LOCUS       NZ_CP009288            27241 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Paenibacillus durus strain DSM 1735 chromosome, complete genome.
ACCESSION   NZ_CP009288
VERSION     NZ_CP009288.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus durus (Paenibacillus azotofixans)
  ORGANISM  Paenibacillus durus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1  (bases 1 to 6038347)
  AUTHORS   den Bakker,H.C., Tsai,Y.-C., Martin,N., Korlach,J. and Wiedmann,M.
  TITLE     Comparative genomics of the Paenibacillus odorifer group
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6038347)
  AUTHORS   den Bakker,H.C., Tsai,Y.-C., Martin,N., Korlach,J. and Wiedmann,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2014) Food Science, Cornell University, Stocking
            Hall, Ithaca, NY 14853, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method :: HGAP, Quiver (SMRT analysis) v. 2.2
            Coverage                          :: 98x
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000756615.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:15:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,487
            CDSs (total)                      :: 5,373
            Genes (coding)                    :: 5,301
            CDSs (with protein)               :: 5,301
            Genes (RNA)                       :: 114
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 26 of 72
            Pseudo Genes (incomplete)         :: 54 of 72
            Pseudo Genes (internal stop)      :: 8 of 72
            Pseudo Genes (multiple problems)  :: 15 of 72
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:59:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5689260
            Orig. end                         :: 5716501
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009288.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27241
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="13"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..27241
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27241
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17241]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17241
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    518..533
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.26"
                     /tool="antismash"
     misc_feature    complement(740..758)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.0"
                     /tool="antismash"
     CDS             complement(1154..1390)
                     /gene="allorf_5690414_5690650"
                     /locus_tag="allorf_5690414_5690650"
                     /protein_id="allorf_5690414_5690650"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNLIITLVTNLYDYFYRNQEIQHDMVDKLIRQVYRGGHSPYKGFL
                     HHVNEGKRRIRILIKRKKMVLDVRLIAQRCMLK"
     CDS_motif       complement(1280..1390)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNLIITLVTNLYDYFYRNQEIQHDMVDKLIRQVYRGG"
                     /locus_tag="allorf_5690414_5690650_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1154..1279)
                     /prepeptide="core"
                     /locus_tag="allorf_5690414_5690650_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="4965.1"
                     /monoisotopic_mass="4961.9"
                     /core_sequence="HSPYKGFLHHVNEGKRRIRILIKRKKMVLDVRLIAQRCMLK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNLIITLVTNLYDYFYRNQEIQHDMVDKLIRQVYRGG"
                     /leader_location="[1279:1390](-)"
     misc_feature    1166..1179
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.62"
                     /tool="antismash"
     misc_feature    complement(1571..1588)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            complement(1700..2548)
                     /locus_tag="PDUR_RS25110"
                     /old_locus_tag="PDUR_26120"
     CDS             complement(1700..2548)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008592392.1"
                     /locus_tag="PDUR_RS25110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26120"
                     /product="transglutaminase family protein"
                     /protein_id="WP_042208656.1"
                     /transl_table=11
                     /translation="MNYEIMHTNTFKYETQVDQSLNTIRLKPLTDEVQRLLMYRAEITP
                     ASLTKEYTDLWGNQVETFFIPEKHNLLEVKTTSVVSIQRGSFIHEIRYLKRMQDIFHSQ
                     QFRQHYLSYLNETDYTLLHPEQLSEVKRGLGEMDNPVQYALRVMRYVYETFTYCGEVTS
                     VDTLARQAFELKKGVCQDLAHVMIGILRACRIPARYVSGYLYVGEDSALKGDAATHAWV
                     EVMVPGIGWVGLDPTNNVEALDNHIRVGTGRDYADVSPLQGVYRGGSSTLEVGVSVTLL
                     E"
     gene            complement(2713..4248)
                     /locus_tag="PDUR_RS25115"
                     /old_locus_tag="PDUR_26125"
     CDS             complement(2713..4248)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012475.5"
                     /locus_tag="PDUR_RS25115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26125"
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="WP_081949968.1"
                     /transl_table=11
                     /translation="MSVKFISKKVKGVLYAVLVGLLFTFGFVGSKEAFADSELNRPEYH
                     ITPQAEWMNDVQRPLYINGQHHLYYLYNDDFSWGGNGTEWAHAVSTDLVHWERKPVAIE
                     KYKTPYGDPWTGSTVIDENNTAGFGNNAVIALVTMPFEGQSTHLWYSTDGGNSFKHYNI
                     VQHNPTGSADFRDPKIIWHEPTKKWVMLLAERDKVGIYTSSNLKDWEYASSFVRQDIGI
                     VECPDLFQLNVDDNSDTKKWVLMVGGNGFNYGVTTGSSYFVGDFDGREFHAETPVKWLE
                     RGADSYTGVTWDAPYTNGNYRYFISWMNNWNYARKLPWDTFNGNTSIVREMRLKTTTEG
                     LKLVQKPVWNLLDSFPTILDIKEEDIYTGQENIFKDFHGLSYSIEAQIDVGDLTEGKFG
                     FSVRDGDGQHADLTYDKSINEFVFNRENSRIKIDVEEFKRPQRVIVKPKDGKIKLDILV
                     DRGAVEVFINDGEYVLSNLVLNDLSSDGLRLWADGHVHLEYLKLRTSNKFTIL"
     CDS             4367..4561
                     /gene="allorf_5693627_5693821"
                     /locus_tag="allorf_5693627_5693821"
                     /protein_id="allorf_5693627_5693821"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MYISSNGDIHGCAGLVENWVFVRKIRSKTCSGYEVKLWIYRSERK
                     PRDRGEPGGQSGFRSPIIC"
     CDS_motif       4367..4528
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MYISSNGDIHGCAGLVENWVFVRKIRSKTCSGYEVKLWIYRSERKPRDRGEPGG"
                     /locus_tag="allorf_5693627_5693821_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4529..4561
                     /prepeptide="core"
                     /locus_tag="allorf_5693627_5693821_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.90"
                     /molecular_weight="1071.2"
                     /monoisotopic_mass="1070.6"
                     /core_sequence="QSGFRSPIIC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MYISSNGDIHGCAGLVENWVFVRKIRSKTCSGYEVKLWIYR
                     SERKPRDRGEPGG"
                     /leader_location="[4366:4528](+)"
                     /alternative_weights="1089.3"
     gene            4678..5271
                     /locus_tag="PDUR_RS25120"
                     /old_locus_tag="PDUR_26130"
     CDS             4678..5271
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024908.5"
                     /locus_tag="PDUR_RS25120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26130"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_081949662.1"
                     /transl_table=11
                     /translation="MQKPPYQVAQKLMILQAMESGQISIRAAAKIYGIGRTTLAEWQPR
                     YEVYGYAGLETRTRNRRYSAEFKLQAVLDYLSGSLSQSQIIDKYQIVSRTQLRNWVKTY
                     NDHSSIKIYSGGTKAMTKGRTTTWQERIDIVLYCLAQQHDYQKTADHFQVSYQQVYQWV
                     KKYERGGEDALRDGRGGEKRNPKRPPKRNTTSSQ"
     gene            5268..5642
                     /locus_tag="PDUR_RS28365"
     CDS             5268..5642
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024673.5"
                     /locus_tag="PDUR_RS28365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_081949664.1"
                     /transl_table=11
                     /translation="MKKLEYENERLRAENAFFKKLQELESRPTLSAHRQERIYLAIQAV
                     HEQEAFPVQLLCDLAGISRSSYYKWRAHRPSARERENRKLTDALISLYEQVGGIYGYRR
                     LTLHLRRQTEQALNPKRIRR"
     gene            5642..5770
                     /locus_tag="PDUR_RS30155"
     CDS             5642..5770
