LOCUS       NZ_JMLS01000017        23543 bp    DNA     linear   CON 10-FEB-2024
DEFINITION  Paenibacillus sp. UNC451MF BP97DRAFT_scaffold00014.14_C, whole
            genome shotgun sequence.
ACCESSION   NZ_JMLS01000017
VERSION     NZ_JMLS01000017.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Paenibacillus sp. UNC451MF
  ORGANISM  Paenibacillus sp. UNC451MF
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 196170)
  AUTHORS   Dangl,J., Huntemann,M., Han,J., Chen,A., Kyrpides,N., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-2014) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Paenibacillus sp. UNC451MF
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi0054671
            Gene Calling Method               :: Prodigal 2.5
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2014-04-01
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/10/2024 01:27:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,772
            CDSs (total)                      :: 6,708
            Genes (coding)                    :: 6,634
            CDSs (with protein)               :: 6,634
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 3 (5S, 16S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 18 of 74
            Pseudo Genes (incomplete)         :: 59 of 74
            Pseudo Genes (internal stop)      :: 15 of 74
            Pseudo Genes (multiple problems)  :: 15 of 74
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:46:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 120637
            Orig. end                         :: 144180
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JMLS01000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..23543
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23543
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23543
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13543](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13543
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            780..1727
                     /locus_tag="BP97_RS0117640"
     CDS             780..1727
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019914156.1"
                     /locus_tag="BP97_RS0117640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YafY family protein"
                     /protein_id="WP_028550273.1"
                     /transl_table=11
                     /translation="MSKSKRLLELMMTVNRKRKFTVKELAMEFGVSTRTMLRDLQELSE
                     LGVPLYSEVGPHGGYQVLKERILPPIAFSEEEAAALFFAVYALRHYSSLPFEAESASAL
                     DKFYLHMSGDVRDRIDEMKNRVDFVTPTRQQESPYLSILLEAAVQQKVLLIQYEPRGEE
                     AGRKIQPIGIYANNGLWFCPAYCFLRKDFRIFRCDRIQSAAYDVDGTEPMDLRHVHLEN
                     KELVFQKEKESTQLYAELSRKGVQMCEAVLWLGSHLNIREDGTGWLEGPIPQSDLAFYA
                     RFFIGLGNEATVKHPTELIDYIKRLFKEIMSNYE"
     gene            1827..2135
                     /locus_tag="BP97_RS0117645"
     CDS             1827..2135
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018755909.1"
                     /locus_tag="BP97_RS0117645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028550274.1"
                     /transl_table=11
                     /translation="MSQRYRITRAFQENGNSEQTITLEECKEYFTSKPDFAYTPVFTVT
                     GSTSMSIEGDFFMWSYGEVKIPFRYYEGDIYVSGTNEAVIPKMLEVASDLRADVAEG"
     gene            2371..>2586
                     /locus_tag="BP97_RS41575"
                     /pseudo=""
     CDS             2371..>2586
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019715504.1"
                     /locus_tag="BP97_RS41575"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="YiaA/YiaB family inner membrane protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYPKYQRRNTLAFTAASYFALAAGIFLYCLGIYNADWQLNVKGYY
                     LLCMFLIIITSIVTQKVIRDNAEDKEL"
     gene            2638..2835
                     /locus_tag="BP97_RS41580"
     CDS             2638..2835
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017198.4"
                     /locus_tag="BP97_RS41580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YiaA/YiaB family inner membrane protein"
                     /protein_id="WP_331281311.1"
                     /transl_table=11
                     /translation="MAIVGLIIGFCMFFIGLYNATFELNEKGYYIAVMLLISYSSIGVQ
                     KVTRDNAEDKEIFENHNLNG"
     gene            complement(2894..4258)
                     /locus_tag="BP97_RS0117655"
     CDS             complement(2894..4258)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008180067.1"
                     /locus_tag="BP97_RS0117655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_036746110.1"
                     /transl_table=11
                     /translation="MPDTENSIFGPKYIALSIGIILAVMAVGFEGLAVITVAPAIAGDL
                     NGIHLYGWIFSAYLLAQIIGTLVVGRQIDKKGPALPFTLAMILFALGLIAAAMANHMLI
                     LIISRALQGFGAGAMMTCVYTAISLSYPDKLRTKILGAFGTAYVLPSMIGPYVAGVIAQ
                     QLSWRFVFWGVLPFLLLAALLSLPVFRKLQVPAVQERSTSGSTWLSILLAIGTGIFLSG
                     LGMLPKAIGLMLIVGLVFMIQPLRKLLPSGTLRLRQGLPSLIASRGLFFAAYASTQNFL
                     VLSLTDTKGVTADVAGLVVASAALSWCAISFMQSYWDTADQGRGRHKRIIIGVLFMIVG
                     IGIVFWIPTSTIAVSVIGQMITGIGIGLAHPTSGAVAFANSKEGESGEVSANLQFADSF
                     TPGIVIGIGGALIAITQSTGLDMETSITIAMTLNLVLILTSLFAGSRMKKAVQAG"
     gene            4432..5091
                     /locus_tag="BP97_RS0117660"
     CDS             4432..5091
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009675638.1"
                     /locus_tag="BP97_RS0117660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_028550277.1"
                     /transl_table=11
                     /translation="MKNNSHGREANAEKTRRTIVKLLKQQGPSDALQLSTELGISRMAV
                     RQHLYDLHEQQLVTFEEEARAMGRPAKMWRLTQEANRLFPDGYADLTVNLIDSMREAFG
                     EEGLEKLLEIRNRKQVVEYKKKAPVHLPLNEQLQALAEQRTAEGYMAEIIENADGTYYF
                     VEKHCPICEAAQVCSGLCSKELEMLQLVLGNEVIVERKEHMLTSGSRCVYQIQRCC"
     gene            complement(5205..6203)
                     /locus_tag="BP97_RS0117665"
     CDS             complement(5205..6203)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550938.1"
                     /locus_tag="BP97_RS0117665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_028550278.1"
                     /transl_table=11
                     /translation="MDPDPERENLLSLIKKGNKSSAIAMIGNAFIAIAKGVGASMSGSG
                     AMFASAMHSLADSINQGFVFVGSILAEKKPTRQFPTGFGRVINIFCMIAVIVVSIMAYE
