LOCUS       NZ_ARPF01000007        36371 bp    DNA     linear   CON 18-FEB-2024
DEFINITION  Streptomyces sp. SolWspMP-sol2th B083DRAFT_scaffold_6.7_C, whole
            genome shotgun sequence.
ACCESSION   NZ_ARPF01000007
VERSION     NZ_ARPF01000007.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. SolWspMP-sol2th
  ORGANISM  Streptomyces sp. SolWspMP-sol2th
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 501280)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Improved High-Quality Draft of Streptomyces sp. SolWspMP-sol2th
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 501280)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces sp. SolWspMP-sol2th
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/18/2024 03:17:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,475
            CDSs (total)                      :: 6,400
            Genes (coding)                    :: 6,297
            CDSs (with protein)               :: 6,297
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 31 of 103
            Pseudo Genes (incomplete)         :: 82 of 103
            Pseudo Genes (internal stop)      :: 12 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:24:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 464909
            Orig. end                         :: 501280
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ARPF01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..36371
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="7"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..36371
                     /SMILES="NC([*])C(=O)NC([*])C(=O)NC(CO)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..36371
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:33697](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..33697
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    248..262
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(474..740)
                     /locus_tag="B083_RS0118370"
     CDS             complement(474..740)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487454.1"
                     /locus_tag="B083_RS0118370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028417987.1"
                     /transl_table=11
                     /translation="MSHPQSYELLLIPDHSRTRTGAPGRPLRSAVVSATGKTGASGYPR
                     YTGEGMEADIDPETRTVEAVLVDGEELDPGMSVQVADGVRPTG"
     gene            complement(795..1817)
                     /locus_tag="B083_RS0118375"
     CDS             complement(795..1817)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513044.1"
                     /locus_tag="B083_RS0118375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_028417988.1"
                     /transl_table=11
                     /translation="MSQLPKQPTEVSVPTSADVARLAGVSRATVSYVLNNNAAVRISEP
                     TRHRVREAATQLGYVPHAAARSLRAGHSRLVLLPSGHIPSGPLHQHFFQELQAGLRRLD
                     YTVVQYGSAGLADDEAVRAWAELRPVAVVVPPGITLTPHGTDVLTRSGAKAVITLGPEP
                     VAGAHGLVMDQRRVGASAVAHLLARGRRRIGVVMPREPGLTPFSEPRLAGARQTAEPAG
                     ARVHPLPLGYEEESAAELAGRWRDLGLDAVFAYNDEYAMLLMRALQDAGVAIPGDTAVI
                     GADDLLLGRLLRPRLSTVRMELAMDQPLAETIDRLVHHPGTAPVHQDLLRTGAVHRDSS
                     "
     misc_feature    complement(1806..1808)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1949..2416
                     /locus_tag="B083_RS0118380"
     CDS             1949..2416
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612917.1"
                     /locus_tag="B083_RS0118380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_018487452.1"
                     /transl_table=11
                     /translation="MTFHHSAERTDSPSVLPGSTGPTATVQADPRAVGPVRTSYAPDRD
                     GDPDPGEIVWTWVPFEENDGRGKDRPVLVVAREAAGTLLAVQLSSKQHDMDHEWVALGA
                     GPWDSSGRPSWVDLDRVLRVHEDGMRREACALDRDRFDTVTGRLRERYGWS"
     gene            complement(2618..3451)
                     /locus_tag="B083_RS0118385"
     CDS             complement(2618..3451)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487451.1"
                     /locus_tag="B083_RS0118385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR02452 family protein"
                     /protein_id="WP_028417989.1"
                     /transl_table=11
                     /translation="MSARLRGIARETEAVVEAGHYRNAAGHAVSIERAVAAARSGTRLY
                     GPAPVPVTAPATDRTPRFEVTGESSLRAARRMAEEAPGKVAVLSYASARNPGGGYLNGA
                     QAQEEALCRGSALHTTLLRAPAYYAHHRADRSPFYTDRVIHSPGVPVFRDDRGGFLDTP
                     YEAGFLTSPAPNAGVIRRQVPEEAHRVPAALAARAERVLEVAAAEGYRRLVLGAWGCGV
                     FRNDPVQVAAAFGALLVGDGRFGAHFEQVVFGILDRTPDSPVRAAFTRTFGAGER"
     gene            3600..4949
                     /gene="egtA"
                     /locus_tag="B083_RS0118390"
     CDS             3600..4949
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0052699 - ergothioneine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="egtA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487450.1"
                     /locus_tag="B083_RS0118390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ergothioneine biosynthesis glutamate--cysteine
                     ligase EgtA"
                     /protein_id="WP_028417990.1"
                     /transl_table=11
                     /translation="MSPDTPGGPGPRPESSPLDEGTAQDLLRGICFKTGPPRIVGVELE
                     WLIHDLEHPTVPVAQERLDGAVAALRELPLSAALTFEPGGQLELSSQPAGSLMECVETT
                     AADLAAVRGSLGRAGLAPVGYGVDPWQTPHRRLREPRYDAMEAALDRAGPAGRAMMCTS
                     ASVQVCLDAGEEEPGPRGYGRRWQLTHLLGAVLVAAFANSPFRQGRRTGWKSTRQALWA
                     DLDPVRTLAPGGGLPPREAWAAHVLDTTVMCVRREDGPWDVPEGLTFREWIRTGAPRPP
                     LRADLDYHITTLFPPVRPRGHLELRMIDAQSGPDGWLVPLAVATALFDDPEAAETVYRA
                     VKPLAESAGSAAAPRNALWTTAAREGLADPELRAVAVLCFETALDALDRMGVSTAVRDT
                     VADFHDRYVARGRCPADDLLRPGALAEPVLLSGATRAPTAPSSPGRVASA"
     misc_feature    3675..3677
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4946..6313
                     /gene="egtB"
                     /locus_tag="B083_RS0118395"
     CDS             4946..6313
                     /GO_process="GO:0052699 - ergothioneine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="egtB"
                     /gene_functions="other (smcogs) SMCOG1226: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612915.1"
                     /locus_tag="B083_RS0118395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ergothioneine biosynthesis protein EgtB"
                     /protein_id="WP_028417991.1"
                     /transl_table=11
                     /translation="MTDDRTPSAVAADGFPTGSGGHDPEALRQRALDALLTARARTTVL
                     TDSVDEGELTAQHSPLMSPLVWDLAHIGNQEEQWLLRAVGGREALRPEIDGLYDAFEHP
                     RAARPSLPLLAPAEARTYASDVRGRALDILEAAPLHEGGRPLERAGFAFGMIAQHEQQH
                     DETMLITHQLRSGPVALTAPAPPDPTDTVSLPAEVLVPGGPFTMGTSAEPWALDNERPA
                     HRREVAAFHLDTAPVTCGAYRRFMADGGYTDPRWWAPEGWDMVREHALDAPLFWHRDGG
                     QWLRRRFGVTESVPDDEPVLHVSWYEADAYARWAGRRLPTEAEWEKAARHDPATGRSLR
                     YPWGDTDPTPGQANLGQRHLRPARAGAYPAGRAPSGAGQLIGDVWEWTSSDFLPYPGFV
                     AFPYREYSEVFFGPGHKVLRGGSFAVDQVACRGTFRNWDLPVRRQIFSGFRTARDA"
     gene            6313..7068
                     /gene="egtC"
                     /locus_tag="B083_RS0118400"
     CDS             6313..7068
                     /GO_process="GO:0052699 - ergothioneine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="egtC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007451478.1"
                     /locus_tag="B083_RS0118400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ergothioneine biosynthesis protein EgtC"
                     /protein_id="WP_028417992.1"
                     /transl_table=11
                     /translation="MCRHIAYVGDPVALGSVLSAPPHSLVRQSWAPRRQRHGTVNADGF
                     GVGWYADGDPVPGRYRRQGPVWHDETFTDLARVVRTTAMLAAVRDATEPGADGEAAAAP
                     YTSGRLLFSHNGAVPGWPGSLAGPAAALPARELLSLAARNDSALVWALVLHRVAAGDDL
                     PGAVAETVREVAEAAPGARLNLLVTDGTSIVATAWGDTLWHLHDPGRSTAVASEPYDDD
                     PRWREVPDRTLLVATAADVTPTPLKEPAA"
     gene            7065..8027
                     /gene="egtD"
                     /locus_tag="B083_RS0118405"
     CDS             7065..8027
                     /EC_number="2.1.1.44"
                     /GO_function="GO:0030745 - dimethylhistidine
                     N-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0052699 - ergothioneine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="egtD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964576.1"
                     /locus_tag="B083_RS0118405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L-histidine N(alpha)-methyltransferase"
                     /protein_id="WP_028417993.1"
                     /transl_table=11
                     /translation="MSPFLLTRTLPEDATDAALRADVLSGLTRHPKTLPPKWFYDARGS
                     ELFEEITRLPEYYPTRAEREILEDRSEEIAAVSGARTVIELGSGSSEKTRHLLRALTGL
                     ESYVPVDVSESALTGAAESLLVDHPGLSVHALIADFTGGLALPGTPGPRLVAFLGGTIG
                     NLLPEERAGFLHSVRSLLSPGDTLLLGTDLVKDEETLVAAYDDAAGVTAAFNKNVLSVV
                     NRELGADFPLDAFDHVAVWNPEQRWIEMRLRARRALKVKIRELDLVVPFEAGEEVRTEV
                     SAKFRPEDVREELAAAGLRLAQWWTDGEGRFALSLATAV"
     gene            complement(<8243..9100)
                     /locus_tag="B083_RS0118410"
                     /pseudo=""
     CDS             complement(<8243..9100)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612912.1"
                     /locus_tag="B083_RS0118410"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="lysophospholipid acyltransferase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSTSRTEDRPAPRPAGTSAWLPVAPCAPVSCARHTGAARPPLRAA
                     LRLLAGCGWVLLGVVCAAPVRPLPRAPRTRLLRYWARGIPRAFGVRVTVRGHPDVRGDG
                     GELVVANHLSWLDVPLVAAVLPGRMLAKTEVRDWPLLGRLAGFGSTLFIDRDRLRALPA
                     AVASVATALRSGSRVVVFPEGSTWCGRGRGGAFRPAVFQAAIDAEVSVRPVRITYGTGG
                     AGAAAFVGDDPLTASLWRVVRAAGLTAEVHVLAAIPARAYAPVSEHGEPGRRELARAAR
                     AAVLG"
     gene            complement(9097..9927)
                     /locus_tag="B083_RS0118415"
     CDS             complement(9097..9927)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487445.1"
                     /locus_tag="B083_RS0118415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acyltransferase"
                     /protein_id="WP_028417995.1"
                     /transl_table=11
                     /translation="MTVLPTAPPAAPPTRPVPPAPAAAAPRSPEPAAAYRVSLATGPED
                     VRAAQRLRHQVFAGELGARLEGPEPGLDVDAFDAYCDHLLVRETATDQVVATYRLLPPD
                     RARMAGRLYAESEFDLGRLAPIRDDLVEVGRSCVHPAHRDGAVIALVWAGLARYMQRSG
                     HTWLAGCCSLPLADGGTLAARSWNTVRTAHLAPEEHWVTPHRLWDAAAHPDAGNGSRAD
                     LPPLLRGYLRLGAWVCGAPAYDPEFNVADLYVLLSLRRTDPRYLRHFLSLVPQA"
     gene            complement(10243..11496)
                     /locus_tag="B083_RS0118420"
     CDS             complement(10243..11496)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612910.1"
                     /locus_tag="B083_RS0118420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_028417996.1"
                     /transl_table=11
                     /translation="MKNRILVGAVALVSSVTLSGCGYFSGSGGGDRTVTVWLMKDSVSQ
                     GFLEKFTSTYEKENPSVKLDFKIQEWSGIGPKVLAALESDDAPDVIEVGNTQVAQYAES
                     GNLRDLTLESMRDLGSEDWLPGLAQPGQISGVQYGIPWYAANRVVIYNKDIFKAAGIDD
                     APKTRAEWIEDTGKLNTQGNQGIYLAGQNWYVLAGFIWDEGGELAEGGGGDWRGALDTP
                     EALAGMNFYKELQALGDGPMDSDEEKPPQNDVFAKGNVAQIISLPGSAALIEQQNPELK
                     GKLGYFPIPGKSAKSPGSVFTGGSDLIVPKKADQRSAGIAVVKALASEKWQTELARTMS
                     YVPNKPSLAHVVEGEEGTAAMAEGASQGRATPNSSQWAKVEAENPIKPYMTAVLTGGDP
                     EQEAKKASERITAMLAGS"
     misc_feature    11500..11514
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    11585..11600
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.07"
                     /tool="antismash"
     gene            11701..11916
                     /locus_tag="B083_RS0118425"
     CDS             11701..11916
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766825.1"
                     /locus_tag="B083_RS0118425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dodecin"
                     /protein_id="WP_018487443.1"
                     /transl_table=11
                     /translation="MPNHTYRVTEIVGTSEEGVDAAIRNGIARAAETLHNLDWFEINQV
                     RGHIEDGRIAHYQVGLKVGFRLDENP"
     gene            complement(11939..12427)
                     /locus_tag="B083_RS0118430"
     CDS             complement(11939..12427)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766824.1"
