
                     RWLRKNAGVQVINAYGPTEATCAATAHVIREIEPERRTLYPIGKPLEHVRALLVDEGGN
                     RITAPGVPGELMIGGTQVMQGYWNLPEETAARLVRLDGVPFYRTGDVCAYLADGSLYYM
                     GRKDNEVKIG"
     CDS_motif       10214..10252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01250_0001"
                     /evalue="1.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="DO72_RS01250"
                     /protein_end="84"
                     /protein_start="71"
                     /score="12.5"
                     /tool="antismash"
                     /translation="GVFKAGCVHVPLD"
     CDS_motif       10478..10537
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01250_0002"
                     /evalue="3.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="DO72_RS01250"
                     /protein_end="179"
                     /protein_start="159"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYCIYTSGSTGRPKGVLINH"
     CDS_motif       11060..11143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01250_0003"
                     /evalue="5.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="DO72_RS01250"
                     /protein_end="381"
                     /protein_start="353"
                     /score="41.1"
                     /tool="antismash"
                     /translation="PGVPGELMIGGTQVMQGYWNLPEETAAR"
     CDS_motif       11219..11284
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01250_0004"
                     /evalue="2.80E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="DO72_RS01250"
                     /protein_end="428"
                     /protein_start="406"
                     /score="26.1"
                     /tool="antismash"
                     /translation="YMGRKDNEVKIGGYRIHLSEIQ"
     gene            11587..11847
                     /locus_tag="DO72_RS01255"
                     /old_locus_tag="DO72_1992"
     CDS             11587..11847
                     /NRPS_PKS="Domain: PCP (3-72). E-value: 2.6e-13. Score:
                     42.0. Matches aSDomain: nrpspksdomains_DO72_RS01255_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525106.1"
                     /locus_tag="DO72_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1992"
                     /product="acyl carrier protein"
                     /protein_id="WP_004525106.1"
                     /sec_met_domain="PP-binding (E-value: 8.8e-11, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTETMLIQILESVIGVKKVTGDTRFLDIGGNSLNLVEVLKQIKA
                     KTGVAPSPRLFFDKTRSTVAALSAEIDTLREMSSAAAPVAG"
     aSDomain        11596..11802
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS01255_PCP.1"
                     /evalue="2.60E-13"
                     /label="DO72_RS01255_PCP.1"
                     /locus_tag="DO72_RS01255"
                     /protein_end="72"
                     /protein_start="3"
                     /score="42.0"
                     /tool="antismash"
                     /translation="ETMLIQILESVIGVKKVTGDTRFLDIGGNSLNLVEVLKQIKAKTG
                     VAPSPRLFFDKTRSTVAALSAEID"
     gene            11944..12849
                     /locus_tag="DO72_RS01260"
                     /old_locus_tag="DO72_1991"
     CDS             11944..12849
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004533401.1"
                     /locus_tag="DO72_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1991"
                     /product="chlorinating enzyme"
                     /protein_id="WP_004525107.1"
                     /sec_met_domain="PhyH (E-value: 1.5e-35, bitscore: 120.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRFHLSEAEKKFFYENGYAGPFTLYEPEEMTRVWEEVRMDLLD
                     TAKAAFPNSKLNYDRHLDMLSLNQIISHPKIVDRISSILGPDVLSWRTEWFPKYPGDEG
                     TDWHQAESFVEFEGTEKLEPTAAEEGRPWELTAWIAMSEATKENGCLKLMPGSHRTWFF
                     DEKRNIPFEPENFNKRVLDDGQKSGFYGYDYEKLKLDPSWKPDEARAVHMEVKPGQFFI
                     FTSRCMHGSNPNTSKDSVRFGWATRFVPTHVKVYAGQDSFHHFGEVLPLDRYSTVLVAG
                     EDRYGHNRVTKPLAAVAALA"
     misc_feature    complement(11948..11959)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.79"
                     /tool="antismash"
     gene            12853..13650
                     /locus_tag="DO72_RS01265"
                     /old_locus_tag="DO72_1990"
     CDS             12853..13650
                     /NRPS_PKS="Domain: Thioesterase (27-252). E-value: 5.3e-49.
                     Score: 159.6. Matches aSDomain:
                     nrpspksdomains_DO72_RS01265_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009978083.1"
                     /locus_tag="DO72_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1990"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_004525108.1"
                     /sec_met_domain="Thioesterase (E-value: 9.7e-46, bitscore:
                     154.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHW
                     GEALPDDVELVAVQMPGRENRLNEPLLYSMDEAVPPLVDALAPLLDRPFAFFGHSTGAL
                     IGFEVARVLRARGYPQPRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPDAIL
                     QDPALLELLLPRIRADGAVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQ
                     HSFARYRFAGDHFFIHDEEASVLDHINRELEPLLSDASSTLIG"
     aSDomain        12934..13608
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS01265_Thioesterase.1"
                     /evalue="5.30E-49"
                     /label="DO72_RS01265_Thioesterase.1"
                     /locus_tag="DO72_RS01265"
                     /protein_end="252"
                     /protein_start="27"
                     /score="159.6"
                     /tool="antismash"
                     /translation="RLFCFHYAGSGGSIFRHWGEALPDDVELVAVQMPGRENRLNEPLL
                     YSMDEAVPPLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQPRLLIASAQNA
                     PDVKPEVIRHRLSDAEFVEVLRGCNGTPDAILQDPALLELLLPRIRADGAVFETYRYER
                     QAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDEEASVLDHIN
                     REL"
     CDS_motif       12937..12960
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01265_0001"
                     /evalue="1.30E-02"
                     /label="NRPS-beforete1"
                     /locus_tag="DO72_RS01265"
                     /protein_end="36"
                     /protein_start="28"
                     /score="8.7"
                     /tool="antismash"
                     /translation="LFCFHYAG"
     CDS_motif       13126..13191
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01265_0002"
                     /evalue="8.30E-06"
                     /label="NRPS-te1"
                     /locus_tag="DO72_RS01265"
                     /protein_end="113"
                     /protein_start="91"
                     /score="18.3"
                     /tool="antismash"
                     /translation="RPFAFFGHSTGALIGFEVARVL"
     CDS_motif       13444..13464
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01265_0003"
                     /evalue="3.80E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="DO72_RS01265"
                     /protein_end="204"
                     /protein_start="197"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="IVVFHGA"
     CDS_motif       13474..13491
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01265_0004"
                     /evalue="2.30E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="DO72_RS01265"
                     /protein_end="213"
                     /protein_start="207"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="LVHDAG"
     gene            13658..14341
                     /locus_tag="DO72_RS01270"
                     /old_locus_tag="DO72_1989"
     CDS             13658..14341
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006027931.1"
                     /locus_tag="DO72_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1989"
                     /product="RraA family protein"
                     /protein_id="WP_004525109.1"
                     /transl_table=11
                     /translation="MAQWNSDDELFALMRAELSTCPVSDVMEVLGFAYPMLPPEIRPLR
                     RDMVMIGRAMPVQDEPPVPHGGLKRYDAKPFGLLFESVEALRPGEVYIASGGPTAVARL
                     GDLLVTRARNLGAAGVVLHAHVRDANAILDLNLPAFAHGTYAYGLQGRHNVVDYRCSIT
                     VGHVRIRPGDLIFGDGDGVCVIPREAEREVITRAIAKNRLERKVRGAIAEGRSVVEAFN
                     QYNVM"
     gene            14356..15300
                     /locus_tag="DO72_RS01275"
                     /old_locus_tag="DO72_1988"
     CDS             14356..15300
                     /EC_number="2.6.1.42"
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (51-286). E-value: 1.5e-38.
                     Score: 124.8. Matches aSDomain:
                     nrpspksdomains_DO72_RS01275_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529067.1"
                     /locus_tag="DO72_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1988"
                     /product="branched-chain amino acid transaminase"
                     /protein_id="WP_004529067.1"
                     /transl_table=11
                     /translation="MKSSYVWKNGELVPWEHAQVHVMSHALHYGTSVFEGVRAYEIGEK
                     AAILCGREHFERLLFSCKVARIASPMSVGQWMEATVETLRANGQRSAYIRPLVYRGAGE
                     SLGLDARQCPAEALLITTPWGAYLGDEALQQGVDVQVSSWRRNGAGAASTLAKIGGQYV
                     NGQAIVMEAHENGMSEGIALDTNGFVSEGSGENVFLVYKNEIFTPSIGSSILSGITRHC
                     VIRIARDLGYTVTETSIPREMLYLADEIFFTGTAVEICPVRSVDRMPVGSGKRGAVTKA
                     IQDQYFGIVRGTHADKWNWLTPVAVPSRDGARA"
     misc_feature    complement(14373..14388)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     aSDomain        14509..15213
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS01275_Aminotran_4.1"
                     /evalue="1.50E-38"
                     /label="DO72_RS01275_Aminotran_4.1"
                     /locus_tag="DO72_RS01275"
                     /protein_end="286"
                     /protein_start="51"
                     /score="124.8"
                     /tool="antismash"
                     /translation="REHFERLLFSCKVARIASPMSVGQWMEATVETLRANGQRSAYIRP
                     LVYRGAGESLGLDARQCPAEALLITTPWGAYLGDEALQQGVDVQVSSWRRNGAGAASTL
                     AKIGGQYVNGQAIVMEAHENGMSEGIALDTNGFVSEGSGENVFLVYKNEIFTPSIGSSI
                     LSGITRHCVIRIARDLGYTVTETSIPREMLYLADEIFFTGTAVEICPVRSVDRMPVGSG
                     KRGAVTKAIQDQY"
     gene            15297..16139
                     /locus_tag="DO72_RS01280"
                     /old_locus_tag="DO72_1987"
     CDS             15297..16139
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Thioesterase (23-241). E-value: 1e-43.
