LOCUS       NZ_JMLS01000021        23939 bp    DNA     linear   CON 10-FEB-2024
DEFINITION  Paenibacillus sp. UNC451MF BP97DRAFT_scaffold00018.18_C, whole
            genome shotgun sequence.
ACCESSION   NZ_JMLS01000021
VERSION     NZ_JMLS01000021.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Paenibacillus sp. UNC451MF
  ORGANISM  Paenibacillus sp. UNC451MF
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 167208)
  AUTHORS   Dangl,J., Huntemann,M., Han,J., Chen,A., Kyrpides,N., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-2014) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Paenibacillus sp. UNC451MF
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi0054671
            Gene Calling Method               :: Prodigal 2.5
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2014-04-01
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/10/2024 01:27:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,772
            CDSs (total)                      :: 6,708
            Genes (coding)                    :: 6,634
            CDSs (with protein)               :: 6,634
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 3 (5S, 16S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 18 of 74
            Pseudo Genes (incomplete)         :: 59 of 74
            Pseudo Genes (internal stop)      :: 15 of 74
            Pseudo Genes (multiple problems)  :: 15 of 74
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:46:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 85791
            Orig. end                         :: 109730
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JMLS01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..23939
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..23939
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23939
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13939](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13939
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(87..102)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     misc_feature    441..450
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.44"
                     /tool="antismash"
     gene            complement(813..1121)
                     /locus_tag="BP97_RS0120950"
     CDS             complement(813..1121)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP97_RS0120950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028550857.1"
                     /transl_table=11
                     /translation="MRHLKRFICVTLLLIAFILPTTAFASNGNSNSQNHQNNPKNNNNQ
                     SWEQYFSSFFSGNKGNKDDDWKHYYDNNKDFKDWYDKHKNDCPDGESDDIWKKWFCY"
     gene            complement(1261..4011)
                     /locus_tag="BP97_RS37055"
     CDS             complement(1261..4011)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024627.4"
                     /locus_tag="BP97_RS37055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_051620841.1"
                     /transl_table=11
                     /translation="MDGKLKKIKNAQNEYMYPITVSDAVYVDPETSLKTKLAELDANLG
                     NPNSYVIELDKWGIHSDGSESAATTKGINDALSWAKSSGYNHVLLPSGTYSLKIDPNGI
                     AIYMLSGIHFEMKDDCVLQLEGNSSPSYRIIHFDQIDHAKVSGGTIIGDKASHQYEMYV
                     KFVRGGVNADGSLNDNPNFIRSEVIDRYQNPGLLSTFRLWSINGITTTTYSFYQYKDSV
                     SKDTLVNFRTNGEFAPAAPTGRGWFDTIDQDNKMVFVIDITSSPLTNEQISQISAKVDN
                     SYYTHEGGYGVAVFSSNYIEVQGIEISNCTGDGIFVGISVRYEDPSQYTQEEMGQHIYI
                     HGCDIHHCRRQGMSLCGSNDVFVANNTIHHIGYADDGVTTDFRNGTAPMFGIDVESMVG
                     ESNIPYKSIYLNQDGLETNYRIYIYNNYIHHNAKGHFVNADGTQITLQNNTFEAYNVGA
                     ISSYPNQWYIKYLNNTFIQCTLVVKGNNVVNGGVFNKANLNLMDVQGALIDNCQIKDGL
                     FYGSSIYGYFGMPSAVNIATGTFAYTAPHGMGNGAQICFEQWFGKVPTGISVDKVYYTV
                     NITSTSFQVSETKGGSPVMITDAGVTGFNISRYNYGRCYISNITVETDWNDTTGSKGFN
                     TLVAGAVIHNVTVKNCPVSIKAPDNYVGRPNVIVGLTLLESGGNLQASDLSNLKVMKVR
                     TKALGGDLTLGSTTAYSRVNIDSGLFQGIQVNFEEAYLNNGTFINAIVYKQDHSNRSIL
                     SNSYLENTSLSLHWLTMDKSMIITKCLFNNVTVDASSSVKMIDNVDVNSGLSDNRMNAL
                     PVSGKYTLGQIIYNSTPKPGGYVGWICTTGGYATNQAWAASKAFSLGYRIQSGGHVYEV
                     TTAGTSGSVPPVFPTSSGSTITDNTIVWKEIGLLAVFNNFGPIST"
     gene            complement(4051..4890)
                     /locus_tag="BP97_RS0120960"
     CDS             complement(4051..4890)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012271.4"
                     /locus_tag="BP97_RS0120960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="WP_028550858.1"
                     /transl_table=11
                     /translation="MADQNSIVYYEDWSDLEPVNVINTVPPDNVTNLTASKVQGNLVTL
                     SWTASSSNDVTGYGIYNGTVYVGSTASTTYDVTGLNPETTYTFAVKTINKDGLTSNGAS
                     ISVTTPILTYALSMNGTTDYVQTPSLSFDTVIMDILVDPKSMVYNSYLDATRGIPQSAF
                     GRNSSGYDYLQSAWKSVSINGVDKTAGANISAIVPTQQRITVTVVLKSPGKSILVLFAN
                     QLGSIPMKGILYSVKIMSGGVVTALYDFTKPFTGTAVPDSSGNNQTAKLQGGTWING"
     misc_feature    complement(4879..4892)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     gene            5208..5969
                     /locus_tag="BP97_RS0120965"
     CDS             5208..5969
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216: exopolysaccharide biosynthesis domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014732.4"
                     /locus_tag="BP97_RS0120965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="WP_028550859.1"
                     /transl_table=11
                     /translation="MEINLREYFMIIKKRLWLVVTIVFICTALTAVYSSMNYQPVYMAA
                     TKLIVNKTSEKDQLGREQIDFGAIGVNIGLINTYKEIIKTPAIMDKVVQRYPDLNLTAE
                     QLIAMTNVAGLHDTQVMTIVATHYSYEKAVNIVNAVSEVFQSEIPKIMKVDNITILNRA
                     KMQDYPVPVNKKSNQYIILSFAASLVVAIGIVLLLDAMDDTLKTEEDVRQMFAVSTLAC
                     VPRMKGKDLKSSKGRKSRKKVGEVHHVNTIH"
     gene            5950..6618
                     /locus_tag="BP97_RS0120970"
     CDS             5950..6618
                     /EC_number="2.7.10.2"
                     /GO_function="GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216: exopolysaccharide biosynthesis domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01007.1"
                     /locus_tag="BP97_RS0120970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="WP_028550860.1"
                     /transl_table=11
                     /translation="MSIPSTKSEIMMETNPGSLASESYRSLRFNMETFALDQGIQTVSL