                     /locus_tag="B083_RS0118430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidase"
                     /protein_id="WP_028417997.1"
                     /transl_table=11
                     /translation="MNDDARPLAVFDLDGTLADTAHRQHFLEGPKRDWAGFFAAAPADP
                     PLADGVALVRASAAECEIVYLTGRPERCRRDTVEWLDRQGLPGGQLFMRRNDDRRPARR
                     TKLDILRRLGRSREVRMLVDDDELVCAAAEVAGFPVVRARWSDPSQALKDAQERDGRT"
     gene            12736..12987
                     /locus_tag="B083_RS0118435"
     CDS             12736..12987
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009: mbtH-like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487441.1"
                     /locus_tag="B083_RS0118435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MbtH family NRPS accessory protein"
                     /protein_id="WP_028417998.1"
                     /transl_table=11
                     /translation="MSDHTESVYRVVLNDEEQYSIWQAERELPAGWRAEGTQGSKEECL
                     DHIGRVWTDMRPASLRRRMEGEAAGAAAGRAGRQSLPV"
     gene            13020..14171
                     /gene="sbnA"
                     /locus_tag="B083_RS0118440"
     CDS             13020..14171
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487440.1"
                     /locus_tag="B083_RS0118440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_028417999.1"
                     /sec_met_domain="PALP (E-value: 9.8e-56, bitscore: 183.8,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSVSQPRYRSALVAQAAGPADEEALPHDTTQPSGPASAGYGPGR
                     AGALSAVGGTPLVELTRLVPGARFRVWAKLESVSTGGSIKDRSAYAMLSHAVATGAVVP
                     GSGTVVESSSGNLGVGMAQACRAMDLRFICVVDPRTNPQNIAIMRALGADVHTVTEGDP
                     VTGEFQPVRIARVRELVDALPGAYWPNQYANPRNSWAHRITMAEIVEDLGTAPDYLFCT
                     ISSSGTLRGCGDLIRDRGLPTRVVTVDAEGSAIFRPPTGRRLIPGHGAAVRPPLYRSGL
                     ADEVVHVSDLDSLVGCRRLALREGLLLGGSSGAVATALERTGDRIPDGATCVLMMPDRG
                     ERYLNTIYDDGWVERQFGEVSHLWKDEVADVAENSGMTGVAGC"
     gene            14165..15187
                     /gene="sbnB"
                     /locus_tag="B083_RS0118445"
     CDS             14165..15187
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766821.1"
                     /locus_tag="B083_RS0118445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-diaminopropionate biosynthesis protein SbnB"
                     /protein_id="WP_028418000.1"
                     /transl_table=11
                     /translation="MLTIGNGDVRRLLDGREREVLNAVREAYLLHAAEDTSLPHSVFLR
                     FPDDPGNRIIGLPAYLGGAEPLAGMKWIASFPGNVAEGLERASAAIIVNSMRTGRPVAL
                     VEGSTISARRTAASAALAAAALPSGDGRETGVSLIGCGVINFEVLRFLLVVRPEITDIT
                     VHDLDPRRAADFRDRCSAELAGDGRVVRVAESAGAALSAHRLVSLATTATVPHLDLDAC
                     LPGTLVLHVSLRDVTVEGVLDAVNVVDDPDHVCRAATSVHLAETRVGSRSFIDTTLGEL
                     LRDAEPGPRDPARTTLFSPFGLGVLDLALAGLVLREARAAGVGQEISGFLPESRVAETV
                     "
     gene            15469..16089
                     /locus_tag="B083_RS0118450"
     CDS             15469..16089
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580244.1"
                     /locus_tag="B083_RS0118450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_026237416.1"
                     /transl_table=11
                     /translation="MRNTVRVSVVAEDPVLEAGTLSALASSPEVLPAVGDELPDVTVVV
                     VDRVADPVLDLLRRTRAADHRPEVVLVATELGPPEALHAIATGARGLLRRRETSGPRLA
                     HAVLAAASGDCTVPPDLLDGLLEQRTEDAGAGVADAWGAAGLSERERAVLRLVAEGHET
                     SEIAGRLSYSVRTVTTVMHNVTQRFRLRNRAHAVAYALRAGLL"
     gene            16086..16781
                     /locus_tag="B083_RS0118455"
     CDS             16086..16781
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487437.1"
                     /locus_tag="B083_RS0118455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_078562611.1"
                     /transl_table=11
                     /translation="MSPARALAGAAAPHRAATDRTAVRVHVRAADDDLRSSWHRRLTGA
                     GIPLVEGGRPDPDLVVLAAGRTVDEAVASCPAPEAGGTNRHGVLVAAQSVSPDGVLRAV
                     RAGARTILRTTDATPEQLVAAVHSAHHGDGRLPYGVLVRLLGASQQSGPEPAAALPDAP
                     RTARTAPLTPRQTAVLTLVAEGHGNAVIAQALSCSEHTVKNVIYELMARLQVRNRAHAV
                     ARAVRAGLI"
     gene            complement(16861..17277)
                     /gene="panD"
                     /locus_tag="B083_RS0118460"
     CDS             complement(16861..17277)
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513060.1"
                     /locus_tag="B083_RS0118460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_028418002.1"
                     /transl_table=11
                     /translation="MFRTMFKSKIHRATVTQADLHYVGSLTIDEDLMDAADLLPGEQVQ
                     IVDITNGARLETYVITGERGTGIIGINGAAARLVQPGDLVIIISYASVPDAEAKALVPS
                     VVHVDQHNRQVAPTGSDLAEPAPGSGTVRGDLVH"
     gene            complement(17329..18717)
                     /locus_tag="B083_RS01000000133695"
     CDS             complement(17329..18717)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152228.1"
                     /locus_tag="B083_RS01000000133695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_050451398.1"
                     /transl_table=11
                     /translation="MSRVAEHAGAAPAPPPLRRNRDFLLLWSGSAVAIIGSTASTVAYP
                     LLVLAVTGSPSAAGLVGFVVLLPALVFQLPAGILVDSWNRKRVMMWCDGLRAAGAASVV
                     LALLLGELRLAHVMVVGFVEGTLTVLNGLASTAAVPNVVHPSQLSAALAGNEARGRAAT
                     MIGTPLGGILFGVGRAVPFVLETFAYLVSLATLLGIRKDFQTARPGERAGAGPAGGAAG
                     ESRRTRVRRQAGRMAEGLTWLWRQPLLRTTALLVAGSNLLFRALFLLMIVLLAEEGAGP
                     AAIGVLVGVAGGCGMLGALVAGRIGRTLRMNSLVIGANWAWALLMCVLAFGGGLWPAAI
                     AYTAMWFVGPIWNVAVGTYQLAVTPDGLRGRVLSASSLLANGALSLGALAGGLLLDGFG
                     VRAAAAVLAGWMVLMALAATFSRPVRLATMTAISAPAEPVPAEAPAPAEPRRTPAGASP
                     DAPH"
     misc_feature    complement(18805..18820)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            19015..19932
                     /locus_tag="B083_RS0118470"
     CDS             19015..19932
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (13-293). E-value: 4.5e-48. Score:
                     156.2. Matches aSDomain:
                     nrpspksdomains_B083_RS0118470_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487434.1"
                     /locus_tag="B083_RS0118470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_028418003.1"
                     /sec_met_domain="TauD (E-value: 2.8e-47, bitscore: 156.2,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAPGGSAAERLADARPEIRARLREHGAVLLRGFGDDGVDGFER
                     TVRAIGGEPLTYAERSSPRSTIKGQVYTSTDYPPSEEIFLHNENSYQATWPLTLFFLCV
                     TPPDTLGSTPLADTRRVLAAIDPQVREEFAARGWMVVRNFTDGFGVPWQHAFNTEDRAE
                     VEAYCARNGVTAEWTPGGLRTRARREAVHRHPVTGERVWFNHLTFFHVTTLGPDLCGAL
                     REMYDEADLPTNTYYGDGAPVPDEVVAHLRDCYRAEQRRFDWQQGDVLVVDNMLAAHAR
                     EPFTGPRKIAVAMAEPSSGPVEQG"
     aSDomain        19054..19893
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118470_TauD.1"
                     /evalue="4.50E-48"
                     /label="B083_RS0118470_TauD.1"
                     /locus_tag="B083_RS0118470"
                     /protein_end="293"
                     /protein_start="13"
                     /score="156.2"
                     /tool="antismash"
                     /translation="ADARPEIRARLREHGAVLLRGFGDDGVDGFERTVRAIGGEPLTYA
                     ERSSPRSTIKGQVYTSTDYPPSEEIFLHNENSYQATWPLTLFFLCVTPPDTLGSTPLAD
                     TRRVLAAIDPQVREEFAARGWMVVRNFTDGFGVPWQHAFNTEDRAEVEAYCARNGVTAE
                     WTPGGLRTRARREAVHRHPVTGERVWFNHLTFFHVTTLGPDLCGALREMYDEADLPTNT
                     YYGDGAPVPDEVVAHLRDCYRAEQRRFDWQQGDVLVVDNMLAAHAREPFTGPRKIAVA"
     gene            20001..26477
                     /locus_tag="B083_RS0118475"
     CDS             20001..26477
                     /NRPS_PKS="Domain: Condensation_LCL (7-308). E-value:
                     2e-96. Score: 314.5. Matches aSDomain:
                     nrpspksdomains_B083_RS0118475_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (479-879). E-value:
                     2.1e-105. Score: 344.6. Matches aSDomain:
                     nrpspksdomains_B083_RS0118475_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (995-1064). E-value: 1.4e-20. Score:
                     65.2. Matches aSDomain:
                     nrpspksdomains_B083_RS0118475_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1088-1384). E-value:
                     9.2e-101. Score: 328.7. Matches aSDomain:
                     nrpspksdomains_B083_RS0118475_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1559-1958). E-value:
                     2.1e-100. Score: 328.1. Matches aSDomain:
                     nrpspksdomains_B083_RS0118475_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2066-2134). E-value: 3.4e-27.
                     Score: 86.4. Matches aSDomain:
                     nrpspksdomains_B083_RS0118475_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1209: polyketide synthase associated protein papA3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487433.1"
                     /locus_tag="B083_RS0118475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_028418004.1"
                     /sec_met_domain="Condensation (E-value: 1.5e-68, bitscore:
                     225.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-115, bitscore:
                     381.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.7e-18, bitscore:
                     60.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVDGGYPLSFAQEQLWLLDQLRSGDAAEYLMHETFRIRGPLDT
                     EALNAALTETAARHEVLRTRYAEEDGVGVQVIDEPEPVKPESVDLGDVPDEQREQGLRE
                     FRASWAATPLDIRREHPWRVAVVRLAPEDWALLLTFHHIAFDGWSWGLLADELRASYAA
                     FASGGTPAAEELELQYADYAEWQREWWTAQPELMDRQLGYWRDRLTGTAALDLPTDRPR
                     PARWDATGGTVAFTVPAPLAAGFSALAKEQGTTLFMAGLAAYQLLLGRYSGAEDIAVGV
                     SLANRDDARLERLIGLFLNTVVVRTDLGGAPDFRELLSRVKSTTLDAYSHQEVPFERVV
                     AALAPERDPGRNPVFQAGFALHNAHRRPFALTGLEVTRVTGGAHSSAFDLSLHLTERPD
                     GTIGGEFIYPTALFDRDRMERMAENFLHLLGQAVASPGTPVDRLELTAPAERAALTAWG
                     QGATRPAAEDRSGRGLVAMVLDRAAATPYATAVAYDGGSVDYAGLAGRVTLLAARLREE
                     GVRPGTPVAVALHRGPELVTAILAVLAVGGVHVPLAPDLPDVRREFLLSDSGAALVLTE
                     EALRDRFGADVPVRALDAEWAGTGPAASPAAFPHPAGPDEAACVVYTSGSTGTPKGVVV
                     THGGLRNRVLWSVEAYAMTAADRLLQKTTIGFDASLWEFLSPLVSGGTVVMAPADAHRD
                     PSVMAAAMDRHRVTLLQLVPSVLRLLVQEPALSRCTALRLVSSAGEPLPARLCERLREA
                     VPGVEVSNTYGPTECSIDSTAHRYTGEGLPGSGTVAIGAPLTGVGVSVVDRADLLVPVG
                     VPGELCVRGAGLARGYLGRPGQTAERFGVDPYATVPGGRWYRTGDLVRWRADGTLEFLG
                     RSDDQVKIHGVRVEPAEIEALLLAHPSATASAVVARPGAHGQLELTAYAVPAAGSDPAG
                     LRAELLAHLAARLPAAVVPSRLVLLDALPLTASGKVDRGALPGPEDGMAPPAADGPERA
                     APRTATEQAVVAAMASVLEIPEPGPDDDFFGLGGHSLLAIRLVLGLRRAFGIEMTVADL
                     FADRTAAALAARIDRAAGTSEEEEPGQAPGGIVPVARDGVLPLSFGQQRMWFLDRLEPG
                     SREYLIPLALRLRGPLDTGAFRRALEEVARVHEVLRTRYADHDGSPVQLIDPPGPVAYR
                     EVDLSGTEDGPVRARELLEEVLTVPFDLAAEHPLRVTVIRAAAEDHWVALAAHHIAFDA
                     WSTKVFLRDLDTAYTALAAGRETPLRPGPVQYADFAAWQRAQEETPETGRQLRYWVERL
                     GGLTPVELPSDRPRGSGRDAAGDTVIVDVPDALGRAVTELGERSGATPFMTLLGAFQVL
                     LHHYTGRTDIAVGVPVAARTREETEGLLGLFVNSLVIRTDLGGDPAFTGLLEQVKRVCL
                     EAFAHQDVPFERLVDELATDRDLSRNPLFQVMFEHQHMGGLTSTLGGLAAEPLNAGPQT
                     AKFDLTLTVKERPDGRMHCWFEYASALFDRSTVERMATHYLRLLESVTAAPDTAVAGLD
                     LMSDAERRQLLDVWPDPDAARLPEIVPEDESGLTVPELFVRQAARTPDATALVFGGEEL
                     DYAALEARSARFARRLRALGAGPETAVASCQERGIDAVVTLLGVLRAGAVYVPLDPRHP
                     RQRLLRTVEDAGARFLVTTSGHAETLTGAGHQVLTVDALVAEGAEGELPDVPADPENLA
                     YVIYTSGSTGRPKGVMIDHRAYAHHCRVAADAYGIGPGERVVQLSSLTFDVSMEQIAAP
                     LLTGAAVVIADPLFWSPAELPARLAEHGVTVMETTPAYYREAMNYDTSVLTGLKLINLS
                     SDVVTVADARQWAASGLPGRFVCCYGPTEATVTCLLHTGPAGQGGERDTASMPLGRPFA
                     GTRAYVLDAGQRPVPIGVPGELCVGGVRLARGYHGRPELTAAQFVPDPFGGAGERLYRT
                     GDLVRYRPDGTLEFLGRIDQQVKIRGLRIELGEIEAALTGHPGVGASAVTAPEIAPGDR
                     RLAAYVTGLDGAPAPDPETLREHLREGLPDYMVPALWTVLDSLPMTASQKIDRKALPAP
                     ATTLERAYVAPRDPVEEAVAAIWAEALGVDRVGAEDDFFALGGHSLLATRVLARLREAF
                     AVELPLRRLFEHTTVTALAAAVTEAVEAAIAQLSDAEVAELLNPEGAR"
     aSDomain        20022..20924
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118475_Condensation_LCL.