                     Score: 142.4. Matches aSDomain:
                     nrpspksdomains_DO72_RS01280_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529066.1"
                     /locus_tag="DO72_RS01280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1987"
                     /product="thioesterase domain-containing protein"
                     /protein_id="WP_004529066.1"
                     /sec_met_domain="Thioesterase (E-value: 2.1e-43, bitscore:
                     146.5, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-08, bitscore:
                     32.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAREAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPGGL
                     PDWIEVVAVQLPGREYRLGEPLIEHAEPIVEALADIVPPLLDLPYAFFGHSMGALIAFD
                     LAHLLRARGFAQPLLFVASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIADP
                     ALRELWLPRLRADLTISATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAV
                     RYVGFSGGHFFMHGEEAGVLAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESGT"
     aSDomain        15366..16019
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DO72_RS01280_Thioesterase.1"
                     /evalue="1.00E-43"
                     /label="DO72_RS01280_Thioesterase.1"
                     /locus_tag="DO72_RS01280"
                     /protein_end="241"
                     /protein_start="23"
                     /score="142.4"
                     /tool="antismash"
                     /translation="RLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGREYRLGEPLI
                     EHAEPIVEALADIVPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLFVASGRSA
                     PRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIADPALRELWLPRLRADLTISATYRYV
                     GPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAGV"
     CDS_motif       15561..15623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DO72_RS01280_0001"
                     /evalue="1.00E-07"
                     /label="NRPS-te1"
                     /locus_tag="DO72_RS01280"
                     /protein_end="109"
                     /protein_start="88"
                     /score="24.4"
                     /tool="antismash"
                     /translation="PYAFFGHSMGALIAFDLAHLL"
     gene            16136..17029
                     /locus_tag="DO72_RS01285"
                     /old_locus_tag="DO72_1986"
     CDS             16136..17029
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529065.1"
                     /locus_tag="DO72_RS01285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1986"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_004529065.1"
                     /transl_table=11
                     /translation="MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSD
                     GLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPA
                     KVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSA
                     GIATRENIDEYMTTTEYALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRV
                     RASVADMVEKVREYVPGYRLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAAL
                     AVASHRHATARLGATQ"
     gene            17026..18069
                     /gene="dmpG"
                     /locus_tag="DO72_RS01290"
                     /old_locus_tag="DO72_1985"
     CDS             17026..18069
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899155.1"
                     /locus_tag="DO72_RS01290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1985"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_004525113.1"
                     /sec_met_domain="HMGL-like (E-value: 3.2e-49, bitscore:
                     165.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILISDATLRDGNHAIRHQLSAAQIHAYARAADEAGIDVVEVGHG
                     NGLGGSSCLLGQTPIGDRLMLETARAALRTSRLGVHFIPGLGKAADISLALEIGVDVVR
                     VATHCTEANVSARFIEQTRAAGRTAFGVLMMSHMAPPDALLAQAKLMERYGAQAVVLMD
                     SAGYSTPSLVRAKVERLVDGLDIDVGFHAHNNLGLAVANSLVALEAGARIVDACVKGFG
                     AGAGNTQLETLVAAMEREGHDTRTTFERVMTLARGTETFLNPKTPHIQPANIASGLYGL
                     FSGYVPHIQKAAQEFGVNEFELYKRLAERKLVAGQEDIIIEEASRLARERDVQRATGGV
                     RVRELSA"
     gene            18116..18529
                     /locus_tag="DO72_RS01295"
                     /old_locus_tag="DO72_1984"
     CDS             18116..18529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529064.1"
                     /locus_tag="DO72_RS01295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1984"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_195761040.1"
                     /transl_table=11
                     /translation="MNERGFGAWNRVERETLTERIERQVVSGDALTMARLYLKKGAFVG
                     THSHPNEQLTYILEGRLLFRYGKHLEHEVEVGPGEILHLPANVPHNALCLEDAVDLDVF
                     TPVRTDWLAPGGNRYFAGASAATSPTPVPSASR"
     gene            18567..19169
                     /locus_tag="DO72_RS01300"
                     /old_locus_tag="DO72_1983"
     CDS             18567..19169
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010120151.1"
                     /locus_tag="DO72_RS01300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1983"
                     /product="LysE family translocator"
                     /protein_id="WP_004525115.1"
                     /transl_table=11
                     /translation="MLIQDALLKMSFYVSLVLIVPGPTNTLLLSSGLKVGLRGTWHLVI
                     AEALGYVVAISLWGFFLLSVAASRPWLFGAIKLLSAAYILWLAVKMWTKSRALHELSAG
                     PISFGDLFVATLMNPKALLFASTMFPLEAFRSLSYFGWAVIVFLIVLAPIGVGWSSLGG
                     LLTSQRSWAAHTSTFMRCASLVLATFSGSLAYSVLGH"
     gene            complement(19236..20267)
                     /locus_tag="DO72_RS01305"
                     /old_locus_tag="DO72_1982"
     CDS             complement(19236..20267)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853670.1"
                     /locus_tag="DO72_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1982"
                     /product="autoinducer binding domain-containing protein"
                     /protein_id="WP_038791396.1"
                     /transl_table=11
                     /translation="MARNRTVLPLERAQVDVVQERSGVVGDRRISLRVCGEATQGYLLE
                     RYHAAPGEPSFVQRVNLFDDATIASFVEHDPYSAELKSLYRAVIDVPKKALKFAGRETI
                     QPEFASECVSESGLLTVMRNTILECGATNCFYHYFRIDEKTGNLKNHELLIGGTPVWPH
                     RYVHRHWYLNDPAMAHARNDTRPLRASTLAPLPHDHWLNQQAQFLGLTSNVFFPAHRRD
                     DDTIGLLHVSSSLPAAQGEEIIWRNRRTLRGLATEMLEWKVTAQRNTLAREMSLSHHEL
                     VALRLVGRGANARHVAEELKLQEHAVYQLFTSINKKMNSSHIRTSANKAKQFGFLAEGY
                     ISE"
     misc_feature    complement(19809..19811)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19914..19916)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20426..20441)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            complement(20450..20776)