                     TSAGRGEGKTTTALNVATAYAQIEKRVLLIDADLRNPSLHYTFGGDNSKGLSSYLMHQS
                     TLDEIIAPTNIQNLSVIPAGAVPTNPAELLASKAMKQLLEEVKPRYDMIFIDSSSVLSL
                     TDGKIVAAQCDGVLLVVDHGKLKRQAAKKVKEELELAKAKLLGVVFNKVNPKNAELFLY
                     "
     gene            6683..7960
                     /locus_tag="BP97_RS0120975"
     CDS             6683..7960
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF027890.4"
                     /locus_tag="BP97_RS0120975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_028550861.1"
                     /transl_table=11
                     /translation="MRRKRVGLHRRRVRTICILALSFVIIAGCSETIPISSDGNAAAQA
                     QALKSVKVSKVTKQKIGDPLVHAADVQSSVQFDIVAKAAGDIEAILKARGDVVQEGDVI
                     ARLNSSEAKFEKEKAALAVQTVQDAIVKAKERAKKEMDNQKRDLNDSIKKQEQALNDLT
                     RNYNKTKNDYEVGLATKVQVYQMEVQLRNSRTDLELLKDKLARLEPVDTTSELQTQLKT
                     TQMAQLQVEQSLTYLEVKAPVSGVLTELPFEVGMSIPAGTKIGLIQKLDPIKLKAQLSE
                     EESKFATGKSEMTYYMQGAAQKSKARISFLSKVINPDTKAYEINLDVPNKDMTLKPGMK
                     VWLQLTEDQDQIVLTVPTYSVVKEGQDSFVFVLTGDTVEKRLVQLGRLNDSTQEILSGV
                     KEGEQVVVSNPGQLKDKEQVQRTAVE"
     gene            7987..9699
                     /locus_tag="BP97_RS0120980"
     CDS             7987..9699
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP97_RS0120980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028550862.1"
                     /transl_table=11
                     /translation="MRMKWKPTLLMTLLIFSLLIPSASFLAIAEEGVPVTKEYSLTSTV
                     KAAVKSILNEQVAEGTRIGAVVRLTNEGTRLTRVPDYEVRVKAEDGVLYTLRPSAENVI
                     AIQPKETVELSYMIVIDREDTFSLSEISWVDVDEFVSPRSEKMIVSIPISSIEWRGDIA
                     VFSDALATHSWGENMTIQVLSTSLEYKPVSLSEQNTPQGPKTIVGLLATNKSDKKKAIP
                     DFRVNGRSDKKVYTGVRLEKDPIVLGPGEQQYIHYAIPAGKKEELIGLTVLTPESFATD
                     DKTKIEYLIGQFNVALPQDGGVVSEADQPKMYVWNSPIQFDPLNNVVQPEVSVSMVTLQ
                     MHESVGGGFKAAVAKFKLTNRSDRPMPVPKFQAQLMGVGGTKYTGTRQTAVVETLIPNV
                     SYVMYYSFVLPSNEKGEQLTMDILDSESVAPYNIPIATFKTMVKKEKSEDTGLSFYPFN
                     VKINSWKSEVFYGSARESFPYSYKLSIDMDVSLQEEVVVDQNFPKLKVELVDDKGKVIG
                     SKTLPFIGENRVATGTQTVNMDSVLYEFSNSLRVYETIDTPYGQADRLIATLQ"
     misc_feature    complement(9934..9948)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.38"
                     /tool="antismash"
     gene            10001..11941
                     /locus_tag="BP97_RS0120985"
     CDS             10001..11941
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272773.1"
                     /locus_tag="BP97_RS0120985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_028550863.1"
                     /sec_met_domain="GATase_7 (E-value: 7.5e-21, bitscore:
                     67.5, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 3e-22, bitscore:
                     72.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAITGIYHFTQEPIPTEHGLTLMSGLQQFPSDSIHTWRNEHVFL
                     GCHAQYITPESAHELLPYYDTERQLVITADAIIDNRESLFQLLQIDYGRRSTITDSELI
                     LLAYDKWEENAPQYLVGDFAFMIWDLRNGRLFGARDFSGSRTLYYYHDHQRFAFCTTIQ
                     PLLSLPYTKTTLNEQWLAEYLAIIGMVDVVDASTTVYRDIAQLPPSHSITIAGSKVTLK
                     RYCTLTSRERLKLKSNEEYIEAFQEVYQEAVTSRLRTNRQVGAQLSGGLDSGSIVSFAV
                     KELSKSGKTLHTFSYVPPSDFEDFTPAHILTDERPFIQSIVKHVGGMKDSYEDFAGRDP
                     YTEMDSFLSTMEMPYKFFENSFWLKGMFEKAQEANVGVLLNGGRGNLSISWGSAIDYYA
                     TLLKRLQWVRLAQELHSYSKNVGGARLRRLPDVARTAFPIMDRLFPTSEPFAYPMLINP
                     DFAKKTDVFNKLKQHGMDQSGWFSSPNLFEQRKSHFEELFHWNASNTLATKLSLNYGIW
                     KRDPTNDLRVIRFCLSLPEEQYVQNGLDRALIRRATKTLLPDNVRLNQSIRGVQGADWV
                     HRMIPHQSALLVELDEMSADPTIFELLNGPVIRRAIDKVRAGLRPEDATNAELKFLMRG
                     IVVYRFLKKWT"
     gene            11957..12112
                     /locus_tag="BP97_RS40275"
     CDS             11957..12112
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160858.1"
                     /locus_tag="BP97_RS40275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_156043271.1"
                     /transl_table=11
                     /translation="MKKAWQKPVLEVLDVNQTMASTVYGDFTDEAYVPGKPVDPNNPST
                     WKRFNS"
     gene            12258..13184
                     /locus_tag="BP97_RS0120995"
     CDS             12258..13184
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160859.1"
                     /locus_tag="BP97_RS0120995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldolase"
                     /protein_id="WP_028550864.1"
                     /transl_table=11
                     /translation="MLQTENKIVYSAFGLRISSEIPLPELPHISEPSDELDIEIRNGDI
                     GRFADQLFATPFMHVVDEGAVMFYVPDTAYYSIRDGRFITVSPVQGADEDLIRLYVLGT
                     CMGALLMQRGILPLHGSAVAIQGKVYAFVGDSGAGKSTLASAFLSQGYSLVSDDLIAVT
                     LSKEDQKPMVTPSYPQQKLWQDSLNHLGMSSSDLRSIYGREDKYCIPVASNYVTSPLPL
                     AGVIELVKTENQLQVVRIEKLDRLQTLFYHTFRPFLIPRLGLMEWHFQSSSVIANQISM
                     YQLSRPESQFTAPQLVNLILDTLSMEA"
     gene            13188..13487
                     /locus_tag="BP97_RS0121000"
     CDS             13188..13487
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594720.1"
                     /locus_tag="BP97_RS0121000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_028550865.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.9e-26,
                     bitscore: 83.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.5e-18, bitscore: 59.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 1.1e-07, bitscore:
                     25.5, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQNHKIGMQDCFSQVTGNIVSDMGGEKVMLSIANSKYYNLGEVG
                     GEIWNCLTEASSVSAEQIVAVLMSQYDVEQVECEQQVVSFLEHLLEEGLIKWAS"
     aSDomain        13233..13475
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BP97_RS0121000_Stand_Alone_Lasso_RRE.
                     1"
                     /evalue="9.40E-27"
                     /identifier="RREFam002.1"
                     /label="BP97_RS0121000"
                     /locus_tag="BP97_RS0121000"
                     /protein_end="96"
                     /protein_start="15"
                     /score="83.9"
                     /tool="antismash"
                     /translation="VTGNIVSDMGGEKVMLSIANSKYYNLGEVGGEIWNCLTEASSVSA
                     EQIVAVLMSQYDVEQVECEQQVVSFLEHLLEEGLIK"
     aSDomain        13272..13454