                     TVREGWHLIHHPVQAGQGIWLNIVALLFNLVVDGLILLKAMKEIMKEARVETRGLGFIV
                     ASFKHVGRSAPPTRLVFYEDLVAVTGAALAMMAVLITSLTTFEALDGVVTILIGLLMVG
                     VAFRVGYDNMIGLIGVAAPRDVAEKVAMLILSDKDVIDINEIRITQEGRYYHVDAMIEL
                     RKGLTLADADDIKFRVQDKLIADPDITDVVLGILEDNGVKDWTPDVLNKFA"
     gene            complement(6417..6800)
                     /locus_tag="BP97_RS39740"
     CDS             complement(6417..6800)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007130461.1"
                     /locus_tag="BP97_RS39740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YmaF family protein"
                     /protein_id="WP_197035485.1"
                     /transl_table=11
                     /translation="MEIPITGFIFHSNDSESDHSHKLYITSWDGRPVHSHPFSGITSFD
                     AGHDHHYAGMTEPAASGVQHTHDYYAVTSLDDGHTHNLRGVTGPAIDFPTGGHYHYFQG
                     FTTVNGRFPHSHRYQGTTGREVG"
     gene            7027..7272
                     /locus_tag="BP97_RS0117670"
     CDS             7027..7272
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015846159.1"
                     /locus_tag="BP97_RS0117670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028550279.1"
                     /transl_table=11
                     /translation="MVKNNERNRNDDSAQETTEMAGADVGEAVGTAGGGALGAIVGSAL
                     GPVGTVVGGIVGAAVGNKAGENVGDNEAANDNNQKD"
     gene            7605..7919
                     /locus_tag="BP97_RS39745"
     CDS             7605..7919
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071378.1"
                     /locus_tag="BP97_RS39745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="heterocycloanthracin/sonorensin family
                     bacteriocin"
                     /protein_id="WP_081824247.1"
                     /transl_table=11
                     /translation="MNEFQNDLQQLSVSSQFQSSEMTPWSQQSQYPEGQYPYGVNPVDP
                     ARLCIGFGVGFCVGFCGGFCTGFCGGCGGCGGCGGCGGFRCGGFRCGGFRCGGCHHRCR
                     "
     aSDomain        8076..8372
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BP97_RS0117680_Heterocycloanthracin_C
                     _RRE.1"
                     /evalue="5.30E-53"
                     /identifier="RREFam011.1"
                     /label="BP97_RS0117680"
                     /locus_tag="BP97_RS0117680"
                     /protein_end="99"
                     /protein_start="0"
                     /score="168.0"
                     /tool="antismash"
                     /translation="MTNLTPAARLKVKEDTFFLPVPNDAVYFRNNVGTFRMEGGMIERW
                     IEKLVPMFNGEHTLADLTNGLSHPHRERVYEIANVLNQKGFVRDVSKDRPHQLS"
     gene            8076..10004
                     /locus_tag="BP97_RS0117680"
     CDS             8076..10004
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009676365.1"
                     /locus_tag="BP97_RS0117680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_028550281.1"
                     /sec_met_domain="TIGR03693 (E-value: 6e-219, bitscore:
                     721.6, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     3e-52, bitscore: 168.0, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.4e-15,
                     bitscore: 49.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNLTPAARLKVKEDTFFLPVPNDAVYFRNNVGTFRMEGGMIERW
                     IEKLVPMFNGEHTLADLTNGLSHPHRERVYEIANVLNQKGFVRDVSKDRPHQLSNEIIQ
                     KFAAQIVFLESFGDSGAYRFQSYRQTGVLAVGSGPFFVGLVSALLESGLPKINMLITES
                     EPTNRERLAELADQARLSDPDVVLKEINKRKEGADGWRDAVQPYQAILYVSQVGDLEEF
                     RLLHAVCKAEKKVLLPAMCLHQTGMAGPVVHPEYEGCWESAWRRVHQTAVHKNPEQHSF
                     STTAGSMLANVIVFELFKKVTGETELRNSFFLLNLETLEGGWHPFIPHPLVHGFAKPQA
                     DRASKLQFDGKEESSDPDASNRLFTYLNQLTSPQSGILHIWEEGDLKQLPLSQCRVQAV
                     NPLSEGPVEMLPEMLGTGLTHEEARWEAGLIGIEAYVARLAEMLVPTKEVMGIGVGGTT
                     AEAMLRGLQANLTERLAAQQEVRKPYVTRVQLSRVEDERCRYYMQALTAMGKEPVIGLG
                     EEVLGFPTVWVGTTDYWYASTGLNKTMALQRALKAALQKVQNQSVYPAHHVLETASVRI
                     GNETMSDLMIPSSEGTAQSQTALQEALEILTKNGKQLFVVDLAVEPFLKEGLSGVYGVL
                     LREGESR"
     aSDomain        8097..8342
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BP97_RS0117680_Thiopeptide_F_RRE.1"
                     /evalue="6.00E-16"
                     /identifier="RREFam004.1"
                     /label="BP97_RS0117680"
                     /locus_tag="BP97_RS0117680"
                     /protein_end="89"
                     /protein_start="7"
                     /score="49.2"
                     /tool="antismash"
                     /translation="ARLKVKEDTFFLPVPNDAVYFRNNVGTFRMEGGMIERWIEKLVPM
                     FNGEHTLADLTNGLSHPHRERVYEIANVLNQKGFVRD"
     gene            10001..11944
                     /locus_tag="BP97_RS0117685"
     CDS             10001..11944
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013877478.1"
                     /locus_tag="BP97_RS0117685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_028550282.1"
                     /sec_met_domain="TIGR03882 (E-value: 2.3e-46, bitscore:
                     151.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 4.2e-86, bitscore: 283.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 3.6e-126, bitscore:
                     414.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVGVAIIGEGGLAGLVSKEMSSLCQVVRLNDFKEEVPESVDFAL
                     VLHDAWHPSVHREAEEMFRAAGIPWLRGFVTFGEGVIGPLVRPGVSGCSHCADTRHLMA
                     GRDRKEMWMLEQRLTEAGGIPHDAWASRTGLLQMTHLLVKESQKVIQGKRSQLEELMFF
                     LDLKTLTGKTHFFLPDPLCPTCSYLIEDTPERASILLQPSPKINRKSYRSRSLEDLAGF
                     LVKDYLDYKTGFLNGKMVDLVSPFADVSVNLPMFDQDEPTAGRTHSYAESELTAIMEGL
                     ERYCGMAPRGKMPVIHDSYRNLANHALDPSAVGLYAKEQYEQPHFPFKPFHSEEPIDWV
                     WGYSFERQSPILVPQQLAYYSSPCGHGFIYETSNGCALGGSMEEAIFYGIMEVVERDSF
                     LMTWYAQLPLPRLDVHSTGDSELELMINRLRTVAGFDVYLYNATMENGIPSVWALAKNM
                     KPKGVNLICAAGAHPDPVRAAKSAVHELSGMMLTLDGKFEENRERNVQMFHDPWLVRSM
                     EDHSMLYSLREAEDRLQFLLEDNRPLRTFQEEFKQAPEHTDLTDDLKAALQSFHRLKLD
                     VIVVDQTTPELKRNNLYCVKVLIPGMLPMTFGHHLMRVTGLDRVLKVPALLGYVKQPLL
                     LEQLNPHPHPFP"
     gene            11966..13543
                     /locus_tag="BP97_RS0117690"
     CDS             11966..13543
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003252868.1"
                     /locus_tag="BP97_RS0117690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_028550283.1"