                     /locus_tag="DO72_RS34025"
                     /old_locus_tag="DO72_1981"
     CDS             complement(20450..20776)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195671.1"
                     /locus_tag="DO72_RS34025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1981"
                     /product="hypothetical protein"
                     /protein_id="WP_161788996.1"
                     /transl_table=11
                     /translation="MPAAFAADRNGKNPHRPAPRACDMNAKAAALHIRRSRRSGNSFGP
                     AFNGCALNIPCRTSARGPHRFSESRYPFPNRAINQEFSDSIPAEFIGHQKFNYPKPITN
                     ITIN"
     gene            complement(21009..21863)
                     /locus_tag="DO72_RS01310"
                     /old_locus_tag="DO72_1979"
     CDS             complement(21009..21863)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525118.1"
                     /locus_tag="DO72_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1979"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_004529061.1"
                     /transl_table=11
                     /translation="MNDCARDIAPDRDQIRIGSGAPGIERVEAHFLDHAFTPHRHDTYA
                     IGITLSGLQTFGYLGEIHHCLPGQCHILHPDELHDGRAGTDEGFGYRIIYVDPALVQEA
                     LGGRMLPFVRSPIFQAPAVSEALAAGIWNLDEEIDNVSRIDIAVAVANLLTAAAAKGSA
                     PKAGPLAMVELTRIRDIIASCPREPISMDALEHASGLDRWTIARQFRRLFGTSPSRFRT
                     QRQLNLVRRLLMEGESLSTASTDAGFSDQSHMSRHFKSTYGITPGAWISAVRTRHAQHP
                     SDH"
     misc_feature    complement(21822..21835)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(21898..21907)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            21959..22552
                     /locus_tag="DO72_RS01315"
                     /old_locus_tag="DO72_1978"
     CDS             21959..22552
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009907291.1"
                     /locus_tag="DO72_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1978"
                     /product="LysE family translocator"
                     /protein_id="WP_004190802.1"
                     /transl_table=11
                     /translation="MRSLVALLFAAAVVMGSPGPSTVSATAMGASYGVRRSLKYAWGLI
                     AGTVAVLLLVSTGVTAFVMSMPSAARILNIVSALYILYLAYRIATAPPLDKRAENLSSP
                     AFKGGFLLAVANPKAYIAIGAVFAGTTLVATDYGLDAAAKIVLLSVMIVIIHLGWLLAG
                     VSLSRFLHDPVASRIINVSLAAILAIVSLIALFE"
     misc_feature    22517..22519
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(22794..23204)
                     /locus_tag="DO72_RS01320"
                     /old_locus_tag="DO72_1977"
     CDS             complement(22794..23204)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195676.1"
                     /locus_tag="DO72_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1977"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_004195676.1"
                     /transl_table=11
                     /translation="MDTKHDGGSPIAERRTEGFRLLESGMPQADVARRLVVSRQSVCRW
                     AKRLAERDGRIAKAPGRPRRLNSAQCATLRAMLDDGALAAGFASPQWTLARVRKLIERE
                     FGVAYSKTGGWELLRTLGVSLQRTERHPHIAR"
     gene            23457..24695
                     /locus_tag="DO72_RS01325"
                     /old_locus_tag="DO72_1976"
     CDS             23457..24695
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853665.1"
                     /locus_tag="DO72_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1976"
                     /product="alpha-hydroxy acid oxidase"
                     /protein_id="WP_024429600.1"
                     /transl_table=11
                     /translation="MANVGKAWNIDDLRKMARKRVPKYFFDYLDGGANSETTMRANEND
                     FARWRLRQKVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWSRGEIAAGRAADD
                     AGIGQCLSTFSICSLEDVAAARSGPLYFQLYMFRDRDLTEDILARCRLANVDAVFLTVD
                     TCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCAGALSHGVPRIGNVLRYPELGAS
                     LLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEGVDGILISNH
                     GGRQLDPAPSVMDVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAVSIGRAYVY
                     GLGAAGEKGVSRCLELLKGEMLPALNMMGFESVAELRAAGKSALRMAVPVHGATAVVEG
                     AEGGARRLTESVL"
     misc_feature    23488..23501
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.99"
                     /tool="antismash"
     misc_feature    complement(23489..23503)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.52"
                     /tool="antismash"
     gene            complement(24760..25215)
                     /locus_tag="DO72_RS01330"
                     /old_locus_tag="DO72_1975"
     CDS             complement(24760..25215)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010110174.1"
                     /locus_tag="DO72_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1975"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_004190434.1"
                     /transl_table=11
                     /translation="MSVESVRQFLAEKAPDIDVIALSESSSTMTLSAAWDIKPAQIAKT
                     LAMKVGDAHVLLVSCGDSRLDNQKIKAALGGKAKMLSAEETVAVTGHPVGGVCPFGLPA
                     PLPVYCDVMLKSYEFVVPAAGSTHAALRIDPVRLAELVEAEWVDVCK"
     gene            complement(25563..26276)
                     /locus_tag="DO72_RS01340"
                     /old_locus_tag="DO72_1974"
     CDS             complement(25563..26276)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019255914.1"
                     /locus_tag="DO72_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DO72_1974"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_038791398.1"
                     /transl_table=11
                     /translation="MSTPSAAAKFDPARAAQYAEQSRIALAGYDACHDLAACMLASAIP
                     AEAHAAQVLVAGAGGTAREIAALAGLAPGWRFTAVDPSRPMLDLANANIAAAGLDARVT
                     THLGYVDDLPADARFDGATLIGVLHHVAGDGAKAALLRSIARRLKPGAPLVVAGNYRRY
                     AEHPRLLSAWAQRWRMHGATPEEVARKLATILRGADPPASEDAVHALLDAAGFREPVRF
                     FASLFWGAWIAMRGA"
ORIGIN
        1 tcgaggcgat ggcggcgggg ctgcccgtcg tgaccgcgcg caccgcgggc ggcgcggaga
       61 tcatcacgcc ggagtgcggg atcgtgctcg acgatcccga cgatccggcc gcgctcgcgg
      121 ccgcgatcga gcgcctcgcg cgctcgcgcg acgcgtgccg cgcgatgggc gaggcggccc
      181 gcaggctgat ggagggattc ggatgggcgc gcatgggcgc gcagtacatc gcattgtatc
      241 ggcggctgcg ccagtcgtcg cagccgtcgc cgctcgccgg caccgagcat gtcgtgacgc
      301 aggagcggtc gtaatgaagc ataccgaaac gtcgatcaag tcgctgcaga tcggcatgca
      361 ctggtttccc gagcgagcgg gcgggctcga tcgcatgtat tactcgctcg ttggcgcgct
      421 gccgagcgcg ggcgtcgcgg tgcgcggcgt ggtcgcgggc tccgagcgcg tcgcggccga
      481 cacgggcggc gcgatccgcg gcttcgggcc ggcgacgtcg tcgttgccgc ggcggatgat
      541 cgccgcgcgc catgcgctgc gcgacgtgat gcgcatcgag cggcccgacg tcgtgtcgtc
