LOCUS       NZ_CP009288            21923 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Paenibacillus durus strain DSM 1735 chromosome, complete genome.
ACCESSION   NZ_CP009288
VERSION     NZ_CP009288.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus durus (Paenibacillus azotofixans)
  ORGANISM  Paenibacillus durus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1  (bases 1 to 6038347)
  AUTHORS   den Bakker,H.C., Tsai,Y.-C., Martin,N., Korlach,J. and Wiedmann,M.
  TITLE     Comparative genomics of the Paenibacillus odorifer group
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6038347)
  AUTHORS   den Bakker,H.C., Tsai,Y.-C., Martin,N., Korlach,J. and Wiedmann,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2014) Food Science, Cornell University, Stocking
            Hall, Ithaca, NY 14853, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method :: HGAP, Quiver (SMRT analysis) v. 2.2
            Coverage                          :: 98x
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000756615.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:15:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,487
            CDSs (total)                      :: 5,373
            Genes (coding)                    :: 5,301
            CDSs (with protein)               :: 5,301
            Genes (RNA)                       :: 114
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 26 of 72
            Pseudo Genes (incomplete)         :: 54 of 72
            Pseudo Genes (internal stop)      :: 8 of 72
            Pseudo Genes (multiple problems)  :: 15 of 72
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:59:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2117764
            Orig. end                         :: 2139687
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP009288.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21923
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21923
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21923
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11923](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11923)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            365..3022
                     /gene="polA"
                     /locus_tag="PDUR_RS09495"
                     /old_locus_tag="PDUR_09910"
     CDS             365..3022
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="polA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019912006.1"
                     /locus_tag="PDUR_RS09495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09910"
                     /product="DNA polymerase I"
                     /protein_id="WP_042206064.1"
                     /transl_table=11
                     /translation="MDKLILIDGNNVIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLI
                     EEHKPTHLIVAFDAGKVTFRHEGYQEYKGGRQKTPPELSEQFPLLKGLLSDLGVPQFEI
                     ENYEADDIIGSISRQADEAGRQVMIVSGDKDMLQLASEHTTIALIRKGVTDIELYGPKQ
                     IRDKYDLTPQQIIDLKGLMGDASDNIPGVPGVGEKTALKLLAQFGSVEGVIAGTGELKG
                     KMKEKLEAHADDAIMSKKLATIYREVPLTHSWEDLAFHGLKKDTAGPALAKLEFKSLLE
                     RLSLSGSAPVNEESSSKAVQLDIVIAGEPELEELTAALTDVKALHVETNGENPHRAEVI
                     GLALSLLERHYFVPFELLKSGAAAGLRDWLADEHAPKNGYDLHRADLALHWQGIPFAGA
                     AHDVQLAAYLLDPTEANQNLSDLVAKYGLPRLAPDEEVFGKGAKYKVPELDILGAHVAS
                     KSASVLGLVPKQEQDLTETAMSGLFHDLEMPLSRILADMEKQGIAVNMDGLKELGREFE
                     STISGLVEQIYEIAGTEFNLNSTKQLGEILFDKLGLPVIKKTKTGYSTDAEVLEKLEPY
                     HEIVQKILQYRTLAKLQSTYVEGLLKEIAPSTGKVHTFYRQTIAATGRLSSQFPNLQNI
                     PIRLEEGRKIRKVFVPSEPGWSILAADYSQIELRVLAHISDDARLKEAFLHDMDIHTKT
                     AMDVFGVPAEAVDGNMRRSAKAVNFGIVYGISDYGLSQNLNITRKEAGRFIEQYFEVFQ
                     GVRRYMDEIVREARKAGYVTTLLERRRYLPEINASNFNLRSFAERTAMNTPIQGTAADI
                     IKLAMIHMDRALFERKLKSRMLLQVHDELVFEVPEDELETMKKLVPEVMEGALKLSVPL
                     KAEVSYGSNWYEAK"
     gene            3076..3912
                     /gene="mutM"
                     /locus_tag="PDUR_RS09500"
                     /old_locus_tag="PDUR_09915"
     CDS             3076..3912
                     /EC_number="3.2.2.23"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="mutM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689476.1"
                     /locus_tag="PDUR_RS09500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09915"
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="WP_042206065.1"
                     /transl_table=11
                     /translation="MPELPEVETVKRTLNTLVQGKKIQKVTVRLPRIIRRPDDIRVFET
                     MLEGHTIERVERRGKFLRFLLDGLVLVSHLRMEGRYGLYAAEEPLDKHTHVIFHFEDGT
                     ELRYTDVRQFGTMDLFLPGDDLSLPPLNKLGLEPLDPEFTPEAFKDLVAGKNTKIKPLL
                     LNQAYVVGIGNIYVDESLHRAGIHPETAAKSLTAEQLNRLHQAIVATLTEAVNAGGSSV
                     KSYVNGQGVSGSYQHKLLIYGRKDQACYSCGSVVEKSVVGGRGTHFCPSCQPLLLM"
     gene            4136..4861
                     /locus_tag="PDUR_RS09505"
                     /old_locus_tag="PDUR_09920"
     CDS             4136..4861
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689475.1"
                     /locus_tag="PDUR_RS09505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09920"
                     /product="MntP/YtaF family protein"
                     /protein_id="WP_052410143.1"
                     /transl_table=11
                     /translation="MISPIFSLLLLAFALSLDGFGVGITYGLRKLKIPLPSVLIISLCS
                     GVVMCVSMQVGVLLSKVVSPHIASLIGAVIILIMGCWSLVQLVVQRDDERTEGETGGMP
                     GNAENQSPDGLAVTDKTREEDPEKSAVFSLELRRLGIVVQILRTPSSADMDKSGSISPV
                     EALVLGVALSLDAFGTGLGAALLGFNPLWTSLVIALFSGSILLLGLHTGLRFAGTSWMK
                     HASVLPALLLIAIGILKLL"
     gene            4871..5470
                     /gene="coaE"
                     /locus_tag="PDUR_RS09510"
                     /old_locus_tag="PDUR_09925"
     CDS             4871..5470
                     /EC_number="2.7.1.24"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019534595.1"
                     /locus_tag="PDUR_RS09510"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis.; Dephospho-CoA kinase (CoaE)
                     performs the final step in coenzyme A biosynthesis; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="PDUR_09925"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_042206067.1"
                     /transl_table=11
                     /translation="MIMGLTGGIASGKSTVSALLIKKGARLIDADAIAREIMLPGHEVL
                     AAVTEYFGEGILLPDGTLNRTKLGDIVFHDPEALKALNGLTHPVIRRETRERMQAMERE
                     TPERLIIVDIPLLFESGLDDMFERILVVYAPREVQLERLKRRNGLTQDQAEARLNSQMD
                     IELKRSKADYIIDNSGDLADTERQIAVLWDRLGLPC"
     gene            5464..6033
                     /locus_tag="PDUR_RS09515"
                     /old_locus_tag="PDUR_09930"
     CDS             5464..6033
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009594633.1"
                     /locus_tag="PDUR_RS09515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09930"
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_407944293.1"
                     /transl_table=11
                     /translation="MLKWLLKKRVLLLLFLGFTAILFLSTNWMSWFYPIYFKEEIRKHS
                     STYQVDPYLVAAIIRVETNFKTGRESKKGALGLMQLMPDTAKWALEQAKLPDVSMSRLK
                     NEPSANIELGAWYLHSLSGQFDGNRTAVIAAYNAGPGTVQRWLADGSWNGSQEDIKNIP
                     FGETRHYVQRVIYYYNQYTEIYGGVF"
     gene            complement(6122..6352)
                     /locus_tag="PDUR_RS09520"
                     /old_locus_tag="PDUR_09935"
     CDS             complement(6122..6352)
                     /GO_function="GO:0003690 - double-stranded DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280723.1"
                     /locus_tag="PDUR_RS09520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09935"
                     /product="alpha/beta-type small acid-soluble spore protein"
                     /protein_id="WP_025334221.1"
