MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 45.0 92.3 207.0 9.77e-67
AEE65494.1 response_regulator BGC0000223.5 PKS:Type II 42.0 93.1 190.0 2.31e-60
QCT05734.1 Tri1 BGC0001983.3 other:other 47.0 93.5 186.0 9.34e-59
ALJ99879.1 FlsR3 BGC0001904.2 PKS:Type II aromatic 41.0 95.1 183.0 1.7e-57
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 45.0 95.9 180.0 6.84e-56
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 44.0 95.1 171.0 5.96e-53
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 44.0 95.1 171.0 5.96e-53
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 44.0 96.3 171.0 9.21e-53
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 42.0 94.7 168.0 1.2e-51
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 43.0 95.5 166.0 5.38e-51
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 36.0 92.7 166.0 1.02e-50
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 42.0 93.5 163.0 8.08e-50
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 40.0 98.8 162.0 4.68e-49
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 35.0 95.1 160.0 1.25e-48
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 42.0 93.5 160.0 1.76e-48
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 42.0 93.9 159.0 1.14e-47
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 40.0 91.5 157.0 2.04e-47
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 36.0 92.7 156.0 4.83e-47
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 41.0 96.3 157.0 6.21e-47
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 41.0 92.3 153.0 4.71e-46
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 41.0 93.9 153.0 7.65e-46
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 41.0 91.9 154.0 9.69e-46
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 41.0 93.9 150.0 6.45e-45
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 37.0 96.3 150.0 9.55e-45
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 43.0 88.2 149.0 2.16e-44
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 41.0 94.3 148.0 5.26e-44
AAL15604.1 Sim1 BGC0000270.5 PKS 37.0 96.3 148.0 1.48e-43
AAK06808.1 putative_regulator_SimReg1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 37.0 98.4 148.0 1.48e-43
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 39.0 93.9 147.0 2.3e-43
ABB69091.1 hypothetical_protein BGC0000260.3 PKS 36.0 95.1 147.0 4.25e-43
AVO00817.1 May18 BGC0001661.5 PKS 39.0 95.9 145.0 5.55e-43
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 39.0 93.5 145.0 9.01e-43
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 41.0 93.5 144.0 3.47e-42
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 39.0 93.1 143.0 6.8e-42
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 41.0 93.1 145.0 7.83e-42
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 39.0 93.9 142.0 2e-41
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 38.0 92.3 142.0 4.92e-41
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 38.0 97.2 140.0 1.58e-40
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 39.0 95.5 139.0 3.3e-40
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 32.0 95.1 138.0 6.74e-40
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 36.0 94.7 138.0 6.93e-40
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 35.0 94.7 136.0 2.71e-39
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 35.0 94.7 135.0 3.83e-39
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 38.0 92.3 135.0 8.48e-39
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 40.0 93.1 134.0 1.39e-38
AEA29625.1 Por2 BGC0000409.5 NRPS:Type I 39.0 87.4 134.0 2.57e-38
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 41.0 92.3 135.0 2.64e-38
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 37.0 93.9 133.0 5.52e-38
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 38.0 92.7 132.0 1.09e-37
AFI57015.1 QmnRg3 BGC0000133.5 PKS 39.0 92.7 132.0 1.25e-37
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 36.0 93.9 132.0 1.36e-37
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 36.0 92.7 132.0 1.39e-37
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 36.0 92.7 132.0 1.39e-37
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 36.0 93.9 130.0 7.99e-37
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 36.0 93.9 130.0 7.99e-37
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 37.0 94.3 129.0 1.41e-36
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 36.0 92.7 128.0 4.88e-36
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 37.0 93.5 129.0 5.57e-36
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 35.0 94.3 128.0 7.17e-36
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 36.0 93.1 127.0 9.42e-36
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 36.0 93.5 128.0 1.23e-35
ABW71856.1 putative_regulator BGC0000303.5 NRPS:Type I 35.0 99.2 128.0 1.38e-35
ADB02841.1 AzicR3 BGC0000202.5 PKS 35.0 96.3 125.0 7.14e-35
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 33.0 92.7 123.0 2.28e-34
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 33.0 94.7 122.0 6.2e-34
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 38.0 92.7 120.0 4.46e-33
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 31.0 94.3 119.0 6.77e-33
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 35.0 94.7 119.0 1.45e-32
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 37.0 93.5 115.0 2.89e-31
