LOCUS       NZ_ARPF01000024        26868 bp    DNA     linear   CON 18-FEB-2024
DEFINITION  Streptomyces sp. SolWspMP-sol2th B083DRAFT_scaffold_21.22_C, whole
            genome shotgun sequence.
ACCESSION   NZ_ARPF01000024
VERSION     NZ_ARPF01000024.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. SolWspMP-sol2th
  ORGANISM  Streptomyces sp. SolWspMP-sol2th
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 39385)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Improved High-Quality Draft of Streptomyces sp. SolWspMP-sol2th
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 39385)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces sp. SolWspMP-sol2th
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/18/2024 03:17:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,475
            CDSs (total)                      :: 6,400
            Genes (coding)                    :: 6,297
            CDSs (with protein)               :: 6,297
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 31 of 103
            Pseudo Genes (incomplete)         :: 82 of 103
            Pseudo Genes (internal stop)      :: 12 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:24:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 12517
            Orig. end                         :: 39385
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ARPF01000024.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..26868
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="linaridin"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="(cypemycin or cypI)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..26868
                     /SMILES="C(C)C(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cypemycin or cypI)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="linaridin"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10609](+)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10609
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     misc_feature    1314..1323
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(1762..2244)
                     /locus_tag="B083_RS0129885"
     CDS             complement(1762..2244)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487265.1"
                     /locus_tag="B083_RS0129885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028419783.1"
                     /transl_table=11
                     /translation="MSTSDQDRVRTRREGRDRGTDTPIAEGTTAQAPEDTAGDTRTDAT
                     RNGADAPDGADSADGAEIAGDDRDGEVDGERRLTPRQARRLRIVLSSVGMIAMGVVLAL
                     RIASRSSVLVVGVYGLALILCGVVIELSRNGRTRLGSWLLGAGLVAAVGADWLLLP"
     gene            complement(2329..2808)
                     /locus_tag="B083_RS0129890"
     CDS             complement(2329..2808)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513195.1"
                     /locus_tag="B083_RS0129890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF309 domain-containing protein"
                     /protein_id="WP_028419784.1"
                     /transl_table=11
                     /translation="MDETSRDRDTEGRARNARPRDGLGRPLPYGSPGVERQPEGVVRTP
                     DETLREAQRLLDAGMPFHAHEVFEDAWKSGPRAERELWRGLAQLAVGLTHGARGNRAGG
                     ARLLRRGAGALSSYGGAWPYGIRGGGLVDWAHELADRVEAGRPVDAEAEAPRLLG"
     cand_cluster    2534..26868
                     /SMILES="C(C)C(=O)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2534..26868
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[22533:>26868](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22534..>26868
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     gene            2919..5573
                     /locus_tag="B083_RS0129895"
     CDS             2919..5573
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513194.1"
                     /locus_tag="B083_RS0129895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_028419785.1"
                     /transl_table=11
                     /translation="MKPSRPLYEREPELAAAARAVDDLCGAQAVGGLLVFSGEAGLGKT
                     ALLAEIRTMAADRCTIWSARGGETVTSVPFHVVRQLLQPALDQFPPDETRALFGDWYDT
                     TAPALGLAEPSGPQPDPQGVRDGLDFVVARLASRLSHRPLLLLVDDAHWADGESLTWLS
                     SFTARLGELPLLVVQSYRPQEMAERNASYVADRAAERDAEGDSNVTRVALRALTPDATA
                     ELARAALGEHADDPFCREVWAVTGGNPYEAVELVAKVQDQELAPVEESAGQLRELGASA
                     RGSGLVARLERLGTNANRFAWAAAVLGTDISQELAATLAGMSSAEAADCTARLRDARIV
                     SGFDPLEFVHPLIATAVYRSIPPATRTAMHGRAAWAITRAGLGAAAASRHLLEVHPDDD
                     QELVAQLREAAGQHLAVGAPEAARRCLERALEEPPRPKDRAVLLYELGCATLLSSPPTT
                     VQHLRAALDMPGLDDGLRVDATFRLAAALAHNNQLKDAALALAAEAARTAPGPGLMRLQ
                     AAHFMWEGMQAAEDDGPARSRRLTRNADHLKGRDNAERALLTLRAFDAMLRGENAQLIV
                     DLCERALVDGSPARGLGWTDSEWGFELPTMVGITYAFTDQLDRADSLFGEAVRAFEISG
                     WSGAHLAFAHTLLGMVHRRRGRLAEAEGFLREGLRLADRVGSGLPVHWDAACLLIDTLL
                     ARGRTAEARKIADRYRFGPPYPSAMVLPDGPCILGRLLLAEGRKEEAIAELEAAGAALE
                     PRERFNGIWAPWAGDLARALADDDPGRAAHLAARARVHAERFGTDTAIGESLRCMALFA
                     PPEEAERLLAEAVRHLERSSSAYEHALARVDYGIAIGSHRELARAQKQAMACGAEGLAA
                     RAQHARTSIRSSE"
     misc_feature    3348..3350
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     tRNA            5623..5696
                     /anticodon=(pos:18174..18176,aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="B083_RS0129900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Pro"
     gene            5623..5696
                     /locus_tag="B083_RS0129900"
     misc_feature    complement(6252..6267)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(6267..6280)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            6357..6560
                     /locus_tag="B083_RS0129905"
     CDS             6357..6560
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487268.1"
                     /locus_tag="B083_RS0129905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018487268.1"
                     /transl_table=11
                     /translation="MPEFRQPGWTRGIAPLDEGAGGQVFGGASPVAATPAVVATAGAVV
                     VAFAAGVAARHLANGGNVELPM"
     gene            6849..7022
                     /locus_tag="B083_RS1000000136530"
     CDS             6849..7022
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487269.1"
                     /locus_tag="B083_RS1000000136530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_165274052.1"
                     /transl_table=11
                     /translation="MSTASIPAVLSGTGALTESDRGRGPLDTVPVTSVTVTMTACVGIS
                     VCLTGSTIELPQ"
     gene            7096..7287
                     /locus_tag="B083_RS0129915"
     CDS             7096..7287
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965561.1"
                     /locus_tag="B083_RS0129915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028419786.1"
                     /transl_table=11
                     /translation="MNTSSTPAVLTATGALTESDPGATLPAIAPVTATPVVIVAALGAG
                     FVAGYAAGRAAGNVELPM"
     gene            7345..7545
                     /locus_tag="B083_RS0129920"
     CDS             7345..7545
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965562.1"
                     /locus_tag="B083_RS0129920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028419787.1"
                     /transl_table=11
                     /translation="MNMSPTPAALRGAGGLSESDPGRALPTLAPVAATPAVVAGVAVGV
                     ALVNAFVAGYNHCGGNVELPM"
     gene            8052..10004
                     /locus_tag="B083_RS0129925"
     CDS             8052..10004
                     /NRPS_PKS="Domain: Abhydrolase_1 (361-474). E-value:
                     4.3e-16. Score: 51.2. Matches aSDomain:
                     nrpspksdomains_B083_RS0129925_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378587.1"
                     /locus_tag="B083_RS0129925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_028419788.1"
                     /sec_met_domain="PF00561 (E-value: 9.5e-14, bitscore: 42.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 7.6e-11, bitscore:
                     33.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSRPTRPSGSSRLRPTLRAVLSALQGPVPLSREQAMGATERLAA
                     TTSLLSSVEHLARRREHRSSRMNEWAISRDAYARYNRPFRKLLDLASDERTHRALHAGR
                     VAASAALILPGNGRWRGAATLYLGVSGALLYPGERYGTDGSDQASTMVQTVTGLARLAP
                     SSRTQDALIWYVALQGNLSYLISGWVKLLGPDWRSGAALAGVMRTRTYGHEGVWKLAHR
                     HPRTTRALVYGVLGLECLFPVLYLRGGRLTRPVLGGAVLFHLANGYVMGLGRFLPAFAA
                     MHPMVAYTSTPRSHPAAAGRDDTMPAAVALLAAGGAAVLGTVAAARRLRVTDTPHGGTA
                     VTTRHGNELSVQGTLDGRSTDPVVVFVHGLGACPAYFAWIARAFGADRPWLMYNRAGYG
                     PSRRRADGEFTLEESVDDLVDLVEAAVPEGRQVALMGHSLGGEISRRAAVRLGSRVNSV
                     IYVDSSHPGQLTRSAQQGATAPRIGEGLRTMAISLRLGFGSLMRTPDPVANLPEQVRDK
                     VRMEFADSRVWTAAVREWKAVEQDFPSFTGPLDALDTHALVLSAQRTVDRDPDHLLMHK
                     DLADAHHGDRTVRSAVIEGADHDGILTDPQYAAATLRHLLAFLADTAAREPEARPGLPA
                     GTEPSGLTAASEENR"
     aSDomain        9135..9473
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0129925_Abhydrolase_1.1"
                     /evalue="4.30E-16"
                     /label="B083_RS0129925_Abhydrolase_1.1"
                     /locus_tag="B083_RS0129925"
                     /protein_end="474"
                     /protein_start="361"
                     /score="51.2"
                     /tool="antismash"
                     /translation="PVVVFVHGLGACPAYFAWIARAFGADRPWLMYNRAGYGPSRRRAD
                     GEFTLEESVDDLVDLVEAAVPEGRQVALMGHSLGGEISRRAAVRLGSRVNSVIYVDSSH
                     PGQLTRSAQ"
     gene            10001..10609
                     /locus_tag="B083_RS0129930"
     CDS             10001..10609
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965564.1"
                     /locus_tag="B083_RS0129930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028419789.1"
                     /sec_met_domain="cypI (E-value: 4.9e-36, bitscore: 115.0,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPRLPSATGSLLTRAFGGADGKVRLAAGVVFLGAICCQHPHPS
                     FDRVQRLDPLSSVFPNWRFFAPTPAQHDFQFYYRTLDVAGETSDWTALEVIQGRRPRQI
                     VWFPERRAEKAVYDLGSEILRVLDRGFEVAVTLPAFRILRSFFREEIERSGTPDVKGFQ
                     FALVQDSGYDKTEEPEIIFLSPYTPMRETAAPARESETV"
     gene            10606..11418
                     /locus_tag="B083_RS0129935"
     CDS             10606..11418
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487274.1"
                     /locus_tag="B083_RS0129935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_032756681.1"
                     /transl_table=11
                     /translation="MSTATPSGTSVATSPEVQDIGYGRVFADFYDRLLPHDGSAEQTAG
                     VLASWHPGGATLELGVGTGRVAVPLARLVGEVVGVDSSPEMLRRLCETVDATGAPVTPV
                     HGDIRTYADDSRYGLVYCVCATLSLVCDPAEQRTAVARAARQLAPGGTLVVETHNPGFV
                     TALHEGRARTSFFIPYAEPGAGVQTYSTLIPGGLWHASHLVHGGGRVSIGTEVTRLTTA
                     EDVDSYAADAGLVLVSRHGDWAGGPFLPEGSGVHISRYRRPASGEERS"
     gene            11415..13316
                     /locus_tag="B083_RS0129940"
     CDS             11415..13316
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378589.1"
                     /locus_tag="B083_RS0129940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_028419791.1"
                     /transl_table=11
                     /translation="MTATAAASGGAVRNLTRGQWRLLLGGTALGLLGVVCTLAQPVLLA
                     DLIRAAGDHRPVVGVVVALVVLFLLDAALSAAQGCLIGRAGENIVRDARVLLSGKVLRA
                     DRAHLDTRRQGDLHTRLVADTSLMKIALTQSLAQIVLNGLIVVGAVVMMAFTDIWLLLI
                     AVGCLAVAGTGSVWLARRLRRAALANREDIGDFGADLQRVLTALTTVKAANAEGREQSR
                     LAESADRARVSGNRVTVLNALFTPALNVGLQASLAAVMGIGMARVVSGSISLADFSAFA
                     MYLFYLVSPLVLVFLSIGTYLQGRAAVQRVDELDTLPQEDEHPSGDADAAAGRSGAPAD
                     EPSVRPAPQGGHPAVEFRDVSFGYGDRPVLEGVSFTVPAHGLTAVVGASGAGKTTVFQL
                     IERFYRPGGGAILLAGRDIAHLPTAEVRGRVGYVQQDNAAMRGTLRENIVYAAPDATEA
