LOCUS       NZ_KN150941            21123 bp    DNA     linear   CON 15-JAN-2024
DEFINITION  Burkholderia pseudomallei strain BFD scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KN150941
VERSION     NZ_KN150941.1
KEYWORDS    WGS; RefSeq.
SOURCE      Burkholderia pseudomallei
  ORGANISM  Burkholderia pseudomallei
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3267697)
  AUTHORS   Daligault,H.E., Davenport,K.W., Minogue,T.D., Bishop-Lilly,K.A.,
            Broomall,S.M., Bruce,D.C., Chain,P.S., Coyne,S.R., Frey,K.G.,
            Gibbons,H.S., Jaissle,J., Koroleva,G.I., Ladner,J.T., Lo,C.C.,
            Munk,C., Palacios,G.F., Redden,C.L., Rosenzweig,C.N., Scholz,M.B.
            and Johnson,S.L.
  TITLE     Whole-genome assemblies of 56 burkholderia species
  JOURNAL   Genome Announc 2 (6), e01106-14 (2014)
   PUBMED   25414490
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3267697)
  AUTHORS   Bishop-Lilly,K.A., Broomall,S.M., Chain,P.S., Chertkov,O.,
            Coyne,S.R., Daligault,H.E., Davenport,K.W., Erkkila,T., Frey,K.G.,
            Gibbons,H.S., Gu,W., Jaissle,J., Johnson,S.L., Koroleva,G.I.,
            Ladner,J.T., Lo,C.-C., Minogue,T.D., Munk,C., Palacios,G.F.,
            Redden,C.L., Rosenzweig,C.N., Scholz,M.B., Teshima,H. and Xu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-2014) Bioscience, Los Alamos National Laboratory,
            P.O. Box 1663, MS M888, Los Alamos, NM 87545, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2013
            Assembly Method :: Newbler v. 2.6; Velvet v. 1.2.08; AllPaths v.
            44837; phredPhrap v. SPS - 4.24
            Assembly Name                     :: BFD
            Genome Coverage                   :: 304.0x
            Sequencing Technology             :: 454; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/15/2024 02:34:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,650
            CDSs (total)                      :: 6,571
            Genes (coding)                    :: 6,399
            CDSs (with protein)               :: 6,399
            Genes (RNA)                       :: 79
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 172
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 172
            Pseudo Genes (frameshifted)       :: 87 of 172
            Pseudo Genes (incomplete)         :: 122 of 172
            Pseudo Genes (internal stop)      :: 22 of 172
            Pseudo Genes (multiple problems)  :: 48 of 172
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:41:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1541069
            Orig. end                         :: 1562192
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KN150941.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21123
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="9"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..21123
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21123
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:16123](+)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..16123
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     gene            complement(626..2140)
                     /locus_tag="DP56_RS06175"
                     /old_locus_tag="DP56_886"
     CDS             complement(626..2140)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011852789.1"
                     /locus_tag="DP56_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_886"
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="WP_038756130.1"
                     /transl_table=11
                     /translation="MPTSRILAPSLRSLVRTADEAAALIGPNMTVAMSGFTGSGYPKAV
                     PAALAARIAASHARGEDFRINVLTGASTAPELDGALAKADGISMRLPYQSDPTLREKIN
                     AGELDYQDIHLSHVAQYAWFGLFGELDVAIVEVAGIREDGRLIPSASVGNNKTWLDQAK
                     RVILEVNARQPLGLDGMHDIYYGTALPPNRKPIPLVKSDDRIGEPYLRCPAEKIVAIVE
                     TDVPDRSNAFAAPDETSKQIAGLLIDFLRHEIKRGRLPEHLLPLQSGVGNITNAVLAGL
                     GEGGFSNLSAYTEVIQDGMLDLLANGTLSFASATALSLSPDAVKRFADEIDTFRSKIVL
                     RPQEISNHPELVRRLGIIAMNGMIEADIYGNVNSTHVMGTRIQNGIGGSGDFARNGYLS
                     CFMSASTAKGGAISRIVPMASHVDHTEHDVAVVVTEQGLADLRGLSPKQRARKVIANCA
                     HPDYRPMLEDYFERASRESFGKQTPHLLGEALSWHERYVRTGSMKA"
     misc_feature    complement(2317..2331)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.89"
                     /tool="antismash"
     misc_feature    2331..2344
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            2505..3194
                     /locus_tag="DP56_RS06180"
                     /old_locus_tag="DP56_887"
     CDS             2505..3194
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603979.1"
                     /locus_tag="DP56_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_887"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_038756133.1"
                     /transl_table=11
                     /translation="MDPRKSATHRIPSPPPRTWDARLARRLVTPLVGTPVTPNHLTTLR
                     LLIGLAGAWCLTQPGFGWSNAGALLIVLSNFVDHTDGELARISGQSSKLGHFYDLASDA
                     FVTVALFVSMGAGVVAAGGQMAASPVLLGAVAGAAVALIFFLRMRIESFAGKAGTKQAF
                     VGGFETEDVLYLLPVVTLLDGVEPFLLAASIGAPLFAAWVVLDYWRIVRRGAGAGAPNS
                     TEIQPSK"
     gene            3191..3964
                     /locus_tag="DP56_RS06185"
                     /old_locus_tag="DP56_888"
     CDS             3191..3964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009969809.1"
                     /locus_tag="DP56_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_888"
                     /product="hypothetical protein"
                     /protein_id="WP_004542606.1"
                     /transl_table=11
                     /translation="MMMDLEAPAAHGSADAAVAARVAVLDRARLRGEFARQDAFLYLDE
                     FLPKDLAGRVADCARALVPEINRNYLPGHKQGGSVSRHTIDEKAPLIAELYRSKALVGF
                     LETLTGDKLLPSPDDDPHAYALYYYTKPGDHIGWHYDTSYYDGRRYTLLFGVIDDSTSR
                     LDYTLHTRNPAVPDEPGSVQIAHGGIVFFDGDKLRHRVTPLGENEIRVSLTFEYVTDPG
                     MRPWKRFVSNMKDAIAYFGFRQVFKQTAARRSPRS"
     gene            3961..4962
                     /locus_tag="DP56_RS06190"
                     /old_locus_tag="DP56_889"
     CDS             3961..4962
