LOCUS       NZ_KL503830            21086 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Streptomyces griseorubens strain JSD-1 scaffold1, whole genome
            shotgun sequence.
ACCESSION   NZ_KL503830
VERSION     NZ_KL503830.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces griseorubens
  ORGANISM  Streptomyces griseorubens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces althioticus group.
REFERENCE   1  (bases 1 to 7563100)
  AUTHORS   Feng,H., Zhi,Y., Sun,Y., Wei,X., Luo,Y. and Zhou,P.
  TITLE     Draft Genome Sequence of a Novel Streptomyces griseorubens Strain,
            JSD-1, Active in Carbon and Nitrogen Recycling
  JOURNAL   Genome Announc 2 (4), e00650-14 (2014)
   PUBMED   24994798
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7563100)
  AUTHORS   Feng,H., Sun,Y., Zhi,Y., Mao,L., Luo,Y., Wei,X. and Zhou,P.
  CONSRTM   Shanghai Jiao Tong University
  TITLE     Draft genome sequence of the novel Streptomyces griseorubens JSD-1
            playing a role in carbon and nitrogen cycle
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7563100)
  AUTHORS   Feng,H., Sun,Y., Zhi,Y., Mao,L., Luo,Y., Wei,X. and Zhou,P.
  CONSRTM   Shanghai Jiao Tong University
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2014) School of Agriculture and Biology, Shanghai
            Jiao Tong University, Shanghai Jiao Tong University, Shanghai,
            China, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2013-12-24
            Genome Coverage                   :: 246x
            Sequencing Technology             :: Illumina Miseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000709915.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:19:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,036
            CDSs (total)                      :: 6,948
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 329
            CDSs (without protein)            :: 328
            Pseudo Genes (ambiguous residues) :: 0 of 329
            Pseudo Genes (frameshifted)       :: 72 of 329
            Pseudo Genes (incomplete)         :: 272 of 329
            Pseudo Genes (internal stop)      :: 8 of 329
            Pseudo Genes (multiple problems)  :: 23 of 329
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:40:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4999496
            Orig. end                         :: 5020582
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KL503830.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(149..1465)
                     /gene="aroA"
                     /locus_tag="DJ64_RS22795"
                     /old_locus_tag="DJ64_11040"
     CDS             complement(149..1465)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522882.1"
                     /locus_tag="DJ64_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11040"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_033272064.1"
                     /transl_table=11
                     /translation="MAPNPTHTALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAGGLRAMGVEIEEGVGPDGTGEAWRVVPAGLRGPATVDVGNAG
                     TVMRFLPPVATLADGPVRFDGDPRSYERPLNGVIDALRGLGARIDDDERGALPMTVHGG
                     GALDGGTVEVDASSSSQFVSALLLSAPRFNQGVEVRHTGSTLPSMPHIRMTVDMLRAVG
                     AQVDTPEAGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALITGGKVVIPDWPART
                     TQPGDRLREIFTEMGGSCELTEYGLVFTGSGAVHGIDVDLGEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGVFHTYEDHRM
                     ATAGAVIGLAVDGVQIENVATTAKTLPDFPELWTGMLGA"
     gene            complement(1552..2274)
                     /locus_tag="DJ64_RS22800"
                     /old_locus_tag="DJ64_11045"
     CDS             complement(1552..2274)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="DJ64_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11045"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_033272656.1"
                     /transl_table=11
                     /translation="MVSTASASLASLWDEVAGTQPDPDLWVVVATLVAALAVVVPQAPW
                     RIARNAITIAHEGGHGLVALLTGRTLTGIRLHSDTSGLTVSRGRPTGIGMILTAAAGYT
                     APPLLGLGGAALLGAGRITLLLWLATALLLAVLVMIRNAYGAVSVLVTGGTFVLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRRHGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSVCSLLGGGRWLLGL"
     gene            2335..3150
                     /locus_tag="DJ64_RS22805"
                     /old_locus_tag="DJ64_11050"
     CDS             2335..3150
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="DJ64_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11050"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_033272063.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEIEKWEPEETLEADYNVAPTKEVYAVL
                     DRPLKDADDPRPVRQLRTLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFTSRR
                     CILPADGYYEWVTGKQERDLEVEGKKKRPRKQPYFVTPADGSVFAMAGLYEFWRDRTLP
                     DDHPRAWWVTCSVITTEAERSPLAVAPAEGPHTLAEIHPRMPLMLTQDRWDAWLDPSRT
                     DPEDLRGLLAPPEPGLMRAYPVTTAVSNVRNNGPELLKELAAPEEGTLF"
     gene            3197..3826
                     /locus_tag="DJ64_RS22810"
                     /old_locus_tag="DJ64_11055"
     CDS             3197..3826
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491194.1"
                     /locus_tag="DJ64_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11055"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_106963435.1"
                     /transl_table=11
                     /translation="MTTETIPTDAGDARITWHHAGRPRLVLAASHGAGGGIEARDLVAL
                     AAVLPAHGVTVALVEQPWRVAGKKVAPAPKTLDTGWRGVWPALTQPGLPVISGGRSAGA
                     RVACRTAVELDAHAVLALSFPLHPPGRPEKSRADELLGAGVPTLVVQGGNDPFGKPAEF
                     PAGDHELVEVPRADHGFAVPKRADLTQEEALRVVTDAVVRWTAGLA"