                     EIAEAVELAGLTEVVAELPDGLETLLGDQGTGLSGGQRQRLCVARALLQKPDVMLLDEA
                     TAHLDSDTEAVLRDSLRGIAERCAVVAIAHRISTVAEADRIVVLDEGRVRAVGTHTELL
                     RDDALYRRLAATQFADGPLGGRPAPDPVPDIAKSAQPGSDPVPEPVPAALPGPGAVR"
     gene            complement(13612..14625)
                     /locus_tag="B083_RS0129950"
     CDS             complement(13612..14625)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965568.1"
                     /locus_tag="B083_RS0129950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_028419792.1"
                     /transl_table=11
                     /translation="MGTYTMSPLGLSSTEERVYRFFLRNPGAAVGDARTAAPMDEEGVR
                     LAAARLRDRGLLHGSEARTWATDPGVVVARLAEEQLDAAYRTLRRLADPRPILRSLWRD
                     VPARSFAGGGGVYAGSAIALDRLEDLGQALARIDRAAFHADAEILAAIPNRALVPLNTA
                     HTLSLGLNCLRRGVRVRTLLESGAPAPGTGSEHLRQLRSHGAEVRVVEGLSELVLVYDR
                     RTALVPVDAHDIDRGVLCIEESGLVGSLVTLFEGLWATATDLVDLPPSKAGTGTLTGAQ
                     RTVLLLMCTTTKDETGARAAGMSLRTYRRHVSDLLALLGACSRAQAALLARERGWV"
     gene            14815..16668
                     /locus_tag="B083_RS0129955"
     CDS             14815..16668
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487277.1"
                     /locus_tag="B083_RS0129955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028419793.1"
                     /transl_table=11
                     /translation="MADAPAAAPPVQATPHSLREVVASRDLANLTGPLGSGKSRLVAGL
                     GSVSLLDLDRPGALERLPAALAEPTSAPLVVDSADGDHALAALEPLRLRPPGSGRPVLV
                     ISRRSLLARPGWADTGVAVMETGPWPDARIGRLATEARVTDARCRELIVRLAAGNPLIA
                     DAACRAVHAGAPPTAAGAVADGAAREIVERLSRERPTGPWQQALVRLATVWSADEELLD
                     AEPELFDTLAGLSPVVPTELGLALTEPFRGVIELAHRWRRPAAHRGTWARALAHRKKLL
                     ADEPAADRRSRLTEGIIALADDDAVRETMFPISVTRDVIHTATPDDADAIGTLMRQWAR
                     QGGLDTRWTDRLVERWLVDDPASFQLIRDGGDRIIGLTNTQQVTERTVNCVEPLLQQHT
                     DRLLDRPRGTGGWLLGAAYCPDRGAHAHLLRGLLRQVIMGGLLLTVSTPNPDYQRLLRG
                     LRFQRHGTTTDDVYRCGRKPEIFSQDFGSAALPDWTERLARASGVRRGPRPTGQEVARA
                     LAAIADPARLAESPLLLSPRTRTVAELRADLGEAVRRLADSEVQEEAEAGWILQHYYLG
                     RPRTHQRLAQQLHISRATYFRRLRYGLDRVGDGLAAERSVP"
     misc_feature    14935..14937
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16694..16963)
                     /locus_tag="B083_RS1000000137030"
     CDS             complement(16694..16963)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="B083_RS1000000137030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_232790490.1"
                     /transl_table=11
                     /translation="MGSDWSETAETLGALGHPVRLRLIQALAEGRTAVTELMELEGLGT
                     TGQIYHHLRQLVSAGWLETAGGGRYRIPPSRLVPLLVVVAGARR"
     gene            complement(17508..19100)
                     /locus_tag="B083_RS0129965"
     CDS             complement(17508..19100)
                     /NRPS_PKS="Domain: AMP-binding (10-416). E-value: 1.2e-113.
                     Score: 371.8. Matches aSDomain:
                     nrpspksdomains_B083_RS0129965_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487279.1"
                     /locus_tag="B083_RS0129965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_028419795.1"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-122, bitscore:
                     398.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSLASVLAESALRRPEHPAVVAGTRKITYRELWDEARRYAAAL
                     GARGIGPGDKVALLLPSTPHFPSAYFGVLALGGIAVPVHALLRADEIAYVLKDSGAAAL
                     ICAAPLLAEGGRAAETTGTPVLTVMAEEGGAEAEFAHAPRLDALAARTAPIGRQVARAP
                     EDIAVILYTSGTTGRPKGALLTHLNVVMNVDTTMLSPFDFTADDVLLGCLPLFHTFGQI
                     CGMNTCFRAGATLVLMPRFDGPGALDLMVRERCTVFMGVPTMYTALLEAARADPRRPAL
                     DRAFSGGAALPVAVLDAFRETFGCPVLEGYGLTETSPVVAYNQKAWPLRPGTVGRPIWG
                     VEVEIARAEVEDRIELLPAGETGEIVIRGHNVMAGYLNRPEATAEAIVDGWFRSGDLGV
                     KDDEGYLSVVDRKKDVVLRGGYNVYPREVEDVLARHPAIAQAAVVGLPHPVHGEEVCAV
                     VRPRPGTVPGPALGAEIVAWSKERMAPYKYPRCVEFVDAFPLGPSGKVLKRELVAQLTA
                     GARRLRTEAQEKT"
     aSDomain        complement(17853..19070)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0129965_AMP-binding.1"
                     /evalue="1.20E-113"
                     /label="B083_RS0129965_AMP-binding.1"
                     /locus_tag="B083_RS0129965"
                     /protein_end="416"
                     /protein_start="10"
                     /score="371.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ESALRRPEHPAVVAGTRKITYRELWDEARRYAAALGARGIGPGDK
                     VALLLPSTPHFPSAYFGVLALGGIAVPVHALLRADEIAYVLKDSGAAALICAAPLLAEG
                     GRAAETTGTPVLTVMAEEGGAEAEFAHAPRLDALAARTAPIGRQVARAPEDIAVILYTS
                     GTTGRPKGALLTHLNVVMNVDTTMLSPFDFTADDVLLGCLPLFHTFGQICGMNTCFRAG
                     ATLVLMPRFDGPGALDLMVRERCTVFMGVPTMYTALLEAARADPRRPALDRAFSGGAAL
                     PVAVLDAFRETFGCPVLEGYGLTETSPVVAYNQKAWPLRPGTVGRPIWGVEVEIARAEV
                     EDRIELLPAGETGEIVIRGHNVMAGYLNRPEATAEAIVDGWFRSGDLGVKDDEGYLSVV
                     DRKKDVV"
     CDS_motif       complement(17943..18029)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0129965_0002"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="B083_RS0129965"
                     /protein_end="386"
                     /protein_start="357"
                     /score="36.6"
                     /tool="antismash"
                     /translation="PAGETGEIVIRGHNVMAGYLNRPEATAEA"
     CDS_motif       complement(18543..18602)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0129965_0001"
                     /evalue="5.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="B083_RS0129965"
                     /protein_end="186"
                     /protein_start="166"
                     /score="25.1"
                     /tool="antismash"
                     /translation="AVILYTSGTTGRPKGALLTH"
     misc_feature    19096..19111
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            complement(19108..20652)
                     /locus_tag="B083_RS0129970"
     CDS             complement(19108..20652)
                     /NRPS_PKS="Domain: AMP-binding (15-418). E-value: 1.7e-71.
                     Score: 232.9. Matches aSDomain:
                     nrpspksdomains_B083_RS0129970_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487280.1"
                     /locus_tag="B083_RS0129970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_028419796.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-69, bitscore:
                     225.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSNETYVSQILQVISAEPEKVVLSWRGRTLTAAELTTLVRSAAR
                     TLHQHAGGTDGGAVVAILTVTNTAPTLVLRYAANLAGATVVHLHTTNAVDPADHLAADA
                     RLKVLRETGATYLAVDAENLASARELRERLGTPLTLASLDDLGPDVLDLTAGDPDALDP
                     DTVAIPPDRPAVVTYTSGTTGEPKGIAFDFRARNGFISAGLQMGWRSVYLACLPLSHSS
                     GATADDSLASGGSVVLRDGFDPGDVLHRIERHGITRMLLSPPQLYLLMDHPEVDSTDLS
                     SLTMVTYVGCPASPERLGEAVKVFGDVLIQVYATSEAGFVSMLSPAEHLDPRLRVTVGR
                     PMPGWVRITDPEDHRDLPPGETGEVCVRSPFTMSAYVAEPELTARTVRDGWVHTGDLGF
                     VDGDGYLHLRGRIGEVVKTNGIKIHPVTVENAFLAHPDVVQAAVFCVRDRDRVEHLHAA
                     VVLREAAAATPDTLAEHIRAAISPKHVPARIHIRPALPLTGVGKPDKARLAAEASG"
     aSDomain        complement(19399..20607)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0129970_AMP-binding.1"
                     /evalue="1.70E-71"
                     /label="B083_RS0129970_AMP-binding.1"
                     /locus_tag="B083_RS0129970"
                     /protein_end="418"
                     /protein_start="15"
                     /score="232.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="SAEPEKVVLSWRGRTLTAAELTTLVRSAARTLHQHAGGTDGGAVV
                     AILTVTNTAPTLVLRYAANLAGATVVHLHTTNAVDPADHLAADARLKVLRETGATYLAV
                     DAENLASARELRERLGTPLTLASLDDLGPDVLDLTAGDPDALDPDTVAIPPDRPAVVTY
                     TSGTTGEPKGIAFDFRARNGFISAGLQMGWRSVYLACLPLSHSSGATADDSLASGGSVV
                     LRDGFDPGDVLHRIERHGITRMLLSPPQLYLLMDHPEVDSTDLSSLTMVTYVGCPASPE
                     RLGEAVKVFGDVLIQVYATSEAGFVSMLSPAEHLDPRLRVTVGRPMPGWVRITDPEDHR
                     DLPPGETGEVCVRSPFTMSAYVAEPELTARTVRDGWVHTGDLGFVDGDGYLHLRGRIGE
                     VVKT"
     CDS_motif       complement(19498..19581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0129970_0002"
                     /evalue="3.70E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="B083_RS0129970"
                     /protein_end="385"
                     /protein_start="357"
                     /score="16.1"
                     /tool="antismash"
                     /translation="PPGETGEVCVRSPFTMSAYVAEPELTAR"
     CDS_motif       complement(20083..20133)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0129970_0001"
                     /evalue="1.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="B083_RS0129970"
                     /protein_end="190"
                     /protein_start="173"
                     /score="21.0"
                     /tool="antismash"
                     /translation="AVVTYTSGTTGEPKGIA"
     gene            20863..22107
                     /gene="hemA"
                     /locus_tag="B083_RS0129975"
     CDS             20863..22107
                     /EC_number="2.3.1.37"
                     /GO_function="GO:0003870 - 5-aminolevulinate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006783 - heme biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (49-391). E-value:
                     2.5e-72. Score: 235.9. Matches aSDomain:
                     nrpspksdomains_B083_RS0129975_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="hemA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566618.1"
                     /locus_tag="B083_RS0129975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="5-aminolevulinate synthase"
                     /protein_id="WP_028419797.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-72, bitscore:
                     236.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.1e-07,
                     bitscore: 21.4, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 6.9e-08, bitscore:
                     22.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHYLELFSRNMGEGGAPDAKREFLELGRLAGKFPAARSLRDGVT
                     SEISVWCSNDYLGMGQHPLVLAATREALDEYGAGSGGSRNIAGTNHYHVLLEKELADLH
                     GKADALLFTSGYTANDGALTVLAGLPEKCVVFSDEMNHASIIDGLRHSGAEKRIFRHND
                     TAHLEELISATDPDRPKMIVMESVYSMGGDVAPLAEIARIAREHGAMTFLDEVHAVGMY
                     GPEGAGIAAGLGIADEFTVIMGTLAKGFGTTGGYIAGPAELVDAVRGLSRPFIFTTALP
                     PAVAAGALAAVRHLRTSEEERDRLRENARLTHRLLRERAIPFLSDGSHIVSIFVGDDAL
                     ARRISALLLARHGIYVQAVNAPSVRVGQEILRSAPGAVHEPADIEGFVTALDDIWRELG
                     VTRAQGPHMPSGTDG"
     aSDomain        21010..22035
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0129975_Aminotran_1_2.1"
                     /evalue="2.50E-72"
                     /label="B083_RS0129975_Aminotran_1_2.1"
                     /locus_tag="B083_RS0129975"
                     /protein_end="391"
                     /protein_start="49"
                     /score="235.9"
                     /tool="antismash"
                     /translation="VWCSNDYLGMGQHPLVLAATREALDEYGAGSGGSRNIAGTNHYHV
                     LLEKELADLHGKADALLFTSGYTANDGALTVLAGLPEKCVVFSDEMNHASIIDGLRHSG
                     AEKRIFRHNDTAHLEELISATDPDRPKMIVMESVYSMGGDVAPLAEIARIAREHGAMTF
                     LDEVHAVGMYGPEGAGIAAGLGIADEFTVIMGTLAKGFGTTGGYIAGPAELVDAVRGLS
                     RPFIFTTALPPAVAAGALAAVRHLRTSEEERDRLRENARLTHRLLRERAIPFLSDGSHI
                     VSIFVGDDALARRISALLLARHGIYVQAVNAPSVRVGQEILRSAPGAVHEPADIEGFVT
                     AL"
     gene            22534..>26868
                     /locus_tag="B083_RS01000000134275"
     CDS             22534..>26868
                     /NRPS_PKS="Domain: PKS_AT (111-410). E-value: 1.5e-101.