                     1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.00E-96"
                     /label="B083_RS0118475_Condensation_LCL.1"
                     /locus_tag="B083_RS0118475"
                     /protein_end="308"
                     /protein_start="7"
                     /score="314.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAFDG"
                     /tool="antismash"
                     /translation="YPLSFAQEQLWLLDQLRSGDAAEYLMHETFRIRGPLDTEALNAAL
                     TETAARHEVLRTRYAEEDGVGVQVIDEPEPVKPESVDLGDVPDEQREQGLREFRASWAA
                     TPLDIRREHPWRVAVVRLAPEDWALLLTFHHIAFDGWSWGLLADELRASYAAFASGGTP
                     AAEELELQYADYAEWQREWWTAQPELMDRQLGYWRDRLTGTAALDLPTDRPRPARWDAT
                     GGTVAFTVPAPLAAGFSALAKEQGTTLFMAGLAAYQLLLGRYSGAEDIAVGVSLANRDD
                     ARLERLIGLFLNTVVVRTDL"
     aSModule        20022..23192
                     /complete
                     /domains="nrpspksdomains_B083_RS0118475_Condensation_LCL.1"
                     /domains="nrpspksdomains_B083_RS0118475_AMP-binding.1"
                     /domains="nrpspksdomains_B083_RS0118475_PCP.1"
                     /locus_tags="B083_RS0118475"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20031..20063
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0001"
                     /evalue="1.70E-01"
                     /label="C1_LCL_004-017"
                     /locus_tag="B083_RS0118475"
                     /protein_end="21"
                     /protein_start="10"
                     /score="5.3"
                     /tool="antismash"
                     /translation="SFAQEQLWLLD"
     CDS_motif       20091..20198
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0002"
                     /evalue="3.60E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="B083_RS0118475"
                     /protein_end="66"
                     /protein_start="30"
                     /score="45.1"
                     /tool="antismash"
                     /translation="YLMHETFRIRGPLDTEALNAALTETAARHEVLRTRY"
     CDS_motif       20418..20483
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0003"
                     /evalue="1.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="B083_RS0118475"
                     /protein_end="161"
                     /protein_start="139"
                     /score="30.2"
                     /tool="antismash"
                     /translation="FHHIAFDGWSWGLLADELRASY"
     CDS_motif       20532..20567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0004"
                     /evalue="3.40E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B083_RS0118475"
                     /protein_end="189"
                     /protein_start="177"
                     /score="13.3"
                     /tool="antismash"
                     /translation="QYADYAEWQREW"
     CDS_motif       20826..20915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0005"
                     /evalue="2.40E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="B083_RS0118475"
                     /protein_end="305"
                     /protein_start="275"
                     /score="36.0"
                     /tool="antismash"
                     /translation="DIAVGVSLANRDDARLERLIGLFLNTVVVR"
     CDS_motif       20967..21083
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0006"
                     /evalue="2.60E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B083_RS0118475"
                     /protein_end="361"
                     /protein_start="322"
                     /score="68.1"
                     /tool="antismash"
                     /translation="STTLDAYSHQEVPFERVVAALAPERDPGRNPVFQAGFAL"
     aSDomain        21438..22637
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118475_AMP-binding.1"
                     /evalue="2.10E-105"
                     /label="B083_RS0118475_AMP-binding.1"
                     /locus_tag="B083_RS0118475"
                     /protein_end="879"
                     /protein_start="479"
                     /score="344.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DRAAATPYATAVAYDGGSVDYAGLAGRVTLLAARLREEGVRPGTP
                     VAVALHRGPELVTAILAVLAVGGVHVPLAPDLPDVRREFLLSDSGAALVLTEEALRDRF
                     GADVPVRALDAEWAGTGPAASPAAFPHPAGPDEAACVVYTSGSTGTPKGVVVTHGGLRN
                     RVLWSVEAYAMTAADRLLQKTTIGFDASLWEFLSPLVSGGTVVMAPADAHRDPSVMAAA
                     MDRHRVTLLQLVPSVLRLLVQEPALSRCTALRLVSSAGEPLPARLCERLREAVPGVEVS
                     NTYGPTECSIDSTAHRYTGEGLPGSGTVAIGAPLTGVGVSVVDRADLLVPVGVPGELCV
                     RGAGLARGYLGRPGQTAERFGVDPYATVPGGRWYRTGDLVRWRADGTLEFLGRSDDQVK
                     I"
     CDS_motif       21618..21656
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0007"
                     /evalue="6.10E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="B083_RS0118475"
                     /protein_end="552"
                     /protein_start="539"
                     /score="4.3"
                     /tool="antismash"
                     /translation="LAVLAVGGVHVPL"
     CDS_motif       21852..21911
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0008"
                     /evalue="8.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="B083_RS0118475"
                     /protein_end="637"
                     /protein_start="617"
                     /score="30.6"
                     /tool="antismash"
                     /translation="ACVVYTSGSTGTPKGVVVTH"
     CDS_motif       22287..22310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0009"
                     /evalue="6.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="B083_RS0118475"
                     /protein_end="770"
                     /protein_start="762"
                     /score="6.4"
                     /tool="antismash"
                     /translation="YGPTECSI"
     CDS_motif       22428..22517
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0010"
                     /evalue="2.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="B083_RS0118475"
                     /protein_end="839"
                     /protein_start="809"
                     /score="51.8"
                     /tool="antismash"
                     /translation="PVGVPGELCVRGAGLARGYLGRPGQTAERF"
     CDS_motif       22605..22670
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0011"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="B083_RS0118475"
                     /protein_end="890"
                     /protein_start="868"
                     /score="33.3"
                     /tool="antismash"
                     /translation="FLGRSDDQVKIHGVRVEPAEIE"
     aSDomain        22986..23192
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118475_PCP.1"
                     /evalue="1.40E-20"
                     /label="B083_RS0118475_PCP.1"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1064"
                     /protein_start="995"
                     /score="65.2"
                     /tool="antismash"
                     /translation="EQAVVAAMASVLEIPEPGPDDDFFGLGGHSLLAIRLVLGLRRAFG
                     IEMTVADLFADRTAAALAARIDRA"
     aSDomain        23265..24152
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118475_Condensation_LCL.
                     2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.20E-101"
                     /label="B083_RS0118475_Condensation_LCL.2"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1384"
                     /protein_start="1088"
                     /score="328.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAFDA"
                     /tool="antismash"
                     /translation="LPLSFGQQRMWFLDRLEPGSREYLIPLALRLRGPLDTGAFRRALE
                     EVARVHEVLRTRYADHDGSPVQLIDPPGPVAYREVDLSGTEDGPVRARELLEEVLTVPF
                     DLAAEHPLRVTVIRAAAEDHWVALAAHHIAFDAWSTKVFLRDLDTAYTALAAGRETPLR
                     PGPVQYADFAAWQRAQEETPETGRQLRYWVERLGGLTPVELPSDRPRGSGRDAAGDTVI
                     VDVPDALGRAVTELGERSGATPFMTLLGAFQVLLHHYTGRTDIAVGVPVAARTREETEG
                     LLGLFVNSLVIRTDL"
     aSModule        23265..26402
                     /complete
                     /domains="nrpspksdomains_B083_RS0118475_Condensation_LCL.2"
                     /domains="nrpspksdomains_B083_RS0118475_AMP-binding.2"
                     /domains="nrpspksdomains_B083_RS0118475_PCP.2"
                     /locus_tags="B083_RS0118475"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       23274..23306
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0012"
                     /evalue="7.10E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1102"
                     /protein_start="1091"
                     /score="9.1"
                     /tool="antismash"
                     /translation="SFGQQRMWFLD"
     CDS_motif       23331..23438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0013"
                     /evalue="2.40E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1146"
                     /protein_start="1110"
                     /score="45.7"
                     /tool="antismash"
                     /translation="YLIPLALRLRGPLDTGAFRRALEEVARVHEVLRTRY"
     CDS_motif       23655..23717
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0014"
                     /evalue="2.00E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1239"
                     /protein_start="1218"
                     /score="26.8"
                     /tool="antismash"
                     /translation="HHIAFDAWSTKVFLRDLDTAY"
     CDS_motif       23766..23798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0015"
                     /evalue="1.90E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1266"
                     /protein_start="1255"
                     /score="14.1"
                     /tool="antismash"
                     /translation="QYADFAAWQRA"
     CDS_motif       24054..24143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0016"
                     /evalue="5.60E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1381"
                     /protein_start="1351"
                     /score="44.4"
                     /tool="antismash"
                     /translation="DIAVGVPVAARTREETEGLLGLFVNSLVIR"
     CDS_motif       24192..24308
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0017"
                     /evalue="9.80E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1436"
                     /protein_start="1397"
                     /score="75.9"
                     /tool="antismash"
                     /translation="KRVCLEAFAHQDVPFERLVDELATDRDLSRNPLFQVMFE"
     aSDomain        24678..25874
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118475_AMP-binding.2"
                     /evalue="2.10E-100"
                     /label="B083_RS0118475_AMP-binding.2"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1958"
                     /protein_start="1559"
                     /score="328.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="VRQAARTPDATALVFGGEELDYAALEARSARFARRLRALGAGPET
                     AVASCQERGIDAVVTLLGVLRAGAVYVPLDPRHPRQRLLRTVEDAGARFLVTTSGHAET
                     LTGAGHQVLTVDALVAEGAEGELPDVPADPENLAYVIYTSGSTGRPKGVMIDHRAYAHH
                     CRVAADAYGIGPGERVVQLSSLTFDVSMEQIAAPLLTGAAVVIADPLFWSPAELPARLA
                     EHGVTVMETTPAYYREAMNYDTSVLTGLKLINLSSDVVTVADARQWAASGLPGRFVCCY
                     GPTEATVTCLLHTGPAGQGGERDTASMPLGRPFAGTRAYVLDAGQRPVPIGVPGELCVG
                     GVRLARGYHGRPELTAAQFVPDPFGGAGERLYRTGDLVRYRPDGTLEFLGRIDQQVKIR
                     "
     CDS_motif       24861..24902
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0018"
                     /evalue="6.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1634"
                     /protein_start="1620"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LGVLRAGAVYVPLD"
     CDS_motif       25089..25148
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0019"
                     /evalue="5.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1716"
                     /protein_start="1696"
                     /score="34.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVMIDH"
     CDS_motif       25518..25547
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0020"
                     /evalue="4.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1849"
                     /protein_start="1839"
                     /score="6.9"
                     /tool="antismash"
                     /translation="YGPTEATVTC"
     CDS_motif       25665..25754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0021"
                     /evalue="3.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1918"
                     /protein_start="1888"
                     /score="51.3"
                     /tool="antismash"
                     /translation="PIGVPGELCVGGVRLARGYHGRPELTAAQF"
     CDS_motif       25839..25904
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118475_0022"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="B083_RS0118475"
                     /protein_end="1968"
                     /protein_start="1946"
                     /score="35.6"
                     /tool="antismash"
                     /translation="FLGRIDQQVKIRGLRIELGEIE"
     aSDomain        26199..26402
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118475_PCP.2"
                     /evalue="3.40E-27"
                     /label="B083_RS0118475_PCP.2"
                     /locus_tag="B083_RS0118475"
                     /protein_end="2134"
                     /protein_start="2066"
                     /score="86.4"
                     /tool="antismash"
                     /translation="EEAVAAIWAEALGVDRVGAEDDFFALGGHSLLATRVLARLREAFA
                     VELPLRRLFEHTTVTALAAAVTE"
     gene            26474..33697
                     /locus_tag="B083_RS0118480"
     CDS             26474..33697
                     /NRPS_PKS="Domain: Condensation_LCL (39-338). E-value:
                     1.7e-101. Score: 331.1. Matches aSDomain:
                     nrpspksdomains_B083_RS0118480_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (508-903). E-value:
                     3.7e-110. Score: 360.2. Matches aSDomain:
                     nrpspksdomains_B083_RS0118480_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1011-1079). E-value: 1.5e-18.
                     Score: 58.8. Matches aSDomain:
                     nrpspksdomains_B083_RS0118480_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1108-1408). E-value:
                     4.9e-57. Score: 185.3. Matches aSDomain:
                     nrpspksdomains_B083_RS0118480_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1560-1949). E-value:
                     5.4e-112. Score: 366.3. Matches aSDomain:
                     nrpspksdomains_B083_RS0118480_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2056-2124). E-value: 6.8e-23.
                     Score: 72.7. Matches aSDomain:
                     nrpspksdomains_B083_RS0118480_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2145-2403). E-value:
                     1.6e-29. Score: 95.9. Matches aSDomain:
                     nrpspksdomains_B083_RS0118480_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487432.1"
                     /locus_tag="B083_RS0118480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_028418005.1"
                     /sec_met_domain="Condensation (E-value: 8e-69, bitscore:
                     226.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-120, bitscore:
                     395.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-13, bitscore:
                     45.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 6.3e-25, bitscore:
                     83.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHQTLDPADLRARLLRQRLRGTAAPAPSDGIPRAGRGGPLPLSS
                     AQQRLWVLDRLSPGSTTYLMTAALRLRGPLAPEALRGALEALVTRHEVLRTRYEVVDGD
                     PVQIVDAPAPVDLVEEDLTGLDPADRARRLTALGTSGRRPVDLAEGPVFRAVLARCSAE
                     EHALFLTVHHIAADGRSEELMVRELMAHYRRSTAGETHPDPAPPALQYADFAVWQRSRL
                     TEERLRAGLDHWRGRLAGLTPLELPTDRPRPAVRDERGAVAPFTVPAEVAGRLSRLARE
                     RGATPFMAALAAFQVLLGRYAGSTDIAVGTPVSGRDRTETQDMLGLFLNTLVLRTDLSG
                     APGFGEVLNRVREGSLDDYGHQEVPFERLVDALAPERDPSRTPLFGAMFLWDGADGPSS
                     EAHAGGADSLVVERLAVGESTAKFDLTLSVAEQPDGSLSGGLNYATALFDAATAARMAD
                     HFVRLLTAAVAEPDVPVAELELMSPAELEQVVHRWNETDVPFPTGTLHGLFEAQAAATP
                     EAVAVADEDGTLGYGELDRRAEAVADALRARGAGPGTVTGVCLERSRGLLVALLGVLKA
                     GSAYLPLEPDLPAERRRYMLSDSGARVVLTDTGAGPDGVPEEVAVVPLARGGMLPDGAP
                     ALPGGSSGPDDAAYLIYTSGSTGRPKGVLVEHRAIVNRLHWMQREFGLDATDRVLQKTP
                     MGFDVSVWEFFWPVITGATLVMARPGGHRDPAYLARTIAERSITTLHFVPSMLRAFLAG
                     PVPALPSVRRVVCSGEALPGDLVTAAVERLGTAPHNLYGPTEAAVDVTHAPCVPGRRVT
                     IGRPIANTRTYIVDAALRPVPVGVPGELLLGGVQLARGYPGRPALTADRFVPDPFGGEP
                     GGRLYRTGDLARYLPDGTIDYLGRMDHQVKIRGQRIELGEIEAVLHEHPSVSAAAVTVH
                     DGRLVAHLVGHPSPEDGAPDTDAVRTWLRERLPDAMVPGDWTVLDALPLTASGKTDRKA
                     LPAPDRSRESRAGEYTAPRTPVERTIAEELAAALDLDRVGVHDRFFDLGGDSIRAIRAV
                     GALTARGLALSVQHLFTHPTAARLATVATETTGTGQGPELVAPFAQLAPADLERLPDGL
                     ADAYPLGEVQAGMVYELLADPDANTYQNVSSFHFTDDGPFDLPALREAVRRLVDRHEIL
                     RTSFRLSGFSGPLQLVHEKAGAEVGFTDLRELDPAGQRAAIAEFRAAEQRLPFDLERAP
                     LLRYHVHRTGERTWTLTHTECHAILDGWSHHSVIQEIRADYGRIREDADCAVTPPPRAR
                     YADFIALEQRALESSEDRAFWQSRIDGFPRLELPAPTAPAEADGPAHEVRVSWAGLDPE
                     LRALAARTGTSLKTVLYTAHLTLLGLISGQRRFFAGAVCNGRPELPDGDEVRGMYLNTV
                     PFAVDLRAPSWEELLRAVFAEEAAVWPHRRYPLPAMQREWGAGVPLVDVIFGYLDFHVL
                     DQSGSAPEAVTDSSPNEFTFDVWTFPGELRMTCRPGWADRARLETMAAAFVEVLRTMAE
                     RPDSSPASFRATGLTGDAAGAVPRRLPPEVTLPELIGRGADPEAVALVDRGSAVTYGQL
                     EERANRFARLLRARGVRAEDPVAVCLERGAETVVALLGVVKAGGCYVPVDPEYPEERIG
                     YLLSDSGARLLVTRSDLAGRLPGNVPTVLLDIARDELEAQSPTAPETGVSPDNTAYVIY
                     TSGSTGRPKGVQITHRNVVRLVHDENHAAIGPRDTVLVVSPLAFDASAFELWGTLANGG
                     RLAFAPPGTPTTAGIAEVLREHGVTVAFLTTSLFHLMVESCPDALTGLRTLLTGGDVLS
                     AGRVRAALGHGLRVSNMYGPTECTTFATGQHAITLEQTDRPIPIGLPIAHTTALVTDED
                     LVPVPYGVAGELLLGGPGVARGYLGRPELTADRFVPDPTGTWPGGRLYRTGDLVRQDPD
                     GVLHFLGRRDHQVKVRGHRIELGEVEAGLSGLPGVHEAAAAVRPGPDGDKQLVGYIVPE
                     EHSGFDPALLRAALRAKVPGFLVPSAWVRLEELPLNANGKLDRAALPAPDGGTAGEVVA
                     PRTAAERALAEVWAEVLNLEQVGVHDDFFLLGGHSLLILRAIALLRERHGLELTVRAFV
                     EHHTLDAIAAAAERGDYGDTSRTALMWLRAEGDRAPLFCVHPGGGSAHWYQRLLPHLAP
                     DLPVAALEWPGLQSGPGLPVPTASEMAQRYVAEIRAARPHGPYRLLGWCGGSGITAEMA
                     DRLRADGEEVTFVLLDPGLDSHERQGLWEEFRLIESCTAKLEELAAAGPEEDTGALREE
                     ILKLLDHLVDDADPETGIVLPEHNGADVWLPSARIWREVMEMTLTYRHHHVPGTLHLVI
                     SDELARGEHEVALGQSYEEYLSRWRELNSGVEVHRVPGDHFGVMRLPHVTSLASTLASV
                     LD"
     aSDomain        26591..27487
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118480_Condensation_LCL.