     misc_feature    complement(4016..4030)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            4086..4772
                     /gene="sigR"
                     /locus_tag="DJ64_RS22815"
                     /old_locus_tag="DJ64_11060"
     CDS             4086..4772
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="DJ64_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11060"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_033272060.1"
                     /transl_table=11
                     /translation="MGPVPGTDAGTEHGQAEQPEGQGDTRAESTAERSARFERDALEFL
                     DQMYSAALRMTRNPADAEDLVQETYAKAYGSFHQFREGTNLKAWLYRILTNTFINSYRK
                     KQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEFRIA
                     VYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGESNE
                     AKGSGS"
     misc_feature    4108..4123
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     gene            4769..5071
                     /gene="rsrA"
                     /locus_tag="DJ64_RS22820"
                     /old_locus_tag="DJ64_11065"
     CDS             4769..5071
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522887.1"
                     /locus_tag="DJ64_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11065"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_033272059.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDREMPDADCQKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPGDLRSKVMGRIELIRSGHNVPEKDVTAAPQES"
     gene            5211..6590
                     /locus_tag="DJ64_RS22825"
                     /old_locus_tag="DJ64_11070"
     CDS             5211..6590
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134738.1"
                     /locus_tag="DJ64_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11070"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_037641482.1"
                     /transl_table=11
                     /translation="MEALPARARVYLVGVTLLGLCCLLPLPGVPRPGVLSSLPDPRVPW
                     WPVVLLAALYAGCERLARSRLVAGPHPGGAFHPVLLAGAFLLPPTAAALVALPGALLLP
                     VEHGPRLARRLWRTGRLVVAVWAASLVHLKTGGRDAVAHCDMPGALATAGVAVLAFCLV
                     LTLLDGGVLVPAPGGLPRSRPVAAWWRLFLGSLAPLTVHGLAGLMMALLWRSPYGPVAA
                     LLVLLPMGVSWWAFAQYHRERAAHQATIRALVQAVDIKDGYTRGHSERVGRASMLIARE
                     LGMDDDRVETLRFAGILHDVGKLGVPTRLLTKNGPLTPEERRVIELHPEYGHEMVRGIS
                     FLGEARAAVLHHHERLDGTGYPYGLAGGQIPESARVVAVADAFDAMTSTRSYSRARPVP
                     VALEELERCAGTHFDPRMVKALVTAIGRTGWHPAVTADEPRRTAVPGPAGHVTGRPGAR
                     R"
     misc_feature    5220..5222
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6587..7849
                     /locus_tag="DJ64_RS22830"
                     /old_locus_tag="DJ64_11075"
     CDS             6587..7849
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522889.1"
                     /locus_tag="DJ64_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11075"
                     /product="HD domain-containing protein"
                     /protein_id="WP_193456176.1"
                     /transl_table=11
                     /translation="MRPRAHTVPLHTVVHLCAAVLAAGSLGTTLYHGVDDRSTALAFGT
                     LVAVGELTRRGGRWIREPAPVAAAGSLAYALLGEVAGRPAGHGAAQVVTVVLAASLLGS
                     VPHVGRGDGPALDPVTRRVLTVGFVAVCFHPLHARGAFEDFSGPGHALLLLVLLTLTAL
                     CDAVLAAALAHSRTGWPFPPLLRDELRAVPGIGAAVVATGAVMALGAAVVGLWALPVFS
                     VPLLLAQLSHRRYTAVRATYRQTIASLARATEIAGYTPHGHSRRVAALSQAVGRDLGLT
                     EPELTVLEYAALMHDIGQLSLVDPVPEGATAGLPPAEQRRIALLGGAVVRQTGVDPRVA
                     GIVERQADPHAEQPLAARIVRVVNAYDEKCREGGPGGPLTALEELRLGAAGEYAPEVVE
                     ALARVLSRDTEGTREQVDRSW"
     gene            8006..8986
                     /locus_tag="DJ64_RS22835"
                     /old_locus_tag="DJ64_11080"
     CDS             8006..8986
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="DJ64_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11080"
                     /product="hypothetical protein"
                     /protein_id="WP_019522890.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKVPGPATDSGEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERSTAAGHTYPVFDEIELWAPSPVPTWVVLLEAASEADRD
                     ALEQLASDAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGIAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            9134..9784
                     /gene="def"
                     /locus_tag="DJ64_RS22840"
                     /old_locus_tag="DJ64_11085"
     CDS             9134..9784
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="DJ64_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11085"
                     /product="peptide deformylase"
                     /protein_id="WP_033272057.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGYVIDTEDCEKREAEWRERGTSRPIT
                     VVGNPVLHKECKDVTDFGEEFQQLVADMFASQRTAEGVGLAANQIGVDLKVFVYDCPDD
                     EGVRHVGVVCNPKLVELPAERRRLDDSSEGCLSVPTAYAPLARPDYAEVTGQDEKGNPI
                     RVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKAALKQMAENEPRYPVVAND"
     gene            10001..11086
                     /gene="cyc1"
                     /locus_tag="DJ64_RS22845"
                     /old_locus_tag="DJ64_11090"
     CDS             10001..11086
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="DJ64_RS22845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11090"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_033272654.1"
                     /sec_met_domain="T1TS (E-value: 9.8e-66, bitscore: 221.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHALSHGSTSTPTTIAVPPALSLPVIEAAFPRRLHPYWPKLQRET
                     RAWLLEKRLMTPEKVEEYADGLCYTDLMAGYYLGAPDEVLQAIADYSAWFFVWDDRHDR
                     DIVHGRPDAWRRLKDLLHSALDRPGDHLGHQDPVVAGLADSVRRLHAFLPDTWNARFAR