                     Score: 331.6. Matches aSDomain:
                     nrpspksdomains_B083_RS01000000134275_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (495-563). E-value: 4.3e-25. Score:
                     79.8. Matches aSDomain:
                     nrpspksdomains_B083_RS01000000134275_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (594-1019). E-value:
                     1.9e-176. Score: 579.1. Matches aSDomain:
                     nrpspksdomains_B083_RS01000000134275_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1126-1420). E-value: 5.5e-102.
                     Score: 333.1. Matches aSDomain:
                     nrpspksdomains_B083_RS01000000134275_PKS_AT.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140390.1"
                     /locus_tag="B083_RS01000000134275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_032756684.1"
                     /sec_met_domain="PP-binding (E-value: 7.9e-13, bitscore:
                     39.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 7.2e-220, bitscore:
                     721.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.3e-89, bitscore:
                     289.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.6e-102, bitscore:
                     333.1, seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLLAAKESENTMAHPDGTEAPLLWTLAGNGRQALAAGARGLHTY
                     LAGHDDWSPQDIALTLARTASEGSRRAALVADGRDGFLRRLDALADGRSTPGLLEGPAG
                     VGGRVAFVFPGQGAQWPRMAVDLLDTSPVFRDRMDACAQALEPFVDWSPLDVLRAPDAP
                     GAPAGDRADVVQPLLFAVTVSLTALWRSHGVEPAAVLGHSVGEVTAAAVSGALSLDDSA
                     RVVALWSQAQATLAGQGDMVSVMAPADEVEPRLRRWEGRLVVAAHNGPRSVIVSGDRDA
                     AAELLDALAADAVHARRIAVGLAAHSPHIDAIIPRMRADLAPIRPRTPRLPYYSGLTGG
                     RLDAPVLDADYWCRNLRNTVRFHQAAGALLRDGHGVLLEVSPHTVLTSALTDCVEEQGA
                     EAAVLGTLRRDQGGPGRFLTSLGDLYVRGVPAHREAPSAVEHARVRELPTAVLTALADT
                     GPADVNGTDGTDGEEGGAAFRAELAAMDVRERRAALARLVGEEIAALTGRSDPVPAELA
                     FLDLGFDSVTAVELRNRLGAATALRIPATVVFDCPTPAALTAYLSTAIGGDRSGTDAAT
                     DTNAVTAVPVRRPVDDDPVVIVGMGCRYPGGVGSPDELWELVSSGADAVSALPADRGWD
                     TAGRYDPAPGTPGRYYQREAGSLAGAAEFDAEFFGISPREAAAMDPQQRLLLETAWEVL
                     ERAGIDPVTLRRTPTGVYVGAMTMDYGPSLEQGADEGGHLLTGNTGSVASGRLAYTLGL
                     EGAAVTVDTACSSSLVALHLAVRALRSGECSLALAGGATVMSTVGMLVEFSRQGGLAPD
                     GRCKAFAAAADGFGLAEGVGMLLLERLSDARRNGHPVLAVIRGSAVNQDGASNGLTAPS
                     GPSQQRVIRAALADAGLAASDVDVVEAHGTGTRLGDPIEAQALLATYGQDRPGDRPVWI
                     GSLKSNIGHTQAAAGVGGVIKSVLAMRHGVMPRTLHVDGPTPEVDWAAGAGQLLTEART
                     WDDTGRPRRAGVSSFGISGTNAHVILEAAPAEAPATVVESAPRSGAVVWPVSARSAEAL
                     RAQAGALAARVAAEPALDAVDVGYSLAVGRASFEHRAAVVGGDRSELLRGVRALAEGRS
                     AQVPGLVRGGGVSSGRSVLVFPGQGSQWVGMAAELAAESGVFAGRMGECERALSPYVDW
                     SLTEVLGSERLLARVDVVQPVLWAVMVSLAEVWRSFGVVVDGVVGHSQGEVAAACVAGG
                     LSLEDGARVVALRSRAVGVLAGRGGMASIPLPVDVVRERLVGWSGRLSVAAVNGPSSTV
                     VSGDADAVAGLLEVLAGEGVRARRVEVDYASHSSHVEAIREQLLVGLKDITPRTGSVPF
                     YSSVTGGLLDTKGLDAEYWYRNLRETVEFGKATEALLGEGFRFFVEASPHPVLGVAVGE
                     SVEAAGVDAAALGTLRRGEGGQEQVLRAVGRAWERGLDVDWSG"
     CDS_motif       22864..22917
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0001"
                     /evalue="7.00E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="128"
                     /protein_start="110"
                     /score="24.4"
                     /tool="antismash"
                     /translation="FVFPGQGAQWPRMAVDLL"
     aSDomain        22867..23763
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS01000000134275_PKS_AT.1"
                     /evalue="1.50E-101"
                     /label="B083_RS01000000134275_PKS_AT.1"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="410"
                     /protein_start="111"
                     /score="331.6"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Isobutyryl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGAQWPRMAVDLLDTSPVFRDRMDACAQALEPFVDWSPLDV
                     LRAPDAPGAPAGDRADVVQPLLFAVTVSLTALWRSHGVEPAAVLGHSVGEVTAAAVSGA
                     LSLDDSARVVALWSQAQATLAGQGDMVSVMAPADEVEPRLRRWEGRLVVAAHNGPRSVI
                     VSGDRDAAAELLDALAADAVHARRIAVGLAAHSPHIDAIIPRMRADLAPIRPRTPRLPY
                     YSGLTGGRLDAPVLDADYWCRNLRNTVRFHQAAGALLRDGHGVLLEVSPHTVLTSALTD
                     CVEEQGAEAAVLGTLRRD"
     aSModule        22867..24222
                     /complete
                     /domains="nrpspksdomains_B083_RS01000000134275_PKS_AT.1"
                     /domains="nrpspksdomains_B083_RS01000000134275_ACP.1"
                     /locus_tags="B083_RS01000000134275"
                     /monomer_pairings="mmal -> Me-mal"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       23038..23106
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0002"
                     /evalue="3.50E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="191"
                     /protein_start="168"
                     /score="28.9"
                     /tool="antismash"
                     /translation="DRADVVQPLLFAVTVSLTALWRS"
     CDS_motif       23110..23214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0003"
                     /evalue="8.70E-15"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="227"
                     /protein_start="192"
                     /score="46.8"
                     /tool="antismash"
                     /translation="GVEPAAVLGHSVGEVTAAAVSGALSLDDSARVVAL"
     CDS_motif       23326..23364
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0004"
                     /evalue="2.10E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="277"
                     /protein_start="264"
                     /score="11.4"
                     /tool="antismash"
                     /translation="AAHNGPRSVIVSG"
     CDS_motif       23440..23466
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0005"
                     /evalue="8.90E-01"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="311"
                     /protein_start="302"
                     /score="3.3"
                     /tool="antismash"
                     /translation="LAAHSPHID"
     CDS_motif       23572..23619
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0006"
                     /evalue="5.80E-06"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="362"
                     /protein_start="346"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LDADYWCRNLRNTVRF"
     CDS_motif       23665..23691
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0007"
                     /evalue="1.60E-01"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="386"
                     /protein_start="377"
                     /score="5.4"
                     /tool="antismash"
                     /translation="LEVSPHTVL"
     aSDomain        24019..24222
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS01000000134275_ACP.1"
                     /evalue="4.30E-25"
                     /label="B083_RS01000000134275_ACP.1"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="563"
                     /protein_start="495"
                     /score="79.8"
                     /tool="antismash"
                     /translation="RLVGEEIAALTGRSDPVPAELAFLDLGFDSVTAVELRNRLGAATA
                     LRIPATVVFDCPTPAALTAYLST"
     aSDomain        24316..25590
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS01000000134275_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.90E-176"
                     /label="B083_RS01000000134275_PKS_KS.1"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1019"
                     /protein_start="594"
                     /score="579.1"
                     /tool="antismash"
                     /translation="VVIVGMGCRYPGGVGSPDELWELVSSGADAVSALPADRGWDTAGR