                     /sec_met_domain="PF00881 (E-value: 1.6e-09, bitscore: 31.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLEKFLGSLHSDSDDFKPSDWEVDWDDAPLTYKLYRNLPVIPLS
                     PELPLSLYRYKSPANPDLTTIGHILWHVYGLTRINQLPTYSSMGYTGSPVQMYRRFVPS
                     GGGLYPNELYVYLKTADAPVGVYHYDAAHHRLVLLREGDFDSYLTRALGNRCDISGCFG
                     TVFTSVMFWKNYYKYNNFAYRLQGLDTGVLTGQLLEVTRRFGYESSVYFQFLDRAVNHL
                     LGITDQEESVYAVIPLSAKPTATRLNQGIVELAGSSAVELCRELPVIRHEHYVRSLEIK
                     EYPMLTKMNEASMLDSTSSFGYVKAVKHVESGLQTVFMPRVDRLTYDLASVCRKRASPE
                     SNFVLSKVTQSEVATLLQEATASLSYNNDLNGNNENPISRISLYCCLYNVDGIPNGAYC
                     YDSEAHLLRRVRPGDQRLRLQKGMSLDNVNLFQVPMCLHVVGDKDYHKSVLGYRGYRIQ
                     QMEAGMLVQSLLLAASSIGLGGRPLLGFDPALCDELYQLTDQGKTTLIQIPIGHYRYRA
                     LLEGSLHS"
     gene            13658..14218
                     /locus_tag="BP97_RS0117695"
     CDS             13658..14218
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="BP97_RS0117695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_051620698.1"
                     /transl_table=11
                     /translation="MDTLEYQITDEWDETRWITVEQIYEQAFPLDGKKSRDIIRRMFEK
                     RMCQLHTIAQGSEIVGMALTGIDKQADALLIDYLAVRTDVRGRGYGRLLLDRIKQWTRT
                     AAGCKGIIVEVESEPTEENSRRVHFWEMNGFHLTAYVHQYIWVPEPYQAMYLNFDEMDR
                     LPEDGIMLFRSITRFHEKAYRRK"
     gene            14307..14516
                     /locus_tag="BP97_RS0117700"
     CDS             14307..14516
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP97_RS0117700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028550285.1"
                     /transl_table=11
                     /translation="MTDQQSNQHEQSARTKAQNELNHALHALNEATHSNVNREQDVQAA
                     KEQLQKAQLEHMQAKVSDSQDSLS"
     gene            14654..15052
                     /locus_tag="BP97_RS0117705"
     CDS             14654..15052
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820094.1"
                     /locus_tag="BP97_RS0117705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RrF2 family transcriptional regulator"
                     /protein_id="WP_028550286.1"
                     /transl_table=11
                     /translation="MRFTKATNYALHTMLLLVDASSAKPVGVQQLAESQGVSPTYLSKI
                     LTRLVKAGMIESISGANGGYRLSRKKDDINFLDIIHAIEGNASLFECDFVHGDECLIQA
                     VMKEAEEKMEGHLKNTKLMDLAKKQTQV"
     misc_feature    complement(15157..15172)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            15167..16069
                     /locus_tag="BP97_RS0117710"
     CDS             15167..16069
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422201.1"
                     /locus_tag="BP97_RS0117710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_028550287.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.3e-24, bitscore:
                     78.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIYDCAIIGGGPAGLNAALVLGRARRSVALFDNNRPRNAVTHASH
                     GFITRDGVTPAEFRRVAYEEVLRYPSVDHLQTEVVTVSKIDSGFEMIDSSGVVTRARKL
                     ILATGVKEIFPEIEGLHPLYGKSLFNCPYCDGWELRDQPLVIVSEHSSVFHTAKMLHNW
                     SKDLIVCTNGQVSLSDEQKKRLLSKGIDVIEKPIAAFIGKDGQLEHVRFADGTQIPRAG
                     GFVAPKFVQSAPFGERLGCERTELGGIKTDHSGRTSIPGLYSAGDASYFMPSQLIFAAA
                     DGSRTAMGVNMDLTEEDFE"
     gene            16205..17470
                     /locus_tag="BP97_RS0117715"
     CDS             16205..17470
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020620454.1"
                     /locus_tag="BP97_RS0117715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding protein"
                     /protein_id="WP_028550288.1"
                     /transl_table=11
                     /translation="MEVFRNWAGNYKYSTSHLHVPENTEQVQELVARCGRIKVLGTRHS
                     FNGISDSTENLLSLQKLNRVIALDRTSSRVTIEAGVRYGELCQYLHSNGYALHNLASLP
                     HITVVGACATATHGSGDLNGNLATAVHSLEVIKANGETIVFSRDQQDGVFDGTVVGLGG
                     LGVVTKMTLDILPEFQMSQQVYDNLPLVQLKDHFDDIFSSAYSVSLFTDWKNATFNQVW
                     IKQKTTNQSSDPMEPEFFGAARATARRHPVPGQTSENCTEQMGIPGPWYERMPHFRMDF
                     TPSAGEELQSEYFVSRHDAYQALCAIDQIREYISPLLYVSEVRTIAKDELWMSPCYKQE
                     SVAIHFTWKPNWEAVQKVLPIIEEKLAPFHARPHWSKLFAMQPEQLHSLYEKLPDFQQL
                     LLRCDPEGKFRNDYLNKYIMGN"
     misc_feature    17488..17506
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.84"
                     /tool="antismash"
     gene            17669..18382
                     /gene="aac(2')-IIb"
                     /locus_tag="BP97_RS0117720"
     CDS             17669..18382
                     /codon_start=1
                     /gene="aac_2__-IIb"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678079.1"
                     /locus_tag="BP97_RS0117720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="kasugamycin N-acetyltransferase AAC(2')-IIb"
                     /protein_id="WP_028550289.1"
                     /transl_table=11
                     /translation="MSNQDWIKPYKLVEYHAEALFTHDHNLRLRTINEPWPGAADAPRF
                     FLGRSIEGTTLSRFRYDVQEKLVRQLEGLCADEPIVTDFQTKPKHFEAYMNLLQGKRFT
                     MGPCYLVPREAASTMKVVNVNRENMKELLGGNFEWMTSEIDYAQPCVALIRENQAVSIC
                     RSVRITSMAHEAGLETLEEFRGIGYAASVVAGWAMEVRKVGGLPLYSTSWDNLASQSVA
                     RKSALSFYGVNFTVY"
     gene            18501..19037
                     /locus_tag="BP97_RS0117725"
     CDS             18501..19037
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018393497.1"
                     /locus_tag="BP97_RS0117725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyltransferase"
                     /protein_id="WP_028550290.1"
                     /transl_table=11
                     /translation="MSITIRKELLDDYKLTERIIKNAFANLEFSDKKEHELVARIRKSD
                     VFIPELSLVATDKDNNEIVGHILLSKIKIINDNQSVESLALAPVSVLPNYQNKGIGEQL
                     ILEALQKAKEFGYHSVVVLGHPQYYPKFGFKKASLWGITAPFEVPDEAFMALELRQGTL
                     DNASGVVEYPSVFFD"
     gene            19283..19729
                     /locus_tag="BP97_RS38955"
     CDS             19283..19729
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024515.4"
                     /locus_tag="BP97_RS38955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FixH family protein"
                     /protein_id="WP_051620699.1"
                     /transl_table=11