                     /transl_table=11
                     /translation="MAQASNGQSSTNNLVVPRANAALEQLKYEVAQELGITLSPDGYQG
                     NKTSYENGSIGGYITKRLVTLAEQQLAGQFQ"
     gene            6479..6955
                     /gene="nrdR"
                     /locus_tag="PDUR_RS09525"
                     /old_locus_tag="PDUR_09940"
     CDS             6479..6955
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019912000.1"
                     /locus_tag="PDUR_RS09525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09940"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_042206068.1"
                     /transl_table=11
                     /translation="MKCPYCDHTNTKVLDSRPANENKSIRRRRECERCSRRFTTFEMVE
                     ETPLIVIKKDGSREEFSRDKILRGLIRACEKRPVSVERLEMIVSEVEKSLRGIAVAEVE
                     SQQIGELVMEQLYPVDEVAYVRFASVYRQFKDINMFMKELKALLSKNPAETEGL"
     tRNA            7150..7222
                     /anticodon=(pos:2124947..2124949,aa:Ala,seq:ggc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="PDUR_RS09530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="PDUR_09945"
                     /product="tRNA-Ala"
     gene            7150..7222
                     /locus_tag="PDUR_RS09530"
                     /old_locus_tag="PDUR_09945"
     gene            complement(7946..8374)
                     /locus_tag="PDUR_RS09535"
     CDS             complement(7946..8374)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PDUR_RS09535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_052410144.1"
                     /transl_table=11
                     /translation="MKKTIGLLLTLTIVLLTLFLAGCGNSTSSPSKDSEEPKFVNGKLT
                     KEFELKTPTFTGFNEFIIADLKGFFKEVNIKPVYTGVLAQGSNLAQSVIKGDNDLFGSG
                     HPTNIAVARKAGAKIKIVLHSMVDSPENNKLHMTWLDG"
     misc_feature    complement(8392..8401)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    8521..8535
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.75"
                     /tool="antismash"
     gene            complement(8785..9576)
                     /locus_tag="PDUR_RS09540"
                     /old_locus_tag="PDUR_09955"
     CDS             complement(8785..9576)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038196.1"
                     /locus_tag="PDUR_RS09540"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="PDUR_09955"
                     /product="EFR1 family ferrodoxin"
                     /protein_id="WP_042206069.1"
                     /transl_table=11
                     /translation="MIFYFSGTGNSLYTAKSIALHNNEELVSISAAVNTGNEWFEYSLK
                     DNERIGFVFPIYAWGPPKLVLEFIGKLKLNQYRDNYIFSVATCGGNIGNTMKIMDGRLK
                     KKGMHLNGRFSIKMPNNYILMGDVDSEKVEKEKRLAAEETLKRINPTIEQRTSGEFGLD
                     KGFFSWLLTGVVNPMFNKNAMNTAKFYVNDHCTGCGICEKVCNCNTIHLVNKKPQWGKR
                     CAQCLACIHYCPSKAIQYGNGTEKKGRYTHPQISIHEISMK"
     gene            complement(9610..9804)
                     /locus_tag="PDUR_RS27890"
     CDS             complement(9610..9804)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016121.5"
                     /locus_tag="PDUR_RS27890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FMN-binding protein"
                     /protein_id="WP_081949453.1"
                     /transl_table=11
                     /translation="MSSGKVTQIALLKNTEGRPSEFTNELYDKVIQSQSLQVDTISGAT
                     ITSKAYLKAVEDALLKAQK"
     gene            9811..9993
                     /locus_tag="PDUR_RS27895"
     CDS             9811..9993
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PDUR_RS27895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_081949454.1"
                     /transl_table=11
                     /translation="MNFIGGAIDSSLGGWSYAHGGWRFTSLIGIVMPLLALLYFLTEKR
                     TWAKDIETLADGLGQ"
     gene            complement(10001..11923)
                     /gene="shc"
                     /locus_tag="PDUR_RS09545"
                     /old_locus_tag="PDUR_09960"
     CDS             complement(10001..11923)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348568.1"
                     /locus_tag="PDUR_RS09545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09960"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_042206071.1"
                     /sec_met_domain="T2TS (E-value: 3.3e-101, bitscore: 337.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSILSKIDEAIDHLTSTLIRQQHPDGAWHFCFENGTAIDAYVII
                     LFRTLNIQSEALIRQLHDRILAGQQPEGCWKLYSDEEEGNLSASIEAYYALLYSGYSQL
                     TDEPIQRAKHFIQSKGGLRKVTSTLTKAILAATGQIKWPASISSIPLEVMLLPPSVPIN
                     IFEFSGYARVHLAPMLIMADRHFSMKTAQTPELHDLHVNRINTGEQHSREHQEALDSIR
                     SGLNRFIGSPRSIHDAAVKKAEQFILQRIESDGTLYSYASSTILMIFSLLALGYDKHHP
                     LITDATQGIKAMHWSFDGKTTIQNSPSTVWDTALVAYAMQESGVPDDHIAIRRAAVYLL
                     SRQHHKTADWTIHNPDIPPGGWGFSETNTINPDVDDTTAALRAIKSLSRTDPSCRESWN
                     RGLNWVLSMQNEDGGWPAFEKNTNKEILTWLAIDGAKSAAIDPSEADLTGRTLEYLGNF
                     AGLDNRYKFIQRGTQWLIKHQEKDGSWYGRWGICYIYGTWAALTGLRATGISSNHEALQ
                     KGAKWLLSIQNADGGWGESCSSDRLLRYVPLGDSTPSQTAWALDALIAVHPQPTAEINK
                     GIYRLIASLQEDKWMTTYPTGAGLPGSYYSHYHSYRYIWPLLTLSHYRKKYEPGRLEIQ
                     LRYTP"
     gene            12096..12512
                     /locus_tag="PDUR_RS09550"
                     /old_locus_tag="PDUR_09965"
     CDS             12096..12512
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019912088.1"
                     /locus_tag="PDUR_RS09550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09965"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_042206072.1"
                     /transl_table=11
                     /translation="MSIKDREEAVHNVMNQMAAVQQNSQAFIERIIKPGSLTQNQIMLL
                     MQLRLSGSLTITDVAEWFAVTPGAASSMCDKLEDLGLLQRMRTREDRRVVTIVLTEQGG
                     QRILDLFNDFEASELMKISETLEKINHLMAEIAH"
     misc_feature    12633..12646
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.98"
                     /tool="antismash"
     misc_feature    complement(12769..12785)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.18"
                     /tool="antismash"
     gene            13185..13778
                     /locus_tag="PDUR_RS09555"
                     /old_locus_tag="PDUR_09970"
     CDS             13185..13778
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014369570.1"
                     /locus_tag="PDUR_RS09555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09970"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_042206073.1"
                     /transl_table=11
                     /translation="MKQEERREQTIGQLLNATKELLRDRGCHGITMKDIMEKSELSKGA
                     IFHYVKSKDEIFAWVLQERLEEINKYFMNEVIQAPTTFDGPMQVISRNLEALEDANDVT
                     NKVLMYLLGKEDEPAVAEVLKNYYERSVYLSKEWIVSGQRHGVILESVDPDKTAEMFVL
                     LSLGLRVRSSFPIKNTSATAQDLSAYMVSILKDQ"
     misc_feature    13199..13214
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.84"
                     /tool="antismash"
     gene            13799..14254
                     /locus_tag="PDUR_RS09560"
                     /old_locus_tag="PDUR_09975"
     CDS             13799..14254
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013915706.1"
                     /locus_tag="PDUR_RS09560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09975"
                     /product="DoxX family protein"
                     /protein_id="WP_042206074.1"
                     /transl_table=11
                     /translation="MAPFIALVASFLLFRLIGLLGLSFFDNWHTSLQGAVAIMFLLTAS
                     AHWGKRRSDLIRMVPTVFPRREWIVTATGLLEIAGAIGIMLPRTSLAASIGLTLLLIAM
                     FPANVYAARNKLTIGGKPVPKLLVRTLLQILFIAAVLLASPISSSLQ"
     gene            complement(14425..15348)
                     /locus_tag="PDUR_RS09565"
                     /old_locus_tag="PDUR_09980"
     CDS             complement(14425..15348)
                     /NRPS_PKS="Domain: PKS_ER (17-302). E-value: 9.3e-52.
