LOCUS       NZ_KL503830            24529 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Streptomyces griseorubens strain JSD-1 scaffold1, whole genome
            shotgun sequence.
ACCESSION   NZ_KL503830
VERSION     NZ_KL503830.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces griseorubens
  ORGANISM  Streptomyces griseorubens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces althioticus group.
REFERENCE   1  (bases 1 to 7563100)
  AUTHORS   Feng,H., Zhi,Y., Sun,Y., Wei,X., Luo,Y. and Zhou,P.
  TITLE     Draft Genome Sequence of a Novel Streptomyces griseorubens Strain,
            JSD-1, Active in Carbon and Nitrogen Recycling
  JOURNAL   Genome Announc 2 (4), e00650-14 (2014)
   PUBMED   24994798
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7563100)
  AUTHORS   Feng,H., Sun,Y., Zhi,Y., Mao,L., Luo,Y., Wei,X. and Zhou,P.
  CONSRTM   Shanghai Jiao Tong University
  TITLE     Draft genome sequence of the novel Streptomyces griseorubens JSD-1
            playing a role in carbon and nitrogen cycle
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7563100)
  AUTHORS   Feng,H., Sun,Y., Zhi,Y., Mao,L., Luo,Y., Wei,X. and Zhou,P.
  CONSRTM   Shanghai Jiao Tong University
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2014) School of Agriculture and Biology, Shanghai
            Jiao Tong University, Shanghai Jiao Tong University, Shanghai,
            China, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2013-12-24
            Genome Coverage                   :: 246x
            Sequencing Technology             :: Illumina Miseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000709915.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:19:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,036
            CDSs (total)                      :: 6,948
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 329
            CDSs (without protein)            :: 328
            Pseudo Genes (ambiguous residues) :: 0 of 329
            Pseudo Genes (frameshifted)       :: 72 of 329
            Pseudo Genes (incomplete)         :: 272 of 329
            Pseudo Genes (internal stop)      :: 8 of 329
            Pseudo Genes (multiple problems)  :: 23 of 329
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:40:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 321804
            Orig. end                         :: 346333
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KL503830.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24529
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="4"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24529
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24529
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14529](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14529
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            99..1049
                     /locus_tag="DJ64_RS01295"
                     /old_locus_tag="DJ64_27025"
     CDS             99..1049
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523024.1"
                     /locus_tag="DJ64_RS01295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27025"
                     /product="polysaccharide deacetylase"
                     /protein_id="WP_037637671.1"
                     /transl_table=11
                     /translation="MPAAEPGLPEESWRWTEPTWRGHVDAVRAGRRLVPDRWPGGARAA
                     VALSFDSDHETIPLRDGETSPGRLAQGEYGARVGAPRILRLLAQHGVPATFFMPAVSAL
                     LHPEEARAYTEDGHELAVHGWIHERNTLLGREDERELTARALDTLDALTGRRPVGIRTP
                     SWDFSGSTLATMLDLGFGYDSSLMADDDPYEIVAEGRPTGLVEIPVDWIRDDAPYFTMD
                     RFGAVRPHSRPRDVGEIWRDEFDAAYREGGVFQLTLHPHVIGHRSRLVVLRELLDHIKA
                     HHDVWFATHAQLADTVRTVLDGTAGARPVPSERTP"
     gene            1046..2371
                     /locus_tag="DJ64_RS01300"
                     /old_locus_tag="DJ64_27030"
     CDS             1046..2371
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523025.1"
                     /locus_tag="DJ64_RS01300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27030"
                     /product="MFS transporter"
                     /protein_id="WP_037637673.1"
                     /transl_table=11
                     /translation="MNLKSDLSPGSPAAGGASEPQKLNAKQRKAIVAGTIGNTVEWVDW
                     ALYSIFAKIIADEFFPKGNGAVALLSTLAVFAVGFVMRPVGAAVLGAYADRHGRKKGMT
                     LTVALMAGAGFAIAVTPGYEHIGVLSPLLLLVARLVQGFSAGGEFGSSSAFLVESAARG
                     RRAFAGSWQQVSVAGGVLIASLLGTLTTSALSDEALHSWGWRVAFVFGGLLGLVGLWLR
                     VSVEDTESFARSQDSGRTRTNPVKAMFVEHPAATLRVVGITIAGTLTYYIWVNYLPTYA
                     NLTTGIPLKTALLSQTLCLVVFVIALPFAGLLSDRIGRRPTMAAFAGGFVVLAWPLLHL
                     LGDSFWSLFPVQLVGMLLILGYSSNCAVIMAEQFPAEVRATGIALPYALAVAVFGGTAP
                     YVTTWMHESGHSGLLWIYVSAASLISLVVYLTMPETKDKDFT"
     gene            2368..3201
                     /locus_tag="DJ64_RS01305"
                     /old_locus_tag="DJ64_27035"
     CDS             2368..3201
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-164). E-value: 1.3e-13. Score:
                     43.2. Matches aSDomain:
                     nrpspksdomains_DJ64_RS01305_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523026.1"
                     /locus_tag="DJ64_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27035"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_037637676.1"
                     /sec_met_domain="adh_short (E-value: 1.5e-32, bitscore:
                     111.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-30, bitscore:
                     105.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHVLVTGAAGGIGSAIAEAFAARAAFLTLSDRDVDALRATAARI
                     EGSTAIRAADLTDPDAPSDLVEQIWAAHGPVDVLVNAAGVYPSLDMADVDAESWDRLFA
                     VNLRAPVLTTAALARLAAAAGRPASVVNISSGSALRSRPGGGPYASSKAALEMATRAAA
                     LELGALGIRVNAVSPGFVLVDSDVNPVSAEYARSIDVNPLGRPGTPEDVARAVCWLAGP
                     EASWITGETVRVDGGSSTGALHLPRIWQADGTRATRTTHAEAPVGAGTTTEEATR"
     aSDomain        2377..2859
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DJ64_RS01305_PKS_KR.1"
                     /evalue="1.30E-13"
                     /label="DJ64_RS01305_PKS_KR.1"
                     /locus_tag="DJ64_RS01305"
                     /protein_end="164"
                     /protein_start="3"
                     /score="43.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VLVTGAAGGIGSAIAEAFAARAAFLTLSDRDVDALRATAARIEGS
                     TAIRAADLTDPDAPSDLVEQIWAAHGPVDVLVNAAGVYPSLDMADVDAESWDRLFAVNL
                     RAPVLTTAALARLAAAAGRPASVVNISSGSALRSRPGGGPYASSKAALEMATRAAAL"
     CDS_motif       2380..2445
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DJ64_RS01305_0001"
                     /evalue="6.20E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="DJ64_RS01305"
                     /protein_end="26"
                     /protein_start="4"
                     /score="18.9"
                     /tool="antismash"
                     /translation="LVTGAAGGIGSAIAEAFAARAA"
     gene            3198..5408
                     /locus_tag="DJ64_RS01310"
                     /old_locus_tag="DJ64_27040"
     CDS             3198..5408
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523027.1"