                     HFHAVIEAYDREFHNRTEGVVPTVEEYLELRRLTFAHWIWTDLLEPSAGYELPDAVRKN
                     PAYRKPALLSQEFAAWYNDLCSLPKEIAGNEVHNLGISLVTHEGMTLEEAIADIRRRVE
                     ECISEFLDAEQEALRFADRLDDGTVGGKETSAAVRACVGNMRNWFSSVYWFHHESGRYR
                     VDSWDDRSTPPYVDNATEGEK"
     misc_feature    10883..10885
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11083..12450
                     /locus_tag="DJ64_RS22850"
                     /old_locus_tag="DJ64_11095"
     CDS             11083..12450
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190553.1"
                     /locus_tag="DJ64_RS22850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11095"
                     /product="cytochrome P450"
                     /protein_id="WP_033272056.1"
                     /sec_met_domain="p450 (E-value: 2.8e-69, bitscore: 232.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVRPEDTAATAEPPVAGGAVPLLGHGWRLVRDPLAFLSQLR
                     DHGDVVRLKLGPKTVYAVTTPALTGAVALSPDYIIAGPLWESLESLLGKEGVATANGPL
                     HRRQRRTIQPAFRLDAIPAYGPIMAEEAYALVERWRDADGVLDITYESFRVAVRVAARC
                     LMRGGYMDAHADRICADLTTLFAGMYQRMVVPLGPLYKIPLPANREFNRALADLHVLVD
                     EIVADRRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVIAILTPGAETVGSTIMSLL
                     LVLTEHPELGDKIRDEVKSVVGDRPVAFEDVRKLTYTANVVTETLRLYPAVWILTRRAV
                     ADTELGGYRIPKGADLIYSPFAVQRDRRSYERNEDFDPDRWLPERSKDVPKYAMSPFSV
                     GNRKCPSDHFSMAELTLVTAVVAHAYGFEHASDSDPRPRIGITLRPRRLMLRALPR"
     gene            complement(12473..13435)
                     /locus_tag="DJ64_RS22855"
                     /old_locus_tag="DJ64_11100"
     CDS             complement(12473..13435)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700022.1"
                     /locus_tag="DJ64_RS22855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11100"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_037641485.1"
                     /transl_table=11
                     /translation="MLRNVAAVLLDGVNPFELGVVCEVFGIDRSDDGLPVYDFAVVSAE
                     GASVRASAGFTLQTEHGLDRLDAADLITVPAGASYTSREFPPEMLDALRRAVDRGARVL
                     SVCSGAFVLAAAGLLEGRRAAVHWKHAEELSRRYPHLTVEPDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGPEVANRIARRMVVPPHRDGGQAQYIERPLPEPGGDSVAGVLVWME
                     QHLDEEVTVEQLAARALMSPRTFARRFQQETGTTPYRWILRQRVLLAQHLLERTDETVD
                     AIAGRAGFGNAAALRHHFVRAVGTTPQSYRRAFRGPEAA"
     gene            13529..13750
                     /locus_tag="DJ64_RS22860"
                     /old_locus_tag="DJ64_11105"
     CDS             13529..13750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700023.1"
                     /locus_tag="DJ64_RS22860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11105"
                     /product="hypothetical protein"
                     /protein_id="WP_203550129.1"
                     /transl_table=11
                     /translation="MNTTQTEALIAMVAVLGLFVLMVAPAVIGILRDRRIDRQIRRARA
                     TLVTEPPGMPAASRPEHRAASRRHARAA"
     gene            complement(13772..14728)
                     /locus_tag="DJ64_RS22865"
                     /old_locus_tag="DJ64_11110"
     CDS             complement(13772..14728)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142309.1"
                     /locus_tag="DJ64_RS22865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11110"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_203588083.1"
                     /transl_table=11
                     /translation="MRYPDFYERYRDAIKNTWHVEEVDLHSDVADLAKLTPEEQHLIGR
                     LVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPD
                     DRAAAFAAVENIPSIREKAEFCFRWMDSVEKIDRLESRADRRRFLLNLICFAACIEGLF
                     FYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVVDTVRKEEPELFDEELGR
                     QVTDMLREAVEAELQFARDLCGDGLPGMNTASMRQYLECVADQRLVRLGFAPVYGSENP
                     FSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(14785..17242)
                     /locus_tag="DJ64_RS22870"
                     /old_locus_tag="DJ64_11115"
                     /pseudo=""
     CDS             complement(14785..17242)
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009068626.1"
                     /locus_tag="DJ64_RS22870"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11115"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTIAPADPASATRVTEDSDGPGAALLRTLTQLTADLPDADAGRVA
                     AAALRGRSASADEAELRADRRPARRRRRPGGRGRAARPVRLRRRGGAAGPGHRGGGRAD
                     LRGPRLLPARRPAAHPRHPRRGRLAGRHLVHRLGGRRSPGGPDRRPHRRVRPAPRGPSG
                     RAGRHGRRRPVRLLRPAHPAQPLPAAPPGHPQGRRDAPALPAAGGLRARRGRERAGAGG
                     RRRAVRADEPAGLPALLPHAVQLRHPPPADVVLLPPGLPQGRAGLPLRALPPGRPPVEA
                     RRRHRPVLLPRPRPGFADPRHQRALQRHRPVPEDAGRLGRRREPGRPAQGRRRGLPGDL
                     ARGRRGVPGAARQHR"
     misc_feature    17293..17304
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     regulatory      complement(17367..17536)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17488..17501)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(17495..17509)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17526..17540)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            complement(17588..18091)
                     /locus_tag="DJ64_RS22880"
                     /old_locus_tag="DJ64_11120"
     CDS             complement(17588..18091)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="DJ64_RS22880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11120"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_033272051.1"
                     /transl_table=11
                     /translation="MDIVIRPATPGEHADLGEITAQAYLGDGLLDFGESDSYLDELRDV
