LOCUS       NZ_JNZV01000272        18504 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces baarnensis strain NRRL B-2842 contig46.1, whole genome
            shotgun sequence.
ACCESSION   NZ_JNZV01000272
VERSION     NZ_JNZV01000272.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces baarnensis
  ORGANISM  Streptomyces baarnensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Doroghazi,J.R., Albright,J.C., Goering,A.W., Ju,K.-S., Haines,R.R.,
            Tchalukov,K.A., Labeda,D.P., Kelleher,N.L. and Metcalf,W.W.
  TITLE     A Roadmap for Natural Product Discovery Based on Large-Scale
            Genomics and Metabolomics
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18504)
  AUTHORS   Doroghazi,J.R., Ju,K.-S. and Metcalf,W.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2014) Institute for Genomic Biology, University of
            Illinois at Urbana-Champaign, 3109 IGB, MC-195, Urbana, IL 61801,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: IDBA UD v. 1.0.9
            Genome Coverage                   :: 74x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 02:19:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,395
            CDSs (total)                      :: 7,345
            Genes (coding)                    :: 7,173
            CDSs (with protein)               :: 7,173
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 55 of 173
            Pseudo Genes (incomplete)         :: 138 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 27 of 173
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:05:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18504
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JNZV01000272.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..18504
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[8619:11123](+)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 617.8; E-value:
                     1.7e-188)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 365.355"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 407.391"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      8620..11123
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 617.8; E-value:
                     1.7e-188)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 365.355"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 407.391"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     gene            complement(<1..931)
                     /locus_tag="BG84_RS0100645"
     CDS             complement(<1..931)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967309.1"
                     /locus_tag="BG84_RS0100645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation transporter"
                     /protein_id="WP_030075907.1"
                     /transl_table=11
                     /translation="MSAHSATTAGTATGSEAGTTAVELAIGGMTCASCAARIEKKLNRM
                     DGVEATVNYATEKAKVTYQGAEVSVDDLIATVEATGYTARPPAPPAPPASSGSNGTETA
                     GAAGTAGPAAEGAEDDGLTTLRQRLVTAVLLSVPVIAMAMVPALQFDYWQWLSLTLAAP
                     VVTYAAWPFHRAAWTNAKHGAATMDTLISVGTSAAFLWSLWALFFGTAGMVGMTHPFEL
                     TIARSDGAGNIYLEAAAGVTAFILAGRYFEARSKRKAGAALKALMELGAKEVTVLRDGV
                     ETTIPTAALQVGDRFLVRPGEKIATDGTV"
     source          1..18504
                     /collection_date="2010"
                     /culture_collection="NRRL:B-2842"
                     /db_xref="taxon:66872"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces baarnensis"
                     /strain="NRRL B-2842"
                     /submitter_seqid="contig46.1"
     region          1..18504
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /tool="antismash"
     cand_cluster    1..18504
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     misc_feature    956..971
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: strong, score: 31.91"
                     /tool="antismash"
     misc_feature    956..972
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: strong, score: 31.35"
                     /tool="antismash"
     misc_feature    complement(957..972)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 24.53"
                     /tool="antismash"
     misc_feature    complement(999..1015)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    complement(1173..1188)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.45"
                     /tool="antismash"
     gene            1228..1917
                     /locus_tag="BG84_RS0100650"
     CDS             1228..1917
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967308.1"
                     /locus_tag="BG84_RS0100650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="copper homeostasis protein CutC"
                     /protein_id="WP_030075909.1"
                     /transl_table=11
                     /translation="MSNRAVLEVIALDAEDAVAAQAGGADRLELVTDMAADGLTPSRET
                     FTAIRSAVDIPLRVMLRVADGFAAGDIDVLTGKAREMREAGADAFVLGFLDAEGHPDLV
                     AVERLVAELDGCPWTFHRAIDRAADRDALRKQLADLPGLDTFLTAGSAAGVDAGIPTLL
                     AEAARTGEPGYEAQVLVGGGLHLHHLPQLLAAGIDAFHIGGAARPGGWSAPVDAAAVRE
                     WREALDA"
     misc_feature    complement(1253..1268)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            complement(1962..4079)
                     /locus_tag="BG84_RS0100655"
     CDS             complement(1962..4079)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071647.1"
                     /locus_tag="BG84_RS0100655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="WP_030075911.1"
                     /transl_table=11
                     /translation="MPAHVAESDSTPDPTGPPGPVDPLAHERAHLAASRAALRGMREDV
                     QALDIRDVTANWVNAAVLQSQIDDRIKALADLSHTPLFFGRLDYLHAVGGELAEGADGE
                     RFYIGRRHVHDAAGDPMVIDWRAPVSQPYYQASRKNPQDVGLRRRFGYTAGELTAYEDE
                     HLTDPAEDGPGDEHTSRLLQAEIERPRVGPMRDIVATIQPEQDEIVRSGLGGTVCVQGG
                     PGTGKTAVGLHRVAYLLYAHRERLARTGTLVIGPNRSFLHYIEQVLPALGELEVKQATV
                     DDLVRTGVEVRGEDEAATAVVKGDARMAEVLRRAVRSHVTAPAEPVVVVRGSRRWRVPV
                     YEIQEMVDELLARDMRYGAAHEALPQRIAHAVLVRMEEAGEAPDDRVQNAVARNPAVKA
                     AVKAVWPPVDPAKLVLRLLSDAEFLAAHAEGLLSEDEQKRLLWAKPARSVKSAKWSAAD
                     AVLIDEAGDLIARTHSLGHVVLDEAQDLSPMQYRAVGRRCSTGSATVLGDLAQGTTPWS
                     TESWGEALFHLGKADAVVEELTAGFRVPREVIAYASRLLPAISPGLAAVESVRESPGSL
                     VVREVASAEELDAAVVAACEESLGHEGSIGLIAADTRIPELGAALEAAGHAYLSPGEET
                     TAASRLTLVPASLAKGLEYDYVVLDEPAAVVDGEPDERTGLRRLYVALTRAVSGLTVLH
                     AAPLPEALVQA"
     misc_feature    complement(4050..4061)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            4506..4697
                     /locus_tag="BG84_RS0100660"
     CDS             4506..4697
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765833.1"
                     /locus_tag="BG84_RS0100660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030075913.1"
                     /transl_table=11
                     /translation="MSTATLNPRTTGPAHGATAATGDHRPHRVGDAVRAVKVFVTTAFG
                     VVVLGEYAEEAGVVGRGR"
     gene            complement(4720..6363)
                     /locus_tag="BG84_RS0100665"
     CDS             complement(4720..6363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154817.1"
                     /locus_tag="BG84_RS0100665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair helicase XPB"
                     /protein_id="WP_030075915.1"
                     /transl_table=11
                     /translation="MTGPLIVQSDKTLLLEVDHDQADACRRAIAPFAELERAPEHIHTY
                     RVTPLGLWNARAAGHDAEQVVDALVEYSRYPVPHALLVDIAETMARYGRLTLSKHPVHG
                     LVLTTTDRPVLEEILRSKKVQPLVGARIDPDTVAVHPSERGQVKQTLLKLGWPAEDLAG
                     YVDGEAHPIELAEDGWALRPYQKQAVEGFWHGGSGVVVLPCGAGKTLVGAGAMAQAKAT
                     TLILVTNTVSARQWKHELVKRTSLTEDEIGEYSGTRKEIRPVTIATYQVLTTRRKGVYP
                     HLELFDSRDWGLVVYDEVHLLPAPVFKFTADLQARRRLGLTATLVREDGRESDVFSLIG
                     PKRFDAPWKEIEAQGYIAPADCVEVRVNLTDSERLAYATAETEEKYRFCATTATKRKVT