                     1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.70E-101"
                     /label="B083_RS0118480_Condensation_LCL.1"
                     /locus_tag="B083_RS0118480"
                     /protein_end="338"
                     /protein_start="39"
                     /score="331.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="PLPLSSAQQRLWVLDRLSPGSTTYLMTAALRLRGPLAPEALRGAL
                     EALVTRHEVLRTRYEVVDGDPVQIVDAPAPVDLVEEDLTGLDPADRARRLTALGTSGRR
                     PVDLAEGPVFRAVLARCSAEEHALFLTVHHIAADGRSEELMVRELMAHYRRSTAGETHP
                     DPAPPALQYADFAVWQRSRLTEERLRAGLDHWRGRLAGLTPLELPTDRPRPAVRDERGA
                     VAPFTVPAEVAGRLSRLARERGATPFMAALAAFQVLLGRYAGSTDIAVGTPVSGRDRTE
                     TQDMLGLFLNTLVLRTDL"
     aSModule        26591..29710
                     /complete
                     /domains="nrpspksdomains_B083_RS0118480_Condensation_LCL.1"
                     /domains="nrpspksdomains_B083_RS0118480_AMP-binding.1"
                     /domains="nrpspksdomains_B083_RS0118480_PCP.1"
                     /locus_tags="B083_RS0118480"
                     /monomer_pairings="Ser -> Ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       26654..26767
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0001"
                     /evalue="1.60E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="B083_RS0118480"
                     /protein_end="98"
                     /protein_start="60"
                     /score="46.3"
                     /tool="antismash"
                     /translation="TTYLMTAALRLRGPLAPEALRGALEALVTRHEVLRTRY"
     CDS_motif       26984..27049
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0002"
                     /evalue="1.80E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="B083_RS0118480"
                     /protein_end="192"
                     /protein_start="170"
                     /score="23.7"
                     /tool="antismash"
                     /translation="VHHIAADGRSEELMVRELMAHY"
     CDS_motif       27101..27139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0003"
                     /evalue="5.20E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="B083_RS0118480"
                     /protein_end="222"
                     /protein_start="209"
                     /score="18.9"
                     /tool="antismash"
                     /translation="QYADFAVWQRSRL"
     CDS_motif       27389..27478
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0004"
                     /evalue="1.70E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="B083_RS0118480"
                     /protein_end="335"
                     /protein_start="305"
                     /score="46.1"
                     /tool="antismash"
                     /translation="DIAVGTPVSGRDRTETQDMLGLFLNTLVLR"
     CDS_motif       27527..27643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0005"
                     /evalue="2.60E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B083_RS0118480"
                     /protein_end="390"
                     /protein_start="351"
                     /score="61.6"
                     /tool="antismash"
                     /translation="REGSLDDYGHQEVPFERLVDALAPERDPSRTPLFGAMFL"
     aSDomain        27998..29182
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118480_AMP-binding.1"
                     /evalue="3.70E-110"
                     /label="B083_RS0118480_AMP-binding.1"
                     /locus_tag="B083_RS0118480"
                     /protein_end="903"
                     /protein_start="508"
                     /score="360.2"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="FEAQAAATPEAVAVADEDGTLGYGELDRRAEAVADALRARGAGPG
                     TVTGVCLERSRGLLVALLGVLKAGSAYLPLEPDLPAERRRYMLSDSGARVVLTDTGAGP
                     DGVPEEVAVVPLARGGMLPDGAPALPGGSSGPDDAAYLIYTSGSTGRPKGVLVEHRAIV
                     NRLHWMQREFGLDATDRVLQKTPMGFDVSVWEFFWPVITGATLVMARPGGHRDPAYLAR
                     TIAERSITTLHFVPSMLRAFLAGPVPALPSVRRVVCSGEALPGDLVTAAVERLGTAPHN
                     LYGPTEAAVDVTHAPCVPGRRVTIGRPIANTRTYIVDAALRPVPVGVPGELLLGGVQLA
                     RGYPGRPALTADRFVPDPFGGEPGGRLYRTGDLARYLPDGTIDYLGRMDHQVKIR"
     CDS_motif       28184..28222
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0006"
                     /evalue="1.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="B083_RS0118480"
                     /protein_end="583"
                     /protein_start="570"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LGVLKAGSAYLPL"
     CDS_motif       28415..28474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0007"
                     /evalue="2.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="B083_RS0118480"
                     /protein_end="667"
                     /protein_start="647"
                     /score="32.1"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGRPKGVLVEH"
     CDS_motif       28844..28867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0008"
                     /evalue="4.50E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="B083_RS0118480"
                     /protein_end="798"
                     /protein_start="790"
                     /score="4.1"
                     /tool="antismash"
                     /translation="YGPTEAAV"
     CDS_motif       28970..29059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0009"
                     /evalue="9.50E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="B083_RS0118480"
                     /protein_end="862"
                     /protein_start="832"
                     /score="46.7"
                     /tool="antismash"
                     /translation="PVGVPGELLLGGVQLARGYPGRPALTADRF"
     CDS_motif       29147..29212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0010"
                     /evalue="8.90E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="B083_RS0118480"
                     /protein_end="913"
                     /protein_start="891"
                     /score="40.0"
                     /tool="antismash"
                     /translation="YLGRMDHQVKIRGQRIELGEIE"
     CDS_motif       29420..29446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0011"
                     /evalue="6.20E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="B083_RS0118480"
                     /protein_end="991"
                     /protein_start="982"
                     /score="3.6"
                     /tool="antismash"
                     /translation="GKTDRKALP"
     aSDomain        29507..29710
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118480_PCP.1"
                     /evalue="1.50E-18"
                     /label="B083_RS0118480_PCP.1"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1079"
                     /protein_start="1011"
                     /score="58.8"
                     /tool="antismash"
                     /translation="ERTIAEELAAALDLDRVGVHDRFFDLGGDSIRAIRAVGALTARGL
                     ALSVQHLFTHPTAARLATVATET"
     aSDomain        29798..30697
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118480_Condensation_DCL.
                     1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.90E-57"
                     /label="B083_RS0118480_Condensation_DCL.1"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1408"
                     /protein_start="1108"
                     /score="185.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: CHAILDG"
                     /tool="antismash"
                     /translation="DAYPLGEVQAGMVYELLADPDANTYQNVSSFHFTDDGPFDLPALR
                     EAVRRLVDRHEILRTSFRLSGFSGPLQLVHEKAGAEVGFTDLRELDPAGQRAAIAEFRA
                     AEQRLPFDLERAPLLRYHVHRTGERTWTLTHTECHAILDGWSHHSVIQEIRADYGRIRE
                     DADCAVTPPPRARYADFIALEQRALESSEDRAFWQSRIDGFPRLELPAPTAPAEADGPA
                     HEVRVSWAGLDPELRALAARTGTSLKTVLYTAHLTLLGLISGQRRFFAGAVCNGRPELP
                     DGDEVRGMYLNTVPFAVDL"
     aSModule        29798..33682
                     /complete
                     /domains="nrpspksdomains_B083_RS0118480_Condensation_DCL.1"
                     /domains="nrpspksdomains_B083_RS0118480_AMP-binding.2"
                     /domains="nrpspksdomains_B083_RS0118480_PCP.2"
                     /domains="nrpspksdomains_B083_RS0118480_Thioesterase.1"
                     /final_module
                     /locus_tags="B083_RS0118480"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       29903..29986
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0012"
                     /evalue="1.70E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1171"
                     /protein_start="1143"
                     /score="39.7"
                     /tool="antismash"
                     /translation="DGPFDLPALREAVRRLVDRHEILRTSFR"
     CDS_motif       30212..30259
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0013"
                     /evalue="6.70E-03"
                     /label="C3_DCL_135-156"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1262"
                     /protein_start="1246"
                     /score="9.2"
                     /tool="antismash"
                     /translation="HAILDGWSHHSVIQEI"
     CDS_motif       30374..30397
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0014"
                     /evalue="4.20E+01"
                     /label="C4_LCL_164-176"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1308"
                     /protein_start="1300"
                     /score="-2.3"
                     /tool="antismash"
                     /translation="DRAFWQSR"
     CDS_motif       30608..30685
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0015"
                     /evalue="3.00E-04"
                     /label="C5_DCL_263-294"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1404"
                     /protein_start="1378"
                     /score="13.3"
                     /tool="antismash"
                     /translation="GAVCNGRPELPDGDEVRGMYLNTVPF"
     aSDomain        31154..32320
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118480_AMP-binding.2"
                     /evalue="5.40E-112"
                     /label="B083_RS0118480_AMP-binding.2"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1949"
                     /protein_start="1560"
                     /score="366.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DPEAVALVDRGSAVTYGQLEERANRFARLLRARGVRAEDPVAVCL
                     ERGAETVVALLGVVKAGGCYVPVDPEYPEERIGYLLSDSGARLLVTRSDLAGRLPGNVP