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PDUR_RS30155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269079197.1"
                     /transl_table=11
                     /translation="MKIRGIQSVIRRARKAYARSTPQQVAENLLNRKFHASAPNKK"
     gene            6024..6233
                     /locus_tag="PDUR_RS30370"
     CDS             6024..6233
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025063.5"
                     /locus_tag="PDUR_RS30370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_367888851.1"
                     /transl_table=11
                     /translation="MSRVGRCIDNGPMKSFWGTLKCERYYLHSYSTFEELQHDMEDYIH
                     FYNNERLQAKLNGLIPMEFRTKAA"
     gene            complement(6299..6487)
                     /locus_tag="PDUR_RS25130"
                     /old_locus_tag="PDUR_26140"
     CDS             complement(6299..6487)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186368.1"
                     /locus_tag="PDUR_RS25130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26140"
                     /product="DUF4177 domain-containing protein"
                     /protein_id="WP_036593000.1"
                     /transl_table=11
                     /translation="MYKYEFVSISVGTLSGKLKEDYRQVIEQHSARGWKLHSIVPMPVL
                     AGGQVSTLELIFERFEQ"
     gene            complement(6504..7841)
                     /locus_tag="PDUR_RS25135"
     CDS             complement(6504..7841)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.5"
                     /locus_tag="PDUR_RS25135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_051499770.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.5e-35, bitscore:
                     119.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKKPLASLLLLMVCALLAATPFRTVSAVDVGNSQSETIFVLLD
                     RPHQMKTIDSLLSKSQLTADKIQEIGFLKLQGTSEELDRWLKKSASEVDFSWYKDPGES
                     AEAKMLQNRNYWDLHGMEELNAYLWYAEAQTNHYTTYDIQEGNPKVKIALLDSGVDLAN
                     EHFGQTILTVDSWNYVDGNNSVQDENGHGTQVAGVLSLLAPKISIVPYKIMNNGGGNSF
                     ALLSAIVRAANDGNQVINISAGSYIRLDDAGRILREAYQRAVDYADKMNAIIVASAGNR
                     GTGDKSNAASNEIHAPSMLEHVISVGAVMKSNRLAPYSNYGPYIDFVAYGGYFGDDFDT
                     TGNVNVTDLMLTAFPKSLPNTALDIMLNIPQGYSLSFGTSLAAPQVSATAALLISNYYD
                     RHHHYPQADNIFRLLKQSAVDLGDPGRDDKFGYGEVIVDQALKLKN"
     gene            complement(7860..10010)
                     /locus_tag="PDUR_RS25140"
                     /old_locus_tag="PDUR_26150"
     CDS             complement(7860..10010)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186373.1"
                     /locus_tag="PDUR_RS25140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26150"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_036592999.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-41, bitscore:
                     140.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFINRTPFVEQMQQTECGICCISMVAGKYNAHKTLRELRNMAGIG
                     RDGVTLYTMRNTAVRLGFKAKVFRAELHQLSQLRLPVIAHWNENHYVVIDKINKNSIKI
                     IDPAVGRQTISYEEFQKSYNFIVLEMTPTEQVVPQKRVSVWGKFLKYLMEIPKKVTIVI
                     IIAIIYQLGTLGMPILVQYLIDNIITANKFQLLSIFMVSVIFLTIVQGFVQFFRGKFII
                     VLNNTLDKRMMQHFFSHILKLPYQFFQLRSFGDLLFRASSLRIIREMLSSKLVLGLLDF
                     SAITFITIYMLNKSLVLTSLVVGLSLLNVLMLILTKRRLKEVNQDEILKTSQLQSYQTE
                     FLYGIFGIKTAGIEKETYHRWASFLDQLIQAYKNKEGFMNMIASLSGTLQMMSPLLVLW
                     IGAMLVFNNQLSLGELIAFYSLSNNFFSMSGSIVQTINSFMLTGAYLERVQDVLDEPLE
                     HTDDDKESITEFKGNIRLDNVSFRYSEHSDWVVKDISLDIVSGQKIAIVGQSGAGKSTL
                     AKLILGLYMPSNGKVYFDGKDIRELNLSALRKQIGVVPQDVSLFNRSIKDNISLYKEDV
                     SLEEIQSVTKMAEIYEDIVRMPMGFNTMVSELGMNISGGQRQRIALARALLNKPSVILL
                     DEATSSLDHQNEKRIDHFLRRLKCTRVVIAHKLTTIMDSDLIIVMENGEITALGTHHDL
                     LKKSEFYAEFYAKFQEHAYSPV"
     gene            complement(10001..13111)
                     /locus_tag="PDUR_RS25145"
     CDS             complement(10001..13111)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="PDUR_RS25145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_081949668.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-100, bitscore:
                     335.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-57, bitscore:
                     193.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNKLQSAFKQSAYLRELAPFSTEMENVDEGTVNYNISEKALYNK
                     LSSLRLTKQNYEHIIRNYPQLIENHLPEWVQVLRKITAYDPKAVSHIKYELPHKSFVTY
                     FTPFILYVQNEMEDFFKSLSRENSLVKTKIDIHQYMECVISIIHSDIDKLSTKMLIAEL
                     NIARMEGSLKGSDGEERYIYFVEQYLGDSENFAGIFEVYPVLGRVLCERLVQLIEIHKT
                     LVKHFLMDYETIEETFGFRSPRLTGVKGDLGDSHKKGRSVEIIETTAGKLVYKPRSLAV
                     DSHFTEIVAWVNASGVKHSLRAAKVLDREQYGWQEFIQYDDCIDEAQIQRFFYRQGMNV
                     ALLYAFRSVDFHNENLIAAGEYPILIDLETLFDNQIDLFQNQNQLHITALELKNSVLSS
                     MMLPVKFNHDQALDYDLSGIAGRGGQKSKRNKGYTISNFGTDAMAFVETELVTKNKLNV
                     PAINGQDIQIFDYKEYLLEGFRDTYRSIESHKFEFESLLNMFSKDEVRHVFRPTHVYGK
                     FLEASTHPKYLQRGIDREGLFDYMWSITEWSELANVFVRSEINDLVVHDIPYFTFLVGG
                     KHLYNSAGKEYRDFYKESSLALTKSRIRSFSEADRLKQERYISLSLATLIDNVWNGISE
                     QPAELPTPVHLRDEIVTIADGMLAKALYDKKGRSPFWISTSVGNEDDIFLSPLPPGVYD
                     GIGGIAIFYAQLGVFLKSAEYERTAKSILNVLMGEEKFWLANMDSTSAFFGIGAFVYVY
                     SYLGCLWNDSSLLHRAVGLLPAIEKLLPLEEEIDIIRGHAGLLKVLANLYRAYPADEVI
                     RVLQILSERYLQQIRNTVIHSDSGRSAGFAHGISGIAFSLAHVYCVLPSSDIQRTIMKL
                     VEIENRFYVGSERKWLDLRENKHALAANYWCHGSYGILLARAHIHALLPSFPAELLMID
                     RLLNDLSETEGATGHSMCHGELGNRNVLLDVHRLLQGAKLAGEAEWMQLNKTPDRPWRT
                     GMHPDIESLGLFTGISGIAFGMLRLLDPEIPSILALDIPLNEVDVCS"
     CDS             complement(13115..13303)
                     /gene="allorf_5702375_5702563"
                     /locus_tag="allorf_5702375_5702563"
                     /protein_id="allorf_5702375_5702563"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKRPAGRGLTLTPSARVLCCIKLVPQPISLESKGRAAAEPLLSGC
                     HEVCFHGSPFLLIYDKG"
     CDS_motif       complement(13190..13303)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKRPAGRGLTLTPSARVLCCIKLVPQPISLESKGRAAA"
                     /locus_tag="allorf_5702375_5702563_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13115..13189)
                     /prepeptide="core"
                     /locus_tag="allorf_5702375_5702563_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="2626.0"
                     /monoisotopic_mass="2624.3"
                     /core_sequence="EPLLSGCHEVCFHGSPFLLIYDKG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKRPAGRGLTLTPSARVLCCIKLVPQPISLESKGRAAA"
                     /leader_location="[13189:13303](-)"
     gene            complement(13377..13598)
                     /locus_tag="PDUR_RS29295"
     CDS             complement(13377..13598)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186379.1"
                     /locus_tag="PDUR_RS29295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_081949670.1"
                     /transl_table=11
                     /translation="MISMKNSKIRNEFLKTSKTVGVVTEEELKMLTGGAGDVNPETTIL
                     TTSSWTCITAGVTVSASLCPTTKCTSQC"
     CDS_motif       complement(13497..13598)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MISMKNSKIRNEFLKTSKTVGVVTEEELKMLTGG"
                     /locus_tag="PDUR_RS29295_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13377..13496)
                     /prepeptide="core"
                     /locus_tag="PDUR_RS29295_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="0.50"
                     /molecular_weight="3679.1"
                     /monoisotopic_mass="3676.8"
                     /core_sequence="AGDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MISMKNSKIRNEFLKTSKTVGVVTEEELKMLTGG"
                     /leader_location="[13496:13598](-)"
                     /alternative_weights="3697.1"
                     /alternative_weights="3715.2"
                     /alternative_weights="3733.2"
                     /alternative_weights="3751.2"
                     /alternative_weights="3769.2"
                     /alternative_weights="3787.2"
                     /alternative_weights="3805.3"