                     /translation="MINYTKYMRKSILSLVSLAFLFMSTACSGAIDAKSSSAQAVDVDV
                     KTVQEVLLPGRAILIDADVAQGNNKVKDADDVKIEIWKKDSDNHKMITATHWLDGTYRT
                     KTLFSESGTYYMRAHVKDQRGDVTTTEQELFVKDVLPSESQIKS"
     gene            complement(19816..20718)
                     /locus_tag="BP97_RS0117735"
     CDS             complement(19816..20718)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678456.1"
                     /locus_tag="BP97_RS0117735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_231506330.1"
                     /transl_table=11
                     /translation="MSINLHALMLFYHVAIAGSVTEASKRLNISQPAISAQIRNFEKQY
                     GIILFEKKGRNLVLTPFGQKLFKPTEKLFILEEQIQGMIEDYQSHPKGKLRISGNYLAT
                     SVLIPRWASLFKQKYSQVEVEISTVNSQNAFESLNNYEVDIAIFGNSNITTQTNHSLQC
                     LELYSDEFVFVVAPNHKYANQHISIEEMIKEPFIMREEGSTTRKRLVEVCTAQNVSPPS
                     IELQFNGLNETIQAVVAGYGVSYVSLLVASQFIRRGELAKVEVDGIRLTNKIVLCSHEP
                     AYLEGYIRDFISIVLKNKA"
     gene            20823..21479
                     /locus_tag="BP97_RS36755"
     CDS             20823..21479
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678457.1"
                     /locus_tag="BP97_RS36755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_036746111.1"
                     /transl_table=11
                     /translation="MDSTSVYLVRHGQTEWNVEQRMQGHLDSPLTREGQKQAAQLRDRL
                     KEMKWDAIFSSSSPRAVQTAEIISGMNREHVRQLDAFKEINMGLWEGQLLTEIHGLYTR
                     EYGRFFEEPHLYCPTEGGETYFELLVRGVSALEDILTAFKGGKILIVTHRITLKVIMNY
                     YFGNTLSEMREMPDIAPASLSSIHFKDGKSFIELYGDNSHYANHLAAAYPKEAEK"
     misc_feature    complement(21498..21512)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.3"
                     /tool="antismash"
     gene            21692..22597
                     /gene="cyoA"
                     /locus_tag="BP97_RS0117745"
     CDS             21692..22597
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0009486 - cytochrome bo3 ubiquinol oxidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="cyoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016741852.1"
                     /locus_tag="BP97_RS0117745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ubiquinol oxidase subunit II"
                     /protein_id="WP_028550292.1"
                     /transl_table=11
                     /translation="MNFSQTLRWFALLSMMMVLLFLFTGCSDISVLNPKGPIAEQQRDL
                     MLISTALCSIVIIPVLILTAIILWRYRDRKGRKADYSPNWAHSTKLEVIWWGIPIIVIL
                     AIAVITVQFTYALEPSKPIKSDVKPMTVQVTSLNWKWLFQYPEQGIATVNELKIPKGVP
                     IRFEITADSPMNSFWIPQLGGQIYAMSGMAMTLYLQADELGTFWGSGANFTGKDFAKMY
                     FDVDSITQDQFDQWVRGVKADSPALTLDGYRQLAEPSASKVLTYSSFPEGLFQKIVTKY
                     AASHHHEMSVQEDNTMHEHK"
ORIGIN
        1 ccgagaaaag caaaggcggc gctgctccct agatgaacaa aaaagtaggc gaggaaggtg
       61 cctcttgctt tgccgctctc tagaagggga acgtatcttt ttaatataga cggtttagtt
      121 ccttggtggt ggtgcggttt catactaggc actgcaaaaa agactgcaac cgccagcagc
      181 agtgaaaata acccgatggt ccagaatgga agagaccaat tgcttgctgc cagcaggctt
      241 ccgatcggca caccaagcgc ttgagagact gcgagccctg cgtaggcaac gcccagtact
      301 ttactgattt tagccggggg aaacagagtt ggaatggatg cccacacttg cggcgcagta
      361 aacgctgcgc tgactcccgc caaaaaccgg aacaagcaca tagtccaaaa atcaacggca
      421 aacccgcaca agcatgttga aacggcgaag catgtaaggc ctgacaacat tacttttttt
      481 cgatcccatc catcggataa aggtccggcg atcagcgcaa acaccgctga acccaaggtg
      541 taggctccca tcatccatcc tgccatttct gtaggtacac cgaacctatc ttgcagtgtc
      601 ggaagcaagg gagagatcag aaacgtatcc gtaccgataa cgaacatgat aagaaaaaat
      661 aacacgagaa ttttactcat tctattcacc attttctttt ttatttgatc ttgaccccta
      721 ttctagagga taatagtgac aagagttgtc acgaaatata aaataattgg agctagctca
      781 tgtctaaatc gaagcgttta ttggaactga tgatgacggt caatcgaaaa cggaaattta
      841 cggttaaaga gcttgctatg gagtttggcg tatccactag aacaatgtta agggatctgc
      901 aggaattaag tgagctaggg gttccgcttt attcggaggt aggtccgcac ggtggctatc
      961 aggtgttgaa ggaaagaatt ttgccaccca tcgcattttc agaagaagag gctgccgcct
     1021 tgttttttgc ggtatatgca cttcgtcatt attcttcttt gccttttgaa gcggaatctg
     1081 cctccgcact ggacaaattt tatttacaca tgtcggggga cgttcgagat cgtattgatg
     1141 aaatgaaaaa ccgtgtagac tttgtgacgc cgacaagaca gcaggaatcc ccatacttat
     1201 cgattttgct cgaggcagcc gtccaacaaa aggtactgct catccagtac gagccgcggg
     1261 gagaagaggc ggggcggaaa atacaaccga tcggaattta tgccaataac ggcttgtggt
     1321 tttgtccggc ttattgcttt ctgcgtaaag attttcgcat atttcgctgc gatcgaattc
     1381 aatctgcggc atacgatgtt gacggtacgg agcctatgga tctacggcac gtacatcttg
     1441 aaaataagga gttggtattt cagaaggaga aggagtctac ccagctttat gcagaactga
     1501 gccgaaaagg ggtacagatg tgtgaggctg tattatggct gggttcccac ctgaatatcc
     1561 gcgaggatgg cacaggctgg ctggaaggtc caattccaca gagcgatctc gcattttatg
     1621 ccagattttt cataggtttg ggcaatgagg cgacagtcaa gcatcctacg gaactgattg
     1681 attatataaa acgactattc aaagagatca tgtccaacta tgaatagtgc gaaatttgat
     1741 gcgtgacgga agtaatggga gattttttgt aagcgaagcc agttgttgtt aaactaaaga
     1801 aaatggaacc tattggaggc atctcaatga gtcaacgcta tcgaattaca agagcatttc
     1861 aggaaaatgg aaattcagaa caaacaataa cattggaaga atgtaaagaa tattttacgt
     1921 ctaaaccaga tttcgcttat acaccagtat ttactgtgac aggttcaacc agcatgtcca
     1981 ttgagggaga ctttttcatg tggagttacg gtgaggtaaa gatcccattc cgatattatg
     2041 agggagatat ttatgtatcc ggcactaacg aagcagtaat ccccaagatg cttgaggttg
     2101 cgagcgattt gagggcggac gtggcagaag ggtgatttag taaacaaaat ggaaagatac
     2161 tgaggcaaat cataatctta agttattcaa aggggacata tccactaagg tgcgaatcgc
     2221 tacagacgaa tatcagtttg gtactagttt aaattaagcc ttttcacata gtacacggca
     2281 agttaacata tttgtaaaag agaaccaatg atgttgacga actaaccatc tgcatattag
     2341 tcgcttgtaa ccttaagagg aggtacccct atgtacccaa agtatcaaag acgtaacaca
     2401 cttgctttca cagcagcatc ttacttcgcc cttgctgctg gaatattttt atattgcctt
     2461 ggtatttaca atgctgactg gcaattaaat gtaaaaggtt actacttgtt atgtatgttc
     2521 ttaatcatta ttacaagcat agtaacccaa aaggtgatac gggataatgc tgaggataaa
     2581 gaactaaaaa acgaaaatcc aaaacatcgt ttacgtaaca ctcccgcatt cacaggaatg
     2641 gcgatagtgg ggttaataat cggtttctgc atgtttttca ttggattata caatgcaaca
     2701 tttgaattaa acgaaaaggg ctactatatt gccgttatgc ttttgatctc ttatagttct
     2761 atcggggtac aaaaagtgac tcgcgataac gctgaggaca aggagatctt cgagaatcat
     2821 aatctcaatg gataatatca gaaaaacccg ccagtacgat taggcgggtt tttctgatat
     2881 tagcagcaat ccatcatccc gcttggactg ctttcttcat tcgcgatcct gcgaataagc