                     /aSDomain="Streptide_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM enzyme in a
                     streptide-like cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BP97_RS0121000_Streptide_RRE.1"
                     /evalue="2.10E-08"
                     /identifier="RREFam022.1"
                     /label="BP97_RS0121000"
                     /locus_tag="BP97_RS0121000"
                     /protein_end="89"
                     /protein_start="28"
                     /score="25.5"
                     /tool="antismash"
                     /translation="VMLSIANSKYYNLGEVGGEIWNCLTEASSVSAEQIVAVLMSQYDV
                     EQVECEQQVVSFLEHL"
     gene            13475..13939
                     /locus_tag="BP97_RS0121005"
     CDS             13475..13939
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020061974.1"
                     /locus_tag="BP97_RS0121005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_028550866.1"
                     /sec_met_domain="PF13471 (E-value: 1.6e-26, bitscore: 85.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIVSKVKKFLQLDMATMLLIAEAIFYLGWARMLVSIPFAKVAPS
                     LGAHMQETSNSERRDDIESLIKVHDIIRVMSQHTFWESKCLVRAIAALKMLERRHIEST
                     LYLGTARDEQRKMIAHAWLRSGPFYITGAEEMERFQVVGTFAKRISDKGN"
     gene            13951..15138
                     /locus_tag="BP97_RS0121010"
     CDS             13951..15138
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002014444.1"
                     /locus_tag="BP97_RS0121010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_028550867.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 6.8e-68, bitscore:
                     222.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAGYHMDVSLFPNELELMLSLIKTEEVNIGDTSYNKGLTDIDWA
                     FFLELATHHRVFPTLYTKLKSMNEPGIPPYVMQSLRNDYQQNTFQMLHLSAEMDTICKL
                     LSDSGIRSLVLKGPVLAADLYGDISQRTSGDLDILIPIEELEHAEQLLVRQGYEKDEYI
                     QTVLNDWKWRHHHITFFHHHKGIKVEIHWRLGPGPGKEPSFQALWERRRTSAITRHPVY
                     YLGREDLFLFLVSHGARHGWSRLRWLLDIDRMVKQSMDVRKLRRLLKQYEHLHIGAQAL
                     ILASQLLHTPLTEEMRTLAQGQRARNLAQEALFYIRQMINLHTDPIPYEVSEYHKKHLF
                     SLMSNHRKLLFILNFFYPYPEDANTLALPKYLHFLYFPLRPFLWVWRKTKKVALS"
     gene            15150..16964
                     /locus_tag="BP97_RS0121015"
     CDS             15150..16964
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096316.1"
                     /locus_tag="BP97_RS0121015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_028550868.1"
                     /transl_table=11
                     /translation="MEHVLYYTRKLHAYAGKVLYMNLLGMTLIGLLDGIGIFLLIPLLS
                     VSGLLSIQTSAIPFMGMLDFLKDVSRPVGLLLILGLYFLLVVGQAAIQRNLSLRDVQIH
                     AGFVNHVRMETYQALLQANWSFFIKKRKSDLINSMTNELARVTNGTYVFLQLLASLVFM
                     VIQIGIALWLSAKMTLFVLACGLIMALFSRTFIRKFRMLGTQTSDVARSYIGGITDHFN
                     GIKDIKSNMLEPSRYRWLQNWSVTVAQERYEQAKLGSQSQFYYKAASTLIIAVFIYFSV
                     TLFQTQGEQLLLIIMIFSRLWPRFTGIQSNLEQIAAAIPAFTSLTELQKECMETREVSI
                     GTLDYNQVKPLRIQEGIECKDIYFRYDKNSPIYALEHIQLSIGSNQMTAIIGRSGAGKS
                     TLIDIIMGLLQPDHGQVLIDGVPLTKDNLLRLRKAISYVPQDPFLFNGTIRENLLLMNP
                     NSTEEELWEAIQFAAGEFVSRLPQGLDTLIGDRGVRLSGGERQRLVLARAILRKPSILV
                     LDEATSSLDTENEAKIQEALERLKGTMTIIVIAHRLSTIRNADQVIVLDEGAIVQRGGF
                     NQLAKERGKVFAHLLGSQFQDSTMISQK"
     gene            17122..17871
                     /locus_tag="BP97_RS0121020"
     CDS             17122..17871
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016127636.1"
                     /locus_tag="BP97_RS0121020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_036746304.1"
                     /transl_table=11
                     /translation="MANHHPTRQIPRVIHYCWFGGKEKPDIVKRCIQSWQQHLQGYEIF
                     EWNEESFDINTNLYTKQAYEAGKFAFVSDYVRVHALYHFGGIYMDTDVEVFKSFDDLLH
                     HASFWGFEQENYIATSTIGAAKGNKLIQRFLESYDGKSFIKADGTHDDLTNVAIVTKML
                     EELGLKPDGQYQEMEGIGVFYPQTYFSPYDYINCRKFITENTYAMHHYHKSWLSPKARL
                     KSKVKTIAAQWIGGDNIARLRKLVSKM"
     gene            17881..19074
                     /locus_tag="BP97_RS0121025"
     CDS             17881..19074
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002184570.1"
                     /locus_tag="BP97_RS0121025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_028550870.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.6e-30,
                     bitscore: 98.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNILVASYDMEVGGVERSLASMLEHFDYEQYSVDLMLHRHKGDF
                     MNLLSPKVRLIDEIPEYATFRKSIAETIKDRHYRIGISRVASRVSAGLLGKIRNMAEPG
                     YYQMQLMWKYALPYLPSLEKPYDVAISYLWPHYFVAEKIHARQKIAWIHTDYSNIDTDI
                     SLDLRMWNQFDLIVAVSDACQASFLGKYPSLEPKVIVMENITSPEFIRTMANKEAAEPI
                     ESDSRFTLITVARLSHAKGIDNAVRALKLLKDKGYDDIAWYVVGYGGDEAMIHQLIAEH
                     KLEDRFILLGKKTNPYPYMKAANLYVQPSRYEGKAVTVTEAKILGKPVLITNYPTAGSQ
                     VDNEVDGVICDLNVEGIAEGIERMYKKQELRVQLMDNIKDKDYGNSCELEKLYRLIG"
     gene            19121..20155
                     /locus_tag="BP97_RS0121030"
     CDS             19121..20155
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081477.1"
                     /locus_tag="BP97_RS0121030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_028550871.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-40,
                     bitscore: 131.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIKVSVIVPVYNAEQYIAHCIESLLNQTLEECEFIFVNDGSKDQ
                     SGQVIEEYSKTDSRIKLVHQSNQGVSAARNAGLQEATGTYIGFVDADDYVDKDMYEVLY
                     NTAIESDYDVVISNFESEIEGHKVITTYPFPLGTVLKKDYIEQEVLTYFLKSDQLNTVC
                     SKLYKNKRIQDYKVKFPEKVALGEDGLFNMQFFRHADRIQYIDYTGYHYREVVGSATRN
                     ILEKDYFKRALEVYTLDIPEMYLTTLDKMRIQQLRSIKLINSVMSYIYVYFKSSNEISF
                     RQRMKYVNNMINDPCVREALPYFYSEMYTSLGTYEKFLADMIRKRFTLGLFVATTYSRL
                     RNKA"
     gene            20197..21357
                     /locus_tag="BP97_RS0121035"
     CDS             20197..21357
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016132437.1"
                     /locus_tag="BP97_RS0121035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="WP_028550872.1"
                     /transl_table=11
                     /translation="MKIMMFAHDGSLNRGCEAIVRSSTHIIKEKIQGAKVYLASGKPDT
                     DKVISKLDGIYDGSARGIKKFSYDWFLSAVKVKLFQDETYALGKIHNNIVKHIPNMDVC