                     EALVRKHQGEQTLVIGQYIDQLDELGEHLDAPVIKGETSNAQREKLFDAFRNGEISVLV
                     VSKVANFSIDLPEATVAIQVSGTFGSRQEEAQRLGRVLRPKADGHEARFYSVVARDTID
                     QDFAAHRQRFLAEQGYAYRIVDADELLAGN"
     gene            6683..8152
                     /locus_tag="BG84_RS0100670"
     CDS             6683..8152
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 603.0; E-value: 9.7e-184)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018839763.1"
                     /locus_tag="BG84_RS0100670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_032789770.1"
                     /transl_table=11
                     /translation="MRNADVLVVGAGPTGMTLAAELRLAGARVTVLERLARRSGESRGL
                     GFTTRTMEILDQRGLLSRFGDIETSTVGHFGGLPIDFSLLDGAGQAAKSVPQSETESRL
                     EEWAVELGADIRRGDEVLAVREGGAGVEVDLRGPDGPATLTAPWLVGCDGGRSTVRGAA
                     GFDFPGTAATMEMFLADVKGVELAPRMTGQTLSGGMVMVGPLPGGVTRIVVCERGTPPR
                     RRESPPEFAEVAAAWERLTGESIAHAEPVWVSCFGDATRQVTTYRRGRVLLAGDAAHIH
                     LPAGGQGMNTGIQDAMNLGWKLGAVATGRAPESLLDSYHEERHPVGSRLLMNTRAQGLL
                     LLGGPEVQPLREVFGELVRFDEVARHLAAMVSGQEIRYDVGGGGHPLLGRRMPHLELLG
                     AEHKTSTTELLRTGRGLLLDLTGNARLRQRAVPWAARVDTVVAEPQDGPAVQGLAGTTA
                     LLIRPDGHVAWAAPGSHHDLPMALERWFGSS"
     gene            8244..8576
                     /locus_tag="BG84_RS0100675"
     CDS             8244..8576
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225: Polyketide synthesis cyclase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 187.4; E-value: 5.9e-58)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268984.1"
                     /locus_tag="BG84_RS0100675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TcmI family type II polyketide cyclase"
                     /protein_id="WP_030075919.1"
                     /transl_table=11
                     /translation="MKHSNLIVARMDERSSTEVAQLFTEFDRTDMPHRMGTLRRRLFMF
                     NGLYFHLQDFASDDGGTRIQNSRNDPRFVQISHELKPFIEPYDPETWRTPADAMATRFY
                     DWSAGE"
     gene            8620..9888
                     /locus_tag="BG84_RS0100680"
     CDS             8620..9888
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (6-395). E-value:
                     2.1e-55. Score: 180.3. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100680_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     746.3; E-value: 2e-227)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960005.1"
                     /locus_tag="BG84_RS0100680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_030075921.1"
                     /sec_met_domain="t2ks (E-value: 1.3e-232, bitscore: 762.2,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 9.3e-58, bitscore:
                     185.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERRAVITGIGVCAPGGTGADSFWELMCDGRTATRGITLFDPSPY
                     RSRVAAEIDFDPRAHGLTPQEVRRMDRAAQFGVVTAREAFADSGLDGAALDPFRTGVSL
                     GTAIGAAGGLDAEYRVVSDDGRLELVDHRYATPHLYDLFVPSSFATEVAWAVGAEGPAT
                     VVSTGCTAGIDAVGHAVEAIRDGSADVMVTGAVDAPITPLTMAAFDAIRATTSLNDEAD
                     TASRPFDASRKGFVLGEGAAVFVLEEAEHARRRGAYVYAEIAGYASRGNAFHMTGLRSD
                     GAELAAAIRAALDEARLDASAVDYVNAHGSGTRQNDRHETVALKSALGQHAHRVPVSAI
                     KSMVGHSLGAIGSIEIAACALAMRHHVIPPTANLHTPDPECDLDYVPLTARAQRTDAVL
                     TIGSGFGGFQSAMVLARPDRSAA"
     aSDomain        8638..9804
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100680_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.10E-55"
                     /label="BG84_RS0100680_PKS_KS.1"
                     /locus_tag="BG84_RS0100680"
                     /protein_end="395"
                     /protein_start="6"
                     /score="180.3"
                     /tool="antismash"
                     /translation="ITGIGVCAPGGTGADSFWELMCDGRTATRGITLFDPSPYRSRVAA
                     EIDFDPRAHGLTPQEVRRMDRAAQFGVVTAREAFADSGLDGAALDPFRTGVSLGTAIGA
                     AGGLDAEYRVVSDDGRLELVDHRYATPHLYDLFVPSSFATEVAWAVGAEGPATVVSTGC
                     TAGIDAVGHAVEAIRDGSADVMVTGAVDAPITPLTMAAFDAIRATTSLNDEADTASRPF
                     DASRKGFVLGEGAAVFVLEEAEHARRRGAYVYAEIAGYASRGNAFHMTGLRSDGAELAA
                     AIRAALDEARLDASAVDYVNAHGSGTRQNDRHETVALKSALGQHAHRVPVSAIKSMVGH
                     SLGAIGSIEIAACALAMRHHVIPPTANLHTPDPECDLDYVPLTARAQRT"
     gene            9933..11123
                     /locus_tag="BG84_RS0100685"
     CDS             9933..11123
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (55-357). E-value:
                     4.4e-23. Score: 73.8. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100685_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 617.8; E-value: 1.7e-188)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037162.1"
                     /locus_tag="BG84_RS0100685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketosynthase chain-length factor"
                     /protein_id="WP_030075923.1"
                     /sec_met_domain="t2clf (E-value: 3.8e-185, bitscore: 605.4,
                     seeds: 26, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.5e-38, bitscore:
                     122.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLATPHGVDVEDFWAATRVGKNAIGPVTRFDASGYPARLAGEIR
                     GFSAADHLPGRLVAQTDRVTQLALVAADRAFRDAGVAPGDLPADGMGVVTAAGSGGFEF
                     GERELRKLWSLGANHVSAYQSFAWFPTANTGQIAIRSDSRGPNGVVVGDQAGGLDALGQ
                     ARRLIRRGTGLVAAGGFEASLTPLGWTARLSTGLMSTSDDPDRAYLPFHPAARGYVPGE
                     GGALLILEDERSALARGAATAHAELAGYSATLDPRPGSGREPGLRRAIELALADAGVAP
                     AEVDVVFADAAGSPEPDAVEVAAVASVFGPRAVPVTAPKTMIGRLQAGGAPVDVVTAVL
                     AIREGLIPPTADAESATARELDLVVGRPRTASVGTALVLARGHGGFNSAVVLRAVD"
     aSDomain        10098..11003
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100685_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.40E-23"
                     /label="BG84_RS0100685_PKS_KS.1"
                     /locus_tag="BG84_RS0100685"
                     /protein_end="357"
                     /protein_start="55"
                     /score="73.8"
                     /tool="antismash"
                     /translation="RLVAQTDRVTQLALVAADRAFRDAGVAPGDLPADGMGVVTAAGSG
                     GFEFGERELRKLWSLGANHVSAYQSFAWFPTANTGQIAIRSDSRGPNGVVVGDQAGGLD
                     ALGQARRLIRRGTGLVAAGGFEASLTPLGWTARLSTGLMSTSDDPDRAYLPFHPAARGY
                     VPGEGGALLILEDERSALARGAATAHAELAGYSATLDPRPGSGREPGLRRAIELALADA
                     GVAPAEVDVVFADAAGSPEPDAVEVAAVASVFGPRAVPVTAPKTMIGRLQAGGAPVDVV
                     TAVLAIREGLIPPTADAESAT"
     misc_feature    11233..11246
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.17"
                     /tool="antismash"
     gene            11239..11508
                     /locus_tag="BG84_RS0100690"
     CDS             11239..11508
                     /NRPS_PKS="Domain: ACP (12-81). E-value: 3.3e-17. Score:
                     54.6. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100690_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 133.7; E-value: 4.2e-42)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037163.1"
                     /locus_tag="BG84_RS0100690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_030075927.1"
                     /sec_met_domain="PP-binding (E-value: 7.9e-13, bitscore:
                     39.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQEFTLEDLKRILLEGAGADEGVDLDGDILDTDFEELGYESLA
                     LLETGGRIEREYGITLDDDVLADSRTPRSLIAAINAAFQGLVEA"
     aSDomain        11275..11481
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100690_ACP.1"
                     /evalue="3.30E-17"
                     /label="BG84_RS0100690_ACP.1"
                     /locus_tag="BG84_RS0100690"
                     /protein_end="81"
                     /protein_start="12"
                     /score="54.6"
                     /tool="antismash"
                     /translation="RILLEGAGADEGVDLDGDILDTDFEELGYESLALLETGGRIEREY
                     GITLDDDVLADSRTPRSLIAAINA"
     gene            11628..12413
                     /gene="fabG"