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006029770.1"
                     /locus_tag="DP56_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_889"
                     /product="HpnL family protein"
                     /protein_id="WP_004542630.1"
                     /transl_table=11
                     /translation="MTRTGMILLSLGTAAFVALLAWQGLGAVAATLASAGWGLALVAAF
                     HLVPLVIDATAIAVMFRPGEPGSRLGEALRARWVGEAVNSLLPAGQIGGPVLMVRYLAQ
                     RGARLADAAAAITVSTTMQALAQMVFALVGIATFSAYATHDAAAHLRTPALIATAVLGG
                     CAALFYCAQRRGLFGRGLRAASTLLGPRDWSSLATRADAIDHALDRLYRERAKVRATFV
                     LSFVGWIVGTAEVWLALRFLGHPVSWLDALLLESVGQAIRGAAFAIPGSLGAQEGGYLL
                     LAPLVGLPPDAALALSLAKRARELALGLPGLLYLHFSERNWQRRRAPQPIAD"
     gene            5001..5768
                     /locus_tag="DP56_RS06195"
                     /old_locus_tag="DP56_890"
     CDS             5001..5768
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603691.1"
                     /locus_tag="DP56_RS06195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_890"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_004525541.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 4.1e-18, bitscore:
                     63.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAIILAAGLGLRLQLPPEAQFPKCLLRFDDTSLLERHLRVLDAA
                     GVDEIVLALGFQSEKVEAELARLNRRAEIVLNPRYDLGSVLTVHTAADALTRGGDVLLM
                     DADVLYDEAILHALVADPSRAIDRLLIDRDFEAGDEPVKLCVKDGVPVELRKQLAAGLE
                     YDTIGESVGFFRFSEGTARRLAEIVAGYVDGGRANMPHEEAVRDLLLEGGRTFDIADVT
                     GSPWIEIDFPGDVARARDEVLPHIQQRTIGAIR"
     misc_feature    5028..5030
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5765..7453
                     /gene="aepX"
                     /locus_tag="DP56_RS06200"
                     /old_locus_tag="DP56_891"
     CDS             5765..7453
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="aepX"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004542643.1"
                     /locus_tag="DP56_RS06200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_891"
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="WP_004525540.1"
                     /sec_met_domain="phosphonates (E-value: 1.7e-130, bitscore:
                     431.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates-like (E-value: 3.5e-142,
                     bitscore: 469.7, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-67, bitscore:
                     225.5, seeds: 69, tool: rule-based-clusters)"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.7e-15, bitscore:
                     54.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAREPNFTESRSARLRRMLTSPSLEFLMEAHNGLSARIVREAGF
                     KGIWASGLAISAQFGVRDNNEASWTQVVDVLEFMADASDLPILLDGDTGYGNFNNVRRL
                     VRKLEQRGIAGVCIEDKQFPKTNSFIDGERQPLAEIDEFCGKIKAGKDSQSDPDFSIVA
                     RVEALIAGWGMDEALRRANAYAQAGADAILIHSKLSRPDEILQFAREWSGRAPLVIVPT
                     KYYSTPTDVFRQAGISTVIWANHLIRASASAMQAVAREIQDSETLVNVEERVASVNEIF
                     RLQDADEYSAAERIYLSSSARASSAALVLAASRGNGLEAVTEDKPKVMLPVAGKPLLRW
                     LVDGFKKQGVNDITVVGGYRADAIDTSGVKLVVNERHAQTGELASLACAAERLTGDTII
                     SYGDLLFRSYILRDLAESEAQFSVVVDSSQTQPSNQSVRDFAFCSAADDRGLFGQKAYL
                     RRVSSDASEAAPHGRWIGLLNVRGAGVARLKAMLGTLQARDDFDALDLPALLNALVDAG
                     EQIEVQYVHGHWRGVNDLDDFRRAGDFAHGQTPYAEQNAGSGSAR"
     gene            7450..8631
                     /gene="aepY"
                     /locus_tag="DP56_RS06205"
                     /old_locus_tag="DP56_892"
     CDS             7450..8631
                     /EC_number="4.1.1.82"
                     /GO_function="GO:0033980 - phosphonopyruvate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aepY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525539.1"
                     /locus_tag="DP56_RS06205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_892"
                     /product="phosphonopyruvate decarboxylase"
                     /protein_id="WP_004530031.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1e-11, bitscore:
                     42.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.3e-16, bitscore:
                     55.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAAQFVEAARARGFDWYAGVPCSYLTPFINYVLQDPALHYVSA
                     ANEGDAVALVAGATLGGRRGIAMMQNSGLGNAVSPLTSLTWTFRLPQLLIVTWRGQPGV
                     PDEPQHALMGPITPAMLDTMEIPWETFPTQADAIGPALDRAIAHMDATGRPYALVMQKG
                     SVAPHALEHASMPERRAHAAARATPGAAAPSAWPTRHDALARIVARTPADSTVVLASTG
                     FCGRELYALDDRPNQLYMVGSMGCVTPLALGLALARPDLTVVALDGDGAALMRMGAFAT
                     LGAYGPPNLVHLLLDNGAHESTGGQATVSQYVSFAGIAAACGYATAIEGDDLGVLDAAL
                     DAARAGEQAVEHGGAHFARLSIRTGVPDGLPRPTVTPVDVKTRLMRHIGAMPA"
     gene            8646..9713
                     /locus_tag="DP56_RS06210"
                     /old_locus_tag="DP56_893"
     CDS             8646..9713
                     /NRPS_PKS="Domain: Aminotran_5 (25-346). E-value: 7.4e-28.
                     Score: 89.4. Matches aSDomain:
                     nrpspksdomains_DP56_RS06210_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187270.1"
                     /locus_tag="DP56_RS06210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_893"
                     /product="2-aminoethylphosphonate aminotransferase"
                     /protein_id="WP_004525538.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2.7e-20, bitscore:
                     70.0, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8e-05, bitscore:
                     19.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLLNPGPVTLTERVRQSLLQPDLCHRESEFFDLQDEARARLVAA
                     YALDPAEWSAVLMTGSGTAAVESMIAALVPENGKLLVIENGVYGERITQIATQYRIAHD
                     VLKHDWMQAPDLARVAEKLDADRAITHVAVIHHETTTGRLNDLDALAAVCRARGVRMLV
                     DGVSSFGAEAIDFAGGDIDALAATANKCLHGVPGAAFVIVRRRALASAASRTYYLDLGR
                     LAKLQDARNTPFTPSVHAYYALVEALREFDEAGGWRARHARYAALAEQVRAGLAARGMP
                     LVLPDGESSVVLRAYRLPAGVAYEQLHDGLKARGFVIYAGQGGLSSALFRVSTMGAIEP
                     ADVERLLDGFTALAR"
     aSDomain        8721..9683