                     YDPAPGTPGRYYQREAGSLAGAAEFDAEFFGISPREAAAMDPQQRLLLETAWEVLERAG
                     IDPVTLRRTPTGVYVGAMTMDYGPSLEQGADEGGHLLTGNTGSVASGRLAYTLGLEGAA
                     VTVDTACSSSLVALHLAVRALRSGECSLALAGGATVMSTVGMLVEFSRQGGLAPDGRCK
                     AFAAAADGFGLAEGVGMLLLERLSDARRNGHPVLAVIRGSAVNQDGASNGLTAPSGPSQ
                     QRVIRAALADAGLAASDVDVVEAHGTGTRLGDPIEAQALLATYGQDRPGDRPVWIGSLK
                     SNIGHTQAAAGVGGVIKSVLAMRHGVMPRTLHVDGPTPEVDWAAGAGQLLTEARTWDDT
                     GRPRRAGVSSFGISGTNAHVILEAAP"
     aSModule        24316..26793
                     /domains="nrpspksdomains_B083_RS01000000134275_PKS_KS.1"
                     /domains="nrpspksdomains_B083_RS01000000134275_PKS_AT.2"
                     /incomplete
                     /locus_tags="B083_RS01000000134275"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       24796..24843
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0008"
                     /evalue="1.30E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="770"
                     /protein_start="754"
                     /score="17.4"
                     /tool="antismash"
                     /translation="GAAVTVDTACSSSLVA"
     CDS_motif       25219..25263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0009"
                     /evalue="2.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="910"
                     /protein_start="895"
                     /score="13.2"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       25324..25368
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0010"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="945"
                     /protein_start="930"
                     /score="11.0"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     CDS_motif       25906..25959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0011"
                     /evalue="1.50E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1142"
                     /protein_start="1124"
                     /score="26.5"
                     /tool="antismash"
                     /translation="VLVFPGQGSQWVGMAAEL"
     aSDomain        25912..26793
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS01000000134275_PKS_AT.2"
                     /evalue="5.50E-102"
                     /label="B083_RS01000000134275_PKS_AT.2"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1420"
                     /protein_start="1126"
                     /score="333.1"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWVGMAAELAAESGVFAGRMGECERALSPYVDWSLTEV
                     LGSERLLARVDVVQPVLWAVMVSLAEVWRSFGVVVDGVVGHSQGEVAAACVAGGLSLED
                     GARVVALRSRAVGVLAGRGGMASIPLPVDVVRERLVGWSGRLSVAAVNGPSSTVVSGDA
                     DAVAGLLEVLAGEGVRARRVEVDYASHSSHVEAIREQLLVGLKDITPRTGSVPFYSSVT
                     GGLLDTKGLDAEYWYRNLRETVEFGKATEALLGEGFRFFVEASPHPVLGVAVGESVEAA
                     GVDAAALGTLRRG"
     CDS_motif       26068..26136
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0012"
                     /evalue="1.80E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1201"
                     /protein_start="1178"
                     /score="29.8"
                     /tool="antismash"
                     /translation="ARVDVVQPVLWAVMVSLAEVWRS"
     CDS_motif       26140..26250
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0013"
                     /evalue="9.80E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1239"
                     /protein_start="1202"
                     /score="49.7"
                     /tool="antismash"
                     /translation="GVVVDGVVGHSQGEVAAACVAGGLSLEDGARVVALRS"
     CDS_motif       26356..26394
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0014"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1287"
                     /protein_start="1274"
                     /score="14.5"
                     /tool="antismash"
                     /translation="AAVNGPSSTVVSG"
     CDS_motif       26398..26457
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0015"
                     /evalue="2.90E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1308"
                     /protein_start="1288"
                     /score="-2.0"
                     /tool="antismash"
                     /translation="ADAVAGLLEVLAGEGVRARR"
     CDS_motif       26464..26496
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0016"
                     /evalue="1.00E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1321"
                     /protein_start="1310"
                     /score="11.9"
                     /tool="antismash"
                     /translation="VDYASHSSHVE"
     CDS_motif       26602..26649
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0017"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1372"
                     /protein_start="1356"
                     /score="16.9"
                     /tool="antismash"
                     /translation="LDAEYWYRNLRETVEF"
     CDS_motif       26692..26721
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0018"
                     /evalue="1.60E-02"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1396"
                     /protein_start="1386"
                     /score="8.2"
                     /tool="antismash"
                     /translation="FVEASPHPVL"
     CDS_motif       26704..26760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS01000000134275_0019"
                     /evalue="6.50E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="B083_RS01000000134275"
                     /protein_end="1409"
                     /protein_start="1390"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="SPHPVLGVAVGESVEAAGV"
ORIGIN
        1 cccagcaccc ggtggacccg cagttcgtgg cggccccggg ccaccgtcac gctctccacc
       61 cggaggccgg ggacggtgga ggggccggac gggaacacgg ggacgtgcca ggacccggcc
      121 cagccccagc cctcgccatg tccggccccg agcggacgga tacggcgccg ggtgctgcgt
      181 accccctcga ccaccaccga caggtggttg tccgccgggt tcgccgccga ggtcggcccg
      241 gtcacggtgg agtaggcgag ccgggcgtag tgcgggtccg tgccggccgc cgactcgccc
      301 tcgtcggggc ggacgtggtc gctgccgtgg ttgtgcagcc gcacgacccc gtcggcgcgc
      361 gtcgactgca cgaggaaccc cggtgcccgg acggagagca cccggtccgg tccctcgctc
      421 ggcgccgcct cctccaccga cgcccacagg ggatgcccgg cgggggccag cagcgcgacg
      481 aacgccttcg acgcccaata gggcgacgcg ggacccgaat aggactgcag ggtcgccgga
      541 tgggggccgt gccagccgag gctcagcagc ccgtcctccg cggccgcccc gcgctccagg
      601 aagtaccgca gcgatccgtt gaccagccgg cgcgaggccc cgggggcgag cggggtgtgc
      661 ccggtcacgg cgcccagccc caccgccgcg gccgcggcga accggtaggt cagggagcgc
      721 ccgaagtgca gcggggcccc gtcgccgccg aacatcagcg agaagctctc cagatgctca
      781 cgcagccgcg ccccgtggga cgtcggggcc tgcccgtcgc ccgccagcag gccgtcgagc
      841 accggataca ggtgcagggc ccagccgttg tagtggtcga aggcgcgccc gtccccgtcg
      901 gcgtaccagc cgtcgccccg gtaccagccc tccagcagct ccagcgcccg ctcccgcgcg
      961 cgggccgtct ccgcgtcgcc ccgccccacc gactccagga agccggcgac ggtgtacggg
     1021 aagaggtacc agttgttgcc tgccgggagg tgccgcagcg cgccccgcag ccactgctcg
     1081 gcccggtccc ggaccccggg ctccagccgg tcccagagcc agggccgggt cagccgcagc
     1141 ccgagcgcga cggaggccga ttccaccatg ggctgcccct gcacatggtg gtccaggacg
     1201 acgggccagg actccgcgtc ctcccgcccc ggcgtacggg tgccggccgc caggccccgc
     1261 gcgtaccgat ccagccattc gtgcgggtcc ctccccccgg ccccggcgac ccggaaggcg
     1321 gccgcgagga aggtccgcgc atacccttcg agcccgtcgg agcgcacccc ggaacgggac
     1381 ggaggccccg gcaggtcgag cagtgccccg ccgggggtgg cccaccgcca ggcggcgtgc
     1441 agcagcccgt cggcggcggc ctcccagtgc gctcgggtgt acccggtgta cgggctcgac
     1501 gcccggtcct ccggaggaag tccgaagggg agcgggcggg agcggaaggt cgtcatgggg
     1561 gaaggccggg cccttcgtgg tggaccggtg gaccggtgga cacggaagcc ggcctggcga
     1621 tggacgcggg tcacggtcgg cacagggaag cctgatcgag tgatcggaaa cggtcaagag