                     Score: 168.0. Matches aSDomain:
                     nrpspksdomains_PDUR_RS09565_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.5"
                     /locus_tag="PDUR_RS09565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09980"
                     /product="medium chain dehydrogenase/reductase family
                     protein"
                     /protein_id="WP_081949455.1"
                     /sec_met_domain="ADH_N (E-value: 7.9e-13, bitscore: 46.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-15, bitscore:
                     55.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METNKRIVVSRFGGPEVLELIEEPMPKPKKNEVLIRSLVTGVAFG
                     DIILRKGEAPFQKPPLTPGTEIVGIVTEVGPNVTTVKVGQLVAALPFFGGYTEHICLHQ
                     KELIPIPDGIDPKEAASLVLNYLMAYQLLHRYAHVQKGEKVLIHGASGGIGTALLQLGR
                     IADVEMFGTASQAKHAYVLSLGATPIDYKNTDFVREIKKYHPDGMDVVFDCMGGINFKK
                     SYQILRKEGRVIGYGSGHLLHTIMTIMSRKFIPDGRRASLYFLILSKKTKPHWFKEDLN
                     TLFELLRNRTFQPIINQIFPLCSSRT"
     aSDomain        complement(14443..15297)
                     /ASF="ER domain putatively catalyzing 2R-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PDUR_RS09565_PKS_ER.1"
                     /evalue="9.30E-52"
                     /label="PDUR_RS09565_PKS_ER.1"
                     /locus_tag="PDUR_RS09565"
                     /protein_end="302"
                     /protein_start="17"
                     /score="168.0"
                     /tool="antismash"
                     /translation="LELIEEPMPKPKKNEVLIRSLVTGVAFGDIILRKGEAPFQKPPLT
                     PGTEIVGIVTEVGPNVTTVKVGQLVAALPFFGGYTEHICLHQKELIPIPDGIDPKEAAS
                     LVLNYLMAYQLLHRYAHVQKGEKVLIHGASGGIGTALLQLGRIADVEMFGTASQAKHAY
                     VLSLGATPIDYKNTDFVREIKKYHPDGMDVVFDCMGGINFKKSYQILRKEGRVIGYGSG
                     HLLHTIMTIMSRKFIPDGRRASLYFLILSKKTKPHWFKEDLNTLFELLRNRTFQPIINQ
                     IFPL"
     CDS_motif       complement(14866..14925)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PDUR_RS09565_0002"
                     /evalue="6.20E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="PDUR_RS09565"
                     /protein_end="161"
                     /protein_start="141"
                     /score="25.0"
                     /tool="antismash"
                     /translation="GEKVLIHGASGGIGTALLQL"
     CDS_motif       complement(15124..15159)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PDUR_RS09565_0001"
                     /evalue="4.40E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="PDUR_RS09565"
                     /protein_end="75"
                     /protein_start="63"
                     /score="10.1"
                     /tool="antismash"
                     /translation="GTEIVGIVTEVG"
     gene            15488..16069
                     /locus_tag="PDUR_RS09570"
                     /old_locus_tag="PDUR_09985"
     CDS             15488..16069
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="PDUR_RS09570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09985"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_042206075.1"
                     /transl_table=11
                     /translation="MNGFEKRRQQKRDSILNAALELFKQYGYHKVSIAEIAKAASVAES
                     SIYNFFSNKENLKLELMRKLMYEDCTRTMNISSSHDPVQLKLEKLLMSKITLFKNFSVH
                     FPLESSGMGIITEELSEDENYHNAILNLIEDGKREGVFIESITTNAMAAYFDIIRYYFI
                     HNPDSTAIFDNNPEFAREMYSLFLNALLKR"
     gene            complement(16198..16374)
                     /locus_tag="PDUR_RS09575"
                     /old_locus_tag="PDUR_09990"
     CDS             complement(16198..16374)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041682.1"
                     /locus_tag="PDUR_RS09575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09990"
                     /product="small acid-soluble spore protein H"
                     /protein_id="WP_042206076.1"
                     /transl_table=11
                     /translation="MNTQRAQEIAASPIMEHVTYEGTPIYIQHVDENTGMARIYPLDRP
                     ENEQTVPVRSLIE"
     gene            16537..17592
                     /locus_tag="PDUR_RS09580"
                     /old_locus_tag="PDUR_09995"
     CDS             16537..17592
                     /GO_component="GO:0030115 - S-layer [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012613.5"
                     /locus_tag="PDUR_RS09580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_09995"
                     /product="S-layer homology domain-containing protein"
                     /protein_id="WP_042206077.1"
                     /transl_table=11
                     /translation="MRPKLHRITLFLLLPLFLIFTSFPPSAHAAETALLDKYYPADIEG
                     HWANDAIDNFVNANWLNGYADADGTILIKPNNNVTRAEFVTILVGAAGLTSSQSGKTFT
                     DVKAGKWYADPIRIASSLGIVGGITNTEFGPDRPITRGEIAVMVVNAFSSSVKFDGQPK
                     TFTDVPQYYAKPAIQKASQAGIVAGMTETEFKPFSRATRAQAVVMLERSLKLQQGNLPL
                     EQDLIDLAVKADKEETQLMVDKKYAELERIFLKYYTGYQFAYSMSSLKEINEMAAGGGT
                     LDIKVVKAPTFRVTERSDRLVVLDSVYGEVEMKISNGVNTYEETIKTDGQYLMKKMPDN
                     SWKIYAILTKE"
     gene            17785..19248
                     /locus_tag="PDUR_RS09585"
                     /old_locus_tag="PDUR_10000"
     CDS             17785..19248
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /locus_tag="PDUR_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_10000"
                     /product="PAS domain S-box protein"
                     /protein_id="WP_042206078.1"
                     /transl_table=11
                     /translation="MEKISKIQLPQHSLYSYLEYSPDAIYILDLNKKVVYVNPSFIKLF
                     GWSKDDLYELNFPHIPSELYNEWAGIFQHFDHKKEAVTLDTVRKKRDGELISISITISP
                     LMEPDGPITAFLCLSRDVTENKMSEQKYYRLFNQANDSIFIFEYNDQGKVSNFIDVNDT
                     ACQRLGYSRQELLAKSPPDIGDPSLADQFDLSFRSIVQGKTTFIEWIHVAKDGTRIPVE
                     INSKIFKLNNKNMVIAIVRDLTERKRTEELLRKSESFSLIGELSAGIAHEIRNPLTSIR
                     GFAQLLFSETESIQSYRDLVISEVDRINSIIGELLFLAKPQSSDLIDKDLITLLRQTIT
                     LLNAQAHLTENEIVMESNPGSLYIRCAENKLKQVFINILKNAIEASPRGAGIKVEVIRR