                     /locus_tag="DJ64_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27040"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_037637678.1"
                     /transl_table=11
                     /translation="MSDITQDAAAYTVVGGGAIGGTLAFALARAGHPVTVVDADPAHVE
                     AIRTHGLVLARGDRRTSVPVRAVTPDAFDGRLGRVLLAVKAQATRGAVEWIAPRLEPDG
                     YVVSVQNGFNEDLIAEYVGIGRTVAAFVNIFADVVEPGVIRDGGAGALVIGEPKGAPVG
                     ERVRSLVADLQSWGPARASDNVEGYLWAKAGFGAMLAATALADAPMADLIDRHRPAMAA
                     LTAEVFAVADRRGVTLQAFDAFDPEPFRQGADAGAREAAFDRLTAWLRTQSKDRSGIWR
                     DLAVRHRPVEVTTHYRDVIAYATELGLPSTLLGTVMDGLRELEGAPETMSEGRLDALDR
                     LTGPNLDDWDPGVRVRRWLEEHREEMVADLAAYTARGSASDDLDALDACLAWLRGWLDE
                     RLGAAESEEILGREDAGDVLVRRYPARDATTADARPVLLLGHYDTVWPTGTLESWPFRR
                     DGDTVTGPGVFDMKAGLVQAVWALRALDALGLPRPAVTLMLNGDEETGSLASRDAIVET
                     GRDCRLAMVFEAAVDGAIKTARKGVGLFTLTVTGSEAHAGLDPTAGASAVDELAYQILR
                     LAELRDLEAGTSLNVGVIEGGTRGNVTAGRASAHLDVRVASAAEQDRITRALADLRPVD
                     PGTRLEVTGDWNRPVFERGEQVAWAAGLAKDAARRLGHDLAEAAVGGASDGNFLAAAGV
                     PVLDGVGAVGHGAHARTECTSVAGMVFRSALTGGVLVRLAGE"
     gene            complement(5778..7841)
                     /locus_tag="DJ64_RS01315"
                     /old_locus_tag="DJ64_27045"
     CDS             complement(5778..7841)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125451.1"
                     /locus_tag="DJ64_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27045"
                     /product="hypothetical protein"
                     /protein_id="WP_245657242.1"
                     /transl_table=11
                     /translation="MNSPRPSSDLAAVTTWWNGLACNGFFVLPPPTRRRFTQADGHEEA
                     ALLLAARGGRGGTATDTTRPASFAYWHWDAHRNAFDRSGTLTGELLLHWGGDHATVAAG
                     LGEGPPGFGIVDGGPRSAFRLDRITHRDDDGLPDPSDPDGVRQFLSMLGEPVDRAAPRL
                     TYGPLSPAEAAWLHARLDEAPDVSAAARFAIPLEQRDELTADETERLLHAWQAEYAGRL
                     TEWNAGSAVLHALLRHGHAAAWDIVAVYGLRAYGVLSDVPTAQGLRVVREAALAGDRGA
                     LRAWLSLHRTLHEPDAVRAASALAAELTAHGASESSLRGLYEALIGAAVTDRRRDTGAG
                     PGSVDLHAGLAAVRFSTDERLPHALRVLAAAAARDRAELVREEALRPGSAVLTGTEQSE
                     ALAALDRYEAARDALSSATGPDLDTYEGALCAVWHHYRTLTDADAHWLRERVADPGTGL
                     QGLGFCLELLHSHGLAGRHEIEALLPHRLKDLTKKYETTYTEWRHPLVTLTCLALDLDH
                     PEAGRLVSWWNRARPVWKDKLRLLTHLGAPDETKAAELWDFVTSPAHDVGQLMTYVLVR
                     ARLDGEHPLLVADRLIGAPGIRDRVLHRVLLGVADPAQPLWHYAVKSSSRSWWQRAREV
                     AEDTRLSSEGRAIGLRAARDHALIRYSDRLKPPPSEAERAQALAWLTGHGES"
     gene            7970..8758
                     /locus_tag="DJ64_RS01320"
                     /old_locus_tag="DJ64_27050"
     CDS             7970..8758
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004927657.1"
                     /locus_tag="DJ64_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27050"
                     /product="hypothetical protein"
                     /protein_id="WP_245657243.1"
                     /transl_table=11
                     /translation="MARGTVRGHRVVGAGLVLLLASAGCGSPAGDSGDGGATAAPPVRD
                     KGPVCVGEAPADGVRVLRGGGFRLPGGTGVQYAGASADGSSRTATLREGARYEEGQREW
                     KVAVGARVPLAGHAYTVRQVCSYRVVLEAASARDASALAEAPASMTSTGGEADAGLCFT
                     TNRAVLKAAADGFPAEGESLSLVGNGGVRRFPTGLSLTVSYLDAEAGTAGIAANCAAVP
                     VAAYEELRVGDPLELGGVLFEVTDVTEAVVRLTRPAAPRP"
     gene            complement(8768..9382)
                     /locus_tag="DJ64_RS34795"
     CDS             complement(8768..9382)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023580.4"
                     /locus_tag="DJ64_RS34795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3592 domain-containing protein"
                     /protein_id="WP_157842166.1"
                     /transl_table=11
                     /translation="MQKKEPLPVGKKKKRRPRRENWTRPPLSAERRAAEEEWRRSRAAP
                     NRPPLPQKRLIAALFGLALVTLTAFLMFLLPGRSLVNDLRSRGISVVAEVTAASKNKYG
                     DAGNVKVRFDGPDGTVETELHDWGGKRPEGLRAGAAVPVTYDPREPTRVLTTRWVEDPP
                     TATLPMLVTAVLTPLLLSGAVFLVVRRRRLLKAGEQADPTA"
     gene            9442..>9549
                     /locus_tag="DJ64_RS37685"
                     /pseudo=""
     CDS             9442..>9549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015506827.1"
                     /locus_tag="DJ64_RS37685"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="diadenosine tetraphosphate hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTDDWRKDRIGAAPRGDNPTVTRRPDAGFAAIGDVR"
     gene            9749..9910
                     /gene="lanA"
                     /locus_tag="DJ64_RS34550"
     CDS             9749..9910
                     /codon_start=1
                     /gene="lanA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) strep_PEQAXS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978597.1"
                     /locus_tag="DJ64_RS34550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SCO0268 family class II lanthipeptide"
                     /protein_id="WP_058915350.1"
                     /sec_met_domain="strep_PEQAXS (E-value: 2.9e-40, bitscore:
                     134.7, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTEIVLSQDAPELDLDLDLRVSDLPEQAESFGQGTYTSPSSYAI
                     GTRCPVCC"
     CDS_motif       9749..9835
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRTEIVLSQDAPELDLDLDLRVSDLPEQA"
                     /locus_tag="DJ64_RS34550_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9836..9910
                     /prepeptide="core"
                     /locus_tag="DJ64_RS34550_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-8.70"
                     /molecular_weight="2388.6"
                     /monoisotopic_mass="2387.1"
                     /core_sequence="ESFGQGTYTSPSSYAIGTRCPVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRTEIVLSQDAPELDLDLDLRVSDLPEQA"
                     /leader_location="[9748:9835](+)"
                     /alternative_weights="2406.6"
                     /alternative_weights="2424.7"
                     /alternative_weights="2442.7"
                     /alternative_weights="2460.7"
     gene            10001..13156
                     /locus_tag="DJ64_RS01330"
                     /old_locus_tag="DJ64_27070"
     CDS             10001..13156
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978596.1"
                     /locus_tag="DJ64_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27070"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_037637681.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.5e-171,
                     bitscore: 568.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.5e-15,
                     bitscore: 55.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.8e-28, bitscore:
                     97.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAECEAGQASAAFEVRDPVLVRMASRPRGTDLEGVDAADPVPGA
                     RRLAADPVLGQAVRVASGSLAQGLDRLTGDEGVAALGRKRTLSAARTLTRYARRAAARP
                     TPFGLFAGVGRARFGSAAKAEPGAGEVAVRLDGAWLRRRVMAWLAEPSVRRRVDVVLND
                     LCFVRDGRLCLRTGGQERSVRDNALVGAVRDRTRTLVGYGDLLDTLTRRFPSLDAERLD
                     GQLAELVRRGFLLTSLTPHRIDTALLDGIEAVLDEALPDDARALRDIRAACARHERDSP