                     /locus_tag="BG84_RS0100695"
     CDS             11628..12413
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-119). E-value: 7.4e-12. Score:
                     37.5. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100695_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 478.8; E-value: 8.8e-147)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050069.1"
                     /locus_tag="BG84_RS0100695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_030075930.1"
                     /sec_met_domain="adh_short (E-value: 2.3e-37, bitscore:
                     118.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQDKRVAVVTGATSGIGLSVARLLASQGHRVFIGARSAENVAA
                     TVKELVAEGLDVDGAVVDVRSDADVEAWIQAAVDRFGTVDVVVNNAGRSGGGVTADIDP
                     ELWHDVIDTNLNSVFRVTRSALNTGGLRSKSRGRIINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRQGYAAAYDATEDAILEKFQAKIP
                     LGRYSTPDEVAGLVGYLASDTAASITSQALNVCGGLGNF"
     aSDomain        11649..11984
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100695_PKS_KR.1"
                     /evalue="7.40E-12"
                     /label="BG84_RS0100695_PKS_KR.1"
                     /locus_tag="BG84_RS0100695"
                     /protein_end="119"
                     /protein_start="7"
                     /score="37.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGATSGIGLSVARLLASQGHRVFIGARSAENVAATVKELVA
                     EGLDVDGAVVDVRSDADVEAWIQAAVDRFGTVDVVVNNAGRSGGGVTADIDPELWHDVI
                     DTNLNSVF"
     CDS_motif       11655..11723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BG84_RS0100695_0001"
                     /evalue="2.00E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="BG84_RS0100695"
                     /protein_end="32"
                     /protein_start="9"
                     /score="23.7"
                     /tool="antismash"
                     /translation="VVTGATSGIGLSVARLLASQGHR"
     gene            12478..13437
                     /locus_tag="BG84_RS0100700"
     CDS             12478..13437
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-149). E-value:
                     1.3e-13. Score: 43.5. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100700_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (158-311). E-value:
                     2.3e-10. Score: 33.0. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100700_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 510.6; E-value: 2.7e-156)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007269009.1"
                     /locus_tag="BG84_RS0100700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aromatase/cyclase"
                     /protein_id="WP_030075932.1"
                     /transl_table=11
                     /translation="MSQPGLREVEHEITVSAPAAAVYRLIAEVRNWPRIFPPTIYVDHV
                     EENGDEERIRIWATANDEAKNWTSRRTLDPEGLRITFRQEVPAPPVAAMGGAWIIEPLG
                     DAESRIRLLHDYRAVDDDPAHLEWIDQAVDRNSRSELAALKGNVEKAHAEEGLTFSFED
                     TVRVDGAAKDVYDFVNEADLWHERLPHVATVRLREDTPGLQELEMDTRAKDGSTHTTKS
                     YRVTFPHHRIAYKQTTLPALMTLHTGYWTFAEDDRGVLASSQHTVTINTANIARVLGPE
                     ATVEDAKAYVHTALSTNSTATLNHAKRFAEERAAGRRG"
     aSDomain        12499..12924
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100700_Polyketide_cyc2.1
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.30E-13"
                     /label="BG84_RS0100700_Polyketide_cyc2.1"
                     /locus_tag="BG84_RS0100700"
                     /protein_end="149"
                     /protein_start="7"
                     /score="43.5"
                     /tool="antismash"
                     /translation="EVEHEITVSAPAAAVYRLIAEVRNWPRIFPPTIYVDHVEENGDEE
                     RIRIWATANDEAKNWTSRRTLDPEGLRITFRQEVPAPPVAAMGGAWIIEPLGDAESRIR
                     LLHDYRAVDDDPAHLEWIDQAVDRNSRSELAALKGNVE"
     aSModule        12499..13410
                     /domains="nrpspksdomains_BG84_RS0100700_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_BG84_RS0100700_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="BG84_RS0100700"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        12952..13410
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100700_Polyketide_cyc2.2
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.30E-10"
                     /label="BG84_RS0100700_Polyketide_cyc2.2"
                     /locus_tag="BG84_RS0100700"
                     /protein_end="311"
                     /protein_start="158"
                     /score="33.0"
                     /tool="antismash"
                     /translation="FSFEDTVRVDGAAKDVYDFVNEADLWHERLPHVATVRLREDTPGL
                     QELEMDTRAKDGSTHTTKSYRVTFPHHRIAYKQTTLPALMTLHTGYWTFAEDDRGVLAS
                     SQHTVTINTANIARVLGPEATVEDAKAYVHTALSTNSTATLNHAKRFAE"
     gene            13440..15452
                     /locus_tag="BG84_RS0100705"
     CDS             13440..15452
                     /NRPS_PKS="Domain: PKS_KR (424-603). E-value: 1.1e-06.
                     Score: 20.6. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100705_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 476.4; E-value: 2.4e-145)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610258.1"
                     /locus_tag="BG84_RS0100705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_050495427.1"
                     /transl_table=11
                     /translation="MPEDDDARIVVVGAGPVGLLLAGLLRRSGADVVVLEQLTAPTTES
                     RASTLHARTMEILDGCGVRDWLGAVEREPRGHFGGIGLDLTLPVPHPGQWKVPQTRLEE
                     VLARWARELGVRIRRGHEVIGLTRAADHVTVDVRRHGPGRAVRGTVRARWLVGCDGERG
                     AVGRLGGFTFTGGPARRELLRADVAGLTIAARRFERAERGLLVAAPLPGGVTRVMVHER
                     GAEPLPGPPRFADLVAAWRRVAGEDIAGGVPLWVNSFDDACRQADRYRIGRLLLAGDAA
                     HRQLPIGGQSLNLGLQDAWDLGRKLAAVACGRAPAALLDSYHDERHRAGRQVQDDVRAQ
                     ALLLFGGPEVDAVRQVLAELTGHERVRVHLARRIGGWPDRPDGRPATAGTGTHDHDHDH
                     GDDHGAGDGDVRGRRGEAMGRLTGRTALVTGSSRGMGRATAIRLAADGALVAVHYAENK
                     DAAAEVVAAIESDGGRAFAVGARLGVPGDVEELFGALEPALLDRTGSTDLNILVNNAGV
                     MSGTEPLSRTTEGFDRLFAVNARAPYFLIRRALENMPDGGRIVNISSGLTRCANPDEIV
                     YAMSKGALEQLALHFAKLLGPRGITVNSVAPGITRNDQPVFRIAEAVDQMAARSVFHRI
                     GEPEDIADVVAFLATDEARWITGSFVDATGGTLVG"
     aSDomain        14712..15248
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100705_PKS_KR.1"
                     /evalue="1.10E-06"
                     /label="BG84_RS0100705_PKS_KR.1"
                     /locus_tag="BG84_RS0100705"
                     /protein_end="603"
                     /protein_start="424"
                     /score="20.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSSRGMGRATAIRLAADGALVAVHYAENKDAAAEVVAAIE
                     SDGGRAFAVGARLGVPGDVEELFGALEPALLDRTGSTDLNILVNNAGVMSGTEPLSRTT
                     EGFDRLFAVNARAPYFLIRRALENMPDGGRIVNISSGLTRCANPDEIVYAMSKGALEQL
                     ALHFAKLLGPRGITVN"
     gene            15452..16762
                     /locus_tag="BG84_RS0100710"
     CDS             15452..16762
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511398.1"
                     /locus_tag="BG84_RS0100710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_050495428.1"
                     /transl_table=11
                     /translation="MGPGPVGPPAVRRTPWPLVCVLAATMLVDALEVSAAVVSAPVVGD
                     ALDLAPAVLFWLVGGFAAGFAAVLPWAAALGRRFGRRRVQLVALAVFALASAASAAADS
                     GGWLILGRAVKGGCAALTAPTGLAIILAAVPDGPDRRRAVSGYALCGTAGFCGGLLLAG
                     LLTGVDWRLVPALPVPAALLLLVLAARLVPRDPPVRRRARPRVRPGRPSAGPRVLWRCR
                     PLRRAALTAAAFNGAYVVLLLVTAWQLHHRGGWTPLRTALVFLPAAAPAALTALWSARI
                     AVRLGPDRSAAAGAVLAVVGCLLVPRDAGAAGSGAAGLLPATAVLGLAFLLAFTALHLQ
                     AVDAVPEELRPAATAFYQTWVQAGPVLLTAPAAALVTAGADIGPALWLVTAVAAAGALV
                     AVTGLLPSGPPGPPSTPRPRSSHDDPSTLPYVRDGGR"
     gene            16716..17099
                     /locus_tag="BG84_RS0100715"
     CDS             16716..17099
                     /NRPS_PKS="Domain: PKS_PP (27-110). E-value: 9.5e-12.