                     GKRAAAAEVLVAVADGALLGGVTFVPGPGPMADIAEPGEAEIRMLAVSPAHRGRGAGEA
                     LVRACVDRARALGRTRMVLSTQRTMHSAHRVYERLGFTRAPGRDWNPLPELDDIMLLVY
                     ELTL"
     gene            complement(18172..19800)
                     /locus_tag="DJ64_RS22885"
                     /old_locus_tag="DJ64_11125"
     CDS             complement(18172..19800)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="DJ64_RS22885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11125"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_037641495.1"
                     /transl_table=11
                     /translation="MNDGVNGVALAVFIFFFVLVTVMGFLAARWRKAANEHTLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     ENTNWFIKDMPLLLAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDEIFASAQEAYSETNPATGAPRGALVPGEAGQWTYATLALGSALALFMYPHSITATLS
                     SRSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVQNGQLAIPQLFENMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPKQETAVSKIVSLLVKVGAL
                     VFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALIGGWAVGMIYGTVAAY
                     GVASPTQKHFGGSAKEIPGIGEIGYIGLTAFVINVLVTVVLTFVMRAVKAPDGVDETEP
                     RDYTADAGDPGVQVELPPATADSKH"
     gene            complement(19797..20018)
                     /locus_tag="DJ64_RS22890"
                     /old_locus_tag="DJ64_11130"
     CDS             complement(19797..20018)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522900.1"
                     /locus_tag="DJ64_RS22890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11130"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_051724313.1"
                     /transl_table=11
                     /translation="MRVVIGLCLLAPFVAMLWVGSYAKTDPVFIGIPFFYWYQMLWVLI
                     STALTMIAYKLWQRDQRARSAAKGGAEQ"
     gene            complement(20253..21017)
                     /locus_tag="DJ64_RS22895"
                     /old_locus_tag="DJ64_11135"
     CDS             complement(20253..21017)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="DJ64_RS22895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_11135"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_033272048.1"
                     /transl_table=11
                     /translation="MSTDVSSTENEGGTAVRTARVPKYYRLKKHLLDMTETAPPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDLGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLTKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDRGGQPVEWVRSVYRGDRYKFVARLKRPQD"
ORIGIN
        1 ggccccggtc gaccgtgagc accatgccct cggcggcgtc ctcgtgcttg ggcctgatgt
       61 gggtgcgcgg ccggttgccc ttgcggttgg ggcgcgagcg gatgtcgtcc tcgtcggtgt
      121 gcttgccgta gcggcgcatc gtgaacccct acgccccgag catcccggtc cacagctcgg
      181 ggaagtccgg cagggtcttc gccgtggtcg ccacgttctc gatctgcacg ccgtcgaccg
      241 ccaggccgat gaccgcgccg gcggtggcca tgcggtggtc ctcgtaggtg tggaagacgc
      301 cgccgtgcag ccggcgcggg cggatgtgca ggccgtcggc cgtctcggtg acgtcgccgc
      361 ccagctcgtt gatctccttg gtgagggcgg ccagccggtc cgtctcgtgc agccgcagat
      421 gggccacgcc ccgcagggtc gacggggagt ccgcgagggc cgcgaccgcc gcgatgcccg
      481 gcgtcagctc gcccacctcg ccgaggtcca cgtcgatgcc gtgcaccgcg ccggagccgg
      541 tgaacaccag cccgtactcg gtcagctcgc aggaaccgcc catctcggtg aagatctccc
      601 gcagccggtc gccgggctgg gtggtgcgcg cgggccagtc ggggatcacc accttgccac
      661 cggtgatcag cgcggccgcg aggaacggct gggcgttgga caggtccggc tcgaccgtca
      721 ggtcccggcc gagcagggcg cccggcgtga cccgccagac gttcggctcg ccgcccgcct
      781 cgggggtgtc cacctgggcg ccgaccgcgc ggagcatgtc gaccgtcatc cggatgtgcg
      841 gcatcgacgg cagcgtcgac cccgtgtgcc gcacctcgac gccctggttg aagcgcggcg
      901 ccgacagcag cagggcgctg acgaactgcg acgacgagga cgcgtccacc tcgaccgtgc
      961 cgccgtccag cgcgcccccg ccgtgcaccg tcatcggcag ggcgccccgc tcgtcgtcgt
     1021 cgatccgggc gcccagcccg cgcagcgcgt cgatgacgcc gttcagggga cgctcgtagg
     1081 accgcgggtc gccgtcgaag cgcaccgggc cgtccgccag ggtggccacc gggggcagga
     1141 agcgcatcac cgtgcccgcg ttgcccacgt ccacggtggc cggaccgcgc agaccggccg
     1201 gcaccacacg ccaggcctcg cccgtcccgt cgggaccgac gccctcctcg atctccacgc
     1261 ccatcgcgcg cagcccgccc gccatcagca gcgtgtcgcg cgagcgcagg ggacggcgca
     1321 gccagcccgg ctcggaggcg agggcggcga ggacgagagc acggttggtg accgacttgg
     1381 acccgggcac gtggaccgtc gcgtcgacgg ctccgctcgc gtgcggggcg ggccagaggg
     1441 cggtgtgcgt ggggttcggg gccatggggc cactttataa gggagtgagg agcccggccg
     1501 ttccgtgccc gccaggcgga acgccgtccg gtcgaccgac cgcaggcccg gtcacagacc
     1561 cagcagccag cgccctccgc ccagcagcga gcacaccgac accgcgtgga agaggaacag
     1621 ccacagcccc gccggcacgt gcgtcagccg ggacagctgg tccgcgtccg agtccccggc
     1681 gcccccgtgc cgccgcttgg cctggagctc gaacgccgga cgcaccccgc ccagcagcag
     1741 gaaccacacc acggcgtacg cgaacgccgc ctgcacctgc gggccggcga gccacgacac
     1801 cagcacgaac gtgcccccgg tgaccagcac cgacaccgcg ccgtaggcgt tgcggatcat
     1861 caccagcacc gccagcagca gcgcggtggc cagccacagc agcagcgtga tgcgccccgc
     1921 gccgagcagc gccgccccgc cgaggcccag cagcggggga gcggtgtagc cggccgcggc
     1981 cgtgaggatc atgccgatgc cggtcggcct gccgcggctg acggtcaggc cgctggtgtc
     2041 ggagtgcagg cgtatgcccg tcagggtgcg gccggtgagc agggccacca ggccgtgccc
     2101 gccctcgtgc gcgatggtga tcgcgttccg cgcgatccgc cagggcgcct gcggcaccac
     2161 cacggcgagg gccgccacca gggtcgcgac gaccacccac aggtccgggt cgggctgggt
     2221 gcccgcgacc tcgtcccaga gggaggcgag ggacgcggac gcggtgctga ccatgctcgt
     2281 catgtgtgtt ggatcgctcc ctgtgcgcgt gcggagtctg gcagtgttgc acgtatgtgc
     2341 ggacggtatg cagcgagtcg gaggcccgag gatctcgccg ggatcttcga gatcgagaag
     2401 tgggagcccg aggagaccct ggaggccgac tacaacgtgg cgccgaccaa ggaggtctac
     2461 gccgtcctcg accgtcctct gaaggacgcg gacgaccccc gcccggttcg gcagctgcgc
     2521 acgctcaagt ggggactggt gccctcctgg tccaagaccc ccgagggcgg cgcccggatg
     2581 atcaacgcgc gcgcggagac cgtccacgag aagccgtcgt accgccgtgc cttcacctcc