                     LSIGGDNYCYGEQPGWYEINRRVKASGKKLVLWGCSIGEEDMSDRKLQDLRLFDLILAR
                     ETLTYDMLVAKGLTNVKLCADSAFTMEKEELELPAGWQEGNTVGLNFSPLVWKKNKESR
                     TAVKDLIQHILDTTDMAIALTPHVMEGGNNDYEVLQQYYEEFKHTHRVILLPNHLTAIQ
                     YKGYISRMRFFIGARTHATIAAYSNYVPTMVLGYSVKSKGISKDIFGEEKLVLSIDQIS
                     NSFMLKAKFDEMIKEEGLIKQKLQASIPRIKKMSYKAVEYLDKLVQ"
     gene            21373..22563
                     /locus_tag="BP97_RS0121040"
     CDS             21373..22563
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016130943.1"
                     /locus_tag="BP97_RS0121040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_028550873.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.3e-28,
                     bitscore: 93.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNLLFVMPSLTAGGGEKSLVNLLSQIDYKAYNVDLFLFSQTGV
                     FINSLPKEVNILGFPNKYNIYTKGLKKSMEEFLAKGQVTLAYSRLMFTVMNRVIRNTDF
                     SEQFTWKYQRKSLDTLEKVYDAAIGFLEKSSIYFVVDKVKARKKIGWIHTNYSDSGMRH
                     HYDDPYFKQLDHIVTVSEECAKSLSDHFLHLNNKIKVIYNIVSPKMIHHLSNEDIDEGT
                     IFDTEYTNIVTLARLSHEKGIDLAIESCKLLVGKGHNIRWYVLGDGQDRESLESLIEKH
                     QLGPYFKLLGVKENPYPYIKKADIYVQPSRYEGKSIAIDEAKILQKPIVVTNFETAKDQ
                     IQHGINGVIVDLSPAGISQGIEKLMEDIPLKNRVICNLAIEKLGTEGEIRKLYEIL"
     gene            22582..23763
                     /locus_tag="BP97_RS0121045"
     CDS             22582..23763
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002184575.1"
                     /locus_tag="BP97_RS0121045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_028550874.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 5.3e-29,
                     bitscore: 94.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRVLFVMNNMRCGGAEKALISLLETMDYSAYEVDLFLFKHDGI
                     FMNQIPESVHLLEEPAEYQYYDMSIKRAILDCVRKGKLHIALFRGLAGVIFKSEKNRVR
                     CEQRVWKYISKSLKNIDKPYDIAVGYLEKNPIYFCIDKVKAHKKIGFIHNDYDKLGMDP
                     ELDRSYFDKLDHLVTVSEECGHVLKNRFPMYQQKVDVMYNIVSPAAISKLSQEQSEWDD
                     RRMKLVSVGRLNHQKGFELAVETCKELVHNGYPVTWYVIGEGEERGMLEKLIAANNLQD
                     RFVLMGLKENPYPYIKEADIYVQPSRFEGKSIAIDEAKILHKPIVVTNFSTAKDQINDR
                     ENGLIVEMNSTSLFHAIKSLIDDEELRRKLTLNLSREKLGTESEIHKLYELFA"
     misc_feature    23830..23844
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
ORIGIN
        1 acgcttaccc aaacagctcc gttctcccaa ttaacggcag tatggtacaa tccggaaacc
       61 ggtgatttaa gctttgtgcc tgccctattt gcaactgtaa atggaaaaac agaagcggct
      121 gtaaaacgtg cgggcaacag catttatgcc attgtgaagg catccaaaac gtttgctgac
      181 ttgcaagggc attgggcaaa aggtgaagct gaattgctag cgtccaaggg agtcgttaac
      241 ggtacttccg aaacaacctt tgcacctgac actcctatta cacgcgctga atttgcgaca
      301 ctgctcgtaa gatctgcagg actttctacg gaatccacag caaaattctc ggatgtaaaa
      361 tccgaatggt atgcgggtta tgtaggagca gcttcaaagg cagggcttgt agatgggttt
      421 gaggatggta cgttccaacc gaacgcgacc attactcgtg aacaaatggc aaccatgatt
      481 gcccgggcaa tcaagctcat gggcaagaac agtgatccga atgccaacaa gcttgaggca
      541 tttgcagata gtaaggacat ttccggctgg gcaaaggatg ctatagctgg agcggttaac
      601 gcagggatta ttaacggtgt aaccgataag acctttgctc caagcagcaa ggcaacgcgc
      661 gcagaagccg ctgttatgct caagcgtctg ctgcagtatg caggattcat gaacgagtag
      721 catctagata acagttaagg ggttatcctt ataagtctga tgacttatgc aggataaccc
      781 cttttttaaa taagcaagaa ggaggctagc tattagtaac aaaaccactt tttccaaata
      841 tcatcggatt cgccgtccgg acagtcattt ttgtgcttgt cataccaatc cttgaagtcc
      901 ttgttattgt cgtaataatg cttccaatca tcatccttgt tccctttatt tccggagaaa
      961 aaggatgaga aatattgctc ccagctctgg ttgttattgt tctttggatt gttttgatga
     1021 ttttgactgt tggaattgcc gttggatgcg aaagctgttg taggaagtat gaatgcaatg
     1081 aggagcaggg taacacaaat gaaccttttt aagtgccgca taactgctaa ccctccttct
     1141 atgaataaat tgtaaagaaa tgttcgttat taagaatcat acatcaaata aggatgtttg
     1201 agaatgtctt tttttaaaga ttaaaaaata aaaaagctgc cgtaaacggc agcgattcta
     1261 ctaagtgctt atggggccga aattgttgaa tacagccaat agaccgattt ccttccatac
     1321 gattgtatta tctgtgatgg tacttcctga tgatgtaggg aagactggag gtacggaacc
     1381 cgatgtgccg gcagtggtca cctcgtatac atgccccccg gattggattc gatatcctag
     1441 agaaaaggct ttggaagcgg cccatgcctg attagtagcg tacccgcctg ttgtgcatat
     1501 ccagcctaca tagcctcccg gcttaggagt ggaattataa atgatttgcc cgagagtgta
     1561 tttgccgctg acaggtaacg cattcatacg attatcggaa agtccggaat taacgtcgac
     1621 attatcaatc atcttaacgg aggagctggc atccactgta acattattga aaagacattt
     1681 cgttattatc atcgacttat ccattgttag ccaatgaagc gacaaagaag tgttttccaa
     1741 gtaactattg cttaggatcg atcggttaga atgatcctgt ttgtacacga tcgcattgat
     1801 aaaggttccg ttgttaagat aagcttcctc aaaattgact tgaatccctt gaaagagacc
     1861 gctgtcgata ttcactcttg agtaggctgt agtggagcct agggtcagat ctccgcccag
     1921 tgcttttgtt cttactttca tcaccttaag attgctcaag tcgctagctt gaagattacc
     1981 gccgctctca agtaaagtga ggcccactat gacattaggt ctgccaacat aattatcggg
     2041 cgctttgata gacactggac agttcttcac ggttacatta tggattacgg caccggcaac
     2101 tagcgtatta aagcctttac tccctgtagt atcattccag tcggtctcaa ccgttatgtt
     2161 ggaaatgtag catctgccgt aattgtagcg ggaaatattg aagccggtaa cacctgcatc
     2221 tgttatcata acagggctcc cgcccttggt ttcagatact tggaagctcg tggatgtaat
     2281 attgacggtg tagtacactt tatcgacact aattcccgta ggcaccttac cgaaccattg
     2341 ttcaaagcaa atttgagctc cgttgcccat tccatgaggt gcagtatacg caaatgtacc
     2401 tgtagctata ttgacagcag aaggcatccc gaaataaccg tagatgctcg acccgtaaaa
     2461 caagccgtcc ttgatttggc aattgtcgat aagagctcct tgaacatcca ttagattcaa
     2521 attggctttg ttgaacacgc cgccgttaac gacattattt cctttcacaa ctaacgtgca
     2581 ctggatgaac gtattattga gatacttaat gtaccattga ttaggataag agcttattgc
     2641 tcctacgttg taagcctcaa aagtattgtt ctgtagtgta atctgagttc catccgcatt
     2701 aacaaagtgt cctttggcat tatgatgaat atagttattg taaatgtaaa tccgataatt
     2761 tgtttccagc ccgtcctgat tcaaataaat gcttttgtaa ggaatattgc tttcgccgac
     2821 catcgactcc acatcaatac caaacatagg agcagttccg ttccgaaagt cggtcgttac
     2881 tccatcgtca gcatatccaa tatggtgaat cgtgttatta gctacgaaga catcattgga
     2941 accgcatagc gacatgcctt gtcgtctgca atgatggata tcgcagccgt gaatataaat
     3001 atgctgtccc atctcttcct gggtatattg ggagggatct tcataacgga cgctgattcc
     3061 tacaaagata ccgtcgcccg tacaattcga tatctcaatt ccctggactt cgatgtaatt
     3121 ggagctaaaa acggcaacgc cataaccccc ttcatgagtg taataggagt tatcaacctt
     3181 ggcgctaatt tgcgaaatct gttcatttgt gagtggcgat gatgtaatat cgatgacgaa