                     GAGGESWHRLLDEVRRLDVPDTDGDAQARPPVHVDLHRRGEFVLPETVGREVCRYAGAI
                     WSITPEWTTLAHMRDYRDRFIERYGTACAVPLGELADPHRGLGLPPEYGAEPTYARTGP
                     GDEVDGPRRAFVGELIQEAVLSGGDLVLTDEVVRRLADVARHDPEAAPPRGLELCFQVL
                     ADSTAALDRGDFRLLGSPHIGAWAAGATAGRFAEAAGLTADLTRLATETSGDPDGDVIA
                     AQVELLPREPRGLNIVQVPRLLPYRIPVGVPDDRDDPRCLDWRTLLVAAGSDGLRLLHP
                     ESGRPVRPVLPHMLALDAQAPPVARFLMDLATARPRVWSGWDWAGHDTLPYLPRVRYGR
                     VVVMPKRWLPGRRLRDAARAKGAEVWEEGLDAWRRRLTVPDRLHIARNDQMYPVDLRDR
                     WDRELLRSELTALHPQFVLYEDLTTDGAGLGWNGGHSTEIVVPLAGARPSGGATGTGSR
                     GQARTAPPVRLAPTRFHLPGEDWLFAKWYAEPSAHEALLADHLPAVLGEIEDDVDRWFF
                     VRYQDPDPHLRLRFHGDVEALNGRVLPALSRASRVLVESGALRSMTLDTYRPESDRYGG
                     EALQEAAERLFRTDSLSAVVHLRAARGAARGLPADVLAGLGHAVLLESLGDWDWCGWVD
                     RMFTKSEEHEVYQRQRALADRLITPGNVVASAVEALGAPALRSLWADSDEPRAYGRAVL
                     SAPEADRDEALLSLLHMRHNRHFGIDRSAEARGYAVLRGAVRSHLGRQRHRGDHGNGNG
                     SGR"
     aSDomain        10475..10723
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DJ64_RS01330_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="1.00E-17"
                     /identifier="RREFam001.1"
                     /label="DJ64_RS01330"
                     /locus_tag="DJ64_RS01330"
                     /protein_end="241"
                     /protein_start="158"
                     /score="55.6"
                     /tool="antismash"
                     /translation="VVLNDLCFVRDGRLCLRTGGQERSVRDNALVGAVRDRTRTLVGYG
                     DLLDTLTRRFPSLDAERLDGQLAELVRRGFLLTSLTPH"
     gene            13153..14529
                     /locus_tag="DJ64_RS01335"
                     /old_locus_tag="DJ64_27075"
     CDS             13153..14529
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523032.1"
                     /locus_tag="DJ64_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27075"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_037637683.1"
                     /sec_met_domain="LANC_like (E-value: 1.4e-59, bitscore:
                     200.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGAADVSAKGGEARERADGAATRGLRERAGAVSAAILERLADPA
                     ATVAATRIPAEAADDGVAEPVWAELTLGSGSPGLALAFAGAARDPERQVPRAHAYLTAG
                     TRAVSGGPGAASGIFKGPGALAFAVLVAHRTTGGYVSALGRFDAYQRDLVRTVLPPVED
                     RPLSTIGHYEVVRGLTGVGRYLLARAETCEEPLTAVLDHLVRLSVGTVEHQGARVPRWW
                     ALDAPRTGSEEAFPGGHLNLGLSHGVAGPLALMALAWEQGVRVPGQQEAMEATAGLLRA
                     WAVTDRHGVFWPGHLSFAEWRRGPAAYDGRAKWPAWCYGAPGVSRALQLAGRALGRSDL
                     SDLARASVDRLLALPRSDWGINDHALCHGWAGALHQLGRLDEEWRDPRLARLRDDIASE
                     LVTAFDPALPFGLRFTMTKVPFGSDVSGYLDGAAGVALALDSYAVDGTPADWDMPLLLA
                     "
     gene            14649..15791
                     /locus_tag="DJ64_RS01340"
                     /old_locus_tag="DJ64_27080"
     CDS             14649..15791
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473846.1"
                     /locus_tag="DJ64_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27080"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_078492735.1"
                     /transl_table=11
                     /translation="MSTAAAAVAGTAVPAAAATARSPSRSLQRDADALRDAGVTGVAVR
                     LDTPHGTVTARSGVSDLRSRGPVPEGGYLRLGSTTKTFVATVLLRLVGERRVTLDQTVD
                     DLLPGVVQGAGNDGRTITVRHLLRHTSGLPDYVPDVFPEQSAETYFARRWRAYEAEELV
                     RLAVRHRPAFPAGTGWAYSNTNYVLAGLIIERITGRGWEREVADRILRPLGLRHTDNPG
                     TRPFLPHPHTSNYQQFTEGGPLVDTTLPYRPFDSGADGSMTGTARDLNRFFSALAGGRL
                     LAPAELNAMRDTVEVPPGNGHPVGARAGLGLFHTPLSGGGGCLGHSGSGFGYVVETATT
                     LDGRRTVTVSAHSRSADPEQAARQETALRDLIDHALSRGD"
     gene            15863..16273
                     /locus_tag="DJ64_RS01345"
                     /old_locus_tag="DJ64_27085"
     CDS             15863..16273
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523034.1"
                     /locus_tag="DJ64_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27085"
                     /product="RidA family protein"
                     /protein_id="WP_037643554.1"
                     /transl_table=11
                     /translation="MTAEITRINPPHLHATPGYHHITVVEAGRTAYLAGQCPLDASGKL
                     VGEGDLDAQIDQVAANALAALNAVGAGPEHVVRSVIYVVSDDVPVLGSAWRRLTSSVVG
                     PAFTTASTLLGVARLGFSGQLVEVDLTAALPH"
     misc_feature    15875..15889
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(16338..16802)
                     /locus_tag="DJ64_RS01350"
                     /old_locus_tag="DJ64_27090"
     CDS             complement(16338..16802)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700030.1"
                     /locus_tag="DJ64_RS01350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27090"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_037637685.1"
                     /transl_table=11
                     /translation="MRAVKINDIVIRRAAGSDAAEVAEVWLRSFTAALPGVRRAHTDDE
                     VRTWIREVVVPGQETWVAVADGSVVAMMVREGNDLDQLYVDPAWQGRGIGGRLVDVAKE
                     RSPSGLTLWTFQVNEAARRFYERHGFVARERTDGQRNEEREPDVRYEWRP"
     gene            <16917..17087
                     /locus_tag="DJ64_RS34805"
                     /pseudo=""
     CDS             <16917..17087
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575745.1"
                     /locus_tag="DJ64_RS34805"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="GY"
     gene            complement(17121..17678)
                     /locus_tag="DJ64_RS01360"
                     /old_locus_tag="DJ64_27100"
     CDS             complement(17121..17678)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523039.1"
                     /locus_tag="DJ64_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27100"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_037637687.1"
                     /transl_table=11
                     /translation="MLQTGSSVSTRESIHKAATRLFRSRGYSRTTVRQIAAEAGTDPAL
                     VIRHFKSKELLFLETMHLTLDDEPLLDVPLEHLGEGLAELLLDLGGSARGVFLALVHGS
                     NEPHIHDRLRDTHEHLFVEPLRRRLDGPDADVRARTAAAVAGGLLYALWVAGDQGLLRM
                     DRAELVSRYGALLQDVLTPRTS"
     gene            17944..18822
                     /locus_tag="DJ64_RS01365"
                     /old_locus_tag="DJ64_27105"
     CDS             17944..18822
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971632.1"
                     /locus_tag="DJ64_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27105"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_033274301.1"
                     /transl_table=11
                     /translation="MQKHVSRRNVMATSFALAGALTLSLTAGGTAQASDPLRYVALGDS
                     YSAGSGVLPVDTSNLLCLRSTANYPHVIADRTGARLKDVTCGAAQTKDFTSSQYLGVPP
                     QVNALSADTDLVTLTIGGNDNGTFINAITSCGSAGLLTAGKGSPCKDKYGSKFADEIRN
                     NTYPALKNALNAVRAKAPNARVAVLGYPWITPEKADPSCYLKLPIASGDVPYLRDVQTH
                     LNAAVERASEETGATFVDFAEVSDGHDACTPLGTRWIEPLLFGTSLVPVHPNALGERRM
                     AEHTMEVLGLK"
     gene            complement(18947..19342)
                     /locus_tag="DJ64_RS01370"
                     /old_locus_tag="DJ64_27110"