                     /alternative_weights="3823.3"
                     /alternative_weights="3841.3"
                     /alternative_weights="3859.3"
                     /alternative_weights="3877.3"
     misc_feature    13699..13712
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            13731..13973
                     /locus_tag="PDUR_RS25150"
                     /old_locus_tag="PDUR_26160"
     CDS             13731..13973
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186381.1"
                     /locus_tag="PDUR_RS25150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26160"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_036592998.1"
                     /sec_met_domain="mature_ha (E-value: 2.1e-09, bitscore:
                     35.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDKALVTAWKNPMARKGLGAIHHPSGDVLAELKEEDLQDFTGGF
                     DTNTLTTSTSILISMTLGNNGWVCTATKECMPSCN"
     CDS_motif       13731..13862
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MYDKALVTAWKNPMARKGLGAIHHPSGDVLAELKEEDLQDFTGG"
                     /locus_tag="PDUR_RS25150_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13863..13973
                     /prepeptide="core"
                     /locus_tag="PDUR_RS25150_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.50"
                     /molecular_weight="3640.1"
                     /monoisotopic_mass="3637.7"
                     /core_sequence="FDTNTLTTSTSILISMTLGNNGWVCTATKECMPSCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MYDKALVTAWKNPMARKGLGAIHHPSGDVLAELKEEDLQDF
                     TGG"
                     /leader_location="[13730:13862](+)"
                     /alternative_weights="3658.1"
                     /alternative_weights="3676.2"
                     /alternative_weights="3694.2"
                     /alternative_weights="3712.2"
                     /alternative_weights="3730.2"
                     /alternative_weights="3748.2"
                     /alternative_weights="3766.3"
                     /alternative_weights="3784.3"
                     /alternative_weights="3802.3"
     gene            14098..17241
                     /locus_tag="PDUR_RS25155"
     CDS             14098..17241
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017474093.1"
                     /locus_tag="PDUR_RS25155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_042208659.1"
                     /sec_met_domain="DUF4135 (E-value: 1.9e-106, bitscore:
                     354.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9e-70, bitscore:
                     233.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKYYVYSERELVTDAASNAEVQEKTSYWRTLFNDDQDWLNKSI
                     SIFTNDDVESIAKSSLSASIELNTSSSYDHDHWLNIKYRFFATYSESGFTTDNTIQNPL
                     FFDTLLMRFAYVADLELASHKVALPASIKDKTLYHLKKTLLEIGYQTLILELNVLRVQE
                     QLTGGSPEERYHSFNRLFLNDISYIHSFFDEYPVLLRLMCTKTAYWVQNVAELLHRLSN
                     DAEQISQQFGVSGDIIDLDLGLGDSHDKGKMVAIITFANGRVVYKPRSHEVDIKFQQIL
                     SWVNLRQPPRKLATYTILNCGTYGWSNFVVYRECDQLEQLNDYYIRLGQILAILYSIDA
                     VDFHHENIIACKDHPILIDLESIFHQSKQNEVSMDTAISKARYILTRSVNSTGILPFNS
                     YYEKKDSNRVLDLSGLSGKEAQEAPFKAYQIKQSFRDDMHLAKDSFQIQEAQNVPKLNG
                     EPVEILEYLNFIVDGFRQVYQLIQTNKASYLALLTIFETCPVRTIIRPTAVYAQLLQRS
                     YHPDFLRDAVDREVFLCRLEKFINEDTNYDVARSELLDLLNGDIPYFLSSPATTHLEAA
                     NQTFVAEYFEKAALTRVREKIDSLSDTDLGEQLHVIRMSILASFNAKHHKDTLILSKET
                     GNISLEAVTVTDILNCSKRVGEYVLDQRITAEGSEDISWISTMIKGIDEVSWTISPVNL
                     DFYNGVAGIGFYLSYLGKIFPEHNVFQEVTIRCVNTVIDSLNELQKQDMDWTPYMEVGG
                     FTGISSYLYFLQHASVNLHRPEWFQAVLQFLPLLEELIEKDEQFDVTSGSAGALMVFLS
                     LYEQQQEKELLVLAERCVQHLQRNATAMSTGIAWRDPYHQKFYTGFAHGSSGILAALAK
                     FNKVMDAGSIKRTIHEGLLFERSMYVSKEKNWKSIGRDQLSVAWCHGAPGILLSRHILQ
                     ESGYHDNDLESEIDAGLETTIKLGLDNNRSFCHGDFGQLEILSNFSSQSSDIQAVTSDL
                     SGRLFEYYNKHDMTGGVSRGVEAVGLMLGWSGVGFGLLQQALPGNLPQILHLSPPVRS"
     gene            complement(17330..18274)
                     /locus_tag="PDUR_RS25160"
                     /old_locus_tag="PDUR_26170"
     CDS             complement(17330..18274)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.5"
                     /locus_tag="PDUR_RS25160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26170"
                     /product="ABC transporter permease"
                     /protein_id="WP_036592997.1"
                     /transl_table=11
                     /translation="MRLLGNELYRFYKNRNTWLITLLLFFITVAYTLLVSFSRPNTLAD
                     SGNWRSGVENQIQEDKKQMAALSPSMPMHRFLSEQLVVNQYRLDHDLPPTSKYDALTLI
                     NELRPVTTLITLVAIVLAANAIAAEHAKGTIKFVITSPIRRGTYLLLKYASVVINILLL
                     FMAFMMLASLLGYVWLGTGGSNYYLAYQNGAIVKMSMMTYLCLKYLATLANIVMVATLA
                     FAVSVLFRNAILAVGVSLLLYFTGTTMTQFFAMKFGWIKYLIFANYDLSAYLDGRPVVE
                     SMTLSFSLTMMAVYFVAFLSISYVTFTRRDITT"
     gene            complement(18274..19206)
                     /locus_tag="PDUR_RS25165"
                     /old_locus_tag="PDUR_26175"
     CDS             complement(18274..19206)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186353.1"
                     /locus_tag="PDUR_RS25165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26175"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_233277433.1"
                     /transl_table=11
                     /translation="MGGIKLDFLSINQVSKRIGGKNIIKNVSLSVPKGKIFGLLGPNGA
                     GKTTLIKMMVGIMKMSSGDIRIGGSSIQSEFKDAIRKVGAVIENPSFYGEMTGFQNLRY
                     ISAFHMKPNKVNIERQLEAFGLSDSANKRVKKYSLGMKQRLGLAVSLLHNPDLVILDEP
                     TNGMDPQGIIDLRRILRGLAEKHEKTVFLSSHLLSEVELLCDYYGVMNDGELLEIKENG
                     RAANEFRYTLSFDSTCIKRAMQLLTEAGYQVKRNEAAYELSFVLPEEKIMIVINMLNHH
                     QIEVLNMKQARWTLEEDFIALLNANKGAS"
     gene            complement(19234..19527)
                     /locus_tag="PDUR_RS25170"
                     /old_locus_tag="PDUR_26180"
     CDS             complement(19234..19527)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186361.1"
                     /locus_tag="PDUR_RS25170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26180"
                     /product="hypothetical protein"
                     /protein_id="WP_036592996.1"
                     /transl_table=11
                     /translation="MNSLTLMNSIFAVLGFLAFVSIMILSIAGVRDERGLYIFNKFFKY
                     MFFLLSASFSLVILISSWVDMGYELYRNMVTLLFSLSFVIGFFIWIGLWKRN"
     gene            complement(19536..19751)
                     /locus_tag="PDUR_RS25175"
                     /old_locus_tag="PDUR_26185"
     CDS             complement(19536..19751)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892393.1"
                     /locus_tag="PDUR_RS25175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26185"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_052410396.1"
                     /transl_table=11
                     /translation="MGDGDSYLKHHILELRTERGWTQQQLADALQVSRQTVISIERNKY
                     MPSLKLAFRIAEVFQKSIYEVFDYER"
     misc_feature    complement(19765..19774)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    complement(19775..19791)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.02"
                     /tool="antismash"
     misc_feature    19918..19931
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.49"
                     /tool="antismash"
     gene            19993..20316
                     /locus_tag="PDUR_RS29950"
     CDS             19993..20316
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PDUR_RS29950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_233277434.1"
                     /transl_table=11
                     /translation="MYIHDSMDQLHLPMDLEEDFPPNHFVRVVNDMVNRTCDKIFAAAH
                     PGAGRHSYHPKMLTKIILYAYISGSTLPVKSPRLCGKPSRSCGWPDASTRTSAPLTGSA
                     ASG"
     gene            20250..20630
                     /locus_tag="PDUR_RS29955"
                     /old_locus_tag="PDUR_26195"
     CDS             20250..20630
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017416.5"
                     /locus_tag="PDUR_RS29955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26195"
                     /product="transposase"