                     Score: 37.1. Matches aSDomain:
                     nrpspksdomains_BG84_RS0100715_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="BG84_RS0100715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_030075938.1"
                     /sec_met_domain="PP-binding (E-value: 5e-08, bitscore:
                     23.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLQLSRTYETEDGDTITMTVPDIAVLHSVDLAERTAILERYVR
                     EQLGRVLAVHPSRVDTTGRPMGCLGIGSISGMELQYRMEDALGVELHLQRLLLANSAQE
                     LIDCLAWQFGPEGAGKYGTAVAS"
     aSDomain        16797..17045
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS0100715_PKS_PP.1"
                     /evalue="9.50E-12"
                     /label="BG84_RS0100715_PKS_PP.1"
                     /locus_tag="BG84_RS0100715"
                     /protein_end="110"
                     /protein_start="27"
                     /score="37.1"
                     /tool="antismash"
                     /translation="LHSVDLAERTAILERYVREQLGRVLAVHPSRVDTTGRPMGCLGIG
                     SISGMELQYRMEDALGVELHLQRLLLANSAQELIDCLA"
     gene            17096..17893
                     /locus_tag="BG84_RS01000000137120"
     CDS             17096..17893
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (140-204). E-value: 4.8e-09. Score:
                     28.1. Matches aSDomain:
                     nrpspksdomains_BG84_RS01000000137120_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268991.1"
                     /locus_tag="BG84_RS01000000137120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_030075940.1"
                     /transl_table=11
                     /translation="MNGSILLPATATEIRQPGPDEPSAFTVAADRIDLWLIHPPEGDAA
                     GSLARAELDERERARADAFVRPSDGLLYAAAHVALRRLIAAYTAGRPQDVRFMREACPG
                     CGESHGRPAVAPPPPPLHFSLSHSAGVALVGVADRPIGVDVERLPGAETVDICSRSLHP
                     EEQAELNEVPEGEARRKLFGRIWTRKEAYLKGLGTGLSRSPAEDYLGADRDRHPGDWTM
                     VGIPCVATHAASAAVRGTPPAVAEVRTLPGAWLTDGRPPAAPA"
     aSDomain        17516..17707
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BG84_RS01000000137120_ACPS.1"
                     /evalue="4.80E-09"
                     /label="BG84_RS01000000137120_ACPS.1"
                     /locus_tag="BG84_RS01000000137120"
                     /protein_end="204"
                     /protein_start="140"
                     /score="28.1"
                     /tool="antismash"
                     /translation="IGVDVERLPGAETVDICSRSLHPEEQAELNEVPEGEARRKLFGRI
                     WTRKEAYLKGLGTGLSRSP"
     gene            17956..>18504
                     /locus_tag="BG84_RS0100725"
     CDS             17956..>18504
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562055.1"
                     /locus_tag="BG84_RS0100725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_030075942.1"
                     /transl_table=11
                     /translation="MPTAQDRAGTADTVHGRVDALLAMKDSARAGDAEATRRQHAKGKL
                     TAYERIGLLLDKGSFTEVEGLRRHRATGFGLEAKKPAGDGVVTGWGTVHGRSVFVYAHD
                     FRAFGGALGEAHAAKIHKVMDLAEAAGAPLVSLNDGAGARIQEGVTALAGYGGIFRRNT
                     RASGVIPQISVMLGPCAGGA"
ORIGIN
        1 ccacggtccc gtccgtcgcg atcttctccc cggggcggac caggaaacgg tccccgacct
       61 gcaacgcggc ggtcgggatc gtcgtctcga caccgtcgcg caggaccgtg acctccttgg
      121 cccccagctc catcagcgcc ttcagcgccg ccccggcctt ccgcttcgag cgtgcctcga
      181 agtagcgccc ggcgaggatg aacgccgtca ccccggccgc ggcctccagg tagatgttcc
      241 cggcgccgtc gctgcgggcg atggtcagct cgaaggggtg cgtcatcccg accatgcccg
      301 cggtcccgaa gaacagcgcc cacagcgacc acaggaacgc ggccgacgtg ccgacggaga
      361 tcagcgtgtc catcgtcgcc gcaccgtgct tcgcgttggt ccaggcggcg cggtggaacg
      421 gccaggcggc gtaggtgacg accggtgcgg ccagggtcag cgagagccac tgccagtagt
      481 cgaactggag cgccggaacc atcgccatcg cgatcaccgg gacggacagg aggacggcgg
      541 tgaccaggcg ctggcgcagg gtggtgagcc cgtcgtcctc cgcgccctcc gccgccggac
      601 ccgccgtacc cgccgcgccc gccgtctccg taccgttgct cccggaggag gcgggcggtg
      661 cgggtggcgc gggcggccgg gcggtgtagc cggtggcctc gacggtcgcg atcaggtcgt
      721 cgacggacac ctcggcgccc tggtaggtga ccttcgcctt ctcggtggcg tagttcacgg
      781 tggcctcgac gccgtccatc cggttgagct tcttctcgat acgggccgca cacgaggcgc
      841 aggtcatccc gccgatcgcg agctcgaccg cggtggtgcc ggcctcggag ccggtggcgg
      901 taccggcggt ggtggcggag tgcgcggaca cggggtcctc cctggagccg tccggatacc
      961 cctagggggt atctccttct ctctccatgt ataccccccg cccctatgaa gtgcaaggtg
     1021 tgacgggagg ggttgtggag ggggcggcgg cgggccgccg aggggtttcc ggcggtgcgg
     1081 gtcactcgtc tgcggggtcg gctcgcgtgc cgccgcgtgc gtgcgctgag atagagggct
     1141 gggctgtccg tctaccgacc cgtaggctgg ccattggact agacctatag ctgtgtatcg
     1201 agctgtgtat cggaggaatg gggacccatg agcaaccgtg cagtcctgga ggtgatcgct
     1261 ctcgacgcgg aggacgcggt cgctgcccag gccggtggtg cagaccgcct cgaactggtc
     1321 accgacatgg ccgccgacgg tctgacaccg tcacgggaga ccttcacggc gatcaggtcc
     1381 gcggtggaca tcccgctgcg cgtgatgctc agggtggcgg acggcttcgc cgccggtgac
     1441 atcgacgtac tgaccggcaa ggcccgcgag atgcgggagg cgggggccga cgcgttcgtg
     1501 ctcggcttcc tcgacgcgga gggccacccc gacctcgtcg ccgtcgaacg gctcgtcgcc
     1561 gagctggacg gctgcccgtg gacgttccac cgggcgatcg accgggccgc cgaccgcgac
     1621 gccctgcgca agcagctcgc ggacctgccc ggcctcgaca cgttcctcac ggcgggttcg