      601 gcacttcgcg ctgtacacgt tccccgggct cgacgtgacg cgcggcattc cgcaggtgtc
      661 gcatttccag ggcccgtggg ccgacgagag ccacgtcgag ggcgcggatt cgctcgggca
      721 gaaggtcaag caccggctcg agcaggcggt ctatgcccgc tcgtcgcggc tcatcgtgct
      781 gtcgcacgcg ttcgggcaga ttctcacgtc gcgctacaac gtcgatccgg cgcgcgtgcg
      841 cgtcgtgccc ggctgcgtcg acaccgcgca attcgatctg ccgatgacgc ccgccgacgc
      901 gcgccgcaag ctgcaactgc cgcaggatcg gccgatcgtg ctcgcggtgc ggcggctcgt
      961 gcggcgcatg gggctcgagg atctgatcga cgcggtgaag accgtgcgcc gccggcatcc
     1021 ggacgtgctg ctgctgatcg ccggcaaggg gcggctcgaa ggcgagctgc gcaaacggat
     1081 cgacgacgcc gagctcggcg agaacgtgaa gctgctcggt ttcgtgcccg acaatcatct
     1141 ggccgcgctg taccgcgcgg cgacgctcag cgtcgtgccg accgtcgcgc tcgagggatt
     1201 cgggctcatc accgtcgagt cgctcgcgtc cggcacgccg gtgctcgtga cgcccgtcgg
     1261 cgggctgccg gaggcggtcg cgggcctgtc ggaggcgctc gtgctgccgg aggtgggcgc
     1321 ggccgcgatc gcggacgggt tggccgcggc gttgtccggc tcgctcgtgc tgccggatgc
     1381 ggacgcatgc cggcgatacg cgcgcgcgca tttcgacaac acggtgatcg cgcgccgcgt
     1441 cgcggaggtc tacgaggagg cgattcgggc cgccgtttga ccgatgcggc gggcacggcg
     1501 ggctcggtgt cccgcgaatc gcgtgcgggg cgccgggcct ggcgcgccgg gcggcgccgc
     1561 gcgctttcac gttacccgac ggcattgccg cgacgcgccc ggcccggcgc ggccgccccg
     1621 gtgcaacgtg cgaggcgcac gcgagcgtgc gaggcggtgg cgaatgcgag atggggcgct
     1681 ttcttcgagt cgtcgcgtcg ttgcatcgtc gcggcgttgg tgcttcacgt cgcgtgcgat
     1741 gtcggcccgc tcgcgcgcat cggaaagctc agtgccgatc gctgcgccag cggccgggcg
     1801 cgagcccgaa ccgtttcgtg aacgcgtgcg tgaacgcgct ctggtcggcg aatccgactt
     1861 cgctcgcgat gtcggtcagc gaatgtttcg gatccccgag caacatgacg gcggcgtcga
     1921 gccgcaaccg ctgcagatag cgatgcggcg tctcgccgaa cgcttcgcag aaaagctgat
     1981 ggaagcggcg catgccgaag ccgcaatgcg cggcgagatc ggcgatgcgc agcggctgcg
     2041 cgaggtgcgc gcgcagccag ccgtcgatgc gtgcgaagtc gagcccgacg gcgggctgcg
     2101 acggcgcgcc gcccagctcg ccgacgagcg cgccgcatag ccgcgcggcc gcttgccagt
     2161 gcaggcgccg ggccgaggcg gcatcggcga gcggcccgcg cgcgatgcgc gacgcgagtt
     2221 cgccgacgag cgtcgtgagg cccgggtcga tcgccatcgt cctggcgcgc tcgaacagcc
     2281 gctcgggcac cgcgagcgag ccgggcggca agtcgagcac cagttggctg ttgtcggcga
     2341 ggcccgcgta atcgtgccgc gcgccggccg gaatcagcca cgcgcagcgg cggtcgatcc
     2401 gctcgtcgac gccgtcgacc gtcatcgtca tcgcgccgtc gacgccgagc acgatctgat
     2461 ggaaatcgtg cacgtccgac gcctgcacgg cgccgtaacg gcgcagcgac aggctcgggg
     2521 cggcgaggcg ggtcatgatc gggcgggcgg cctgtgaacg cgcgcgacgg ggcgacgggc
     2581 ggcggggcgg cgccgggctc agacgtcgag cagttcgact tcgaacacga gcgtcgcatt
     2641 gggcggaatc acgccgcccg cgccgcgcgc gccgtagccg agttgcggcg ggatcgtcag
     2701 acggcgcacg ccgcccacct tcatcccttg cacgccttcg tcccacccct tgatgaccat
     2761 gccgccgccg agcacgaacg cgaacggatc attgcgatcc ttgctcgaat cgaacttctg
     2821 gccgtcggtg agccagcccg tgtagtgcac gctcaccgtc tggcccgcgc gcgcctcggc
     2881 gcccgagcct tcggtcaggt cttcgtattt gaggcccgat tcggtggtga cgactgtcat
     2941 gaaatgctcc tgaaggatcg aaatgacccg ctattgtagg ggagccgcgc gatctcgacc
     3001 ggatttcccg gcgcgccggt ttcgcggcgt cggccgatgc cgcgggaaaa cgctcggcga
     3061 tgggcgtttg caagacagac gccgatttgc gcgatcacgc cgaaacgccc gtcgcgcggg
     3121 gcttgcgggt tcgccgcgcg gcgcttgccg cgcgccgcgc gtttggaagg cggccactaa
     3181 cacgcgcctt gcttaacccc ggtccgtcgc catattgttt cagttattaa tgtaaaggtc
     3241 ggcggccagg ctgcgggcgc gagcggccgg cgctaggccg ggcggcgcct tctgcgcgcg
     3301 gtgcccgtgc aagcgcgacg gcgccgaaac gtcggaccgc gcgaacgccc ggtcggcatg
     3361 cgccgcaacc ggtttgcgtg ccgcgtgccg ctcgcgcgga ccttcgcgga cgttgcccgc
     3421 caccacccag acaggagaca tcgatgaatc aacccgcgaa gtcgacggac ccggtgtccg
     3481 tgatgcccgt gcgccgcgat ctgcgcttca acttgcccgt cgagcgcgcg acggattggc
     3541 acgggcaggg ctcgcaagtt tcgcacttct tcaacgcgct atcgcttctg tttccagcgg
     3601 gcgagcgctt tttcatggat tcggtgcgca actatcgcga ccggatcgac gatccggtgc
     3661 tgaagaaaca ggtgctcggc ttcatcggcc aggaggcgat gcacacgcgc gagcatgtcg
     3721 agtacaacga attgatgcac gcgaaccggc tgccggcgcg cacggtcgac aggcgcgtgt
     3781 ggaaagtcac gggctggatg aagaaggtgc tgccgcattc ggtgcagctc gcgcatacgg
     3841 tcgcagccga gcactatacg gcgatgctgg ccaactggct gctgagcgag cccgccgcgc
     3901 tcgccggttc gcacgaaggc tacaagcaga tgtggctgtg gcacgcgctc gaggaaaccg
     3961 agcacaaggc ggtgtcgttc gatgtctgga acacggtgat gaagcctggg ccgaagcgct
     4021 atctgattcg catcggcgtg tatttgctga cgacgatgac gttctggccg aacgtgttcc
     4081 tgatccattc gcaactgatt cgatgggacc gcaagtcgga caagagcgta cgcggcctct
     4141 ggcgcgtggt cagcctgctg tacggcccgc gtcacggcat gttcccggcg atcgcgcgcg
     4201 agtggctgag cttcttcagg ccggacttcc atccgtggga ttacgacaat catcatcatc
     4261 tcgcccgcgt cgacgccatt gtcgaggcga cgcaggcgcg cgaagcgcgg aagctggcgg
     4321 ccgtcgagct cgacggcgcg aagccggcgt aaacgacggc ggcgggcggc ggcgttcgcg
     4381 ccagtgccgc gtcgcctgac tgcggcgcgc cggacggtgc gtcgacgcgg acggagaggc
     4441 cggtcgcgca ggttgcgtgg cgcgccgcgc ggtgacggct tgcgtcggct cgtgtctgcg
     4501 gtcggccgat tcgccgcgcg cccccgcagc gggcatgggc gggcgtattc gctgccgcgc
     4561 ggccttgccg cggtgctcgc ttcccggtct cgcgatatcc gattctcgcc ggtttcccct
     4621 ccggccgttt cttgcccgat cgctttggcc cgtcttcgtg cgcacccgga acactgcaaa
     4681 gaatctgcca cgcatgcacc atccgttctc tgcgtcgcgg gcacatgccg atgcccggct
     4741 gccgagcgcg ttgcctttct cgcgtgcgca gtgacgggcg ggcgatgcgc cgttgccgcg
     4801 tatgcgcggg aaggtgggga ggcaattgcg cgatgagcgg ctggagtagc cgcaggcgtg
     4861 cgctagggaa ggcgggatgc catccgtgca ggggctgctg gcgttagctc ggacagttgc
     4921 gctcgaacgc cagcccgaaa accagctcgc caactcattt cacttcgacc ccatcaaaac
     4981 gattgcaatc cgcagcttat tcggatccgc cattattttt cttgcaaaga tcccgaaatg
     5041 gactaatctt gttagtagat tcatttcgag actaaccgcc atgtcccgtc ccgccctgaa
     5101 gccgttttcg acgccaccgg aggcgaccgt cgagcaaatg tcggcggccg gtctgcgcgc
     5161 atttttcaat atcgcgcgcg actggaatct gtcgaccgat gagcagctcg ttttgctggg
     5221 ctcgcccggc cgttcgacgt tcttcaaatg gaaggcgtcg ccgcaaaccg cgcgcctcac
     5281 gcacgatacg ctcgagcgcc tgtcgctcgt gctcggcatc tacaaggcgc tgcagatcct
     5341 gctgccgcag ccggccgcgg ccgattcgtg ggtcaagcgg ccgaacgacg ccgcgccgtt
     5401 caacggcaag cgcgcgctcg accggatgct cgccggcaac gtcagcgatc tcgtcgcggt
     5461 gcggcaatat ctcgacgcgg cgcgaggcgg atgggcgtga cctctccgga acggcagacg
     5521 aactggccca ccgcgtcgct cgactgggcg cccgcctatc gcgtgattcc cacgcgcttt
     5581 cccgcgatca acctgttcga ccgcgtcgca tcggccgagg atttcgacgc gctctatgca
     5641 ctcgaggcgc tgaccaacga ccgcgtgcgc accgaagtcg gcatgctcga tctcgtgccg
     5701 ccgcaggagc ggcgcttcgg gcccggctac gggccgatca tggccgcgtt cacgcacctg
     5761 aatccgaacg gcagccgttt ctcggacggc agctacggcg tgttctattg cgcccgcgcg
     5821 cgcaatacgg cgatcgcgga aacgcgttat cacacgtcgc tgtttctcgc cgcgacgaag
     5881 gagccgccga tgcgccagca gatgcgtctc tacacggtag tcgcgcaagg cgaggtcgcc
     5941 gacgtgcgcg cgtggcgcga gcgcgacccg gcgctgctcg atctcgtcga ttactcggcc
     6001 ggccaggcgc tcggccgcgc ggtgcgcgat gcgggcggcg caggtattgc gtacccgtcg
     6061 gtgcgggatc cgggcggcga gtgcctcgcc gcgttcagga cgacgttgct gcacgattgc