                     /protein_id="WP_042208662.1"
                     /transl_table=11
                     /translation="MWLAGCQHPDFRTINRFRSKRMKDVLESLFTALLELIIQGGYVKV
                     DYYFVDGTKIEANANRYTFVWRKVVVRYKMKLQEKVRVLFQTIEEQEQQENLAHEGADL
                     AELGGIRFTKQRSVGTGPRISR"
     gene            20756..21139
                     /locus_tag="PDUR_RS29960"
                     /old_locus_tag="PDUR_26200"
     CDS             20756..21139
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013752.5"
                     /locus_tag="PDUR_RS29960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26200"
                     /product="transposase"
                     /protein_id="WP_042208663.1"
                     /transl_table=11
                     /translation="MKNGQLKPGYNVQAGTESQFIVGYSVHQRPTDTRCLIPHLKQLQK
                     RLGQLPKTVVADAGYGGEENYAYLEEENCEALVNTIRSTGKRTSPGKPIPGSWRTGHMK
                     NRTTSGFAEMGESWILCGKAGAS"
     gene            21249..21356
                     /locus_tag="PDUR_RS30375"
     CDS             21249..21356
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025126.5"
                     /locus_tag="PDUR_RS30375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_407944321.1"
                     /transl_table=11
                     /translation="MAYLRYKEQAREKLRSEEGRALSARRMAEVERVFG"
     gene            complement(21613..22467)
                     /locus_tag="PDUR_RS25200"
                     /old_locus_tag="PDUR_26210"
     CDS             complement(21613..22467)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007784757.1"
                     /locus_tag="PDUR_RS25200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26210"
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_042208664.1"
                     /transl_table=11
                     /translation="MARKRSLWFAAVIVATGILAGCGSQNGNGEAAAPQTSAAASEAPK
                     EVTIKVGASAVPHAEILEFIKPKLKEEGVNLEVVTLDDDGQLNPALQEKQIDANYFQHV
                     PYLDSVKGEKGYDFVVTAKVHVEPIGFYSEKLKSKDEIPHGAKIGIPNNPSNEYRALVL
                     LQQQGLIKLKDGLTTYEATPKDIVDNPHNLEFVEADAATLPRSLPDLDGAIINTNLVLD
                     AKIDPKTALFREDANSPYANVVVVRKGDENREEIKKLDAALTSPDVKKFIEDKYGVAVV
                     PAF"
     gene            complement(22586..23254)
                     /locus_tag="PDUR_RS25205"
                     /old_locus_tag="PDUR_26215"
     CDS             complement(22586..23254)
                     /EC_number="7.4.2.11"
                     /GO_function="GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005831198.1"
                     /locus_tag="PDUR_RS25205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26215"
                     /product="methionine ABC transporter permease"
                     /protein_id="WP_042208665.1"
                     /transl_table=11
                     /translation="MREDVVDLLWEGLRQTLYMVAWSSVFALLLGTLLGITLVVTDKGG
                     ILAAPGVNKVISTAINGVRSIPFIILIVLLLPLSRLIVGTTLGPTAAIVSLSIGAAPFL
                     GRIIENALREVGDGKIEAAKSVGAGPFTIILQVLIPEALPALVRGMTIAVISITEFTAV
                     AGAIGAGGLGSLAIRFGYQRFRTDILLGTVLLIILIVQILQWFGDYIARSIDRRRFKNG
                     "
     gene            complement(23251..24060)
                     /locus_tag="PDUR_RS25210"
     CDS             complement(23251..24060)
                     /EC_number="7.4.2.11"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005831200.1"
                     /locus_tag="PDUR_RS25210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="WP_042208666.1"
                     /transl_table=11
                     /translation="MITVTNLNKSYRTRSGTVSALSDINLHIEKGEIFGIIGFSGAGKS
                     SLIRCLNRLEEPDSGSIQIGETVITDLKERELRLARRKIGMIFQQFNLFDSKTVFGNVA
                     FPLKAAGYKKPDIERRVGEILDLVELGGKAGSYPSELSGGQKQRVGIARALAGEPDVLL
                     SDEATSALDPQTTHSILELLADINRRLGLTVVLITHEMDVLRHICGNAAVIEAGRIVEN
                     APVRQLFHNPQSDTAKRFAGIFDFYNNTGNSGQLDVPAQAEREAVLR"
     gene            complement(24281..24502)
                     /locus_tag="PDUR_RS25215"
                     /old_locus_tag="PDUR_26225"
     CDS             complement(24281..24502)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PDUR_RS25215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PDUR_26225"
                     /product="hypothetical protein"
                     /protein_id="WP_042208667.1"
                     /transl_table=11
                     /translation="MSAYDDFAKEKQEIDDLLLQGYAVTGMLETLDGAKVKFDQGEPGS
                     ESVELLLLTADARKYVTTLVFAGLQKAQ"
     gene            complement(24502..25929)
                     /gene="hydA"
                     /locus_tag="PDUR_RS25220"
                     /old_locus_tag="PDUR_26230"
     CDS             complement(24502..25929)
                     /EC_number="3.5.2.2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hydA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019914879.1"
                     /locus_tag="PDUR_RS25220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26230"
                     /product="dihydropyrimidinase"
                     /protein_id="WP_042208668.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2e-20, bitscore:
                     71.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLIKNGTIVTAADTFTGDVAIENGIITEIGLNLKADGAEIIDA
                     SGCYVFPGGVDPHTHLDMPFGGTVTADDFETGTIAAAYGGTTTVIDFCLTSKGLPLQQA
                     VNTWHEKSQDKAVIDYSFHLMVSELNDKVLAELPQIIENEGITSLKVFMAYKNVLQADD
                     GTLFKTLQAAKQEGALVMVHAENGDVIDYLVSTALAEGNTDPIYHALTRPPELEGEATG
                     RAAYLTELTDSQLYVVHVTCAEAAWKIEEARKKGLRVYGETCPQYLVLDQTALEKPNFE
                     GAKYVWSPPLREQWNQDVLWKSLWNGSLQTIGSDQCSFNFKGQKELGLGDFSKIPNGGP
                     TIEDRFTILYSEGVEKGRISLNKFVDIIATSSAKLFGLFPQKGTIAIGSDADIVIFDPA
                     VKRTLSAETHHMNVDYNAFEGFEVKGEPVSVLSRGEFVIRNKQFVGKPGAGKYLHRKRF
                     GAAPVLPAKTEVSGGVV"
     gene            complement(25932..27221)
                     /gene="preA"
                     /locus_tag="PDUR_RS25225"
                     /old_locus_tag="PDUR_26235"
     CDS             complement(25932..27221)
                     /EC_number="1.3.1.1"
                     /GO_function="GO:0017113 - dihydropyrimidine dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /GO_process="GO:0006210 - thymine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006212 - uracil catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="preA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019914878.1"
                     /locus_tag="PDUR_RS25225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_26235"
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="WP_042208669.1"
                     /transl_table=11
                     /translation="MADLSINLAGIKSPNPFWLASAPPTNTGYQVQRAFEAGWGGAVWK
                     TLGDPIINTSARFAAVNFNGQRVAGFNNIELITDRPLDVNLKEIYETKKRFPNHAVVAS
                     LMVEPKQEKWHEIVKRVEDVGVDGLELNFGCPHGMAERGMGAASGQQPDLVEAQTYWVK
                     EVAKTPVIVKLTPNITDITVTARHAVKGGADAISLINTINSLAGVDIHTWNTIPHIGGK
                     GAHGGYCGPAVKPIALNMVAECARHPEVTVPISGIGGISTWQDVVEFMLMGSTAIQVCT
                     AAMHHGFRIVEEMIDGLNNYLDEKGLASVTELTGKSVSKYSNWGDLNLNYKVVARINEE
                     NCINCNKCHIACEDTSHQCIDMLTNAEGKAILKVREEDCVGCNLCSIVCPAEGAIDMVE
                     IDSGLPPMTWNERQSVVGNLSGSYSKAEVF"
ORIGIN
        1 tatttcatat agtaatgcga caaaataaat aagggcacca tggaaaccag aaacgtaatt
       61 gcataggcaa gattatatct aaaatgatga atcactttac taaacaggaa cgcggagaac
      121 gtatttagga aagtgaaatg aatgaggtaa agagaaaatg aaatttgtcc taaataagca
      181 aacggtttcc atccaaacac atgctgcagc acttttaaac gaagcagagc aaacaaaatc
      241 ataacagaac ctagggttcg tgcaagaagt cgtggttcga tgtcaaattg aatccattca
      301 ttgatatttt ttgtccacac ttctatgggt tcgtacatag tccccattaa tggagtataa
      361 ggcgccgaac ctaagtaaat ccccattaaa agcacaagta ctgccgttat tttactttgg
      421 acccatttgt gcttgagtaa atcggcgagc agcattcccc acaaaaaagc gacaaaatag
      481 gtttgaataa aagaaataga taagaccaca tacacaatcc atcttttttt cactcgtcca
      541 aataaagcaa gaagaccgaa aattaaaaaa gaacctaata gctcatagct cattgtccaa
      601 aggactggat tgtaaggatg tgctttaaaa cggaaaaacg gatcaaaaat agcagccttg
      661 ataacggtat atacattagt atctaaagcg tagtagttct ttttcatatc cgtccaagtt
      721 gttccccata tttcttggag atgaaaggca ttcgtaataa ttgctagata cacaagcaat