     1681 gcggccggag tggacgcggg catcccgacg ctcctggccg aggcggcccg taccggcgag
     1741 cccggatacg aggcacaggt cctggtcggc ggcggcctcc acctgcacca cctgccacag
     1801 ctgctggccg ccgggatcga cgccttccac atcggcggcg cggcccggcc cgggggctgg
     1861 tcggcgccgg tggacgcggc agcggtacgg gagtggcgcg aggcgctgga cgcctgaggt
     1921 ccgaccgggt gcgggaccgg gcagtcccgc acccggaggg cctacgcctg aaccagcgcc
     1981 tccggcaacg gggccgcgtg cagcacggtc agccccgaca ccgcacgggt cagcgccacg
     2041 tacagccgcc gcagcccggt ccgctcgtcc ggttcgccgt cgaccacggc ggccggttcg
     2101 tccagcacca cgtagtcgta ctccaggccc ttggccagcg acgcgggcac cagcgtcagc
     2161 cgcgacgcgg cggtggtctc ctcgccgggc gagagatacg cgtggcccgc cgcctccaga
     2221 gccgcgccca gctccgggat ccgggtgtcg gcggcgatca gcccgatcga cccctcgtgg
     2281 ccgagcgact cctcgcaggc ggcgacgacg gccgcgtcca gctcctcggc cgacgccacc
     2341 tcccgtacga ccagggaacc cggcgactca cgcaccgact ccaccgcggc cagacccggc
     2401 gagatcgcgg gcagcagccg ggaggcgtac gcgatgacct cgcgcggcac acggaaaccg
     2461 gccgtcagct cctccaccac cgcgtccgcc ttgcccaggt ggaacagcgc ctcgccccag
     2521 ctctccgtgg accacggcgt cgtcccctgc gcgaggtcgc cgaggacggt ggcggacccg
     2581 gtcgagcagc gccgccccac cgcccggtac tgcatggggg acaggtcctg cgcctcgtcg
     2641 agcacgacat ggccgagcga gtgcgtccgg gcgatcagat cgcccgcctc gtcgatcagc
     2701 acggcgtccg ccgccgacca cttcgcggac ttcacactgc gggcgggctt cgcccacagc
     2761 agccgcttct gctcgtcctc gctcagcagg ccttccgcgt gcgcggccag gaactccgcg
     2821 tcggagagca gccgcagcac cagcttcgcc gggtccacgg ggggccagac cgccttgacg
     2881 gccgccttca cggcggggtt gcgggccacg gcgttctgca cccggtcgtc gggcgcctcc
     2941 ccggcctcct ccatccgtac gaggacggcg tgcgcgatcc gctgcggcag cgcctcgtgc
     3001 gccgccccgt accgcatgtc gcgggccagc agctcgtcga ccatctcctg gatctcgtac
     3061 accggcaccc gccagcgccg ggagccgcgc accacgacga cgggctcggc gggggcggtc
     3121 acatgggagc ggacggcccg ccgcagcacc tcggccatcc gggcgtcgcc cttgacgacg
     3181 gcggtggccg cctcgtcctc gccccgcacc tcgacaccgg tgcgcaccag gtcgtcgacg
     3241 gtggcctgct tcacctccag ctcgccgagc gcgggcagga cctgctcgat gtagtgcagg
     3301 aaggaccggt tcggcccgat gacgagggtg ccggtgcggg cgagccgctc gcggtgcgcg
     3361 tagagcaggt acgccacccg gtgcaggccg acggcggtct tcccggtgcc gggcccgccc
     3421 tgcacgcaga cggtgccgcc gaggccgctg cggacgatct cgtcctgctc gggctggatg
     3481 gtggcgacga tgtcgcgcat cgggccgacg cgcggccgtt cgatctccgc ctggaggagg
     3541 cggctggtgt gctcgtcccc ggggccgtcc tcggcggggt cggtgaggtg ctcgtcctcg
     3601 tacgcggtca gctcgccggc cgtgtagccg aaccggcggc ggagcccgac gtcctggggg
     3661 ttcttccggg acgcctggta gtacggctgg gagaccggcg cacgccagtc gatgaccatc
     3721 gggtcgccgg cggcgtcgtg gacgtggcgg cggccgatgt agaaccgctc gccgtccgcg
     3781 ccttcggcca gttcgccgcc gacggcgtgc agatagtcga ggcggccgaa gaacagcggg
     3841 gtgtgcgaga gatcggcgag cgccttgatg cggtcgtcga tctgggactg gagcacggcg
     3901 gcgttgaccc agttcgcggt gacatcgcgg atgtcgaggg cctggacgtc ctcgcgcatc
     3961 ccgcgcagcg cggcgcggga cgcggccaga tgggcgcgtt cgtgcgccag cgggtcgacg
     4021 gggcccgggg gaccggtcgg gtcgggggtg gaatcgcttt ctgctacgtg cgcgggcacg
     4081 gtgatgcctc cggctcttca acacaggacg gcggaccgcg cgccggtacc ggccggggcc
     4141 ggggcggggc ggtccgctcg gaaggtcgct tcgcgtgggt gccgtccggt ttccgtccgg
     4201 gcggcggcgc tcccccggct gccggcagcg aaaaggccgg taccacggtt cgggaggcgg
     4261 gcagaccggc gattgtagcc acagggcggg gcgcggtcga aacgctttac ggggttccgc
     4321 cgccgtacgg gcccggccgg cgacgggctg cgccgcctgt gcgggctcca cctgaggggg
     4381 cggtccaagg ggtacccgta ggggacgccg ggcctcggca tggcaccgca gacctacgcg
     4441 cccgctcacc cggttccgtc tgcgggccga cgcgcccgaa cgggtgacgg gagcaccatg
     4501 gatacatgag cacagccacc ctgaatcccc gcacgaccgg ccccgcgcac ggcgcgaccg
     4561 cggcgaccgg tgaccaccga ccccaccgcg tcggcgacgc ggtgcgcgcc gtgaaggtgt
     4621 tcgtgaccac ggcgttcggc gtcgtcgtcc tgggggagta cgcggaagag gcgggcgtcg
     4681 tcggccgcgg ccgctgaacg cccgcccctt ccggaggcgt cagttgcccg cgagcagctc
     4741 gtccgcgtcg acgatgcggt acgcgtaccc ctgctcggcc aggaaccgct ggcggtgcgc
     4801 cgcgaagtcc tggtcgatgg tgtcgcgggc gacgaccgag tagaaccggg cctcgtgccc
     4861 gtcggccttc ggccgcagga cgcggcccag ccgctgcgcc tcctcctggc gtgacccgaa
     4921 ggtgccggag acctggatgg cgacagtggc ctccggcagg tcgatggaga agttggcgac
     4981 cttggagacc acgaggacgc tgatctcgcc gttccggaac gcgtcgaaga gcttctcgcg
     5041 ctgggcgttg ctggtctcgc ccttgatgac gggcgcgtcc agatgctcgc ccagctcgtc
     5101 gagctggtcg atgtactgcc cgatgacgag ggtctgctcg ccctggtgct tgcgcaccag
     5161 cgcctcggtc accttccgct tggtggccgt ggtcgcgcag aaccggtact tctcctccgt
     5221 ctcggcggtc gcgtacgcga gccgctcgga gtcggtgagg ttgacgcgga cctccacgca
     5281 gtcggcgggc gcgatgtagc cctgcgcctc gatctccttc cacggagcgt cgaaccgctt
     5341 gggcccgatg agcgagaaga cgtcggactc ccgcccgtcc tcccggacca gcgtcgcggt
     5401 gagccccagc cgccgccggg cctggaggtc ggcggtgaac ttgaagacgg gcgcgggcag
     5461 cagatgtacc tcgtcgtaga cgaccaggcc ccagtcacgg gagtcgaaga gctccaggtg
     5521 cgggtagacg cccttccgcc gggtggtcag cacctggtag gtggcgatgg tgaccggccg
     5581 gatctccttg cgcgtcccgc tgtactcgcc gatctcgtcc tcggtcagcg aggtccgctt
     5641 caccagctcg tgcttccact gccgggcgga gacggtgttg gtgacgagga tcagggtggt
     5701 ggccttggcc tgggccatgg caccggcccc gacgagcgtc ttcccggccc cgcagggcag
     5761 caccacgacg cccgacccac cgtgccagaa gccctccacg gcctgcttct ggtacggccg
     5821 cagcgcccag ccgtcctcgg ccagctcgat cggatgggcc tcgccgtcga cgtaaccggc