     2941 ttgtgagaat taatacaaga ttaagcgtca tagcgatggt tatacttgtt tccatgtcca
     3001 agcctgtcga ttgagtgatg gcaataaggg caccgccgat tccgatgaca atccccggcg
     3061 tgaaggaatc ggcaaattgg aggttagccg atacttcccc ggattcacct tctttggaat
     3121 tggcgaatgc gacggcgccg ctagtcggat gagccaatcc tatccctatc cccgtgatca
     3181 tttgaccaat aacggataca gcaattgtag atgttgggat ccagaagaca atgccaattc
     3241 caacaatcat aaaaagtact ccgattatga tccgtttatg tcggccacgg ccttgatctg
     3301 cagtatccca ataggattgc atgaaggaaa tggcgcacca gctaagcgcg gcgcttgcta
     3361 cgactagccc ggctacatcg gctgttactc ccttagtatc tgttaacgac agcactagga
     3421 agttttgtgt gctcgcataa gcagcgaaaa ataatccccg ggacgcaata agagaaggca
     3481 gcccctggcg aagtctcaat gtccctgagg gcagcaactt acgaagcggc tgtatcataa
     3541 aaaccaatcc tacaatcagc atgaggccaa ttgcctttgg aagcataccg agaccgctca
     3601 agaaaattcc ggtaccgatg gcaagcaaga tggatagcca agtggagcct gaggtgcttc
     3661 tttcttgaac agccggaacc tgcagtttac ggaagacagg caagctgaga agggcggcta
     3721 gaagcagaaa gggaagtact ccccaaaaaa cgaagcgcca agacagttgt tgtgcaatga
     3781 cacctgcaac gtaaggacct atcatagatg gcagcacata ggcggtacca aaagcaccca
     3841 atattttcgt gcggagctta tcgggatagc ttaaagagat cgctgtatag acgcaagtca
     3901 tcatggcacc ggcgccgaaa ccctgcaacg ctcgggaaat gatcagaatc agcatatgat
     3961 tcgccatggc agcagcaata agccccaatg caaatagaat catggcgaga gtgaaaggca
     4021 gagcaggtcc tttcttgtca atttgacgcc caactaccaa agtcccaata atttgcgcaa
     4081 gcaagtaagc gctgaaaatc cacccataaa gatggattcc atttaaatcg cccgcaatgg
     4141 caggtgccac cgtaatgaca gctaatcctt cgaaacctac ggccattacc gccaaaatga
     4201 ttccaataga taaggctatg tatttcggtc caaaaatact attttctgtg tcaggcaaaa
     4261 cgatcaacct ccatttgctc agttttttat tatgtatact tcgtatccgg atactttgta
     4321 aacatattac tttacaaaat acaggtgaaa gtttactttg tcaatattta tctttataat
     4381 gtctgtatac ttcttatttc tcattttcgt gtacaaagag ggtgttatta aatgaaaaat
     4441 aacagtcatg ggagagaggc caacgctgaa aaaacaaggc gtaccattgt gaagctgtta
     4501 aaacagcaag gtccttcgga tgcacttcag ctgtcgactg agcttggcat atcaagaatg
     4561 gccgtgaggc agcacttata cgatctgcat gaacagcagt tggtaacgtt cgaggaagaa
     4621 gctagagcta tggggcgccc tgcaaaaatg tggagactga cccaagaggc taatcgactt
     4681 ttccctgacg ggtatgccga tcttaccgtc aacttaattg attcgatgag ggaggcgttt
     4741 ggagaagaag ggttggagaa gctgcttgaa attcgaaacc gcaagcaagt ggtcgaatac
     4801 aagaaaaaag cgccagtcca cttaccccta aatgaacaat tacaggcact tgccgaacaa
     4861 cgtacggctg aaggctatat ggctgaaatc attgagaatg cggacggtac gtattatttt
     4921 gttgaaaagc attgccctat ttgtgaagcg gcacaagtct gttcgggact ttgcagtaaa
     4981 gagttggaaa tgcttcagct cgtcctgggc aatgaggtta tagtggagag aaaagagcat
     5041 atgctaacaa gcggcagccg atgtgtgtat cagatccaac gatgttgtta gcctttgtgg
     5101 aggaaacggc atattacgga aacagtctcc atggcgtgaa agaataaaaa accgacccgt
     5161 aaagaaggat cggttttttg catatcgtct gaatcaaact aacattatgc gaacttattt
     5221 aaaacatctg gtgtccagtc ttttacacca ttatcttcta aaatacctaa tacaacgtct
     5281 gtaatatctg ggtcagcaat caatttatct tgaactcgga attttatatc gtcagcatcg
     5341 gctaatgtga ggcctttgcg taattcaatc atcgcatcga cgtgataata acgtccttct
     5401 tgtgtaatac gaatctcgtt aatgtctatt acatccttat cggaaaggat tagcatcgct
     5461 actttttcag ctacatcgcg aggggcagcc acaccgatca aaccaatcat attgtcatat
     5521 ccaactcgaa atgcaacgcc gaccatcaat aaaccgatga ggatagttac gacaccatca
     5581 agagcttcaa atgtggttag agaagttatt aataccgcca tcatagctaa tgccgcaccc
     5641 gtgacagcaa caagatcctc gtaaaatacc aaacgagtag ggggggctga gcgacctaca
     5701 tgtttaaagg atgcaacaat aaaacctaac cctctagttt caactcttgc ttctttcata
     5761 atttccttca tagcttttaa taagattaga ccgtcaacaa caaggttaaa cagtaatgct
     5821 acaatattta accaaattcc ttgaccagct tgaactggat gatgaatcaa atgccatcct
     5881 tctcgaaccg tttcgtaagc catgatggat acgacaataa ccgcaatcat acaaaagatg
     5941 ttaataactc gaccaaatcc agttggaaat tgacgagtag gttttttctc tgcaaggatg
     6001 ctacctacaa acacaaaacc ttggttaata ctgtccgcca atgaatgcat tgcagaggca
     6061 aacattgcac cgctaccact cattgaagca cctacacctt tggcaatggc aataaaggca
     6121 ttaccgatca tcgcaatagc ggatgattta tttcctttct taatcaagct caataaattt
     6181 tctcgttccg ggtccgggtc catttcttcc tccttaaaat ttggaaatcc ttttgaatat
     6241 tacctaatcc acatctgctt taaactcttg ggcttagata tcaataatta atacgagcga
     6301 atattacagc agtttcactt aacaaaaaaa ttttcttctc tatgtattac cgaaattcca
     6361 agtaactcaa aaagcttgtg tgccatatac acacaagctt ttatttatcc atttctttag
     6421 cctacttcac gccctgttgt accttggtac ctatgagaat gtggaaaacg tccgtttact
     6481 gttgtaaacc cttgaaaata gtggtaatgt ccaccagtag ggaagtcaat agcagggcca
     6541 gtaactccac gaaggttatg tgtatgcccg tcatcaagcg aggtaacagc gtaataatca
     6601 tgtgtatgtt gaacaccact agcagcaggc tcggtcattc cagcataatg atgatcatgt
     6661 cctgcatcaa atgaggtaat ccctgaaaat ggatgtgaat gaacaggcct cccatcccaa
     6721 gaagtgatat acaatttgtg tgaatggtct gactcagaat catttgagtg aaagataaag
     6781 cctgtaatag gtatctccat aatacacacc cacgctttct atgatatttg cctatccata
     6841 atatgaatgg ggaagacgat tggatactcc tccatccggt gaatgaccaa aatcagcttt
     6901 tttgggtaat gactgaagaa attttccaaa gtaagaattc tttcacactg gttagggcaa
     6961 gatactttgg ggaactgcaa ctgcgagaag aagcatttcc taatacagtg tgagggagtg
     7021 agatgaatgg taaagaacaa tgagcgtaat cgtaatgatg attctgccca agaaacgact
     7081 gagatggctg gtgctgacgt aggcgaagct gtaggaacag caggtggcgg tgctctagga
     7141 gcaatcgtag gctctgcctt ggggcctgtt ggtaccgttg taggtggtat agtaggcgca
     7201 gctgttggta acaaggccgg cgagaacgtt ggagataatg aagctgcaaa tgataataat
     7261 cagaaagatt aacatgatgt gagaaaaaaa ggtgcaggtg aaatcctgca tcttttttta
     7321 ctaacttctt acattccaag aatcgaattc ttaaaaaccg tgcctagacg gcttttttta
     7381 ttttaaggga ccaaatcctt gtctaaatta agacaagaat ttggttattt ttttgagcaa
     7441 agagaagcgt ttaattggca tttggtacaa acgcctataa aatgggcgtt tgattcagta
     7501 acaaatgcgg agatactcca taaattggaa ttatgttcat caagagcagt tgagccttcc
     7561 attatgctca taccaactag aaaaaattat tggaggtttt taaaatgaat gaattccaaa
     7621 atgatcttca acaattaagc gtttcttccc aatttcaatc cagtgagatg acgccttgga
     7681 gccaacaaag ccaatatcca gaaggtcagt atccctatgg agtgaatccg gtggatccag
     7741 cacggttatg tattggtttt ggtgtcggtt tttgtgtcgg cttttgcggt ggtttttgca
     7801 ctggcttctg tggaggttgc ggcggctgcg gaggctgcgg aggttgcggt ggattccgct
     7861 gcggaggttt tcgttgtggt ggattccgtt gcggcggctg ccaccatcgt tgtcgctaat
     7921 cgtttcgtct cgctgaaaac cctgcccctg caacgacaag ttgtcagggg catttattca
     7981 ttatgggcaa tggcatgtgg gacgaattga tgtacatata ttactaggag agcgattcta
     8041 caaattggca ctatgtacca tttaggagga gtgaaatgac aaatttaacc cctgctgcac