      781 acggataccg ctgccggcac ggcaagccga atgtaccttc gtagggcgct ggaatgcaac
      841 aatttttgaa aggtctcact atcgagctct ttttcaaaca ttttgacact gagcacataa
      901 ccacttagca caaaaaacaa acaaacggca aattgtccat tataaaataa attaattgga
      961 gaatgtccgt accagatatc ccattcaaaa tgagcttgtt gcggtcttcc atttaacgca
     1021 gctggataaa atacttgtat gtagtgcgaa ataaccacgg caaatgccgc gagtccccta
     1081 atgccatcca aatagaataa ctttttttcg gatgtctctt tattcatttt ttcctcttct
     1141 ttcataaata aaactatttt aacatgcaac gctgcgcgat taaacgcaca tcgagaacca
     1201 tttttttcct tttaattaat attcttattc gtcgttttcc ctcatttaca tggtgtagga
     1261 atcccttata tggactatgt cctcctctat atacctgtct tatcagttta tctaccatat
     1321 cgtgttggat ctcttgatta cggtaaaagt aatcatataa gtttgttacc agcgtaatta
     1381 tgagattcac tgatttttct gttctttcgc ttcaacctct tgtaatggag taacttttcc
     1441 actttcaaat ggattacgca accaacctac aaagtccgcc agatccttaa ctcctatttc
     1501 tttaaaagct atagtttgtc tatctattaa aacaaaaaat agaggatatt agctcatata
     1561 atgaactaac tatcctctat ttacgatact ctaattaacc cggcttaaca ctttattttc
     1621 tcagtctaca actttagaca tataccgcgc tgaaatccgc actctgccct tccggctgct
     1681 ccggccttta gtccccgggt tactccagca gcgtcacgga cacgccgact tcaagcgtgc
     1741 tgctgccccc gcggtacacg ccctgcagcg ggctgacatc ggcataatcg cgccctgttc
     1801 caacacgaat gtgattgtcc agcgcctcca cattgttggt cgggtcaagg ccgacccagc
     1861 cgatgccagg taccatcacc tcgacccagg catgagtagc cgcatcgccc ttaagggcgg
     1921 aatcttcgcc gacgtacaaa tacccgctta cataccgggc cgggatgcgg cacgcgcgca
     1981 ggatgccgat catgacatgg gccagatcct gacacacccc ttttttcagc tcaaaagcct
     2041 gccgggccag cgtatccacg cttgtcacct ctccgcaata ggtgaacgtt tcgtatacat
     2101 acctcatgac ccgtaaagcg tactgaacgg gattgtccat ctcgcccagc ccgcgcttca
     2161 cttctgacaa ctgctccggg tgcagaagag tatagtcggt ctcgttcaga taggacagat
     2221 aatgctgccg gaattgctga gaatgaaaaa tatcctgcat ccgtttcaaa taccggattt
     2281 catgaataaa ggaacctcgc tgaatgctca cgaccgacgt ggtcttcact tccagcagat
     2341 tatgcttctc gggtataaaa aaagtctcca cctgattgcc ccacaaatcg gtgtattctt
     2401 tggtcaggga agccggcgta atctccgccc ggtacattag caaccgctgt acttcgtccg
     2461 tcaaaggttt aagccggatc gtattcaggc tttgatcgac ctgcgtttca tacttgaacg
     2521 tattcgtatg cataatttca tagttcatcg aacctgcgtc tccttttggg cattctgttg
     2581 tacattaccc atagacgcgc ggcttgcaaa cgcccataga agactgtacg ccactatttt
     2641 cccctaactt tgaggaaata gccatggacg gatacggcag ccgaagtccg cgtgctgtgc
     2701 gggtcttttt gtttaaagta tcgtaaattt attagaagtc cttagtttta ggtactctaa
     2761 atgtacatgt ccatctgccc atagtctcaa tccatctgaa gacaaatcat ttaatactaa
     2821 attactcagc acgtattccc cgtcattgat aaatacttcg acggcacccc tgtctactaa
     2881 tatatccaac ttaattttcc cgtctttcgg ctttacgatc actctttgtg gtctcttgaa
     2941 ctcctcaaca tcaatcttta tccttgaatt ttccctatta aacacaaatt catttattga
     3001 tttatcatat gtcaaatctg catgctgccc atccccatct ctaacagaaa acccaaactt
     3061 tccttccgtt aaatctccga catctatttg ggcctcaatt gaataagaaa gtccatgaaa
     3121 atctttaaaa atattctctt gacccgtgta tatatcttcc tcttttatat ccaatattgt
     3181 gggaaaacta tccagaagat tccatactgg tttttgcacc agctttaatc cttctgttgt
     3241 tgtttttagc cgcatttctc ttacgatact cgtatttcca ttaaacgtat cccacgggag
     3301 cttgcgagcg taattccaat tattcatcca cgaaataaag tacctgtagt tcccatttgt
     3361 atacggagca tcccaagtaa cccctgtata ggagtctgcg ccccgttcca gccatttgac
     3421 aggagtttca gcgtgaaact cccttccatc aaagtcccct acaaagtaac tggaacctgt
     3481 ggtaacacca taattaaacc catttccccc taccatcaag acccattttt tagtgtcgct
     3541 attatcatct acgttcaatt gaaaaagatc aggacattca acaattccaa tatcctgtct
     3601 gacaaaagaa gaagcatact cccagtcttt taagttagaa gatgtataaa tccctacttt
     3661 atctctttct gctaatagca tgacccactt ttttgttggt tcatgccaaa tgattttggg
     3721 atctctaaaa tcggcacttc ctgttgggtt atgctggacg atattataat gtttaaagga
     3781 atttccgcca tctgtactat accaaaggtg agtagattgt ccttcaaatg gcatcgttac
     3841 taacgcaatt acagcattgt taccaaaccc tgctgtgtta ttttcatcga taaccgtact
     3901 gcccgtccaa gggtctccat acggagtttt atatttttct atagcgactg gttttctctc
     3961 ccagtgaact aaatccgtag acaccgcatg agcccactcc gtaccatttc caccccatga
     4021 aaagtcgtcg ttataaagat agtacagatg gtgttgaccg ttgatgtata aaggtctttg
     4081 gacgtcgttc atccactctg cttgaggagt aatgtgatac tccggacgat ttaattcact
     4141 atccgcaaag gcttctttcg atccaacaaa tccaaaagta aataataatc caacaaggac
     4201 tgcgtatagt acacctttta cttttttact tataaatttt acgctcattc tcattcaatc
     4261 cccttcctct tactgttttt cattccaact cttccctcat atatttgata tatcggaata
     4321 cgccagctca aatacaatat ctggatcgac aaatttcacc aaattcttgt atatttcttc
     4381 taatggagat atccatgggt gcgcgggatt agtcgaaaac tgggtttttg tgcggaaaat
     4441 ccggagtaaa acgtgtagtg gatatgaagt gaagctatgg atataccgga gcgaaaggaa
     4501 accgagggat cggggtgagc cagggggcca gagcggcttt cgctcgccca taatttgctg
     4561 aggaaacatg cggtaggcca aaatgaaacc ggccggccaa ggatgaattt gatatgctcc
     4621 ccatacagta gacaggtgaa ataataaaaa cttgttactg tgaggggagc atttttcatg
     4681 caaaaaccac catatcaagt tgcgcagaaa ctcatgatcc tacaagcaat ggaaagtggg
     4741 cagataagta tcagggcagc cgcgaagatc tatggcatcg ggagaacaac cttggcagag
     4801 tggcagccgc gatatgaggt gtatggctat gccgggctgg agactcggac ccgtaatcga
     4861 aggtattccg cagagttcaa gcttcaagcg gtactggatt atctttcggg gagtttgtcc
     4921 caatcccaaa ttatcgataa ataccaaatc gtcagccgaa cccaacttcg caattgggtg
     4981 aagacgtata atgatcatag cagcataaaa atctattcag gtggaacaaa ggctatgacc
     5041 aaggggcgga cgacaacgtg gcaggagcgg atagacatcg tgctctattg ccttgcacag
     5101 caacacgact atcagaagac agcggaccat tttcaggttt cgtaccagca ggtgtaccaa
     5161 tgggtcaaga agtacgagag gggtggcgag gatgcgctcc gggatggccg ggggggcgaa
     5221 aaaaggaacc cgaagagacc accgaaacgg aacaccacaa gctcgcaatg aagaagctgg
     5281 aatatgagaa tgagcggctt cgggccgaga atgcgttctt caaaaagttg caggaactcg
     5341 aaagcaggcc gacgctaagc gcacatcgtc aggaacggat ttatctggcc attcaggcgg
     5401 ttcatgagca agaagccttc ccggtccagc tgttatgtga tcttgcaggg atttcacgat
     5461 ccagctacta caaatggcgg gcgcatcgcc ccagtgcccg tgaacgggaa aaccggaagc
     5521 ttaccgatgc cctgatttcg ctgtacgagc aggttggggg aatctacgga taccgccgac
     5581 taaccctgca tctgcgccgg cagacggaac aagcgttgaa tcccaagcga atccgccgct
     5641 gatgaagatt cgaggcattc agtcggtgat ccgcagagcg cgaaaagcct atgcccgatc
     5701 caccccgcag caggtggcag agaatctgct gaaccgtaag ttccatgcgt cggctcccaa
     5761 taaaaaatag gtaaccgatg tcacggaact caaatatgga aatggcgaga aggcctattt
     5821 aagtgccatc ctggatcttt atgacaacac gattatctct tatgtactgg gggcgttcca
     5881 acaacaacgc gcttgtcttt gaaacggtac gaaccgcctt gcggacggca cagggaagta
     5941 agcctatgct tcatagcgat cggggttttc agtacacctc tttgaagttt aagaagcgat
     6001 ttggtgcaaa actgacgcag agcatgtccc gagtgggtcg atgtatcgat aacggtccca
     6061 tgaagtcctt ttggggaacc ctcaagtgtg agcggtatta cttgcattct tactcgacct
     6121 ttgaggaact tcagcacgat atggaggact atatccattt ttacaataac gaacggttgc
     6181 aagccaaatt aaacggcctt attcccatgg aattcaggac caaggccgcc taaacgcttt
     6241 tattttttat gctgtctact tgacggggag cagttcaggc cagtcttttc cttcactatt
     6301 attgttcaaa acgttcgaag attagctcca acgttgacac ctggcccccc gccagcactg
     6361 gcatcgggac aatgctgtgc aacttccatc cccttgctga atgctgctcg atcacctgcc
     6421 ggtaatcttc cttcaacttg ccactcagcg ttcctacgga aatggataca aattcatatt
     6481 tatacatgat tcattcctcc ttgtcagttc ttcagtttaa gagcctggtc cacaataacc
     6541 tcaccgtagc caaatttgtc atccctacct ggatcgccaa gatcgacagc actttgcttc
     6601 agaaggcgga aaatattatc ggcttgcgga taatgatgat gcctgtcgta atagttcgaa
     6661 atcagcagag ctgccgttgc tgatacttgc ggcgcagcca gactcgttcc gaaggaaagg
     6721 gagtagcctt gcggaatatt cagcataata tccaatgcag tgttcggtaa cgacttggga
     6781 aatgccgtca acatcagatc cgtcacgttc acatttccgg tcgtatcgaa gtcgtcgcca
     6841 aaatacccgc cgtaagcgac aaaatcaata tatgggccat agttggaata aggagccagc
     6901 cgattgctct tcattaccgc accgacactg atgacatgct ccagcatact gggggcatga
     6961 atttcatttg acgcagcatt ggatttatca ccggtcccac ggtttccagc agacgccaca
     7021 ataatggcat tcattttatc tgcataatcg accgcccgtt ggtaagcttc ccgcagaata
     7081 cgccctgcat catccaatcg gatataactg ccagcactga tattgatcac ctggttcccg
     7141 tcattggctg cccgaacgat ggcgcttaga agtgcgaagc tgttcccgcc accattattc
     7201 atgattttgt aagggacaat gctgatcttc ggagccagca gactcaaaac gcctgctacc
     7261 tgagtaccat ggccattctc atcctgaaca ctattgttgc cgtcaacata attccagctg
     7321 tccactgtaa gaattgtctg tccaaaatgc tcattcgcta aatccacacc actgtccagc