     1681 attcaacgga atccaccaga aatgatcaaa cgatcacatc gcccggaagg agcccggtgc
     1741 ctccccgcca gagcccgccg ctcagggaag cagcagccag tccgccccga ccgccgccac
     1801 cagaccggcc ccgagcagcc agctgcccag ccgggtgcgg ccgttccggc tcagctcgat
     1861 gaccacaccg cacaggatga gtgcgagccc gtacaccccg acgaccagca ccgacgaccg
     1921 gctcgcgatc cgcagggcga ggaccacgcc catggcgatc atgccgacgg aggagaggac
     1981 gatccgcagc cgccgcgcct gacgcggggt cagcctccgc tcgccgtcaa cctcgccgtc
     2041 ccggtcgtcg cctgcgatct ccgcgccgtc ggcggaatcc gcgccgtcag gcgcgtccgc
     2101 cccgttgcgg gtggcgtcgg tacgggtgtc gcccgcggtg tcctcgggcg cctgcgccgt
     2161 cgtgccctcg gctatcgggg tgtcggtgcc ccggtcccgt ccctcgcgcc gggtccggac
     2221 ccggtcctgg tcagaagtgc tcatggggcc ggatcgtaac ggctgcgcgg cggccccgtt
     2281 cccggaccgc cgggttccgc cgccgcccgc tccgagcctg cgggccgcct accccagcaa
     2341 tcgcggagcc tcggcctccg catcgaccgg acgccccgcc tccacccggt cggccaactc
     2401 gtgcgcccag tccaccagtc cgccgccccg gatcccgtac ggccacgccc caccgtacga
     2461 ggagagcgcc ccggcgcccc ggcgcagcag ccgcgcgcct cccgcccggt tgccacgcgc
     2521 tccgtgcgtc agtcccacgg ccagctgcgc gagcccgcgc cacagctcgc gttcggcccg
     2581 cggccccgac ttccaggcgt cctcgaacac ctcgtgggca tggaacggca tccccgcgtc
     2641 cagcagccgc tgcgcctccc ggagcgtctc gtccggcgta cggacgacgc cctcgggctg
     2701 ccgctcgacg ccggggctcc cgtacggcag ggggcgcccc agtccgtccc gggggcgcgc
     2761 gttgcgcgcc cggccctcgg tgtcacggtc cctgctcgtc tcgtccacta cccgattgtg
     2821 cctcgtacct gcagggaatc ggccgaaccc tgtcgatggg cacccgcgca cgactaggct
     2881 cgaccgtcgt cactgcatgc catgtgggaa gggtgggcat gaagccgtcc cggccgttgt
     2941 acgaacgtga accggaactc gccgctgccg cgagggcggt ggacgacctg tgcggagcgc
     3001 aggccgtcgg cgggctcctg gtcttcagcg gggaggcggg gctcggcaag accgccctgc
     3061 tcgcggagat ccggacgatg gccgccgacc gctgcacgat ctggtccgcc cggggcggcg
     3121 agaccgtcac gtccgtgccg ttccacgtcg tacggcagtt gctgcagccc gcactcgacc
     3181 agttcccgcc cgacgagacc cgggcgctct tcggtgactg gtacgacacc accgcgcccg
     3241 ctctcgggct ggccgagccc agcggcccgc agcccgaccc gcagggtgtc cgtgacggcc
     3301 tcgacttcgt cgtcgcccgg ctcgcctcgc gcctcagcca ccggccgtta ctgcttctgg
     3361 tggacgacgc ccactgggcg gacggcgaat ccctcacctg gctctcctcg ttcacggccc
     3421 ggctcggtga actcccgctg ctcgtcgtcc agtcgtaccg gccgcaggag atggccgagc
     3481 gcaacgcgag ttacgtggcc gaccgcgcgg ccgagcgcga cgcggagggg gacagcaacg
     3541 tcacccgggt cgccctgcgg gcgctgaccc cggacgccac cgccgagctg gcccgcgccg
     3601 ccctgggcga acacgccgac gacccgttct gccgcgaggt gtgggcggtc accggcggca
     3661 acccgtacga ggcggtcgag ctggtcgcca aggtgcagga ccaggagctg gcaccggtcg
     3721 aggagtcggc cgggcagctg cgggagctgg gcgcctccgc ccggggcagc gggctcgtcg
     3781 cccgactgga gcggctcggt accaacgcca accggttcgc ctgggccgcc gccgtgctcg
     3841 gtaccgacat ctcccaggaa ctggccgcca ccctcgccgg gatgagttcg gcggaggccg
     3901 ccgactgcac ggcccggctg cgcgacgccc gtatcgtcag cggcttcgac ccgctggagt
     3961 tcgtccaccc gctgatcgcg accgccgtct accgctccat cccgcccgcc acccgcaccg
     4021 cgatgcacgg ccgcgccgcc tgggccatca cccgggccgg cctcggcgcc gcggcggcct
     4081 cccggcacct gctggaggtc caccccgacg acgaccagga actggtcgcc cagctccgcg
     4141 aagccgccgg ccagcacctc gccgtcggcg ccccggaagc ggccaggcgc tgtctggaac
     4201 gggccctgga ggagccgccc cgcccgaagg accgcgcggt gctgctgtac gaactgggct
     4261 gcgccaccct gctcagctcc ccgcccacca ccgtgcagca cctgcgcgcc gccctggaca
     4321 tgcccggcct cgacgacggc ctgcgggtcg acgcgacgtt ccggctcgcc gccgcgctcg
     4381 cccacaacaa ccagctcaag gacgccgcgc tcgccctcgc cgccgaagcg gcccgtacgg
     4441 caccgggccc cggcctgatg cgactgcagg ccgcgcactt catgtgggag ggcatgcagg
     4501 ccgccgagga cgacggtccg gcccgctccc gccgcctcac ccgcaacgcc gaccacctca
     4561 agggccgcga caacgccgag cgggcgctgc tcaccctgcg cgccttcgac gccatgctgc
     4621 gcggcgagaa cgcccagctc atcgtcgacc tctgcgaacg cgccctggtc gacggcagcc
     4681 cggcccgcgg cctcggctgg accgactccg agtggggctt cgaactcccc accatggtcg
     4741 ggatcaccta cgccttcacc gaccagctcg accgggccga cagcctcttc ggcgaagccg
     4801 tgcgggcctt cgagatctcc ggctggagcg gggcccacct ggccttcgcg cacaccctgc
     4861 tcggcatggt gcaccgccgt cgcggccgcc tcgcggaggc cgagggcttc ctgcgcgagg
     4921 ggctccgcct ggccgaccgc gtcggctccg gcctgcccgt ccactgggac gcggcatgcc
     4981 tgctcatcga cacactgctg gcccggggcc gtacggcgga ggcccgcaag atcgccgacc
     5041 gctaccgctt cggcccgccc taccccagcg ccatggtcct gccggacggc ccctgcatcc
     5101 tgggccgcct gctgctggcc gagggccgca aggaggaggc gatcgcggaa ctggaggcgg
     5161 cgggtgccgc cctggagccg cgcgagcggt tcaacggcat ctgggcaccc tgggccggcg
     5221 acctcgcccg cgccctggcc gacgacgacc ccgggcgcgc cgcccacctc gcggcccggg
     5281 cccgggtgca cgccgaacgg ttcggtacgg acaccgccat cggcgaatcc ctgcgctgca
     5341 tggccctctt cgcaccgccg gaggaggccg agcgactcct cgcggaggcc gtccgccacc
     5401 tggagaggtc ctcctccgcc tacgaacacg cactggcgcg tgtcgactac ggcatcgcga
     5461 tcggctccca ccgggaactg gcccgggccc agaagcaggc catggcctgc ggcgccgagg
     5521 gactggcggc ccgcgcccag cacgcacgga cgtcgatccg gtcctcggag tgaggtaatg
     5581 tttgtcctgc gcggccaccc ggaccaccgg gaggaaccgc agcgggacgt ggcgcagctt
     5641 ggtagcgcac ttgactgggg gtcaaggggt cgcaggttca aatcctgtcg tcccgactgg
     5701 agacagtcgc agatcagggc cggtttcgga gcaatccgag accggccctt gatcattttc
     5761 ggggaccagg tggggaccgg tcgggaccgg tcgggaccgg tcggagctcc cggcgtccgg
     5821 gcgtgccgtc gcgaacgcct cgttgaccgg gcggggagac atccgtcgga cctcctcggg
     5881 cccccgcagg ccgtggtgcc ggtcgcgccg gagtgcgcag cgccttaatc agacccggtg
     5941 cgcgttcggc ggagaggccg acgacggcgc cggtgccggt acgggcggcg gactccctga
     6001 tccatagccc ggcggcgatc tcggagagtg cggggtgccc gcgccgtcgc gccggtgacg
     6061 ccgtcgcgcg tcgggacgga gggagcccgc ggagccggtc ggcctctctc aacgcctcgc
     6121 gttccaggcc ggatcgacgg agagggtacg cgccgcatac ccccgtgccc gaacccgcag
     6181 gatgctgctg cggagtccgc atcctcatgc cagcggagtt gtcttccctt tccgtcgggc
     6241 tctcggcatc gtgtggagcg catcacagaa cgtctgttca cgcgggggcc ggctcccggg
     6301 tgcgctcgcg cgcgcctgga cgggccccgg tgacggccca cccatgaagg agagacatgc
     6361 ccgaattcag acaacccggt tggaccaggg gcatcgcccc gctcgacgaa ggcgccggcg
     6421 gtcaggtgtt cgggggcgcg tccccggtcg ccgcgacccc ggcggtcgtg gccaccgcgg
     6481 gcgccgtggt cgtcgccttc gcggccggtg tggccgcccg ccatctcgcc aatggcggca
     6541 acgtcgagct gccgatgtag gtggcggcac cccgccaccc gtatccgccg gggaagacgc
     6601 ccggcgcgcg gcccggacac ccgccgctcc caccggggcg gcccgtcccg accccttcct
     6661 gtcggaaccg tgtcccgtca ggggccgccc gcgtcggtcg ccgcacccat gacggctcga
     6721 cgacgggaag tccgtccatc ggccgggcac gcggtcgacg gcacccggcg ccgcgacctg
     6781 cggatgcatc ctcccggtgc cactcgcccg tgacatccac cctgccgccc accagcgagg
     6841 agaagtcctt gagtactgct tcgataccgg ccgtcctgtc cgggaccggt gccctgaccg
     6901 agtccgaccg cggccggggg ccgctcgaca ccgttccggt cacctccgtc acggtcacca
     6961 tgacggcctg cgtcggcatc tcggtctgcc tcaccggcag caccatcgaa ctcccgcagt
     7021 aggcccgacg ggccgcccgt cgcgggtggc ccctgctcct cagccctacc cacacctcac
     7081 cagtaggaga gtcccatgaa cacgtcctcg actccggccg tcctgaccgc gaccggtgcc
     7141 ctgaccgagt ccgatcccgg tgcgacgctg ccggccatcg cgccggtcac tgcgactccg
     7201 gtggtcatcg tcgccgccct gggagccggg ttcgtcgccg gctacgcggc cggccgcgcg
     7261 gccggcaacg tcgaactccc catgtagtcg cggttcccgc gacaccggac cgttccgttc
     7321 catcactcca gtgaggagaa ccccgtgaac atgtctccga caccggccgc cctgcgcggc
     7381 gccggtggtc tgtccgagtc cgaccccggc cgggcgttgc cgaccctcgc gccggtcgcc
     7441 gcgacccccg cggtcgtggc cggcgtggcc gtcggcgtcg ccctggtgaa cgccttcgtc
     7501 gccggttaca accactgcgg cggcaacgtc gagctgccga tgtgagccca tcacaccgtc
     7561 cccgtcgccg cccccggtgg gggaacgcag tgaacacggc gacgtaccgg gggacggtgg
     7621 gccgccccgg cggcacgggc gccgagcggt aggcccgtcg cccccggccc cggcacgggg
     7681 agccgcggcc accgtgccgg ggccggccgg gagcgacggt gcgtcggtga cgggaggacg
     7741 agcgcctcca gggcggtcgc ccgcccgtgc caccaccacg cccgcactca cggcccggcc
     7801 ccggcacgaa cggaccccgc ccggcccggg tccccggccc ggcaggaacg tcccgcacga
     7861 tccgataccc cccggacagc gttccgcacg atccgatccc cccgggacag cgtcccgcac
     7921 gacccgatcc cctggacagc gttccgcccg gcccgtagga cccggtaccg gctccagagc