     2641 cgccgctgca tcctccccgc cgacggctac tacgagtggg tcaccggcaa gcaggagcgc
     2701 gacctggagg tcgagggcaa gaagaagcgg ccccgcaagc agccctactt cgtcaccccg
     2761 gccgacggct cggtcttcgc gatggccggg ctgtacgagt tctggcgcga ccgcaccctg
     2821 cccgacgacc acccgcgggc ctggtgggtg acctgctcgg tgatcaccac cgaggcggag
     2881 aggagcccgc tggccgtggc cccggcggag ggcccgcaca ccctggccga gatccacccg
     2941 cggatgccgc tgatgctcac ccaggaccgc tgggacgcct ggctcgaccc ctcccgcacc
     3001 gaccccgagg acctgcgcgg cctgctcgcc ccgccggagc ccggcctgat gcgcgcctac
     3061 ccggtcacca ccgccgtcag caacgtccgc aacaacggtc cggagctgct gaaggagctg
     3121 gccgccccgg aagagggcac actcttctga cgtgaccacc gagcccgcag cgacccccga
     3181 gtccgacgtg accgacgtga ccaccgagac gatccccacg gacgccggcg acgcccgcat
     3241 cacctggcac cacgccgggc ggccgcgcct cgtcctcgcc gcgagccacg gcgcgggcgg
     3301 cggcatcgag gcccgtgacc tcgtcgcgct cgccgccgtc ctccccgcgc acggcgtgac
     3361 cgtcgccctc gtcgagcagc cctggcgcgt ggccggcaag aaggtcgccc cggcgccgaa
     3421 gaccctggac accgggtggc gcggcgtctg gcccgccctg acgcagccgg gcctgccggt
     3481 gatctccggc gggcgcagcg ccggcgcccg cgtcgcctgc cgcaccgccg tcgaactgga
     3541 cgcgcacgcc gtgctcgcgc tgagcttccc gctccacccg ccgggcaggc cggagaagtc
     3601 ccgcgccgac gaactgctgg gcgcgggcgt ccccacgctc gtcgtccagg gcggcaacga
     3661 ccccttcggg aaacccgccg agttccccgc gggcgaccac gaactggtgg aggtcccgcg
     3721 ggccgaccac ggcttcgccg tgcccaagcg ggcggacctc acacaggagg aggccctccg
     3781 ggtcgtcacg gacgcggtcg tgcggtggac ggcgggcctc gcctgaggag cgccgggaat
     3841 gcgtggaccg tccccgctgt tgtggggtgc gtacgtgccg gtcgaacggc accgccgccg
     3901 taggagagga agtccaccgc atgggttcca cgttctgccc gagccgcagt gcccgcgccg
     3961 acctcgactg gacggtgctg cacgcggcca agaccgcccc gattcgggcg gcgggcggac
     4021 cggatcgtcg tctatcctcc gattcgggtg aggccggtct cggtctcacg acgacacttg
     4081 aggaggtggg tccggttccc ggtaccgacg cagggaccga acacggccag gcggagcagc
     4141 ccgagggcca gggcgacacg cgcgcggagt cgaccgcgga gcgcagcgcg cgcttcgaac
     4201 gggacgcgct cgagttcctc gaccagatgt actcggcagc gctgcgcatg acgcgcaacc
     4261 cggccgacgc cgaggacctg gtgcaggaga cctacgccaa ggcgtacggg tccttccacc
     4321 agttccgtga gggcaccaac ctcaaggcgt ggctgtaccg gatcctgacc aacaccttca
     4381 tcaactcgta ccgcaagaag cagcgcgaac cccagcgctc cgcggccgag gagatcgagg
     4441 actggcagct cgcgcgcgcc gagtcgcaca tgtccacggg tctgcgctcc gccgagtcgc
     4501 aggcgctgga ccacctgccg gactcggacg tgaaggaagc cctgcaggcg atcccggagg
     4561 agttccgcat cgcggtctat ctcgccgatg tcgagggctt tgcctacaag gagatcgccg
     4621 acatcatggg gacacccatc ggaacggtga tgtcccgcct ccaccgggga cgtcgccagc
     4681 tgcgcggcat gctcgaggac tacgcccgcg agcgcggact ggtcccggcc ggtgccggag
     4741 agtcgaacga agcgaaaggc tcggggtcat gagctgcgga gagccgcacg agacggattg
     4801 cagcgaaatc ctcgatcatc tctacgagtt cctcgaccgt gagatgccgg atgccgactg
     4861 ccagaagttc gagcaccact tcgaagagtg ctcgccctgc ctggagaagt acgggctgga
     4921 gcaggcggtc aagaagctcg tgaagcggtg ctgcgggcag gacgacgtgc cgggcgacct
     4981 gcgctcgaag gtcatgggcc gcatcgagct gatccgctcc ggacacaacg tgcccgagaa
     5041 ggacgtcacg gccgctccgc aggagtcctg acacctcccc acccccgggg ccgcgtcacc
     5101 cgattgtgct aatccgcggg cggtacgccc acgtcggcgc cctcccccgc cctaggctcc
     5161 aggagccggc gggcgacgga aggcgcgcgg cacggtcggg ggaggggctc atggaggcgt
     5221 taccggcgcg ggcccgggtg tatctcgtcg gcgtcaccct gctgggactg tgctgtctgc
     5281 tcccgctgcc gggcgttccc cggccggggg tgctgtcctc cctgcccgac ccgcgcgtcc
     5341 cctggtggcc ggtcgtcctg ctcgccgccc tgtacgcggg ctgcgagcgc ctcgcccggt
     5401 cccgtctcgt cgccggaccg cacccaggag gcgccttcca ccccgtgctg ctcgccgggg
     5461 ccttcctgct gccgcccacc gccgccgccc tcgtggcgct gcccggggcg ctgctgctgc
     5521 ccgtcgagca cggcccgcgt ctcgcgcgcc ggctgtggcg cacgggccgg ctcgtcgtcg
     5581 ccgtgtgggc cgccagcctg gtgcacctga agaccggcgg cagggacgcg gtggcgcact
     5641 gcgacatgcc gggcgccctc gccacggcgg gcgtcgccgt gctggcgttc tgcctcgtcc
     5701 tcaccctgct cgacggcggt gtcctggtgc ccgcccccgg cgggctgccg cgcagccgtc
     5761 ccgtggccgc ctggtggcgg ctgttcctcg gctccctggc accgctcacc gtgcacggcc
     5821 tggccggact gatgatggcc ctgctgtggc gcagccccta cgggccggtc gcggcgctgc
     5881 tggtgctgct gccgatgggc gtctcgtggt gggcgttcgc ccagtaccac cgggagcgcg
     5941 ccgcccacca ggccacgatc cgcgcgctgg tgcaggccgt cgacatcaag gacggctaca
     6001 cgcgcggcca cagcgagcgc gtcggccgcg cctccatgct gatcgcgcgc gaactcggca
     6061 tggacgacga ccgggtcgag acgctgcgct tcgccggcat cctgcacgac gtcggcaagc
     6121 tcggcgtgcc cacccggctg ctcaccaaga acggcccgct cacccccgag gagcggcggg
     6181 tcatcgaact gcaccccgag tacgggcacg agatggtgcg cggcatctcc ttcctcggcg
     6241 aggcccgcgc cgccgtgctg caccaccacg agcgcctcga cggcaccggc tacccctacg
     6301 ggctggcggg cggtcagatc ccggagtccg cgcgggtggt cgcggtcgcc gacgccttcg
     6361 acgcgatgac ctccacccgc agctacagca gggcgcgccc ggtgcccgtg gcgctggagg
     6421 agctcgagcg gtgcgcgggc acgcacttcg acccgcggat ggtcaaggcg ctcgtcaccg
     6481 cgatcggccg caccggctgg caccccgcgg tgaccgccga cgagccccgg cggacggccg
     6541 tgcccggtcc cgccggacac gtcaccggcc gtcccggggc gcgccggtga ggccccgcgc
     6601 gcacaccgtc ccgctgcaca ccgtcgtgca tctgtgcgcc gccgtcctcg cggccggctc
     6661 gctgggcacg acgctgtacc acggcgtgga cgaccgctcc accgccctgg ccttcggcac
     6721 gctcgtcgcg gtcggcgaac tcacccggcg gggcggccgg tggatccggg agcccgcgcc
     6781 ggtggccgcg gccggctcgc tggcgtacgc actgctcggc gaggtcgcgg ggcggcccgc
     6841 cgggcacggc gccgcccagg tcgtcaccgt ggtgctcgcc gcgtcgctgc tgggcagcgt
     6901 cccgcacgtc gggcgcggtg acgggcccgc cctggacccg gtgacccgca gggtgctgac
     6961 cgtgggcttc gtcgccgtgt gcttccaccc gctgcacgcc cggggcgcgt tcgaggactt
     7021 cagcgggccg ggacacgcgc tgctgctgct cgtcctgctg accctgaccg cgctgtgcga
     7081 cgcggtgctc gccgccgcgc tggcccactc ccgcaccggc tggcccttcc cgccgctgct
     7141 gcgcgacgag ctgcgggccg tgcccggcat cggcgccgcc gtcgtcgcca ccggcgcggt
     7201 gatggcgctg ggcgcggcgg tcgtggggct gtgggcgctg cccgtgttct ccgtgccgct