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DP56_RS06210_Aminotran_5.1"
                     /evalue="7.40E-28"
                     /label="DP56_RS06210_Aminotran_5.1"
                     /locus_tag="DP56_RS06210"
                     /protein_end="346"
                     /protein_start="25"
                     /score="89.4"
                     /tool="antismash"
                     /translation="HRESEFFDLQDEARARLVAAYALDPAEWSAVLMTGSGTAAVESMI
                     AALVPENGKLLVIENGVYGERITQIATQYRIAHDVLKHDWMQAPDLARVAEKLDADRAI
                     THVAVIHHETTTGRLNDLDALAAVCRARGVRMLVDGVSSFGAEAIDFAGGDIDALAATA
                     NKCLHGVPGAAFVIVRRRALASAASRTYYLDLGRLAKLQDARNTPFTPSVHAYYALVEA
                     LREFDEAGGWRARHARYAALAEQVRAGLAARGMPLVLPDGESSVVLRAYRLPAGVAYEQ
                     LHDGLKARGFVIYAGQGGLSSALFRVSTMGAIEPADVERL"
     gene            complement(9859..10626)
                     /locus_tag="DP56_RS06215"
                     /old_locus_tag="DP56_894"
     CDS             complement(9859..10626)
                     /EC_number="4.2.1.-"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004530029.1"
                     /locus_tag="DP56_RS06215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_894"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_038756136.1"
                     /transl_table=11
                     /translation="MRGDAHRRLAHFVFHHHFRKGRPMSATARRPLKTGFLLAPGVAVM
                     DLFGAHAVFGFAPRSELHLLWKTREPISALPPFPIAATTTFADCPDELDAFVVGAVPAD
                     VIADDEVIAFVRRQASRARYVIGICGGVLLLGAAGLLNGRRATTNFHVLDALAELGARP
                     VGGGEVVIDGNLYTAGPATGGFEAALLVLAELRGAEAAKHVELTIEYHPRAPFGVGTPA
                     LAGPALTNEVLAAHAWFFDPCKDAARAAYERGR"
     misc_feature    10666..10684
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.63"
                     /tool="antismash"
     gene            10699..11664
                     /locus_tag="DP56_RS06220"
                     /old_locus_tag="DP56_895"
     CDS             10699..11664
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011852785.1"
                     /locus_tag="DP56_RS06220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_895"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_004196021.1"
                     /transl_table=11
                     /translation="MRLIVYILVFPDLNLLDLSGPLQVLSSANELSREAGADAPYDIRV
                     VARGGRSVRTSTGISLSTQPLAPIDAPADTVIVAGGAGVDAAARCADTLAWLRAHARQA
                     RRVVSICNGAFLLAACGLLDGRRAVTHWQCCDALARRHPRVRVEHAPIFVQDGPIWTSA
                     GVTAGIDLCLRLVSNDCGHTLALALARYLVVFLVRPGSQAQFSESIEMQSASGQFADLH
                     AWIRRHLRADLSVPTLAARVNMSERSFVRHYRNAFGTTPAKAVERIRVETARNLLGETA
                     LPVKQIAQRCGFGSVATLRRSFARAFDTSLHEYRERFRQA"
     gene            11903..12976
                     /locus_tag="DP56_RS06225"
                     /old_locus_tag="DP56_896"
     CDS             11903..12976
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004202241.1"
                     /locus_tag="DP56_RS06225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_896"
                     /product="FUSC family protein"
                     /protein_id="WP_004187681.1"
                     /transl_table=11
                     /translation="MTSTLQSRLPGLVRNALRPVLDPYRRYRHAKLIHAARVALSVLAS
                     IALTTGLHVPHGEWATITVLIVIGGLQHHGNIRKKAAERALGTLIGAIAGLSLILLQTT
                     VHLSPLTFLVMSVACGLCAYHAIGKAGYIALLSAITMVIVAGHGDNEIADGLWRAVNVL
                     VGIVIALAFSFALPLYATYSWRYKLADALRGCAAVHARIAGERYVSDNERLKDMAALNA
                     LLVQLRSLMPSVSKEISVSMPQLEAIQRSLRLCMSALEILSSRQPGEDDAAGRRFVQIQ
                     MKADNRRIQEMLVGAARALKFGTPGRLGPLHGPAAAVGENVPPADLSGYVSLTAKLSHE
                     IEQLRQRLRDTAPQWNI"
     misc_feature    11915..11917
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13306..14517)
                     /locus_tag="DP56_RS06230"
                     /old_locus_tag="DP56_897"
     CDS             complement(13306..14517)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004535247.1"
                     /locus_tag="DP56_RS06230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_897"
                     /product="multidrug effflux MFS transporter"
                     /protein_id="WP_038756139.1"
                     /transl_table=11
                     /translation="MNTTETNTLSDRGWLSLLMLVVCLPRMTIDAYLPSLPAMADALHG
                     TDAQMQLTLTMYMAGYALSMLLSGPLSDRYGRRPVLLAGMLVYLGASVACATATSVQGI
                     VVARIGQALGGCCGTVIGRVIVRERFGTAMQAAMLSRISAGMALSPVVAPLAGHVVAQW
                     LGWRGVFASLAFGGGAAALMVHRFLPETRVRAAASERGAGLAKTYLSLLRDRRFVRYSL
                     AIGFVYCTYFPFIAESSALFQRTLRASGAVYAAIFGITVLGYLIGSSVFRRASGRFGID
                     AIIASAAFVNLVGAAALWIGTSVAPPSVWSIALPMFVVMVSVGVSIPACQFAVLQPFAK
                     LAGTASGLFFFIQMAMTAGCGGMLSRLSDGSARPMAVVTAASSAAFMAVVMLVRTRGAN
                     GRHG"
     misc_feature    14499..14516
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.01"
                     /tool="antismash"
     misc_feature    complement(14594..14608)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.13"
                     /tool="antismash"
     misc_feature    14596..14612
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.57"
                     /tool="antismash"
     misc_feature    complement(14599..14613)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            14621..16123
                     /locus_tag="DP56_RS06235"
                     /old_locus_tag="DP56_898"
     CDS             14621..16123
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (166-430). E-value:
                     1.5e-18. Score: 59.0. Matches aSDomain:
                     nrpspksdomains_DP56_RS06235_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004196023.1"
                     /locus_tag="DP56_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_898"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_038756142.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.1e-17, bitscore:
                     59.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARGKTAIPLDLPRPPGLSVRRAQSKQDCIGDALRDAILRKLLPG
                     GSPLPSTRTLAARWGVARGTVEAAFDRLCAEGYIARAHGSGTRVSAVVPDAYLSPARHP