     7981 tgcccgccac cctccgcctc gtcaccccga cgccccccgc ctccttcgtc cccagcacgg
     8041 aaggcctgtc catgccctca cgccccacca gaccgagtgg atccagcagg ctgcggccga
     8101 cgctgcgcgc ggtcctgtcc gccctgcaag gccccgtccc gctctcccgc gagcaagcca
     8161 tgggcgccac cgagcggctg gcggccacga cgtccctgct gtccagcgtc gagcacctcg
     8221 cgcgccgccg ggagcaccgg tcgagccgga tgaacgaatg ggccatctcc cgcgacgcgt
     8281 acgcccgtta caacaggccc ttccgcaaac tgctcgacct ggcctccgac gagcggaccc
     8341 accgggcgct gcacgccggg cgggtggccg cgagcgcggc tctcatactg cccggcaacg
     8401 ggcggtggcg cggggccgcc accctctacc tcggcgtcag cggagcgttg ctctacccgg
     8461 gcgagcgcta cggcaccgac ggctccgacc aggcgtccac catggtgcag accgtcaccg
     8521 ggctggccag actcgccccc tcatcccgca cccaggacgc cctgatctgg tacgtcgcgc
     8581 tccaggggaa cctgtcctac ctgatctccg gctgggtcaa gctgctcggt cccgactggc
     8641 ggtcgggggc cgcgctggcg ggggtgatgc ggaccaggac gtacgggcac gagggagtat
     8701 ggaagctggc ccatcgccac ccgcgcacga cccgcgccct cgtctacggc gtgctcggcc
     8761 tggagtgcct gttcccggtc ctctatctga ggggcggccg gctgacccgc ccggtgctgg
     8821 gaggtgccgt cctcttccac ctggccaacg gctacgtcat gggcctcggc aggttcctcc
     8881 cggccttcgc cgcgatgcac ccgatggtcg cctacaccag cacgccgcgc agccaccccg
     8941 cggcggcggg ccgcgacgac accatgccgg ccgcggtggc cctgctggcc gcgggcggcg
     9001 cggccgtgct ggggacggtc gcggcggccc ggcggctgcg cgtcaccgac accccgcacg
     9061 gcggcaccgc cgtcaccacc cggcacggca acgaactgag cgtgcagggc accctcgacg
     9121 gccggagtac ggacccggtg gtggtcttcg tccacggact gggcgcctgt cccgcgtact
     9181 tcgcctggat cgcccgcgcc ttcggcgcgg accggccgtg gctgatgtac aacagggccg
     9241 gctacggccc cagccgacgc cgcgcggacg gggagttcac gctggaggag tcggtcgacg
     9301 acctggtcga cctggtcgaa gcggcggtac ccgaggggcg ccaggtggcg ctgatgggcc
     9361 actccctggg cggcgagatc tcccgccgcg ctgcggtcag gctgggatcc cgggtgaact
     9421 ccgtcatcta cgtggacagt tcgcaccccg gacagctcac ccggtcggcg cagcagggcg
     9481 cgaccgcgcc gcggatcggg gagggcctgc gcaccatggc catcagtctg cggctggggt
     9541 tcgggtcgct gatgcggacg cccgatccgg tcgccaacct ccccgaacag gtgcgggaca
     9601 aggtcaggat ggagttcgcg gactcccgcg tgtggaccgc cgcggtgcgt gagtggaagg
     9661 ccgtcgagca ggacttcccc tccttcaccg ggccgctcga cgccctggac acccacgctc
     9721 tggtgctctc cgcccagcgg accgtggacc gcgaccccga ccacctgctg atgcacaagg
     9781 acctcgccga cgcccaccac ggggaccgga ccgtccgaag cgccgtcatc gagggcgccg
     9841 accacgacgg catcctcacc gacccccagt acgccgccgc gacactccgc cacctgctgg
     9901 ccttcctggc cgacaccgcc gcgcgggaac cggaggcacg gcccggactc ccggccggga
     9961 cggagccgtc cggcctgacc gccgcgtccg aggagaaccg atgagcactc cccgtctccc
    10021 gtccgccacc ggctcgctgc tgacccgcgc cttcggcggc gcggacggca aggtccgcct
    10081 cgccgcaggc gtcgtcttcc tcggcgccat ctgctgccag cacccgcacc cgtccttcga
    10141 ccgggtccag aggctcgacc cgctctccag cgtcttcccc aactggcgct tcttcgcccc
    10201 gactccggcc cagcacgact tccagttcta ctaccgcacc ctcgacgtgg cgggggagac
    10261 ctccgactgg accgcgctgg aggtcatcca gggccgccgc ccccgccaga tcgtctggtt
    10321 ccccgaacgg cgggccgaga aggcggtgta cgacctcggc agcgagatcc tgcgcgtcct
    10381 cgaccgcggg ttcgaggtgg ccgtgaccct gcccgccttc cgcatcctgc gcagcttctt
    10441 ccgcgaggag atcgagcggt ccggcacgcc ggacgtcaag ggcttccagt tcgccctggt
    10501 ccaggactcg ggctacgaca agaccgagga gcccgagatc atcttcctct ccccctacac
    10561 accgatgcgc gagaccgcgg caccggcgcg agaaagcgag accgtatgag caccgccact
    10621 ccctccggaa cctccgtggc gacctctccc gaggtccagg acatcggcta cggaagggtg
    10681 ttcgccgact tctacgaccg cctgctgccc cacgacggtt ccgccgaaca gaccgccggt
    10741 gtcctcgcct cctggcatcc cggcggcgcc accctcgaac tcggcgtggg caccggacgc
    10801 gtcgccgtcc cgctggcccg gctcgtcggc gaggtcgtcg gcgtggactc ctcgccggag
    10861 atgctccggc ggctctgcga aaccgtcgac gccaccggcg ccccggtcac ccccgtgcac
    10921 ggcgacatcc gcacctacgc cgacgactcc cggtacgggc tggtctactg cgtctgcgcg
    10981 accctctcac tggtctgcga cccggcggag cagcggacgg ccgtcgcccg ggcggcccgg
    11041 caactggcgc ccggcggcac cctcgtcgtg gagacccaca accccggctt cgtgaccgcc
    11101 ctgcacgagg ggcgcgcccg cacctccttc ttcattccgt acgccgaacc gggcgccggg
    11161 gtgcagacct actccaccct gatccccggc gggctctggc acgcctcgca cctggtgcac
    11221 gggggcggcc gggtgagcat cggcaccgag gtcacccggc tcaccaccgc cgaggacgtc
    11281 gactcctacg cggccgacgc cggtctcgtc ctggtgtccc ggcacggcga ctgggcgggc
    11341 ggcccgttcc tgccggaggg gagcggtgtc cacatcagcc gctaccgccg ccccgcctcc
    11401 ggtgaggagc ggtcatgacg gccaccgcgg cggcgtccgg cggcgccgtt cggaacctga
    11461 cgcgcgggca gtggcggctg ctgctcgggg gcaccgccct cgggctgctg ggcgtggtgt
    11521 gcaccctggc acagccggtg ttgctggccg acctgatcag ggccgccggg gaccaccgcc
    11581 cggtggtcgg ggtcgtcgtg gcgctggtgg tgctcttcct gctggacgcc gcgctctccg
    11641 ccgcccaggg ctgtctcatc ggccgggcgg gggagaacat cgtccgtgac gcccgggtcc
    11701 tgctctcggg caaggtgctc cgggcggacc gcgcgcacct cgacacccgg cgccagggcg
    11761 acctgcacac ccggctggtc gccgacacct ccctgatgaa gatcgcgctc acccagagcc
    11821 tcgcccagat cgtcctcaac gggctgatcg tggtcggcgc cgtggtgatg atggcgttca
    11881 ccgacatctg gctgcttctg atcgccgtcg gatgcctcgc cgtcgccggg accgggtcgg
    11941 tgtggctggc ccgcaggctg cgccgggccg ccctcgccaa ccgggaggac atcggcgact
    12001 tcggcgccga cctccagcgc gtgctcaccg ccctgacgac ggtgaaggcc gccaacgccg
    12061 agggccgcga gcagagccgc ctggcggagt ccgcagaccg ggcccgcgtc tccggcaacc
    12121 gggtcaccgt gctcaacgcc ctgttcacgc ccgcgctgaa cgtcggtctc caggcgtcgc
    12181 tcgccgccgt gatgggcatc ggcatggccc gcgtcgtcag cggctccatc agcctggccg
    12241 acttctcggc gttcgcgatg tacctgttct acctggtgtc gccgctggtc ctggtcttcc
    12301 tctcgatcgg cacctacctc cagggccggg cggccgtcca gcgcgtggac gaactcgaca
    12361 ccctgccgca ggaggacgaa cacccctccg gcgatgcgga cgcggccgcc ggccggagcg
    12421 gtgcccccgc cgacgagccg tccgtccgtc cggccccgca gggcggccac cccgcggtgg
    12481 agttccgcga cgtctccttc ggctacggcg accggccggt gctggaaggt gtgtcgttca
    12541 ccgtccccgc ccacgggctc accgccgtgg tgggcgcctc cggcgcgggc aagaccacgg
    12601 tcttccagct catcgagcgg ttctaccggc ccgggggcgg cgcgatcctc ctcgccggcc
    12661 gggacatcgc ccacctcccg accgccgagg tccgcggccg cgtcggctac gtccagcagg
    12721 acaacgccgc gatgcgcgga accctccgcg agaacatcgt gtacgcggcg cccgacgcca
    12781 ccgaggccga gatcgccgag gccgtcgaac tcgccggtct caccgaggtg gtggcggaac
    12841 tcccggacgg cctcgaaacc ctcctcggcg accagggcac cgggctctcc ggcggtcagc
    12901 ggcaacggct ctgcgtggcc agggcgttgc tccagaagcc ggacgtgatg ctgctcgacg
    12961 aggccaccgc ccacctggac tccgacaccg aggcggtgct gcgcgacagc ctgcgcggca
    13021 tcgcggagcg gtgcgccgtc gtcgccatcg cccaccggat ctccacggtg gccgaggccg
    13081 accggatcgt ggtcctggac gagggccggg tgcgcgcagt gggtacgcac accgaactcc
    13141 tgcgcgacga cgccctctac cggcggctgg ccgccaccca gttcgccgac ggccccctcg
    13201 gcggacgacc cgcgccggac cccgtaccgg acatcgccaa gagcgcgcag ccgggctccg
    13261 atccggtgcc cgagccggtc ccggccgcac tgccgggccc gggagccgtc cggtgagcac
    13321 cgtggacacg acggccgtgg gcagcggccc ggacaagccg gccgccgcgg tcaccccggc
    13381 tcgcgcccac cacggccgcg ccacgggccc cggaccggcc ccgtactaga ggttcaccgc
    13441 gcgccccggt ccccggtccc ggtgtgaccg acccggggcg cgaggtggcc gggtggcctc
    13501 cggcgcgggc gtacgccctc ttttgcacgg gcagcgtgtg cgacacgctg cccgtgctcg
    13561 gcccgttccg gcgcgggaac cccggccgca tgacgacccg ggcccggaga gtcacaccca
    13621 gccgcgctcg cgggccagca gcgccgcctg ggccctgctg cacgcgccca gcagggccag
    13681 gagatcggag acatggcgcc ggtaggtgcg cagcgacatg cccgccgccc gggcgcccgt
    13741 ctcgtccttg gtggtggtgc acatgaggag cagtaccgtg cgctgggccc cggtgagggt
    13801 gccggtgccc gccttcgacg gggggaggtc gacgaggtcc gtcgctgtcg cccacaaccc
    13861 ctcgaagagc gtgacgagac tgcccaccag cccgctctcc tcgatgcaga gcacgccccg
    13921 gtcgatgtcg tgcgcgtcga cggggaccag cgcggtgcgc cggtcgtaga ccagcaccag
    13981 ctccgacagc ccctccacga ccctgacctc cgcgccgtgg gagcgcagtt gccggaggtg
    14041 ttccgagccg gttccgggtg ccggagcccc gctctccagc agggtccgca cccggacgcc
    14101 gcgccgtagg cagttcagtc cgagtgagag ggtgtgggcc gtgttcagcg gtaccagggc
    14161 ccggttgggg atcgccgcca ggatctcggc gtcggcgtgg aaggccgccc ggtcgatccg
    14221 ggcgagggcc tgccccagat cctccaggcg gtccagggcg atcgcggacc ccgcgtagac