     7381 aaagctatct tgaccttagg attgccttcc tgaatatcat atgtcgtata atgattagtt
     7441 tgtgcttccg cataccataa atacgcattc agttcttcca ttccatgcaa atcccagtag
     7501 tttctgtttt gaagcatttt ggcttctgcg gattctccgg ggtccttata ccaggaaaaa
     7561 tccacctcgc ttgcggattt cttcagccac ctatccaatt cctcagaagt tccttgcaac
     7621 tttaggaagc caatttcctg aattttatct gccgtaagct gacttttact tagaagagaa
     7681 tcgatcgttt tcatttggtg cggtctgtcc agcagaacaa atatcgtctc cgactgactg
     7741 tttcccacat ccacagcgct gaccgttctg aaaggcgtgg ctgcaaggag cgcgcacacc
     7801 atgagcagca acagggacgc cagcggtttt ttctttttca aattacactt cccctttctt
     7861 caaacgggtg aatacgcatg ctcttgaaat ttagcgtaaa attccgcata gaactcactt
     7921 ttcttcagta ggtcatgatg cgttcccagg gccgtaattt ctccattctc cattacgatg
     7981 atgagatccg agtccataat ggtcgtgagc ttatgggcaa tcaccacccg ggtacatttt
     8041 agccgtctta aaaaatgatc aatgcgcttt tcattctgat gatccaggga actggttgct
     8101 tcatccagca gaatgacaga cggcttgttt agcagcgccc tggcgagagc gattcgctgt
     8161 ctttgtccac cggagatgtt cattcctagt tccgatacca tggtgttaaa tcccatcggc
     8221 attctgacaa tatcctcata gatttcagcc atctttgtga cgctttgaat ttcctccaga
     8281 ctgacatctt ccttatacaa agagatatta tctttaatgc ttcggttgaa cagagagaca
     8341 tcctgtggaa caacgccaat ttgcttacgc aaggcgctca gattcaattc gcggatatcc
     8401 ttgccgtcaa aataaacctt accattcgac ggcatataca ggcctagaat tagcttggcc
     8461 aaggtgcttt tgcctgcacc ggactgcccg acaattgcta ttttctggcc ggatacaata
     8521 tcaaggctaa tgtccttgac cacccaatcg ctgtgctcgc tgtatcggaa tgacacattg
     8581 tctaggcgga tgttgccttt gaactcagta atgctctcct tgtcatcgtc cgtatgctcc
     8641 aacggctcgt ccagtacatc ctggacccgc tcaagataag cgcctgtcaa cataaacgag
     8701 ttgatcgttt ggacgatgga accgctcata ctgaagaagt tattcgaaag cgagtagaac
     8761 gcgatcagtt cccccagcga aagctggttg ttaaatacca gcatggcccc gatccacagt
     8821 accagaagcg gcgacatcat ttggagtgtt ccggaaaggg aagcgatcat attcatgaac
     8881 ccttccttgt ttttgtaagc ctgaatcagt tgatcgagaa aggaggccca gcggtggtaa
     8941 gtttccttct ctatgcctgc cgttttaatt ccgaagatac cgtacaaaaa ctcggtttga
     9001 tagctctgaa gttgggaggt tttcagaatt tcgtcttgat ttacctcttt taacctgcgt
     9061 ttggtaagga tcagcatcag aacattcaac agcgacagcc cgaccaccag actagttaag
     9121 actaaggatt tattaagcat gtaaattgta ataaatgtaa tcgcactgaa atcaagcaat
     9181 ccaagtacaa gcttagaaga gagcatctct ctgataatcc ggaggctact cgccctgaat
     9241 aacagatccc caaacgacct taattgaaag aactggtaag ggagtttcaa gatatgagaa
     9301 aagaaatgct gcatcatcct tttatccaac gtattgttca gtacaatgat gaatttgcct
     9361 cggaaaaatt gaacaaaacc ttgaacgatc gtcaaaaaga taacgctcac cataaagatg
     9421 gacagtaatt gaaatttatt ggccgtaata atgttatcaa tgagatattg gaccaagatg
     9481 ggcatcccaa gtgttcctaa ctggtagata attgctatta taatgacaat agtcactttt
     9541 ttaggaattt ccataagata cttcagaaac ttgccccaaa ccgatactct tttttgcgga
     9601 acgacttgtt ccgtcggggt catttccaaa acaatgaaat tatagctttt ctgaaattcc
     9661 tcataggaaa tcgtttgtct gcccacagcc ggatcgataa tttttatgct gtttttgttt
     9721 attttatcga tgactacata atgattctcg ttccaatggg caatcaccgg cagccgaagc
     9781 tgcgacaact gatgcaattc cgcccggaat actttggcct tgaagcctaa ccggacggcc
     9841 gtatttcgca tcgtgtacag tgtgacaccg tcacggccta tgcccgccat gttccgcagt
     9901 tcccttaggg tcttgtgggc attgtatttc ccggcaacca tcgaaataca gcatatgcca
     9961 cactccgtct gctgcatttg ttccacaaac ggcgttctat ttatgaacat acatctacct
    10021 cattcagcgg gatatccagc gccagaatag atggaatctc agggtcaagg agccgcagca
    10081 taccaaaagc aattccgcta attccagtaa acagaccaag cgactcgata tcaggatgca
    10141 tcccggttct ccatggtctg tccggtgttt tgttaagctg catccactca gcttcaccgg
    10201 ccagcttcgc tccttgcaac aaacggtgta catccaggag aacattgcgg ttccccagtt
    10261 ctccatgaca catcgaatgc ccagtggctc cctccgtttc ggaaaggtcg ttcagcaaac
    10321 ggtcaatcat cagaagctcg gctgggaagc tgggcagcag agcatggata tgggctcgag
    10381 ccaacagaat accgtatgaa ccgtgacacc aataattagc ggctagcgca tgtttgttct
    10441 cccgcaagtc taaccatttc cgctccgatc ccacataaaa gcgattttct atctccacca
    10501 gtttcatgat cgtacgctga atatcgcttg acggaagcac acaatagaca tgggccaagg
    10561 aaaaggcaat cccactgatg ccatgggcaa atccggcgga ccgcccgctg tccgaatgaa
    10621 ttacagtatt tctaatttgc tgcaaatatc gttctgatag gatctgaagc acccgaatga
    10681 cttcatcggc cggatatgca cggtaaaggt tagccaatac ctttaataaa ccggcatggc
    10741 ccctgataat atctatctct tcttcgagcg ggagaagctt ttcaattgcg gggagcagac
    10801 caacggccct atgaagcaag gacgaatcat tccacaagca gcccaagtaa gaatacacgt
    10861 aaacaaacgc cccaatccca aaaaatgccg aggtcgagtc catattagcc aaccaaaact
    10921 tttcttcacc cataagcacg ttcaagatcg attttgcggt tctctcatat tccgccgact
    10981 ttaagaaaac acccagttga gcataaaaga tcgctattcc tccgatgccg tcatacacgc
    11041 ccggtgggag cggtgacagg aatatgtcgt cttcatttcc gacactggta ctgatccaaa
    11101 aggggcttct acccttctta tcatataagg ccttggctaa catcccgtca gcaattgtta
    11161 caatttcatc ccttagatga accggcgtgg gcagttctgc cggttgttct gaaatgccgt
    11221 tccagacgtt gtcgatcagc gtagccagcg acagcgagat ataccgctct tgcttcagac
    11281 gatctgcttc cgagaaggag cggatacgcg atttggtcaa tgccaggcta ctttctttat
    11341 agaagtccct gtattctttg cccgctgagt tatacagatg tttgccaccc acaaggaaag
    11401 tgaaataagg aatgtcatgg acgaccaaat cattgatttc ggaacggaca aacacattgg
    11461 cgagttcgga ccattccgta atggaccaca tataatcaaa caagccttcc cggtcaatcc
    11521 ccctttgcaa atactttgga tgggtgctcg cctctaggaa ttttccatac acatgtgtag
    11581 gtcggaagac atgccggact tcatccttgc tgaacatgtt caacagggac tcgaattcaa
    11641 atttatggga ttcgattgag cggtacgtgt cgcggaagcc ttccagcaaa tactctttat
    11701 agtcaaaaat ctgaatatcc tgtccgttga tagcaggaac attcagctta ttttttgtca
    11761 ccagctccgt ctcgacaaag gccatcgcat ccgtgccaaa gttgctgatg gtataacctt
    11821 tgttcctttt ggacttttgt cctcctctgc ccgcaatacc actcaaatcg tagtccaagg
    11881 cctgatcgtg attgaatttg accggcagca tcatcgaaga cagcacggaa ttcttcagct
    11941 ccagcgcagt gatatgaagc tggttctggt tttggaacaa atcaatttga ttatcgaaca
    12001 aagtctctaa atcgatcagg atcggatact cacccgctgc aatcaaattc tcattatgaa
    12061 aatcgacgga acggaaagca taaagaagag ccacattcat tccctgtctg taaaagaaac
    12121 gctggatctg cgcttcgtcg atacaatcgt catattgaat aaattcctgc cagccgtatt
    12181 gctcacggtc tagtactttg gcagcacgca aagaatgctt cacgccgctc gcattcaccc
    12241 aagccacgat ctcagtaaaa tgggagtcaa ccgcgagcga gcgcggtttg taaactagct
    12301 tgcccgcagt cgtctcaata atttccacac tgcgcccctt cttatgggaa tcgcccaaat
    12361 ctcctttgac cccggtcaag cggggtgagc ggaagccgaa tgtttcttca attgtttcgt
    12421 aatccatcag gaaatgcttt accagcgttt tatgtatttc aatcaattga acaagccgtt
    12481 cacagagaac tcttcccagt acagggtaca cctcaaaaat tcccgcgaaa ttctcggaat
    12541 cccccaagta ctgctcaaca aaataaatat agcgttcttc accgtcgctg cccttcagac
    12601 ttccttccat tcttgctata ttcagctcgg caatcagcat cttggtcgat agcttatcaa
    12661 tgtcgctatg gataatggaa ataacgcatt ccatgtattg atggatatca atcttagttt
    12721 tcaccagact attttctcgg gacagtgatt tgaagaaatc ttccatttca ttctggacat
    12781 aaagaataaa tggggtgaaa taagtaacaa aggatttatg ggggagctcg tattttatat
    12841 gcgagacagc ttttggatca taagctgtaa tttttcgtaa gacttgaacc cattccggca
    12901 aatgattctc tatcagttgc gggtaattcc ggattatatg ttcatagttt tgcttagtca
    12961 gacgaagcga actcagctta ttgtatagcg ctttctcgga aatattgtaa ttaaccgtac
    13021 cctcgtcgac attctccatc tcggttgaaa agggagccag ttcacgcagg taagcgctct
    13081 gcttaaacgc ggattgaagc ttattcatca tttatcatcc cttatcataa attaataaaa
    13141 aagggctacc atgaaaacaa acttcatgac agccgcttag caacggttca gctgcggctc
    13201 gtcctttgga ctccagagaa atcggctgcg gcacaagttt gatgcaacat aatacgcgag
    13261 cagatggggt tagtgttaac cctctgcccg caggtctctt catttttcct tctcccttat
    13321 tcttacaaaa aaaggatagc cacttaggtc aggtttacac tataacagaa gttaaattag
    13381 cattggctag tgcatttggt agttgggcaa aggcttgccg acaccgttac tcccgctgta
    13441 atacaagtcc atgaagatgt agtcagtata gtagtttccg gatttacatc gcctgctccc
    13501 ccagtgagca ttttcaattc ttcctctgta actacaccta cagttttact agttttcaga
    13561 aactcattac ggatcttcga atttttcata gaaatcatca tcctttcaaa attgtaattt
    13621 aaaatatatg taagaattag gggttgacta ccctttatgg aataaaatat actatgtctg
    13681 gaattccaag tctactaatt ttttcaatta aaggaaaagg agcgattact atgtacgaca
    13741 aagcattggt aacagcatgg aaaaacccga tggcgagaaa aggccttggt gctatccatc
    13801 atccttccgg tgatgtatta gcggaactga aagaagaaga cttgcaggat tttactggtg
    13861 gttttgacac caacactttg actacaagca caagcatctt gatcagcatg acactgggca
    13921 acaatggttg ggtttgtaca gccaccaaag aatgtatgcc tagctgcaac taaaaaagca