     3241 taccatcttg ttatcttgat ctatggtatc gaaccatcct ctacccgtag gagctgctgg
     3301 agcaaattca ccattggtac ggaaattgac caaagtgtct tttgaaacgc tgtctttata
     3361 ttggtaaaag ctgtacgtgg ttgttgtaat accgtttatt gaccagagtc tgaaggtgga
     3421 taaaaggcca ggattttgat agcgatcgat cacttcactt ctaataaagt tggggttatc
     3481 attcaaagaa ccgtccgcat taaccccgcc tcttacaaat ttgacataca tttcatattg
     3541 gtgagatgct ttatcgccga taatggttcc gcctgaaact tttgcgtgat cgatttgatc
     3601 aaaatgaatg atacgataac taggtgacga gtttccttcc aactgcagca cacagtcatc
     3661 tttcatttca aagtgtatgc cgctcagcat ataaatagcg atgccattcg gatcaatctt
     3721 tagagaataa gttccactag gtaatagtac atgattatac ccgctggact tggcccaaga
     3781 tagcgcgtcg ttaattcctt tggtcgtagc ggccgattct gatccgtcac tatgaatacc
     3841 ccatttatct aattctatga cataagaatt aggattaccg aggttggcat ccaactcggc
     3901 aagtttggtt tttaagctgg tttcgggatc tacgtatacc gcatccgaaa ctgttatcgg
     3961 atacatatat tcgttttggg cattttttat ttttttcagc ttaccatcca ttattgcacc
     4021 accccccgcg ttagtttgct gtcaagtact ttatccgttg atccatgttc ccccctgcag
     4081 cttggctgtc tgattattgc cgctcgagtc gggaacggct gtccctgtga acggtttcgt
     4141 gaaatcatat aaagcagtca cgaccccacc cgacattatc tttacactgt aaagaattcc
     4201 tttcatagga atgctcccaa gctggttcgc aaataggacc agaatggact tgccaggtga
     4261 cttaagaaca accgtaacgg ttattcgttg ctgggtagga acaatggctg aaatatttgc
     4321 tccagcggtc ttgtctactc cattgataga taccgacttc caagcggact gcaagtagtc
     4381 gtaccctgag ctgtttcttc cgaaagcaga ttgaggaatt cctctagtgg cgtctagata
     4441 ggagttgtaa accatgcttt ttggatctac caaaatatcc ataataactg tatcgaaaga
     4501 gagggaggga gtctgaacgt agtcggttgt cccattcatg gacagggcat aagtcaatat
     4561 aggcgttgtc acagatatac tggcgccatt gctcgttagt ccatctttat ttatagtttt
     4621 tacggcaaac gtataggttg tttctggatt taatcccgtt acatcatacg ttgtggatgc
     4681 tgtgctgcca acatagaccg ttccattgta tatgccatat cctgtcacat catttgaaga
     4741 gcttgcagtc catgataacg taaccagatt gccctgtact ttggatgctg tcagattcgt
     4801 aacattatca ggaggcaccg tgttgattac atttacgggt tctaaatctg accagtcctc
     4861 ataataaaca atcgaatttt gatctgccac gaggatcacc cctttgtaat cttttatata
     4921 gattatgttt tcatagatgg aatggtgaat tattatttca tgcaaaatgg tattctaaag
     4981 agaacaaaat agcagtagaa cgggttctag cctttttgta tcttcttgtc gggtaagaat
     5041 taattcaatt ctgtgaaata tgatacaaaa tggatcaaac agcgtaaaat ccggtgttga
     5101 cacgatacaa aaagtgtcat aaagtattga ctataggcaa tgatacaaaa agtatcaacg
     5161 gctttggggc aaaaaatgat atgactactt ttcgctgggg gagaattatg gaaattaact
     5221 taagagagta ttttatgata ataaagaagc gcctttggct agtcgttacc attgttttta
     5281 tatgcactgc actaacggct gtatacagca gcatgaatta tcagccggtc tacatggctg
     5341 ccactaagct gatcgtcaat aaaaccagcg agaaggatca gctcggcagg gaacagatag
     5401 attttggggc cataggcgtt aatatagggt tgatcaacac gtacaaagaa atcatcaaaa
     5461 cccccgccat catggataag gtcgttcaac gttatcccga tctcaactta accgcagaac
     5521 agctcatcgc aatgaccaac gtagcaggat tacatgacac tcaggttatg accatcgttg
     5581 ccactcacta ttcctatgaa aaagcagtaa acattgtcaa tgccgtctcg gaggttttcc
     5641 aatccgaaat tcctaagatc atgaaggtcg ataacattac gattttaaat agagccaaaa
     5701 tgcaggacta tcctgtacct gtgaataaaa aatccaatca gtacatcatt ctaagcttcg
     5761 cagcttcctt ggttgttgct atcgggattg tattactgct ggatgcaatg gatgacacct
     5821 tgaaaacaga agaagatgtg cgccaaatgt ttgccgtctc gacgttagcg tgtgtaccca
     5881 ggatgaaggg caaggatcta aagtcaagta aaggaaggaa gtctagaaag aaagtaggag
     5941 aggtacacca tgtcaatacc atccactaaa tcggaaatta tgatggagac taaccccggt
     6001 tcactagctt cagaatcata ccggtctttg agattcaata tggagacctt tgcactagac
     6061 caaggcattc agacggtttc attgacttcg gcaggtcggg gagaaggcaa gacgacaacg
     6121 gcgctcaacg tagcaacggc ttatgcgcag atcgaaaaga gggttttgct gatcgatgcc
     6181 gacttacgta atccttcgct tcattacaca tttggtggcg ataatagtaa gggactaagc
     6241 agctacctta tgcatcaaag cactctggat gaaattattg cgcctactaa cattcaaaat
     6301 ttatctgtca tcccggcagg cgctgttcca acaaatccgg cggagcttct ggcatctaaa
     6361 gcaatgaagc agcttctgga agaggtaaag cctaggtacg atatgatttt tatcgatagt
     6421 tcctccgtac tgtcattaac tgatggcaaa attgttgcag ctcaatgcga cggagtcctt
     6481 ctagtcgtgg atcatgggaa attaaagcga caagcggcaa aaaaggtgaa ggaagagctg
     6541 gagctggcga aggcgaagct gcttggtgtc gttttcaata aagtcaatcc taaaaatgca
     6601 gagttatttc tatattaatc gttaatggtg tgatagatca gtatcaaagg aaatgttgcg
     6661 aggagagagg gtaagaacgc tcatgagaag aaaacgggtt gggctgcacc gccgaagagt
     6721 aagaaccatc tgcatattgg cgttaagctt tgtcattatt gcaggatgtt cggaaaccat
     6781 accaataagt tccgatggaa atgctgctgc tcaggcgcag gcgctgaaaa gtgttaaggt
     6841 cagcaaagtt accaagcaaa aaataggaga tcccttagtt catgccgccg atgtgcagtc
     6901 ctccgttcaa ttcgatattg tggctaaagc agcgggagat atcgaggcta tcctgaaagc
     6961 gcgtggggat gtagtccaag aaggtgacgt tattgccagg ctgaactcaa gtgaagccaa
     7021 gttcgagaag gagaaggccg cacttgcagt tcagacggtg caggacgcaa ttgtaaaagc
     7081 gaaggaaaga gcgaaaaaag agatggataa tcagaagcgg gacctgaatg actccatcaa
     7141 gaagcaggaa caagcactaa atgatttgac ccgcaactat aataaaacga aaaatgacta
     7201 tgaagtcgga ttggcgacaa aggttcaggt atatcagatg gaggttcaat taaggaacag
     7261 ccgcacggat ctggagctgc ttaaagataa gctggcccga ctagagccgg tagacacgac
     7321 gtcggagctg cagacacaac tgaaaaccac tcaaatggca cagcttcagg tcgagcagtc
     7381 gttgacttat ttggaagtaa aagcacccgt gagcggagta ttgacggagc ttccgtttga
     7441 agtcggcatg agtataccgg caggcaccaa gatcggtctg attcagaagc tggatccgat
     7501 caagcttaaa gcgcagctat ccgaggaaga gtctaagttt gccacgggta aatcggaaat
     7561 gacgtattac atgcaaggag cggcgcaaaa gtctaaagcc agaatcagct tcctctccaa
     7621 agtgattaat cctgatacca aagcctatga gattaacctg gatgtaccca ataaagacat
     7681 gactttaaag ccggggatga aagtatggct tcaattaacc gaagatcaag atcaaatcgt
     7741 gttaacggtt cctacgtaca gtgttgtgaa agaaggacag gattcttttg tctttgtcct
     7801 caccggagat accgttgaaa aacgtttggt acagcttgga cggttaaatg attctactca
     7861 ggagattctt tcaggtgtta aagaaggaga gcaggtcgtc gtttccaatc caggtcaatt
     7921 aaaagataaa gagcaggtac aacgtactgc tgtagaatag taaaaatata attggagtga
     7981 accgtattga gaatgaaatg gaaaccaacg ttgctaatga cccttttaat attctctttg
     8041 ctcattccct ccgcttcttt cttggctatc gcggaagaag gagtacctgt aacgaaagaa
     8101 tattcattga cttcaacggt taaagcagcg gtgaaaagta ttctgaatga gcaggtggcg
     8161 gaaggaacaa gaataggcgc agtcgttcga ttaaccaatg aaggaactcg attaactaga
     8221 gtaccggact atgaagtaag ggttaaagca gaagatggag tactgtatac tctgcgtccg
     8281 agcgccgaga atgttattgc cattcagccg aaggaaactg tggagcttag ctatatgatc
     8341 gtcattgatc gtgaagatac gttctcatta tctgagatat cttgggtcga tgtagatgaa
     8401 ttcgtgtccc cgagatccga gaaaatgatc gtgtccatcc ctatctcttc tattgaatgg