    14281 acccccgccg cccgcgaagg agcgggcggg cacgtcccgc cacagggagc gcaggatcgg
    14341 ccgcgggtcg gcgaggcggc gcagcgtccg gtaggcggcg tccaactgct cctccgccag
    14401 ccgggccacg acgacccccg ggtccgtggc ccaggtccgc gcctcgctcc cgtgcagcag
    14461 cccccggtcg cgcagccgcg ccgcggccag ccgcacgccc tcctcgtcca tcggcgcggc
    14521 ggtgcgcgcg tcaccgacgg cggcgccggg attccgtagg aagaagcggt acaccctctc
    14581 ctcggtgctg ctcagaccga gtggcgacat cgtgtaggtc cccatggccc ttccctcgaa
    14641 cacgtccggc gggacaacgg atcacaagtc tgcccgggga ggcgggaggt gaggtctcag
    14701 cgaagtctca agcctccctg gcaccaggga agttccgtat gcgtgaccac ttgaaggaac
    14761 gggctccgat cgctatgaca ggaggccgtg caccgaagtg atcctggagg ttcgatggcc
    14821 gatgcacccg cagccgcccc gccggtacag gccacgccgc actccctgcg ggaggtggtg
    14881 gcaagccgtg atctggccaa tctcaccggc ccgctcggca gcgggaagtc ccggttagtc
    14941 gccgggctcg gctccgtctc cctcctcgac ctcgaccggc ccggcgccct ggagcggctg
    15001 ccggccgcgc tcgccgagcc cacctcggcc ccgctggtcg tggacagcgc ggacggcgac
    15061 cacgccctgg ccgcgctgga gccgctgcgg ctgcgcccgc cgggaagcgg ccggcccgtc
    15121 ctcgtgatca gcaggcgctc cctgctggcc cggccggggt gggccgacac gggggtcgcg
    15181 gtcatggaga ccggcccgtg gccggacgcg cggatcgggc gtctggccac ggaggcgcgg
    15241 gtgaccgacg cgcggtgccg ggaactcatc gtccggctcg ccgcgggcaa cccgctgatc
    15301 gccgacgcgg cctgccgggc cgtgcacgcg ggtgcgccgc cgaccgccgc cggggcggtg
    15361 gccgacggtg ccgcccggga gatcgtggag cggctctccc gggagcggcc caccgggccg
    15421 tggcagcagg ccctcgtccg gctggccacc gtctggtcgg cggacgagga actgctcgac
    15481 gccgaaccgg agttgttcga caccctggcc gggctcagcc cggtcgtccc caccgaactc
    15541 gggttggccc tcacggaacc cttccgcggg gtgatcgaac tggcccatcg ctggcggcgg
    15601 cccgccgccc accgcggtac gtgggcccgc gcgctggccc accgcaagaa gctgctggcc
    15661 gacgaacccg ccgccgaccg ccgcagccgt ctcaccgagg ggatcatcgc cctggccgac
    15721 gacgacgcgg tccgcgagac catgttcccc atcagcgtga cccgggacgt gatccacacc
    15781 gccaccccgg acgacgccga cgccatcggc accctgatgc gccagtgggc ccggcagggc
    15841 ggcctggaca cgcggtggac cgaccgcctg gtggaacgct ggctcgtcga tgaccccgcc
    15901 agctttcagc tgatccgtga cggcggcgac cggatcatcg gcctgaccaa cacccagcag
    15961 gtcaccgaac gcaccgtgaa ctgtgtggaa cccctgctcc agcagcacac ggaccggctg
    16021 ctcgaccgtc cgcgcggaac cggcggatgg ctgctcggcg cggcctactg ccccgaccgg
    16081 ggcgcccacg cacacctgct gcgcggcctg ttgcgccagg tcatcatggg cggcctgctg
    16141 ctgacggtgt ccactccgaa cccggactac cagcggctgc tgcgcgggct gcgtttccag
    16201 cgtcacggca ccaccaccga cgacgtctac cgctgcggcc gcaagcccga gatcttcagc
    16261 caggacttcg gatccgccgc gctgcccgac tggacggagc ggctcgcccg cgcctcgggg
    16321 gtgcgccgcg gcccgcgtcc gaccggccag gaggtggccc gtgccctcgc cgccatcgcc
    16381 gacccggccc ggctcgcgga gagcccgctg ctcctctcgc cacgcacccg gacggtggcg
    16441 gaactgcgcg cggacctggg ggaggcggtg cgacggctgg cggacagcga ggtgcaggag
    16501 gaggccgagg ccgggtggat cctccagcac tactacctcg gacggccgcg gacccatcag
    16561 cggctcgccc agcagctcca catcagccgg gccacctact tccggcggct ccggtacggc
    16621 ctggaccggg tgggcgacgg actcgcggcg gaacggagcg tcccatgagc ggcggccggg
    16681 aggaacgccc cggtcagcgg cgggctccgg cgaccacgac cagcagcgga acgagccggg
    16741 agggagggat ccgatagcgc ccacctccgg ccgtctccag ccagccggcg gagacgagtt
    16801 gccgcaggtg gtggtagatc tgcccggtcg taccgagccc ctccagctcc atgagctcgg
    16861 tcaccgcggt ccgtccctcg gccaaggcct ggatcaggcg cagccgcacg gggtgcccca
    16921 gggctccgag cgtctcggcc gtctcggacc agtcggaacc caacaccgac tccgtggctt
    16981 cggaccgttc ccactccacc ggctcaccgt ccggaccggc cacagacccg gcgaagacca
    17041 ctccccttcg tgccgcttcc tccagtcgct cccgaagtcc cggcaacgcc ccctgggctt
    17101 cgatcgacgc gacgtcggca ccaggctcag gcgtggaccc ccggactcgc tcctcaagct
    17161 cggagatccg ccgagagacc tcggcgacct gcccgaccag cgcgtcccac gacggcgcag
    17221 catcacccat tcggccagcc tagcgtcgga ggcgcccgca cggtcccggc ccatcgaagt
    17281 ggacccgcgg tcagcgcgga cgggccgtcc tccgcggcga cggcggaccc gtgggcggaa
    17341 cgcggcagga agccccgacg gtcgtacagg tccggtcccg acggccgtcc gggtctggtc
    17401 cggtcccgac ggccgtccgg gtccggtccg atcccggacg gcagtccagg tccggtcccg
    17461 actgccgtcc agggcctgtc cggcccggat gaccggaccg ccggacatca cgtcttctcc
    17521 tgcgcctcgg tacggagtcg gcgggccccc gcggtcaatt gggcgaccag ctcccgtttg
    17581 agtaccttgc cgctggggcc gagggggaag gcgtccacga actccacgca gcgcgggtac
    17641 ttgtacggtg ccatgcgctc cttgctccag gcgacgatct cggcgcccag ggccgggccc
    17701 ggcaccgtgc cggggcgggg cctcaccacc gcgcacacct cctcaccgtg gacggggtgg
    17761 gggagtccga cgacggccgc ctgggcgatc gccgggtggc gggccaggac gtcctccacc
    17821 tcgcgcgggt agacgttgta cccgccgcgc aggaccacgt ccttcttgcg gtcgacgacg
    17881 gacagatagc cctcgtcgtc cttgacgccc aggtcacccg agcggaacca gccgtccacg
    17941 atggcctcgg cggtcgcctc cggccggttc agatagccgg ccatcacgtt gtgcccccgg
    18001 atgacgatct ccccggtctc gcctgcgggc agcagttcga tcctgtcctc cacctcggct
    18061 ctggcgatct cgacctcgac gccccagatc ggccggccca ccgtgcccgg tcggagcggc
    18121 cacgccttct ggttgtaggc caccaccggg gaggtctcgg tcagtccgta cccttcgagg
    18181 accgggcagc cgaacgtctc ccggaacgcg tccaggaccg ccaccggcag cgcggcgcca
    18241 ccggagaacg cacggtcgag cgcgggtcgg cgcgggtcgg cgcgggccgc ttcgaggagg
    18301 gcggtgtaca tcgtcggcac ccccatgaac acggtgcagc gctcccgcac catgaggtcc
    18361 agcgcgcccg gcccgtcgaa ccggggcatc agcaccaggg tcgcccccgc ccggaagcag
    18421 gtgttcatgc cgcagatctg accgaaggtg tggaagaggg gcagacagcc gagcaggacg
    18481 tcgtccgcgg tgaagtcgaa cggcgacagc atggtcgtgt cgacgttcat caccacgttg
    18541 agatgggtga gcagggcgcc cttgggcctg cccgtggtgc cggaggtgta gaggatcacg
    18601 gcgatgtcct cgggcgcgcg cgccacctga cggccgatcg gggcggtccg cgccgcgagc
    18661 gcgtccagcc tcggggcgtg ggcgaactcc gcttctgcgc caccctcctc cgccatgacg
    18721 gtcagtacgg gcgtgccggt cgtctccgcc gccctgccgc cctcggccag cagcggggcg
    18781 gcgcagatca gcgccgccgc cccggagtcc ttcaggacgt acgcgatctc gtcggcccgg
    18841 agcagcgcgt ggaccgggac cgcgatcccg ccgagcgcga gcaccccgaa gtacgccgac
    18901 gggaagtgcg gcgtgctggg cagcagcagc gccaccttgt cgccggggcc gatgccccgc
    18961 gcgcccagcg ccgccgcgta cctccgtgcc tcgtcccaca gttcgcggta ggtgatcttc
    19021 cgcgtaccgg ccacgaccgc cgggtgctcc ggtcgccgca gcgcggactc ggcgaggacg
    19081 gacgccaggg agagggtcac gggtgtctca cccgctcgct tccgcggcca gccgcgcctt
    19141 gtccggtttg ccgacgccgg tgaggggcag agcggggcgg atgtggatcc gcgcgggaac
    19201 gtgcttgggc gagatggcgg cccggatgtg ttccgccagt gtgtcggggg tggccgcggc
    19261 cgcctcgcgc agcaccacgg cggcgtgcag gtgctcgacc cggtcccggt cccggacgca
    19321 gaagacggcg gcctggacga catcgggatg cgccaggaac gcgttctcca cggtcaccgg
    19381 atggatcttg atgccgttgg tcttgaccac ctcaccgatc cggccacgca ggtggaggta
    19441 gccgtcgccg tcgacgaagc cgaggtcgcc ggtgtgcacc cagccgtccc gtacggtccg
    19501 ggcggtgagc tcgggctcgg ccacgtacgc gctcatcgtg aacggcgacc gtacgcagac
    19561 ctcgccggtc tcgccgggcg gcagatcgcg gtggtcctcc gggtcggtga tccggaccca
    19621 gccgggcatc ggccggccga ccgtgacacg cagccgggga tcgaggtgct cggcgggcga
    19681 gagcatgctg acgaagcccg cctcgctggt cgcgtacacc tggatcagta cgtccccgaa
    19741 gaccttgacc gcctcgccca gccgctcggg ggaggcgggg cagcccacgt acgtgaccat
    19801 cgtgaggctg gagaggtcgg tcgagtccac ctccggatgg tccatgagca gatacagctg
    19861 gggaggggag agcagcatcc tggtgatccc gtgccgttcg atgcggtgca gcacgtcacc
    19921 cgggtcgaag ccgtcccgca ggaccaccga accgccggac gcgagcgagt cgtccgccgt
    19981 ggcgccgctg gagtggctca gcgggaggca ggccaggtag accgaccgcc agcccatctg
    20041 caatccggcg gagatgaacc cgttgcgggc ccggaagtcg aaggcgatgc ccttcggctc
    20101 accggtcgtc ccgctggtgt aggtcaccac cgcgggccgg tcgggcggga tcgcgacggt
    20161 gtccgggtcc agtgcgtccg ggtcccccgc cgtcagatcc aggacatcgg ggccgaggtc
    20221 gtcgagggag gcgagggtga ggggagtgcc cagccgctcg cgcagctcac gcgcggacgc
    20281 gaggttctcc gcgtcgacgg ccagatacgt cgcgccggtc tcccggagga ccttgagccg
    20341 ggcgtcggcg gccaggtggt ccgccgggtc caccgcgttg gtggtgtgca gatgcaccac
    20401 cgtggccccg gccagattcg cggcgtaccg caggaccagg gtcggggcgg tgttggtgac
    20461 ggtcaggatg gcgaccaccg ccccgccgtc ggtcccgccg gcgtgctggt gcagggtccg
    20521 cgcggccgac cggaccagag tggtcagctc cgccgcggtg agcgtcctgc cgcgccagga