                     KQNVLVRFLDQGKGIPAEILSQIGSPFFTTKSGGTGLGIMISQKIIQDHHGTLHFAANQ
                     PKGTIVEVMLPIKKYRESKMEHNVSQSID"
     gene            complement(19299..19958)
                     /locus_tag="PDUR_RS09590"
                     /old_locus_tag="PDUR_10005"
     CDS             complement(19299..19958)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019914716.1"
                     /locus_tag="PDUR_RS09590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_10005"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_042206079.1"
                     /transl_table=11
                     /translation="MSDQGTSSNTNTRKLKTYQEARLQNIENLRKLVVDAAATLLQEEG
                     PEAVTVRRVADKMDCSTKIIYSLFVNKEGLAQQLYLEGCKILADEFEGTPQAADPAQYL
                     LNFGETFWEFGQRYSSYYKLMFGGAFADFKPDEESMQGTVTAMQQLLTVISNAQEQVLI
                     PSQYDTESVVRIFWASLHGVIHLYMGGHLGDVESAYAIYRKTLSLIVSSLFQARSS"
     misc_feature    complement(20179..20196)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.27"
                     /tool="antismash"
     gene            20236..21081
                     /locus_tag="PDUR_RS09595"
                     /old_locus_tag="PDUR_10010"
     CDS             20236..21081
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-169). E-value: 2.7e-10. Score:
                     32.4. Matches aSDomain:
                     nrpspksdomains_PDUR_RS09595_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010495409.1"
                     /locus_tag="PDUR_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PDUR_10010"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_407944316.1"
                     /sec_met_domain="adh_short (E-value: 2e-32, bitscore:
                     111.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEIKGKWSLVTGASSGIGEQFARQLAKQGSHLVLVARSKSKLEE
                     LASELRKRYGIKAEVIPLDLAKEGAPSELYQQCRLLKVEIELLVNNAGFATHGLFEQVS
                     GERQHEEVMLNVTAVVDMTHLFLPDMLRKSSGAVINVASTAGFQPLPYMAVYGATKAFV
                     LSFTQALYWENRDRGVKFFALCPGSTDTSFFNVVGAEEASVGKKDTPERVVEIALRALK
                     EGKLYVVPGMQNYMGAQLSRFITRKQGLRLVGNMLRPREGSGNYKNNGNQSDLAGRTNQ
                     "
     CDS_motif       20263..20352
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PDUR_RS09595_0001"
                     /evalue="5.10E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="PDUR_RS09595"
                     /protein_end="39"
                     /protein_start="9"
                     /score="22.4"
                     /tool="antismash"
                     /translation="LVTGASSGIGEQFARQLAKQGSHLVLVARS"
     aSDomain        20263..20742
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PDUR_RS09595_PKS_KR.1"
                     /evalue="2.70E-10"
                     /label="PDUR_RS09595_PKS_KR.1"
                     /locus_tag="PDUR_RS09595"
                     /protein_end="169"
                     /protein_start="9"
                     /score="32.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGASSGIGEQFARQLAKQGSHLVLVARSKSKLEELASELRKRY
                     GIKAEVIPLDLAKEGAPSELYQQCRLLKVEIELLVNNAGFATHGLFEQVSGERQHEEVM
                     LNVTAVVDMTHLFLPDMLRKSSGAVINVASTAGFQPLPYMAVYGATKAFVLSFTQA"
ORIGIN
        1 aatgatttgt atacctatat gagtgagaag tccgaatcgg tctctcaggc gatgctgctt
       61 acgctggttg ggcggtacat cgagcggatc gccgatcatg cgaccaacat tggggaaagc
      121 gttgtttact tggtaacagg taaacgtccg gatttaaata tgtagtaaac ggccaggccg
      181 tttggtgaat acgccgaata tgtttataag agaaagcgca tcattgccgc taagcggtga
      241 gggcgctttc ttcttttttc acagaatgtg taagctttga agccgctaat ggcactttga
      301 tgggctattt tgccgggccg tgtggtaaga tgtaaaggat aagcaataaa agacgaggtg
      361 caaaatggac aagctgattc ttatagatgg aaataatgtc atttaccgtg cattcttcgc
      421 catgcctccc ctgactaata cagcagggca gcagaccaac gccgtgtacg gctttactac
      481 aatgctgctt cggctgattg aggagcataa accgacgcat ctgatcgtcg cgttcgacgc
      541 ggggaaggtc accttccggc acgaaggtta ccaggagtac aaggggggcc gtcagaagac
      601 gccgcccgag ttgtcggagc agttcccgct cctcaaaggt ctgcttagcg acctgggcgt
      661 gccgcagttt gagattgaga actatgaagc ggatgatatt atcggcagta tctcccggca
      721 ggcggacgaa gcgggacgcc aggtgatgat cgtatcgggg gataaggaca tgctgcagct
      781 ggcgtcggag catacgacca ttgcgctgat tcgcaagggt gtcaccgata tcgagctgta
      841 tggaccgaag cagatccgtg ataagtacga tttgacgccg cagcagatca tcgacctcaa
      901 agggctgatg ggcgatgcga gcgacaatat tcccggcgta ccgggtgtcg gcgagaagac
      961 tgccctcaag ctgcttgccc agttcggctc cgtagaggga gtgatcgcgg gaacaggcga
     1021 gctgaagggc aagatgaagg agaagctgga ggcgcatgcc gacgacgcca ttatgagcaa
     1081 aaagctggcg accatatacc gtgaggttcc gctgacacat tcctgggagg atttggcttt
     1141 ccatggtctc aagaaagaca cagccggacc tgcgctggcg aagctggaat tcaagtcact
     1201 gctcgagcgc ctttccttga gcgggagcgc ccccgtgaac gaagagtcgt cctccaaagc
     1261 ggtgcagctt gacatcgtca ttgctggtga gccggagctt gaagagctta cggccgcgct
     1321 gacggatgtg aaggcgctgc atgtggagac gaacggcgag aacccgcacc gggccgaggt
     1381 aatcggcctg gcgctatcgc tgctggagcg gcattatttt gtgccgttcg agctgctgaa
     1441 gagcggcgcc gcggcgggct tgcgcgattg gctggccgac gagcatgcgc cgaagaacgg
     1501 ctacgacctg caccgcgcgg acttggcgct gcactggcag ggcatcccct tcgccggggc
     1561 ggcgcatgat gtgcagctcg cagcatatct gctcgacccg accgaggcca accagaacct
     1621 cagcgacctt gtcgccaaat acggcctgcc gcgccttgcg ccggacgaag aagtatttgg
     1681 caagggagcc aaatacaaag tgccggagct ggacattctg ggcgcgcatg tcgcctcgaa
     1741 gagcgcgtct gtgcttggcc ttgtaccgaa gcaggagcag gatctgaccg aaacagccat
     1801 gtccgggctg ttccacgatc tggaaatgcc gctttcgcgc attttggccg acatggagaa
     1861 acaggggatt gccgtcaata tggacggtct caaggagctg ggccgggaat ttgagagcac
     1921 gatctcgggc ctcgttgagc aaatctatga aatcgcgggc acggaattca atttgaattc
     1981 gacgaagcag cttggtgaga ttttattcga taagcttgga cttcctgtta tcaagaagac
     2041 aaagaccggc tattccaccg atgctgaggt gctggagaag ctggagcctt accatgaaat
     2101 cgtacaaaag attttgcagt accgcacgct cgcgaagctg cagtccactt acgtggaagg
     2161 gctgctgaag gaaattgccc cgtcgacggg caaggtgcac accttctacc gtcagacgat
     2221 tgcggcgacc ggacggctga gcagccagtt cccgaacttg cagaacatcc cgatccggct
     2281 ggaggaaggc cgcaaaatcc gtaaagtatt cgtgccctcc gagccaggct ggtcgattct