     7261 gctgctcgcg cagctgtccc accggaggta cacggcggtg cgcgccacct accggcagac
     7321 catcgcatcc ctcgcgcggg ccaccgagat cgccgggtac accccgcacg ggcactcgcg
     7381 ccgggtcgcg gcgctcagcc aggcggtggg gcgggacctc gggctgaccg agccggagct
     7441 gaccgtgctg gagtacgcgg cgctgatgca cgacatcggg cagctcagcc tcgtcgaccc
     7501 ggtgcccgag ggcgccaccg ccggactgcc gcccgccgag cagcggcgga tcgcgctcct
     7561 gggcggcgcg gtggtccggc agaccggggt ggacccccgg gtcgccggga tcgtcgagcg
     7621 tcaggccgac ccgcacgccg agcaaccgct cgccgcccgt atcgtccggg tggtgaacgc
     7681 gtacgacgag aagtgcaggg aaggagggcc cggggggccg ctgaccgcgc tggaggaact
     7741 gcggctgggg gccgccgggg agtacgcgcc ggaggtcgtc gaggccctgg ccagggttct
     7801 gtcccgggac acggagggga cgcgtgagca ggtggaccgg tcgtggtgag agggcggacc
     7861 gggcggtctg gttcccggcc gagctgggta acccatgggt aatgagcgcc ctcgcggccg
     7921 tacgtggttg gatgcgaagg agagggtgtc cgggggtgcc gatcgctgtg gccggcccac
     7981 cgaacggaac tggcaggcgg gaatcgtgag gatcttcggc aagggacgtc accggccctc
     8041 cgcctcctgg cggcaggcca cggaccgcgc gttcacgctc atcggcgacg gccggtacga
     8101 ggacgcgggc gcgctgctga cccgggccgc cgacctggag ccctggctgt cggagtcctg
     8161 gttcaacctc gcgctgctgc acaagttccg gcacgactgg gagcaggcgc gcgcggccgg
     8221 gctgcgcgcc gtcgccctgc tcgaccgcga caccggggcc ccggactggt ggaacgtggg
     8281 catcgcggcc accgccctcc aggactggcc gctggcccgc cgcgcctggc aggcgtacgg
     8341 gctgaaggtg cctggccccg cgaccgactc gggcgagccc ctcggcatgg acctgggcag
     8401 cgcggccgta cggctgtccc cggaggggga ggccgaggtg gtgtgggggc ggcggctcga
     8461 ccccgcccgc atcgaggtgc tgtccatccc cctgccgtcc tccgggcgcc gctggggcga
     8521 ggtcgtgctg cacgacgggg tgccgcacgg cgagcggagc accgccgccg ggcacaccta
     8581 cccggtgttc gacgagatcg agttgtgggc gccctcgccg gtgccgacct gggtggtgct
     8641 gctggaggcc gcgtccgagg ccgaccggga cgcgctggaa cagctcgcct ccgacgccgg
     8701 gttcgcggcc gaggactggt cgtcgtcggt gcggctgctg tgccggatgt gctcggagtc
     8761 gcggatgccg tcggacgagg gtgacgggga gcacctcgat ccgcacgatc acagtgagcc
     8821 ggggcatccc ggaccgttgg ggcatcggac ggacgggcag ttgtgggtgc cggagcggga
     8881 gtgcggcatc gctgccccgg cttctctggt tcgggggttg ttggacgggt gggttgctga
     8941 cagtccggac tctcgggact ggcgggatct cgaagaggtt tgttgaggct cgcggtcggc
     9001 tgcggggccg tggcggctga tcgcgcccac gcggcggagc cgcacgtcga cgctgccccg
     9061 cgccccttga aggagcgctg cacttaccct tgtcacagca gtctcggtca tctcaggaag
     9121 gcacacgtcg gtcatggctc agcaggacac cgatcagcag cacgcgggcg tgctccccgt
     9181 cgacgacgag ggctacgtca tcgacacgga ggactgcgag aagcgcgagg cggagtggcg
     9241 ggagcgcggc acctcgcgcc cgatcaccgt ggtcggcaac ccggtgctgc acaaggagtg
     9301 caaggacgtc accgacttcg gcgaggagtt ccagcagctc gtcgccgaca tgttcgccag
     9361 ccagcgcacc gccgagggcg tgggtctggc cgccaaccag atcggtgtcg acctgaaggt
     9421 cttcgtctac gactgccccg acgacgaggg tgtgcgccac gtcggcgtgg tctgcaaccc
     9481 caagctggtc gaactgcccg ccgagcggcg ccggctggac gacagcagcg agggctgcct
     9541 gtcggtgccc accgcgtacg cgccgctggc ccggcccgac tacgccgagg tgaccggtca
     9601 ggacgagaag ggcaacccga tccgggtacg cgggacgggg tacttcgcgc gctgcctcca
     9661 gcacgagacg gaccacctgt acggctacct gtacatcgac cgtctgtcga agcgcgagcg
     9721 taaggccgcg ctcaagcaga tggccgagaa cgagccgcgc taccccgtgg tcgccaacga
     9781 ctgaccgcct tcacggctcc cctcacatcc cgcgcacggc gcccgatccg gcacatcccg
     9841 gacgggcgcc gttcgtctgt gcgcatccaa aggtagtgaa agaagcaaat ccgttcccac
     9901 aacggtcagt tgtggtgctg aatggaggta cggggatacg cacggcgtac gcccggctcg
     9961 gggggcgggc gctcaactgg cggctgagag gggaatgttc gtgcatgctt tgtcacacgg
    10021 ctccacatcg acaccgacca ccatcgcagt tccaccggcg ctgtctcttc cggtgatcga
    10081 ggcggcgttt ccccggcgac tccacccgta ttggccgaag ctccagaggg agacccgggc
    10141 atggctgctc gaaaagcggc tcatgacccc ggagaaggtg gaggaatatg ccgacggcct
    10201 gtgctacacg gacctcatgg cgggctacta cctcggcgcg cccgacgagg tcctccaggc
    10261 gatagcggac tacagcgcct ggttcttcgt ctgggacgac cgtcacgatc gcgacatcgt
    10321 gcacggccgg cccgacgcct ggcggcggct gaaggacctg ctgcacagcg ccctcgaccg
    10381 ccccggtgac cacctgggtc accaggaccc cgtggtcgcg ggcctcgccg acagcgtgcg
    10441 gcggctccac gcattccttc cggacacctg gaacgcgcgg ttcgcgcgtc acttccacgc
    10501 cgtgatcgag gcgtacgacc gggagttcca caaccgcacc gaaggcgtcg tcccgaccgt
    10561 cgaggaatac ctcgaactgc gccgcctcac gttcgcgcac tggatctgga cggaccttct
    10621 ggaaccgagc gcggggtacg aactcccgga cgcggtgcgg aagaacccgg cctatcggaa
    10681 accggcgctg ctcagtcagg aattcgccgc ctggtacaac gacctctgtt cgctgcccaa
    10741 ggaaatcgcc gggaacgagg tgcacaatct cggcatcagt ctcgtcaccc acgagggaat
    10801 gaccctcgaa gaggcgatcg ctgacatacg gcgccgcgtc gaggaatgca tcagcgaatt
    10861 cctggacgcg gaacaggagg cattacggtt cgccgaccgg ctcgacgacg ggacggtggg
    10921 cggaaaggag acgagcgccg ccgtacgcgc ctgcgtcggc aacatgcgga actggttcag
    10981 ttccgtctac tggttccacc acgagtccgg ccggtaccgg gtcgacagct gggacgaccg
    11041 gtccacgccc ccgtacgtcg acaacgcaac ggaaggtgag aaatgaccgt cgagtccgta
    11101 cgcccggagg acaccgccgc gacggccgag ccgcccgtgg cgggcggtgc cgtcccgctc
    11161 ctcggtcacg gctggcgcct ggtgcgcgac ccgctggcct tcctgtccca gctgcgcgac
    11221 cacggtgacg tggtgcgcct gaaactgggt cccaagacgg tctacgccgt caccaccccc
    11281 gccctcaccg gagcggtggc gctcagcccg gactacatca tcgccgggcc cctgtgggag
    11341 tcgctggaga gcctgctcgg caaggagggc gtggccaccg ccaacggccc gctgcaccgc
    11401 cgccagcggc gcaccatcca gccggcgttc cggctcgacg cgatccccgc ctacggtccg
    11461 atcatggcgg aggaggccta cgcgctcgtg gagcgctggc gggacgcgga cggggtgctg
    11521 gacatcacgt acgagtcgtt ccgcgtggcc gtgcgggtcg ccgcccgctg cctgatgcgc
    11581 ggcggctaca tggacgccca cgccgaccgc atatgcgccg acctcaccac cctgttcgcg
    11641 gggatgtacc agcgcatggt ggtgccgctc ggaccgctct acaagattcc gcttccggcc
    11701 aatcgggaat tcaaccgcgc cctggccgat ttgcatgtcc tggtcgacga gatcgtggcc
    11761 gaccgacggg cgagcggtca aaagccggac gatttgctga cggctttgct ggaggcgaag
    11821 gacgacaatg gcgaccccat cggggaacag gagatccatg atcaggtcat cgccatcctg