     CDS             complement(18947..19342)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020392461.1"
                     /locus_tag="DJ64_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27110"
                     /product="RidA family protein"
                     /protein_id="WP_033274302.1"
                     /transl_table=11
                     /translation="MERNAVNPVSWSVERGFNQGEVVSGHSRTLFISGQTAMGEDGKPE
                     HDGDMAAQLALSVDNVEAVLAEAGMSLANLVRLNVYTTDVDLLFRHYGVLAGRLGAAGV
                     APTTTMLGVTRLAIPGQMVELEGTAVA"
     gene            19458..20441
                     /locus_tag="DJ64_RS01375"
                     /old_locus_tag="DJ64_27115"
     CDS             19458..20441
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018385380.1"
                     /locus_tag="DJ64_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27115"
                     /product="WYL domain-containing protein"
                     /protein_id="WP_037637690.1"
                     /transl_table=11
                     /translation="MRADRLVSLVLLLRQRGRMTAEALARELEVSTRTVLRDMEALSSA
                     GVPVYAERGRHGGFALLPDFRTALTGLTHDEALALLVAGSRRGAQLFGLGSALASAVLK
                     VVDALPDGLRETAAGAAQRLLVDPETDLLARPVAPEEVPDAVATQVRRAVFGRHRLRIH
                     YAAVNQLPRWRTVDPIGIVTVKDQGYLLARRGSEDRTYRLSRVLAAEQLDEPARRADSV
                     DLGRAWREREVRFRTGGDTTEVLVRADPARRERLAATALAVTGEGTDAEGRLRMTVVFQ
                     DARHAEWALWEHAPGAEVLAPEWLRTRLGERAREVARLYGDASPEP"
     gene            20485..21513
                     /locus_tag="DJ64_RS01380"
                     /old_locus_tag="DJ64_27120"
     CDS             20485..21513
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964313.1"
                     /locus_tag="DJ64_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27120"
                     /product="S66 peptidase family protein"
                     /protein_id="WP_037637692.1"
                     /transl_table=11
                     /translation="MTVRYPSPLRPGDRVGVTSPSSGVPEALRARLEVALGDVRARGYE
                     VVVGRCMDGSGHVSASAAERADELMSMLTDPTVKAIVPPWGGETAIDLMPLLDWDRLRD
                     VEPTWVVGYSDMSTLITPLTLLTGTATLHGNNLMDTPYRVTEGLVSWFDVVAAPPGRSF
                     TQTPPGRHRTVGFDDFAVFPDVREYTLDAEGGWTRLDGEGDVEAEGRLIGGCVETLCNL
                     AGTPYLDVSAFHRDRAPEGLLVYVEVCDSDAFTVCRHLHGMKLAGFFEGANAVLVGRTG
                     APDSPSLTQHEAVLDALGSLGVPIVADVECGHVPPYMPIVNGAYGRVVHTTGRSALTQT
                     LR"
     gene            21546..22607
                     /locus_tag="DJ64_RS01385"
                     /old_locus_tag="DJ64_27125"
     CDS             21546..22607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700031.1"
                     /locus_tag="DJ64_RS01385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27125"
                     /product="hypothetical protein"
                     /protein_id="WP_051747773.1"
                     /transl_table=11
                     /translation="MSRGARLAAHGAVSASLARHSDRELRELLNAGRPLGSGIGGERVL
                     LDVDGTPVFVKRVRLTDPERRPENLYSTRNLFELPLFCHYGVGPIGGPGFGAWRELAVH
                     RMTTDWVVAGRYEGFPLLHHWRVLPDGGRPLPEELADVERAVAYWGGGAEVRHRIEALQ
                     RSSASVLLFLEYLPWNLHDWLGERMAAGEEAAERACAMVDDELRAGIAFMNANGVLHFD
                     AHFENILTDGRRLFFSDFGLAFSSRFDLARAEAEFFEEHRVYDRCYAVTHLVNWLTVAL
                     LGHEPEERAAFVRACAEGARPTRMPASIADVVARYAPVAVVMGDFRHQFRTVSRTAPFP
                     FTAIRQRLEKCDQ"
     gene            22624..23160
                     /locus_tag="DJ64_RS01390"
                     /old_locus_tag="DJ64_27130"
     CDS             22624..23160
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999517.1"
                     /locus_tag="DJ64_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27130"
                     /product="hypothetical protein"
                     /protein_id="WP_037637696.1"
                     /transl_table=11
                     /translation="MDPVVPTPVADQLFGQVQIELDHEGGTLRVSGEGLPTVEIRRSPD
                     TEVATHVPIGTRGPARLTLLVDGVEETLRPAKGFLSRRSYRVEVVSATRDCRYVLVPNS
                     SDTSRLRRDKRRLGVFTSTGDGKDSAVWENGERRSTAAPEPYDAAVGYALAAAYGTGAE
                     PMWHEALDAVTELWP"
     misc_feature    22705..22707
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(23337..23351)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            23480..23968
                     /locus_tag="DJ64_RS01400"
                     /old_locus_tag="DJ64_27140"
     CDS             23480..23968
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123099.1"
                     /locus_tag="DJ64_RS01400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27140"
                     /product="CbrC family protein"
                     /protein_id="WP_037643555.1"
                     /transl_table=11
                     /translation="MGDSLPHFRYHPDPVATGSIRASADRCVCCGRSRGWIYTATFYTA
                     CDVDGPFCPWCIADGSAAERFEGDFTDCYGLDDVSMDVVHEVTRRTPGFHGWQQPHWLT
                     HCGDAAALVGEVGHAELARHPEALAQLGDFAPHLGGDAAAVLFRCTVCGSHLAYADAS"
     gene            complement(23981..24361)
                     /locus_tag="DJ64_RS01405"
                     /old_locus_tag="DJ64_27145"
     CDS             complement(23981..24361)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521001.1"
                     /locus_tag="DJ64_RS01405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DJ64_27145"
                     /product="hypothetical protein"
                     /protein_id="WP_037637698.1"
                     /transl_table=11
                     /translation="MGLMLFPGDGDVTSPDVEWTYSGFASFRGWLARIEGFTLDDMDGF
                     GGERPWSSVHTTLAPLLDHPDDHGELTPAQCAAILPRLEEVHDDHVADDSDPDVRQHVE
                     DVGRLITVLRICVAKDAELCFG"
ORIGIN
        1 ccggtccccc ggaccgccgc gccctgccct cgcacacccc tgtccccgca cgtccccgac
       61 ctgagcgtct cccgctcgta cacctcagga gcccacccat gcccgcagca gaaccaggtc
      121 tgcccgaaga gagctggcgc tggacggaac cgacgtggcg cggccacgtg gacgccgtgc
      181 gcgccggacg gcgtctcgtc ccggaccgct ggcccggcgg cgcccgtgcg gccgtcgccc
      241 tgtccttcga ctccgaccac gagacgatcc ccctccgtga cggcgagacc agcccgggac
      301 ggctggccca gggcgagtac ggcgcccgcg tcggcgcgcc gcgcatcttg cggctgctgg
      361 cgcagcacgg cgtccccgcc accttcttca tgcccgcggt gtcggccctg ctccaccccg
      421 aagaagcgcg cgcttacacg gaggacgggc acgagctggc ggtgcacggc tggatccacg
      481 agcggaacac gctgctgggc cgcgaggacg agcgggagct gaccgcgcgg gccctggaca
      541 cgctcgacgc gctgaccggc cgccgccccg tcggcatccg gactccgtcc tgggacttct
      601 ccggctccac gctcgccacg atgctggacc tgggcttcgg gtacgactcc tcgctgatgg
      661 ccgacgacga tccgtacgag atcgtcgccg agggacggcc caccggtctg gtggagatcc
      721 ccgtcgactg gatcagggac gacgcgccgt acttcacgat ggaccgcttc ggcgccgtcc
      781 gcccccacag ccgcccccgt gacgtggggg agatctggcg cgacgagttc gacgccgcct
      841 accgcgaggg cggggtgttc cagctcaccc tgcatcccca tgtcatcggt caccgctcgc
      901 gtctggtcgt gctgcgggaa ctgctcgacc acatcaaggc acaccacgac gtgtggttcg
      961 ccacccacgc ccagctcgcc gacaccgtcc gcaccgtgct cgacggcacc gccggcgccc
     1021 gtcccgtccc ctcggagcgc acgccatgaa cctgaagtcc gacctgtccc ccgggtcccc
     1081 cgcggcgggc ggcgcgtccg aaccgcagaa gctgaacgcg aagcagcgca aggccatcgt
     1141 cgcgggcacc atcggaaaca ccgtcgagtg ggtggactgg gccctctact cgatcttcgc
     1201 gaagatcatc gcggacgagt tcttccccaa gggcaacggc gcggtcgccc tgctgtcgac