     2341 ggcggccgac tattcgcaga ttgagctgcg ggtgcttgcg catatttcgg acgacgcaag
     2401 gctgaaggaa gcctttttgc atgatatgga tattcatacc aagacggcca tggacgtatt
     2461 cggcgttcct gccgaagcgg tcgacggcaa catgcggcgc tctgccaaag cggtcaattt
     2521 cggtatcgta tacggtatca gcgattatgg cctttcccag aacctgaata ttacgcggaa
     2581 ggaagccgga aggttcatcg agcagtattt cgaggtgttc cagggcgtac gccgatatat
     2641 ggacgagatt gtccgcgaag cgcgcaaagc gggctacgtc actacgctgc tggaacgccg
     2701 acgttatctg ccggagatca atgcgagcaa ctttaatctg cgttcttttg ccgagcggac
     2761 ggcgatgaat acaccgattc agggaaccgc agccgatatt atcaagctgg cgatgatcca
     2821 tatggaccgg gccctgttcg agcgtaagct gaagagccgc atgctgcttc aggtgcatga
     2881 cgaattagtg ttcgaggtgc cggaggacga gctggaaacg atgaaaaagc tcgtgcctga
     2941 agttatggaa ggcgcgctga agctgtcggt tccgctcaag gcggaggtaa gttatggaag
     3001 taactggtat gaagcaaaat aaaagccccc gcatgccttg cttatccggt ataatggagt
     3061 agaggtgaag acatcatgcc ggaattaccg gaagtagaga ccgtcaagag aacactgaac
     3121 accttggtgc aaggaaaaaa gatacagaaa gtcaccgtcc ggctgccgcg tattatccgg
     3181 cgtccggacg atattcgagt atttgaaact atgctggaag gccatacgat cgagcgtgtg
     3241 gagcgccgcg gcaaattttt gcgctttctg ctggacggtc tggtgcttgt ctcccatctg
     3301 cggatggaag gccggtacgg attgtatgct gcggaagagc ctttagataa acatacacat
     3361 gtgatttttc attttgagga tgggactgag ctgcgctata cggacgtaag gcagttcggc
     3421 accatggatt tgttcctgcc tggagatgat ctcagccttc ctccgctgaa caagctggga
     3481 ctggaaccgc tggacccgga atttacaccc gaagcgttta aggatctggt agccgggaaa
     3541 aatacaaaaa tcaagcctct gctgctcaat caggcatatg tggtcggcat cggcaatatt
     3601 tatgtggatg agtccctgca tcgggccggt attcatccgg agacggctgc caaatcactg
     3661 actgcagagc aactgaaccg gctgcatcag gcgattgtcg ccacgctgac ggaagcggta
     3721 aatgccggcg gctcatccgt caaatcttat gtgaacggcc agggagtgag cggaagctat
     3781 cagcacaagc tgctgatcta cggccgcaaa gatcaagcct gttattcctg cgggtccgtg
     3841 gttgagaaga gcgtagtcgg cggacgcggg acgcattttt gtccaagctg ccagccgctg
     3901 cttttaatgt gaagacctct gcttaggatg aagattttgt aggcaaaagc cgtattttgc
     3961 gggggagttt ttcgctgaat tcctccggtt ttcttcgcgt tttacattct ttcataaagg
     4021 ttgacaccca tagcccatac cgcccatata ctgtgtgaag aatgctacat ttgtgactcg
     4081 acgacttccg tctttatgca tcggaggttt cggttcttca cgggagggat tgcgggtgat
     4141 cagccccatt ttttcactgc tgctgttggc atttgctctg agtctggacg gtttcggtgt
     4201 cggcattaca tacggattgc gcaaattgaa aatacctctg ccctccgtac tcattatctc
     4261 gctctgttcc ggagttgtga tgtgcgtctc gatgcaggtt ggcgtgctgc tgtccaaagt
     4321 cgtctcgcca catatcgctt ccctgatcgg ggcggtgatt atccttatca tgggctgctg
     4381 gtcgctggta cagctggtag tgcaaaggga tgatgagaga acggaagggg aaactggcgg
     4441 gatgccggga aacgcggaaa atcaaagccc ggatggcctg gcagtaacgg ataaaactcg
     4501 ggaggaagat ccggagaaat ctgcggtgtt ttccctggag ctgcggcggc tcgggattgt
     4561 tgttcaaatc cttcgcactc cgtcctcggc tgacatggat aaatcgggca gcatttcccc
     4621 ggtagaggcg cttgtgctgg gcgtcgccct atcgctggac gctttcggaa caggccttgg
     4681 agctgcgctc cttggattta atccgctttg gacgtcgctc gttatcgccc tgttcagcgg
     4741 cagtatattg cttctggggc tccatacagg gctgcgtttt gccggaacct cctggatgaa
     4801 gcacgcttcg gtgctgccag cgctgctctt gattgcaata ggaatattga agctgttatg
     4861 aggtgaaaac atgattatgg gcttaaccgg gggaattgcc tccggaaaaa gcaccgtgtc
     4921 cgcccttctc atcaagaagg gggcaaggct cattgacgcc gatgccattg cccgggagat
     4981 catgctcccc ggacacgaag tgctggccgc cgttaccgaa tattttggcg aggggatact
     5041 tcttcctgac gggacgttga accgcacgaa attaggagac atcgtctttc acgatcctga
     5101 agccctgaag gctctgaatg gactgaccca tccggtaatc cgaagggaaa ctagggagcg
     5161 gatgcaggca atggaacggg aaacgcctga gcgattgatc atcgttgata tcccgctgct
     5221 cttcgagtcg gggctggatg atatgtttga acggatcttg gttgtttatg ctccgcgaga
     5281 ggtacagctt gagcgtctga agagacggaa cgggttaacg caggatcagg ctgaggcccg
     5341 gctgaactcg caaatggata ttgagctcaa gcgctccaaa gccgactaca tcattgataa
     5401 cagcggggat cttgccgata ccgagcggca gatcgccgtt ttgtgggaca ggctgggtct
     5461 tccatgctga aatggctcct gaaaaaaaga gtgctgctgc tgttatttct cggctttacc
     5521 gccatattgt ttctcagcac gaactggatg tcctggtttt atccgattta ttttaaggaa
     5581 gaaattcgca agcacagctc cacgtatcag gtcgacccct atcttgtggc ggcaatcatc
     5641 cgggtggaga ccaatttcaa gaccggacgc gagtcgaaaa aaggagcact cggacttatg
     5701 cagctgatgc ccgatacagc taagtgggcg cttgaacagg ccaagctccc tgatgtatcg
     5761 atgagccgtc tcaagaacga gccttcagcc aacattgagc tgggcgcctg gtatttacat
     5821 tccttatccg ggcagttcga cggcaaccgt acagcggtca ttgcggccta taatgccgga
     5881 cccggaacgg ttcagcgctg gctcgcggat ggttcatgga acggaagcca agaggatatc
     5941 aaaaatattc cgtttggcga gacccgccac tatgtacagc gtgtcattta ttactacaat
     6001 caatatacgg agatctacgg gggcgtgttt tagctgtaca ttaagcgatg ccatgagaaa
     6061 agaagtgccg accggccgtc tggaccgttt ggcacttctt cggcaagctt atgttggcag
     6121 attattggaa ttgacctgcc agttgttgtt cagccagggt taccagacgt ttcgtaatgt
     6181 aacccccgat cgaaccgttc tcataagaag ttttattgcc ttgatatcca tccggagaaa
     6241 gagtgatacc aagttcttgg gcaacttcat atttcagttg ctccaaagcc gcattcgctc
     6301 ttggtacgac aaggttattg gtgctggatt gaccattgct tgcttgtgcc atttctgttc
     6361 acctcctatc ggttggtaac tgtattatgc gccggacttg ccgcattcat tacttattat
     6421 caaaggtgtt ttctggaaaa ggaataccca taatcttagc aaaggaagtg atcggatcat
     6481 gaaatgccca tactgcgacc atactaacac taaagtgctt gactcccgtc cggccaatga
     6541 aaataaatcg atccgccgca ggcgggagtg cgagaggtgc agccggcgct tcaccacctt
     6601 cgagatggtg gaagaaaccc ctctgatcgt tatcaagaaa gacggaagcc gtgaagagtt
     6661 cagccgggac aaaatacttc ggggcctgat ccgcgcctgc gagaaacgac ccgtatccgt
     6721 cgagcggctc gagatgatcg tctccgaggt tgagaaatcg ctgcgcggca tcgcggtagc
     6781 cgaggtcgag agccagcaga tcggcgaact cgtgatggaa cagctctatc cggtggatga
     6841 agtcgcttac gtccgcttcg cgtccgtgta ccgccagttc aaggacatca atatgttcat
     6901 gaaggaactg aaggcgctct tgtccaaaaa tccggcggag acggaaggac tgtaagccca
     6961 ggcttaacag tccttttcgt ctatcgcata ttcctattga tacggtaatc ttatttggtc
     7021 tccaacaatt ttcaaaaaaa ctgttgacat gggtctcgta attttatatg atatagaagt
     7081 cggctgcggg acaacatgat gcggaacatc aagaagaagc cgatttatac atatcggata
     7141 tattaacatg gggccttagc tcagctggga gagcgcatcg ctggcagcga tgaggtcagg