                     AKPAPHARGKPADALARERAAEADGSVRAGVPFVARLADPGLLPMRTWKRHIGIGLSEA
                     THAALCALPPQGAEPLRARIADYLGQYRGIACDAADIFITTGIRHSLDLIARTIAGSGS
                     RIAIEDPGYRTARRIFELAGAESICVAVGPEGIDTHALSAHRRVAAAYVTPAHQSPLGV
                     TMSISRRLDLLDWAHARRTWVIEDDYDGEFGYQSAPLPALKSLDVRNRVIYCGSFNKTL
                     FSGLRVGFMVVPAALRAPISALVQAVGRPVGTTEQLALASFIGSGDFAKHLRTSRHAYL
                     QRRDAVLEQLRRYADGQYAISGEHTGFHFVLWLGRGIDERTFAEEAANIGLALEPLRAF
                     CTQAALPAGVVVGYSALSVAQARYAGKELGQLLAGVRRDAAA"
     aSDomain        15119..15910
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DP56_RS06235_Aminotran_1_2.1"
                     /evalue="1.50E-18"
                     /label="DP56_RS06235_Aminotran_1_2.1"
                     /locus_tag="DP56_RS06235"
                     /protein_end="430"
                     /protein_start="166"
                     /score="59.0"
                     /tool="antismash"
                     /translation="ALCALPPQGAEPLRARIADYLGQYRGIACDAADIFITTGIRHSLD
                     LIARTIAGSGSRIAIEDPGYRTARRIFELAGAESICVAVGPEGIDTHALSAHRRVAAAY
                     VTPAHQSPLGVTMSISRRLDLLDWAHARRTWVIEDDYDGEFGYQSAPLPALKSLDVRNR
                     VIYCGSFNKTLFSGLRVGFMVVPAALRAPISALVQAVGRPVGTTEQLALASFIGSGDFA
                     KHLRTSRHAYLQRRDAVLEQLRRYADGQYAISGEHTGFHFVL"
     gene            complement(16381..17403)
                     /locus_tag="DP56_RS06240"
                     /old_locus_tag="DP56_899"
     CDS             complement(16381..17403)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004542546.1"
                     /locus_tag="DP56_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_899"
                     /product="transglutaminase family protein"
                     /protein_id="WP_038729837.1"
                     /transl_table=11
                     /translation="MGMTTRPQANAKARARKAAARGEPARGALLRVTHDTRYRYAARVE
                     SAQHQARLRPLETPRQRVIEFSLEIEPRAEGLVVDIDSFGNERASFALNQPHEELFVRS
                     RSVVRVTPPALAAGKRGEPPPAVAAPRDGCASAWEAVRERLTFRAGRPFDPASEFVFAS
                     PHVACHSDLAAYAAASFTPGRPLVQAAWELMRRIHADFAYAPNSTDVGTTALDALALRQ
                     GVCQDFAHVMIGALRSLGLAARYVSGYLLTQPPPGQPRLIGADASHAWVEVYDPAWPED
                     GGWLPLDPTNDRAPGDDYVMLSIGRDYADVTPLRGVIRGGGADQVLAVGVTVEPLDSAS
                     "
     gene            complement(17394..20090)
                     /locus_tag="DP56_RS06245"
                     /old_locus_tag="DP56_900"
     CDS             complement(17394..20090)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004538027.1"
                     /locus_tag="DP56_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DP56_900"
                     /product="circularly permuted type 2 ATP-grasp protein"
                     /protein_id="WP_004187774.1"
                     /transl_table=11
                     /translation="MRRPGGSAPPSLKNRIVLSLSSDDDLTADAMQTLFDTGSQQDAAE
                     FGAALAAPAVTGRYDELRGGAAALSSASLAPAWRAFFTQLGSVGFADLDRRADALQRRM
                     RENGLAYHPHERAAGGGAVRPWSLDLLPLIIAPDDWAAIERGVLQRVRLSNAILADLYG
                     EQTILRRGLLPPALVTGHPGYLRPMCGAQAPGGTWLHVAAFDLARGPDGAWRLMAQHTQ
                     GPAGLGYLLENRLIVSRLFPRAFRGLHVQRLAASYRALLQSMQALSPARKNSRIVLLTP
                     GPHAATYFEHAYLARYLGLTLVEGGDLTARDQRVYLKTLRGLEPVHGILRRVDDEWLDP
                     LELRPDSLLGVPGLMQAVRAGNVLLANLPGSGFLESPGILGFLPRLAQALLDETLTLPA
                     VHSWWCGEQAACDEALPLLARGIVKPTFPASVQAGGAFEPVIGARLSPRQLADWRARIA
                     AQPAHYTIQADLPLSQAPTWAAGAGMGDGGARIVPRPLLLRVFALADGARSWRVLPGGL
                     ARVGTRDELFNAPMPHGGSSVDTWVMTEGAVDPTTLLQTHLGPDDLQERSRAIASRAAE
                     NLFWLGRYTERATNLTRLARAALERLRGEDDVETPVHLHVLDALCRDNGLLPADAPPAV
                     DAPRAFQQALTRSLTPRADRSTGIASCLFGMRGAAAAIRERLSREQWRLIDEATQLFDE
                     GGDDAEPEEQLGNDALQRLERLNLLLSAITGAQTDNMTRDDGWRLLSIGRQIDRLEFLC
                     GVLGHAFDGGAIHKQEGFELVLELFDSGITFRSRFQRCFDVAPLLSLVVLDTDNPRSLA
                     WVAQALRGRLSKVERSEGYALSELADGIPDIAGWPLHVLCETDGDGRHAALLARLQACG
                     KAAWDVSNRIGERYFSHVRDAGRSLWG"
     gene            complement(20054..20233)
                     /locus_tag="DP56_RS42760"
     CDS             complement(20054..20233)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004537245.1"
                     /locus_tag="DP56_RS42760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004525531.1"
                     /transl_table=11
                     /translation="MSGCGAAAVLVAQPRRPRRRRDRCVARRAGDVALAACGNVRIRHR
                     RAACAAPAARRRRP"
ORIGIN
        1 atgacgaact ttcttagaag aggttgtgtg ttggcggttt cccggcgcaa ccgagtacct
       61 cctcgagatt ctcgcactcg tcgacatgct cggcgtgtga cgaaggtctc tatatgtata
      121 tgcgtataca gatacgccgg cgttcggcga tacgcccacc tccgaacgaa catcgcccga
      181 tgatcgccac agtcgcttcg cccgcgtgcc cgccgtcggc tcgatcggct cgagcaatcc
      241 gaccatccgc gcgcgaatcc aacatgcctc gtgtcgtccg cctcgacgcg agcgacgaaa
      301 cgggcggctg cgcgtgttgc caccatgccg acactcgcga cattcgccga tgcgcgtcgc
      361 gcgcctcgag caagccacta gacaccaaag caccaagaca ttacatgccc gcgcctcttg
      421 cacgccgcag cacgccgcag cacgccgccg cgcgatgcgg cgcgttgccc gccgagcggc
      481 gcgcgccgcc tcgcaacgac agccgacgat caaccccggc accgcgcatt gacgaaacgg
      541 cgcggccacc ttgtggtgcc gcgccgtttc aatcgccggt ccgaacgggc gctgccgccc
      601 gcccggtgcg ttgccgcgcc gggcgtcagg ctttcatcga tccggtccgc acgtagcgct
      661 cgtgccacga cagcgcttcg ccgagcagat gcggcgtctg cttgccgaag ctctcgcggc
      721 tcgcgcgctc gaagtagtct tcgagcatcg gccggtaatc gggatgcgcg cagttcgcga
      781 tgaccttgcg cgcgcgctgc ttcggcgaca gtccacgcag atccgcgagc ccctgctcgg
      841 tcacgacgac cgcgacgtcg tgctcggtat ggtcaacgtg gcttgccatc ggcacgatcc
      901 gcgaaatcgc gccgcccttg gcggtgctcg ccgacatgaa gcacgacaga tagccgttgc
      961 gcgcgaaatc gccggagccg ccgatcccgt tctgaatcct cgtgcccatc acgtgcgtcg
     1021 agttcacgtt gccgtagata tcggcctcga tcatcccgtt catcgcgatg atgcccaggc
     1081 gccgcacgag ttccggatgg ttgctgattt cctgcggccg cagcacgatc ttcgagcgga
     1141 acgtatcgat ctcgtcggcg aagcgcttca ccgcatccgg gctgagcgac agcgcggtcg
     1201 ccgacgcgaa gctcagcgta ccgttcgcga gcagatcgag catgccgtcc tgaatcactt
     1261 ccgtatacgc gctcaggttc gagaaaccgc cttcgccgag gccggcgagc accgcgttcg