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 29.0 93.1 114.0 7.62e-31
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 29.0 92.7 114.0 1.5e-30
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 33.0 94.7 113.0 2.01e-30
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 30.0 93.1 110.0 2.06e-29
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 29.0 92.7 107.0 3.1e-28
QUS58949.1 response_regulator_transcription_factor BGC0002123.3 NRPS:Type I+PKS:Trans-AT type I 33.0 93.9 105.0 2.81e-27
ASZ00168.1 putative_OmpR_family_two_component_response_regulator BGC0001785.5 PKS 37.0 76.4 103.0 5.83e-27
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 28.0 94.7 103.0 1.27e-26
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 48.0 48.8 97.0 5.43e-25
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 40.0 46.7 95.0 2.4e-24
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 37.0 55.7 80.0 2.87e-18
BAW35603.1 putative_DNA-binding_response_regulator BGC0002357.3 PKS+other:other 38.0 49.2 79.0 2.25e-17
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 39.0 46.3 81.0 4.25e-17
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 35.0 44.7 78.0 2.68e-16
ABK32284.1 Jer4 BGC0000080.5 PKS 39.0 47.2 76.0 1.76e-15
ADB02831.1 AzicR2 BGC0000202.5 PKS 36.0 51.2 73.0 2.35e-15
ABK32252.1 Amb4 BGC0000014.5 PKS 39.0 47.2 76.0 2.39e-15
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 30.0 88.6 73.0 3.82e-15
BAW35646.1 putative_two-component_system_response_regulator BGC0002356.3 PKS+other:other 38.0 48.8 72.0 4.13e-15
AWC08650.1 putative_two-component_system_response_regulator BGC0001662.4 PKS 38.0 48.8 72.0 5.72e-15
BCD33686.1 bacterial_regulatory_proteins,_luxR_family BGC0002448.2 NRPS:Type I 37.0 53.3 70.0 3.29e-14
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 36.0 44.7 70.0 4.47e-14
WP_030193597.1 response_regulator_transcription_factor BGC0002669.2 ribosomal:RiPP 31.0 71.1 69.0 1.12e-13
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 39.0 45.5 68.0 1.9e-13
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 33.0 51.6 68.0 1.95e-13
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 35.0 47.2 68.0 2.33e-13
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 36.0 46.7 68.0 2.36e-13
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 30.0 89.0 67.0 4.32e-13
QDF63356.1 KyaR BGC0002346.3 ribosomal:RiPP 32.0 86.6 66.0 1.1e-12
AUA09456.1 Transcriptional_regulatory_protein_LiaR BGC0002291.3 PKS 33.0 55.7 66.0 1.57e-12
ctg1_orf18 BGC0000053.5 PKS 32.0 58.5 65.0 2.21e-12
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 36.0 44.3 65.0 2.71e-12
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 35.0 47.2 64.0 8.08e-12
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 35.0 52.0 64.0 9.3e-12
QUQ72355.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 38.0 44.3 63.0 1.54e-11
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 31.0 76.0 62.0 2.08e-11
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 31.0 44.7 62.0 2.08e-11
ACI88882.1 AlnR5_two_component_response_regulator BGC0000195.5 PKS:Type II 28.0 85.4 62.0 2.15e-11
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 38.0 45.5 61.0 5.89e-11
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 34.0 50.4 60.0 1.46e-10
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 31.0 45.5 59.0 2.51e-10
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 31.0 45.5 59.0 3.44e-10
AAP03103.1 putative_2-component_system_response_regulator BGC0000874.5 other:other 32.0 76.8 58.0 8.96e-10
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 32.0 51.6 58.0 9.46e-10
BAW27696.1 regulator BGC0001764.4 NRPS:Type I 33.0 45.9 57.0 1.85e-09
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 34.0 52.0 56.0 3.17e-09
BBA21064.1 putative_two-component_response_regulator BGC0001740.5 NRPS:Type I+PKS 44.0 30.5 53.0 6.83e-09
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 28.0 68.3 55.0 7.07e-09
ACR33059.1 response_regulator BGC0000495.5 ribosomal:RiPP:Lanthipeptide 29.0 92.3 55.0 7.69e-09
ABD65961.1 two-component_system_response_regulator BGC0000341.5 NRPS:Type I 28.0 97.2 55.0 7.93e-09
ARF06225.1 LuxR_family_transcriptional_regulator BGC0001593.5 NRPS:Type I 33.0 50.0 55.0 1.24e-08
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 32.0 50.4 54.0 1.4e-08
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 28.0 88.6 53.0 3.76e-08
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 28.0 98.8 52.0 9.33e-08
MCG7203797.1 response_regulator_transcription_factor BGC0000248.5 PKS 29.0 47.2 52.0 1.02e-07
EAW09112.1 sensor_histidine_kinase/response_regulator,_putative BGC0000983.5 NRPS:Type I+PKS:Iterative type I 28.0 53.7 53.0 1.04e-07
AFW04580.1 transcriptional_regulator BGC0001783.5 other:other 30.0 45.5 52.0 1.08e-07
ACX83628.1 putative_two-component_response_regulator BGC0000221.5 PKS 27.0 63.8 51.0 1.23e-07
ATD51275.1 two-component_system_response_regulator BGC0001650.4 NRPS:Type I 34.0 50.8 51.0 1.59e-07
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 30.0 45.5 50.0 4.21e-07
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 33.0 45.9 50.0 5.79e-07
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 30.0 49.6 50.0 5.93e-07
BBD82049.1 LuxR_family_transcriptional_regulator BGC0001920.4 ribosomal:RiPP 33.0 45.9 49.0 1.06e-06
AXG46174.1 two-component_sensor_histidine_kinase_BarA BGC0002713.2 NRPS:Type I 30.0 45.5 50.0 1.33e-06