     7201 ggttcgatcc ccctaggctc cataaagatg aagagtctca ctccaaggag tggggctctt
     7261 cttcatctac atggttttgg ggtccgaacc cgaagggttc gcccgggcgc aggaatcgcc
     7321 agcgtacgag tacggttgtc tcattccacc atagcgatct gcttcgtcga gttcacatca
     7381 tccatttata cgtatatatt gacaaagatt ccagcttata atactataat tatagtttat
     7441 aaaacttata aaaatactag gtataaatat atttttagag aatataatgc tgaagattat
     7501 ctaaaacttt ataaaaaagt tgaccagaat actggaggca aagcattact atctattgtg
     7561 gatagggctt tgcctcttta attttaaata atggaactag aatagggaag gagtttttat
     7621 tgtgaacttt aataaaataa aaacgatgat atttgaatca agacggctac taggtgtagc
     7681 agtgtttttg ctgatttggg aaatatcacc tcggttggga tgggtggatc aatcttttct
     7741 tcccccattt tctaaggtga taacaaccct tatttcactt attttatccg gagagcttga
     7801 gaaacatatc ctgatcagtc tgcagcgctc attgttaggt tttgggttgg gactgctgat
     7861 agcgattccg ttaggattga ttattggctg gtttaaagga ttcgaatttt atatggaccc
     7921 tttattgcaa actttcaggc agacttcaac catcaagcca ggtcatatgc agtttattat
     7981 tttctgggct gtcaaccata ctgtgcagta caatttttat ttttgcgcct gctttacggg
     8041 cgacggcgat attggtcgga tgcccggagc caaacagatc attatctcct ttaataacgg
     8101 attgggctag atttgagcct tgggccagaa ctccggtata taccggtttg atattcactt
     8161 ctttgaaaaa gcctttcaag tcagcaatga taaattcgtt gaatccggta aaagtcggtg
     8221 ttttgagctc gaattccttt gttaattttc cattcacaaa tttcggttct tcgctgtctt
     8281 tcgatgggga agatgttgaa ttcccacagc ccgcaagaaa gagagttaat aatacgatgg
     8341 taagtgtaag cagtaagccg attgtttttt tcatttcatt acgctccttt ataaaaaaat
     8401 aatttaaaag aaagaggctg gatatataaa tatccagcct ctagctttct agttagccaa
     8461 tttaattcct actaaacata tgtaatttat gagtaccgtt aaaaaatata acattcaggt
     8521 atttttttgt caattactag attaaaatat tataatgatg gagtgaacta acgatagtgg
     8581 acttcaaaat tttttatcga atatattggg gttaaaagag tcgtgaagtg gcgacgtcgt
     8641 tatcaggtgt atgagaaatt tatgttgggg tccctcactt ttggcgaaca aaggagtaag
     8701 ggacatcacc atcccgttca acgtgaaaac cataaagaca gacggtccga taaacgaccg
     8761 gaaatgggta tggttgagct caatttactt catagaaatt tcatgaatgc taatttgggg
     8821 gtgggtatat ctcccttttt tctcggtgcc gtttccgtat tgaatggctt tggatggaca
     8881 atagtggata cacgccaagc attgggcaca acgtttcccc cactgcggct ttttattcac
     8941 gagatgaatc gtattgcaat tacaaacctt ttcacaaata ccacagccgg tacaatgatc
     9001 attgacataa aattttgcgg tattcatcgc atttttatta aacattggat taacaacccc
     9061 ggttaacagc catgaaaaaa agcctttgtc taatccaaat tctcctgatg ttctttgttc
     9121 aatggtagga ttgattcttt tcaaagtttc ttcggccgcc aatcgctttt ctttttccac
     9181 tttttctgaa tccacatcac ccattaaaat atagttgttt ggcattttaa tgctaaatcg
     9241 accgtttaaa tgcatccctt ttttcttcaa gcgaccgtcc attattttca tcgtatttcc
     9301 gatgtttcct ccacaagtcg caaccgaaaa gatgtagttg tcgcggtatt gattcagctt
     9361 aagctttcct ataaattcaa gcaccaattt gggaggcccc catgcataga ttgggaatac
     9421 aaagccaatc ctttcattgt ccttcaggct gtattcaaac cattcatttc cggtgttaac
     9481 agccgcggat atggaaacta attcttcatt attgtgcaga gcaatacttt tagcggtata
     9541 aagggagtta cctgttccgg aaaaataaaa aatcatacct atcatcctct ctaatccata
     9601 ggtctattac tatttttgcg ctttgagcaa tgcgtcttct actgctttaa gatacgcttt
     9661 agaggtaatg gtagcaccgc taatcgtgtc cacctgtaaa gactgtgact gaattacttt
     9721 atcatacaac tcattcgtga attcagaagg tctgccttct gtattcttta acaatgcaat
     9781 ttgtgtgact ttgcctgaag acacggtaac ttgaacttca ttggcggagc aattgactca
     9841 tctttgggcg gttggtctta tgcccatggc ggttggcgtt tcacatctct aatcggtatt
     9901 gtgatgccgc ttttagcttt actttatttt cttactgaaa aaagaacctg ggcaaaggac
     9961 attgaaaccc ttgcagatgg tttggggcag tgaaactaat tcaaggcgtg taacggagtt
    10021 gaatttccaa tctcccgggt tcgtacttct ttctatagtg acttagcgta aggagcggcc
    10081 agatgtaccg gtagctgtga tagtgagaat aatagctgcc ggggagtccg gctcctgttg
    10141 gataagtggt catccacttg tcttcttgta atgaagcgat aagtctatag attcctttat
    10201 ttatttcggc tgttggctgt gggtggacag cgatgagtgc gtctaaggcc catgcggttt
    10261 gagaaggtgt gctgtctccc aaaggcacat agcgcagcag ccggtcgcta ctacaggatt
    10321 ctccccatcc tccgtcagcg ttttgaatac ttaatagcca tttggctcct ttttgtaaag
    10381 cttcatggtt ggaggaaatg ccagtagccc ttaagcctgt taacgcagcc cacgtgccat
    10441 agatgtaaca gattccccat cttccatacc acgagccgtc cttctcctga tgcttaatca
    10501 gccattgggt gccgcgttgg ataaatttgt accggttgtc tagcccggca aaattcccaa
    10561 gatactccaa ggttcgccct gtcaggtccg cctccgaggg atctatagca gcagatttag
    10621 cgccatctat ggcgagccaa gtgagtattt ctttgttggt gtttttctcg aatgccggcc
    10681 agcctccgtc ttcattttgc atggacagga cccaattaag accgcggttc catgattccc
    10741 ggcaggatgg atcagtacgg gataagcttt tgattgctcg taaagctgca gttgtatcat
    10801 ccacatccgg attgatggta ttcgtttctg aaaatcccca tcccccggga gggatatcgg
    10861 gattatgaat tgtccaatct gctgttttgt gatgctgtct ggagagcaga tacacagcag
    10921 cccgccggat cgctatatga tcatcaggga ccccggattc ctgcatggcg taagctacca
    10981 gagctgtatc ccatacggta gaaggcgaat tttgaattgt agttttgccg tcaaagctcc
    11041 agtgcatagc tttaatgcct tgagtcgcat cagtgatgag aggatgatgc ttatcatacc
    11101 cgagggcaag cagggagaag atcatcagaa tggtgctgct ggcatagctg tataaggttc
    11161 catccgattc aatccgctgc aaaatgaact gttcagcctt tttaacggca gcgtcatgga
    11221 tagagcgggg agagccgata aatctgttca gtccggatcg tatgctgtcc agagcctctt
    11281 ggtgttcccg ggaatgctgt tcgccggtgt tgatccgatt cacatgaaga tcgtgcagtt
    11341 caggagtttg agcggtcttc atagagaaat ggcgatcggc catgatcagc atgggggcaa
    11401 gatggactcg tgcataacct gaaaactcaa aaatgttgat tggaacagat ggagggagga
    11461 gcattacctc aagcggaatg gacgagatgg aggcaggcca tttaatttgt ccggtagcgg
    11521 cgaggattgc ctttgttaag gtgctggtaa cttttctaag accacccttg gattgaataa
    11581 aatgtttggc tcgctgaata ggttcgtccg ttagttggct gtatccggaa tagagcaggg
    11641 cgtagtaggc ttcaatcgaa gcggataagt ttccttcttc ttcatcggaa tacaatttcc
    11701 aacagccttc gggctgctgc ccggcgagaa tgcgatcatg cagttgccga ataagggctt
    11761 cgctctgaat gttcaacgtt cgaaagagaa tgattacgta tgcatctatg gccgtcccat
    11821 tctcaaaaca aaaatgccaa gccccgtctg gatgctgctg ccggataagg gttgatgtca
    11881 ggtgatcgat tgcctcatct attttgctta aaatgctgcc cattcacgtg gtacctccca
    11941 aatcattttt accattatat gcttggcggc aaaaggtaat tgcgattttt aacgatagta
    12001 agaggaacgc agagaacaaa caatctgcaa ggaggattga caataaaatt ataatttcta
    12061 tatattttaa gtactaaact aaatggagtg ttgtcatgag catcaaagac agggaagaag