     1321 tgatgttgcc gacgccggac tgcagcggca gcaggtgttc gggcagacgg ccgcgcttga
     1381 tctcgtgacg caggaagtcg atcaggagtc cggcgatctg cttggaggtc tcgtccggcg
     1441 cggcgaacgc gttgctgcgg tccggcacgt cggtctcgac gatcgcgacg atcttctcgg
     1501 ccgggcaacg cagatacggc tcgccgatcc ggtcgtcgct cttcacgagc ggaatcggct
     1561 tgcggttcgg cggcagcgcg gtgccgtaat agatgtcgtg catcccgtcg agaccgagcg
     1621 gctggcgcgc gttcacctcg aggatcacgc gcttggcctg gtcgagccac gtcttgttgt
     1681 tgccgaccga cgccgacgga atcaggcgcc cgtcctcgcg aatgcccgcg acctcgacga
     1741 tcgcgacgtc cagctcgccg aacaggccga accacgcgta ctgcgcgacg tggctcaggt
     1801 ggatgtcctg atagtcgagc tcgcccgcgt tgatcttctc gcgcagcgtc ggatcggact
     1861 ggtacggcag ccgcatcgag ataccgtccg ccttcgcgag cgcgccgtcc agctcgggcg
     1921 cggtcgacgc gcccgtcagc acgttgatgc ggaaatcttc gccgcgcgcg tgggaagccg
     1981 cgatccgcgc ggcgagcgcg gccggcaccg ccttcggata gccggagccg gtgaagccgc
     2041 tcatcgcgac ggtcatgttc gggccgatca gcgcggcggc ctcgtcggcg gtgcgaacga
     2101 gggagcgcag gctgggggcg aggatacgag aggttggcat ggctgaatgt cgaacggttg
     2161 tagtagatct ggcgacgctg cgccgcaggg gtgtctccgg agtggcgcgc gctcccggcg
     2221 cctgcggcaa tcgcaagagg ggcggcggaa gcacggccgg agtatcgcag accgcaccgc
     2281 gccgtagtgt ccgccccgtg caaaagtaac ttgccggatt tgctggatat ttgcccgaaa
     2341 tcaaaccccg gcgcgacttg gcggcgcggc ccggtcgagg ttcgggggtt gcggcggccg
     2401 cggacagccg acgccaaacc ttacactttt ctttctgttg cgcgcaatca gcacgctcca
     2461 gtcatgaaaa agcaataaat tacgattccg tatatatttc gccgatggac ccgagaaaat
     2521 ccgccaccca ccgtattccg agcccgccgc cgcgcacctg ggacgcccgg ctcgcgcgcc
     2581 ggctcgtcac cccgctcgtc ggcacgccgg tcacgccgaa ccacctcacc acgctgcgcc
     2641 tgctgatcgg cctcgccggc gcatggtgcc tcacgcagcc gggcttcggc tggagcaacg
     2701 ccggcgcgtt gctgatcgtg ctgtccaatt tcgtcgacca caccgacggc gaactcgcgc
     2761 ggatcagcgg ccagtcgagc aagctcggcc acttctacga tctcgcgagc gacgcgttcg
     2821 tcacggtcgc gctgttcgtc agcatgggcg ccggcgtcgt cgccgcgggc ggccagatgg
     2881 ccgcatcgcc cgtgctgctc ggcgccgtcg cgggcgcggc cgtcgcgctc atcttcttcc
     2941 tgcgcatgcg catcgagtcg ttcgccggca aggcgggcac gaagcaggcg ttcgtcggcg
     3001 gcttcgagac cgaggacgtg ctgtatctgc tgcccgtcgt cacgctgctc gacggcgtcg
     3061 agccgttcct gctcgcggcg tcgatcggcg cgccgctgtt cgccgcatgg gtcgtgctcg
     3121 actactggcg catcgtgcgc cgcggcgccg gcgccggcgc gcccaattca accgaaatcc
     3181 agccctcgaa atgatgatgg acctcgaagc accggcggcg cacggttcgg ctgacgccgc
     3241 cgtcgccgcg cgcgtggccg tgctcgaccg cgcgcggctg cgcggcgagt tcgcgcgcca
     3301 ggacgcgttc ctctatctgg acgaattcct gccgaaggat ctcgccggcc gcgtcgcgga
     3361 ctgcgcgcgc gcgctcgtgc cggagatcaa ccgcaactat ctgccgggcc acaagcaagg
     3421 cggcagcgtg agccgccaca cgatcgacga gaaggcgccg ctcatcgccg agctttaccg
     3481 ctcgaaggcg ctcgtcggtt tcctcgagac gctgacgggc gacaagctgc tgccgtcgcc
     3541 ggacgacgat ccgcacgcgt acgcgctcta ttactacacg aagccgggcg atcacatcgg
     3601 ttggcactac gacacgtcgt actacgacgg ccgccgctac acgctgctct tcggcgtgat
     3661 cgacgattcg acgagccggc tcgactatac gctgcacacg cgcaatccgg ccgtgccgga
     3721 cgagccgggc tcggtgcaga tcgcgcacgg cggtatcgtg ttcttcgacg gcgacaagct
     3781 gcgccaccgc gtgacgccgc tcggcgagaa cgagatccgc gtgtcgctca cgttcgaata
     3841 cgtgaccgac ccgggcatgc gcccgtggaa acgcttcgtg tcgaacatga aggacgcgat
     3901 cgcgtacttc ggcttccgtc aggtattcaa gcaaacggcc gctcgccgct cgccgcgctc
     3961 atgacgcgca ccggcatgat cctgctgtcg ctcggcacgg cggcgttcgt cgctctcctc
     4021 gcgtggcagg gcctcggcgc ggtcgcggcg acgctcgcat cggccggctg gggcctcgcg
     4081 ctcgtcgcgg cgttccacct ggtgccgctc gtcatcgatg cgacggcgat cgcggtgatg
     4141 ttccgtccgg gcgagcccgg cagccggctc ggcgaagcgc tgcgcgcgcg ctgggtcggc
     4201 gaggcggtga acagcctgct gcccgccggg cagatcggcg ggccggtgct gatggtccgc
     4261 tatctcgcac agcgcggcgc gcgcctcgcc gacgcggcgg ccgcgatcac ggtcagcacg
     4321 acgatgcagg cgctcgcgca aatggtgttc gcgctcgtcg gcatcgcgac gttcagcgcg
     4381 tacgcgacgc atgacgccgc cgcgcatctg cgcacgccgg cgctgatcgc gaccgcggtg
     4441 ctgggcggct gcgccgcgct cttctactgc gcgcagcgcc ggggcctgtt cgggcgcggg
     4501 ctgcgcgcgg cgtcgacgct gctcggcccg cgcgactggt cgtcgctcgc cacgcgcgcg
     4561 gacgcgatcg accacgcgct cgaccggctg taccgcgagc gtgcgaaagt ccgcgcgaca
     4621 ttcgtgctga gcttcgtcgg ctggatcgtc ggcaccgcgg aagtgtggct cgcgctgcgc
     4681 ttcctcggcc acccggtgag ctggctcgac gcgctgctgc tcgagagcgt cgggcaggcg
     4741 atccgcggcg ccgcgttcgc gatccccggc tcgctcggcg cgcaggaagg cggctatctg
     4801 ctgctcgcgc cgctcgtcgg cctgccgccc gacgcggcgc tcgcgctgtc gctcgccaag
     4861 cgcgcgcgcg agctcgcgct cggcctgccc ggcctcctgt acctgcattt cagtgaaaga
     4921 aactggcagc ggcggcgcgc gccgcagccg atcgccgact gatccggcgt gatggtcggc
     4981 gccctttgcg tggagaactc atgcgagcca tcattcttgc ggcgggctta ggcctgcgcc
     5041 tgcaactgcc tcccgaggct caattcccga agtgcctgct gcgcttcgac gacacgtcgc
     5101 tcctcgagcg gcacctgcgc gtgctcgacg cggcgggcgt cgacgagatc gtgctcgcgc
     5161 tcggcttcca gtcggagaag gtcgaggccg agctcgcgcg gctgaaccgc cgggccgaga
     5221 tcgtgctcaa cccgcgctac gacctcggca gcgtgctgac cgtccacacg gcggccgacg
     5281 cgctcacgcg cggcggcgac gtgctgctga tggacgccga cgtgctctat gacgaggcca
     5341 tcctgcacgc gctcgtcgcc gatccgtcgc gcgcgatcga ccgcctgctg atcgaccgcg
     5401 atttcgaagc gggcgacgag cccgtcaagc tgtgcgtgaa ggacggcgtg ccggtcgagc
     5461 tgcgcaagca gctcgccgcg ggtctcgaat acgacacgat cggcgaatcg gtcggcttct
     5521 tccgcttcag cgaaggcacc gcgcggcggc tcgccgagat cgtcgcgggc tacgtcgacg
     5581 gcggccgcgc gaacatgccg cacgaagagg cggtgcgcga cctgctgctc gaaggcggcc
     5641 gcacgttcga catcgcggac gtgacgggct cgccgtggat cgaaatcgac tttccgggcg
     5701 atgtcgcgcg cgcgcgcgac gaagtcctgc cgcacatcca acaacgcacg ataggggcca
     5761 tccgatgaat gcacgcgaac cgaacttcac cgaatcgcgc agcgcgcggc tgcggcggat
     5821 gctgacgagc ccgtcgctcg aattcctgat ggaggcgcac aacggcctgt ccgcgcgcat
     5881 cgtccgcgag gcgggcttca agggcatctg ggcgtcgggg ctcgcgatct ccgcgcaatt
     5941 cggcgtgcgc gacaacaacg aggcgagctg gacacaggtg gtcgacgtgc tcgaattcat
     6001 ggccgacgcg agcgacctgc cgatcctgct cgacggcgac accggctacg gcaacttcaa
     6061 caacgtgcgc cggctcgtga gaaagctcga gcagcgcggc atcgccggcg tgtgcatcga
     6121 ggacaagcag tttccgaaaa ccaacagctt catcgacggc gagcgccagc cgctcgccga
     6181 gatcgacgag ttctgcggca agatcaaggc cggcaaggat tcgcagagcg atccggattt