     5881 aaggtcctcc gcgggccacc ccagcttgag cagggtctgc ttgacctgcc cgcgctcgga
     5941 ggggtgcacg gccacggtgt ccgggtcgat gcgggccccg accagcggct ggaccttctt
     6001 cgaccggagg atctcctcca gcacgggccg gtcggtggtg gtgagcacga gcccgtgcac
     6061 cgggtgcttg gacagggtga gccgcccgta ccgcgccatc gtctcggcga tgtcgaccag
     6121 gagcgcgtgc ggcacggggt agcgggagta ctcgaccagg gcgtcgacga cctgctcggc
     6181 gtcgtgcccg gcggcgcggg cgttccacag cccgagcggg gtgacccggt acgtgtggat
     6241 gtgctcgggc gcgcgctcca gctccgcgaa cggcgcgatg gcacgacggc aggcgtccgc
     6301 ctggtcgtgg tcgacctcga ggagcagcgt cttgtcgctc tggacgatga ggggtccggt
     6361 cacgcgcttc ggccctttct gcggggtacg gccacggctg cggccaaacg tccagtgtgc
     6421 cgcatcgcgg agcggggcgg ggtgggcctg cgcgggggag ggcacgggag ccgagggcgg
     6481 ggccgtccgg cgggcccgtg ccgccgcgcc cgcggctccc gacttcgcac cgccttgacg
     6541 tacaccttgc gtgccccgga cgcaccggac acgcgcttac ggaacctgac ggaagccttt
     6601 aaccgccgct gttgaagcgg cggacgcggc cgaagaacct tgagttcagg atccggtgcg
     6661 gtgtgttcgg gaggagagag ccgtgaggaa cgccgatgtg ctcgtcgtgg gcgccgggcc
     6721 caccggaatg accctggcgg ccgagctccg gctcgccggc gcacgggtga ccgtgctgga
     6781 acggctggcg cgacgcagcg gcgaatcccg ggggctgggc ttcaccaccc gcacgatgga
     6841 gatcctcgac cagcggggcc tgctgtcgcg tttcggcgac atcgagacca gcaccgtcgg
     6901 acacttcggc ggccttccga tcgacttctc gctcctggac ggtgcgggcc aggcggccaa
     6961 gtcggtgccg cagtccgaga ccgagagccg cctggaggag tgggccgtcg agctcggcgc
     7021 cgacatccgg cgcggtgacg aggtgctcgc cgtgcgtgag ggcggcgccg gtgtcgaggt
     7081 ggacctgcgc ggtccggacg gaccggcgac gctgaccgcg ccgtggctgg tcggatgcga
     7141 cggcggacgc agcacggtcc gcggcgcggc cggcttcgac ttccccggca ccgccgcgac
     7201 catggagatg ttcctcgccg acgtcaaggg cgtcgagctg gcgccccgga tgacggggca
     7261 gacgctgtcc ggcggcatgg tgatggtggg ccccctgccg ggcggcgtca ccaggatcgt
     7321 ggtgtgcgag cgcggcaccc cgccgcgcag acgtgagtcg ccgccggagt tcgcggaggt
     7381 cgcggcggcc tgggagcggc tgaccggaga gtcgatcgcg cacgccgaac cggtgtgggt
     7441 gagctgcttc ggcgacgcca cgcgccaggt caccacgtac cggcgcggcc gggtgctgct
     7501 ggccggcgac gccgcgcaca tccatctgcc ggccggcggc cagggcatga acaccggcat
     7561 ccaggacgcc atgaacctgg gctggaagct cggcgcggtc gcgaccggcc gggcgccgga
     7621 gagcctgctc gactcgtacc acgaggaacg ccacccggtc ggcagccgcc tcctgatgaa
     7681 cacgcgggcc cagggcctgc tgctcctcgg cggacccgaa gtgcagccgc tgcgcgaggt
     7741 gttcggcgaa ctcgtccgct tcgacgaggt cgcgcggcac ctggccgcca tggtgagcgg
     7801 ccaggagatc cgttacgacg tcggcggcgg cggccatccg ctgctgggcc ggcgcatgcc
     7861 gcacctggaa ctgctcggcg ccgagcacaa gacctccacc accgaactgc tccgcaccgg
     7921 ccgcggactc ctgctcgacc tgaccggcaa cgcccggctg cggcagcggg ccgtgccgtg
     7981 ggcggcccgg gtggacaccg tggtcgccga gccgcaggac gggccggcgg tccagggcct
     8041 cgccggcacc acggcgctgc tgatccggcc ggacgggcat gtggcctggg ccgctccggg
     8101 cagtcaccac gacctgccga tggcgctcga acgctggttc ggctcttcct gagcgcgcgg
     8161 acagccgccc cttccgaggg cgtgcgtgcg atccaccacc ggtacgcgac cacgcgtaca
     8221 ccgacggaga gatgagagac gtcatgaagc acagcaacct gatcgtcgcc aggatggacg
     8281 agcggtcgag caccgaagtg gcccagctct tcaccgagtt cgaccggacg gacatgccgc
     8341 accggatggg cacgctgcgc cggcggctgt tcatgttcaa cggcctgtac ttccacctcc
     8401 aggacttcgc gtccgacgac ggcggcaccc ggatccagaa ctcccgcaac gatccgcgct
     8461 tcgtgcagat cagccatgaa ctcaagccgt tcatcgagcc gtacgacccg gagacctggc
     8521 ggacgccggc cgacgcgatg gccacgcgct tctacgactg gtcggcaggc gagtgacctc
     8581 ggcacggcac cgcaccggac cggaaggagg acggcagcag tggaacgccg ggcagtgatc
     8641 acggggatcg gtgtgtgcgc accgggcgga accggtgcgg acagcttctg ggagctgatg
     8701 tgcgacggcc ggacggccac ccgcggcatc accctcttcg acccgtctcc gtaccgctcc
     8761 agggtcgccg ccgagatcga cttcgacccg cgggcgcacg gactgacgcc gcaggaggtc
     8821 cggcggatgg accgggccgc gcagttcggc gtggtgacgg cacgggaggc cttcgccgac
     8881 agcggtctcg acggcgccgc gctcgatccg ttccgtacgg gagtcagcct cggcaccgcg
     8941 atcggcgcgg ccggcggcct ggacgcggag taccgcgtgg tcagcgacga cggccggctg
     9001 gagctggtcg accaccggta cgcgaccccg catctgtacg acctgttcgt gccgagctcc
     9061 ttcgcgaccg aagtggcctg ggccgtcggc gcggaaggac cggcgacggt ggtgtccacc
     9121 ggctgcaccg ccgggatcga cgcggtgggc cacgcggtgg aggcgatccg cgacggcagc
     9181 gccgatgtga tggtcaccgg cgcggtggac gcgccgatca ccccgctcac gatggcggcc
     9241 ttcgacgcga tccgcgccac cacgtccctc aacgacgagg cggacaccgc ctcccgcccc
     9301 ttcgacgcgt cacgcaaggg cttcgtcctc ggtgaggggg cggcggtgtt cgtcctggag
     9361 gaggcggagc acgcacggcg cagaggcgcg tacgtgtacg cggagatcgc cggatacgcc
     9421 tcgcgcggca acgccttcca catgaccgga ctgcggtccg acggagcgga gctggccgcc
     9481 gcgatccggg cggcgctgga cgaggcccgg ctcgacgcgt cggcggtgga ctacgtcaac
     9541 gcgcacggct ccggcacccg ccagaacgac cggcacgaga cggtcgcgct caagtcggct
     9601 ctgggacagc acgcccaccg ggtgccggtc agcgcgatca agtcgatggt cgggcactcg
     9661 ctcggggcga tcggctccat cgagatcgcc gcctgcgcac tggccatgcg gcaccacgtc
     9721 atccctccga ccgccaatct gcacaccccg gatcccgagt gcgatctcga ctatgtcccg
     9781 ctgacggccc gcgcgcagcg caccgatgcc gtcctcacca tcggcagcgg attcggcggc
     9841 ttccagagcg cgatggtgct ggcccgtccc gacaggagcg ccgcgtgagc gccccgggcg
     9901 gcggcgaccg cggccgcacg ttgatcaccg gcatgggact ggccacaccg cacggcgtcg
     9961 acgtggagga tttctgggcg gcgacacggg tcggcaagaa cgccatcgga ccggtcaccc
    10021 ggttcgacgc gtccggctac ccggcgcggc tggcgggaga gatccgcgga ttctcggccg