    13981 aggctacaaa ccgcgggcgg ggaccttatt tccctcgccc gctttaccta ttcgccttag
    14041 gaatgtatat tgctataact aattcactac aaatacctta gtaggtgtgt gccgaccatg
    14101 aacaataaat attatgtcta cagtgaaaga gaactcgtta cggatgcggc cagcaatgcg
    14161 gaggtacagg aaaaaacctc ttattggcgt actttgttta acgatgacca agattggctt
    14221 aacaaatcga tttccatctt tacaaatgac gatgtggaat caattgctaa atcctcttta
    14281 tctgcttcta tcgaattaaa taccagtagt tcatacgatc atgatcattg gctgaatata
    14341 aagtaccgtt tctttgccac ttacagcgaa tccggcttta cgacggataa cacaatacaa
    14401 aatccccttt tctttgatac ccttctgatg cgctttgcgt atgtggccga tttggagctt
    14461 gcttcccaca aggtagcttt acctgcttca attaaggaca aaaccttgta tcacctgaaa
    14521 aaaacacttc tggaaatcgg ctatcagacc cttattcttg aattgaacgt gttacgggtt
    14581 caagagcagt tgaccggtgg tagtccagaa gaaagatacc acagcttcaa ccgtcttttc
    14641 ctgaatgata tctcctatat ccattccttt tttgatgaat acccggttct gctccggctc
    14701 atgtgtacga aaaccgccta ttgggtacaa aatgttgccg aattactgca ccgcctatca
    14761 aatgatgctg aacaaattag ccagcagttc ggcgtcagcg gggatataat cgatctggat
    14821 ctcggccttg gcgactccca tgataaagga aaaatggtcg ctattatcac ctttgcgaac
    14881 ggaagagttg tctataaacc tcgaagccat gaggtggata tcaagttcca acagatcttg
    14941 agctgggtca acctcagaca gccgccgaga aaattggcca catatacgat tctgaattgc
    15001 ggaacctacg gctggtccaa ttttgtcgta taccgggaat gtgatcaact ggagcaattg
    15061 aacgattatt acatacggct gggtcaaata ctggccattt tgtacagtat tgatgccgta
    15121 gatttccatc atgagaacat cattgcctgc aaggatcatc cgattctgat tgacctggag
    15181 tctatattcc atcagtctaa acaaaatgaa gtttccatgg acaccgcaat ttctaaagcc
    15241 cgctacatac taacgcgttc ggttaactcg actggcattc ttccgttcaa ttcctattat
    15301 gaaaaaaaag acagcaaccg agtattggac ctaagcggtc ttagcggcaa ggaggctcag
    15361 gaagcgccgt tcaaggctta tcagatcaaa caatcttttc gtgatgacat gcacctggcc
    15421 aaagactcct tccagattca agaggcgcag aatgtaccga agcttaacgg cgagcctgtc
    15481 gaaattttgg aatatttgaa tttcattgtg gatggattca ggcaggtata ccaactcatt
    15541 caaacgaaca aagcatctta ccttgctctc ttgacgattt ttgagacatg tcctgtacgg
    15601 acgattattc ggccaacagc cgtctatgcc cagctactgc aacgaagcta ccatccagat
    15661 ttccttcggg atgccgttga ccgggaagta ttcttgtgca ggctggagaa attcattaat
    15721 gaagacacga actatgatgt cgcgagaagc gagttgctcg atcttttgaa tggagatatt
    15781 ccctatttcc tctcatcgcc cgccaccaca catttggaag cagcgaacca aacgtttgtc
    15841 gccgaatatt ttgagaaggc agccctgacc cgggttaggg aaaaaattga ttccttatcg
    15901 gacactgatc tgggcgaaca gctacatgtc attcggatgt ctatattggc ctcctttaac
    15961 gctaagcatc acaaggacac gctgatctta agtaaagaga ctgggaatat ttcgcttgaa
    16021 gcggtaaccg tcaccgatat tctgaactgc tccaaacggg tgggcgaata cgtattggat
    16081 cagcgcatta ccgccgaagg tagtgaagat ataagctgga ttagcacgat gattaaaggc
    16141 atcgatgaag tatcctggac tatatcgcct gttaacctag acttttacaa cggagtggcc
    16201 ggaatcggtt tttatcttag ttatttaggg aaaattttcc ctgaacataa cgttttccag
    16261 gaagtaacca tacggtgtgt caatacagtt atagattcgt taaacgagct gcaaaagcag
    16321 gatatggact ggactcctta tatggaagta ggcggattta cgggaatttc aagctacctc
    16381 tatttccttc agcatgcctc ggtcaatctg catcgtcccg aatggttcca agccgtgctg
    16441 caatttctac cgctgcttga agagctgatc gaaaaggacg aacaattcga tgtcaccagc
    16501 ggatcggcgg gagcattaat ggtgttctta tccctatatg agcagcagca agagaaggaa
    16561 ctacttgtgc tggccgagag atgtgtgcag catttgcagc gcaacgccac ggccatgtcc
    16621 accggtatcg cctggcgcga tccgtatcac cagaagttct ataccggctt tgcacatggc
    16681 tcatcaggta ttctagcggc actcgctaag ttcaataaag tgatggatgc cggttctatc
    16741 aaacgcacga ttcatgaggg cctgttattt gagagaagta tgtacgtttc caaggagaag
    16801 aactggaaat ccattggaag ggatcagctt tccgttgcct ggtgccacgg cgctcccggt
    16861 atactgctct cccgtcatat cttgcaggaa agcggctatc acgacaatga tctagaatct
    16921 gagattgatg ccggacttga gaccacaatc aagctgggtc tggacaataa ccgttccttc
    16981 tgccacggag acttcgggca gctcgaaatt ctaagcaatt tttccagcca atcctccgat
    17041 atacaggccg ttacatccga cctgtccgga cggctattcg aatactacaa caagcatgac
    17101 atgaccggag gcgtatcccg cggagtggag gcggtcggct tgatgctcgg atggagcggc
    17161 gtgggctttg ggttgcttca gcaagccctg cccggtaacc tgccgcaaat tcttcatctg
    17221 tccccgccag tcagatctta atgtccttgt gtataagtga agcttaacgc gaagcgccca
    17281 tcagccttat gatgcccgct tcgcgttttt caccgtaaat ctaccggtct taagtcgtaa
    17341 tatcccttct ggtaaaggtc acataggaaa tgctcagaaa ggctacaaag tagacagcca
    17401 tcatcgttag cgaaaaggaa agggtcatac tctcaactac cggcctgccg tccaaataag
    17461 cggataggtc gtaattcgca aaaatcaggt acttgatcca gccaaatttc atggcaaaaa
    17521 attgcgtcat cgttgttccg gtgaaataca acagcaagga gacacctacc gcaagtatcg
    17581 cgtttctaaa taataccgat acggcaaagg ccagagtagc caccatgaca atattggcaa
    17641 gggtcgctaa atatttcagg cataggtagg tcatcatcga catcttcacg atcgccccat
    17701 tttgataggc caaataataa ttgcttccgc ctgtacccaa ccacacatag cccaacaatg
    17761 aagccagcat cataaatgcc atgaacagta gcagaatatt tattacaact gaggcatatt
    17821 tcagtagcag ataagtccct ctacgtatcg gcgaagtaat gacaaatttg atggttccct
    17881 tagcgtgctc ggccgctatc gcattggcgg caagaacaat cgctaccagc gtaatcaacg
    17941 tagtcaccgg tcttaattca ttaatcagtg tcaatgcgtc atatttagaa gtaggcggaa
    18001 gatcatggtc aagccggtac tggttcacga caagctgttc ggacagaaat cggtgcatgg
    18061 gcatggacgg cgacaaggct gccatctgtt tcttatcctc ttgaatctga ttctcaacgc
    18121 cggatctcca gttcccgctg tccgcgagag tgttcggcct gctaaagcta accaagagag
    18181 tataagccac ggtgatgaaa aacagtagca atgtaataag ccatgtgttg cgatttttat
    18241 agaaccggta cagttcatta cccaatagtc gcattagctt gcccccttat ttgcgttcag
    18301 taatgctatg aaatcttctt ccagtgtcca tctggcctgc ttcatattca atacttcgat
    18361 ctgatgatga ttcagcatgt tgatcacgat cattattttc tcttcaggca gtacaaaact
    18421 taattcatac gccgcttcat tacgcttcac ctgatatcca gcctctgtga gcagctgcat
    18481 tgctcgcttt atgcacgtgg aatcaaacga aagagtatac cgaaattcat ttgccgctct
    18541 tccattctct ttaatttcca acagttctcc atcgttcatc acgccgtaat aatcgcataa
    18601 taactctacc tcggaaagca aatgacttga gaggaaaacc gtcttctcgt gcttttcggc
    18661 aagtccccgt aggattcgtc ttaaatcaat gattccctga gggtccatgc cattggttgg
    18721 ttcatccaaa ataaccaggt cgggattatg cagcagcgaa acggcgagac cgagacgctg
    18781 cttcattcca agcgaatatt tcttgactct cttgttcgcg ctatcgctta gtccaaaagc
    18841 ttcaagctgg cgttcaatat tcaccttgtt tggtttcata tgaaaggccg agatataacg
    18901 caaattctga aaccctgtca tctccccata aaaagagggg ttctcaatca ctgcgcctac
    18961 cttccggatt gcatccttga attcggattg aatggagctg ccaccgatac gaatatcgcc
    19021 tgaagacatc ttcattatgc ccaccatcat cttgatcaag gttgttttcc cagccccgtt
    19081 cggcccaagt agtccgaata ttttcccttt gggaaccgat aaactaacat tcttgataat
    19141 attcttgcca ccgattcttt tagagacttg gtttattgat aaaaagtcca atttgattcc
    19201 tcccaaccgc gaacaaccgt ccgctcctgt caattaattg cgtttccaca gaccgatcca
    19261 aatgaagaag ccaatcacaa aagacaacga aaataacagt gtgaccatat ttctgtacaa
    19321 ttcgtaaccc atgtccaccc aagaactaat cagaatgaca agcgagaagc ttgcactcag
    19381 gagaaaaaac atatacttaa aaaacttgtt gaaaatataa agaccgcgct catccctgac
    19441 tccggcaatg ctgagaatca taatactaac gaatgccagg aatcccaata ccgcaaagat
    19501 cgaattcatc aatgtgagag agttcatata ctttcctacc tttcataatc gaacacctca
    19561 tatatactct tttggaaaac ctccgcgatg cgaaaagcca gtttcaaaga cggcatatac
    19621 ttgttccttt cgatggagat caccgtctga cggctgactt gcaaggcatc cgccagttgc
    19681 tgttgagtcc agcccctctc cgttcgcagt tcaagaatgt ggtgtttaag atacgaatca
    19741 ccgtctccca tatttaccat tccttaaaaa aataatgttt ttttgtatca tactaccaat
    19801 tttatcaaat gtaaagatga ctttacattt cttccattag tgtaattgct gaaaacaaaa
    19861 aagaagaggc tgtcccaaaa gtcatcctaa atgacttttg ggatcgccct tgtttccatt
    19921 ttgtaaaaca aaaagaagcc gttccttagt aaaatggaag tgtcgagtaa ccattccaaa
    19981 ggagggcttc ttttgtacat tcacgatagc atggatcaac ttcatctgcc aatggacctg
    20041 gaggaggact ttcctccaaa ccacttcgtt cgtgtcgtaa acgacatggt gaaccgcacc
    20101 tgcgataaga tctttgcggc tgctcatccg ggcgccggaa ggcacagcta ccaccccaaa
    20161 atgctcacca aaatcatcct ctacgcctac atcagcggat ctactcttcc cgtcaaatca
    20221 ccaaggctgt gcgggaaacc atcccgttca tgtggctggc cggatgccag cacccggact
    20281 tccgcaccat taaccggttc cgcagcaagc ggatgaaaga cgtgctggag tccctgttta
    20341 ccgccctgct ggaactcata atccaaggcg gctacgtcaa agtggattac tattttgtgg
    20401 acggcaccaa gatcgaggcg aatgcgaatc ggtatacgtt tgtctggcgc aaagtggtgg
    20461 ttcggtacaa aatgaagctg caggaaaagg tgcgggtact gttccagacg attgaagagc
    20521 aggaacagca agaaaatcta gcccatgaag gtgcagattt ggcggagctt gggggaatcc
    20581 gcttcactaa gcaacgaagc gtcggaacag gccctaggat aagccgctaa agaaagcagt