     6241 ctcgatcgtc gcgcgcgtcg aggcgctgat cgccggctgg ggcatggacg aggcgctgcg
     6301 ccgcgcgaac gcgtatgcgc aggccggcgc cgatgcgatc ctgatccaca gcaagctgtc
     6361 gcgcccggac gagatcctgc agttcgcgcg cgaatggagc ggccgcgcgc cgctcgtgat
     6421 cgtgccgacc aagtactaca gcacgccgac cgacgtgttc cgccaggcgg gcatcagcac
     6481 cgtgatctgg gcgaaccatc tgatccgcgc gtccgcttcc gcgatgcagg cggtcgcccg
     6541 cgaaatccag gacagcgaaa cgctcgtcaa cgtcgaggaa cgcgtggcga gcgtcaacga
     6601 gatcttccgg ctgcaggacg ccgacgaata ctcggccgcc gagcgcatct acctgtcgtc
     6661 gagcgcgcgc gcgtcgagcg cggcgctcgt gctcgccgcg agccgcggca acgggctcga
     6721 ggccgtcacc gaggacaagc cgaaggtgat gctgccggtc gccggcaagc cgctgttgcg
     6781 ctggctcgtc gacggcttca agaagcaggg cgtgaacgac atcacggtcg tcggcggcta
     6841 ccgcgccgat gcgatcgaca cgtccggcgt gaagctcgtc gtcaacgagc ggcacgcgca
     6901 aacgggcgag ctcgcgtcgc tcgcctgcgc ggccgagcgt ctgacgggcg acaccatcat
     6961 ctcgtacggc gatctgctgt ttcgcagcta catcctgcgc gacctcgcgg aaagcgaggc
     7021 gcagttcagc gtcgtcgtcg attcgtcgca gacgcagccg tcgaaccaga gcgtgcgcga
     7081 tttcgcattc tgctcggccg ccgacgaccg cgggctgttc ggccagaaag cgtacctgcg
     7141 ccgcgtgtcg agcgacgcga gcgaggccgc gccgcacggg cgctggatcg gcctgctgaa
     7201 cgtgcgcggc gcgggcgtcg cgcggctgaa ggcgatgctc ggtacgctcc aggcgcgcga
     7261 cgatttcgat gcgctcgacc tgccggcgct gctgaacgcg ctcgtcgacg cgggcgagca
     7321 gatcgaagtg cagtacgtgc acggccattg gcgcggcgtc aacgatctcg acgacttccg
     7381 ccgcgcgggc gacttcgcgc acggccagac gccgtacgcg gagcagaacg cgggcagcgg
     7441 gagcgcacga tgatcgaagc cgcgcagttc gtcgaagcgg cgcgcgcgcg cggcttcgac
     7501 tggtacgcgg gcgtgccctg ctcgtatctg acgccgttca tcaattacgt gctgcaggac
     7561 ccggcgctcc attacgtatc ggcggccaac gaaggcgacg cggtcgcgct cgtcgcgggc
     7621 gcgacgctcg gcggccggcg cgggatcgcg atgatgcaga actcggggct cggcaacgcg
     7681 gtgagcccgc tcacgtcgct cacgtggacg ttcaggctgc cgcagctcct gatcgtcacg
     7741 tggcgcggcc agccgggcgt gcccgacgag ccgcagcacg cgctgatggg cccgatcacg
     7801 cccgcgatgc tcgacacgat ggaaattccg tgggagacgt tcccgacgca ggccgacgcg
     7861 atcggcccgg cgctcgatcg cgcgatcgcg cacatggacg cgacgggccg cccgtacgcg
     7921 ctcgtgatgc agaaaggcag cgtcgcgccg cacgcgctcg agcatgcctc gatgcccgag
     7981 cgccgcgcgc acgccgccgc gcgcgcgacg cccggcgcgg ccgcgccttc ggcatggccg
     8041 acgcgccatg acgcgctcgc gcggatcgtc gcgcgcacgc cggccgactc gacggtcgtg
     8101 ctcgcgtcga cgggcttctg cggccgcgag ctgtacgcgc tcgacgatcg cccgaaccag
     8161 ctctacatgg tcggctcgat gggctgcgtg acgccgctcg cgctcggcct cgcgctcgcg
     8221 cggccggacc tgaccgtcgt cgcgctcgac ggcgacggcg ccgcgctgat gcgcatgggc
     8281 gcgttcgcga cgctcggcgc gtacggcccg ccgaacctcg tgcatctgct gctcgacaac
     8341 ggcgcgcatg aatcgacggg cgggcaagcc acggtgtcgc aatacgtgtc gttcgcgggc
     8401 atcgcggccg catgcggcta cgcgacggcg atcgagggcg acgatctcgg cgtgctcgat
     8461 gcggcgctcg acgcggcgcg cgcgggcgag caggccgtcg agcacggcgg cgcgcacttc
     8521 gcgcgcctgt cgatccgcac gggcgtgccc gacggcctgc cccgcccgac ggtgacgccc
     8581 gtcgacgtga aaacgcgcct gatgcgccac atcggcgcga tgccggcctg acaaggagta
     8641 cgaagatgct gttgctgaat cccggtcccg tgacgctgac ggagcgtgtg cgccaaagcc
     8701 tgctgcagcc ggacctgtgc caccgcgaaa gcgaattctt cgatctgcag gacgaggcgc
     8761 gcgcgcggct cgtcgccgcg tacgcgctcg atccggccga atggagcgcg gtgctgatga
     8821 cgggctccgg cacggccgcg gtcgagagca tgatcgccgc gctcgtgccg gaaaacggca
     8881 agctgctcgt gatcgagaac ggcgtgtacg gcgagcggat cacgcagatc gcgacgcagt
     8941 accggatcgc gcacgacgtg ctgaaacacg actggatgca ggcgccggat ctcgcgcgcg
     9001 tcgccgagaa gctcgacgcg gatcgcgcga tcacgcatgt cgcggtgatc catcacgaaa
     9061 cgaccacggg ccgcctgaac gacctcgacg cgctcgccgc cgtgtgccgc gcgcgcggcg
     9121 tgcgcatgct cgtcgacggc gtgagcagct tcggcgcgga ggcgatcgat ttcgcgggcg
     9181 gcgacatcga cgcgctcgcc gcgaccgcga acaagtgcct gcacggcgtg ccgggcgcgg
     9241 cgttcgtgat cgtgcgccgc cgcgcgctcg cgagtgccgc gagccgcacc tactacctcg
     9301 atctcggccg gctcgcgaag ctgcaggacg cgcgcaacac gccgttcacg ccgtcggtgc
     9361 acgcgtacta cgcgctcgtc gaggcgctgc gcgagttcga cgaggcgggc ggctggcgcg
     9421 cgcgccacgc gcgctacgcg gcgctcgccg aacaggtgcg cgccggcctc gccgcgcgcg
     9481 gcatgccgct cgtgctgccg gacggcgaat cgtcggtcgt gctgcgcgcg taccggctgc
     9541 ccgccggcgt cgcgtacgag caactgcacg acggcctgaa agcgcgcggc ttcgtgatct
     9601 acgcgggcca gggcgggctg tcgagcgcgt tgttccgcgt gtcgacgatg ggcgcgatcg
     9661 agcccgcgga cgtcgagcgc ctcctcgacg gattcaccgc gctcgcgcgc tgatcccgcc
     9721 cggcggcgtc gcgctcgaat cgcgcggcgc cgctttcccg ggcccacgcc ccgctttgct
     9781 ccccgcgaaa acgcgccgcc gcgcgggccg cccgatcgcg cgcccgagtc cgcgtcgcgc
     9841 acgccgtgcg gcgcgccttc agcgcccgcg ctcgtatgcg gccctggcgg catccttgca
     9901 cggatcgaag aaccacgcgt gcgcggccag cacttcattg gtcagcgccg ggccggcgag
     9961 cgccggcgtg ccgacgccga acggcgcgcg cggatgatat tcgatcgtca gctcgacgtg
    10021 cttcgccgct tcggcaccac gcagttcggc cagcacgagc agcgccgcct cgaagccgcc
    10081 cgtcgcgggg ccggccgtat acagattgcc gtcgatcacg acctcgccgc cgccgacggg
    10141 ccgcgcgccg agctcggcga gcgcgtccag cacatgaaag ttggtcgtcg cgcggcggcc
    10201 gttcagcagg cccgccgcgc cgagcagcag cacgccgccg caaatgccga tcacatagcg
    10261 cgcgcggctc gcctgccggc gcacgaatgc aatcacctcg tcgtcggcga tcacgtcggc
    10321 cggcaccgcg ccgacgacga acgcgtcgag ctcgtccgga caatcggcga aggtcgtcgt
    10381 cgccgcgatc ggaaacggcg gcagcgcgga gatcggctcg cgcgtcttcc aaagcaggtg
    10441 cagctcggat cgcggcgcga agccgaacac ggcgtgcgcg ccgaacagat ccatcacggc
    10501 aacgccgggc gcgaggagaa agccggtttt cagggggcgt cgtgcggtgg cagacatcgg
    10561 tcgtcctttt cgaaaatgat gatgaaacac gaaatgcgcg aggcgacggt gcgcatcgcc
    10621 ccgcacgaca atcagcgtag cgcgcgaccg attggcgctt atgccaaact ggttgcagtt
    10681 tccgccaacg cctgaaccat gcgcctgatc gtctacatcc tcgtctttcc ggacctgaat
    10741 ctcctcgacc tgtcggggcc gctgcaggtg ctgtcgagcg ccaacgagct ctcgcgcgaa
    10801 gccggcgcgg acgcgccgta cgacatccgc gtcgtcgcgc gcggcgggcg cagcgtgcga
    10861 acctcgacgg gcatctcgct gtcgacgcag ccgctcgcgc ccatcgacgc gccggcggat
    10921 acggtgatcg tcgcgggcgg cgccggcgtg gacgcggccg cgcgctgcgc ggacacgctc
    10981 gcgtggctgc gcgcgcacgc gcggcaggcg cggcgcgtgg tgtcgatctg caacggcgcg
    11041 ttcctgctcg ccgcgtgcgg gctgctcgac ggccgccgcg cggtcacgca ctggcaatgc
    11101 tgcgacgcgc tcgcgcgacg ccatccccgg gtgcgcgtcg agcatgcgcc gatcttcgtg
    11161 caggacggcc cgatctggac gtccgcgggc gtcacggccg gcatcgatct gtgtctgcgc