                     TVLLDIARDELEAQSPTAPETGVSPDNTAYVIYTSGSTGRPKGVQITHRNVVRLVHDEN
                     HAAIGPRDTVLVVSPLAFDASAFELWGTLANGGRLAFAPPGTPTTAGIAEVLREHGVTV
                     AFLTTSLFHLMVESCPDALTGLRTLLTGGDVLSAGRVRAALGHGLRVSNMYGPTECTTF
                     ATGQHAITLEQTDRPIPIGLPIAHTTALVTDEDLVPVPYGVAGELLLGGPGVARGYLGR
                     PELTADRFVPDPTGTWPGGRLYRTGDLVRQDPDGVLHFLGRRDHQVKVR"
     CDS_motif       31319..31360
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0016"
                     /evalue="2.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1629"
                     /protein_start="1615"
                     /score="14.2"
                     /tool="antismash"
                     /translation="LGVVKAGGCYVPVD"
     CDS_motif       31550..31609
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0017"
                     /evalue="2.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1712"
                     /protein_start="1692"
                     /score="32.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVQITH"
     CDS_motif       31970..31993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0018"
                     /evalue="9.30E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1840"
                     /protein_start="1832"
                     /score="6.0"
                     /tool="antismash"
                     /translation="YGPTECTT"
     CDS_motif       32108..32197
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0019"
                     /evalue="3.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1908"
                     /protein_start="1878"
                     /score="51.2"
                     /tool="antismash"
                     /translation="PYGVAGELLLGGPGVARGYLGRPELTADRF"
     CDS_motif       32285..32350
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0020"
                     /evalue="8.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="B083_RS0118480"
                     /protein_end="1959"
                     /protein_start="1937"
                     /score="37.1"
                     /tool="antismash"
                     /translation="FLGRRDHQVKVRGHRIELGEVE"
     CDS_motif       32564..32590
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0021"
                     /evalue="7.50E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="B083_RS0118480"
                     /protein_end="2039"
                     /protein_start="2030"
                     /score="3.4"
                     /tool="antismash"
                     /translation="GKLDRAALP"
     aSDomain        32642..32845
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118480_PCP.2"
                     /evalue="6.80E-23"
                     /label="B083_RS0118480_PCP.2"
                     /locus_tag="B083_RS0118480"
                     /protein_end="2124"
                     /protein_start="2056"
                     /score="72.7"
                     /tool="antismash"
                     /translation="ERALAEVWAEVLNLEQVGVHDDFFLLGGHSLLILRAIALLRERHG
                     LELTVRAFVEHHTLDAIAAAAER"
     CDS_motif       32909..32938
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0022"
                     /evalue="1.90E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="B083_RS0118480"
                     /protein_end="2155"
                     /protein_start="2145"
                     /score="11.2"
                     /tool="antismash"
                     /translation="PLFCVHPGGG"
     aSDomain        32909..33682
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0118480_Thioesterase.1"
                     /evalue="1.60E-29"
                     /label="B083_RS0118480_Thioesterase.1"
                     /locus_tag="B083_RS0118480"
                     /protein_end="2403"
                     /protein_start="2145"
                     /score="95.9"
                     /tool="antismash"
                     /translation="PLFCVHPGGGSAHWYQRLLPHLAPDLPVAALEWPGLQSGPGLPVP
                     TASEMAQRYVAEIRAARPHGPYRLLGWCGGSGITAEMADRLRADGEEVTFVLLDPGLDS
                     HERQGLWEEFRLIESCTAKLEELAAAGPEEDTGALREEILKLLDHLVDDADPETGIVLP
                     EHNGADVWLPSARIWREVMEMTLTYRHHHVPGTLHLVISDELARGEHEVALGQSYEEYL
                     SRWRELNSGVEVHRVPGDHFGVMRLPHVTSLASTLA"
     CDS_motif       33095..33166
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0118480_0023"
                     /evalue="1.60E-07"
                     /label="NRPS-te1"
                     /locus_tag="B083_RS0118480"
                     /protein_end="2231"
                     /protein_start="2207"
                     /score="23.8"
                     /tool="antismash"
                     /translation="PHGPYRLLGWCGGSGITAEMADRL"
     gene            complement(34098..>36371)
                     /locus_tag="B083_RS0118485"
     CDS             complement(34098..>36371)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580239.1"
                     /locus_tag="B083_RS0118485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_028418006.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-47, bitscore:
                     157.0, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RWRLWEQFSLRGPGFPVGGVLDLAPVDVSVYADKFAGGVLSGPDW
                     EEFEGVFGEVAARTAVRLQGVAGSSDFTAAVAWQNRTVLRTGLRPFLGWVPSASGRSSM
                     PRQREELVAHYWQRFCVKNDTIGFFGPVGWGRVDGSVGGVEVDPGEGLTASSSVFFSSW
                     SIDALARTLSADERLMAWIPPRRLPYIRAESHEGPVHVPGRRPQQAPPHLVALLRLADG
                     RRSPHELARILGTSLDEVTSRLTELVRRRWVSWRLEVPSGARPDRELRAVLERVGDAEL
                     RRGALEPLEVLERGRERVEAAGRDAEALCEALAALEEDFTRITDTASQRAKGSGTAPNR
                     SLVHSDTRRSATARIGGTVLDAMAPLDPLMTSAAWLMGRLGARVEQRAVEVYEKLSAAS
                     GEERVNLADFWFASMPILHGDAVTDAQEVLAEFQRRWARIIPLPEGEARVRATHSAVAS
                     QVAEAFPPVPVAWTAARYLSPDVLIAARDTEAIGRGDFELVLGELHLASNTMGASLFVS
                     QHPEPAELLRLTGRDHPGPRLLPLLPKEHKARLSTRVRNVLVRPEDYYVALMELTADPH
                     RDRTVLSADAHVVLRDGRPVVVLPGGAEFPVTDVFGHVLTTLAMDLFRLFPDADHVPRV
                     MVDKLVVSRESWRFTGGELGFAEEKSEARRYVRARNWRGERGLPRYVFVVSPTEPRPFY
                     VDFDAPVYVNILAKAARRLARKDPEAKLTITEMLPSPEHAWLTDDRGNAYTSELRFVAV
                     DQHD"
ORIGIN
        1 tcagcgacaa cgacttcgtc ctgatcgact tctgggcttc ctggtgcggc ccctgccgac
       61 agttcgcgcc ggtctacgac tcggcgtccg agcgccaccc ggacctcgtc ttcgcgaagg
      121 tcgacacgga ggcgcagcag gagctggccg ccgccttcga catccggtcg atcccgacgc
      181 tgatgatcgt ccgggacaac gtggccgtct tcgcgcagcc gggtgctctg ccggaggccg
      241 ccctggagga cgtcatcggc caggcccgga acctggacat ggacgaggtc cgcaagtccg
      301 tcgaggagca gaagcgggcg gcggaggccg ggcagcaggg gcagtccgag ccccagtagt
      361 cgcccgcccg cccttctgat cgccgtttcg ccgccgtacg ggcccggggt gccgggcccg
      421 cggcggattc ggcgcgtccg ggcgtcggcg gacgcgtccg ggctccggcg tgttcagccc
      481 gtcgggcgca ctccgtcggc cacctgcacc gacatgcccg ggtccagttc ctcgccgtcg
      541 accagcacgg cctccaccgt gcgggtctcc gggtcgatgt ccgcctccat gccctccccg
      601 gtgtaccggg ggtagcccga ggcccccgtc ttcccggtgg cggagacgac ggccgagcgg
      661 agcggacgtc cgggggctcc ggtccgcgtc cggctgtggt cggggatcag gaggagttcg
      721 taactctgcg ggtggctcat ggtcccgacg ctagacatcc gcagccggcc gcgcatgtcg
      781 tcgcgccggg gcggtcagct ggagtcgcgg tgcacggcgc cggtgcgcag caggtcctgg
      841 tggacggggg cggtgcccgg gtggtggacg agccggtcga tcgtctcggc cagcggctgg
      901 tccatggcca gctccatccg gaccgtgctc agccgcggcc gcagcagcct gccgagcagg
      961 aggtcgtccg ccccgatcac cgccgtgtcg ccgggtatcg cgacgcccgc gtcctggagc
     1021 gcgcgcatca gcagcatggc gtactcgtcg ttgtacgcga acaccgcgtc cagccccaaa
     1081 tccctccagc gccccgcgag ttccgccgcc gactcctcct cgtagccgag cggcaggggg
     1141 tgcacccggg ccccggccgg ttcggccgtc tgccgggctc cggcgaggcg gggttcggag
     1201 aagggcgtga ggcccggctc ccggggcatc accaccccga tgcggcggcg gccgcgcgcc
     1261 agcagatggg cgacggcgct ggcgccgacc cgccgctggt ccatgaccag cccgtgggcg
     1321 cccgccaccg gctccgggcc cagggtgatc accgctttgg cgccggaacg ggtgaggacg
     1381 tccgtgccgt gcggggtgag ggtgatgccc ggcggtacga cgacggcgac cggccgcagt
     1441 tccgcccagg cccgtaccgc ctcgtcgtcc gcgaggccgg cgctgccgta ctggacgacg
     1501 gtgtagtcca ggcggcgcag ccccgcctgg agttcctgga agaagtgctg gtggaggggg
     1561 ccggagggta tgtgcccgga gggcagcagg accaggcggc tgtgtccggc gcgcagactg
     1621 cgggcggcgg cgtgcgggac gtaaccgagc tgggtggcgg cctccctgac gcggtgccgg
     1681 gtgggttcgc tgatccggac ggcggcgttg ttgttcagga cgtacgacac ggtggcccgg
     1741 gacactccgg cgaggcgcgc cacatcggcg ctggtcggta cggagacttc ggtgggctgc
     1801 ttgggtaact ggctcatggc gagcggcagt cttccagatc cgccggaccg gccggtgccc
     1861 cgggggcacg ctcgtgcgac ggctcgcccg ggccccgccg gacgcccccg ctccccgtcc
     1921 ggggccccgc aggtcatacg gtgtggcgat gacgttccac cacagcgcag agcgcaccga
     1981 cagcccgtcc gtactccccg gcagcaccgg tccgaccgcc accgtccagg ccgatccccg
     2041 cgcggtgggc ccggtccgca cctcgtacgc ccccgaccgc gacggcgacc cggatccggg
     2101 cgagatcgtc tggacctggg tgccgttcga ggagaacgac gggcgcggca aggaccggcc
     2161 ggttctcgtc gtcgcgcggg aggcggcggg caccctgctc gccgtccagc tctccagcaa
     2221 gcagcacgac atggaccacg agtgggtggc gctgggcgcc ggtccctggg acagctccgg
     2281 acggccgtcc tgggtcgatc tggaccgggt gctgcgggtc cacgaggacg ggatgcggcg
     2341 tgaggcgtgc gcactggacc gcgaccggtt cgacaccgtc accgggcggc tgcgggagcg
     2401 gtacggctgg agctagtggc cgcgcggcgg ggtccggggc ggggtccggg gcggggtccg
     2461 gggcgggcgg gagctcacgg ctcccgcccg tatcggcccg gtcggcgcag cctcgccggc
     2521 cgggcccgta acggggccgg ggcccgtaac ggccggcgga ccgcaccggg accggcggcc
     2581 gggcgggcag ggccccggag ggctcgtccc gccccgccta ccgttccccg gccccgaagg
     2641 tccgggtgaa ggccgcccgg accggtgagt cgggggtgcg gtccaggatg ccgaacacga
     2701 cctgctcgaa gtgggcaccg aaccggccgt ccccgacgag cagcgccccg aacgccgccg
     2761 ccacctggac cgggtcgttc cggaagaccc cgcagcccca ggcgcccagc acgagcctgc
     2821 ggtagccctc ggcggcggcc acctccagga cccgttcggc gcgggcggcc agggcggcgg
     2881 ggacgcggtg ggcctcctcg gggacctgcc gccggatcac tccggcgttg ggcgccgggg
     2941 aggtcaggaa tccggcctcg tacggggtgt cgaggaagcc gccccggtcg tcgcggaaga
     3001 cggggacgcc gggcgagtgg atcacccggt cggtgtagaa ggggctgcgg tcggcgcggt
     3061 ggtgcgcgta gtacgcggga gcgcgcagca gggtggtgtg aagggccgag ccccggcaaa
     3121 gggcctcctc ctgggcctgg gcgccgttca ggtagccgcc gccggggttg cgggcggagg
     3181 cgtagctgag cacggcgacc tttccggggg cctcctcggc catccgccgg gccgcccgca
     3241 ggctgctctc gccggtgacc tcgaagcggg gcgtccggtc ggtggccggg gcggtcacgg
     3301 gcaccggcgc ggggccgtac agccgggtgc cggagcgggc ggccgccacg gcgcgctcga
     3361 tggacaccgc gtgacctgcg gcgttgcgat agtgcccggc ctcgacgacg gcttcggtct