    11881 acccccggcg cggaaaccgt cggttccacg atcatgtcgc tcctcctggt tctcaccgag
    11941 cacccggaac tcggcgacaa gatccgcgac gaggtgaaat ccgtggtcgg cgaccgcccg
    12001 gtcgcattcg aggacgtgcg gaagctgacg tacaccgcga atgtcgtcac ggagaccctg
    12061 cggctgtatc cggccgtctg gatattgacc cggcgcgcgg tcgccgacac ggaactcggc
    12121 ggttaccgca ttccgaaggg tgcggacctc atctacagcc cgttcgcggt ccagcgcgac
    12181 cggcggtcgt acgagcggaa cgaggacttc gacccggacc gctggctccc ggagcggtcg
    12241 aaggacgtgc ccaagtacgc gatgagcccg ttcagcgtgg gcaaccgcaa gtgccccagc
    12301 gaccacttct ccatggcgga gctcacgctc gtcaccgccg tggtcgccca cgcgtacggc
    12361 ttcgagcacg cgtcggactc cgatccccgg ccccgcatcg gcatcacgct gcggccccgc
    12421 cggctgatgc tgcgggcgct gccccgctga cgccccgccg accggcgcgc ggtcaggcgg
    12481 cctccgggcc cctgaacgcg cgccggtagg actgcggggt ggtccccacc gcgcgtacga
    12541 agtggtggcg cagcgcggcc gcgttgccga agccggcgcg gcccgcgatc gcgtccaccg
    12601 tctcgtccgt ccgctccagc agatgctggg cgagcagcac ccgctggcgc aggatccagc
    12661 ggtagggcgt ggtgccggtc tcctgctgga agcggcgggc gaaggtgcgc ggcgacatga
    12721 gggcgcgggc ggcgagctgc tcgacggtga cctcctcgtc gaggtgctgc tccatccaca
    12781 ccagcacccc ggcgaccgag tcgcccccgg gttccggcag cggacgttcg atgtactggg
    12841 cctgcccgcc gtcgcggtgc gggggcacca ccatccggcg ggcgatccgg ttggccacct
    12901 cagggccctg ttccttgcgc accaggtgca gacaggcgtc gatgcccgcg gcggtgcccg
    12961 ccgaggtgat caccgggtcc tcgtcgacgt agagcacgtc gggttcgacc gtcagatgcg
    13021 gatagcggcg gctcagctcc tccgcgtgct tccagtgcac cgcggcccgc cggccctcca
    13081 gcagcccggc ggcggccagc acgaacgccc cggagcacac gctcagcacc cgcgcgcccc
    13141 ggtccaccgc ccggcgcagc gcgtccagca tctcgggtgg gaactcccgg gaggtgtagg
    13201 aggcgccggc gggcacggtg atcaggtcgg ccgcgtccag ccggtccagg ccgtgctcgg
    13261 tctggagcgt gaaaccggcg ctggcgcgca ccgaggcccc ctccgcagag acgaccgcga
    13321 agtcgtacac cggcagcccg tcgtcgctgc ggtcgatgcc gaagacctcg cagaccacgc
    13381 cgagttcgaa cggattcacg ccgtcgagca ggacggccgc cacattccgg agcatggctc
    13441 cagtgtgcct cgccgttggc agtaaatcga gggtgcacga cagtcctgcc actcctcgta
    13501 aggagcgtcc ggcggcacag tggtgtccat gaacacgacg cagacagaag cactgatcgc
    13561 gatggtggcc gttctcggcc tgttcgtcct catggtcgcg cccgccgtga tcggcatcct
    13621 gcgcgaccgc cgcatcgacc ggcagatccg gcgggcccgg gccaccctgg tcaccgagcc
    13681 gcccggtatg ccggccgcgt cccggccgga gcaccgggcc gcctcccgcc gccacgcacg
    13741 cgcggcgtga gacggccccg gcgcccgggc cctagaagtc ctcgtccagg tcgaccgtgc
    13801 cctccacggc gacctggtac gcggacggac ggcgttcgaa gaagttggtc agctcctgca
    13861 cgccctgcag ctccatgaac gagaacgggt tctccgagcc gtacaccggc gcgaagccca
    13921 gccgcaccag acgctggtcg gcgacgcact ccaggtactg ccgcatcgac gcggtgttca
    13981 tgccgggcag cccgtccccg cacaggtcac gggcgaactg cagctccgcc tcgacggcct
    14041 cgcggagcat gtcggtgacc tgccgcccga gctcctcgtc gaacagttcc ggctcctcct
    14101 tgcgcacggt gtccaccacg tcgaaggcga agctcatgtg catcgtctcg tcgcggaaca
    14161 cccagttggt gccggtcgcc agcccgtgca gcagaccccg gctgcggaac cagtagacgt
    14221 aggcgaaggc gccgtagaag aacagccctt cgatgcaggc cgcgaagcag atcaggttca
    14281 gcaggaagcg gcgccggtcg gcccgcgact ccagccggtc gatcttctcc accgagtcca
    14341 tccaccggaa gcagaactcg gccttctccc ggatggacgg gatgttctcc acggccgcga
    14401 aggccgccgc ccggtcgtcc ggatcgggca ggtaggtgtc cagcagggtc aggtagaact
    14461 ggacgtgcac ggcctcctcg aacagctgcc gtgacaggta cagccgcgcc tcgggcgagt
    14521 tgatgtgctt gtacagcgtc agcaccaggt tgttcgccac gatcgagtcg ccggtggcga
    14581 agaacgccac gagccggccg atcagatgct gctcctcggg cgtcagcttc gccaggtcgg
    14641 cgacgtccga gtgcaggtcc acctcctcga catgccaggt gttcttgatc gcgtcccggt
    14701 agcgctcgta gaagtccggg tagcgcatgg ggcgcagggt cagctcgaag ccggggtcga
    14761 gcaggttctt ggtcgtgctg gtggtcactg gcaggcctcg caggattcgg ggttctcgag
    14821 ggagcaggcg acggcctcgg ggtcggccgg ctgctggacg gggacgggta cggcggcgcg
    14881 ggccgcgcgg gcgatccggg tcgccggacg ggaacgcagg tagtaggtgg tcttcagccc
    14941 ctgcttccag gcgtaggcgt acatcgagga gagcttcccg atggtcggcg tctccaggaa
    15001 caggttgagc gactgcgcct ggtccaggaa cggggtccgg gcggcggcca tgtcgatcag
    15061 gccgcgctgc gggatctccc acgccgtgcg gtacagccgc cgtacgtcct cggggatcca
    15121 cgcgaagtcc tgcaccgagc cgttcgcctc gcgcagcgcc tcacgggtgc gcgcgtccca
    15181 cacgcccagc cgcttgaggt cctccaccag gtacgagttg acctggagga actccccgga
    15241 cagcgtctcg cgcttgaaca ggttggacac ctgcggctcg atgcactcgt acacgcccgc
    15301 gatcgatgcg atggtcgcgg tgggcgcgat cgccagcagc agcgcgttgc gcaggcccgt
    15361 cgcggcgatc cgcgaccgca gtgcctccca gcgctccggc caggcgagct cgactccgta
    15421 gtggtcgggg tgcagcacgc cccgcgcggt gcgggtcttc tcccaggcgg gcagcggacc
    15481 gtgccgctcc gcgagaccgg cggacgtctc gtacgcggcg agcatgatgc gctcggcgat
    15541 ccgggtggac agcgccttcg cctcggggga gtcgaagggc acgcgcagcc ggaagaacac
    15601 gtcctgcagc cccatcacgc ccagacccac cgggcgccag cggctgttgg accgggacgc
    15661 ctccccggtc gggtagaagt tgatgtcgac cacccggtcc aggaacgtca cggcggtgcg
    15721 gaccgccgcg tccaggcgct cccagtccat gccgtccggg cccgcgaagg ccgcgaggtt
    15781 gaccgagccg aggttgcaga ccgccgtctc cccgtcgtcg gtgacctcca ggatctccgt
    15841 gcacaggttg gaggagtgga cgacgtgacc cggttcggcg gtctggttgg cggtgcggtt
    15901 ggcggtgtcc ttgaaggtca tccagccgtt gccggtctgc gcgagggtgc gcatcatccg
    15961 gccgtacagc tcgcgcgccg ggagcgtcct gcgggccagg cccttcgcct cggcggctcg
    16021 gtaggccgcg tcgaactcct cgccccacag gtcgaccagc tcgggcacgt cgacggggga
    16081 gaacagcgac catggggcgt ctgcgtcgac ccggcgcatg aactcgtccg ggacccagtg
    16141 cgccaggttc agattgtgcg tacggcgggc gtcctcaccg gtgttgtcgc gcagctccag
    16201 gaactcctcg acgtccgcgt gccaggtctc caggtagacc gcggcggcgc ccttgcgccg
    16261 gccgccctgg ttcacggcgg cgaccgaggc gtccagcgtc ttcaggaacg ggacgatgcc
    16321 gttggagtgc ccgttggtgc cgcggatcag cgaaccccgg gcgcggacgc gggagaagga
    16381 caggccgatg ccgccggcgt gcttcgacag gcgggcgacc tggtggtagc gctcgtagag
    16441 ggagtccagc tcgtccttgg gggagtccag gaggtagcag gacgacatct gcgggtggcg