    20581 caggacgact ttctccggtt ccgcggagat cacctgaagg atctggctga catacgtttc
    20641 gttcgacggc ataggaaact ccagtggtgc cgtggcgagg aatttccgca gagcctacaa
    20701 caagggaatg cggtgtacca ggagtacgaa ggggagaagc gggtgcgcgg gcggaaatga
    20761 attgtcgcag gccgcgccat cgaagtgata tgcggccctg agacaatacc ctctaccgat
    20821 tcggcccccg catcggttcg gtcttcggag aaaagggtcg tcatgaacca ttacctggag
    20881 ctcttctcgc ggaacatggg cgaaggcggg gcgccggatg cgaaacggga gttcctcgaa
    20941 ctgggccggc tcgccggaaa attcccggcg gcccggagcc tgcgggacgg ggtcacctcc
    21001 gagatcagcg tgtggtgcag caacgactac ctgggaatgg gccagcaccc actggttctg
    21061 gcggcgaccc gcgaagccct cgacgagtac ggtgcgggct cgggcggctc ccggaacatc
    21121 gccgggacca accactacca cgtactgctg gagaaggaac tcgcggatct gcacggaaag
    21181 gcggacgccc ttctcttcac ctccggttac accgccaacg acggagccct cacggtcctc
    21241 gcgggactgc cggagaaatg cgtcgtcttc tccgacgaga tgaaccacgc ctcgatcatc
    21301 gacggactcc gccacagcgg cgccgagaaa cgcattttcc ggcacaacga cacggcacat
    21361 ctcgaagagc tgatatcggc caccgatccc gaccggccga agatgatcgt catggagtcg
    21421 gtctattcga tggggggaga tgtcgccccg ctcgccgaga tcgcccggat cgcccgcgag
    21481 cacggcgcga tgaccttcct cgacgaggtg cacgcggtcg gcatgtacgg gccggaggga
    21541 gccggtatcg ccgcgggcct cggcatcgcg gacgagttca ccgtcatcat ggggacgctc
    21601 gccaagggat tcggcaccac cggggggtac atcgccgggc ccgccgagct ggtcgacgcg
    21661 gtgcgcggcc tctcccgccc cttcatcttc accaccgccc tgcccccggc ggtcgcggcg
    21721 ggcgcgctcg ccgcggtccg gcacctgcgc acctcggagg aggaacgcga ccggctccgc
    21781 gagaacgcgc ggctgacgca ccgcctgctg agggaacgtg ccatcccctt cctctccgac
    21841 gggtcccaca tcgtctcgat cttcgtcggg gacgacgcac tcgcccggcg gatctccgcg
    21901 ctgctgctgg cccgccacgg catctacgtc caggcggtca acgcaccgag cgtgcgcgtg
    21961 gggcaggaga tcctcaggag cgcacccggt gccgtccacg agcccgcgga catcgagggg
    22021 ttcgtcacgg cgctggacga catctggcgg gaactggggg tgacgcgggc ccagggcccg
    22081 cacatgccct ccggaacgga cggctgaccc tcccacgcgg tgcgctgtcc cttcccccgc
    22141 ggtgagttgt ccctttcacg cggtgcgctg caccttcccc gcggtgaggt gcccttccca
    22201 cgcggcgaga tgcccctccg tcgcccgtgc gtgaggcggt gcctcctccg cttctccgct
    22261 ccacgaactg cccgcccccc gtacgcgtag cggccggtgt gccgcttccc gtacccgatg
    22321 cggctggcgt gtcgctcccc gtccccgatg cggccggtgt gccgcttcgg cagcgtgggg
    22381 cgtcctgtcg cggcctgcga tatcgggccg ctatgcgccc tcggcaagat cgacgtcggc
    22441 gggaccggcg gcggtacaca tcggccatga cgaaggcgtc ccggccgacg cacgacccgt
    22501 ggcggcgggc accccgccac ggtccggtga ctgatggtcc tgctcgccgc gaaggagtcc
    22561 gagaacacga tggcgcaccc cgacggtacg gaagcaccgc tgctgtggac gctggccggc
    22621 aacggcaggc aggcgctggc ggccggtgcg cgcggtctgc acacgtacct ggccggccat
    22681 gacgactgga gcccccagga catcgcgctc accctcgcgc gcaccgcttc ggagggaagc
    22741 cggcgggcgg cactggtggc ggacggccgg gacgggttcc tgcggcggct ggacgcgctc
    22801 gccgacggca ggagcacgcc cggcctgctg gagggccccg ccggggtcgg cggccgggtc
    22861 gccttcgtgt ttcccgggca gggcgcgcag tggccccgga tggcggtgga cctgctggac
    22921 acctccccgg tgttccgcga ccggatggac gcgtgcgcgc aggccctgga accgttcgtc
    22981 gactggtcgc ccctcgacgt gctccgcgcc ccggacgcgc cgggcgcacc cgccggggac
    23041 cgcgccgacg tggtgcagcc cctgctgttc gccgtgacgg tgtcgctcac cgcgctgtgg
    23101 cgctcgcacg gggtggaacc ggccgccgtg ctcggccaca gcgtcggaga ggtcacggca
    23161 gccgcggtct ccggcgcgct ctccctggac gactccgcgc gggtggtggc cctgtggagc
    23221 caggcccagg cgaccctggc aggtcagggc gacatggtct ccgtcatggc cccggccgac
    23281 gaggtcgagc cgaggctgcg ccgctgggag ggccgcctcg tcgtcgccgc gcacaacggc
    23341 ccccggtccg tgatcgtctc cggcgaccgc gacgccgcgg ccgaactcct cgacgccctg
    23401 gccgcggacg cggtgcacgc ccggcggatc gccgtgggcc tggccgccca ttccccccac
    23461 atcgacgcga tcatcccccg gatgcgcgcc gacctcgccc cgatccgccc ccgtacaccg
    23521 cggctgccct actactccgg cctgaccggc ggacgactgg acgcgccggt actggacgcc
    23581 gactactggt gccgcaacct gcgcaacacg gtcaggttcc accaggcggc cggggccctc
    23641 ctgcgggacg ggcacggtgt cctgctggag gtcagtccgc acaccgtgct gacctccgcc
    23701 ctcacggact gcgtggagga acagggtgcc gaggccgccg tcctggggac gctgcgccgc
    23761 gaccagggcg gtccgggccg gttcctgacc tcgctcggtg acctgtacgt acgcggagtg
    23821 cccgcgcacc gggaggctcc ctccgccgtg gagcacgccc gggtacggga gttgccgacg
    23881 gcggtcctga ccgccctcgc ggacaccggc ccggcggacg tgaacgggac ggacggtacg
    23941 gacggtgagg agggcggcgc cgcgttccgt gcggagctgg ccgccatgga cgtacgggag
    24001 cggcgcgccg cgctggcacg cctcgtgggc gaggagatcg ccgcgctgac cggacggtcc
    24061 gatcccgtcc ccgccgaact ggcctttctc gacctgggat tcgactccgt gaccgccgtg
    24121 gagctgcgca accggctggg cgcggcgacg gcgctgcgca tcccggcgac ggtcgtcttc
    24181 gactgcccga ccccggcggc cctgaccgcg tacctcagca ccgcgatcgg cggcgaccgg
    24241 tccggcacgg acgcggccac cgatacgaac gcggtcacgg ccgtgccggt gcggcgtcct
    24301 gtggacgacg accccgtggt gatcgtcggc atgggctgcc gctaccccgg aggtgtcggc
    24361 agccccgacg aactctggga gctggtgtcc tcgggcgccg acgccgtctc ggcgctcccc
    24421 gccgaccggg gctgggacac cgccggacgg tacgaccccg caccggggac gccgggccgc
    24481 tactaccagc gggaggcggg ctcgctcgcc ggtgcggccg agttcgacgc ggagttcttc
    24541 ggcatctcgc cgcgcgaggc ggcggcgatg gacccgcagc agcggctgct gctggagacg
    24601 gcgtgggagg tgctggagcg ggccggcatt gacccggtca ccctgcggcg gaccccgacg
    24661 ggcgtctacg tcggagcgat gaccatggat tacggcccct ccctcgaaca gggcgccgac
    24721 gagggcggcc acctgctgac cggcaacacc ggaagcgtcg catcgggccg gctggcctac
    24781 accctcgggc tggagggagc ggcggtcacg gtggacacgg cgtgctcgtc ctcgctggtg
    24841 gccctgcatc tcgcggtccg ggcgctgcgg tcgggcgagt gctcgctcgc cctggccggc
    24901 ggagcgaccg tgatgtccac ggtcggcatg ctcgtggagt tcagccgtca gggcggcctg
    24961 gccccggacg gccgctgcaa ggccttcgcg gcggcggccg acggcttcgg cctggccgag
    25021 ggcgtgggga tgctgttgct ggagcgactg tcggacgcgc ggcgcaacgg gcatccggtg
    25081 ctggccgtca tccgtggctc ggcggtcaac caggacggcg cgagcaacgg cctgacggcg
    25141 ccgagcggcc cctcccaaca gcgggtgatc cgtgcggcgt tggcggacgc ggggctggcg
    25201 gcgtcggacg tggacgtggt ggaggcgcac ggtacgggga ccaggctggg tgacccgatc
    25261 gaggcgcagg cgctgctggc gacgtacggg caggaccggc ccggtgaccg tcccgtctgg
    25321 atcggctcac tgaagtccaa catcggacac acccaggccg cggcgggcgt gggcggtgtc
    25381 atcaagtcgg tgctggcgat gcggcacggg gtgatgccca ggacgctgca tgtggacggg
    25441 ccgacgcccg aggtggactg ggcggcgggg gcaggccagt tgctgacgga ggcccgtacg
    25501 tgggacgaca cgggccgccc gcggcgggcc ggagtctcct ccttcggcat cagcgggacc
    25561 aacgcccacg tgatcctgga ggctgccccg gccgaggccc cggccacggt ggtggagagt
    25621 gccccgcgtt ccggggccgt ggtgtggccg gtgtcggcgc gcagcgcgga ggctctgcgg
    25681 gcgcaggcgg gcgcactggc agcacgggtg gccgcggagc ccgcgctcga cgcggtggac
    25741 gtgggctact cgctggcggt ggggcgtgcg tccttcgagc accgcgcagc ggtggtgggc
    25801 ggcgaccgga gcgaactgct ccgtggggtg agggcgctgg cggaggggcg ttcggcccag
    25861 gtgccggggc tggtgcgggg cggcggggtg tcgtcggggc gttcggtcct cgtattccct
    25921 ggtcagggtt cgcagtgggt ggggatggct gcggagttgg cggcggagtc gggggttttc
    25981 gcggggcgga tgggtgagtg cgagcgggcg ctctctccgt acgtcgactg gtcgttgacg
    26041 gaagtgctgg gctcggagcg gttgttggcg cgggtcgatg tggtgcagcc ggtcctgtgg
    26101 gccgtgatgg tgtcgctggc ggaggtgtgg cggtcgttcg gggtggttgt ggatggcgtg
    26161 gtgggtcatt cgcaggggga ggtggcggct gcctgcgtgg cgggtgggtt gagtctggag
    26221 gacggggcgc gtgtggtggc gttgcgttcc cgtgcggtgg gggtgttggc ggggcgtggt
    26281 ggcatggcct caatcccctt gccggtggac gtggtgcggg aacgcctcgt cggctggtcg
    26341 gggcggctgt cggtggccgc tgtcaacggc ccctcctcga cggtcgtttc gggtgatgcg
    26401 gacgccgtcg ccgggctcct ggaagtgctg gccggtgagg gggtccgggc ccgtcgtgtc
    26461 gaggtggatt acgcgtcgca ttcctcccat gtggaggcga tccgcgagca gttgctcgtc
    26521 gggctgaagg acatcacgcc gcgtacgggc tcggtgccgt tctattcgag cgtgaccgga
    26581 ggcctgttgg acacgaaggg tctggacgcg gagtactggt accggaatct gcgcgagacc
    26641 gtcgagttcg ggaaggcgac ggaggcgctg ctgggggagg ggttccggtt cttcgtcgag
    26701 gccagtccgc atccggtgct gggtgtggcg gtgggggagt ccgtggaggc cgccggcgtg
    26761 gacgctgcgg cgcttgggac cctgcggcgc ggtgagggcg gccaggagca ggtgttgcgt
    26821 gcggtgggcc gtgcctggga gcgcggactg gacgtggact ggtccggg
//