    10081 cggaccatct gccgggccgg ctggtggcgc agaccgaccg ggtgacccaa ctggccctgg
    10141 tcgccgcgga ccgcgcgttc cgggacgccg gggtggctcc gggcgacctt cccgcggacg
    10201 ggatgggcgt ggtcacggcg gccggttccg gcggtttcga gttcggcgag cgggagttgc
    10261 gcaagctctg gagcctcggc gcgaaccacg tgagcgccta ccagtcgttc gcctggttcc
    10321 cgaccgccaa caccggccag atcgcgatcc gcagcgacag ccgcggaccg aacggcgtgg
    10381 tcgtcggcga ccaggccggc ggcctcgacg cgctcggaca ggcccggcgg ctcatccgcc
    10441 gcggcaccgg actggtcgcc gcgggcggct tcgaggcgtc gctgacaccg ctcggctgga
    10501 cggcacggct gtcgaccgga ctgatgtcga ccagcgacga tcccgaccgc gcctatctgc
    10561 cgttccatcc ggcggcgcgc ggctacgttc ccggcgaggg cggcgcactg ctgatcctgg
    10621 aggacgagcg cagcgccctg gcccgcggag cggccaccgc ccacgccgaa ctggccgggt
    10681 acagcgcgac gctggatccg cgccccggca gcgggcgcga gcccggtctg cggcgcgcca
    10741 tcgaactggc gctggcggac gccggcgtcg caccggccga ggtggacgtc gtcttcgccg
    10801 acgccgccgg ctcaccggag ccggacgcgg tggaagtggc ggccgtggcc agtgtgttcg
    10861 gaccgcgcgc ggtaccggtc accgcgccga agaccatgat cggccggctc caggcgggcg
    10921 gcgccccggt ggacgtggtg accgccgtcc tcgccatccg cgaaggcctg atcccgccga
    10981 ccgccgacgc ggagtccgcc acggcccgcg agctggacct ggtcgtcgga cggccccgga
    11041 ccgcctcggt cggcaccgcg ctggtgctcg cgcgaggaca cggcggattc aactcggccg
    11101 tcgtgctgcg ggccgtcgac tgaccggccc gccaccccga agaccgcgcc cgcggccgtc
    11161 tccccccgga cggtccgcgg gcgcctcatt tcacccgtgg cccgtccggg cgtacgggag
    11221 tcaaggaagg gatcgaccgt gtccaagcag gagttcaccc tcgaagacct caagcgcatc
    11281 cttctggaag gcgccggcgc ggacgagggc gtcgacctcg acggcgacat cctcgacacc
    11341 gatttcgagg aactcggcta cgagtcactg gcgttgctgg agaccggcgg ccggatcgag
    11401 cgcgagtacg ggatcacgct cgacgacgac gtgctcgccg acagccgcac gccgcgctcg
    11461 ctgatagccg ccatcaacgc cgcgttccag ggcctcgtcg aggcctgagc ccccctcgcg
    11521 ccaccgcacc accacccctc tgtccggcgg ggccgccgca cctgtgcgcg acggccccgt
    11581 cgaggcgtaa cagcccactc ttctcttctt gttgggagac cagaaacatg tcggatcagg
    11641 acaagcgcgt cgccgtcgtc accggagcca ccagcggcat cggactgtcc gtcgcgcgcc
    11701 tgctggcctc acagggccac cgtgtgttca tcggcgcgcg cagcgcggag aacgtcgccg
    11761 cgaccgtcaa ggagctcgtg gccgagggcc tcgacgtcga cggcgcggtg gtggacgtcc
    11821 gcagcgacgc cgatgtcgag gcctggatcc aggccgccgt ggaccgcttc ggaaccgtcg
    11881 acgtcgtcgt caacaacgcg ggccgctccg gcggcggcgt caccgcggac atcgacccgg
    11941 agctgtggca cgacgtcatc gacaccaatc tcaactcggt cttccgcgtc acgcgttcgg
    12001 cgctgaacac cggcggcctg cggtccaaga gccgcggccg gatcatcaac atcgcctcca
    12061 cggccggcaa gcagggtgtg gtgctcggtg cgccgtactc cgcgtccaag cacggcgtgg
    12121 tcggcttcac caaggcgctc ggcaacgagc tggcgccgac cggcatcacc gtcaacgccg
    12181 tctgccccgg atacgtcgag acgccgatgg cgcagcgcgt gcggcagggg tacgccgcgg
    12241 cgtacgacgc caccgaggac gcgatcctgg agaagttcca ggcgaagatc ccgctcggcc
    12301 gctactccac gccggacgag gtcgccggac tcgtcggcta cctggcctcg gacaccgcgg
    12361 cctccatcac ctcgcaggcg ctcaacgtct gcggcggact cggcaacttc tgagccgtac
    12421 cgatccgggc cgaagcggtc cggtacccac ccgacacgac caccgaggag tacgagcatg
    12481 tcgcagcccg gcctgcgcga ggtggagcac gagatcacgg tctccgctcc cgccgccgcc
    12541 gtctaccgtc tgatcgccga ggtccgcaac tggccccgga tcttcccgcc gaccatctac
    12601 gtcgaccacg tcgaggagaa cggcgacgag gagcgcatcc gtatctgggc cacggccaac
    12661 gacgaggcca agaactggac ctcgcgccgc acgctggacc cggaaggcct gcggatcacc
    12721 ttccgccagg aggttccggc gccgccggtc gccgccatgg gcggcgcctg gatcatcgag
    12781 ccgctcggcg acgccgagtc acggatccgt ctgctgcacg actaccgcgc ggtcgacgac
    12841 gacccggcgc acctggagtg gatcgaccag gcggtcgacc gcaactcccg ctccgaactg
    12901 gcggccctga agggcaacgt cgagaaggcg cacgccgagg aggggctgac gttctccttc
    12961 gaggacacgg tgcgggtcga cggcgcggcg aaggacgtct acgacttcgt caacgaggcc
    13021 gacctgtggc acgagcggct gccgcacgtc gccaccgtac ggctgcgcga ggacactccc
    13081 ggcctccagg agctggagat ggacacccgg gccaaggacg gctcgaccca caccaccaag
    13141 tcgtaccggg tgacctttcc gcaccatcgg atcgcctaca agcagaccac gctgccggcg
    13201 ctgatgaccc tgcacaccgg ctactggacc ttcgccgagg acgaccgggg cgtgctggcc
    13261 tcctcccagc acacggtcac catcaacacc gccaacatcg cccgcgtcct cggcccggag
    13321 gccaccgtcg aggacgccaa ggcgtatgtg cacaccgcgc tgtccaccaa cagcacggcc
    13381 acgctgaacc acgccaagcg gttcgccgag gagcgtgccg cgggccggcg gggctgaccg
    13441 tgccggagga cgacgacgcg cggatcgtcg tggtcggcgc gggcccggtc gggctgctgc
    13501 tcgccgggct gctgcgccgg tccggcgcgg acgtggtcgt cctcgaacag ctcaccgcgc
    13561 ccaccaccga gtcccgcgcc tccaccctgc acgcccgcac catggagatc ctcgacggct
    13621 gcggtgtgcg ggactggctg ggcgcggtgg agcgcgagcc gcgcgggcac ttcggcggca
    13681 tcggcctcga cctgacgctg cccgtccccc atccgggcca gtggaaggtg ccgcagacgc
    13741 ggctggagga ggtgctcgcg cggtgggcac gggagctcgg tgtgcggatc cggcgcggcc
    13801 acgaggtgat cgggctgacg cgggccgcag accacgtgac cgtggacgta cgacggcacg
    13861 gtccgggccg tgcggtccgc ggcacggtcc gggcccgctg gctggtgggc tgcgacggtg
    13921 agcgcggcgc ggtgggccgg ctcggcgggt tcacgttcac cggcggcccg gcacggcggg
    13981 aactgctgcg ggccgatgtg gcgggcctga ccatcgcggc ccggcgcttc gagcgggccg
    14041 aacggggcct gctggtcgcg gctccccttc ccggcggcgt gacccgcgtc atggtccacg
    14101 agcgcggcgc ggagccgctg cccggtccgc cccggttcgc ggacctggtg gcggcctggc
    14161 ggcgggtcgc cggggaggac atcgcgggcg gcgtgccgct gtgggtgaac tccttcgacg
    14221 acgcctgccg ccaggccgac cggtaccgga tcggccgtct gctgctggcc ggggacgcgg