    16501 ggtgccggag ttgaacagcg tgggggagga gggcaggtag tccagccggc tcatcagccc
    16561 gtacagcgcg gcgacgtcct ccagcgcccg ctcgctctcg tcctcggcga gcccgcaggc
    16621 cacccgcagc aggaagtgct ggggcgtctc gacgaccttg cgggtgaccg ggtggcgcag
    16681 caggtagcgg ctgtgcaggg tgcgcaggcc gaagtagccg aaccggtcgt cggcgtccgt
    16741 gtcgaccagc gcgtccagac gggccgcgtg gagccggacg aacgcggcgg tgcggtcgcc
    16801 gatcaggccc tcccggtgac cggcggccac cgagccggtg aacgaggtga cgccctgcga
    16861 ggcggcctcg gcgcggatgc cgagggtgag cagccgggcg gcgagccggg agtaggcggg
    16921 gtcctcggag atcagcccgg ccgccgcctc ggtggccagg tcccgcagct ccgcctcgtc
    16981 ggcggaggcg gaccggccgc gcagcgcggc cgcggccacc cggccggcgt cggcgtcggg
    17041 caggtcggcg gtcagcccgc agctccgcct cgtcggcgga ggcggaccgg ccgcgcagcg
    17101 cggccgcggc cacccggccg gcgtcggcgt cgggcaggtc ggcggtcagc tgggtcaggg
    17161 tccgcagcag cgcggccccg gggccgtcgc tgtcctcggt cacgcgggtc gctgaagccg
    17221 gatcggctgg cgcgatggtc acgtgtggct ctccctcgct cggcacgggg gcctcgaaga
    17281 gcgcaggggg cagcacacga acgcacgcgg cgtcgcgtcc accggcccat tccgcgaggc
    17341 ccggacgtca gggcacccgg accggaaggg ccgggcgcac tgtcggcagg tcctcggact
    17401 gactcccgtg cgcgcccgtg ggcaggcatg ggtacaccgt tgcgggacag ttccggattc
    17461 gcaccggatt cccctgcggc gacagcgagc atgagcatac atcttgtgcc gggtgtcgcc
    17521 gacggaccca tatgttgtgt cgcgctgggg ttatggtggg gtcggacgga agggctgcgc
    17581 ccggccgtca gagcgtcagt tcgtagacca gcagcatgat gtcgtcgagc tccggcagcg
    17641 ggttccagtc ccgcccgggg gcccgcgtga agcccagccg ctcgtacacc cggtgcgcgg
    17701 agtgcatcgt gcgctgcgtg gacagcacca tgcgggtgcg gccgagcgcc cgcgcccggt
    17761 cgacgcaggc gcgcaccagg gcctcaccgg cgccccggcc gcggtgggcg ggggagacgg
    17821 ccagcatccg tatctccgcc tcgccgggct ccgcgatgtc ggccatgggc ccggggccgg
    17881 gcacgaaggt caccccgccc agcagcgcgc cgtccgccac ggcgaccagc acctcggcgg
    17941 ccgccgcccg cttgcccacg tcccgcagct cgtccaggta ggagtcggac tccccgaagt
    18001 ccagcagccc gtcgccgaga taggcctgag cggtgatctc accgaggtcc gcgtgctcgc
    18061 cgggcgtcgc cggccggatg acgatgtcca tgcgggggag tctgccgcac gggcacgaca
    18121 gcgggccgcc ggttttccac cggcggcccg ctgccctgtg cgtgaacggc gtcagtgctt
    18181 gctgtccgcc gtggccggcg ggagctccac ctgcacgccc gggtcgccgg cgtccgccgt
    18241 gtagtcgcgc ggctcggtct cgtcgacgcc gtccggcgcc ttgaccgccc gcatgacgaa
    18301 ggtcaggacg accgtgacca gcacgttgat cacgaaggcg gtgagaccga tgtagccgat
    18361 ctccccgatg cccgggatct ccttggcgga gccgccgaag tgcttctgcg tcggcgacgc
    18421 caccccgtac gcggcgaccg tgccgtagat catgccgacc gcccagccgc cgatcagcgc
    18481 ccagcggtgg aaccagcggg tgaacaggcc gcccaccagc gccgggaagg tctgcaggat
    18541 ccagatgccg cccagcagct ggaagttgat cgcgacggtc ttgtccatgg tcaggacgaa
    18601 gaccagcgcg cccaccttca ccagcaggga cacgatcttg gagaccgcgg tctcctgctt
    18661 gggcgtcgcg tccggcttga tgaagtcctt gtagatgttg cgggtgaaca ggttcgccgc
    18721 cgcgatcgac atgatcgccg ccggcaccag cgcgccgatg ccgatcgccg cgaaggccac
    18781 cccggcgaac cagtccggga acatgttttc gaacagctgc gggatggcca gctggccgtt
    18841 ctgcaccttc accccggccg cgatcgccat gaacccgagc agcgccagca ggcccagcat
    18901 cagcgagtac agcggcagga tcgtggtgtt gcggcggatc acctcacggc tgcgcgagga
    18961 cagcgtcgcg gtgatcgagt gcgggtacat gaacagcgcg agcgccgacc ccagcgccag
    19021 cgtggcgtac gtccactggc ccgcctcgcc cggcaccagg gcgccgcgcg gggcaccggt
    19081 ggccgggttg gtctcgctgt acgcctcctg cgcggaggcg aagatctcgt cgaacccgcc
    19141 cagtttgatc gggatgtaga tgatcgccac cgcgatcacg atgtagatca gcgtgtcctt
    19201 gacgaacgcg atcagcgcgg gcgcccgcag ccccgacgag taggtgtacg cggccagcac
    19261 accgaaggcg aggagcagcg gcatgtcctt gatgaaccag ttggtgttct cgccgccgcc
    19321 gacgcccatc acgtccagca cggcctggat gccgaccagt tgcagcgcga tgtacggcat
    19381 cgtcgccagg atgccggtga ccgcgacggc cagcgacagc cccttcgagc cgaaccgccc
    19441 gcgcacgaag tcggacgtcg tcacatagcc gtgcttgtgc gacaccgacc acagccgggg
    19501 caggaaggtg aagatcagcg gatacacgag gatcgtgtac ggcaccgcga agaagccggc
    19561 cgcgcccgcc gcgtagatcg ccgccgggac ggccacgaag gtgtacgcgg tgtacaggtc
    19621 gccgccgagc aggaaccagg tgacccaggt gccgaacgac cgcccgccca ggccccattc
    19681 gtcgagagtg tgctcgttgg cggccttgcg ccagcgtgcg gccaggaagc ccatcacggt
    19741 gacgagcacg aagaagaaga tgaagacggc gagtgccacg ccgttcacgc cgtcgttcac
    19801 tgctcggcac cacccttcgc ggcggagcgg gcgcgctggt cacgctgcca gagcttgtac
    19861 gcgatcatcg tgagcgcggt cgagatcagc acccacagca tctggtacca gtagaagaac
    19921 gggatgccga tgaacaccgg gtcggtcttg gcgtaggacc cgacccacag catggcgacg
    19981 aatggtgcga gcagacagag gccgatgacg acgcgcatgg gcgtcaccac cggccctggt
    20041 gttgtttgcg gggtttgcga catcagacgg ctcccgtccc ctcactgatc gccgacgttg
    20101 gctcgcggca atgtaggtga gggcgcgggg cggtcgtaac ccctcgtaag aggggcggta
    20161 tgcagcagca gcgcaaccgc aaggcaacag caacgaaaat cctgtcaacc gcccggtctg
    20221 tcgggttttg cggtgacgtc ggcggctgtc cgtcagtcct gggggcgctt gaggcgcgcg
    20281 acgaacttgt accggtcgcc ccggtacacc gaccgcaccc actccacggg ctgcccgccc
    20341 cggtccagcg agtgccggga cagcatcagc atcggcaggc ccacgtcggt gccgagcagg
    20401 cccgcctcgc gcggcgtggc cagggacgtc tcgatggtct cctcggcctc cgcgagatgg
    20461 acgtcgtaca cctcggcgag ggccgtgtag agagacgtgt acttggtcag gctgcggcgc
    20521 agcgccggga agcgcttggc gctgaggtgg gtggtctcga tggccatggg ctcgccgttg
    20581 gccatgcgca gccgctcgat gcgcagcacg cggccgccgg cggtgatgtc gagcagcccg
    20641 gccagccggt cgtcggccgt gatgtacccg aggtcgagga gctgcgaggt cggctccagg
    20701 ccctgcgcgc gcatgtcctc ggtgtacgag gtgagctgga gcgcctggga caccttgggc
    20761 ttggcgacga aggtgccctt gccctggatg cgctccagac gtccctcgac caccagttcc
    20821 tggagcgcct ggcgcacggt ggtgcgggag gtgtcgaact cggccgccag cgtgcgctcg
    20881 ggcgggaccg gggtgccggg gggcgccgtc tcggtcatgt cgagcagatg cttcttcagc
    20941 cggtagtact taggcacgcg tgccgtacgg accgcggtcc caccctcgtt ctccgtactg
    21001 ctgacgtcgg tgctcatgct ctgccttccc ggctccggct gccgaagcgg ccgacagacc
    21061 gtcggccacg gctgacatcg tggcac
//