     8101 gtctgaaagt aaaggaggac acgttttttc tccctgttcc gaacgatgcg gtgtatttcc
     8161 ggaataatgt aggcacattt cggatggaag gcgggatgat cgagcgttgg attgaaaaat
     8221 tagttcctat gtttaatggg gagcatacat tagcggattt aacgaacgga ttatcgcacc
     8281 cgcatcggga acgggtttac gaaatcgcga acgtgttgaa ccagaagggc tttgtccggg
     8341 atgttagtaa agacaggccg catcaattat cgaacgagat tatccaaaag ttcgctgctc
     8401 aaatcgtatt tttagaaagc tttggcgatt caggggcata tcggtttcag agttatcggc
     8461 agactggcgt actagcagta ggctctggtc cgttttttgt cgggttggtt tctgcattat
     8521 tagagtcagg acttccaaag atcaatatgt tgataacgga atccgagcca acgaaccgag
     8581 agcggctggc agaattggcg gatcaagccc gtcttagtga tcctgatgtg gtgcttaagg
     8641 agattaataa acgaaaagaa ggagcagacg gttggaggga cgctgtacaa ccatatcaag
     8701 cgattttgta tgtatctcaa gttggagatt tagaggagtt ccgactcctc catgcagttt
     8761 gcaaagcaga gaagaaagtt ttgcttccgg ccatgtgcct tcatcagaca ggaatggcag
     8821 gtcccgtcgt gcatccagag tatgaagggt gctgggaatc ggcatggcgc cgagtccacc
     8881 aaacggctgt tcacaagaat cctgagcagc attctttctc aaccactgcc gggtcgatgc
     8941 ttgctaatgt gattgtgttc gagcttttta aaaaagttac tggagaaact gagctaagaa
     9001 actcgttttt tctgctgaat ctggaaacat tggaaggggg ctggcatcca ttcataccgc
     9061 atcctttggt acacgggttt gcgaagccac aggcggatcg agcatcgaag ctgcaatttg
     9121 acgggaaaga ggagagttcg gacccagatg catccaaccg tttgtttact tatttgaatc
     9181 aattgacttc accgcaatcg ggaatcctcc atatttggga agagggggat ctaaagcaac
     9241 tcccactttc ccagtgccgt gtccaggcgg ttaatccgct ttcggaagga ccggtcgaaa
     9301 tgctgccgga gatgcttgga acaggtctta cacacgaaga agcgcggtgg gaagcagggt
     9361 tgattgggat tgaagcgtat gtagcccgct tggcggaaat gctcgtgcct actaaagaag
     9421 ttatgggaat cggtgtagga ggaactacgg cagaagcgat gttacgtggg ttacaagcaa
     9481 atttaaccga acggttggct gcacagcagg aagttcggaa gccatatgtc acacgggtgc
     9541 agttgagcag agtggaagat gaacgatgtc ggtattatat gcaagctttg actgctatgg
     9601 ggaaagaacc ggtgattggc ttgggcgagg aagttttggg attccctaca gtttgggtcg
     9661 gtacaactga ctattggtat gccagtaccg gattaaataa aacaatggct ttgcagagag
     9721 cacttaaagc ggcgctgcag aaggtacaaa atcaatccgt atacccagcg catcacgtgc
     9781 tggaaaccgc atcggtgcga attggaaacg aaacgatgtc tgatctcatg attccttcga
     9841 gtgaaggaac tgcacaatca cagacagcat tacaggaagc tttggagatt ctgacgaaga
     9901 acggcaagca gctctttgtt gtggatctag ccgtggagcc gtttttgaaa gaagggctta
     9961 gtggtgtata tggtgtgctg cttcgagagg gggaatcccg gtgaacgtag gggtagctat
    10021 tattggcgag ggaggattgg cggggctcgt aagtaaagag atgtcctccc tatgccaggt
    10081 tgtgcgtctg aacgatttta aggaagaagt tcctgaatcg gtcgattttg ccttggtact
    10141 gcacgatgca tggcatcctt ctgttcatcg ggaggcggaa gagatgttcc gggcagcagg
    10201 cattccatgg ctgcgaggct ttgttacctt cggtgaaggt gtaatcggac cactggttcg
    10261 gccaggggtc tccggttgct cgcattgtgc tgacacacgc catctcatgg cgggacgtga
    10321 ccgcaaggaa atgtggatgc tggagcagcg tctgactgag gcagggggaa ttcctcacga
    10381 tgcttgggca tcgcgtactg gacttttaca gatgacacat ctgcttgtta aagagtcaca
    10441 gaaggtaatt cagggcaaac ggtctcaatt ggaggaactg atgtttttcc ttgatctgaa
    10501 aacattgacg ggtaaaactc atttcttttt gcccgacccg ctatgtccga catgcagcta
    10561 tttgatagaa gatacgccgg agagggcgtc cattttgctt caaccaagtc ctaaaatcaa
    10621 cagaaaaagc taccgaagtc gatcattaga ggatctggcg ggatttttag ttaaagatta
    10681 tttggattat aagaccgggt tcttgaatgg aaaaatggtt gatcttgttt ctccttttgc
    10741 cgatgtgagc gtaaatcttc cgatgtttga tcaggatgag ccaacggctg gccgtaccca
    10801 ttcctacgcg gagagcgagc tgacagctat tatggaggga ttggagagat attgtggaat
    10861 ggcgccccgt ggcaaaatgc cggtgatcca tgatagttat cgtaatctgg cgaatcatgc
    10921 ccttgatcct tcagcagtag gcttgtatgc gaaggaacaa tatgagcagc cacattttcc
    10981 attcaagccc tttcactctg aagagcctat cgactgggtg tggggttatt cattcgagag
    11041 acaaagtccg atattagtac cgcaacagct agcctattac agttctccct gcggacatgg
    11101 gtttatctat gaaacgtcca acggctgcgc gttgggtgga agcatggagg aggcaatatt
    11161 ttacggcatc atggaagtgg tggaacgaga ttctttcctg atgacttggt atgcgcagct
    11221 tccgctccct cggcttgatg tacattctac cggtgattcc gaattggagc ttatgatcaa
    11281 ccgcttgcga acggtggcag gattcgatgt gtatttgtat aacgcgacta tggaaaatgg
    11341 aattccgagc gtttgggcgt tggccaaaaa catgaaaccc aaaggggtaa atctcatttg
    11401 cgctgcagga gcacatccgg atccggttcg tgctgcgaaa agtgcggttc acgaattatc
    11461 tgggatgatg ctgacgctcg atggaaagtt cgaagaaaac cgagagagga acgtgcagat
    11521 gttccacgat ccgtggttgg ttcgcagtat ggaggatcat tctatgctgt acagcctgcg
    11581 ggaagcagag gatcgtcttc aatttctact ggaagataac cgacctttaa ggacattcca
    11641 ggaggaattc aaacaagcgc ctgaacacac agatctgacc gatgacctga aggctgcgct
    11701 ccaatcgttc caccggttga agctcgatgt gatcgtagtc gatcagacga ctccagaatt
    11761 aaaacgaaac aatctatatt gtgttaaggt gctaattcca ggaatgcttc caatgacttt
    11821 cggtcaccat ctcatgaggg tgacggggtt ggatagagta ttaaaggtac cggcactact
    11881 cgggtatgta aagcaaccgc tgctcttaga acagcttaat ccgcatccgc atccgttccc
    11941 ataaaacgac ctaggaggaa ggaagatgag tctggaaaaa ttcctgggca gccttcattc
    12001 ggatagcgat gatttcaagc cttcggattg ggaagtcgat tgggatgatg cgccgctaac
    12061 atataagcta taccgcaact tacctgttat tccactttcc cctgagctgc cattgtctct
    12121 ctatagatat aaatcgcccg ccaatcctga tctgacaacc atcggtcaca ttctctggca
    12181 tgtttatggt ctaacccgaa taaaccagtt acctacatat tcttccatgg gctatacggg
    12241 cagccctgta cagatgtacc ggcggtttgt cccttcgggc ggcggtttgt acccgaacga
    12301 gctatacgta tatttgaaga cagcggatgc tcctgtagga gtatatcatt atgacgcggc
    12361 gcatcatcgg ttggttttgc tccgcgaggg cgattttgat tcctatctga cccgggcact
    12421 aggtaatcga tgcgacatat cgggttgttt tggaacggtc tttacttcag tcatgttttg
    12481 gaaaaactat tataaataca ataactttgc ttatcgccta caaggactag acactggtgt
    12541 attgacgggt caattactcg aggtgacgag acggttcggt tatgaatcaa gtgtatattt
    12601 tcaatttctt gatcgagcag tcaatcatct gcttgggata accgatcagg aggaaagtgt
    12661 atatgctgtc attccgcttt cggccaaacc aacagcaaca agacttaatc aggggatcgt
    12721 cgaattggcg ggaagctctg ccgttgaatt gtgcagggaa cttccagtca ttcggcacga
    12781 gcactacgta cggtcgctag aaatcaagga gtacccgatg ctgaccaaga tgaacgaagc
    12841 ttcaatgtta gattcaacca gttcttttgg atatgttaag gcggtgaagc atgttgaaag
    12901 cgggcttcag accgtattca tgccccgtgt ggatcggtta acgtatgatt tagcatccgt
    12961 ctgccggaag cgagcttcgc cagagtcgaa tttcgtattg agtaaggtga cacagtcaga
    13021 agtggcgact ctcctgcaag aagcgacggc ttctttgtcc tataataatg atttgaatgg
    13081 taataatgaa aatcctattt cacgtatttc cttatactgt tgcttgtata acgttgatgg
    13141 cattccaaac ggagcttatt gttatgatag tgaggctcat ttgttacgcc gagtacggcc
    13201 aggagatcaa cggctacggt tacagaaggg aatgtcgttg gataacgtga atttgtttca