     1261 gctcgccgtg ttcgccgtcg ggttcgtgat gcgtccggtc ggcgccgccg tgctcggcgc
     1321 gtacgccgac cggcacgggc gcaagaaggg catgacgctg accgtggcgc tgatggcggg
     1381 cgccggtttc gccatcgcag tcacgcccgg atacgagcac ataggggtgc tgtcaccgct
     1441 gctgctgctc gtcgcccgtc tcgtgcaggg cttctccgcg ggcggggagt tcggttcgtc
     1501 gtccgccttc ctggtcgagt ccgcggcccg cggccgccgt gccttcgccg gatcgtggca
     1561 gcaggtgtcg gtcgccggcg gcgtgctgat cgcctccctg ctgggcaccc tgaccacgtc
     1621 cgcgctcagc gacgaggcgc tgcactcgtg gggctggcgc gtcgcgttcg tcttcggcgg
     1681 gctcctcggg ctggtcggcc tgtggctgcg ggtctccgtc gaggacaccg agtcgttcgc
     1741 gcgcagccag gacagcggcc ggacccgcac caaccccgtc aaggcgatgt tcgtcgagca
     1801 cccggcggcc acgctgcgcg tcgtcggcat cacgatcgcc ggcacgctca cgtactacat
     1861 ctgggtcaac tacctgccga cgtacgcgaa tctgacgacc ggcatcccgc tgaagaccgc
     1921 gctgctgtcg cagacgctgt gcctggtcgt gttcgtgatc gcgctgccgt tcgcggggct
     1981 gctgtccgac cggatcgggc gcaggccgac gatggcggcc ttcgccggcg ggttcgtcgt
     2041 gctggcctgg ccgctgctgc atctgctggg cgacagtttc tggtcgctgt tcccggtgca
     2101 gctcgtgggc atgctgctga tcctcggcta ctcgtccaac tgcgccgtca tcatggccga
     2161 gcagttcccc gccgaggtcc gcgccaccgg catcgccctg ccctacgcgc tcgccgtcgc
     2221 cgtcttcggc ggcaccgcgc cgtacgtcac gacgtggatg cacgagagcg gccacagcgg
     2281 cctgctgtgg atctacgtga gcgccgcctc gctgatctcc ctcgtcgtct acctcacgat
     2341 gcccgagacc aaggacaagg acttcacgtg acccacgttc tcgtcaccgg ggccgcgggc
     2401 ggcatcggca gcgcgatcgc cgaggcgttc gccgcgcggg ccgcgttcct caccctgtcc
     2461 gaccgggacg tcgacgccct gcgcgccacg gccgcccgca tcgaggggag caccgcgatc
     2521 cgggccgccg acctgaccga ccccgacgcg ccgtcggacc tcgtcgaaca gatctgggcg
     2581 gcgcacgggc cggtggacgt cctggtcaac gcggcgggtg tctacccctc cctcgacatg
     2641 gccgacgtcg acgcggagtc ctgggaccgg ctgttcgccg tcaacctgcg cgcccccgtc
     2701 ctgaccacgg ccgcgctggc ccgcctcgcc gcggctgcgg gccggcccgc gtccgtcgtc
     2761 aacatctcct ccgggtccgc gctgcgctcc cgcccgggcg gcggccccta cgccagttcc
     2821 aaggcggccc tggagatggc gacgcgggcc gccgcgctcg aactgggcgc gctgggcatt
     2881 cgcgtcaacg cggtcagccc cggtttcgtc ctggtcgaca gcgacgtcaa cccggtgtcc
     2941 gccgagtacg ccaggagcat cgacgtcaat ccgctgggcc gccccgggac gcccgaggac
     3001 gtcgcccgcg cggtgtgctg gctcgcggga ccggaggcct cctggatcac cggtgagacc
     3061 gtacgcgtcg acggcgggtc gagcacgggg gcgctgcacc tgccgcggat ctggcaggcg
     3121 gacggcaccc gggcgactcg caccacgcac gcagaggcac cggtgggtgc cggcaccacg
     3181 acggaggaag ccacccgatg agcgacatca cccaggacgc ggccgcctac accgtcgtcg
     3241 gcggcggggc gatcggcggg accctcgcct tcgccctggc ccgcgcgggt cacccggtca
     3301 ccgtcgtgga cgccgacccg gcacacgtgg aggccatccg cacgcacggt ctcgtgctgg
     3361 cgcggggcga ccgccgtacg agcgtcccgg tgcgcgccgt gacgcccgac gccttcgacg
     3421 gcaggctcgg ccgggtcctg ctggcggtga aggcgcaggc cacccggggc gcggtcgagt
     3481 ggatcgctcc tcgcctggag cccgacggct acgtggtctc cgtgcagaac ggcttcaacg
     3541 aggacctcat agcggagtac gtcggcatcg gccgtacggt cgcggcgttc gtcaacatct
     3601 tcgccgacgt cgtggagccg ggggtgatcc gggacggcgg cgcgggggcg ctggtgatcg
     3661 gcgagcccaa gggcgcgccg gtcggggaac gcgtccggtc gctggtcgcc gacctgcaga
     3721 gctggggtcc ggcccgggcg agcgacaacg tcgagggata tctgtgggcc aaggcgggct
     3781 tcggcgcgat gctcgcggcg accgctctcg cggacgctcc catggccgac ctgatcgacc
     3841 ggcaccggcc ggccatggcc gccctcacgg cggaggtctt cgcggtcgcc gaccggcgcg
     3901 gggtcacgct tcaggcgttc gacgccttcg acccggagcc gttccggcag ggtgcggatg
     3961 ccggagcgcg cgaggccgcc ttcgaccggc tgaccgcgtg gctgcgcacg cagagcaagg
     4021 accgcagcgg catctggcgt gacctggcgg tacggcaccg ccccgtggag gtcacgacgc
     4081 actaccgcga cgtcatcgcg tacgccacgg aactgggcct gccctcgacg ctgctgggca
     4141 cggtgatgga cgggctgcgt gagctggagg gcgcgccgga gacgatgtcc gaggggcgtc
     4201 tcgacgcgtt ggaccggctg accgggccga acctcgacga ctgggacccg ggcgttcggg
     4261 tgcggcgctg gctggaggag caccgcgagg agatggtcgc cgatctggcc gcgtacaccg
     4321 cgcggggcag tgcgagcgac gacctcgacg cgctggacgc gtgcctcgcc tggctgcgcg
     4381 gctggctcga cgagcggctg ggcgcggcgg agagcgagga gatcctcggg cgtgaggacg
     4441 ccggggacgt cctggtccgc cgctacccgg cgcgggacgc cacgacggcg gacgcgcggc
     4501 cggtgctgct gctcgggcac tacgacaccg tgtggcccac cggcacgctg gagtcgtggc
     4561 cgttccgccg cgacggcgac accgtcaccg ggcccggtgt cttcgacatg aaggcgggcc
     4621 tggtccaggc ggtgtgggcc ctgcgcgccc tcgacgccct cgggctgccc cgcccggccg
     4681 tcaccctcat gctcaacggc gacgaggaga cggggagcct cgcctctcgc gacgcgatcg
     4741 tggagacggg gcgggactgc cggctggcca tggtgttcga agcggcggtg gacggggcga
     4801 tcaagacggc ccgcaagggc gtgggcctgt tcacgctgac ggtcaccggc agcgaggcgc
     4861 acgcgggtct ggacccgacg gccggcgcga gcgcggtcga cgaactcgct taccagatac
     4921 tccggttggc ggaactgcgg gacctggagg cgggcacctc cctcaacgtc ggcgtgatcg
     4981 agggcggcac ccgcggcaac gtcacggcgg ggcgcgcctc ggcgcacctg gacgtccggg
     5041 tggccagtgc cgcggagcag gaccgcatca cgcgggcgct cgcggacctg cgccccgtgg
     5101 acccggggac gcggctggag gtcacgggcg actggaaccg tcccgtcttc gaacgcggcg
     5161 aacaggtggc atgggcggcc gggctggcga aggacgcggc gcgccggctc ggacatgacc
     5221 tcgcggaggc ggcggtcggc ggggcgagcg acggcaactt cctcgccgcc gcgggtgtgc
     5281 cggtgctgga cggcgtcggg gcggtcgggc acggagcgca cgcgcggacg gagtgcacgt
     5341 cggtcgcggg catggtgttc cggtcggcgc tgacgggcgg ggtgctggtg cggctcgccg
     5401 gggagtgagc cgggcgtagc cgctgcggca cgccgcctgg accatgaccc tggggccacc
     5461 cccaggcctg gcgtccaccg actggtggac gccaggttca accggatgcc tctgtccggc
     5521 aactgccctg gccagccagg cttttcggca tgaagacaat ctctgtgcgc atggcgcgct
     5581 ggagcgcaca tcacccttgg cgggccatcg ccggctggct ggtgttcgtg gtgctctgcc
     5641 tggctgtagg cgccgcactc gggaccaaca gtgcgaagac ggcggactac cgggtcggtg
     5701 aggccggacg cgccgaggcg cttcgccggg agcggcacct ctgcgggaga cggcacctgt
     5761 gcgggaccgc gtcggcctca gctctcgccg tgtccggtga gccaggccag ggcctgcgcg
     5821 cgctcagcct cggacggggg cggtttcagc cggtccgagt agcggatcag ggcgtggtcg
     5881 cgggccgccc gcaggccgat cgcgcgacct tccgaggaga gccgggtgtc ctcggcgacc
     5941 tcccgggcgc gctgccacca gctccggctg ctggacttca cggcgtagtg ccagagcggc
     6001 tgcgcggggt cggccacgcc cagcagcacc cggtggagca cgcggtcgcg gatacccggc
     6061 gcgccgatca ggcggtcggc cacgaggagc ggatgctcgc cgtcgaggcg cgcccggacc
     6121 aggacgtacg tcatcagctg gcccacgtcg tgggcgggcg aggtgacgaa gtcccacagc
     6181 tccgcggcct tggtctcgtc gggggcgccg aggtgcgtga gcagccggag cttgtccttc
     6241 cagacaggcc gggcccggtt ccaccaggag accagccgtc ccgcctccgg gtggtccagg
     6301 tcgagggcga ggcaggtcag tgtcaccagc gggtggcgcc actccgtgta cgtggtctcg
     6361 tacttcttgg tgaggtcctt caggcggtgg ggcaggagcg cctcgatctc gtgcctgccg
     6421 gcgaggccgt gggagtggag gagttcgagg cagaagccga gtccttggag gccggtcccc
     6481 gggtccgcga cccgttcgcg gagccagtgt gcgtccgcgt cggtgagggt gcggtagtgg
     6541 tgccacacgg cgcacagcgc gccctcgtag gtgtcgaggt cggggccggt ggcggacgac
     6601 agggcgtcgc gggcggcctc gtagcggtcg agggcggcca gcgcttcgga ctgttcggtg
     6661 ccggtgagca cggcggagcc tggccgaagt gcttcctcgc ggacgagttc cgcccggtcg
     6721 cgggcggcgg ccgcggcgag gacgcgcagg gcgtgcggga ggcgttcgtc ggtggagaac
     6781 cggaccgccg cgaggccggc atgcaggtcg acggagccgg gaccggcgcc cgtgtcacgg
     6841 cgccggtcgg tcacggcagc gccgatcagc gcttcgtaca gcccgcgtag tgagctctcc
     6901 gaagcgccgt gcgcggtcag ttcggcggcg agggcggacg ctgctcgtac ggcgtcgggc
     6961 tcgtggagtg tgcggtgcag cgacagccac gcgcggagcg caccgcggtc gcctgcgagc
     7021 gcggcctcac ggacgacgcg cagcccttgt gcggtgggca cgtcggacag gacgccgtac