     6121 cgccacgccg cgtatctcga atacaactgg aacggcgcgg cgatcgatgc ggtgttcgaa
     6181 ctgaatcagg tcggctgagg cggcgtgcgg tttgcgccgc cgtcgcgctt gcgcgccgtc
     6241 tcgacgcagc gcgtcgggcg ccgggcgccg tgcgtcggct ccgtccggct tccgcgcgtc
     6301 acggcagcgg cacgtcggcg gcgccctggt ggcgcgcggc cgcaaccgac atcgaccagc
     6361 tttcgccgct cttcgcgtcg agcaacgtga gccggcccga cggatcgaac gcgcccgtat
     6421 cgacgaacgt ctgcgcgccg atgcgcacga catcatgcat cggcgtatgg ccgcagtaag
     6481 tggtcgacag cccggcctgc cgcgcggccg ggtcggtgcg cccgtacgcc agctcgcggc
     6541 cccacagcag ccgcgtgatc acgtcgggcg cgtagtcgcc gcggtcgagg tcggcgtcgc
     6601 tgccgaagaa ctccgcgtgc agcacgttga agcgcgcgtc gccttcgccg acgacgcgca
     6661 cgaggggcaa ctcgcgcagc cgccgcgcat ggcgcgcgag cgtcgcggcc ggcaggtcgg
     6721 ccgcccattc gccgccgatg cgctgccaca cgctcatcgg cagcttgccg tccgcgaccg
     6781 agcacagcac gtcttcgtgg ttgccgagca cgcaatgaaa ccacggtcgc tcgagcagcg
     6841 cgagcgccgc ttccgattgc gcgccgcggt cgacgaggtc gcccaccgag aacagccggt
     6901 cgcgtgccgg atcgaagcgc acggtgtgca gcagcgcgcg cagcggatcg acgcaaccgt
     6961 gcagatcgcc gacgacgaaa tcgcggccgg cgtggttcgc ggtatggcga cggatcaggg
     7021 gagcagtgtc cattcgccca tcttaggaca cagccgggct tggcgcagcg ggagaacgtg
     7081 acgataatcg ctgcgacgcg ccgcaacagc ggcgcgttct ttcacccgac tttcgatcgt
     7141 ttcggcgagt gaccatgacg ttctatccgc aagtgctgcg caatcgcccg cgcatggtga
     7201 tcgcggtcgc cgccggcgtc gcgttaggcc tgctgtttcc gtatccgctg cggccgttcg
     7261 cgcgcgtgct gatcggctgg gattgcacga tctggctgta tctcgtgctg atgtgggtga
     7321 ggatggtgcg cgcgcatcat cacaaggtgc gcgagatcgc gatgcgcgaa gacgagaacg
     7381 cgacgatggt gctgaccatc atctgttttg caacggtcgc gagcatcgcg gcgatcgtgc
     7441 tcgaactcgt cagcgcgaag agcgtcgggt tccgttccgg cctcggccac tacgcggtga
     7501 cgggcgcgac gatgttcggc gcatggttcc tgattccgac gatcttcacg ctgcactatg
     7561 cgcggctcta ctatctgtcg ccgaaggagg cgcgcgcgat ggcgtttccc gatcgcgagc
     7621 tcgagcccga ttactgggat ttcctgtact tctcgttcac gatcgcggtc gcgtcgcaga
     7681 cggcggacgt atcgctgcgc gggcgctcga tccggcgcgc ggcgctcgcg cagtcgatcc
     7741 tgtccttcta tttcaacatg gcggtgctgg ggctgtcggt caacgtggcg gcgggcctgc
     7801 tgagctgagc gcgaatgcgc gaagcttgcg tggcgcgaca tttgtctcgc gcgacgcgcg
     7861 ggcggcgcga gccggcgcgc gcgacgcccg cacatgcagg catttgcttg cctttcacgg
     7921 acgcgctgtc taatatgcag ccaggaggct gcatatgaac acatcgaccg atcgtatcga
     7981 aaagcggatc gtgctgaacg cgccgcgctc gcgcgtgtgg cgcgcgctga cgaacgccga
     8041 cgaattcggc gcgtggtttc gcgtcgatct ggcagggcag acgttcgaag cggggcggtg
     8101 cgtcgaaggc cgcatcacgt atcccggcta tgagcatctg gtgttgcgga tgcgcatcga
     8161 gcggatcgag ccggaacatc gcttctcgta ccactggcac cccgctgcga tcgatccggc
     8221 cgtcgactac gcgcaggaga cgccgacgct cgtcgtgttc gagctggccg acgtcgctgg
     8281 cggcacgctg ctcaccgtcg tcgaatcggg cttcgacaag ctgccgatcg agcgccgtgc
     8341 cgaagcgttc cgaatgaacg acggcggttg gggcgagcag atgacgaaca tcgccgccca
     8401 tgtcgacgcg cgctgagggc cggacatcgc gcgcgccgct caagcgcgcg caactgcgcg
     8461 attgcgcgga ggtgttcgcc gcgctcggcg acgaaacgcg gctgcggatc gtcgccgcgc
     8521 tgtgtgccgg cacggcgctg tcgatcgcgc aaatcaccgc gggcaccgac atcacgcgcc
     8581 agtcggtcac gcagcatctg ctcgtgctcg cgcaagcggg gctcgtgcac gacgtgaaag
     8641 tcgggcgcga gcggcgctgg agcttcgatc ccgcgcggat cgatgcggcg cgcgcggcgc
     8701 tcgatgcgat cggccggcag tgggatcagg cattgttgcg gctgcggcag gccgtcgaag
     8761 gatgacggcg gcgtgaccgc gtcgtcttcg gaggcaggcg cggttggctc cgctggccga
     8821 tacgttcggt tgaccgaatg atccgccgcg cgcgagccgg cgccgcgggc gaatgcgcgc
     8881 ggcgctcgcc agtgccggcg agcgccgcgc attcggcgat agggcccgcg ccgtgttgca
     8941 tgcacgtcaa gcgcgctgga ggcgttacgc ggcgcgccgg tgcgcagccg cagccgatac
     9001 ttggtggccg gcatcgcgcc tgcgcgcgcg cctgccgtgc cgtcgacaac atcgcacgca
     9061 ttgccgtcgg gcgacgttgc gcaccgaaat cgctttttcg cggcgggctt cgccgaatcc
     9121 atacaaaccg atcctgtttc gtgacgagcg gccgcgccgc gcgcgatccc gcatcgcgca
     9181 cgcatcgggt cacgatttgc gcgggcatgc cggggagagg gctcgtacgc gcttttccgc
     9241 gcaagacggc cgaagcgtcg ccgcgcagac gcgcggttga ccgcggcgac acgggatttc
     9301 gccgcacctt tcatcgtcga tcgatgaaac gcttcgggcg gcatcgcgag caccgcgtga
     9361 acggtggccg ttaaagcgac gaatgtcctc gatttgcctc gatagccaat tcggctgcgt
     9421 tcagagcgga tatgacgccg cgtgatacga ccttgcacct gtcgtaatac ggatatgacc
     9481 cgcgcaacta cgtggcgccg acgtacttat tgggtcaccg aaaaataatt gcgcgaccaa
     9541 ataaatatca attaaacact taaattttca ttacggtgct tattcttcat ttccggtgaa
     9601 atcgcgggca tatattccgg aagtgatcta agtatttcct cggagaattt catctagcct
     9661 atcaatcaat ggatgcggcg acgaacgacg cgcattccag acgacgccgc gccgtacgta
     9721 tcgagcctgc ctcgtgtgcg ttcgcgagcg ttgcgcgccg ggtgccgcgc gatcccgctc
     9781 catgggcggt tcggcggcgt accggcgggc gatacaaaaa agcaaccagc agtctgagag
     9841 aaagcagcaa gcagtcaaac gacgaggggc cggtagtcgt tggcggacga acgtgcagcg
     9901 cgaacgcgca tgccgtgccg tccggccgtc tgccggtgcg caatgccgcc tgaatctcga
     9961 aggtgcccgt aaagagacat cgcaaagagg attcagtcag atggccagac acatcgttca
    10021 agcaatccag tctcacgcgt tcgcgacgcc gtacaaatgc gcgttgtccg attcccgcgg
    10081 cgatctcggc tacgccgatc tcgacagctt cagcacgcgt tttgcgatgc gcctgcagga
    10141 tctgggctgt cgccccggcg atcgcgtcgt gatgctcgcg agccgccgcg cgctgcttgt
    10201 cgcggcgatc atcggcgtgt tcaaggcagg ctgcgtgcat gtgccgctcg atccgcgcat
    10261 gccggccgac cgtcttcgct acatcctgca cgacgtcgcg ccgacgctcg tgatcgccga
    10321 cgaggatctg atcgatgcga tcgatcacgc gctaccggcc gccgcgccga tcgtgcccgt
    10381 gaccgaactc gagcggcttc tagacgacgc cgattcgccg cggctcgacg cgctcgtgca
    10441 gccgctaccg ctgccgccgc tcgacgagcg agcgatcgcg tactgcatct acacgtcggg
    10501 ctcgaccggc cgcccgaaag gcgtgctgat caatcatcgc agcatcgcgg atttcttcga
    10561 gggcacgcgc gccgtctacg atgtcacggc gcaatcgcgc tgcgcgagct tctcgccgct
    10621 gaacttcgac gtgtacctga tggacatgct gtttccgctc gcgcagggcg cgtcgctata
    10681 cgtgcacgac gacgtgaacg cgcccgatct gctgttcgac gcgattcgcg cgcacgacgt
    10741 cacccacttt tccgcgtggg gaatgatgct cggcctgatt gcgcaagctg aggaattcga
    10801 atccgcgccg ctgccgcatc tgaagacgat cctcaccggc accgacgtgc ccgacgtgaa
    10861 gacggtccag cgctggctca ggaagaacgc gggcgtgcag gtgatcaacg cctacgggcc
    10921 gaccgaagcc acctgcgcgg cgaccgcgca cgtgatccgc gagatcgagc cggagcggcg
    10981 cacgctctac ccgatcggca agccgctcga gcacgtgcgg gcgctgctcg tcgacgaggg
    11041 cggcaaccga atcacggcgc cgggcgtgcc gggcgagttg atgatcggcg gcacgcaggt
    11101 aatgcagggc tactggaatc tgccggaaga aacggcggcg cggctcgtgc gtctcgacgg
    11161 cgtgccgttc tatcgaacgg gcgacgtctg cgcgtatctc gccgacggca gcctctacta
    11221 catgggccgc aaggataacg aagtgaagat cggcggctac cggatccatt tgagcgaaat
    11281 ccagcgggtc atcaacagcg tgccgcacgt gtacggatcg gaggtggtgc tgctcgaatc
    11341 gcgctacggc gagacgctgc tcgccgccgg cgtgctgctc gaacgcggcg cgccgctcga
    11401 cgccgattgc aaggccgacg aaatcaggca gcgcctcgcg gcggagctgc ccgcctacat
    11461 ggtgccccgc cacgtcaagg ttctcgagca gtttccgcag ttgtcatcgg gaaagacgga
    11521 tcgcaaagcg cttctgtcga tattgcaaca gcgcatcaac gaaagtaacc aggaggaagt