    13261 ggtaccaatg tgcttgcatg tagttggtga caaggactac cacaaatcgg tattagggta
    13321 taggggatat cgaatacagc agatggaagc gggtatgctt gtacaaagct tgttattagc
    13381 ggcgtcttcc atcggattgg gtgggcggcc attgctcgga tttgatcctg ctctttgtga
    13441 cgaactttac caattgactg atcaaggaaa gactaccctg atccaaattc cgatcggtca
    13501 ctatcgttat cgtgctcttt tggaaggcag cctgcacagt tagtcagaaa cgcttatcat
    13561 ccaaccaatg atttgctaat cttactccac cagtaatgtt ataatcatag aagattaact
    13621 tttcttggac atggattatc gaaagtggtg aataggattg gatacattgg agtaccagat
    13681 cacagacgag tgggacgaaa cccgttggat caccgtggag caaatctacg aacaagcgtt
    13741 tccgcttgac ggcaagaaaa gtcgagacat cattcgtcgc atgtttgaaa aacgtatgtg
    13801 tcagctgcac acaatcgctc aaggatcaga aatcgttggg atggcgctaa ctggaatcga
    13861 taaacaagca gacgctttgc taatcgatta tttagcggtt cgtactgatg ttcgcggcag
    13921 aggttacgga cgattactgc tggaccgaat caagcaatgg acgcgtacgg ctgcgggctg
    13981 caaaggaatt attgttgaag tggaatccga accgacggag gagaatagcc ggcgagtcca
    14041 tttttgggaa atgaacgggt tccatcttac tgcttatgtt catcaataca tttgggtacc
    14101 tgagccttat caggcaatgt atttgaactt cgatgagatg gatcggttgc ctgaggatgg
    14161 gataatgtta tttcgcagta ttacacggtt tcatgaaaag gcgtatcgtc gtaaataata
    14221 gtgtcccccc gataacaaag aatgaatcac aaatgaatat tctgtccata ttaactgtgg
    14281 tgtgaattat taaggaggaa tattcaatga cagaccaaca atcgaatcaa catgagcaaa
    14341 gtgcaagaac caaagctcaa aatgagttga atcacgcact ccacgcgctt aacgaagcaa
    14401 ctcatagtaa tgtcaatcga gaacaagacg ttcaggctgc aaaagagcag ctgcaaaaag
    14461 cccaattgga acatatgcag gctaaagttt ctgacagcca agactcactt tcttaaacga
    14521 taattgcccc cccaagaggg ggtgttttta tatacaaaag tcctacaatg cagaaaatga
    14581 atccaggcag ttgacatact tgttgtttca aggatattat agatacaata agtctttgta
    14641 ttgaggtgtt attatgagat ttacaaaagc gaccaattat gctctgcata ctatgctctt
    14701 gcttgttgat gcttcttcag cgaagccagt tggcgttcag cagttggcgg aatctcaagg
    14761 tgtttcaccc acctatcttt ccaaaatttt aacgaggctc gtgaaagctg gaatgatcga
    14821 atcgatttcc ggggccaacg gaggctatcg attatcccgc aaaaaagacg acattaattt
    14881 tttggatatt atccatgcca ttgaggggaa tgcctccttg tttgaatgtg attttgtcca
    14941 tggcgacgaa tgcttgattc aagctgttat gaaggaagcg gaagagaaga tggaggggca
    15001 tctcaagaat acaaaattga tggatctggc caaaaagcaa acgcaagttt aaggagaacc
    15061 atgttaggtt gaatgaaaga ttaagattct ctaagtgtgt taagtatttt ttggttttat
    15121 tatagatata aagaatctgt aatatctatt ataggagatg atcattatga tttacgattg
    15181 cgcgataatt ggtggaggcc ctgccgggtt aaatgctgct cttgtactcg gtagagcaag
    15241 aagaagcgtg gctttgttcg acaataatcg ccccagaaat gccgttacac atgcatctca
    15301 cggctttatt acgagagacg gcgtaacacc ggcagagttc cgccgcgttg cctatgagga
    15361 ggtactgcga tatccttctg tcgatcatct gcaaaccgag gttgttacgg ttagtaaaat
    15421 cgattccgga tttgagatga ttgattcatc aggcgttgta actcgagctc gaaagctgat
    15481 tttggcgaca ggagttaagg agatatttcc cgaaattgaa ggtttacatc cgttgtatgg
    15541 gaaaagtttg tttaattgtc cctattgtga tggttgggag ctacgcgatc aaccgcttgt
    15601 cattgtttca gaacattcgt cagtttttca tacggccaaa atgctccaca actggagcaa
    15661 ggatttaatc gtctgcacga atggccaggt gtctttgtcg gatgagcaaa aaaagcggct
    15721 tctatcaaaa gggattgatg tgatagaaaa acctatagcg gctttcatag gtaaagatgg
    15781 ccagttagaa catgttcgtt ttgccgatgg gactcaaatc ccaagggctg gtggcttcgt
    15841 ggctcccaaa tttgtgcaaa gcgcaccgtt cggcgaacgt ttgggctgtg aaaggacgga
    15901 gttaggcggg atcaagaccg atcattcggg aagaacctca atacctggtt tatattctgc
    15961 aggagatgct tcgtacttca tgccttccca attaattttt gccgcggcag acggcagcag
    16021 aactgctatg ggggttaata tggatttgac ggaagaagat tttgaataac aatgtaatgt
    16081 gtcccttatt catgacacaa atgttcctga aaaatgaact ctcctaaagg aattaggtat
    16141 ttctcgacga aatattttac ttgagagact tatctgaatt agtccagcaa ggagtgtgtg
    16201 gattatggaa gtatttcgaa actgggcagg taactataag tacagcacct cgcaccttca
    16261 tgttcccgaa aatacggaac aagtacaaga attagtggca cgctgcggcc gaatcaaggt
    16321 gcttggtacg cgccactcat ttaatggaat ctccgattct actgaaaatc tgctctcttt
    16381 gcagaagctt aatcgagtga ttgcattaga tcgcactagc agtagagtga cgatcgaggc
    16441 cggtgtccga tatggtgagc tatgccaata tcttcacagc aatggctatg cgctgcacaa
    16501 tctggcttca cttcctcata ttactgtcgt aggtgcatgt gctacggcaa cgcatggttc
    16561 cggtgatctg aacggcaacc tagcgacagc agttcattcc ctggaggtca tcaaagcgaa
    16621 tggggagacg attgtcttct cacgggatca acaagacggg gtcttcgatg gaaccgttgt
    16681 aggactaggg ggcctgggtg tagtcaccaa aatgactttg gatatattac cggaatttca
    16741 gatgagtcag caagtatatg acaatttgcc tctggtacag cttaaagacc atttcgatga
    16801 tatattttcc agtgcttaca gcgtcagtct atttactgat tggaagaatg cgacattcaa
    16861 tcaagtgtgg ataaaacaga aaacaacaaa tcaatcctcc gatccgatgg agcctgagtt
    16921 tttcggagcg gcacgggcaa ctgcacgacg acacccagtg ccaggtcaga catcagagaa
    16981 ttgtaccgaa cagatgggca ttccaggacc atggtacgaa cggatgccgc attttcgcat
    17041 ggatttcacc ccaagcgccg gagaggagct gcaaagcgag tatttcgtat cgcgccatga
    17101 tgcatatcaa gcattgtgtg cgattgacca gatacgggaa tacatatcgc cactgctcta
    17161 tgtttccgag gttcgtacga ttgcaaaaga cgagctgtgg atgagccctt gctataagca
    17221 ggaatctgta gctatccact ttacgtggaa gcctaattgg gaggcggttc aaaaagtatt
    17281 gcctatcatc gaggaaaagc tcgcgccttt ccatgctcgt ccacactgga gtaagctctt
    17341 tgccatgcag ccggagcaac tgcattccct ctatgagaag ctgcccgact ttcaacagct
    17401 gctccttcga tgtgatcccg aagggaaatt ccgcaatgac tacttgaata aatacattat
    17461 ggggaactaa ttccttggtt atttacttta ttgtatagag taatcaacaa tacgaagctg
    17521 ccgttgagaa gaacggcagc ttcgttgcgt ttaaaaacgg caggatagtt cggttattat
    17581 taaatattct ctggtcatct ttgggtatgt tgatactatg gatagtgatt cgtgagaaaa
    17641 tcactttaat ggactggagg ggtggaattt gagtaatcag gactggatca aaccctataa
    17701 gttggtggaa taccatgcag aggctttgtt tacacatgac cataacttgc ggctacgcac
    17761 gataaatgaa ccctggcccg gagctgccga tgctccacgg tttttcttgg gtcgatctat
    17821 tgagggaacg actctcagtc gattccggta tgatgtacag gagaagcttg tcaggcaatt
    17881 agaaggactt tgcgctgacg aaccaattgt gacagatttc cagacgaagc caaaacattt
    17941 tgaagcgtat atgaacctcc tccaagggaa aaggttcacg atgggaccat gttatcttgt
    18001 tcctagagag gccgcatcta caatgaaggt agtcaacgtc aaccgggaaa atatgaagga
    18061 attgttgggc ggaaatttcg aatggatgac ttcagaaata gactacgcgc agccttgcgt
    18121 agcgctaata agggaaaacc aggctgtctc gatttgccga agtgttcgca tcacatccat
    18181 ggcacatgaa gctggtcttg agaccttgga agagtttcgt ggtataggat atgctgcttc
    18241 agttgtagcc ggatgggcaa tggaggttcg gaaggtagga ggtttaccgt tatacagtac
    18301 ctcgtgggac aatcttgcat cccaaagtgt agctagaaaa tcagcattgt ccttttatgg
    18361 agtcaatttc acagtttatt gaaccgtttc gtatagggag atgtgtttaa tcctatttga