    11221 ctcgtctcga acgactgcgg ccatacgctc gcgctcgcac tcgcgcggta tctcgtggtg
    11281 ttcctcgtgc ggcccggcag tcaggcgcaa ttcagcgaat cgatcgaaat gcagagcgcg
    11341 tccgggcagt tcgccgatct ccatgcgtgg attcgccgcc acttgcgcgc cgacctgtcg
    11401 gtgccgacgc tcgccgctcg cgtcaacatg agcgagcgca gcttcgtgcg ccattaccgg
    11461 aacgcgttcg gcacgacgcc cgcgaaggcg gtcgagcgca tccgcgtcga gaccgcgcgc
    11521 aacctgctcg gcgaaaccgc gctgcccgtc aagcaaatcg cgcagcgctg cggattcggc
    11581 agcgtcgcga cgctgcgcag gagcttcgcg cgcgcgttcg atacgtcgct gcacgagtat
    11641 cgcgagcggt ttcgccaagc gtgacgcgcg gcacggcgcg tggcgtgcac cccgatcgat
    11701 cggacctcga agcgatgcac ggcgcggcgc gccagcgaac gcccgcggcc gcgccgcgcg
    11761 ccggcgcatc cggcccgcgg gctgcgcaac tgcgcgctcg ccgcgatgga cagcgcatca
    11821 tgcttaggtt agcgtaacga tcgatcccgt cgcggcgcgc gtcgcgcgcg gcgcccagcc
    11881 ttccgcctat tgcgctgttt tcatgacgtc gaccttacaa tcccgtctgc ccggcctcgt
    11941 gcgcaatgcg ttgcgcccgg tgctcgatcc ctatcgccgc taccggcatg cgaagctgat
    12001 ccatgcggcg cgcgtcgcgc tgagcgtgct cgcgtcgatc gcgctgacga ccggcctgca
    12061 cgttccgcac ggcgaatggg cgacgatcac ggtgctgatc gtgatcggcg ggctccagca
    12121 tcacggcaac atccgcaaga aggccgccga gcgcgcgctc ggcacgctga tcggcgcgat
    12181 cgccggcctc tcgctgatcc tgctgcagac caccgtgcac ctgtcgccgc tcacgtttct
    12241 cgtgatgagc gtcgcgtgcg gcctctgcgc gtatcacgcg atcggcaagg ccggctacat
    12301 cgcgctgctg tccgcgatca cgatggtgat cgtcgcgggc cacggcgata acgagatcgc
    12361 cgacggcctc tggcgcgcgg tcaacgtgct ggtcggcatc gtgatcgcgc tcgcgttctc
    12421 gttcgcgctg ccgctgtatg cgacctactc gtggcgctac aagctcgccg atgcgctgcg
    12481 cggctgcgcg gccgtccatg cacgcatcgc gggcgagcgc tacgtgagcg acaacgagcg
    12541 cctgaaggac atggccgcgc tcaacgcgct gctcgtgcaa ctgcgttcgc tgatgccgtc
    12601 ggtatcgaag gaaatctccg tttcgatgcc gcagctcgag gcgattcagc ggagcctgcg
    12661 gctgtgcatg agcgcgctcg agatcctgtc gagccggcaa cccggcgagg acgacgccgc
    12721 cggcagacgc ttcgtccaga tccagatgaa ggcggacaac cggcggatcc aggagatgct
    12781 cgtcggcgcg gcgcgcgcgc tgaagttcgg cacgccgggc cggctcggcc cgctgcacgg
    12841 gccggccgcg gcggtcggcg agaacgtgcc gcccgcggac ttgtccggct atgtctcgct
    12901 gacggcgaaa ctctcgcacg aaatcgaaca gctcaggcag cgcctgcgcg acaccgcgcc
    12961 gcaatggaat atctgagcct ccgcgcgtcg cgcgacagcg gcggcacgcg ccgatggcgc
    13021 gcggcgcgaa gcgcccgcgc gggcgccgga agcacggtgc gtcgccgcgc cgatcgcggt
    13081 gacggcgagc gggcagccgg gcagccgggc agccgggcag ccgatcgtga agaagctcgg
    13141 cgggttcgcg ggcccgcccg gcgattcgcg ttgccgatcg tccgccccgc gccgcgagca
    13201 tcaccggcaa tgccggcagg atcacgccgc tcgcggcagg aagcggcggc cgtgcaaggc
    13261 atccgctctc gggcgcgatc gcgaacagcg gcaggccgac gccgctcaac cgtgccggcc
    13321 gttcgcgccg cgcgttcgca cgagcatgac gacggccatg aacgccgcgc tcgatgcggc
    13381 ggtgacgacg gccatcggcc gcgcggagcc gtcggacagc cggctcagca tcccgccgca
    13441 cccggccgtc atcgccatct gaatgaagaa gaacaatccg gaagcggtgc ccgcgagctt
    13501 cgcgaacggc tgcagcaccg cgaattggca cgccgggatc gaaacgccga ccgacaccat
    13561 gacgacgaac atcggcaacg cgatcgacca gacgctcggc ggcgcgaccg acgtcccgat
    13621 ccacagcgcg gccgcgccga ctagattgac aaaggcggcc gacgcgatga tcgcatcgat
    13681 tccgaaccgg ccgctcgccc ggcgaaacac gctcgagccg atcaggtagc cgagcaccgt
    13741 gatcccgaat atcgccgcat agacagcgcc ggaggcgcga agcgtgcgtt gaaacagcgc
    13801 agacgattcg gcgatgaacg gaaaatacgt gcaatagacg aagccgatcg cgagtgagta
    13861 acgcacgaac cggcggtcgc gaagcagcga caggtaagtc ttcgccaggc ccgcgccgcg
    13921 ttcgctcgcc gccgcgcgca cgcgggtctc cggcagaaag cgatgcacca tcagcgcggc
    13981 ggcgccgccg ccgaacgcga gcgacgcgaa aacgccgcgc cagccgagcc actgcgcgac
    14041 gacgtggccg gcaagcggcg cgacgacggg cgacaacgcc atgcccgccg atatccggct
    14101 gagcatcgcc gcttgcatcg ccgtaccgaa gcgttcgcgg acgatcacgc ggccgatcac
    14161 ggtgccgcag cagccgccca gcgcctggcc gatccgcgcg acgacgatgc cctgaacgct
    14221 cgtcgccgtc gcgcatgcga cgctcgcgcc gagatacacg agcatgccgg cgagcagcac
    14281 cggcctgcgc ccgtaacggt cggacagcgg cccggatagc agcatcgaca gtgcgtagcc
    14341 ggccatgtac atcgtgagcg tcagttgcat ctgcgcgtcg gtgccgtgaa gcgcgtccgc
    14401 catcgcgggc agcgacggca gatatgcgtc gatcgtcatg cgcggcaagc agacgacgag
    14461 catcagcagg cttagccagc cccggtcgga caatgtgttt gtttcggtcg tgttcattcg
    14521 gcgaggttct cgcggcctgg atcgattggc gcaagccgga atctaaacgc aatgtggtat
    14581 aagccgaaga accacttgtt cgaatattga atagaccact atggcgcgag gaaaaaccgc
    14641 gatcccgctc gacttgccgc gcccgcccgg cttgtccgtt cgccgcgcgc aatcgaaaca
    14701 ggactgcatc ggcgacgcgc tgcgcgacgc gatcctgcgc aagctgctgc cgggcggcag
    14761 cccgctgccg tccacccgaa cgctcgccgc gcgatggggc gtcgcgcgcg gcacggtgga
    14821 agccgcgttc gaccgcctct gcgcggaagg ctacatcgcc cgcgcgcacg gctcgggcac
    14881 gcgcgtgagc gccgtcgtcc ccgacgccta cctgtcgccg gcgcggcatc ctgcgaagcc
    14941 cgcgccccat gcgcgcggca agcctgccga cgcgctcgcg cgcgagcgcg cggccgaagc
    15001 ggacggttcg gtccgcgccg gcgtgccgtt cgtcgcgcgg ctggccgatc cgggcctgct
    15061 gccgatgcga acctggaagc ggcacatcgg cattggcctg tccgaagcga cgcacgccgc
    15121 gctctgcgcg ctgcccccgc aaggcgccga gccgctgcgc gcgcggatcg ccgactatct
    15181 cggccaatat cgcggcatcg catgcgacgc ggccgacatc ttcatcacga ccggcatccg
    15241 gcattcgctc gatctgatcg cccgcacgat cgccggcagc ggcagccgga tcgcaatcga
    15301 ggaccccggc taccgcaccg cgcggcgaat tttcgagctg gccggcgccg aatcgatctg
    15361 cgttgcggtc ggcccggaag gcatcgacac ccacgcattg agcgcgcatc gccgcgtcgc
    15421 tgccgcgtat gtgacacccg cgcatcagtc gccgctcggc gtgacgatgt cgatctcgcg
    15481 gcgtctcgac ctgctcgatt gggcacacgc gcggcgcacg tgggtgatcg aggacgacta
    15541 cgacggggag ttcggctatc agtcagcgcc gctgcccgcg ctgaaatcac tcgacgtgcg
    15601 caatcgcgtg atctactgcg gctcgttcaa caagacgctg ttttcggggc ttcgcgtcgg
    15661 cttcatggtg gtgccggcgg cgctacgcgc gccgatatcg gcgctcgtgc aggccgtcgg
    15721 gcgcccggtg ggcacgaccg agcagctcgc gctggcgagt ttcatcggca gcggcgattt
    15781 cgcgaagcat ctgcgcacga gccgccacgc gtacctgcaa cgccgcgatg cggtgctcga
    15841 gcagcttcgc cggtacgccg acggccagta tgcgatttcc ggcgaacaca ccgggtttca
    15901 tttcgtgctg tggctcgggc gcggaatcga cgaacgcacg ttcgccgaag aagcggcgaa
    15961 catcggtctc gcgctcgagc cgctgcgcgc gttctgcacg caagcggcgc tgcccgcagg
    16021 cgtcgtcgtc ggctattcgg cgctgagcgt cgcgcaagcg cgctacgcgg ggaaagagct
    16081 cggacaactg ctcgccggtg tgcggcgcga cgccgccgcg tgagcgttcg agtgtgtcgc
    16141 gagcggcgtg ttcggtgttc ggtgttcggt gttcggtgtt cggtgttcgg tgttcggtgt