    14281 cccaccggca gctgccgatc ggcggccagt ccttgaacct gggcctccag gacgcctggg
    14341 acctgggccg gaagctggcg gcggtggcct gcggccgggc ccccgccgcg ctgctcgaca
    14401 gctatcacga cgagcggcac cgagccggcc ggcaggtgca ggacgacgta cgggcgcagg
    14461 cgctgctgct gttcggcggg ccggaggtgg acgccgtccg tcaggtgctg gcggagctga
    14521 ccggccacga gcgggtccgc gtccacctgg cccggcggat cggcggctgg ccggaccggc
    14581 cggacggccg tccggcgacg gcaggcaccg gcacccacga ccacgaccac gaccacggag
    14641 acgaccacgg agccggcgac ggcgatgtgc gagggagaag aggtgaggcg atgggcaggc
    14701 tgacgggccg tacggccctg gtcaccggat cgagccgcgg catgggccgg gcgaccgcga
    14761 tccggctggc ggcggacggc gcgctggtcg cggtccacta cgcggagaac aaggacgcgg
    14821 ccgccgaggt ggtcgccgcg atcgagtcgg acggcggacg ggccttcgcg gtgggcgcga
    14881 ggctcggtgt gcccggagac gtcgaggagc tgttcggcgc cctggagccg gccctgctcg
    14941 accgcaccgg ctccaccgat ctgaacatcc tggtcaacaa cgccggagtg atgagcggga
    15001 cggagccgct cagcaggacg acggagggct tcgaccggct gttcgccgtc aacgccagag
    15061 cgccgtactt cctgatccgg cgggcgctgg agaacatgcc ggacggcggc cgcatcgtca
    15121 acatctcgtc cggcctgacg cggtgcgcga atccggacga gatcgtgtac gcgatgagca
    15181 agggcgcgct ggagcagctc gccctgcact tcgccaagct cctcggtccg cgcggcatca
    15241 ccgtcaactc ggtggccccc ggcatcaccc gcaacgacca gccggtcttc cggatcgcgg
    15301 aggcggtcga ccagatggcc gcccggtccg tgttccaccg gatcggcgag ccggaggaca
    15361 tcgccgacgt ggtggcgttc ctggccacgg acgaggcccg ctggatcacg gggtccttcg
    15421 tggacgccac cggcggcacg ctggtcggct gatggggccg ggccccgtcg gccctccggc
    15481 ggtccggcgg acgccgtggc cgctggtctg cgtgctggcg gccacgatgc tcgtcgacgc
    15541 gctggaggtc tccgccgccg tggtgtccgc cccggtcgtc ggagacgcgc tggacctggc
    15601 accggccgtg ctgttctggc tggtcggagg gttcgccgcc ggattcgcgg cggtgctgcc
    15661 ctgggccgcc gcgctgggcc gccggttcgg ccggcggcgc gtccagctcg tcgcgctcgc
    15721 ggtgttcgcg ctggcgtccg cggcgagcgc ggccgccgac tccggcggct ggctgatcct
    15781 cggccgtgcg gtcaagggcg gctgtgcggc gctcaccgcg ccgaccgggc tcgccatcat
    15841 cctggccgcc gtcccggacg ggccggaccg ccgtcgtgcg gtctccgggt acgcgctgtg
    15901 cggcaccgcc ggattctgcg gcggactgct gctggcgggc ctgctgaccg gagtggactg
    15961 gcggctcgtg ccggccctgc cggtgccggc ggcgctgctg ctgctggttc tcgccgcccg
    16021 gctcgtcccg cgcgatccgc cggtccgccg acgggcccgt ccgcgggtcc gcccggggcg
    16081 gccgtcggcc ggaccgcgtg tgctgtggcg ctgccggccg ctgcggcgcg ccgcgctgac
    16141 ggccgccgcg ttcaacgggg cgtacgtcgt cctgctgctc gtcaccgcct ggcagctgca
    16201 ccaccgcggc ggctggaccc cgttgcggac ggccctggtg ttcctgcccg cggcggcccc
    16261 ggcggcgctg accgccctgt ggtcggcgcg gatcgccgtc cggctgggcc cggaccggtc
    16321 ggcggccgcc ggagccgtgc tcgccgtcgt cggctgtctg ctcgtgccgc gcgacgccgg
    16381 agcggccggc tcgggcgcgg ccggactgct gccggcgacc gcggtgctcg gcctggcgtt
    16441 cctcctggcc ttcaccgcgc tgcacctcca ggcggtcgac gcggtcccgg aggagctgcg
    16501 tccggcggcg acggccttct accagacctg ggtgcaggcg ggaccggtcc tgctgaccgc
    16561 tccggcggcg gcgctggtca ccgccggagc ggacatcggc ccggcgctgt ggctggtgac
    16621 cgccgtcgcg gcggccggcg ccctggtggc cgtcaccggc ctgcttccgt ccgggccgcc
    16681 cggacctcct tcgacacccc gaccacggag ctctcatgac gacccttcaa ctctcccgta
    16741 cgtacgagac ggaggacggt gacacgatca cgatgactgt cccggacatc gccgtcctgc
    16801 actccgtcga cctggccgaa cgcaccgcga tcctggagcg gtacgtccgc gagcagctcg
    16861 gccgcgtcct cgccgtccac ccgagccggg tcgacaccac cggccggccg atgggctgcc
    16921 tgggcatcgg ctcgatctcc ggcatggaac tgcagtaccg catggaggac gcgctcggcg
    16981 tcgaactcca cctccagagg ctgctgctgg ccaacagcgc ccaggagctg atcgactgcc
    17041 tggcctggca gttcggcccg gaaggcgccg gcaagtacgg gaccgcggtg gcctcatgaa
    17101 cggatcgatc ctgcttccgg ccaccgccac cgagatccgg cagcccggcc cggacgagcc
    17161 gagcgccttc accgtggcgg cggaccggat cgacctgtgg ctgatccacc cgcccgaggg
    17221 cgacgccgcc gggtccctgg cacgggccga gctggacgag cgcgaacggg cccgtgccga
    17281 cgccttcgtc cggccgtccg acggactgct ctacgccgcc gcgcacgtgg cgctccgccg
    17341 gctgatcgcg gcctacaccg ccggccggcc gcaggacgtg cgcttcatgc gcgaggcctg
    17401 ccccggctgc ggcgagagcc acggcagacc cgccgtcgcc ccgccgccac cgccgttgca
    17461 cttctcgctc tcgcacagcg cgggagtggc gctggtcggc gtggccgacc ggccgatcgg
    17521 cgtcgacgtg gagcggctgc cgggcgcgga gaccgtggac atctgctccc ggtcgctgca
    17581 cccggaggaa caggcggaac tgaacgaggt tccggaggga gaagcgcggc ggaagctgtt
    17641 cggccggatc tggacccgca aggaggccta cctcaagggt ctcgggacgg ggctgagccg
    17701 ctcgccggcc gaggactacc tgggagcgga ccgggaccgg catccgggcg actggacgat
    17761 ggtcggcatc ccgtgcgtcg ccacgcacgc ggcgtcggcc gccgtgcgcg gcacgccgcc
    17821 cgccgtcgcc gaggtgcgca ccctgcccgg ggcctggctg acggacggcc gaccgcctgc
    17881 cgccccggcc tgaccgggcc cgctccgccg taccgccgta ccgcacaccg acacgtcgaa
    17941 ccaggaggca cacccatgcc cacagcacag gacagggccg ggacggcgga caccgtccac
    18001 ggccgcgtcg acgcgctcct cgcgatgaag gacagcgcgc gcgccggaga cgccgaggcc
    18061 acgcgacgcc agcacgccaa gggcaagctg accgcgtacg agcggatcgg gctgctgctc
    18121 gacaagggct ccttcaccga ggtggaaggg ttgcggcggc accgcgcgac cggtttcggc
    18181 ctggaggcga agaagccggc cggcgacggc gtcgtcaccg gctggggcac cgtgcacggc
    18241 cggagcgtct tcgtctacgc gcacgacttt agggccttcg gcggtgcgct cggcgaggcg
    18301 cacgccgcga agatccacaa ggtgatggac ctggcggagg cggccggcgc gccgctggtc
    18361 tcgctcaacg acggcgccgg agcccggatc caggaaggcg tcaccgcgct cgccggatac
    18421 ggcggcatct tccggcgcaa cacccgggcc tccggggtga ttccgcagat cagcgtgatg
    18481 ctcggcccgt gtgcgggcgg ggcc
//