     8461 aggggtgata tcgctgtctt ctccgatgcg cttgccacgc attcgtgggg tgagaatatg
     8521 actatccagg ttttatctac ttcattagaa tataaaccgg ttagcttaag tgagcaaaat
     8581 acgcctcaag ggcctaaaac gattgttggg ctgcttgcca cgaacaaaag tgacaagaag
     8641 aaagccatcc cggattttcg tgtgaacgga agatcggata agaaagtata tacgggtgta
     8701 agactggaga aggatccgat tgtgcttgga cccggagagc agcagtatat ccactatgct
     8761 attcctgccg gaaaaaagga agagttaatt ggattaaccg ttcttacccc tgaaagcttt
     8821 gcaacggatg ataaaaccaa gatcgaatac ttgatcggcc agttcaatgt agctctccca
     8881 caggatggcg gtgtcgttag cgaggcggat caacccaaaa tgtacgtctg gaacagcccg
     8941 attcagtttg atccgttgaa caacgtcgtt caaccagagg ttagtgtctc tatggttact
     9001 cttcaaatgc atgaaagtgt gggaggcgga tttaaagcgg ctgtcgccaa attcaagctg
     9061 accaatcgga gtgaccggcc tatgcctgtc cctaaatttc aagcacaatt gatgggtgtt
     9121 ggcggtacca aatatacggg gactcgacaa actgccgtag tagaaacgct tattcctaat
     9181 gtcagctatg tgatgtacta ttcctttgtc cttcctagca atgagaaggg cgagcagttg
     9241 actatggaca tattggatag tgaaagtgtt gccccgtata acattcctat tgccacgttt
     9301 aaaacgatgg ttaaaaagga aaagtcagag gatacaggtc tgtcctttta tcctttcaat
     9361 gtcaagatta acagttggaa aagtgaagta ttctacggct ctgcaagaga aagcttccct
     9421 tattcctata agctgagcat cgacatggat gtcagcctcc aagaagaggt cgtcgtcgat
     9481 caaaacttcc ctaaactgaa ggtggagcta gttgatgaca aaggaaaagt cataggatcc
     9541 aagacgcttc ctttcattgg ggaaaaccgg gttgctacgg gaacgcaaac cgttaatatg
     9601 gactctgttc tatatgaatt ttctaattct cttcgtgttt acgagacgat tgacacgcct
     9661 tatggtcagg cagaccgact gattgcgaca cttcaataaa cttatctaca tgcatcccta
     9721 ggggaggatt gctttcttat acgcagttgc tccctcggga ataatatatc aatgtaaatc
     9781 caaaccaaag ccaaaaatat tatttacaat aactggttga caccaaagca gtaagatgct
     9841 atcctaaaaa tgttcttaat aaagaacgaa tcaagatcgt tatagataac aaatcggaga
     9901 ataaaaaggt tgaattcaac ggttttgtta ctttttttaa aatgataatt cgttattaag
     9961 aacaacatcc tgcctatctt acagtgttgc ggaggggaac atgagcgcca taactggaat
    10021 atatcatttc actcaagaac cgatacctac ggagcacgga ctaacgctga tgtccggtct
    10081 acagcaattc ccttcggact ccattcatac ttggagaaat gaacatgtat tcttaggctg
    10141 ccatgctcaa tacattacac ccgaatcggc acatgaactc ttgccctatt atgatactga
    10201 aagacagctg gtaataacag ctgatgctat catcgataat cgagaatcct tatttcagct
    10261 gctgcagatt gattatggca gaagaagtac aataacggat agtgaattga ttttgctggc
    10321 atatgataaa tgggaagaaa atgccccgca gtatttagta ggcgattttg ctttcatgat
    10381 ttgggatttg cgcaatggac gattattcgg agcgagagat ttttccggca gccgaacttt
    10441 atactactac cacgatcatc agcgattcgc cttctgtact acaatccagc ccctcttgtc
    10501 cttgccttac acgaagacaa cacttaacga gcaatggctt gccgaatacc tggctatcat
    10561 tggaatggtc gacgtagtgg atgcctcaac caccgtgtat cgagatattg ctcaattgcc
    10621 gccttctcac agcattacta ttgcaggaag taaggtgacg ctgaagcgat attgcacatt
    10681 aacttcgaga gaacggttga agctgaaatc taacgaagaa tacattgaag cttttcagga
    10741 agtttaccag gaagccgtca catcgcggct gcgtacgaac cgtcaggtcg gtgcgcaatt
    10801 aagcggggga ttggattcgg gctccatagt cagctttgct gttaaagaac tgagcaagag
    10861 tgggaaaaca cttcatacat tcagctatgt ccctccaagt gatttcgaag attttactcc
    10921 tgctcatata ttgacggacg aaagaccgtt tatacaatcg attgtaaagc atgtcggagg
    10981 aatgaaggat agctacgagg attttgctgg aagagatcct tatacggaaa tggatagttt
    11041 cctgagcacg atggagatgc cgtataaatt ttttgaaaac tccttttggt taaaggggat
    11101 gttcgaaaaa gcacaagaag cgaatgtagg tgtgctgtta aacggcggaa gaggcaattt
    11161 gagcatttcc tggggttcgg ccatcgacta ttacgctact ttgttaaaac gtctccaatg
    11221 ggtacggttg gctcaagaac tgcactctta cagcaaaaat gtgggcggcg cccgtttacg
    11281 caggctgccc gatgtggctc gaaccgcctt tccaatcatg gatcgcttat ttccaacatc
    11341 ggagcccttt gcctatccta tgctaattaa tcctgacttt gctaaaaaaa cagatgtgtt
    11401 taataagctg aagcaacatg gcatggacca atccgggtgg ttttcctctc ccaatctgtt
    11461 tgaacaaaga aaaagccatt ttgaggaact atttcattgg aatgcaagca atacgctagc
    11521 caccaagctg tccttgaact atgggatatg gaagcgggac cccactaacg atctccgagt
    11581 gatacgcttc tgtctatctt tgccggagga gcagtacgta caaaatggat tggatcgcgc
    11641 actcatccgc agggcgacca aaaccttatt accggacaat gtaaggttga accaatccat
    11701 acgaggtgtt cagggagccg attgggttca ccgcatgatt ccacatcaat ctgcattact
    11761 cgtggaactg gatgaaatga gtgcagatcc aaccatattt gagctcttga acggccctgt
    11821 cataaggcga gctatagaca aggttcgggc gggactcagg cctgaggatg ctactaatgc
    11881 cgaacttaag tttttaatga gaggcatagt tgtctatcga tttcttaaaa aatggacttg
    11941 aaaggaggtg agtaatatga aaaaagcatg gcaaaagcct gtacttgaag tgcttgatgt
    12001 aaatcaaact atggcatcga cagtttacgg tgatttcact gacgaagctt atgtacctgg
    12061 taaaccggtt gatcctaaca acccaagcac ctggaaacgt ttcaacagct aatatgaaac
    12121 aaagtgagct tatacaaccc ttaggttaat gtttgcttta aatgggtatt gtcggtatta
    12181 catatgttaa aagcctttat acaaaccaac gtataaaggc ttttaatgca aaaacggtag
    12241 gtaatggagt ggaagttatg ctacagacgg aaaataagat cgtgtactcg gcctttggcc
    12301 ttcgaatttc aagcgagatt cctttgccgg aattaccgca tatcagcgag ccctcagatg
    12361 aactggatat tgaaattcga aatggagaca taggcaggtt tgccgatcaa ttatttgcga
    12421 ccccctttat gcatgtagtt gatgagggtg cagttatgtt ctatgttccc gataccgcgt
    12481 attattccat acgggatggg cggttcataa cggtctcgcc ggttcaagga gcagacgagg
    12541 atttaatccg tctttacgtt cttggcacct gcatgggtgc attgctaatg caaagaggaa
    12601 tcctaccgct gcatggcagc gcagtagcca ttcaaggcaa agtctatgct ttcgtaggag
    12661 actcaggagc aggaaagtct accttagcgt ctgccttcct tagtcaaggt tattcgcttg
    12721 taagcgatga tttgattgcg gttacccttt ctaaagaaga tcagaagcct atggtgaccc
    12781 cttcgtatcc ccagcaaaag ctatggcaag atagcttgaa tcatctcggt atgtcatcaa
    12841 gcgatttgcg atccatctat ggaagagagg ataagtactg tatccccgtt gcttcgaact
    12901 atgtaacgtc tcctttgccc cttgcaggtg tcattgaact ggtcaaaaca gagaatcaac
    12961 tgcaggttgt aaggatagag aagctggatc gtctacagac attattttat catacgttcc
    13021 gtccattcct aattccacgc ttgggactga tggagtggca cttccagtct agctccgtta
    13081 ttgcgaatca aatctccatg tatcaactaa gcagaccgga aagccaattc acagctcccc
    13141 aattagttaa cctaatatta gatacattat cgatggaggc ataacatatg atccaaaatc
    13201 ataaaatcgg catgcaggat tgcttttccc aagtgacagg aaatattgtt agcgacatgg
    13261 gaggggaaaa ggtcatgctg agcatagcca acagcaaata ttataattta ggcgaggtcg
    13321 gcggtgaaat ctggaattgt cttactgaag cctctagtgt ttcggcagaa caaattgttg
    13381 ccgtcctaat gtcacagtat gatgtagagc aagttgagtg cgagcagcag gtggtgtcct
    13441 ttttggagca tttgttggag gaaggtttaa ttaagtgggc atcgtaagta aggtaaagaa
    13501 gttccttcag ctagatatgg caacgatgct gctaattgca gaagccatct tttatttagg
    13561 atgggcgcgg atgcttgtgt ccattccttt tgccaaggtt gcgccttctt taggtgctca