    11581 gaatccatga aaaccgaaac gatgttgatt cagattctgg agagcgtgat cggcgtcaag
    11641 aaggtgaccg gcgatacccg ttttctggac atcggcggca attcgctcaa tctcgtcgaa
    11701 gtgctcaagc agatcaaggc gaaaacgggc gtcgcgccgt cgccgagact gtttttcgac
    11761 aagacgcgct cgacggtcgc ggcgttgagc gccgagatcg atacgctgcg cgaaatgagc
    11821 agcgccgcgg ctccggtcgc gggctgatcc cgcggggcat tgcaagagcc gcgcgagcgg
    11881 cggccgcgac aagcggaatc ttttcaggac atggctcttt acgccatatt taggagaact
    11941 gatatgcaaa agcgttttca tctgtcggaa gccgagaaga aattcttcta cgagaacggc
    12001 tatgccggcc cgttcacgct gtacgagccg gaggagatga cccgcgtctg ggaagaagtg
    12061 cggatggacc tgctcgacac ggcgaaggcg gcgtttccga acagcaagct caactacgac
    12121 cgccatctcg acatgctttc gctgaaccag atcatcagcc atccgaagat cgtcgaccgg
    12181 atctcgagca tcctcgggcc ggacgtgctg agctggcgca ccgagtggtt cccgaaatat
    12241 ccgggcgacg aaggcaccga ctggcaccag gccgaaagct tcgtcgagtt cgaaggcacc
    12301 gagaagctcg agccgacggc cgcagaagaa gggcggccgt gggagctgac cgcgtggatc
    12361 gcgatgagcg aggcgacgaa ggagaacggc tgcctgaagc tgatgccggg cagccatcgc
    12421 acctggttct tcgacgagaa gcgcaacatc ccgttcgagc cggagaattt caacaagcgc
    12481 gtgctcgacg acggccagaa atcgggcttc tacggctacg actacgaaaa gctgaagctc
    12541 gatccgagct ggaagccgga tgaagcgcgc gcggtgcaca tggaggtgaa gcccggccag
    12601 ttcttcatct tcacgtcgcg ctgcatgcac ggctcgaacc cgaacacgag taaggactcg
    12661 gtgcgcttcg gctgggcaac gcgcttcgtg ccgacgcacg tgaaggtcta cgcggggcag
    12721 gactcgttcc accacttcgg cgaagtgctg ccgctcgacc gttactcgac ggtgctggtg
    12781 gcgggcgagg accgctacgg ccataaccgc gtgaccaagc cgctcgccgc cgtcgcggcg
    12841 ctcgcgtaag cgatggacgg cgccgacatg aatgcatgcg aggcccgctg gttcctgttc
    12901 ggcgccgacg aacggaaacc cgatgcgcga atccggctgt tctgctttca ctacgcgggt
    12961 agcggcggct cgatcttccg ccactggggc gaggcgctgc cggacgatgt cgagctcgtc
    13021 gcggtgcaga tgccgggccg ggagaaccgg ctgaacgagc cgctgctgta ttcgatggac
    13081 gaggccgtgc cgccgctcgt cgacgcgctc gcgccgttgc tcgaccgccc gttcgcgttc
    13141 ttcgggcaca gcacgggcgc gctgatcggc ttcgaggtcg cgcgggtgct gcgcgcacgc
    13201 ggctatccgc agccgcgctt gctgatcgcg tccgcgcaga acgcgcccga cgtgaagccg
    13261 gaggtgattc ggcatcgatt gtcggatgcg gagttcgtcg aagtgctgcg cggttgcaac
    13321 ggtacgcccg acgcgatcct gcaggacccg gcactgctcg agctgctgct gccgcgaatc
    13381 cgcgcggacg gcgcggtgtt cgagacgtat cggtacgagc ggcaagcgcc gctcgattgc
    13441 cggatcgtcg tctttcacgg cgccgccgac gcgctcgtgc acgacgcggg gctcgcccgc
    13501 tgggcgggcg agacgcagca cagcttcgcg cggtaccggt ttgccggcga tcacttcttc
    13561 attcacgacg aagaggcgtc ggtgctcgac cacatcaacc gcgagctcga gccgcttttg
    13621 agcgacgcga gctccactct aatcggatga cagacaaatg gcgcagtgga attcggatga
    13681 cgagctgttc gcgctgatgc gcgccgagct ctcgacctgt cccgtcagcg acgtgatgga
    13741 ggtgctcggg tttgcctacc cgatgctgcc gccggagatc cggccgttgc ggcgggacat
    13801 ggtgatgatc ggccgcgcga tgccggtgca ggacgagccg cccgtgccgc acggcggcct
    13861 caagcgctac gacgcgaagc cgttcggact gctgttcgaa tcggtcgagg cgctgcgccc
    13921 aggcgaagtc tacatcgcga gcggcggccc gacggcggtt gcgcggctcg gcgacctgct
    13981 cgtcacgcgc gcgcgcaatc tgggcgcggc gggcgtcgtg ctccacgcgc acgtccgcga
    14041 cgcgaacgcg attctcgacc tgaacctgcc ggcgttcgcg cacggtacgt atgcgtacgg
    14101 gctgcagggc cgccacaacg tcgtcgacta tcgctgctcg atcaccgtcg gtcacgtgcg
    14161 aattcgtccg ggcgatctga ttttcggcga cggcgacggg gtctgcgtga ttccgcgcga
    14221 ggcggagcgg gaggtgatca cgcgcgcgat cgcgaagaac cggctcgagc gcaaggtacg
    14281 cggcgcgatc gcagaggggc gcagcgtcgt cgaggcattc aatcagtaca acgtcatgtg
    14341 aggagcgcaa caacgatgaa atcgagctac gtgtggaaga acggtgaact ggtgccgtgg
    14401 gagcatgcgc aggtgcatgt gatgagccat gcgctgcatt acgggacgag tgtgttcgaa
    14461 ggcgtgcgcg cgtacgagat cggcgagaag gcggcgatcc tctgcggccg tgagcacttc
    14521 gagcgcctgc tgttcagctg caaggtcgcg cggattgcgt cgccgatgag cgtcgggcaa
    14581 tggatggagg cgacggtcga gacgctgcgc gcgaacggtc agcgcagcgc gtacatccgg
    14641 ccgctcgtct atcgcggcgc gggcgaatcg ctcgggctcg acgcgcgaca gtgcccggcc
    14701 gaggcgctgc tcatcaccac accgtggggc gcgtatctcg gcgacgaggc gttgcagcaa
    14761 ggcgtcgacg tgcaggtgag cagctggcgg cgcaacggcg cgggagcggc aagcacgctg
    14821 gcgaagatcg gcggccagta cgtcaacggt caggcgatcg tgatggaggc gcacgagaac
    14881 gggatgagcg aaggtatcgc gctcgatacg aacggtttcg tcagcgaagg cagcggcgag
    14941 aacgtgttcc ttgtctacaa gaacgaaatc ttcacgccgt cgatcggcag cagcatcctg
    15001 agcggcatca cgcgccactg cgtgatccgg atcgcgcgcg atctcggcta caccgtgacc
    15061 gaaacgagca ttccgcgcga aatgctctac ctcgccgacg aaatcttctt cacgggcacc
    15121 gccgtcgaga tttgtcccgt tcgctcggtc gaccggatgc cggtcggcag cggcaagcgc
    15181 ggcgcggtga cgaaggcgat ccaggatcag tacttcggca tcgtgcgcgg cacgcacgcg
    15241 gacaaatgga actggcttac gcccgtggcg gtgccgtcgc gcgacggagc acgggcatga
    15301 gcgcgcgcga agccgcagcc gaatcgcctt ggctgatcgt ccatgaggcg cgcaacgcgc
    15361 gcgtgcggct cttctgcttt cactacgcgg gcgcgaccgc gtcgatcttc cgaacctggc
    15421 cgggcggcct gccggattgg atcgaagtcg tcgcggtgca attgccgggc cgcgagtatc
    15481 ggctcggcga gccgctgatc gagcacgcgg agccgatcgt cgaggcgctc gcggatatcg
    15541 tgccgccgct gctcgatctg ccgtacgcat tcttcggtca cagcatgggc gcgctgatcg
    15601 cattcgatct cgcgcacctg ctgcgcgcgc gcggcttcgc gcagccgttg ctgttcgtcg
    15661 catcggggcg cagcgcgccg cgcttcaggt ggcgggatgc gggcattcag acgctgcccg
    15721 acgaggcgtt catcgccgcg gtgcgcgact acaacggcac gccggaagcg ctgatcgccg
    15781 atcccgcgct gcgcgagctg tggctgccga ggctgcgcgc ggatctgacg atttcggcga
    15841 cataccgcta cgtcgggccg ccgccgctcg attgcccgat gctggtgttg cacggctcga
    15901 acgacggcct cgtcagcgac gccggtttgt ccggctggct cgccgagacg atcggggccg
    15961 tgcgctatgt cggcttttcc ggcggccatt tctttatgca cggcgaggaa gcaggtgtgc
    16021 tcgccgaggt tcgccgcgag ctcgagcgcg tgctcgcgcg cgccgcgcag gacgagccga
    16081 acggcatgcg cgagccggcg gcgcgcatga gtcatttgac ggaggagagc ggaacatgaa
    16141 gagcaagtca tcgcgcacgc gggtggcgat cctgggctcg ggcagcatcg ggctcgatct
    16201 gatgttcaaa gtcaaggcat ccgagcaatt cgatctgaag ttcgtcgtcg gacgcaatgc
    16261 gaacagcgac gggctgcggc tcgcgcgcag ttgcaacgtg gagacatcga gcgacggtct
    16321 cgatttcctg aaggcgcacg aggatgcgta cgacctcgtg ttcgacgcga catcggccgc
    16381 cgcgcacaag gtcaacaacc gcttcttctc cgacgcgggc aagttcgtga tcgatctgac
    16441 gcccgcgaag gtcggccgcc tgtgcgtgcc gtgcatcaat ctggacgaca tgggcgccga
    16501 gcagaacgtg aacctgatca cctgcggcgg gcaggcgagc ctgccgctcg cgtacgcgct
    16561 gaagcaggcg gtcgacgaga tcgattacct ggaggtggtg tcggcgatcg cgtcgcgcag
    16621 cgccggcatc gcgacgcgcg agaacatcga cgaatacatg acgacgaccg agtacgcgct
    16681 cgcgaaattc agcggtgcga agaagacgaa ggcgatcctc aacatcaatc cggccgagcc
    16741 cggtgtgcgg atgcagacga cgctctatgc gtacgcgcgc tatcgcgatt tcgaccgcgt
    16801 gcgcgcaagc gttgccgaca tggtcgagaa ggtgcgcgaa tacgtgcccg gctatcggct
    16861 cgtcgtcgag ccgctcgaaa gccaggggag gatcacgatc ggtctcaccg tgcgcgggcg
    16921 cggcgactat ctgcccgagt acgcgggcaa tctggacatc atcaactgcg cggcgctcgc
    16981 ggtcgcctcg catcggcacg caaccgccag actaggagcc acacaatgat actgatcagc
    17041 gatgcgacct tgcgcgacgg caaccatgcg attcgtcacc aactgagcgc cgcgcagata