    16201 tctgcgttct gcgttctgcg ttctgcgttc tgcgttctgc gttcaagcgt ccgatgtcgg
    16261 atgcccgacg tccaacgttt caacgatcac tcatcgctcg catcgagcga catctcgtct
    16321 cgcccccacg cgcaatatcc ggcgcgacat gcgcaacggc cgcgcgccgt cctcgaacag
    16381 tcaggatgcc gaatcgagcg gctccaccgt cacgccgacc gccagcacct gatcggcccc
    16441 gccgccgcga atgacgccgc gcaacggcgt cacgtccgcg tagtcgcggc cgatcgacag
    16501 catcacgtaa tcgtcgccgg gcgcgcgatc gttggtcgga tcgagcggca gccagccacc
    16561 gtcctcgggc cacgcgggat cgtagacctc gacccacgca tgcgatgcgt ccgcgccgat
    16621 caatcgcggc tgcccgggcg gcggctgcgt cagcagatag ccgctcacgt agcgcgcggc
    16681 aagcccgagc gagcgcagcg cgccgatcat cacgtgcgcg aaatcctggc acacgccctg
    16741 gcgcagcgcg agcgcatcga gcgcggtcgt gccgacgtcg gtgctgttcg gcgcatacgc
    16801 aaaatccgcg tggatgcggc gcatcagctc ccacgcggcc tgcacgagcg gccggcccgg
    16861 cgtgaagctc gccgccgcat aggcggcgag atcggagtgg catgcgacgt gcggcgaagc
    16921 gaacacgaat tcgctcgccg gatcgaacgg gcggccggca cgaaacgtca ggcgctcacg
    16981 caccgcttcc cacgcgctcg cgcagccgtc gcgcggcgcg gcgacggcgg gcggcggctc
    17041 gccgcgcttg cccgccgcca gcgcgggcgg cgtgacgcgc acgacgctgc ggctgcgcac
    17101 gaacagctcc tcgtgcggct ggttgagcgc gaacgaagcg cgctcgttgc cgaacgaatc
    17161 gatgtcgacg acgagccctt ccgcgcgcgg ctcgatctcg agcgagaact cgatcacgcg
    17221 ctgccgcggc gtctcgagcg ggcgcagacg cgcctgatgc tgcgcggatt cgacgcgcgc
    17281 cgcgtatcga tagcgcgtat catgcgtgac gcgcagcagc gcgccgcgcg ccggctcccc
    17341 gcgcgcggcc gccttgcgcg cgcgcgcctt cgcgttcgcc tgcggccgcg tcgtcatccc
    17401 catagcgacc tgcccgcatc gcgcacgtgg ctgaaatagc gctcgccgat ccggttcgac
    17461 acgtcccacg ccgccttgcc gcacgcttgc aggcgcgcga gcagcgccgc atgccggccg
    17521 tcgccgtccg tctcgcacag cacgtgcagc ggccagccgg cgatgtccgg aatcccgtcg
    17581 gcgagttccg acagcgcgta gccctcgctg cgctcgacct tcgacagccg gccccgcaac
    17641 gcctgcgcga cccacgcgag cgaacgcgga ttatcggtgt cgagcacgac gagcgacagc
    17701 agcggcgcga cgtcgaagca gcgctggaaa cgcgagcgga acgtgatgcc gctgtcgaac
    17761 agttcgagca cgagctcgaa accttcctgc ttgtggatcg cgccgccgtc gaacgcatgg
    17821 ccgagcacgc cgcacaggaa ctcgagccga tcgatctggc ggccgatcga cagcagacgc
    17881 cagccgtcgt cgcgcgtcat gttgtcggtc tgtgcgccgg tgatcgccga cagcagcaga
    17941 ttcagccgct cgaggcgctg cagcgcgtcg ttgccgagtt gctcctcggg ctcggcatcg
    18001 tcgccgcctt cgtcgaacag ttgcgtcgcc tcgtcgatca ggcgccactg ctcgcgcgac
    18061 aaccgctcgc gtatcgccgc cgccgcgcca cgcatcccga acaggcacga tgcgattccc
    18121 gtcgagcggt ccgcgcgagg cgtgagcgag cgcgtcagcg cctgctggaa cgcacgcggc
    18181 gcgtcgacgg ccggcggcgc gtcggcgggc agcaggccgt tgtcgcggca cagcgcgtcg
    18241 agcacatgca gatggacagg cgtctcgaca tcgtcctcgc cgcgcagccg ctcgagcgcc
    18301 gcgcgcgcga gccgcgtcag gttcgtcgca cgctccgtgt agcggccaag ccaaaacagg
    18361 ttctcggccg cgcggctcgc gatcgcgcgc gatcgctcct gcaagtcgtc cgggcccagg
    18421 tgcgtctgca acagcgtggt cggatcgacc gcgccttcgg tcatcaccca ggtgtcgacg
    18481 ctgctgccgc cgtgcggcat cggcgcgttg aacagctcgt cgcgcgtgcc gacccgcgca
    18541 aggccgcccg gcagcacgcg ccatgagcgc gcgccgtccg cgagcgcgaa cacgcgaagc
    18601 agcaacggcc gcggcacgat ccgcgcgccg ccgtcgccca tgcccgcgcc ggccgcccag
    18661 gtaggcgcct gcgatagcgg caggtccgcc tgaatcgtgt aatgcgcggg ttgcgcggcg
    18721 atccgcgcgc gccaatcggc gagctgccgg ggcgaaagcc gcgcgccgat caccggctcg
    18781 aacgcgccgc ccgcctgcac gctcgcgggg aacgtcggct tcacgatgcc gcgcgcgagc
    18841 agcggcagcg cctcgtcgca cgccgcctgc tcgccgcacc accacgaatg caccgcgggc
    18901 agcgtcagcg tctcgtcgag cagggcctgc gcgaggcgcg gcaagaagcc gagaatgccg
    18961 ggcgattcga gaaagcccga gcccggcagg ttcgcgagca gcacgttgcc cgcgcgcacc
    19021 gcctgcatca gccccggcac gccgagcagc gaatccgggc gcagctcgag cggatcgagc
    19081 cattcgtcgt cgacgcgccg caggattcca tgcaccggtt cgagcccgcg cagcgtcttc
    19141 agatagacgc gctggtcgcg cgcggtcagg tcgccgcctt cgacgagcgt gaggcccagg
    19201 tagcgcgcga ggtatgcatg ctcgaaatag gtcgccgcat gcgggcccgg cgtcagcagc
    19261 acgatgcgcg agttcttccg cgcggggctc agcgcctgca tgctctgcag cagcgcgcga
    19321 tagctcgccg cgagccgctg cacgtgcagg ccgcgaaacg cgcgcggaaa gagcctcgac
    19381 acgattagcc ggttctccag cagatagccg agccccgccg ggccctgcgt gtgctgcgcc
    19441 atcagccgcc acgcgccgtc cggcccgcgc gcgagatcga acgcggcgac gtgcagccac
    19501 gtgccgcccg gcgcttgcgc gccgcacatc ggccgcagat agcccggatg cccggtgacg
    19561 agcgcgggcg gcaacagccc gcggcgcagg atcgtctgtt ctccgtagag atcggcgagg
    19621 atcgcattgc tcaggcgcac gcgctgcagc acgccccgct cgatcgccgc ccagtcgtcg
    19681 ggcgcgatga tgagcggcag caggtcgagc gaccagggcc gcaccgcgcc gccgcccgcc
    19741 gcgcgctcgt gcggatgata ggcgagcccg ttctcgcgca tccggcgctg cagcgcgtcg
    19801 gcgcggcggt cgagatcggc gaagccgaca ctgccgagct gcgtgaagaa tgcgcgccac
    19861 gcgggcgcga gagacgcgct cgacaacgca gccgcgccgc cgcgcaactc gtcgtaacgg
    19921 cccgtgaccg caggcgcggc gagcgccgcg ccgaactcgg ccgcgtcctg ctgcgaaccc
    19981 gtatcgaata gcgtctgcat cgcgtcggcg gtcagatcgt cgtcagagga aagtgaaagc
    20041 acgattcgat tcttcaagga cggcggcgcc gagccgccgg ggcggcgcac gccgcccgtc
    20101 gatgtcgaat cctaacattg ccgcacgccg caagcgcgac gtcgcccgct cgacgcgcga
    20161 cgcatcggtc ccgccgccgg cgcggccgcc gcggttgggc gacgagcacg gccgccgcgc
    20221 cgcatccgct cacccatgcc gcaaatccag cgtgaacgga aattcgcggc tcggcgcggc
    20281 cggctcgacc gtcatcgcgc ccggcgtgtg tcccatcgac acgaagcgcg cgagccgccg
    20341 gctctcggct tcgtaagcgt tcacggggaa cgtgtcgtag tggcggccgc ccggatgcgc
    20401 gacgtgatac cggcagccgc cgagcgagcg ccgcatccat gtatcgacga tgtcgaacgt
    20461 gagcggcgcg tgtacgccga tcgtcggatg cagcgccgaa ggcggcgccc atgccttgta
    20521 gcggacgccc gcgacgtact cgccggcggt gcccgtcggc tgcagcggca gcgcgcggcc
    20581 gttgacggtc acgacgtagc ggctgtcgtt cagcccgctc acccggactt cgagccgctc
    20641 gagcgacgaa tcgacgtagc gcacggtgcc gccgatcgcc ccctcctcgc ccatcacgtg
    20701 ccacggctcg agcgcgccgc gcagcgcgag cgcgacgccg cgcgcggcga tctgcccgaa
    20761 cagcggaaaa cggaattcga agtgcggcgc gaaccacgcc gcgtcgaacc cgaagcccgc
    20821 ttcgcgcagc tcggtcagca cgtcgtcgaa atccatcctg acgaagctcg gcagcaggaa
    20881 gcgatcgtgc agcgcggtgc cccagcgcgc gagcggcgcc gtgtacggcg cgcgccagaa
    20941 gcgcgcgatc agcgcgcgca acagcaattg ctggacgatg ctcattcgcg cgtgcggcgg
    21001 catttcgaac gcgcgcagct cgagcaggcc gaggcgcccc gtcgccgaat ccggcgaata
    21061 gagcttgtcg atgcagaatt cgctgcgatg cgtgttgccc gtcacgtcga tcagcagatt
    21121 gcg
//