    12121 ccgttcacaa tgttatgaat caaatggctg ctgttcaaca aaattcgcaa gctttcattg
    12181 aacggattat taagccaggt tcgctgaccc aaaaccagat tatgctgctt atgcagcttc
    12241 gtctttcggg aagcctaacg attaccgatg tagccgaatg gtttgccgtt acgcccggag
    12301 ctgcttcttc gatgtgtgac aagctggaag atctcggtct tctgcaaaga atgcggacga
    12361 gggaggatcg ccgggtcgtt acgatcgtgc ttacggaaca aggcgggcaa cggatccttg
    12421 atctgttcaa cgatttcgag gcttcggaac ttatgaaaat ctccgagaca ctggaaaaaa
    12481 taaatcacct gatggcagaa atcgcgcatt aaatgcaccg ctaatattgg aatacaaatg
    12541 aaagtactgc acaccaaact cacgggtgtc agtacttttt tgttgaggaa actaatttat
    12601 tttattgaat ataatttata gttgttatat attttaatta ttaaaataaa ttggcgtgaa
    12661 aggagagcgg ttcgaatgtc caaaatgccg tactgctcga aaaataggag ggagctcgtt
    12721 gaaatacatc tataaagggc tgatcggatt attttgtatc cctattctta gcgtgtggtt
    12781 tgcaggaagt ctgatttgct ctgtgactgc tgtcattgta ggggttcttc gttcctttgg
    12841 aattagggga atcggcatga ccatctatcc tgggttttct gtgccggaat ctctcagcct
    12901 gccttttggg ttgtgcctgg ctgctgtgtt gatgatttca ttcctttata ccaggcgctt
    12961 ccttcggaga tgtctccttt acttacgaac accataacga tttctattga gataaaacat
    13021 ctacgcagcc tggtaagggt tgcgtttttt agcgattcag acagtatcac cgatccctac
    13081 ggaatcacct tcgaaaataa tgatatttac aaaccgatgg tcggtttata taatgaggtt
    13141 attagcagca ataaattttg ttaaacgatt atggaggaat cactttgaaa caagaggaac
    13201 gccgagaaca aacaataggg cagctgctta atgcaactaa ggagctattg cgggatagag
    13261 gctgccacgg tatcacaatg aaagacatca tggaaaaatc agagttatct aagggggcta
    13321 tcttccatta tgtgaaaagt aaagacgaaa tttttgcctg ggtgctgcaa gaacggcttg
    13381 aagaaatcaa caaatatttc atgaacgaag tgatacaagc cccgacaacc tttgatggac
    13441 cgatgcaagt aatctcgcgt aatcttgagg cattggaaga tgcaaatgat gtgacgaaca
    13501 aggttctgat gtacttgcta ggtaaggaag atgaacctgc tgtcgcggaa gtgctgaaga
    13561 attattatga gcggtctgta tatttatcta aggaatggat tgtgagcggc cagcggcacg
    13621 gggttattct ggaatcggtt gatccggaca agacggcgga aatgttcgtc ctgctatctc
    13681 tgggtctgcg cgtccgttct tcttttccca ttaagaacac ttctgcaact gctcaggatc
    13741 tatcagcata catggtcagc attttgaaag accaataatg taatacgggg ggattgatat
    13801 ggcaccattt attgcgcttg ttgcctcttt tttattgttc cggttgattg ggttgttagg
    13861 actgtctttt ttcgataatt ggcacacatc actgcaaggg gcggtggcta tcatgtttct
    13921 gctcactgct tcagctcact gggggaaaag gcggtctgac ctgattcgga tggttcctac
    13981 tgttttccca aggagggaat ggatcgtgac ggcaacggga ctcctggaaa tagccggggc
    14041 tatcggaatt atgctccccc gtacttccct agctgcttcg attggcttga cgcttctact
    14101 gatagcgatg ttccctgcaa atgtatatgc ggctcgaaac aaattgacga ttggcggcaa
    14161 gcctgtaccc aagctgcttg tccggacttt actgcagatc ctgtttatcg cagcagtcct
    14221 gttggcctcc ccgatctcat caagccttca atagcaccaa tagggatttt attttcgatc
    14281 tatactgccg tgtttgaaaa ataaagccgt ccggaacatg attttcatat tctggacggc
    14341 cgctttgtgt ttatgtaatg acggatttgc taagggttca tcgttaagag gatttttcct
    14401 gttacagtcc cgttctccaa catttcatgt gcggcttgag cataggggga agatttggtt
    14461 tataattggt tgaaaagttc gattacgaag cagttcaaat aacgtattca gatcttcttt
    14521 aaaccaatga ggttttgttt ttttagataa aattagaaaa tagagcgagg ctctcctgcc
    14581 atcgggtata aatttccgag acatgattgt cattatagta tgcaaaagat gcccagagcc
    14641 ataaccgatt acacggcctt cctttcgcaa aatttgatat gattttttga agtttatacc
    14701 gcccatacag tcaaaaacaa catccattcc gtcagggtga tattttttta tctcgcgaac
    14761 aaaatctgta tttttgtagt cgataggtgt ggcgcctaaa cttaatacat aagcatgctt
    14821 ggcttgcgag gcagtaccga acatttcaac atcagctatc ctgcctaatt ggagaagcgc
    14881 agtaccaatc cctcctgagg cgccatggat gagaactttc tctcctttct gtacatgggc
    14941 ataccggtga agcagctgat acgccatcaa atagttgagc acaagagatg ccgcttcttt
    15001 cggatcaatc ccatcgggga tcgggataag ctccttctga tgcagacaaa tatgttcggt
    15061 atatcctcca aagaagggga gtgcagcaac aagttgtccg acttttaccg tggtgacatt
    15121 cggccctact tctgttacga tgccaacaat ttcagtgccg ggtgtaagcg gaggcttttg
    15181 aaacggggct tctcctttcc gaaggataat atctccgaac gcgactcccg tcactaagct
    15241 cctgataagg acttcatttt ttttcggctt gggcatcggt tcttcgatca gttccaatac
    15301 ttcaggtcct ccaaatcggc taaccacaat ccgtttgttt gtttccatac ccttctagcc
    15361 cctctcgatt tatgtagtaa aaatattgtt ttactccata aattgatttt atattctatg
    15421 cgattgaaaa tcaatagtta tacagtataa tgatgtatat actccataac taaagaagag
    15481 ggttacgatg aacggttttg aaaaaagacg tcaacaaaaa agagattcta tattaaacgc
    15541 cgcgctagaa ttgtttaaac aatacggata tcacaaggtc agcatcgctg agatagcgaa
    15601 agcggcttcc gttgcggagt cctcgatcta taactttttc agcaataaag aaaatctgaa
    15661 gctggaattg atgaggaagc tgatgtatga agattgtacg aggacgatga atatttcttc
    15721 gagtcacgat cctgtccaac ttaagcttga aaaattgctg atgtccaaaa ttactttatt
    15781 caaaaacttt tccgtgcatt ttccactgga atcatctgga atggggatta ttaccgaaga
    15841 actttcagag gatgaaaatt atcataatgc aattcttaac cttattgagg atggaaaaag
    15901 agagggcgtg ttcatcgagt cgattacaac aaatgcaatg gccgcttact tcgacattat
    15961 ccggtattat tttattcaca atcctgattc caccgcaata tttgacaaca atccggagtt
    16021 tgccagggag atgtattctt tattcttgaa tgcattgttg aagagatagg tcaacaattt
    16081 tctaaatgat gaggtcaggg atcgatttcc taaggctcta ctcgaaaaag aagccgctgg
    16141 gcacataatg tccaaagcga cttcttatag caggaagtta aatccatttg atatttatta
    16201 ttcgatcagg ctcctaacgg ggaccgtttg ctcgttctcc ggccgatcca atggatagat
    16261 tctggccata ccggtgtttt catccacatg ctggatatag ataggagttc cttcgtaggt
    16321 tacatgttcc atgatcggcg aagctgcgat ctcttgagct ctttgtgtat tcattttctt
    16381 accctcctcc agttttcaga taacaacgat tagtgtcccg ctgaatgaag ggattatgca
    16441 taaaagttcc ggctagcaga tatttccgtt agagttaagc ttatgattct gctattctaa
    16501 gggacggaat atagaaatat taggaggaca tcccagatga gaccgaagtt acatcgcatt
    16561 actctttttc tgcttttacc cttgttcctg attttcacga gctttccacc gtcagcccat
    16621 gctgctgaaa ccgctctgct ggacaagtat tatcctgccg acattgaagg gcactgggca
    16681 aatgacgcga ttgataattt cgtcaatgcc aattggctga acggttatgc cgacgccgat
    16741 ggtacaatcc tcattaagcc gaacaataac gttacccgcg ccgaattcgt aacgattctt
    16801 gttggtgcgg cgggcctaac cagcagccag tcaggtaaaa cctttacgga cgtcaaggct
    16861 ggaaaatggt acgctgatcc gatccggatt gccagttcac tcggtatcgt cggcggcatc
    16921 acaaatacgg aattcggtcc tgaccggccg atcacaagag gcgagatcgc tgttatggtc
    16981 gtcaacgctt tttcatcatc cgtaaagttc gacggacaac ctaaaacctt cacggatgtt