     3421 cccgcgcgat accgcgcagc cgcgcgctca cctgcgctcc cccctctggt gcatacggtg
     3481 catgctggtc gtgggagcgg tgtggcggca acagcttttc cggtggctca ggggcactct
     3541 tgtgcgatcc ctgggtacgg gtttgggtgg taggtacgca actgagaagg aggcgcctca
     3601 tgtccccgga cacacccggc ggccccggac cgcggccgga atcctccccc ctcgacgagg
     3661 gcacggcaca ggatttactg cgcggcatct gtttcaagac gggccccccg cgcatcgtcg
     3721 gggtggaact cgaatggctc atccatgacc tggaacatcc gaccgtgccc gtggcccagg
     3781 agcggctgga cggcgcggtc gcggccctcc gcgaactgcc cctgagtgcc gcactgacgt
     3841 tcgagccggg cgggcagctg gagctcagct cccagccggc cggctccctg atggagtgcg
     3901 tcgagacgac cgcggcggat ctggccgccg tccggggttc gctcggccgg gccgggctcg
     3961 ccccggtcgg gtacggcgtg gatccgtggc agacgccgca ccgccggctc cgcgagcccc
     4021 gttacgacgc catggaggcc gctctcgacc gggcgggtcc ggccggtcgg gcgatgatgt
     4081 gcacctccgc ctccgtgcag gtctgtctgg acgcgggcga ggaggagccg gggccgcgcg
     4141 gctacggccg gcgctggcag ctcacccatc tcctcggtgc cgtcctggtg gcggcgttcg
     4201 ccaactcgcc cttccggcag gggcgccgga ccggctggaa gtccacccgg caggcgctgt
     4261 gggccgacct cgaccccgta cgcaccctgg cgccgggcgg cgggctcccg ccccgggagg
     4321 cgtgggccgc gcatgtgctg gacaccaccg tgatgtgcgt gcgccgggag gacggcccat
     4381 gggacgtgcc cgaggggctc accttccggg agtggatccg caccggagcg ccccgcccgc
     4441 cactgcgggc cgatctcgac taccacatca ccaccctctt tcctccggtc cggccgcgcg
     4501 gccatctcga actgcgcatg atcgacgcgc agagcggccc ggacgggtgg ctggtgccgc
     4561 tcgccgtcgc cacggccctg ttcgacgacc cggaggccgc cgagacggtg taccgggccg
     4621 tgaaacccct ggccgagtcg gccggttccg ccgccgcgcc gcgcaacgcg ctgtggacga
     4681 cggcggcccg cgaggggctg gccgatccgg agctgcgggc ggtggccgtc ctctgtttcg
     4741 agacggcgct cgacgcgctg gaccgcatgg gggtgagcac cgccgtacgg gacaccgtgg
     4801 cggacttcca cgaccggtat gtggcccggg gccgatgtcc ggccgacgat ctgctccgac
     4861 cgggcgccct cgccgagccg gtcctcctct ccggcgccac ccgcgcgccg accgcaccgt
     4921 cgtccccggg aagggtggcc tccgcatgac cgacgaccgc accccctccg ccgtcgccgc
     4981 ggacggcttc ccgacgggct ccggcggcca cgatcccgag gcgctccggc aacgggccct
     5041 cgatgccctg ctgaccgcca gggcgcgcac caccgtcctg accgacagtg tggacgaggg
     5101 cgaactcacc gcccagcact cccccttgat gtccccgctg gtctgggacc tggcgcacat
     5161 cggcaaccag gaggagcagt ggctgctccg cgcggtgggc gggcgcgagg cgctgcgccc
     5221 ggagatcgac gggctgtacg acgccttcga gcacccgcgc gccgcccggc cctcgctgcc
     5281 cctgctggcg cccgccgagg cccggacgta cgcctcggac gtacgcgggc gggccctgga
     5341 catcctggag gccgccccgc tgcacgaggg cggacggccg ctggagcggg ccgggttcgc
     5401 cttcggcatg atcgcccagc acgaacagca gcacgacgag accatgctga tcacccatca
     5461 gctcaggtcg gggccggtcg cgttgaccgc gcccgccccg cccgatccca ccgataccgt
     5521 ctccctgcct gccgaagtgc tcgtccccgg aggtccgttc accatgggca cctccgccga
     5581 gccgtgggcg ctcgacaacg aacggcccgc gcaccggcgg gaggtggcgg ccttccacct
     5641 ggacacggcc cccgtcacct gcggggcgta ccggcggttc atggcggacg gcgggtacac
     5701 cgacccccgc tggtgggcgc ccgagggctg ggacatggtc cgcgaacacg ccctggacgc
     5761 accgctgttc tggcaccggg acggcgggca gtggctgcgc cgcaggttcg gggtgaccga
     5821 gtcggtgccg gacgacgagc cggtgctgca cgtcagctgg tacgaggccg acgcgtacgc
     5881 ccgctgggcg gggcggcggc tgcccacgga ggccgagtgg gagaaggccg cccggcacga
     5941 ccccgccacc ggtcgttcgc tccgctatcc ctggggcgac acggacccga cgcccgggca
     6001 ggccaacctg ggccagcgcc atctgcgtcc ggcgcgggcc ggcgcctatc cggcgggccg
     6061 ggctccgtcc ggcgcgggcc agctgatcgg tgatgtgtgg gagtggacgt cgagcgactt
     6121 cctgccctac ccggggttcg tggccttccc ctaccgggag tactccgagg tgttcttcgg
     6181 gccgggccac aaggtgctgc gcggcggctc gttcgccgtg gaccaggtcg cgtgccgggg
     6241 cacgttccgc aactgggacc tgcccgtgcg gcggcagatc ttctccgggt tccgcaccgc
     6301 gagggacgcc tgatgtgccg tcacatcgcc tacgtgggcg atccggtggc cctcgggtcc
     6361 gtactctccg cgccaccgca ctccctggtg cgccagtcct gggcaccacg ccgccagcgg
     6421 cacgggacgg tcaacgcgga cggtttcggc gtcggctggt acgcggacgg cgacccggtc
     6481 cccggccgct accgccgcca ggggccggtc tggcacgacg agaccttcac cgacctggcc
     6541 cgggtggtgc ggaccaccgc gatgctcgcc gccgtacggg acgccaccga gccgggtgcg
     6601 gacggggagg ccgcggccgc gccgtacacc tccgggcggc tgctgttcag ccacaacggg
     6661 gcggtgccgg gctggcccgg ctcgctcgcg gggccggccg ccgcgctccc cgcgcgggag
     6721 ttgctgtcgc tggccgcccg gaacgactcc gcgctggtct gggcgctggt cctgcaccgc
     6781 gtcgccgccg gggacgatct gccgggcgcg gtcgcggaga ccgtccgcga ggtcgccgag
     6841 gcggcgccgg gcgcccggct gaacctgctg gtcacggacg gcaccagcat cgtcgccacc
     6901 gcctggggcg acacgctctg gcacctccac gacccgggcc gctcgacggc cgtggcctcg
     6961 gagccgtacg acgacgatcc ccgctggcgc gaggtccccg accgtaccct gctggtcgcg
     7021 accgccgcag acgtcacccc cacaccgctc aaggagcccg cagcgtgagc ccattcctgc
     7081 tgacccgcac cctgccggag gacgccacgg acgcggcgct gcgcgccgac gtcctcagcg
     7141 ggctgacccg tcatcccaag acgctgccgc ccaagtggtt ctacgacgcg cgcggcagcg
     7201 aactcttcga ggagatcacc cggctgcccg agtactaccc gacccgcgcc gagcgggaga
     7261 tcctggagga ccgctccgag gagatcgccg ccgtctcggg ggcccggacg gtgatcgagc
     7321 tggggtcggg ctcctcggag aagacccgcc atctgctgcg ggccctgacc gggctggaga
     7381 gttacgttcc ggtcgacgtg agcgagagcg cgctgaccgg ggcggccgag tcgctgctcg
     7441 tcgaccaccc cgggctctcg gtccacgccc tgatcgcgga cttcaccggc ggcctcgccc
     7501 tgcccggcac tccggggccc cggctcgtcg ccttcctcgg cggcacgatc ggcaatctgc
     7561 tccccgagga gcgggcggga ttcctgcact cggtgcgctc gctgctctcc cccggcgaca
     7621 cgcttctcct cggcacggac ctggtgaagg acgaggagac gctggtcgcc gcgtacgacg
     7681 acgcggcggg cgtgacggcg gccttcaaca agaacgtgct gagcgtggtc aaccgggagc
     7741 tgggcgccga cttcccgctc gacgcgttcg accatgtcgc cgtgtggaac ccggagcagc
     7801 gctggatcga gatgcggctg cgggcccgcc gggcgctgaa ggtgaagatc cgggagctgg
     7861 atctggtggt gccgttcgag gccggtgagg aggtgcgtac ggaggtgtcg gccaagttcc
     7921 gcccggagga cgtgcgcgag gagctggccg cggccgggct ccggctcgct cagtggtgga
     7981 cggacgggga ggggcggttc gccctgtcgc tggccacagc ggtctgagga ggcgacggcc
     8041 gggcgggggc ggcggccggc ggctgtacgg gaagggggac ggggacagcg gtgggggccg
     8101 gggccacggc cggggccttc gccgctcccc gggccgttgg cgccgtgaat gctcccggcg
     8161 cgtcccgggc cgttggcgcc ctgcgtgccc ccggcgctct acgcgccgtc gtcgccggac
     8221 gcgccgtcac cgtgcggtcg ctgccgagga cggcggcgcg ggcggcgcgg gccagttcgc
     8281 ggcggccggg ctccccgtgc tcggagaccg gggcgtaggc gcgtgccggg atggcggcga
     8341 ggacgtggac ctcggcggtc agtccggccg cccgcaccac ccgccagagg gaggcggtga
     8401 gcgggtcgtc cccgacgaac gcggccgcgc ccgctccccc ggtgccgtac gtgatgcgca
     8461 ccggccgtac ggaaacctcg gcgtcgatgg ccgcctggaa cacggcgggc cggaacgccc
     8521 cgccccgccc ccggccgcac caggtgctgc cctcggggaa gaccacgacc cgggagccgg
     8581 agcgcagggc ggtggcgacc gaggcaaccg cggcgggcag cgcgcgcagc cggtcccggt
     8641 cgatgaagag cgtggagccg aacccggcga gccggccgag cagcggccag tcgcggacct
     8701 cggtcttggc gagcatccgg ccgggcagca cggcggcgac gagcgggacg tccagccagg
     8761 agaggtggtt ggcgacgacc agttcgccgc cgtcgcctcg gacgtccgga tgcccgcgga
     8821 ccgtcacccg tacgccgaag gcccgcggta tgccccgcgc ccagtaccgc agcagccgcg
     8881 tccgcggcgc cctggggagc ggccggaccg gcgcggcgca gaccactccc agcagcaccc
     8941 acccgcagcc ggcgagaagc cgcagagcgg cgcggagcgg gggccgggcc gctccggtgt
     9001 gccgggcgca ggagaccggg gcgcaggggg cgacgggcag ccaggcgctg gtgcccgccg
     9061 gacggggggc gggcctgtcc tcggtgcggg aggtgctcat gcctgcggta cgagggagag
     9121 gaagtggcgg aggtagcgcg ggtcggtccg gcgcagcgag agcaggacgt agaggtcggc
     9181 cacgttgaac tcggggtcgt acgccggtgc tccgcagacc caggcgccga gccgcaggta
     9241 gccgcggagc agcgggggca ggtccgcccg ggagccgttg cccgcgtcgg ggtgcgcggc
     9301 ggcgtcccag aggcggtgcg gggtgaccca gtgctcctcg ggggcgaggt gcgcggtgcg
     9361 tacggtgttc cagctgcggg cggcgagggt gccgccgtcg gccagcggga gggagcagca
     9421 gcccgcgagc caggtgtggc cggagcgctg catgtagcgg gcgaggccgg cccagacgag
     9481 ggcgatgacg gcgccgtcgc ggtgggcggg gtggacgcag gagcggccga cctcgacgag
     9541 gtcgtcgcgg atgggggcga ggcggccgag gtcgaactcg ctctccgcgt agagccgtcc
     9601 ggccatccgg gcgcggtcgg gcgggaggag gcggtaggtg gcgacgacct ggtccgtggc
     9661 ggtctcgcgg accaggaggt ggtcgcagta cgcgtcgaac gcgtcgacgt ccaggccggg
     9721 ttcgggccct tcgaggcggg cgcccagctc gccggcgaag acctggtggc gcaggcgctg
     9781 ggcggcgcgc acgtcctccg ggccggtagc gagggagacc cggtaggcgg cggccggttc
     9841 cggggagcgg ggagcggcgg cggccggtgc cggggggacg ggccgggtgg gcggcgcggc
     9901 gggcggggcg gtgggcagca cggtcatggc ggtctccggg gacggatcgg cgaagtcggc
     9961 tgccgggccg tcgcgcgcgg cgaaggcccg gccccttact tcttccgtca ccggctggat
    10021 tcgacgtgac cgctgtggag cgcggggatg tgcgacggct gaatcccgag ggacgcggcc
    10081 ggggcggacc gggccgggag cggttgcgga cctgcccggc ccgcaccgac gacacccgac
    10141 ggcaccggcg ggcacccgtt cggtaccgac tcgcacctgc ggcaccgaac ggtgtgtgcg
    10201 cccgcccgga gcgacgcccg accgggcggg cccggcgctc cctcagctgc cggcgagcat
    10261 cgccgtgatg cgctccgacg ccttcttcgc ctcctgctcc gggtcgccgc ccgtgagcac
    10321 cgccgtcatg tacggcttga tcgggttctc cgcctcgacc ttggcccact gggaggagtt
    10381 cggggtggcg cggccctggc tcgccccttc ggccatcgcg gcggtgccct cctcgccctc
    10441 gacgacatgc gccaggctgg gcttgttggg cacgtagctc atggtgcggg ccagctccgt
    10501 ctgccacttc tcgctcgcca gcgccttgac gacggcgata ccggcgctgc gctggtcggc
    10561 cttcttcggc acgatgaggt ccgagccgcc ggtgaagacg gagcccgggg acttggcgga
    10621 cttgccggga atggggaagt agccgagctt tcccttgagt tcggggttct gctgctcgat
    10681 gagcgcggcg ctgccgggga gcgagatgat ctgggcgacg ttccccttgg cgaatacgtc
    10741 gttctgcggg ggcttctcct cgtcggagtc catgggcccg tcgccgagcg cctggagttc
    10801 cttgtagaag ttcattccgg cgagcgcttc cggggtgtcc agcgcgcccc gccagtcacc
    10861 gccgccgccc tccgcgagtt cgccgccctc gtcccagatg aatccggcca gtacgtacca
    10921 gttctggccg gccagataaa tgccctggtt gccctgcgtg ttgagctttc cggtgtcctc
    10981 gatccactcg gcgcgggtct tgggggcgtc gtcgatgccc gcggccttga agatgtcctt
    11041 gttgtagatc accacgcggt tggccgcgta ccaggggatg ccgtactgga ccccgctgat
    11101 ctggccgggc tgggcgaggc cgggcagcca gtcctcgctg cccaggtcgc gcatcgactc
    11161 cagggtgagg tctcgcaggt tgccgctctc cgcgtactgc gccacctgtg tgttgccgac
    11221 ctcgatcacg tccggggcgt cgtcgctctc cagggcggcc aggaccttgg ggccgatgcc
    11281 gctccactcc tggatcttga aatccagctt gacggagggg ttctccttct cgtacgtgct
    11341 ggtgaacttc tccaggaatc cctgcgagac gctgtccttc atcagccaga ccgtgaccgt
    11401 acggtctccg ccacccgaac cggagaagta cccacatccg ctgagcgtga cggacgagac
    11461 gagcgcgacg gctccgacga gtatgcggtt cttcacgtag tcaccttctg cgaaacggca
    11521 cgacgaaatc aggacccggt gtggggggat tgcgggcggc gctcgcacgg gtgggtggct
    11581 gaattttggt atggaccatt cagtaggtca aggcgcgtgc tcgtcccggt tcgtccctgg
    11641 tcgccccctc gcgcgagacc cgggattgag gcacggtggt cagcagagag gagacagaac
    11701 atgcccaacc acacttatcg ggtcaccgag atcgtaggaa cctccgagga gggcgtcgac
    11761 gcggcgatcc ggaacggcat cgcaagagcc gcggaaacgt tgcacaatct cgactggttc