    17101 catgcgtatg cgcgcgcggc cgacgaagcc ggcatcgatg tcgtcgaagt cggccacggc
    17161 aatggtctcg gaggctcgtc ttgcctgctc gggcagacgc cgatcggcga tcgcctgatg
    17221 ctcgagaccg cgcgcgccgc gctgcgcacg agccggctcg gcgtgcattt cattccgggg
    17281 ctcggcaagg cggcggacat ctcgcttgcg ctcgagatcg gcgtcgatgt cgtgcgcgtc
    17341 gcgacgcatt gcaccgaggc gaacgtgtcg gcgcgcttca tcgagcagac ccgggcggcc
    17401 ggacgcacgg cgttcggcgt gctgatgatg tcgcacatgg cgccgcccga tgcgctgctc
    17461 gcgcaggcga agctgatgga gcgctacggc gcgcaggcag tggtgctgat ggacagcgcc
    17521 gggtattcga cgccgtcgct cgtgcgcgcg aaggtcgagc gcctcgtcga cggtctcgac
    17581 atcgacgtcg gctttcacgc gcacaacaac ctcgggctcg cggtcgcgaa cagcctcgtc
    17641 gcgctcgaag cgggggcgcg catcgtcgac gcatgcgtga aaggcttcgg ggccggcgcg
    17701 ggcaatacgc agctcgaaac gctcgtcgcc gcgatggagc gcgaagggca cgacacgcgc
    17761 acgacgttcg agcgcgtgat gacgctcgcg cgcggcacgg agacgtttct caatccgaag
    17821 acgccgcaca tccagccggc gaacatcgcg agcgggctgt acggcctttt ctccggctac
    17881 gtgccgcata tccagaaagc cgcgcaggaa ttcggcgtca acgaattcga gctgtacaag
    17941 cggcttgcgg agcgcaagct cgtcgccggg caggaggaca tcatcatcga agaggcaagc
    18001 cgtctcgcgc gcgaacggga tgtgcagcgc gcaacgggcg gcgtgcgcgt tcgcgagctg
    18061 tccgcgtgag cgcgcgcctt tcacacgatc gagcgaggag gaaatcgtga caggtttgaa
    18121 tgaacgaggc tttggcgcat ggaatcgggt cgagcgcgaa acgctgaccg agcggatcga
    18181 gcggcaggtc gtctcgggcg acgcgctgac gatggcgagg ctgtatctga agaaaggcgc
    18241 gttcgtcggg acgcactcgc atccgaacga gcagctcacc tacatcctcg aggggcgcct
    18301 gctgtttcgt tacggcaagc atctcgagca cgaggtcgag gtcgggccgg gggagatcct
    18361 gcatctcccg gcgaacgtgc cgcacaacgc gctgtgcctc gaagacgcgg tcgatctcga
    18421 cgtgttcacg ccggtgcgga cggactggct cgcgcccggc ggcaaccgct atttcgccgg
    18481 cgcgtcggcc gcgacgtcgc ccacgccggt tccgtcggcg agccgatgac taccgtttac
    18541 cgaagccgac gaaccgagga ggcgccgtgc tcattcagga tgcgttgctc aagatgtcgt
    18601 tttacgtgtc gctcgtgctg atcgtacctg ggccgacgaa cacgttgctg ctgtcgtcgg
    18661 gcctgaaggt cggcctgcgc ggcacctggc acctcgtgat cgccgaggcg ctgggctatg
    18721 tcgtcgcgat ctcgctatgg ggcttcttcc tgctctccgt ggcggcgagc cggccctggc
    18781 tcttcggcgc gatcaagctg ttgagcgccg cgtacatcct ctggctcgcg gtcaagatgt
    18841 ggacgaagag ccgcgcgctt cacgagctgt ccgcggggcc gatcagcttc ggcgatctgt
    18901 tcgtcgccac gctgatgaac ccgaaagcac tgctgttcgc gagcacgatg ttcccgctcg
    18961 aggcgttccg ctcgctcagc tacttcgggt gggcggttat cgtgttcctg atcgtgctcg
    19021 cgccgatcgg cgtcggctgg tcgagcctcg gcgggctgct gacgtcgcag cgatcgtggg
    19081 ccgcgcatac gtcgacgttc atgcgttgcg cgtcgctcgt gctcgcgacg ttttcggggt
    19141 cgcttgccta ttcggtgttg gggcactgaa gccgttcgcg ggccgcccgc ccgcgagacg
    19201 gaccgagccg gcggggcgcc gcgcatggcg ctccgttatt ccgagatgta cccttccgcc
    19261 agaaagccga actgcttcgc cttgttcgcg ctcgtcctga tgtggctgct gttcatcttc
    19321 ttgttgatcg acgtgaacag ctgatagacc gcatgctcct gcagcttcag ttcctcggcg
    19381 acgtggcgcg cgttggcccc cctgccgacg agtcgcagcg cgacgagctc gtgatggctg
    19441 agcgacatct cgcgggcaag cgtgttgcgc tgcgccgtga ctttccattc gagcatctcg
    19501 gtggcgaggc cgcgcagcgt gcgccggttg cgccagatga tttcctcgcc ttgcgcggcg
    19561 ggcagcgacg agctcacgtg caacaaaccg atcgtgtcgt cgtcgcgacg atgcgcaggg
    19621 aaaaacacat tgctggtcag gccgagaaat tgcgcctgct ggttcagcca gtgatcgtgc
    19681 ggcagcgggg cgagcgtcga tgcgcgcagc gggcgcgtat cgttgcgcgc gtgcgccatc
    19741 gcgggatcat tcagatacca atggcgatgc acataacggt gcggccatac gggcgttccg
    19801 ccgatcaata attcgtgatt cttcagattt ccggttttct cgtctatcct gaagtaatgg
    19861 taaaaacagt tcgttgcgcc acattccagt atcgtattgc gcatcacggt caataaaccg
    19921 ctctcgctca cgcattccga tgcgaattcg ggttgaatcg tttcgcgtcc agcgaatttc
    19981 aatgcttttt tcggcacgtc tatgaccgca cggtacaagc ttttcagttc cgcggaataa
    20041 ggatcgtgtt cgacgaacga tgcaatggtc gcgtcgtcga acagattcac gcgttggacg
    20101 aacgaaggct cgcccggtgc cgcatggtat cgctctagca aatatccctg agtcgcctct
    20161 ccgcacaccc tgagcgatat tcgcctatcg ccgacgacgc cgctgcgttc ctgcaccacg
    20221 tccacttgcg cgcgttcgag aggcaacact gtacgatttc gagccatacg cgccaagcca
    20281 tgcttcgggg actgccggat ttcatgacga atcgccgcga ccaaacggag cgccgggccg
    20341 atggggaaag gcccgccaac aaatcgttcg cggtgcgcgg ggcggatgca tgcgttggaa
    20401 taggtccttt aaattactgc gtccatatat tgattggcaa tacaaacttt taattgatcg
    20461 tgatgtttgt gatgggtttt ggataattga atttttggtg gccaataaat tcggcgggga
    20521 tcgaatcgga aaactcctgg ttgatcgctc gattcggaaa gggatatcgc gattcgctaa
    20581 agcgatgcgg gccgcgcgcg ctcgtccggc aggggatgtt gagcgcacaa ccattgaagg
    20641 ccgggccgaa gctgtttccc gagcggcgcg agcgccggat gtgaagggcc gctgctttcg
    20701 cgttcatgtc gcaagcgcgc ggagccggac ggtgtgggtt tttgccgttg cgatccgccg
    20761 cgaacgcggc gggcatccgg gcgacggata tcgaatgacg ggcggttcgc aaagaatggc
    20821 ctcacgggtt ggttcattcg aagccgggca ggcatgcggc cggcggcgtg cggggtgtcg
    20881 ggcgcggccg gatgggccgc gtatgcgcgc gagcgctggg acggaacgcc atatccgcct
    20941 gttgggcggg cacggcgatc gaaagaaagc ggcgcgaggg tgtttcgccg ccgtccggtc
    21001 ggacgtgttt agtggtccga cgggtgctgc gcgtgccggg tgcgcacggc ggaaatccac
    21061 gcacccggcg tgatgccgta agtactcttg aagtgccgcg acatgtggct ctgatcggaa
    21121 aagcccgcgt cggtggaggc ggtcgacagc gattcgcctt ccatcaatag ccgacgcacg
    21181 agattgagct gtcgctgcgt gcgaaagcgg ctcgggctcg tgccgaacag ccgtcggaac
    21241 tggcgggcga tcgtccagcg gtcgagtccc gatgcgtgct cgagcgcgtc catcgagatc
    21301 ggctcgcgcg gacaggaggc gatgatatcg cggatacgtg tcaattcgac catcgcgagc
    21361 gggccggctt tcggcgcgct gcccttcgcg gcggcggccg tcagcaggtt cgcgacggcg
    21421 acggcgatgt cgatgcgcga tacgttgtcg atttcctcgt ccaggttcca gatgccggcc
    21481 gcgagcgcct cggaaacggc gggtgcctgg aagatcggtg agcgaacgaa cggcagcatg
    21541 cggccgccga gcgcttcctg gacgagcgcg ggatcgacgt agatgattcg gtaaccgaag
    21601 ccttcgtcgg ttcccgcgcg gccgtcgtgc aactcgtcgg ggtgcaggat atggcactgt
    21661 cccggcaggc agtggtggat ttcgccgaga tagccgaagg tttgcaagcc cgagagcgtg
    21721 atgccgatcg cgtacgtgtc gtgacgatgc ggcgtgaacg catgatcgag gaagtgcgcc
    21781 tccacgcgtt cgatgcctgg ggcgccggat ccgatccgaa tttgatctcg gtcgggcgcg
    21841 atgtcgcgtg cacaatcgtt caagacagcc tccctgacgc ttccataagc tacccattca
    21901 aaaaagatgg cgcgctggag cttcgatggt aaaccaagtc gacctcgttt cggagacatt
    21961 gcgctctctg gtggccctgc ttttcgctgc ggctgtggtg atgggcagcc ccgggccctc
    22021 caccgtcagt gcgaccgcga tgggcgcgtc ctacggagtg cgccggtcgc tcaagtatgc
    22081 gtggggcctc atcgcgggca cggtggcggt attgctgctc gtgtcgacgg gcgtgacggc
    22141 attcgtgatg tcgatgccga gcgcagcgag gattctcaat attgtttcgg ccctctacat
    22201 cctctatctc gcgtacagga tcgccaccgc gccgccactc gacaagcggg cggaaaacct
    22261 ctcgtctccc gctttcaagg ggggattcct gctggccgtc gccaatccga aggcgtatat
    22321 cgcgatcggc gcggtatttg cgggaacgac gctcgtcgcg actgattacg gtctcgatgc
    22381 cgcggccaag atcgttctgc tcagcgtaat gatcgtcatc atccatctcg gctggctatt
    22441 ggcgggcgta tcgctgtccc ggtttttgca cgaccccgtt gcgtctcgca tcatcaatgt
    22501 ttcgttggcg gcgatattag ccattgtttc gctgattgcg ctattcgaat gaaatactcg