     7081 gcccggaggc cgtacacggc gacgatgtcc cacgcggcgg cgtggccgtg gcgcagcagg
     7141 gcgtggagca cggcggaccc ggcgttccac tccgtcagcc gtccggcgta ctcggcctgc
     7201 caggcgtgca gcagtcgctc ggtctcgtcg gcggtgagtt cgtcccgctg ctccagcggg
     7261 atcgcgaagc gcgccgcggc ggagacgtcg ggggcctcgt cgaggcgggc gtggagccag
     7321 gcggcctccg ccggggacag cgggccgtac gtgaggcggg gcgcagcgcg gtccacgggt
     7381 tcgccgagca tgctgaggaa ctggcggacg ccgtcggggt ccgacgggtc cggcagcccg
     7441 tcgtcgtccc ggtgggtgat ccggtccagc cggaacgcgg acctgggtcc gccgtcgacg
     7501 atgccgaagc ccggcggtcc ttcaccgagc ccggcggcga cggtggcgtg gtcgccgccc
     7561 cagtgaagca gcagttcgcc tgtcagcgtg ccggagcggt cgaaggcgtt cctgtgggcg
     7621 tcccagtgcc agtaggcgaa ggaggcgggg cgggtggtgt cggtggcggt gccgcccctg
     7681 ccgcccctgg ccgcgaggag gagggcggcc tcctcgtgac cgtcggcctg ggtgaagcgg
     7741 cgtcgggtcg gcggcggcag gacgaagaag ccgttgcagg caaggccgtt ccaccacgtg
     7801 gtgacggcgg cgaggtccga cgacggacgc gggctgttca cgagctcccc cagcggttcc
     7861 ccctggccgg acgacgctcg gctcagggtc ggcgttcggc ctcaccttgc catacggcgt
     7921 cgccccgtag ggtgtcggag cacggtgtgg aacggacggg gaggtacgcg tggcgcgggg
     7981 gaccgtgagg ggacaccggg tcgtcggtgc cgggctggtg ctgttgctcg cgtcggccgg
     8041 ctgcggctcg ccggccggcg acagcggtga cggcggggcg accgccgctc cgccggtcag
     8101 ggacaagggg ccggtgtgtg tcggtgaggc gccggccgac ggggtgcggg tgctgcgagg
     8161 cggtggcttc cggctgccgg gcgggacggg tgtgcagtac gcgggggcgt cggcggacgg
     8221 cagcagccgc acggcgacgc tgcgcgaggg cgcccggtac gaggaggggc agcgcgagtg
     8281 gaaggtcgcg gtgggggcgc gggttccgct cgccggtcac gcgtacacgg tgcggcaggt
     8341 gtgctcctac cgtgtcgtgc tggaagcggc ctcggcgcgg gacgcgtcgg cgttggccga
     8401 ggctcccgcg tcgatgacgt cgacgggtgg ggaggccgac gcgggtctgt gcttcaccac
     8461 caaccgtgcc gtgctcaagg cggcggccga cggattcccc gccgagggtg agagcctgtc
     8521 cctggtcggc aacggcgggg tccggcgctt ccccacgggg ctgtcgctca ccgtgtccta
     8581 cctggacgcg gaggcgggga cggcgggcat cgcggcgaac tgcgcggccg tgccggtcgc
     8641 ggcgtacgag gagttgcgtg tcggtgatcc gctcgaactg gggggtgttc tcttcgaggt
     8701 caccgacgtc acggaggcgg tggtgcggct gacccgtccg gccgcgccac gcccctgaac
     8761 gccgtggtca cgctgtcggg tcggcttgct ccccggcctt cagcagtctg cggcgccgca
     8821 cgacgaggaa gacggcgccg ctgagcagca acggggtgag gacggcggtg acgagcatgg
     8881 ggagcgtggc ggtgggcggg tcctcgaccc agcgggtcgt cagcacccgc gtcggttccc
     8941 gagggtcgta ggtcaccggg accgcggctc cggcccggag gccctcgggg cgtttgcctc
     9001 cccagtcgtg cagctcggtc tcgaccgtgc cgtcgggacc gtcgaagcgc accttgacgt
     9061 tgcccgcgtc gccgtacttg ttcttcgacg cggcggtgac ctcggccacc acggatatgc
     9121 ctcgggaccg taggtcgttc accagcgacc ggccggggag gaggaacatg aggaaggccg
     9181 tgagggtgac cagggccaga ccgaacaggg cggcgatcaa gcgcttctgg ggcaggggcg
     9241 gtcggttcgg cgcagccctg gacctacgcc actcctcctc ggcggcccgc ctctccgccg
     9301 acaggggcgg acgcgtccag ttctcgcgac gcggccgtcg cttcttcttc ttgcccacgg
     9361 ggagcggctc cttcttctgc acgagcgggc ccctgtacac aaggacggca acccgccaac
     9421 tgtcggggac gagttcggat catgacggac gactggcgga aagaccgtat cggtgctgcg
     9481 ccgcgcgggg acaacccgac cgtgacgcga aggcccgacg ccggcttcgc ggcgatcggt
     9541 gatgtccggt cgagggcggc catcggcgac ggacccggct tgctgcgggc gccggagtga
     9601 gtaggaaggc cgccctcctc ttaccgtgat caatggcttg atttcaccta ccacctatct
     9661 gcggcagccg cgaaggatac gcatgccgag ccaccacagc ggcccggcgc gttcgagtcc
     9721 gtgcaccccc aacacccgag ggagaagcat gcgtaccgag atcgttctgt cccaggatgc
     9781 ccccgagctg gacctcgacc tggacctccg tgtgtccgac ctgccggagc aggccgagtc
     9841 gttcgggcag ggcacctaca cctcgccgag cagctacgcg atcggcacgc gctgccctgt
     9901 ctgctgctga cgggttgaag cccctcaggg gctcttccga gcggggcggt gccggaaccg
     9961 ccccgctctt ccgtacgacg gcgacgagga gagcacacac gtggcggcgg agtgcgaagc
    10021 cgggcaggcg tctgcagcat tcgaagtgag ggatcccgta ctcgtccgca tggcgagccg
    10081 gccacgcggc accgacctgg aaggcgtcga cgccgccgat ccggtgcccg gggcacggcg
    10141 gctcgccgcc gacccggtgc tcggccaggc ggtgcgggtg gccagcggct ccctggcgca
    10201 gggcctggac cgtctgaccg gtgacgaggg tgtggccgcg ctggggcgca agcggacgct
    10261 gagcgccgcg cgcaccctga cacggtacgc ccgccgggcc gcggcccgtc cgacgccgtt
    10321 cggtctgttc gccggcgtcg gcagggcccg cttcggttcc gcggccaagg cggaaccggg
    10381 ggccggtgag gtcgcggtcc ggctggacgg ggcctggctg cggcgtcgcg tgatggcctg
    10441 gctcgccgag ccgtccgtac gccggcgcgt ggacgtcgtg ctcaacgacc tgtgcttcgt
    10501 gcgcgacggg cggctgtgtc tgcgcaccgg cggacaagag cggtcggtgc gggacaacgc
    10561 gctggtgggc gcggtgcggg atcggacgcg gaccctggtg gggtacggcg acctgctcga
    10621 taccctcacc cggcgattcc cctcgctgga tgccgagcgg ctcgacgggc agctcgccga
    10681 gctcgtccgg cgcggcttcc tcctcacctc cctcaccccg caccggatcg acaccgcgct
    10741 gctcgacggc atcgaggcgg tgctcgacga ggcgcttccc gacgacgcgc gggcgttgcg
    10801 ggacatccgg gcggcctgtg cgcggcatga gcgggactcc ccgggggcgg gcggcgaatc
    10861 ctggcaccgg ctgctggacg aggtgcggcg tctcgacgtg cccgacacgg acggtgacgc
    10921 gcaggcccgg cctcccgtgc acgtggacct gcacaggcgc ggcgagttcg tcctcccgga
    10981 gaccgtcggg cgtgaggtgt gccggtacgc gggcgcgatc tggtcgatca ctccggagtg
    11041 gacgacgctg gcgcacatgc gggactaccg cgaccgcttc atcgaacgct acggcaccgc
    11101 ctgcgccgtg cccctgggcg agctggccga cccgcaccgc gggctcggtc tgcctcccga
    11161 gtacggcgcg gagcccacgt acgcgcgcac cgggccgggt gacgaggtgg acggtccgcg
    11221 gcgggcgttc gtcggtgagc tgatccagga ggccgtcctg tccggcggcg acctggtgct
    11281 gacggacgag gtcgtacggc gtctcgcgga cgtcgcccgg cacgatccgg aggccgcgcc
    11341 gccacgcggc ctcgaactct gcttccaggt gctcgccgac agcaccgccg ccctggaccg
    11401 cggcgacttc cgcctgctcg gcagcccgca catcggggcc tgggcggcag gcgcgaccgc
    11461 ggggcgcttc gcggaggccg ccggtctcac cgcggacctg acccggctgg ccaccgagac
    11521 ctcgggcgat cccgacggcg acgtgatcgc ggcgcaggtg gaactgctcc cccgtgaacc
    11581 gcgcgggctc aacatcgtcc aggtgccccg gctgctgccg taccgcatcc ccgtcggtgt
    11641 gcccgacgac cgggacgacc cccgctgtct ggactggcgc accctgctcg tcgccgccgg
    11701 ttcggacggg ctgcggctgc tgcacccgga gagcgggcgc cctgtccggc cggtgctccc
    11761 gcacatgctg gccctggacg cgcaggcccc gccggtggcg cggttcctga tggatctggc
    11821 gacggcacgg ccgcgggtgt ggtcgggctg ggactgggcc gggcacgaca ccctgccgta
    11881 tctgccgcgc gtgcggtacg gccgggtggt cgtgatgccg aagcggtggc tgcccgggcg
    11941 ccggctgcgc gatgcggcgc gcgccaaggg cgccgaggta tgggaggagg gcctcgacgc
    12001 gtggcggcgg cgtctcaccg taccggaccg gctgcacatc gcgcgcaacg accagatgta
    12061 ccccgtcgac ctgcgcgacc ggtgggacag ggagctgctg cgctccgaac tgaccgccct
    12121 gcacccccag ttcgtcctct acgaagatct gaccaccgac ggcgcggggc tcggctggaa
    12181 cggcgggcac agcacggaga tcgtggtgcc cctcgccggg gcgcggccgt ccggcggggc
    12241 cacggggacg gggagccggg ggcaggcgcg aaccgcgccg ccggtccggc tggctcccac
    12301 ccggttccat ctgccgggcg aggactggct gttcgccaag tggtacgcgg agccgtcggc
    12361 ccacgaagcg ctgctcgcgg atcaccttcc cgccgtgctc ggcgagatcg aggacgacgt
    12421 cgaccgctgg ttcttcgtgc ggtaccagga tcccgacccg catctgcggc tgcgcttcca
    12481 cggcgacgtg gaggcgttga acggccgggt gctgcccgcg ctcagccgtg cgtcccgcgt
    12541 actcgtcgag agtggtgcgc tgcgttcgat gactctggac acctaccggc ccgagagcga
    12601 ccggtacggg ggcgaggccc tccaggaggc ggccgagcgt ctcttccgga cggacagcct
    12661 gtcggcggtc gtgcacctgc gtgcggcgcg cggcgcggcg cggggcctgc ccgccgacgt
    12721 cctcgccggg ctcggacacg cggtgcttct cgagtccctc ggggactggg actggtgcgg
    12781 ctgggtcgac cggatgttca ccaagtccga ggagcacgag gtctaccaac ggcagcgtgc
    12841 cctcgccgac cggctgatca cgccggggaa cgtggtcgcg tctgccgtgg aagcgctcgg