    11821 gagattaacc aagttcgggg ccatatcgag gatggccgaa tcgcgcacta ccaggtcggc
    11881 ctgaaggtgg gcttccgtct cgacgaaaac ccctgatcac ccctcggttc ccctctggtc
    11941 aggtccgtcc gtcccgctcc tgggcgtcct tcagcgcctg cgaggggtcg gaccagcggg
    12001 cccgcaccac agggaatcca gccacttcgg ccgcggcgca gaccagctcg tcgtcgtcga
    12061 ccagcatgcg tacctcacgc gaccggccca gccgccgcag gatgtccagc ttcgtccggc
    12121 gggccgggcg ccggtcgtcg ttgcgccgca tgaacaactg cccgccgggc agcccctgcc
    12181 ggtccagcca ctccacggtg tcccggcggc agcgctcggg ccgcccggtc agatagacga
    12241 tctcgcactc cgcggcgctc gcccgcacga gcgccacccc gtcggccagc ggcggatcgg
    12301 ccggggcggc ggcgaagaag ccggcccagt cgcgcttcgg gccctccagg aagtgctgtc
    12361 ggtgggccgt gtcggcgagc gtgccgtcga ggtcgaacac ggccagcggc cgggcgtcgt
    12421 cgttcatcgg gccagcttag gaaggctcgg cgccgaccgc gtgccgaacc gctccggccc
    12481 tgtccccggc agccggcacc caccgcgcgg cagcgggggc aggaggcgcg cgcagcccac
    12541 ggaccgcggg cgcgtgcctc ccctcccccg cccttccggt gcgcggtgcg ccccgggccg
    12601 gacgggaagg accggcgggc gtccgccgcc gtcaccgctg cccgtttgtc tctacggtcg
    12661 gccgatgcca gaaggcactc tcactctggc gccggtatcg accgcggcgc gaccaccgac
    12721 cgaggagaga cggcgatgtc cgaccacacc gagagcgtct accgcgtcgt actcaacgac
    12781 gaggagcagt attcgatctg gcaggccgag cgcgagctgc ccgcgggctg gcgggccgag
    12841 ggaacccagg gcagcaagga ggagtgcctg gaccacatcg gacgggtgtg gacggacatg
    12901 cgccccgcca gtctgcgccg ccggatggag ggcgaggccg ccggggcggc cgccggtagg
    12961 gccggacgcc agagcctccc ggtctgatcc gcccaccgac accgagggga agtccggcga
    13021 tgaactccgt ctcccagccg agataccggt cggccctcgt ggcgcaggct gccgggcctg
    13081 cggacgagga agccctaccg cacgacacca ctcagccgtc cggccccgcg tccgccgggt
    13141 acggcccggg ccgtgcgggc gccctgtcgg ccgtcggcgg gacaccgctg gtggaactga
    13201 cccggctggt gcccggcgcc cgcttccggg tctgggccaa gctggagtcg gtcagcaccg
    13261 gcggcagcat caaggaccgt tccgcctatg ccatgctgag ccacgccgtc gccaccggcg
    13321 cggtggtccc cggcagcggc accgtggtcg agtcgagctc ggggaacctc ggcgtcggca
    13381 tggcccaggc ctgccgcgcc atggacctgc ggttcatctg cgtggtggac ccgcgcacca
    13441 atccgcagaa catcgcgatc atgcgggcgc tgggcgcgga tgtgcacacg gtcaccgaag
    13501 gcgacccggt caccggcgag ttccagccgg tgcggatcgc ccgcgtgcgc gagctggtcg
    13561 acgcgctgcc cggcgcctac tggcccaacc agtacgccaa cccccgtaac tcctgggcgc
    13621 accggatcac catggcggag atcgtcgagg acctgggcac cgcgcccgac tacctgttct
    13681 gcaccatcag ttcctcgggc actctgcgcg gctgcggcga cctcatccgc gaccgcgggc
    13741 tccccacccg ggtggtcacc gtggacgccg agggcagtgc catcttccgg ccgccgaccg
    13801 ggcgccggct gatccccggc cacggcgcgg cggtccggcc cccgctctac cgcagcgggc
    13861 tcgccgacga ggtggtgcac gtcagcgacc tggacagcct ggtgggatgc cgccgactgg
    13921 cgctgcgcga agggctgttg ctcggcggct cctccggcgc ggtggccacg gccctggaac
    13981 ggacgggcga ccgcatcccg gacggtgcca cctgcgtact gatgatgccg gaccgtggcg
    14041 aacgttatct gaacacgatc tacgacgacg ggtgggtgga gcgccagttc ggcgaggtgt
    14101 cccacctgtg gaaggacgag gtggccgacg tggccgagaa cagcgggatg accggggtgg
    14161 caggatgctg acgatcggca acggagacgt ccggcggctt ctggacggcc gggagcggga
    14221 ggtgctgaac gccgtgcgcg aggcgtatct gctccacgcc gccgaggaca cgtcgctgcc
    14281 gcactcggtg ttcctgcgct ttcccgacga ccccggcaac cggatcatcg gactgcccgc
    14341 gtatctgggc ggggcggagc cgctggccgg aatgaagtgg atcgcctcct tccccggcaa
    14401 cgtcgcggag ggtctggagc gcgcctccgc cgcgatcatc gtcaactcca tgcggacggg
    14461 caggccggtg gctctcgtgg agggctccac catctccgcc cgccgcaccg cggcgagcgc
    14521 cgccctcgcc gcggccgctc tgccctccgg ggacggccgg gagacgggcg tgtcgctgat
    14581 cggctgcggt gtgatcaact tcgaggtgct ccgcttcctc ctggtggtac ggccggagat
    14641 caccgacatc accgtccacg atctcgatcc gcggcgggct gcggacttcc gggaccgctg
    14701 ctccgccgaa ctggccgggg acggacgggt ggtgcgggtg gcggagagcg ccggggcggc
    14761 gctctcggcg caccggctgg tcagtctggc gaccacggcc accgtgcccc acctggatct
    14821 cgacgcgtgc ctgccgggca cgctggtgct ccacgtctcc ctgcgggacg tcacggtcga
    14881 gggcgtgctg gacgcggtga acgtggtgga cgaccccgac catgtctgcc gggcggccac
    14941 atcggtccat ctggcggaga cccgggtggg cagccgctcg ttcatcgaca ccacgctcgg
    15001 cgagctgctg agggatgcgg aaccgggtcc gcgggacccg gcacgcacca ccctgttctc
    15061 gccgttcggc ctcggggtac tggacctggc cctggccgga ctggtactgc gcgaggcccg
    15121 cgcggccggt gtcggccagg agatctccgg cttcctcccc gaatcccggg tcgccgagac
    15181 cgtctgagtc ggccgcgcct ggggaacggc cccccatatt tcggccgtgc ccccaccccc
    15241 cttggccaag aaccgacttc tcgcaggtca gagccggtcc ccacccacag cccccgtgcg
    15301 ttcccggacg cgcacggggg ctgttttccg ttcatgggca ccgtgtgggc acgcggaggt
    15361 gggggcgtcg cggaaatctg ggggtggtgc accgatgtcc cgcgcgccct cgatcttgat
    15421 gctcggtgtt accggcgaga gccgttaccg agcgaggagg aggatcccat gaggaatacg
    15481 gtgcgggtga gcgtcgtcgc tgaggacccg gtgctggagg cgggcaccct gagcgccctg
    15541 gcgagcagcc cggaggtcct gcccgccgtc ggggacgaac tccccgacgt gacggtcgtc
    15601 gtggtcgacc gggtggccga ccccgttctg gacctgctgc gccgcacccg ggccgccgac
    15661 caccgtccgg aggtcgtcct cgtcgccacc gagctgggcc cgccggaggc actgcacgcc
    15721 attgccacgg gtgcccgggg tctgctgcgc cgccgggaga ccagcggccc gcgactggcc
    15781 cacgccgtgc tggccgcggc gagcggggac tgcacggtgc cgcccgatct gctggacggg
    15841 ctgctggagc agcgtacgga ggacgcgggg gcgggtgtcg ccgacgcctg gggggcggcg
    15901 gggctcagtg agagggaacg cgcggtgctc cggctggtgg ccgaaggcca cgagaccagc
    15961 gagatagccg gacggctctc ctactcggtc cggacggtga cgacggtcat gcacaacgtg
    16021 acccagcgct tccggttgag aaaccgcgcc cacgcggtcg cctacgcgct gcgggcgggt
    16081 ctcctgtgag ccccgcccgg gcgctggccg gcgccgccgc gccccaccgt gccgccaccg
    16141 accggaccgc ggtacgcgtc catgtgcgcg ccgcggacga cgacctccgc agctcctggc
    16201 accggcggct gaccggggcg ggaatcccgc tggtggaggg cggacggccc gaccccgatc
    16261 tggtcgtgct ggccgccggg aggaccgtgg acgaggcggt cgcgtcgtgc cctgcccccg
    16321 aggccggggg gaccaaccgg cacggggtcc tggtggccgc ccagtcggtc tccccggacg
    16381 gtgtgctgcg ggcggtgcgg gcgggggccc ggacgatcct gcggaccacc gacgccactc
    16441 cggagcagct ggtggccgcc gtgcactcgg cccaccacgg cgacggccgg ctcccctacg
    16501 gcgtgctggt gcgtctgctc ggcgcctccc agcagtcggg gcccgagccc gcggcggctc
    16561 tccccgacgc tccccggacc gcccggacgg ctccgctgac tccgcgccag acggcggtgc
    16621 tcaccctggt cgccgagggg cacggcaacg cggtgatcgc ccaggcgctg tcctgctcgg
    16681 agcacaccgt caagaacgtc atctacgagc tgatggcccg gctccaggtc aggaaccggg
    16741 cccatgcggt ggcgcgcgcg gtgcgagcgg ggctgatctg acggaccggc cgcgccggag
    16801 ccgcgaaccg cgtgcgggcc cgaggtcggt gacctcgggc ccgcacgcgg ttccgccgcg
    16861 tcagtggacg agatcaccgc ggacggtgcc gctgccgggc gcgggctcgg ccagatccga
    16921 accggtcggc gcgacctgcc ggttgtgctg gtccacgtgg acgacgctgg gcacgagcgc
    16981 cttggcctcg gcgtcgggga cggaggcgta cgagatgatg atgaccaggt cgcccggctg
    17041 gaccagccgc gccgcggctc cgttgatgcc gatgatcccg gtgccgcgct ccccggtgat
    17101 gacataggtc tccaggcggg cgccgttggt gatgtcgacg atctggacct gctcgccggg
    17161 gagcaggtcg gcggcgtcca tcagatcctc gtcgatcgtc agcgatccga cgtagtgcag
    17221 atcggcctgg gtgacggtgg ctcggtggat cttggacttg aacatggtcc ggaacatggt
    17281 gtggtctcca gcgtctgtcg tacgggaagg ggagggacag cgggtcgttc agtggggcgc
    17341 gtcggggctc gccccggcag gtgtcctgcg gggttcggcg ggagcggggg cctccgcggg
    17401 caccggttcc gcgggggcgc tgatcgcggt catcgtggcc aggcgcaccg ggcgggagaa
    17461 ggtggcggcc agggccatga gcaccatcca cccggcgagc accgccgcgg cggcccgcac
    17521 cccgaaaccg tccagcagca gcccccctgc cagcgccccc agcgacagcg cgccgttggc
    17581 cagcaggctg gacgcgctca gcacccggcc ccgcagtccg tcgggggtga cggccagctg
    17641 gtaggtgccg accgccacgt tccagatggg tccgacgaac cacatcgccg tgtaggcgat
    17701 cgcggccggc cacagcccgc cgccgaaggc gagtacgcac atgagcagcg cccaggccca
    17761 gttggcgccg atcacgaggg agttcatccg gagcgtgcgg ccgatccggc cggcgaccag
    17821 cgccccgagc attccgcacc ccccggccac gcccacgagc acgccgatgg cggccggacc
    17881 cgcgccctcc tccgccagca gcacgatcat cagcaggaag agcgcgcgga acaggaggtt
    17941 gctcccggcc accaggagcg cggtggtccg cagcagcggt tgccgccaga gccaggtgag
    18001 gccctcggcc atccggcccg cctgccgccg cacccgggtg cggcggctct cccccgccgc
    18061 gccgccggcc ggaccggccc cggcgcgttc gccggggcgg gccgtctgga agtccttcct
    18121 gatgcccagc agggtggcga gcgagaccag atacgcgaag gtctccagca cgaaggggac
    18181 cgcccggccg acgccgaaga ggatgccgcc cagcggggtc ccgatcatgg tggcggcccg
    18241 gccccgcgcc tcgttccccg cgagcgccgc cgacagctgg ctggggtgga ccacgttggg
    18301 cacggcggcg gtggaggcca gcccgttgag cacggtgagc gtgccctcca cgaacccgac
    18361 caccatcaca tgggccagcc ggagttcgcc caggagcagg gccagcacca cgctcgccgc
    18421 gccggccgca cgcagtccgt cgcaccacat catcacgcgc ttgcggttcc agctgtcgac
    18481 caggatcccg gccggcagct ggaagacgag ggcgggcagc agcaccacga acccgaccag
    18541 ccccgcggcg gagggcgacc ccgtgaccgc gagcaccagg agcgggtagg ccaccgtgga
    18601 cgccgtggat ccgatgatcg ccaccgccga accgctccac aggagcagga aatcccgatt
    18661 gcgccgcaac ggcggtggcg cgggtgcggc acccgcgtgc tcggcgaccc tgctcatgga
    18721 tctgtcctcc actcagacac gggaaatcct ctcgaaggcc gcacggaaga cccggcacca
    18781 cggtcggggc gaccgggccg cacggtgacg tcagcgtgcc gcgcggcggc ggaccggccc
    18841 agggaaggac gcgcagaatg gcacgcaccc accgtgccga cgactccgcc ggatgttctc
    18901 tgccctgccg gaggccgtac gccgaccctg gccggtatga ccgcaaaccc ttcagccctg
    18961 ttcacgccgg ccgccgccgg gtcccggacc tcagggcaga cgcttcctca tctgatgacg
    19021 gccgcccccg ggggctccgc ggcggaacgg ctggccgacg cccggccgga gatccgcgcc
    19081 cggctgcgtg agcacggtgc cgtgctgctg cgcggattcg gcgacgacgg cgtggacggc
    19141 ttcgaacgga cggtccgtgc catcggcggc gagccgctga cgtacgcgga gcgctcctcg
    19201 ccccgctcga ccatcaaggg ccaggtctac acctcgaccg actatccgcc ctccgaggag
    19261 atcttcctcc acaacgagaa ctcctaccag gcgacctggc cgctgacgct gttcttcctc
    19321 tgtgtgaccc cgcccgacac gctgggctcc accccgctcg ccgacacccg gcgggtgctg
    19381 gccgcgatcg atccgcaggt ccgggaggag ttcgccgccc ggggctggat ggtggtccgc
    19441 aacttcaccg acgggttcgg tgtcccctgg cagcacgcct tcaacaccga ggaccgggcc
    19501 gaggtcgagg cgtactgcgc ccgcaacggg gtcaccgccg agtggacccc gggcggtctg
    19561 cggacccggg cgcgccgcga ggcggtgcac cggcacccgg tgaccgggga gcgcgtgtgg
    19621 ttcaaccacc tgacgttctt ccacgtcacc accctggggc cggacctctg cggtgcgctg
    19681 cgggagatgt acgacgaggc ggacctgccg accaacacct actacggcga cggcgccccg
    19741 gtgccggacg aggtggtggc acacctgcgg gactgctacc gcgccgagca gcggcgcttc
    19801 gactggcagc agggcgatgt gctggtcgtg gacaacatgc tggccgcgca cgcccgggag
    19861 ccgttcaccg gaccccgcaa gatcgccgtc gccatggccg agccctccag cggtccggtc
    19921 gaacagggct gacccgccgc ccggaccccg tacgccgacc gcttcaccgc cccaccacca
    19981 tctgcccagg gagacgaccg atggcacccg tcgacggcgg ttatccgctg tccttcgcac
    20041 aggaacagct ctggctgctc gaccagctca ggtcgggcga cgccgccgag tacctgatgc
    20101 acgaaacctt ccgtatccgc ggcccgctgg acaccgaggc gctgaacgcc gcgctcaccg
    20161 agacggccgc ccggcacgag gtgctccgca cccggtacgc cgaggaggac ggcgtcggcg