    22561 acgtgccggc ctcatcgaag gcggcacgtt attttcagcg tggtgcaggg gggcggagtg
    22621 accgaaacgg cgcggaaacg gaaccctggt ttgccgtcgt caaaacgcgt tcgggacgat
    22681 cggcgtgtgc atgcgtgcgg cagccgatca taggcgcgtg acgcaggcat gtacttgcgg
    22741 cgcgatcgcg ccgcgaacgg gtcaccaagt cgacacgaat ctccggatac cggtcagcgc
    22801 gcgatgtgcg gatgcctttc cgttcgttgc agcgagacgc cgagcgtgcg cagcaattcc
    22861 catccgcccg tcttgctgta tgcgacgccg aattcgcgtt cgatcagctt gcgtactcgc
    22921 gcgagcgtcc actgcgggct tgcgaagccc gccgcgagcg cgccgtcgtc gagcatcgcg
    22981 cgaagcgtcg cgcattgcgc ggaattcagc cgccgtggcc gtcccggcgc cttcgcgatg
    23041 cgcccgtcgc gttccgcgag ccgtttcgcc catctgcaga ccgattgccg cgatacgacg
    23101 agccttcgcg caacgtcggc ctgcggcatg cccgattcga gcaagcgaaa gccttcggtg
    23161 cgccgttcgg cgatcggcga gccgccatcg tgcttcgtat ccatctgcgt tctcccggtt
    23221 gaaaaactca tggacgtgac ggattgctaa atgattgaaa agagcgacgc aaggccgatg
    23281 aagatcacat tagaatgtcc atgacgcagt cgaggtggaa atcctgctgg atcggaatga
    23341 ttgcgacgaa gacctgatcg cggtgcgccg gtgtgagcgc aatgagcgtg cgcatccggc
    23401 gcacgcccga agacgaacgc ccgcggtgcg ccggcggaga acggagaaga attcagatgg
    23461 ccaatgtcgg caaggcttgg aacatcgatg atttgagaaa aatggcgcga aagcgcgtgc
    23521 ccaaatattt cttcgattat ctggacggcg gcgcgaacag cgaaaccacg atgcgcgcga
    23581 acgaaaacga tttcgcgcgc tggcggctgc gtcagaaagt attgaccggc gcgcagagcc
    23641 gggttgcggg tttgggggcg acatacctcg gcgccgagca tcggcttccg attctgctcg
    23701 ggccggtggg atttgccggc atgtattggt cgcgcggcga gatcgcggcg ggacgcgcgg
    23761 ccgacgacgc gggcatcggt cagtgtttgt cgacgttctc gatctgttcg ctcgaggatg
    23821 tcgccgcggc gcgctccggt ccgctgtatt ttcagctcta catgttccgc gatcgcgatc
    23881 tgaccgagga cattctcgcg cgctgccggc tggcgaacgt cgacgccgtc tttctgacgg
    23941 tggacacctg ctatatcccg attcgcgaac gcgatgcgcg caacgggttt cgcgccgata
    24001 cgcgcttgtc ggcgcgcggg gtatggtcga tgctcaagcg cccgggctgg tgcgccggtg
    24061 cgttgtccca tggcgtgccg aggatcggca acgtgctgcg ctatccggag cttggcgcat
    24121 cgttgctcga gcaatccgcg gcggtcggcc ggatgatcga gacgcgcttg tcctgggccg
    24181 acgtcaagtg gctgcgcgcg cgctggcccg gcaggatcgt catcaagggg attctcgatc
    24241 ccgacgacgc gcggcgcgcg gtcgacgagg gcgtcgacgg catcctgatc tcgaatcatg
    24301 gcggccggca actcgatccg gcgccgtcgg tgatggacgt gttgccggag atcgccgagg
    24361 cggtcggcaa gcgcaccgag atcctgatgg acggcggtgt gcggcgcggt gcggacgtga
    24421 tcaaggcgct ggcgctcggg gccagcgcgg tctcgatcgg gcgcgcctac gtctatgggc
    24481 tcggtgcggc gggtgagaag ggcgtctcgc gatgtctcga attgctgaag ggcgagatgc
    24541 tgccggcgct caacatgatg ggctttgaat cggtcgcgga actcagggcc gcaggcaagt
    24601 ccgcgttgcg aatggcggtg ccggttcatg gcgcgacggc ggttgtcgaa ggggcggagg
    24661 gcggggcgcg tagactgacg gagagcgtgc tgtagcgtca acgtgccgat ggcgtgccgt
    24721 ggcgccgcaa ccggcggcgc acggcgctca tcacgcaggc tacttgcaga cgtcgaccca
    24781 ttcggcttcg accagctcgg ccaggcggac cggatcgatg cgcaacgcgg catgcgtcga
    24841 gcccgcggcc ggcacgacga actcgtacga cttcagcatc acgtcgcaat aaacgggcaa
    24901 cggagccgga aggccgaacg ggcaaacgcc gcccaccgga tggccggtga cggcgaccgt
    24961 ttcctccgcg gagagcattt tcgccttgcc gcccagcgcg gccttgattt tctggttgtc
    25021 gaggcgggaa tcgccgcagg atacgagcaa tacgtgtgcg tcgccgactt tcatcgcgag
    25081 cgtcttggcg atttgcgccg gcttgatgtc ccaggccgcc gacagcgtca tcgtggaact
    25141 gctttcgctc agcgcgatga catcgatatc cggcgccttt tccgccagga actggcgaac
    25201 cgattcaaca ctcacgttcg tggccctccg tgcagcctgc atgcccgctt ttgtattatc
    25261 ggcgggagca agggcaggct cgacgatcct tgctcccgca tctttggtga accctcggaa
    25321 cggataagct aacgcactcg gcgcaagttg tattgaacga ttgtgcaagc tcgcccgggg
    25381 cagtcatcga tgcatgacgt tcgaggtgag cgcggcccga tcgcggttcg gcgcgccgcg
    25441 catggtttgc gccgcgcggg gcgcgcgtac gcgcggcgct cgcgccgcgc gcgatgtcgc
    25501 ggccgccgtt gcgggggggc gcgggtcccg ggcgccgcgg gccgggttgc cggcaggccc
    25561 gttcatgcgc cgcgcatcgc gatccatgcc ccccagaaca gactcgcgaa aaatcgcacc
    25621 ggctcgcgga acccggcggc gtcgagcagc gcatgcaccg catcctcgga tgcgggaggg
    25681 tccgcgccgc gcaggatcgt cgcgagcttg cgcgcgactt cttccggcgt cgcgccgtgc
    25741 atccgccagc gctgcgccca cgcgctcagg agccgcggat gctcggcgta gcggcgatag
    25801 ttgcccgcga cgacgagcgg cgcgcccggc ttcaaccggc gtgcgatcga gcgcagcagc
    25861 gcggccttcg cgccgtcgcc ggccacgtgg tgcagcacgc cgatcagcgt cgcgccgtcg
    25921 aagcgggcgt cggcgggcaa atcgtcgaca tagccgaggt gcgtcgtcac gcgcgcatcg
    25981 agaccggccg cggcgatgtt cgcgttcgcg agatcgagca tcggccgcga cgggtcgacc
    26041 gccgtgaagc gccagccggg cgcgaggccg gcgagcgcgg cgatttcgcg cgcggtgccg
    26101 cccgcgcccg caacaaggac ctgcgcggca tgcgcttcgg cggggatcgc cgaagcgagc
    26161 atgcaagcgg cgaggtcgtg gcatgcgtcg tagcccgcga gcgcgatgcg gctttgctcg
    26221 gcgtattgag ctgcgcgcgc cggatcgaat ttggctgcgg cggacggcgt ggacatggcg
    26281 atcggactcc tgacgaatcg cgccgccgac aatggcgcgc gaaaccgcag cctaagcgcc
    26341 gacgcggcgc gcaacaaggc gagcggccat catggtatgg cggctaccgg ccatttcggg
    26401 gtcgcttcac gtttaaaacc tcccgccgaa tctcgcatcg taatgcgaat cggcgcatac
    26461 tgggtgcccc ttcttcgtcg ggccacgcgc gtcacgcatg cgcgccgcac acggcgcttc
    26521 gccatgcctc tgagcgcagg aggagcgcat catgtccgaa tgtcctcatg atccgtatgc
    26581 gcagcatcac tcgcattgcc tgccgttcgg cgcccagccc tgcggcgccg cgggcgcgac
    26641 gacacgcact cactttcgcg tctgggcgcc cgcgcatgcg gccgtgacgc tcgcgctcga
    26701 caccgcgggc ggcctgcatg aattgccgat ggcgcccgcg ggcgacggct ggttcgagac
    26761 gttcgccgat tgcggcgcgc atacgcgcta ccggtatcgg ctcgacgagg cgctgacgat
    26821 tcccgatccg gcgtcgcgct cgcagccgga aggcgccgac gggccgagcg aggtgatcga
    26881 tccgcgcgcg ttcacgtggc gccacacgtt ctggcgtggc aggccgtggg aggagatcgc
    26941 gctctacgcg atccagcccg gcgcggcggg cggttacgac ggtgtccgtg agcgcttgcc
    27001 gcagctcgcg cagttgggcg tcaccgcgct cgagttgctc gcggcgccgc aggcgcgcga
    27061 cgacagcctg ccgttcgcgc cgatcgccgc atacggcggc gtcgacgcgc tcaagcgcct
    27121 gatcgacgag gcgcacggtt tcggcctcgc ggtgctgctc gatctcgact atgcgcgctt
    27181 cggctgcggc tccgatgaaa tgcggcgcta cgcgcagccg ttcttccaca cccgcgacga
    27241 tccgctgcag gcgccgccgc tcgcgctcga ccacccgcag gtgtgcgact tcttctgcga
    27301 caacgcgctg tactggctcg aagaatatcg atgcgacggc ttgcggatcc gcgaggcgga
    27361 ccgcatcgac agcgcgtggc tgcgcgagat cgccgatcgc gtgcacgcgg cgatgccgac
    27421 cgaccggatc gtgcacctcg tgctcggcag cgagcggcat ccgtcgcacc tcgccgacac
    27481 gcatttcgac gcgcaatgga acggttgcgg cgagcgcgcg ctgtaccggc tgacggggcg
    27541 ccgcgatcgc gcgcacgacg acggcgtgtc gacgcatcag tcgatccatg cgcttgcgcg
    27601 cgcgttgacc gcgaacggcg cggtgttcca gcgcgcgcat ccggccggcg aaggcgggat
    27661 ggccgacgtc ggcctgccgc tgacctcgct cgtgctgtcc gacggcgtcg tgcgcgacgc
    27721 gcgcgaggcg gatctcgcgg cgctcgcgct gtcgctgctg acgccgcaga ttccgctgat
    27781 cttcgatgaa gccgcgggcg acgcgtcgcg gcgccatttc gtgcaatcgg cgctcgcggt
    27841 gcgcgcgaag ctgatcgcgc cgcgcctgat cgacgtgcgg ccgcgccgcg ccgacatgct
    27901 gcgcgcggcc gacggcgtcg aggccgatgc gcttgtcgcc gcatggcggc tcggcgacgg
    27961 cgagacgctc agcatcgcgc tgaacctgtc gccgcaggcg ttgccgtttc atggcgcgcc
    28021 ggacggaacg atcgtgttcg aaacgccggc gcgcgcgcgg gatcgcgtc
//