    13621 tatgcaggaa acctctaatt ccgaaagacg cgatgatata gagtcgctaa ttaaggttca
    13681 cgatattatt cgggtgatga gtcagcatac attctgggaa agcaaatgtc tggttagagc
    13741 cattgcggca ctaaaaatgc tggagagacg tcacatagaa agcacactct acctaggaac
    13801 ggcaagagac gagcagcgca agatgattgc acatgcctgg cttcgcagcg gtccattcta
    13861 tattacaggt gcagaagaga tggaacggtt tcaggtggta ggcacgttcg ccaaacggat
    13921 aagcgataaa ggaaattgaa ggtgaataga atggaagctg gttatcatat ggatgtgtcg
    13981 ttattcccta atgagctgga acttatgctt tccttaatca agacggagga agtgaatatc
    14041 ggcgatacaa gctataacaa ggggcttact gatatcgatt gggccttttt ccttgagctt
    14101 gcaacccatc atcgggtttt ccccacatta tacacaaagc taaaaagcat gaatgaacca
    14161 gggattcccc cgtatgtcat gcaatcattg cgaaatgatt atcaacagaa tacatttcaa
    14221 atgctgcatt taagcgccga gatggacacc atatgcaagc tgctctccga ttcggggatt
    14281 cgctcccttg ttttaaaagg accggtgctc gctgctgatc tttatggcga tatatctcaa
    14341 cgaacatccg gagacttgga tattctcatt cctatcgaag agctggagca tgcggagcag
    14401 ctgcttgtaa gacaaggata tgagaaggat gaatacattc aaacggtatt aaacgattgg
    14461 aagtggagac atcatcatat tacgttcttc catcatcata aagggatcaa ggtagagatt
    14521 cattggagat taggccccgg ccccggcaaa gagcccagct ttcaggcatt gtgggaaaga
    14581 agaaggacca gtgcaataac ccgtcatcct gtctattatt tagggagaga ggatttattt
    14641 ttatttcttg tttcccacgg tgcacgacat ggatggtccc ggcttcgttg gttgttggac
    14701 attgatcgta tggttaagca aagcatggat gtacggaagc ttcgacgatt gcttaagcaa
    14761 tatgagcacc tgcatatagg agcgcaagcc ttgatactcg catcgcagct tcttcatact
    14821 cctttaacag aggagatgag gaccttagcg cagggacagc gtgcaagaaa tctagcccaa
    14881 gaagcattgt tctatatccg gcagatgatt aaccttcata ccgatccaat accgtatgag
    14941 gtatcagagt atcataaaaa gcatctgttt tcattgatgt cgaatcatcg taagctgcta
    15001 tttattttga atttctttta tccgtaccca gaggatgcta acacactggc gctgcctaaa
    15061 tatcttcact tcctttattt tcctctacgt cccttcttat gggtctggag aaaaacgaaa
    15121 aaggttgcct tatcttgagg aggaacggaa tggagcatgt cctgtattac acccgaaaat
    15181 tacatgccta cgcaggtaaa gtgttgtata tgaatcttct aggcatgaca ctgattggct
    15241 tgctggatgg aataggcatt tttttattaa ttcctttgtt aagcgtcagc ggccttctga
    15301 gcattcaaac atcagccatt cctttcatgg gaatgctgga tttcctgaag gatgtgtcaa
    15361 gaccggtcgg tctgctcctg atcctcggat tgtacttttt attagtggtc ggtcaggctg
    15421 cgatccagcg taaccttagc ctaagggatg tccaaattca tgccggtttt gtcaatcatg
    15481 tgagaatgga aacctatcag gcgctattac aagcgaattg gagctttttt attaaaaaaa
    15541 gaaagtcaga tctaatcaac tcgatgacga acgagctggc acgagtgacg aatgggacct
    15601 atgtcttttt gcagcttctg gcatcgctgg tatttatggt gatccagatt ggtatcgctt
    15661 tgtggttatc ggcaaagatg acgctgtttg ttttggcgtg tggcctgata atggccttat
    15721 tctcccgcac attcataaga aagttccgaa tgctgggaac ccaaacctca gatgtagcaa
    15781 gaagctatat tggaggtatt accgatcact tcaacggtat taaagatatt aagagcaata
    15841 tgctggaacc ttcacgttac cgttggctcc agaactggag tgttactgta gctcaagaga
    15901 gatacgagca agccaagcta ggctcgcaat cacagtttta ttacaaggct gcctcaactc
    15961 tgatcatcgc cgtgttcata tacttctccg tcacgttgtt ccaaactcaa ggtgagcagc
    16021 tgctcctgat cattatgata ttctccaggc tttggcccag atttactgga atacaatcca
    16081 atttagaaca aatcgccgct gcgatccccg cctttacatc tttaaccgag ctgcaaaagg
    16141 aatgcatgga aacaagggaa gtcagtatcg gcactctcga ctacaatcaa gtgaagccgc
    16201 tacgtataca agaaggcatt gaatgcaagg acatttattt tagatatgac aaaaattcac
    16261 ccatctatgc tcttgaacat attcagttaa gcattggctc gaatcaaatg acagctatca
    16321 taggccggtc gggagcaggt aaaagtacat tgatcgatat tatcatggga ctgctgcagc
    16381 cggaccatgg ccaggttcta atcgatggag ttccgttgac caaggataac ttgttacgtt
    16441 taagaaaagc gatcagctat gtccctcagg acccgttttt gtttaatgga accattaggg
    16501 aaaatctgct cctcatgaat cccaactcca ctgaagaaga gctgtgggaa gccattcaat
    16561 ttgccgcagg ggaatttgtg agtcgactgc cccaaggctt ggatacgctt ataggtgaca
    16621 gaggagtcag gctgtcaggc ggagaacgcc agcgtttagt tttggcaaga gccatcttaa
    16681 ggaagccatc gattcttgta ctggatgaag caacaagctc tttggacaca gagaacgagg
    16741 ctaaaattca agaggcattg gaaagactaa agggaaccat gacgatcatc gtgatagcgc
    16801 accgcttgtc gaccattcgt aacgcggacc aagtcattgt attagatgaa ggagctatcg
    16861 ttcaaagagg cggctttaat caattggcaa aagaaagagg caaagtgttc gctcatttgt
    16921 taggcagtca gttccaggat tcgacaatga tttcacaaaa gtaaaatttt gtattgacat
    16981 gttcgttata aagaattacc atgaagtaag aagcaataat agtgctgttc ggggtgaaaa
    17041 tggtggtgac accttcattt ttttgtccag tcgttcttta tagagaatta atcatctgaa
    17101 tataaggagg aacacgaagt gatcgcgaat caccatccaa cccgtcaaat accaagagtc
    17161 attcattatt gctggttcgg cggcaaagag aagcccgata tcgtgaagcg atgtattcaa
    17221 agctggcagc agcatctaca gggctatgaa atatttgaat ggaacgaaga aagctttgat
    17281 ataaacacga atttatacac taaacaggct tatgaagctg ggaaatttgc atttgtcagc
    17341 gattatgtaa gagttcacgc tttataccat tttggcggta tctatatgga tacggacgtt
    17401 gaagtattca agtcttttga cgatctgctg catcatgcat cgttttgggg atttgaacag
    17461 gagaattaca tagcgacaag tacgataggt gcagcaaagg ggaataagct tattcaacgc
    17521 ttcctggaat cctatgatgg taagagcttc attaaagcag atggcacgca tgatgattta
    17581 accaatgttg ctatcgtaac gaagatgctg gaggagcttg gtctgaaacc ggatggacag
    17641 taccaggaga tggaaggaat aggcgtcttt tatccacaaa cgtatttttc tccttatgac
    17701 tatattaact gcaggaagtt tattacagaa aatacatatg ccatgcatca ctatcataaa
    17761 agctggctgt ccccaaaagc aaggcttaaa agcaaggtga aaacgatagc ggcccaatgg
    17821 attggcgggg acaatattgc gagactgaga aaattggtat ccaaaatgta gggggtcatg
    17881 atgaagaaca tattggttgc ctcctatgac atggaagttg gaggagtaga gcggagtctt
    17941 gccagtatgc tggagcactt cgattatgaa caatattcgg ttgatctgat gctccataga
    18001 cataagggcg attttatgaa cctactgtct cctaaggtgc gcttgatcga tgaaattccg
    18061 gagtatgcga cgtttcgcaa gtccattgcg gagacgatca aagacaggca ttacaggatc
    18121 gggatatcaa gggttgcatc cagagtgagt gcaggactcc tcgggaaaat tcgcaatatg
    18181 gcggaaccgg gatactatca aatgcagctg atgtggaagt acgcgctgcc ttatttgccg
    18241 agcctggaaa aaccatatga tgtcgcgatc agttatttgt ggccgcatta ttttgtcgca
    18301 gagaaaattc atgcccgaca aaaaatagct tggattcata cggattattc caatattgat
    18361 accgacatat cgctggatct tcggatgtgg aatcaatttg acctcattgt agctgtgtcg
    18421 gatgcttgcc aagcttcatt tcttgggaaa tatccttcgc tagagccaaa agtcatcgtt
    18481 atggagaaca tcacatcacc ggaatttata agaacaatgg ccaacaagga agctgctgaa
    18541 cctatagaga gtgacagccg tttcaccctg attacggtcg cccgattgtc tcatgccaaa
    18601 gggatcgaca atgcagtaag agccctgaag ctcctgaagg ataaaggcta tgacgatatc
    18661 gcgtggtatg tagtcgggta tggtggagat gaggctatga tacatcaatt aatagcagag
    18721 cataagctgg aggaccgctt tattttatta ggcaaaaaaa caaatcctta tccgtacatg