    12901 agcgcccgcg ctccgctcgc tgtgggccga ctccgacgag ccgcgtgcgt acgggcgggc
    12961 ggtcctctcc gccccggagg ccgaccggga cgaggcgctg ctgtctctgc tgcacatgcg
    13021 gcacaaccgt cacttcggca tcgaccggtc ggcggaggct cgcggatacg cggtgctgcg
    13081 gggtgcggtg cggagtcatc tcgggcgaca gcggcatcgc ggtgaccacg gcaacgggaa
    13141 cgggagcggt cgatgagcgg ggcggcggac gtgagcgcca agggcggaga ggctcgcgag
    13201 cgtgcggacg gtgccgccac ccggggactg cgtgagcggg ccggtgccgt gtccgccgcg
    13261 atcctggaac ggctggccga tcccgccgcc accgtggcgg ccacccgcat cccggccgag
    13321 gccgccgacg acggggtcgc cgagccggtc tgggcggagc tgaccctcgg cagcggaagt
    13381 ccgggactgg cgctcgcctt cgccggggcc gcccgggacc cggagcggca ggtcccgcgc
    13441 gcccatgcgt acctcacggc gggcacgcgc gccgtctccg gtgggccagg cgccgcgagc
    13501 gggatcttca aggggcccgg cgccctcgcg ttcgccgtgc tggtcgctca ccgcaccacc
    13561 ggcgggtacg tgtccgcgct cggccgcttc gacgcctacc agcgcgatct cgtacggacc
    13621 gtcctgccgc cggtcgagga ccggcccctg tcgaccatcg ggcactacga ggtggtgcgt
    13681 ggactgaccg gtgtgggccg ctatctgctg gcgcgtgcgg agacctgcga ggagccgctg
    13741 accgcggtgc tcgaccacct cgtgcgtctg tcggtgggca ccgtggagca tcagggggca
    13801 cgggtgccgc gctggtgggc gctggacgcg ccgcggaccg gctcggagga ggcgttcccc
    13861 ggtggtcatc tcaacctcgg cctgtcgcac ggcgtcgcgg gaccgctcgc gttgatggcc
    13921 ctggcatggg agcagggcgt gcgggtgccg gggcagcagg aggcgatgga ggccacggcc
    13981 ggcctgctgc gcgcctgggc ggtgacggac cggcacggtg tcttctggcc cggccacctc
    14041 tccttcgccg agtggcggcg cggtcccgcc gcgtacgacg gcagggccaa gtggccggcc
    14101 tggtgctacg gggctcccgg ggtgtcccgc gcgctgcaac tggcggggcg ggccctcggc
    14161 cggagcgacc tctcggacct ggcccgcgcc tcggtggacc ggctcctcgc cctcccccgg
    14221 tcggactggg ggatcaacga ccatgcgctg tgccacggtt gggccggagc cctgcaccag
    14281 ctcggccggc tcgacgagga gtggcgggac ccgcggctgg cccggctgcg ggacgacatc
    14341 gcctccgaac tcgtcaccgc cttcgacccg gcgctgccgt tcggactgcg gttcaccatg
    14401 accaaggtgc cgttcggctc cgacgtgtcc ggttatctgg acggcgcggc gggggtcgcg
    14461 ctcgcgctcg actcgtacgc ggtggacggc acgccggccg actgggacat gccgttgctg
    14521 ctggcctgac cacgagttgt ccacgtgtcc atgtggctgg caccagttcc cggcggggcg
    14581 ttcgccggat gggcggtggc ccccggtcct cctagcctcg gagcatgatc actcgtcgac
    14641 gcctcctgat gtcaactgcg gccgctgcgg tggccggcac ggctgtaccg gcggcagcgg
    14701 ccacggctcg gtcaccctca cggtcactgc agcgggacgc cgacgcgctg cgggacgccg
    14761 gggtgaccgg ggtggccgtc cgcctggaca ccccgcacgg gacggtcacg gcccggtcag
    14821 gcgtcagtga cctacggtcc cgcggcccgg tgccggaggg tgggtacctg cgtctgggca
    14881 gcacgacgaa gacgttcgtc gccaccgtgc tgctgcgact ggtgggcgag cgccgggtca
    14941 ctctggacca gacggtggac gatctgttgc cgggggtcgt ccagggcgcg gggaacgacg
    15001 gccggaccat caccgtccgc catctgctgc ggcacaccag tggtctcccc gactacgtcc
    15061 ccgacgtctt ccccgagcag agcgccgaga cctacttcgc ccgccgatgg cgcgcgtacg
    15121 aggccgagga gctggtgcgc ctcgccgtgc gtcaccggcc cgccttcccc gccgggacgg
    15181 ggtgggcgta ctccaacacc aactacgtgc tggccgggct gatcatcgag cggatcaccg
    15241 gacgcgggtg ggagcgggag gtggccgacc gcattctccg cccgctcgga ctacggcaca
    15301 ccgacaaccc cggcacccgg cccttccttc cgcacccgca cacgtccaac taccagcagt
    15361 tcaccgaggg cggcccgctg gtcgacacca cactccccta ccgtcccttc gacagcgggg
    15421 cggacgggtc gatgaccggc acggcgcggg acctcaaccg cttcttctcc gcgctggcgg
    15481 gcgggcggct gctcgcgccc gccgaactca acgcgatgcg ggacaccgtg gaggtgccgc
    15541 cgggcaacgg gcaccccgtc ggggcacggg cggggctggg gctgttccac acgcccttgt
    15601 ccggtggggg tggctgtctg ggacacagcg gaagcggatt cgggtacgtc gtcgagacgg
    15661 cgacgaccct ggacggccgg cgcaccgtca ctgtgtccgc gcacagccgt tcggccgatc
    15721 cggagcaggc agcacgccag gagaccgcac tgcgtgacct catcgaccac gctctcagtc
    15781 gcggcgactg agacaccggc agcaggacag gcgggcggaa aaggtgatgc gccgaggccg
    15841 ccaggtcgtc agaatcacgc gcatgaccgc cgagatcaca cgcatcaatc cgccgcacct
    15901 ccatgcgact ccgggatacc accacatcac cgtcgtggag gcgggccgga cggcttacct
    15961 ggcggggcag tgcccgctcg acgcgtcggg gaagctcgtg ggcgagggtg acctggacgc
    16021 ccagatcgac caggtggccg ccaacgccct cgcggccctg aacgcggtgg gcgccgggcc
    16081 ggaacacgtc gtccgctccg tgatctacgt cgtcagcgac gacgtgccgg tcctgggctc
    16141 cgcctggcga cgcctgacct cgtcggtcgt gggaccggcg ttcaccaccg cgagcacgct
    16201 gctcggcgtc gcccggctcg gcttctcggg gcagctcgtc gaggtcgacc tgacggcggc
    16261 cctgccccac tgaccgggac gcccggacgt cccgtggctg aacagcccgg agtgaggtgc
    16321 gtcggcgccc tggccggtca ggggcgccac tcgtagcgga cgtccggctc gcgctcctcg
    16381 ttgcgctgac cgtcggtccg ctcccgggcc acgaagccgt gccgctcgta gaagcgccgc
    16441 gccgcctcgt tgacctggaa cgtccagagc gtcagccctg acggactgcg ttccttcgcc
    16501 acgtccacga ggcgtccgcc gatccccctg ccctgccatg ccgggtcgac gtagagctgg
    16561 tccaggtcgt ttccttcccg caccatcatc gcgacgaccg agccgtccgc caccgccacc
    16621 cacgtctcct ggccgggcac gaccacctcg cgaatccacg tccgcacctc gtcgtccgta
    16681 tgcgcccggc gcacgcccgg aagcgccgcc gtgaaggacc gcagccacac ctcggccacc
    16741 tccgccgcgt cggagccggc cgcacggcga atgacgatgt cgttgatctt cacggcccgc
    16801 atgctcgcag atctccgctg ccggccgcac cggatttccc tcccacgccc tcggcgctcc
    16861 cgtcacttgt cgccgtgcac cacggacccg cccggcgccg cccccttgcg ggatcaggct
    16921 actgacagcc ggggcagatc atggccgcgg tcgcgctggt ccgccgggtc gcggaggagg
    16981 gcagggaggt gaccggggac gacctggacg gcatccggaa catctgccgc tgcggtacgt
    17041 atccgcggat ccgcgaggcg atcaggtccg cggccgggag gatgtgagcg gcagaggccg
    17101 ggcggtcccc gggccgtcgg tcaggaggtc cggggagtca gcacgtcttg gaggagggcg
    17161 ccgtaccgcg agaccagctc cgcgcggtcc atgcggagca ggccctggtc cccggccacc
    17221 cacagggcgt agaggagtcc tcccgccacg gctgccgccg tgcgcgcgcg gacgtcggcg
    17281 tcggggccgt cgaggcggcg gcgcaggggc tcgacgaaga gatgttcgtg tgtgtccctc
    17341 agccggtcgt ggatgtgcgg ctcgttgctg ccgtgaacca gcgcgaggaa gacgccgcgt
    17401 gcggagccgc cgaggtcgag gagaagttcg gcgaggcctt cgcccaggtg ctccaggggt
    17461 acgtcgagca gcggctcgtc gtcgagcgtc aggtgcatcg tctccaggaa cagcagttcc
    17521 ttgctcttga agtgacggat caccagagcg gggtccgtgc cggcctcggc ggcgatctga
    17581 cggacggtgg tccgtgagta gcccctgctc cggaagagcc gggtggcggc cttgtggatg
    17641 gactcgcggg tcgacacgct ggagccggtc tgcagcatgc gggccaggat aggcgtccgc
    17701 gcgcttcgca actgcgcgtt cacgcgttca cggcagccgg acgcagattg cgtgcgtgtt
    17761 tcaagaagtt cggtcaacaa tgttgactcc cgctcggggc ggctgcacat tacttgacgg
    17821 tagaaccaat cggtaaccgc tcgaccaggc actcttcccc gcctccgacc gccccgcccg
    17881 ttcgtcggca tgccctgccg tccgccgcac ccgcagcccc gtccccctcc ggaaagggat
    17941 cacatgcaga agcatgtctc gcgccgcaat gtcatggcca cctcattcgc actcgccggc
    18001 gcgctcaccc tgagcctcac ggccggcggc acggcccagg cgtccgaccc gctgcggtac
    18061 gtcgccctcg gcgacagcta cagcgccggt tccggtgtcc tgcccgtgga cacgagtaac
    18121 ctgctctgcc tgcggtccac cgcgaactac ccgcacgtca tcgcggaccg gacgggcgcc
    18181 cgcctcaagg acgtgacctg cggtgcggcc cagacgaagg acttcacctc gtcgcagtac
    18241 ctgggcgtcc cgccccaggt gaacgcgctc agcgccgaca cggatctggt cacgctgacg
    18301 atcggcggca acgacaacgg caccttcatc aacgccatca cgtcctgcgg cagcgcgggg
    18361 ctgctgaccg ccggcaaggg cagcccgtgc aaggacaagt acggctcgaa gttcgcggac
    18421 gagatcagga acaacaccta cccggcgctg aagaacgccc tgaacgcggt gcgcgccaag
    18481 gcgcccaacg cccgtgtcgc tgtgctcggt tacccctgga tcacccccga gaaggccgac
    18541 ccctcctgct acctgaagct gccgatcgcc tccggtgacg tgccgtacct gcgggacgtg
    18601 cagacccacc tgaacgcggc ggtcgaacgc gccagcgagg agacgggcgc caccttcgtc
    18661 gacttcgccg aggtctccga cggccatgac gcctgcacac cgctcggcac ccgctggatc