    17041 ccgcaatatt acgcaaagcc tgctattcaa aaagctagcc aagccggcat tgtggccggg
    17101 atgaccgaga ccgaattcaa gccgttcagc cgcgctaccc gcgctcaagc ggttgtcatg
    17161 ctggaacgct ccctgaagct gcagcagggg aacctgccgc ttgaacagga tttgattgat
    17221 cttgccgtga aagcagacaa agaagaaaca cagctaatgg tagacaagaa gtatgccgaa
    17281 cttgagcgga tttttcttaa atattacaca ggctaccagt tcgcttacag tatgtcttcc
    17341 ttgaaggaga tcaatgaaat ggctgccggg ggcggaacgt tagacattaa agttgtgaaa
    17401 gccccgacct tccgcgttac cgaacgttct gaccgtctag tggtattgga ttcggtatac
    17461 ggtgaagtgg aaatgaaaat ttcgaacggt gttaatacct acgaagaaac catcaagacg
    17521 gacggccaat acctgatgaa gaaaatgccg gataacagct ggaaaatcta cgccatactc
    17581 accaaagaat aataggcaaa aatcggaggt tcatgagaat ctccgatttt ttgtttcttc
    17641 gatatgtgaa aaaagtaaat tcataaaaga agaataaaga gtacaataga agaaaagtgt
    17701 ttgctagaga gcatcaggaa ccctcactgg atagcgaata aacggtctga ttgaaatgta
    17761 aactggttac gggagttaag tcctatggaa aagatctcga agattcaatt gccgcagcat
    17821 tccttatact cctaccttga atacagtcct gatgccattt atattttgga tctgaataaa
    17881 aaagtggtgt atgtgaatcc ttcttttatt aaattgttcg gctggtctaa agatgattta
    17941 tatgagttga attttcccca tataccgtct gaattatata atgaatgggc cggcattttt
    18001 cagcatttcg accacaagaa agaggctgtt acgctggata cggtcagaaa aaaacgggat
    18061 ggtgaactga tcagcatcag cattacgatc tcgccgctca tggagccgga tggtccaatc
    18121 accgctttcc tttgcctttc gagggatgta acagaaaata aaatgtcgga gcaaaaatat
    18181 taccgcttgt tcaaccaggc aaatgactcc atatttatct ttgaatataa tgatcaagga
    18241 aaagtctcta attttatcga tgtgaatgac acagcttgcc aaagactcgg ttattccaga
    18301 caggagcttc tcgcgaagtc accgcccgat attggggacc caagtcttgc ggatcagttc
    18361 gatctaagtt tccgctccat tgtacaagga aaaacaactt ttattgaatg gattcatgtg
    18421 gctaaagacg gaacaagaat tccggttgag attaattcta aaatatttaa gctaaataat
    18481 aagaacatgg tcattgctat agttcgtgac cttacggaac ggaaaaggac ggaagagtta
    18541 ttaagaaaga gcgagagctt ttccctgatc ggagagctgt cagcgggaat tgctcatgag
    18601 atcaggaatc cgttaaccag tataagagga ttcgctcaac tattattttc tgaaaccgaa
    18661 tccattcaaa gttatcgtga tttagtcatc tccgaggtgg accggattaa ttccataatt
    18721 ggggagctgt tgtttcttgc taaaccgcaa agctcagatc taatcgacaa ggatctcatc
    18781 accctgctga gacaaacgat aaccttgctt aacgcccaag cgcatttgac cgaaaatgag
    18841 attgtcatgg aaagcaatcc ggggagtcta tatataagat gtgctgaaaa caagcttaaa
    18901 caggtcttta ttaatattct gaaaaatgcc attgaagcga gcccaagagg agccggaatt
    18961 aaagttgagg ttatccggag aaagcagaat gtattggttc gttttttgga tcagggaaag
    19021 ggtattcccg ccgagattct gagccaaatc ggttccccct ttttcacaac aaagtcaggg
    19081 ggcacgggac tcggaataat gatcagccaa aaaattatac aggatcatca tggaaccctt
    19141 cattttgccg ccaaccagcc gaaaggaacc attgttgaag ttatgctgcc aataaagaaa
    19201 tatagggaga gcaagatgga gcacaacgtg agccaaagta tcgattgaac atttggttct
    19261 aatttgggca actcgctcat tccctagcgg gatgcctttt agctgctacg agcttgaaac
    19321 aacgaactaa caatcaaaga caaagttttc ctgtatatgg cataggccga ttctacatct
    19381 cccaagtgtc cacccatgta tagatggata acgccgtgga gcgaggccca gaatatacgt
    19441 acaacggatt ccgtgtcata ctggctgggg attagtactt gctcttgcgc attgctgatc
    19501 acggtcaata attgctgcat ggccgttaca gtgccttgca tgctttcctc gtccggtttg
    19561 aaatctgcga aggctcctcc gaacatcagc ttataatagc tggagtaacg ctgcccgaat
    19621 tcccaaaagg tttcgccaaa attcagcaaa tactgtgccg gatcagcagc ctgcggcgta
    19681 ccttcgaatt cgtcagctag aatcttacaa ccctccagat acaactgctg agctaaacct
    19741 tctttattaa caaacaagct ataaatgatt tttgtcgaac aatccatttt atccgctact
    19801 cttcgcacag taacggcttc cgggccttct tcttgcaata acgttgccgc agcatcaaca
    19861 acaagcttgc gtagattttc tatattttgc aagcgagctt cttggtaggt tttcaacttt
    19921 cgtgtgttcg tattggagga ggtaccttgg tcgctcataa tcatcacctt cggttattat
    19981 gttttcgtta ggaaacaagg tttccgactc tcttatcaag aattttatat agttgttgga
    20041 cagttgtcaa tgtgcgttgg atgttcaaag atcatattga ctttccacaa aagggacgtt
    20101 acaatgaatt ccaatggaaa cactgttact gaaataatgc gacgattctt aacttttttg
    20161 ggaagttgag aattattttt aaccgctcgg taacaatgtt tccgaattaa aacgtagtat
    20221 ctgaaaggag gataaatatt ggaaataaaa ggtaaatggt cgcttgtcac gggagcttct
    20281 tccggtattg gagagcaatt cgcgagacaa ctggccaaac aaggcagcca tttggtactc
    20341 gtggcccgat caaagagcaa gcttgaggaa ctggcatcgg agcttagaaa gaggtatggc
    20401 atcaaagctg aggttatccc tttggatctt gcgaaagagg gcgcgcccag cgagttatat
    20461 cagcaatgtc ggcttttgaa agtggagatc gaactgctgg tcaacaatgc aggttttgct
    20521 acacatggtt tgtttgaaca agtgtcaggt gagcgtcagc atgaagaagt gatgctcaat
    20581 gtcacggctg ttgtagatat gacccacttg ttcttaccgg acatgttgcg caaaagctca
    20641 ggtgcagtaa ttaatgttgc ttcaaccgcc ggatttcaac cgcttcccta tatggccgta
    20701 tatggggcga cgaaggcttt cgtcttatcg tttactcaag cattatattg ggaaaatcgt
    20761 gaccgcggtg tcaaattttt cgcactttgt cctggttcga cggataccag tttctttaat
    20821 gtcgtaggag cggaagaagc ctccgtcgga aagaaagaca caccggaaag agtcgtagag
    20881 attgcgcttc gcgcgttgaa ggaagggaaa ctgtatgtcg ttcccggtat gcagaactat
    20941 atgggggcgc agttatcgcg attcattaca cgaaagcaag gtcttcggct tgttggaaac
    21001 atgcttcgtc cgcgcgaagg atccggtaat tataagaata atggtaatca atctgatctt
    21061 gcagggagga caaatcaatg aaagctgtac aactaacaaa cggcttcggc tttgaggaat
    21121 taactttgac ggaactcgac ataccaacgc ctggccctca ggaggtgctg atccgcatga
    21181 gggcagcttc tctcaactac cgggatttag tgatcctgaa tggattaatg ccggtcgaca
    21241 tcaagtttcc cttcattcca gtatcagacg gagcgggaga aattgtagct gtaggcccag
    21301 gagtaacaag atttcaggta ggacaccggg tagcgggtaa tttgcagcaa cgattcattg
    21361 ccggcaaccc aagagcggag gtattaggag aaagcctggc aggtccgttg aacggagtgg
    21421 cggccgagta tgtcgtcctg catgaaaatg gaatcgtccg tattccagat cacctcactt
    21481 gggaggaggc ctccacattg ccgatcgctg cattaactgc atggagcatg ctgatcgaat
    21541 acggcggttt acaagcgggt gataccgtgc tgctgcaagg aacaggcggt gtttccatct
    21601 tcggccttca attcgctgtt atggccggag caagagctat cattacatca agcagcaacg
    21661 ccaagctgga acgggcaaag gttctcggcg catggcaaac gatcaactat tcggaagttc
    21721 cagattggga taaggtggcg ttagagctga ctgacggcgg cgtcgaccat gttctggatg
    21781 ttggaggagc ggcgacgatg gtgaaatcca tcaatgcgct tcgcattgga gggacagtga
    21841 gtatggtcgg gttcttatcg ggattgacca ttccggaata cgatgtcacc ggcatcttgc
    21901 agaaagctgc aacggttcgc ggc
//