    18781 aaggcagcca atctctatgt acagccatca cgctatgaag gtaaagccgt tacggtcacc
    18841 gaggctaaga tcttaggtaa gccggttctg attaccaact atcctaccgc aggcagtcag
    18901 gtagataacg aagtcgatgg agtgatctgt gatttgaatg ttgagggaat agccgagggc
    18961 atcgagagaa tgtataagaa gcaggagctg agggtgcagc tgatggacaa tattaaggat
    19021 aaggattacg gaaactcctg tgaattagaa aagctatacc ggctcattgg ataaggcctt
    19081 tagactatag agagatttta gttgcggagt gattagagac atgagtatca aagtaagcgt
    19141 gattgtaccg gtgtataacg cagagcagta catagcccat tgtattgaat ccttgttaaa
    19201 ccagacgctt gaggaatgtg agtttatctt tgtaaatgac ggctcgaagg atcaaagcgg
    19261 gcaggtcatt gaggagtata gcaaaacgga ttcaagaatt aagctggtcc atcaatcgaa
    19321 ccaaggagta agcgcagcca gaaatgcagg attacaggaa gccacaggaa cctatatcgg
    19381 tttcgtggat gccgatgatt atgtagacaa ggacatgtat gaagtactct acaacacagc
    19441 aatcgagagc gattacgacg tggttatttc caattttgaa agtgagattg agggtcataa
    19501 ggtgataacc acttatccgt tcccactcgg gacggttctg aagaaagatt atatcgagca
    19561 agaagtttta acttatttcc tcaaatcaga tcaattgaat accgtctgca gtaaattgta
    19621 taaaaacaaa cggatacaag attataaagt caagtttccc gagaaagtag cattagggga
    19681 agacggattg tttaatatgc aattttttag acatgcggat cgcattcaat atatagacta
    19741 taccgggtac cattatcgcg aagtcgttgg aagcgcaaca agaaatattt tagaaaaaga
    19801 ctactttaag cgggctttag aagtgtacac attagacatc ccagagatgt acttaaccac
    19861 attggataag atgaggatcc agcagctgcg atccatcaag cttattaaca gtgtcatgtc
    19921 ctatatttac gtatacttca aatcatcgaa tgagatcagc tttcgccaaa gaatgaagta
    19981 cgtcaataac atgattaatg atccgtgtgt gagggaagcg ttgccctact tctacagcga
    20041 aatgtatacc tccttgggga catatgagaa atttcttgcc gatatgattc gaaaaagatt
    20101 cacgctgggt ctgtttgttg ccaccactta cagcaggtta agaaataaag cttagctgta
    20161 aggagcgctg cataattcaa aggaggagct taagaaatga agattatgat gtttgcccac
    20221 gatgggagtc tgaacagggg atgcgaggcc attgtacgct catcgaccca tatcattaag
    20281 gaaaagattc aaggcgccaa ggtttacttg gcatcaggga agcctgacac ggacaaggtg
    20341 atctcgaagc tggacggcat ttatgacggt tctgcccgcg gaatcaagaa gttttcctat
    20401 gattggtttc tttcggcagt caaggtaaag ctgttccagg atgagaccta tgcactcggt
    20461 aaaattcata acaatattgt gaagcatatt cctaacatgg acgtctgttt atcgattggg
    20521 ggggacaact attgctacgg ggagcagccg ggctggtatg aaattaaccg cagggtgaag
    20581 gcctcgggca agaaactcgt attatggggc tgctctatag gggaagaaga tatgtccgat
    20641 agaaagctgc aagatcttcg cttgttcgat ctgatcctcg cccgtgaaac gttgacctac
    20701 gatatgctgg ttgcaaaggg gctaacgaac gtcaagctgt gtgcggattc tgcgtttacg
    20761 atggagaagg aagagctgga actgccggca ggctggcaag aaggcaatac ggtagggctt
    20821 aatttcagtc cattagtatg gaagaaaaat aaagagtcca gaacagccgt gaaggacctt
    20881 atccaacaca tccttgatac gacagatatg gccatcgccc taacccccca tgttatggaa
    20941 ggcggtaaca atgattatga ggttcttcag caatactatg aggagttcaa gcacacccat
    21001 cgggtcatcc tgctgcctaa tcatttaact gctatccaat ataaaggcta catatccaga
    21061 atgagatttt ttatcggagc tagaacgcat gcgaccatag cggcatattc caattacgtt
    21121 ccaacgatgg tgcttggcta tagcgttaag tctaagggca tatcgaagga tatttttggt
    21181 gaagaaaaat tggtattaag tattgatcaa atatcgaaca gcttcatgtt gaaggcgaaa
    21241 tttgatgaga tgatcaaaga agaagggctg attaagcaaa agcttcaggc atcgatcccc
    21301 cgcattaaaa agatgtccta caaggctgtt gagtatttag ataagctagt tcaataaaaa
    21361 gagggttata ggatgaagaa gaacttactt tttgttatgc caagcctgac agccggtggc
    21421 ggagagaaaa gtttagtgaa tttgttatca caaattgact ataaagccta taatgtggac
    21481 ttatttctat tcagccaaac cggggtattc attaattccc tgccgaaaga agtcaatata
    21541 ttgggctttc ccaacaaata caatatttac actaaaggct tgaagaagtc gatggaggag
    21601 tttctagcca aaggtcaggt gaccttagct tactccagac ttatgttcac ggtgatgaac
    21661 cgagtcatca gaaatacaga cttttcagag caattcacat ggaaatatca aagaaaatca
    21721 ttggatacat tggaaaaagt atatgatgca gccattggat ttcttgagaa atcatccatt
    21781 tactttgtag tggataaagt gaaggcccgg aagaagatcg gatggattca tacgaattac
    21841 tccgattcag ggatgagaca tcactatgac gatccgtatt tcaagcagct ggatcatatc
    21901 gtaacggtat cggaagagtg tgccaaatca ctgagcgatc attttcttca tttgaataat
    21961 aaaattaaag tgatctacaa catcgtatcg ccgaagatga tccatcattt atccaatgag
    22021 gacatcgatg aaggtaccat atttgatacg gaatatacga acatcgttac actagctaga
    22081 ttaagccacg agaagggcat cgatctggca atcgaatcct gcaaattact ggtgggcaag
    22141 ggccacaaca taagatggta tgttctaggg gacggacagg acagggaaag cttggaatct
    22201 cttatcgaga agcatcaatt aggcccctat ttcaagcttc ttggagttaa ggaaaatcca
    22261 tatccgtata tcaaaaaggc agatatttac gtccagcctt cccgttacga aggtaaatcg
    22321 atagcgatcg acgaagccaa aattcttcaa aaacccattg tcgttacgaa ctttgaaact
    22381 gccaaggatc aaattcaaca tgggatcaat ggtgtcattg tagatttatc tcctgcgggg
    22441 atctctcaag ggattgagaa gctgatggaa gatatcccat tgaagaatag ggttatttgt
    22501 aatctagcta ttgagaagct gggcacggag ggagaaatac ggaagctcta cgaaatttta
    22561 tgatgcgggt ggttgttgct tgtgaagaag agagttttgt ttgtcatgaa caatatgcgc
    22621 tgcggcggag ccgagaaggc attgatttcg ctgctggaaa cgatggatta ttcagcatac
    22681 gaagttgatt tattcttatt caagcatgac gggatattta tgaaccaaat acccgagtca
    22741 gtccatttat tggaagagcc ggcagaatac cagtattatg atatgtccat caaaagagcg
    22801 attcttgatt gtgtgagaaa aggaaaatta catattgctt tattcagagg ccttgcaggc
    22861 gtgattttta aaagtgaaaa aaacagagtt cgatgtgaac agagggtttg gaagtatata
    22921 tcgaagtcgt tgaaaaacat agataagcct tatgatattg ccgtagggta ccttgaaaaa
    22981 aatccgatat atttttgcat agacaaagta aaggctcata agaagatagg atttattcat
    23041 aatgactatg acaaattggg catggacccg gagctggatc gctcttactt tgacaagctc
    23101 gaccatttgg taacggtatc tgaagaatgc ggccatgttc tcaagaatag atttcctatg
    23161 tatcagcaaa aggtggacgt catgtataac attgtctctc ccgccgcgat atccaaatta
    23221 tcgcaggagc agtccgaatg ggatgatcgt cgcatgaagc tggtttccgt aggacggctc
    23281 aatcatcaaa agggcttcga gctggctgta gagacttgta aagagctggt gcataacgga
    23341 tatcccgtca catggtatgt cattggtgag ggagaggagc ggggaatgct ggagaagctg
    23401 atagcagcta acaacctcca agatcgcttt gtgctcatgg gattaaaaga aaatccgtat
    23461 ccgtacataa aagaagcaga tatttatgtg cagccgtccc ggtttgaagg aaaatcgatt
    23521 gcaatagatg aagccaaaat tcttcacaag cccatcgtcg taacgaactt cagcacggct
    23581 aaggatcaaa ttaacgacag ggagaacggc ttgattgtag agatgaactc tacatcgctg
    23641 tttcatgcta taaaatcatt gatcgatgac gaggagctaa gacgtaaatt gacgctcaac
    23701 ttatcgaggg agaagctggg gaccgaatct gaaattcata aattatatga actattcgcg
    23761 taataggaaa ggaacgattc catggtggtt caaatcttaa gtgtggtgtt actgagtctc
    23821 attgctgtaa tcatccttat cgatgtcatc cctatgttca aggattgggt cagcagaatc
    23881 catattggac gctaccaaga taaacaaatg tggaataaat ccattacgac aagagggat
//