    18721 gaaccgctgc tcttcggcac gagcctggtg cccgtccacc cgaacgccct cggggagcgg
    18781 cggatggccg agcacacgat ggaggtactc ggcctgaagt agggcgccct cacgacaccc
    18841 tcggcgagcg gtccggtcac cgatcgtcgc cgggagccag gtgatgaaca acgcctctgg
    18901 cggcggccgg agttcgcttc ggaccgccgc cgcaggtcaa ggagcgctac gcgacagccg
    18961 tcccttcgag ttcaaccatc tgaccgggta tggccaggcg ggtcacgccc agcatggtgg
    19021 tggtcggcgc cacgccggcg gcgccgagac ggcccgccag aacgccgtag tgccggaaca
    19081 gcaggtcgac gtcggtcgtg tagacgttca gccggacgag gttcgccagc gacatgccgg
    19141 cctcggcgag caccgcctcg acgttgtcga cgctcagcgc caactgggcc gccatgtcac
    19201 cgtcgtgctc gggcttgccg tcctcgccca tcgcggtctg gccggagatg aagagggtgc
    19261 gggaatgccc ggagacgacc tctccctggt tgaagcccct ctcgaccgac cacgacacgg
    19321 ggttgaccgc gttacgttcc atcaccgcat ctgctccatc cgtcaacgtg tgggttggca
    19381 ctgcctcgac gtcgtgcggt gaaccctcgc aggaaaacgt gacatctccg gtcacgtatt
    19441 tcgttagggt ctttcccatg cgagccgacc gtctggtgtc cctcgtgctc ctgctgcgtc
    19501 aacggggccg gatgaccgcg gaggcactcg cccgcgagct ggaggtgtcc acccggaccg
    19561 tgctgcggga catggaggcc ctgtcctcgg cgggcgtccc ggtgtacgcg gagcgcggcc
    19621 ggcacggcgg gttcgcgctg ctgccggact tccgcacggc gctcaccgga ctgacccacg
    19681 acgaggcgct cgccctcctc gtcgccggat cgcggcgcgg ggcgcagctg ttcggcctcg
    19741 ggtcggcgct cgcctctgcc gtgctgaagg tggtcgacgc gcttcccgac ggcttgcggg
    19801 agaccgccgc gggcgcggcg cagcggctgc tggtcgaccc ggagacggac ctgctggccc
    19861 ggccggtggc tccggaggag gtgcccgacg cggtggcgac gcaggtgcgg cgggcggtct
    19921 tcggcaggca ccggctgcgc atccactacg cggcggtgaa ccagctcccg aggtggcgca
    19981 ccgtggaccc gatcggcatc gtcaccgtca aggaccaggg ctacctgctc gcccgccggg
    20041 ggtcggagga ccgtacgtac cggctgtccc gcgtgctggc ggccgagcag ctcgacgaac
    20101 cggcccggcg cgcggactcc gtcgacctgg gccgcgcctg gcgggagcgg gaggtgcggt
    20161 tccgtacggg cggtgacacc acggaggtgc tggttcgggc ggatccggca cgccgggagc
    20221 ggctggccgc cacggctctg gcggtgaccg gcgaggggac ggacgcggaa ggccggcttc
    20281 ggatgacggt cgtcttccag gacgctcggc atgctgaatg ggctctgtgg gagcacgctc
    20341 cgggggcgga ggtgctggct ccggagtggt tgcggacgcg gctgggtgag cgggcgcggg
    20401 aggtggcacg gctctacggc gacgcgtcgc cggagccctg aaacccgctg tccttccccc
    20461 gccggccgtg ccaagatccc ccgcatgaca gtgcgctacc cctctcccct gcgtcccggt
    20521 gaccgtgtcg gtgtgacctc tccgtcgagc ggagtaccgg aggcactgcg cgcacgactc
    20581 gaggtggccc tcggtgacgt ccgcgcccgg gggtacgagg tcgtcgtcgg acggtgcatg
    20641 gacggttcgg ggcacgtcag cgcctcggcc gccgagcgtg cggacgagct catgtcgatg
    20701 ctgaccgacc ccaccgtcaa ggcgatcgtg ccgccgtggg gcggggagac ggcgatcgac
    20761 ctgatgccgc tgctggactg ggaccggctg cgggacgtgg aacccacgtg ggtcgtcggg
    20821 tactccgaca tgtcgaccct gatcacgccg ctcacgctgc tcaccggcac ggcgaccctg
    20881 cacgggaaca acctgatgga cacgccgtac cgcgtgacgg agggcctggt gtcgtggttc
    20941 gacgtcgtgg ccgcgccgcc gggccggtcc ttcacgcaga caccgcccgg acgccaccgc
    21001 accgtcggtt tcgacgactt cgccgtgttc cccgacgtac gggagtacac gctcgacgcg
    21061 gagggcggct ggacgcggct ggacggcgaa ggggacgtgg aggcggaggg caggctgatc
    21121 ggcggttgtg tcgagacgct gtgcaacctc gcgggcacgc cctacctcga cgtgtcggcg
    21181 ttccaccgcg acagggcgcc cgaagggctg ctcgtgtacg tcgaggtgtg cgacagcgac
    21241 gcgttcaccg tctgccgtca tctgcacggg atgaagctcg ccgggttctt cgagggtgcg
    21301 aacgcggtgc tggtcggccg gacgggcgcg ccggacagtc cctccctcac ccagcacgag
    21361 gccgtcctcg acgcgctcgg gtccctcggc gtgccgatcg tcgccgacgt ggagtgcggg
    21421 cacgtcccgc cgtacatgcc gatcgtcaac ggcgcgtacg ggcgtgtggt gcacacgacg
    21481 ggacgcagcg cgttgacgca gacgttgcgg tgagggggcg ggaggcgaac aaggagcgcg
    21541 gtggcctgtc gcgtggtgcg cgccttgccg cgcacggtgc cgtatccgcc tcactggccc
    21601 ggcacagtga ccgggagcta cgtgaactgc tgaacgcggg acgtccgttg gggtcgggca
    21661 tcggcggtga gcgggtgctg ctggacgtcg acggtacgcc ggtcttcgtc aagcgggtac
    21721 ggctgaccga tccggagcgg cggccggaga atctgtactc cacgcggaac ctcttcgagc
    21781 tgccgctctt ctgtcactac ggggtcggcc cgatcggcgg cccgggcttc ggtgcctgga
    21841 gggagctggc cgtacaccgc atgacgacgg actgggtggt ggcggggcgg tacgagggct
    21901 tcccgctgct gcaccactgg cgggtgctgc cggacggtgg ccggccactt cctgaggaac
    21961 tggccgacgt ggaacgggcc gtggcctact ggggaggcgg ggcggaggtg cggcaccgca
    22021 tcgaggcgct gcagcggtcc tcggcgagtg tgctcctgtt cctggagtac ctcccatgga
    22081 acctgcacga ctggctcggt gagcggatgg ccgccggcga ggaggccgcc gagcgggcct
    22141 gcgccatggt ggacgacgag ctgagagcgg gcatcgcgtt catgaacgcc aacggggtgc
    22201 tgcacttcga cgcgcacttc gagaacatcc tcaccgacgg ccggcggctg ttcttctccg
    22261 acttcgggct ggcgttctcg tcccgtttcg acctggcgcg agcggaggcg gagttcttcg
    22321 aagaacaccg cgtgtacgac cggtgttacg ccgtcacgca tctcgtgaac tggctgaccg
    22381 tggctctgct cggacacgag ccggaggagc gcgcggcgtt cgtgcgggcg tgcgcggaag
    22441 gggcccggcc gacacggatg cccgcttcga tcgccgatgt cgtcgcccgg tacgcgccgg
    22501 tcgcggtggt gatgggggac ttccgccacc agttccggac ggtgagccgg accgcgcctt
    22561 tcccgttcac ggcgatccgg cagagactgg agaagtgcga tcagtgagga gccagggagt
    22621 tccatggatc cggtcgtgcc cacgcccgtc gcggatcagc tgttcgggca ggtgcagatc
    22681 gaactcgatc acgagggcgg cacgttacgc gtgagcgggg agggactgcc gacggtcgag
    22741 atccggcgca gcccggacac ggaggtggcg acgcatgtgc cgatcggcac gcgcggcccc
    22801 gcacggctca ccttgctcgt cgacggtgtc gaggagacgc tccgtcccgc gaagggcttc
    22861 ctgtcccgga ggtcgtaccg ggtcgaggtc gtctcggcga cgcgggactg ccggtatgtg
    22921 ctggtgccga actcctccga caccagccgc ctgcggcggg acaagcggcg gctcggcgtc
    22981 ttcacctcga ccggcgacgg gaaggactcg gccgtgtggg agaacggtga gcgccgttca
    23041 acggccgcac cggagccgta cgacgcggcc gtgggctacg ccctcgccgc cgcctacggg
    23101 accggagcgg aaccgatgtg gcacgaggcg ttggacgcgg tgacggaact ctggccctga
    23161 ggctccaccg cacggtggct gactgccact cctcttccgg caggccgagg aggcgttccg
    23221 tctcctgggg ggcggcaggg gcccccggag cggcgtcggg ctgcaaggtc gcccacctgc
    23281 cgggaccggg cgatgcggcg gatcgccggc tctgcccgag cgaggcgaag accgacatcg
    23341 acattcttga caacggctcc ggcaagacct gtcgccgggc cgatcagcaa aagaacgcct
    23401 tgtggtgcta ctcgatggac gtcgcgtcct tcggcacgat ggactttcct catggcaagt
    23461 ggtactgcct gtacgggtga tgggtgacag ccttccccac ttccgctatc acccggaccc
    23521 cgtggccacc gggtccatcc gcgcgtccgc cgaccggtgc gtgtgttgcg ggcgcagcag
    23581 gggatggatc tacacggcca ccttctacac cgcctgcgac gtcgacgggc ccttctgccc
    23641 gtggtgcatc gcggacggca gcgcggccga acgcttcgag ggtgacttca ccgactgcta
    23701 cgggctcgac gacgtcagca tggacgtcgt ccacgaggtc acccgacgca cccccggctt
    23761 ccacggctgg cagcagccgc actggcttac ccactgcggg gacgcggcgg ccttggtcgg
    23821 cgaggtcggc cacgcggaac tggcgcgaca cccggaagcc cttgcgcagc tcggcgactt
    23881 cgcacctcat ctgggcggtg atgccgctgc ggtgctgttc cgctgcacgg tgtgcggcag
    23941 ccatctcgcc tacgcggacg cctcctgagg acgtccacag ctacccgaag cagagttccg
    24001 cgtccttcgc cacgcagatg cgcaggactg tgatcagccg gccgacgtcc tcgacgtgtt
    24061 gccggacgtc gggatcgctg tcgtcggcca cgtgatcgtc gtggacttcc tcgagccgcg
    24121 gcagtatcgc cgcgcattgg gcaggtgtga gttccccatg gtcgtccggg tggtcgagca
    24181 gtggcgccaa cgtcgtgtgc acactggacc acgggcgttc tccaccgaag ccgtccatgt
    24241 cgtcgagcgt gaacccctcg atccgggcca gccatcctcg gaacgaggcg aaaccggagt
    24301 aggtccattc gacgtccggg ctcgtcacgt cgccgtcgcc cgggaagagc atcagcccca
    24361 tgtcacaccc ctctgtcggc ttccaacccg tgctggaccc gcggcacacg cgggagcacc
    24421 gaaggcatac ttcatcccca tgacgatcgc atacgagtgg cgcggtgacg tcgacaacgg
    24481 tgtcctcaac gccttgcacg ccgaagggtt cggcggggcc gtcgggatg
//