    20641 ccgcttgctg aagcgggatt acctgccgcg catgtagcgc tacgagcggc aagagcgaaa
    20701 cagctacagc aaaaccgacc cggacgccac gtttatgcgg atgaaggaag accacatgaa
    20761 gaacggtcag ttgaagccag gatacaatgt acaggcggga acggaaagcc agttcattgt
    20821 gggctacagc gtgcaccagc gaccgaccga tacccgctgc ctgattccac acttgaagca
    20881 actgcagaag aggctgggcc aactgccgaa aaccgtcgtt gctgatgcgg gctacggcgg
    20941 agaggagaat tacgcctatc tcgaagagga aaattgcgaa gcgctggtaa atacaatacg
    21001 ttccaccggg aaacgaacaa gtcctggaaa accgatcccg ggaagttgga gaactggaca
    21061 tatgaagaat agaacgacca gtggatttgc cgaaatgggc gaaagctgga ttttgtgcgg
    21121 gaaagccgga gcaagttaga cagcggttat gaagtgaagc tgcgagtata ccggagtgaa
    21181 aactgtgaag gttgtcccta aagagtggct gtacctaggc gaaaggcaac caggaaattc
    21241 gagtgagcat ggcgtacctg cggtacaagg agcaggcgcg ggagaagctg cggagtgagg
    21301 aaggccgggc tctttccgcc cggcgaatgg cggaagtgga aagagtattt gggtaaatga
    21361 agaacaaccg gggattccgg cggttccttc ttcgagggct tgcgaaagta agcctggagg
    21421 tcaggcggct ttcgcaagcc cataatttgc tgaggaaaca tgcggtagac caaaatgaaa
    21481 ccggccggcc aaggatgaac cccttgaccg gccggtttgc tgttttttta tgtgaggagc
    21541 cgtaaagttt gtagacacct gcttttagga cagcctcaaa aatggattgt actaaagttt
    21601 cattggcgat atctagaagg ccggaacgac agcaacgcca tatttatcct cgataaattt
    21661 tttgacatcc ggactggtca gcgccgcatc cagcttcttg atttcctcgc ggttctcgtc
    21721 ccctttgcgt accactacta cattggcgta aggcgaattc gcatcttcgc ggaacagcgc
    21781 ggtcttggga tcgattttcg catcaaggac gaggttggta ttaataattg ctccgtccag
    21841 atcaggcagc gaacgcggca gtgtggcggc atccgcttcg acgaactcca gattatgcgg
    21901 gttatccacg atatctttgg gggtcgcctc gtaagttgtc agaccatcct tcagcttgat
    21961 cagcccctgc tgctgaagca gcacaagcgc ccggtattcg ttggagggat tgttcggaat
    22021 gccgattttc gcgccgtgcg ggatttcgtc cttgctcttc agcttctcgg agtagaagcc
    22081 gatcggttcg acatgcactt tagccgtaac tacgaaatca tagcccttct cccctttgac
    22141 ggaatccaga taagggacgt gctggaagta gttcgcgtcg atctgcttct cctgcagcgc
    22201 aggattgagc tgtccgtcat catccagcgt aacaacttcc agattaactc cttcttcctt
    22261 cagcttcggt ttgatgaatt ccaaaatctc ggcatgcggc acagccgacg ccccgacctt
    22321 gattgtcact tccttgggcg cttcgcttgc agccgcgctg gtctgcggag ccgccgcctc
    22381 cccgtttccg ttctgcgatc cgcagccagc caagattcct gtcgccacaa tgaccgccgc
    22441 aaaccataag cttctttttc tcgccatccc aatccctgct ttctctgaaa aatgtatgta
    22501 aaaagaatgt acaaccggtg tatcatcaaa gctctaagcg cctcgtctaa acgcggaacc
    22561 ttagtcccgg cggcgtgtag tcgctctacc cgttcttaaa gcgccgccgg tcaatggaac
    22621 gggcgatata gtcgccgaac cattgcagaa tctggacgat cagaatgatc agaaggaccg
    22681 ttccaagcaa aatatcggtg cgaaaccgct gatatccgaa gcggatagcc aggctcccca
    22741 gtcctcccgc tccgatggct cctgctaccg ccgtgaattc ggtgatggag ataacggcaa
    22801 tcgtcattcc ccggaccaga gcgggcaagg cctcaggtat aagcacctgc aggattatgg
    22861 tgaacggccc agcgcctacc gatttggctg cttcgatctt gccgtctccc acttcacgaa
    22921 gggcattctc gatgattcgc ccgagaaacg gagccgcgcc gatagataaa gagacgatcg
    22981 ccgccgtcgg accgagcgta gtacctacaa tcagccggga taaaggcagc agcagcacaa
    23041 tcaggataat gaacggaatg gaacgtactc cgttaattgc ggtgctgatc accttgttca
    23101 ctccgggagc ggcaagaatc cctcccttat ccgtaactac cagtgtaatc ccgagcagcg
    23161 tgcccaggag cagcgcaaag actgacgacc atgccaccat gtacagcgtc tgccgcaacc
    23221 cttcccacag caaatcgact acatcttctc tcatcgcagc acggcctctc tttccgcctg
    23281 cgccggaaca tcgagctgtc cgctattccc ggtattgttg tagaagtcga aaattccggc
    23341 gaaccgcttg gccgtatcgc tttgcgggtt atggaacagc tgccggaccg gagcgttctc
    23401 aacgatgcgg cccgcctcaa tcacggcggc attgccgcaa atatggcgca gaacatccat
    23461 ctcatgcgtg atcagcacaa ccgtaaggcc caacctgcgg ttaatatccg ccagcagctc
    23521 caggatggaa tgggtcgtct gtggatcaag cgccgatgtc gcttcatctg acagcagcac
    23581 atccggttca ccggcgagcg cccttgctat gcctaccctc tgcttctgtc cgccgctcag
    23641 ctcggaagga tagcttcctg ccttgccgcc gagctcgacc aggtcgagaa tttcgcccac
    23701 ccgccgctcg atgtcgggct tcttgtaacc cgcggccttt agcggaaaag cgacgtttcc
    23761 aaagaccgtt ttggaatcaa acagattaaa ctgttgaaaa atcatcccga ttttacggcg
    23821 ggccagccgc agttcgcgct ccttcagatc ggtaatgacc gtctcgccaa tttgaatact
    23881 gcccgaatcc ggctcctcga gccggttcag acagcggatg agcgaagatt tgccggcgcc
    23941 gctgaagccg ataatgccga atatttcgcc cttttcgata tgcagattaa tatccgaaag
    24001 cgccgaaacc gtcccgctgc gcgtccggta gctcttgttc agattcgtga cggtgatcat
    24061 gcttgaaccg accttctttc caaggaataa aaaaaatcaa gccctaatac gcctaacggc
    24121 gtttccggct tgatttccag tgatctggtc aatcaataat tcctattaat tcaatgcgat
    24181 taattgttaa ttaataatat agaataatcg ttaagtgatg tcaatctaaa aaagcgtacg
    24241 ccgagctccc ggcgtacgct tccttaattt ggcgaaacgg ctactgcgcc ttctgcaaac
    24301 ctgcaaaaac aagcgtcgtt acatatttcc gggcgtccgc cgtcagaaga agcagctcta
    24361 cgctctcgct ccccggctcc ccttggtcaa atttcacttt ggctccatcc agggtttcca
    24421 gcatgccggt aacggcatag ccctgaagca gcaaatcgtc gatctcctgc ttctctttgg
    24481 caaaatcatc gtatgcggac attaaaccac acctccgcta acctcggttt tggccggaag
    24541 taccggagcg gctccgaacc gtttacggtg cagatacttg ccggcgcccg gcttgccaac
    24601 gaactgcttg ttgcggatca cgaactcgcc gcggctgagg acggataccg gttccccctt
    24661 gacctcgaag ccctcaaacg cgttgtaatc gacattcata tgatgggttt cggcggaaag
    24721 agtccgcttc acggcagggt cgaaaatgac aatgtcggca tcgcttccta tcgcaatcgt
    24781 ccctttttgc gggaacaatc caaacagctt ggcgctggag gtggcgatta tatccacgaa
    24841 tttattcagc gagatgcggc ctttttccac accctcggag tacaaaatcg taaaccggtc
    24901 ttcgatcgtc ggtccgccgt tcggtatttt cgagaaatcg ccaaggccca gctccttctg
    24961 gcccttgaag ttaaaggagc actggtcgga gccgatggtc tgcagactgc cgttccacaa
    25021 ggatttccac agcacatcct ggttccactg ctcgcgcagc ggcggggacc atacgtattt
    25081 ggctccttca aagttcggct tctcaagtgc cgtctggtca agcacaagat actgcgggca
    25141 ggtctcgcca tagacgcgca gccccttctt gcgggcctcc tcgatcttcc acgccgcttc
    25201 ggcgcaggtc acatgcacca catacagctg cgaatcggtc agctcggtca gataggcggc
    25261 ccggcccgtg gcctcgcctt caagctccgg aggccgggtc agcgcatgat agatcggatc
    25321 ggtattgccc tcggccagcg ctgtgctcac gagatagtcg atgacatcgc cgttctcggc
    25381 gtggaccata acgagtgcgc cttcttgttt ggcggcctgg agcgtcttga agagtgtgcc
    25441 gtcgtcggcc tggagcacat ttttgtaagc catgaacact ttaagggagg tgatcccttc
    25501 gttctcaata atttgcggca gctcggcaag caccttgtcg ttcagttcgg acaccataag
    25561 gtggaagctg tagtcgatga cggctttgtc ctgcgatttc tcatgccagg tgttcaccgc
    25621 ctgctggaga ggcagcccct tgctcgtcag gcagaagtcg atcactgtcg tcgttccgcc
    25681 ataggcggcg gcaatggtgc ccgtctcgaa gtcgtcggcg gttacggttc cgccaaacgg
    25741 catatccaga tgcgtatgcg ggtcgacgcc tcccgggaag acatagcagc cggaagcgtc
    25801 gatgatctcg gcgccgtccg ccttcaggtt aaggccgatt tccgtgataa ttccgttctc
    25861 gatggcgaca tctccggtaa acgtgtccgc cgccgttaca atcgtgccgt tcttgatgag
    25921 cttcttcatt ctcaaaacac ctccgctttg gaataagaac cgcttagatt gccgacgacg
    25981 ctctggcgct cattccaggt catcggcgga aggccgctgt cgatttccac catgtcaata
    26041 gccccttccg ccgggcagac gatcgagcac agattgcagc cgacgcagtc ttcctcgcgc
    26101 accttaagaa ttgctttacc ttctgcatta gtcagcatat cgatacattg atgtgaagtg
    26161 tcctcgcagg caatatggca tttgttgcag ttgatgcagt tctcctcgtt gatccgggcc
    26221 accactttgt agttgaggtt gaggtcgccc cagttcgagt atttggacac cgatttgccg
    26281 gtcagttcgg tcacggatgc gagacccttc tcatctaaat agttattcag accgtcaatc
    26341 atttcctcca cgatccggaa gccgtgatgc atagccgccg tacacacctg aatagcggtg
    26401 gagcccatca gcataaattc gacgacgtcc tgccaggtgg aaattcctcc gatgccggag
    26461 atcggaacgg tcacctccgg gtggcgggcg cattcggcaa ccatgttgag cgcaatgggt
    26521 ttgacagccg ggccgcagta gccgccgtgg gcgcccttgc cgccgatatg gggaatggtg
    26581 ttccaggtat gaatgtccac tcccgcgaga ctgttgatcg tattgatcag gctgatcgcg
    26641 tcggcgcctc ccttgacggc atgacgggct gtaaccgtga tgtcggtaat gttgggagtc
    26701 agcttaacga taacaggcgt ctttgctact tcttttaccc aatacgtctg cgcttctacc
    26761 agatcgggct gctgcccgga tgcggcgccc atgccgcgct ccgccattcc gtgcggacag
    26821 ccgaagttca gctccagacc atctacgccg acatcctcga ctcttttgac gatttcatgc
    26881 cacttctcct gtttaggttc caccatcagg gaggcgacca cggcgtgatt cgggaagcgc
    26941 ttcttggtct cgtaaatttc cttcaggttg acatcaagcg gacggtccgt aatcagctcg
    27001 atattgttga agcctgccac gcgctggccg ttgaaattga cggcggcaaa gcgcgcggac
    27061 gtgttgatga tcggatcgcc gagcgtcttc catacggcgc cgccccatcc cgcttcaaaa
    27121 gcgcgctgca cttgatagcc tgtattggtt ggcggcgcgg aggccagcca gaacggattg
    27181 ggcgacttga ttcctgcgag attaatgctc aaatctgcca ttgataattc cctccctgaa
    27241 a
//