    18421 ggtagcgggt agaattagag aagcgtaaat gtgataaaat aaaggggaaa tcaaactatt
    18481 ttgaattagg agaattaaat gtgagcataa ctatcagaaa agaactatta gatgattata
    18541 aattgactga aagaatcata aagaatgcat ttgctaattt agagttcagc gataaaaaag
    18601 aacatgaatt ggtggctcga attagaaaat cagatgtttt cattcctgaa ctatcattag
    18661 tggccacgga caaagataat aatgagatcg ttggacatat acttttatct aaaataaaaa
    18721 ttattaatga taatcaaagt gttgaatcac ttgctcttgc tcctgtttcg gtcttgccaa
    18781 attaccaaaa taaaggcata ggagagcagt tgattcttga agcattacaa aaagcaaaag
    18841 aatttggata ccattctgtc gttgtactcg gacatccaca atattacccg aagtttggct
    18901 tcaaaaaagc atctttatgg gggataacgg caccatttga agtgccagat gaagcattta
    18961 tggcgcttga gctgcgtcaa ggaactcttg ataatgcttc aggagttgtt gagtatccaa
    19021 gtgttttctt tgattaagtt acgattacaa tcttaattgt cgtttccagt atattgccga
    19081 aggatagtcg tcggatcgaa gaagctcatt attctctaga ggccatcatt aatactgaaa
    19141 aaagacataa accattcttc aatgggaagg atgatttatg tcttttttgg tattcataac
    19201 ttttatttat acatagaaca aattatatat tattaatgga tgcttggtct gtgtatactt
    19261 gagctacaaa ggaggttgaa acatgatcaa ctacacaaag tatatgagaa aaagcatatt
    19321 atcgctggtc agtttagctt ttctgtttat gtctactgct tgttctggag ccattgatgc
    19381 aaaaagcagc tctgcacaag cggttgacgt tgatgtaaaa acggttcagg aagtgctgct
    19441 acctggacga gcaattctta tagacgctga cgtagcccaa gggaataata aggtaaagga
    19501 tgcggatgat gtcaaaatag aaatttggaa aaaagatagt gacaaccata aaatgattac
    19561 tgcaactcat tggcttgacg gcacttaccg tactaaaacg ttattttcgg aaagtggaac
    19621 ctattatatg cgagcgcacg tcaaggatca aagaggggat gttacaacta ccgaacagga
    19681 attgttcgtt aaagatgtac ttccttccga gagtcaaata aagtcttgaa tcatcgttta
    19741 actataaatt agatagctca ggaactctat ggaatcacca tttccaagag ttcttttaca
    19801 taggtcgggt ttcatttaag ctttattttt aagaactata gaaataaaat cgcgaatata
    19861 tccttccaaa taagccggtt catgtgaaca aagtacgatc ttattcgtaa gccggattcc
    19921 gtcaacctca acctttgcca gctctccacg cctaatgaat tgacttgcta caagaagaga
    19981 aacataactg accccgtatc ccgctacaac agcttgaatc gtttcattaa gtccattaaa
    20041 ttgcaattct atacttggag gactcacgtt ctgggctgtg catacttcaa ctagcctttt
    20101 tcttgtggtg ctaccttcct ccctcatgat aaacggttcc ttgatcattt cctcaattga
    20161 aatatgctgg ttggcatatt tatggttggg agcaaccacg aaaacaaatt catcactgta
    20221 taattccaag cactgcagag agtggttggt ctgtgtcgtg atattactgt tcccaaaaat
    20281 tgcgatatct acttcgtaat tattcaagct ctcaaatgcg ttttgtgaat taacagtcga
    20341 gatttcgact tctacctgag aatatttttg tttaaaaaga gaagcccacc tcgggataag
    20401 aacacttgtt gcaagataat taccggagat tctcagcttt cctttgggat gactttggta
    20461 atcttcgatc atgccttgaa tttgctcttc caaaataaat agcttttccg taggtttaaa
    20521 cagcttttgc ccaaatgggg ttagaaccaa gtttcgaccc tttttctcga ataaaatgat
    20581 accatattgc ttttcgaaat ttcggatttg ggctgaaata gcgggttgac tgatgttcag
    20641 ccttttggat gcctctgtaa cacttccggc tattgcaaca tgataaaaca acatcaaggc
    20701 atgcagatta atggacattc gagcaccttc tatacattct attaatatat aatataaaac
    20761 ctatattatt attttatgca ttacgaaggt atacttcaag taattgggaa aggggatgcg
    20821 ttatggatag cacatcagtc tacctcgtta gacatggaca gacggaatgg aatgtggaac
    20881 agagaatgca agggcacttg gattcaccct taactcgaga gggccaaaag caagccgctc
    20941 aactgcgaga ccgattaaag gagatgaagt gggacgccat attctcaagt tcaagtccga
    21001 gagctgtcca aacagccgag ataatttccg gaatgaaccg tgagcatgtc agacaattgg
    21061 atgcattcaa agaaatcaat atgggcctgt gggagggcca gctcttaact gaaatacatg
    21121 ggctttacac aagggagtac ggacggtttt ttgaagagcc acacctatat tgcccgactg
    21181 aaggaggaga gacttacttt gagttgttgg tacggggcgt atccgctttg gaagatattt
    21241 taaccgcttt taaaggggga aagattctta ttgtaactca ccgtatcact ttgaaagtca
    21301 ttatgaacta ttactttggg aacacgctaa gtgagatgag ggaaatgcca gatattgccc
    21361 cagctagcct aagcagcatc catttcaaag acggcaaatc ctttatagaa ttgtatggcg
    21421 ataattcaca ttacgcaaac catttagcag cagcctaccc caaggaagct gagaaatgaa
    21481 tagtgctaag aaagttcaac tgtcagaaaa ttggctctcc tgtggtgggc tatttttttt
    21541 ggaaatatga ccaaatcatg atcaaatgat ctcaaaatgt tgaacttgga gggtggaatt
    21601 gtgtcctcaa gcggttggtg acacttttgc cgctctcttt tagagtgaag cttaatgcaa
    21661 gccatactga aacaaggagt tgagacacaa catgaatttt tcccaaacgc tgagatggtt
    21721 cgcattatta tccatgatga tggttttgct gttcctcttc actggatgtt ccgatatcag
    21781 cgtacttaat ccgaagggac ctattgcgga gcagcagagg gatttgatgc tcatttcaac
    21841 agcgttatgc tccatagtca ttatcccggt actcattcta acggccatca tcttatggcg
    21901 ttatagggat agaaagggca gaaaagcaga ctattcgccg aattgggcac acagcaccaa
    21961 gctggaggtt atctggtggg ggattccgat tatcgtcatt ctggcgatag cggtgattac
    22021 cgtccaattc acttatgcgt tagagccttc caaaccgata aagtccgatg tcaaaccaat
    22081 gaccgttcag gtgacctctt taaactggaa gtggctgttt caatatcctg aacaagggat
    22141 agccaccgtg aatgagttaa aaattcctaa aggcgttcct atccggttcg agataacggc
    22201 tgattctcct atgaattctt tttggattcc tcagcttgga ggacaaatct atgctatgtc
    22261 cggcatggcc atgacgcttt atttgcaagc ggatgaatta ggtacatttt ggggatcagg
    22321 cgccaacttt actggtaaag actttgcgaa aatgtatttt gacgtagact ccataacaca
    22381 ggaccaattt gatcaatggg taagaggggt taaagcggat tcgccagcgc ttacgctcga
    22441 tggctacagg cagttggctg agccttccgc ttctaaggtt ctgacgtact cttccttccc
    22501 tgaaggattg tttcaaaaaa tcgtgaccaa atatgcagca tctcatcatc atgaaatgtc
    22561 tgtacaggaa gataacacta tgcacgagca taagtaagct gtaggaaagg agaaataact
    22621 tcatgctgga tcatgccaaa agcttcgcct cccaattttt cgtaaccggc gatccgttga
    22681 tttatggtgc cgatgtaagt atcgtactga ctctgttggc tattttattt gcactgactt
    22741 atttcaaaag atgggggtgg ctgtggcgag aatggctgac aacggtcgat cacaagaaaa
    22801 tcggtatttt gtatattctt tccgcttttc ttatgttgtt tcgcggcggg gtggacgctc
    22861 tactaatgcg aacgcagctc gcgatgccgg agctgggatt tctgcagcct gaacattaca
    22921 actcgatatt caccacgcat ggcgtcatta tgatattgtt tatggctatg ccctttatgt
    22981 tcggtctatt taatgtggtg gtgccgcttc agctcggagc gcgggacgta gcgtatccgt
    23041 tcctgaatgc actcagcttc tggctgttct tcgctggagc catgctgttc aatctgagct
    23101 ttgttatcgg cggttcgcca gatgcaggct ggcttgctta cccgccttat tctgagctga
    23161 tgtataaccc tggtgtcgga caagacttct atatatgggg catccaaata tccgggatcg
    23221 gcagcttgat gaccggtatt aattttatcg ttaccattct aaagatgcgt gcaccaggca
    23281 tgaagctgat gaaaatgccg atgttcgttt ggtctgtact ctcgagctgt attgcaatta
    23341 ttttctcgtt tcccatcctg accgcgacat tggcgttgtt gtttttggac cgatatgccg
    23401 gagcacactt tttcacatta gatggcggcg ggaatcccat gatgtacatt aacctgatct
    23461 ggatgtgggg acatcccgaa gtctatatta ttgttctgcc ggcgttcggt attttctccg
    23521 aagtagtggc gaccttttcc aag
//