    20221 tccaggtcat cgacgaaccg gagccggtga aaccggagtc ggtcgacctg ggcgacgtcc
    20281 cggacgagca gcgcgagcag ggccttcggg agttccgcgc gagctgggcc gccacgcccc
    20341 tcgacatccg ccgggagcat ccctggcggg tggccgtggt ccggctggcg ccggaggact
    20401 gggccctgct gctcaccttc caccacatcg ccttcgacgg ctggtcctgg ggtctgctcg
    20461 ccgacgaact gcgcgcgtcg tacgcggcgt tcgcctcggg tggcaccccg gcggccgagg
    20521 agctggaact ccagtacgcg gactacgcgg agtggcagcg cgaatggtgg acggcccaac
    20581 ccgaactgat ggatcgtcaa ctgggctact ggcgcgaccg cctgacgggc acggccgcac
    20641 tggacctgcc caccgaccgg ccccgtccgg cccggtggga cgccacgggc ggcaccgtcg
    20701 ccttcaccgt gccggcgccc ctcgcggccg gcttctcggc actcgccaag gagcagggca
    20761 ccacactctt catggccggg ctcgccgcgt accaactgct gctcgggcgg tactccggcg
    20821 ccgaggacat cgcggtcggc gtctccctgg ccaaccggga cgacgcccgg ctggaacggc
    20881 tgatcggcct cttcctcaac acggtcgtgg tgcgcacgga cctgggcggc gccccggact
    20941 tccgggagct gctgtcccgg gtgaagagca ccacgctgga cgcctacagc caccaggagg
    21001 tgcccttcga gcgggtggtc gcggccctcg ccccggagcg ggacccgggg cgcaacccgg
    21061 tcttccaggc cgggttcgcg ctgcacaacg cccaccgccg cccgttcgcg ctcaccggcc
    21121 tggaggtcac ccgggtcacc ggcggcgcgc acagctccgc cttcgacctc tccctccatc
    21181 tgacggagcg tccggacggc acgatcggcg gcgagttcat ctatccgacc gcgctcttcg
    21241 accgggaccg gatggagcgc atggccgaga acttcctcca tctgctcggc caggcggtcg
    21301 cctcgcccgg caccccggtg gaccggctgg agctgaccgc accggcggag cgggccgccc
    21361 tcaccgcctg gggacagggt gcgacccggc ccgccgcgga ggaccgctcc ggccgcggcc
    21421 tggtcgcgat ggtgctcgac cgggcggccg ccaccccgta cgcgacggcc gtcgcgtacg
    21481 acggaggctc ggtggactac gccgggctgg ccggccgggt caccctgctg gcggcccggc
    21541 tgcgggagga gggggtccgc cccggcaccc ccgtcgcggt cgcactgcac cgcggcccgg
    21601 agctggtgac ggcgatcctg gccgtgctgg ccgtcggcgg tgtccatgtg ccgctggccc
    21661 ccgatctccc cgacgtccgc cgggagttcc tcctgtcgga ctccggcgcc gccctggtgc
    21721 tcaccgagga ggcgctgcgc gatcgcttcg gcgcggacgt cccggtgcgc gcactggacg
    21781 ccgagtgggc cgggaccggt ccggccgcct caccggcggc cttcccccac ccggccggcc
    21841 cggacgaggc ggcctgtgtc gtgtacacct ccgggtccac cggcaccccc aagggcgtgg
    21901 tggtgaccca cggcgggctg cgcaaccggg tgctgtggtc ggtggaggcg tacgcgatga
    21961 ccgcggcgga ccggctgctc cagaagacca ccatcgggtt cgacgcctcc ctctgggagt
    22021 tcctctcccc gctggtctcc ggcggcaccg tggtgatggc cccggcggac gcgcaccggg
    22081 acccgtccgt gatggccgcc gccatggacc gccaccgggt caccctgctc cagctggtgc
    22141 cctcggtgct ccggctgctg gtgcaggagc ccgccctctc ccgctgcacc gccctgcggc
    22201 tggtcagctc ggcgggggaa ccgctgcccg cccggctgtg cgagcggctg cgcgaggcgg
    22261 tgcccggggt ggaggtctcc aacacctacg gccccaccga gtgctccatc gactcgaccg
    22321 cccaccgcta cacgggcgag gggctgcccg gatccggcac ggtcgccatc ggcgctccgc
    22381 tgaccggtgt gggtgtctcc gtggtcgacc gggccgacct gctggtcccg gtcggggtcc
    22441 ccggcgagct gtgcgtacgg ggagccgggc tggcccgcgg atatctcggc cgccccgggc
    22501 agacggccga gcggttcggc gtcgacccgt acgccaccgt gcccggcggg cgctggtacc
    22561 gaacgggcga cctggtccgc tggcgtgccg acgggaccct ggagttcctg ggccggagcg
    22621 acgaccaggt gaagatccac ggggtgcggg tcgagccggc cgagatcgag gccctgctgc
    22681 tggcccatcc ctcggcgacc gcctcggcgg tcgtggcccg gcccggggcg cacggccagc
    22741 tggagctgac cgcctacgcc gtgcccgctg ccgggtcgga cccggccggg ctgcgggcgg
    22801 agctgctggc ccacctcgcc gcgcgtctgc ccgccgccgt cgtgccctcc cggctggtcc
    22861 tgctcgacgc cctcccgctg accgccagcg ggaaggtgga ccggggggcg ctgccggggc
    22921 ccgaggacgg catggcaccg cccgctgccg acgggccgga gcgcgccgct ccccgtacgg
    22981 cgacggaaca ggccgtcgtg gcggccatgg cctcggtcct ggagatcccc gaaccgggcc
    23041 cagatgacga cttcttcggg ctgggcggcc actcgctgct cgccatccgg ctggttctcg
    23101 ggctgcgccg cgccttcggc atcgagatga cggtcgccga cctcttcgcc gaccgcaccg
    23161 ccgccgccct ggccgcccgc atcgaccggg ccgccgggac ctccgaggag gaggaacccg
    23221 gtcaggcacc gggcgggatc gtgccggtgg cgcgggacgg cgtgctgccg ctctccttcg
    23281 gccagcagcg catgtggttc ctggaccggc tggagccggg gagccgggag tacctgatcc
    23341 cgctcgccct gcgcctgcgc ggaccgctgg acaccggggc cttccggcgg gcgctggagg
    23401 aggtggcccg ggtgcacgag gtgctgcgga cccggtacgc ggaccacgac ggcagcccgg
    23461 tccagctcat cgacccaccg ggcccggtcg cctaccggga ggtggacctc tccggtaccg
    23521 aggacgggcc cgtccgtgcc cgggagctgc tggaggaggt gctgaccgtc cccttcgacc
    23581 tggcggccga acaccccttg cgggtcacgg tgatccgcgc cgctgccgag gaccactggg
    23641 tggccctggc cgcccaccac atcgccttcg acgcctggtc gaccaaggtg ttcctgcgcg
    23701 acctggacac cgcgtacacc gcgctcgccg cgggccggga gacaccgctc cgtccggggc
    23761 cggtccagta cgcggacttc gccgcatggc agcgcgccca ggaggagacc ccggagaccg
    23821 gtcgtcagct gcggtactgg gtggagcgtc tcgggggtct caccccggtc gagctgccgt
    23881 ccgaccggcc ccgcggctcc ggccgcgacg cggccgggga caccgtgatc gtggatgtcc
    23941 ccgacgccct cggccgggcg gtgacggagc tgggcgagcg gtcgggcgcg acccccttca
    24001 tgacgctgct cggcgcgttc caggtgctgc tgcaccacta cacgggccgt acggacatcg
    24061 cggtgggcgt tcccgtcgcc gcgcggaccc gggaggagac ggaggggctg ctcggcctct
    24121 tcgtgaacag cctggtcatc cgtacggacc tgggcgggga cccggccttc accgggctgc
    24181 tggagcaagt gaagcgggtc tgcctggagg cgttcgccca ccaggacgtc ccgttcgagc
    24241 ggctcgtgga cgagctggcg accgaccgcg acctctcccg caacccgctg ttccaggtga
    24301 tgttcgagca ccagcacatg ggcgggctca cctccacgct cggcggtctg gcggccgaac
    24361 cgctcaacgc cggtccgcag accgccaagt tcgacctgac gctgaccgtg aaggaacgtc
    24421 cggacggacg gatgcactgc tggttcgagt acgcgagcgc gctcttcgac cgctccacgg
    24481 tggagcggat ggccacccac tacctgcgcc tgctggaatc ggtgaccgcg gcgcccgaca
    24541 cggccgtggc cggtctcgac ctgatgtcgg acgccgagcg ccggcagctg ctggacgtct
    24601 ggcccgaccc ggacgccgcc cggctgccgg agatcgttcc cgaggacgag agcgggctga
    24661 ccgtgccgga gctgttcgtc cggcaggccg cccgcacccc ggacgccacc gccctggtct
    24721 tcggcgggga ggagctggac tacgccgccc tggaggcccg ctccgcccgc ttcgcccggc
    24781 gtctgcgcgc cctgggggcg ggtcccgaga cggcggtggc ctcctgccag gaacgcggca
    24841 tcgacgccgt ggtcaccctc ctcggtgtgc tgcgggcggg cgcggtctac gtaccgctgg
    24901 acccccgcca cccccggcag cgcctgctgc ggaccgtcga ggacgccggg gcccggttcc
    24961 tggtcaccac gtccgggcac gcggagaccc tcaccggcgc cggccatcag gtgctcaccg
    25021 tggacgccct ggtcgccgaa ggcgccgaag gggagctgcc ggacgttccg gcggacccgg
    25081 agaacctggc ctatgtgatc tacacctccg gctccaccgg gcgccccaag ggggtgatga
    25141 tcgaccaccg cgcctacgcc caccactgcc gcgtcgccgc cgacgcgtac gggatcggcc
    25201 ccggtgaacg ggtggtccag ctctcctcgc tgaccttcga cgtgtcgatg gagcagatcg
    25261 ccgccccgct gctgaccggt gccgccgtgg tgatagccga cccgctgttc tggagcccgg
    25321 ccgaactccc cgcccggctg gccgaacacg gtgtcacggt catggagacc accccggcct
    25381 actaccggga ggccatgaac tacgacacga gcgtgctcac cgggctgaag ctgatcaacc
    25441 tcagcagcga cgtggtcacc gtggccgacg cccggcagtg ggccgcgagc gggctgcccg
    25501 gccgcttcgt ctgctgctac ggccccacgg aggcgaccgt cacctgcctg ctgcacaccg
    25561 gcccggccgg gcagggcggg gaacgggaca ccgcctccat gccgctgggc cgccccttcg
    25621 ccggcacccg ggcgtacgtc ctggacgccg ggcagcgccc cgtaccgatc ggtgtgcccg
    25681 gcgagctctg cgtcggtggc gtccggctgg cccgcggcta ccacgggcgc ccggagctga
    25741 ccgccgcaca gttcgtgccc gacccgttcg gcggtgcggg cgagcggttg taccgcaccg
    25801 gtgacctggt gcgctaccgg ccggacggca ccctggagtt cctgggccgg atcgaccagc
    25861 aggtgaagat ccgcgggctg cgcatcgagc tgggggagat cgaggcggcc ctcaccggtc
    25921 atcccggcgt cggcgcgtcg gcggtgaccg cgcccgagat cgccccgggc gaccgccggc
    25981 tggccgccta tgtgaccggc ctggacggcg cccccgcccc ggacccggag acgctccggg
    26041 agcatctgcg ggaggggctg cccgactaca tggtcccggc gctgtggacc gtgctggact
    26101 ccctgccgat gaccgccagc cagaagatcg accgcaaggc cctgcccgcc cccgccacca
    26161 cgctcgaacg cgcctacgtg gcgccccggg acccggtcga ggaggccgtc gccgcgatct
    26221 gggcggaggc gctcggggtc gaccgggtcg gtgccgagga cgacttcttc gccctgggcg
    26281 ggcactcgct gctggccacc cgggtcctgg cccggctgag ggaggccttc gcggtggagc
    26341 tcccgctgcg ccgcctcttc gaacacacca ccgtcaccgc cctcgcggcg gccgtcaccg
    26401 aggccgtcga ggccgctatc gcccagctct ccgacgcaga ggtcgcggaa ctgctgaacc
    26461 cggaaggcgc acgatgacgc accagacact cgaccccgcg gacctccgcg cccgcctgct
    26521 ccggcagcgg ctgcgcggca cggccgcccc tgccccgtcc gacggcatcc cccgcgccgg
    26581 gcgcggcggg ccgctgccgc tctcctccgc ccagcagcgg ctctgggtgc tggaccggct
    26641 gagccccggc tccaccacct acctcatgac ggccgcgctg cggctgcgcg gacctctggc
    26701 ccccgaggcg ctgcggggtg cgctggaggc cctggtgacc cggcacgagg tgctgcgcac
    26761 ccgctacgag gtcgtcgacg gcgatccggt ccagatcgtg gacgcgcccg ccccggtgga
    26821 tctcgtcgag gaggatctga ccgggctgga cccggcggac cgcgcgcgcc ggctgaccgc
    26881 gctgggcacc tcggggcgcc ggccggtgga cctggccgag ggacccgtgt tccgggccgt
    26941 cctggcccgc tgctcggccg aggaacacgc tctcttcctg accgtgcacc acatcgcggc
    27001 ggacggccgg tcggaagagc tgatggtgcg tgagctgatg gcccactacc gccggtcgac
    27061 cgctggagag acgcatccgg accctgcccc gccggccctc cagtacgcgg acttcgccgt
    27121 ctggcagcgg tcccggctca ccgaggagag gctccgggcg ggcctcgacc actggcgcgg
    27181 gcggctggcg gggctcacgc cactggagct gccgaccgac cggccgcggc ccgcggtccg
    27241 cgacgagcgc ggtgccgtgg cccccttcac cgtgcccgcc gaggtggccg gccggctctc
    27301 ccggctggcc cgcgagcggg gcgccacccc gttcatggcc gctctcgccg cgttccaggt
    27361 gctgctcggc cggtacgcgg gcagcaccga catcgccgtc ggcacccccg tgtccggccg
    27421 ggacaggacc gagacccagg acatgctggg gctcttcctc aacaccctgg tcctgcgcac
    27481 cgatctctcg ggagcccccg gcttcggcga ggtactgaac cgggtgcggg agggctcgct
    27541 ggacgactac ggccaccagg aggtgccctt cgaacggctg gtggacgcgc tggctcccga
    27601 gcgcgatccc tcccgtacgc cgttgttcgg cgccatgttc ctctgggacg gcgccgacgg
    27661 cccttcctcg gaggcgcacg ccgggggtgc ggattcgctc gtggtggagc ggctcgcggt
    27721 cggtgagtcg accgccaagt tcgatctgac gctcagtgtc gccgaacagc cggacggttc
    27781 gctctccggc gggctcaact acgcgaccgc gctgttcgac gcggcgacgg ccgcccgcat
    27841 ggccgaccac ttcgtccggc tgctcaccgc cgccgtggcc gagcccgacg tcccggtggc
    27901 cgaactggag ctgatgtccc cggcggagct ggagcaggtg gtccaccgct ggaacgagac
    27961 cgacgtcccg ttccccaccg gcacgctgca cgggctgttc gaggcccagg ccgcggcgac
    28021 cccggaggcg gtggcggtgg ccgacgagga cggcacgctc ggctacgggg agctggaccg
    28081 ccgcgcggag gcggtggccg acgcgctgag ggcccggggc gccggtcccg gcaccgtgac
    28141 cggggtgtgc ctggagcgct cccgggggct gctggtggcc ctcctcggtg tgctcaaggc
    28201 gggcagcgcc tacctcccgc tggagccgga tctccctgcg gagcgccgcc ggtacatgct
    28261 gtccgactcc ggcgcccggg tcgtgctcac cgacaccggg gccggcccgg acggcgtgcc
    28321 ggaggaggtc gccgtcgtgc ccctggcacg cggcggaatg ctgcccgacg gggcgccggc
    28381 cctgcccgga ggctcctccg gcccggacga cgccgcgtac ctcatctaca cctccgggtc
    28441 caccggccgc cccaaggggg tgctggtgga gcaccgggcg atcgtaaacc ggctgcactg
    28501 gatgcagcgg gagttcgggc tcgacgccac cgaccgggtg ctccagaaga cgccgatggg
    28561 cttcgacgtc tcggtctggg agttcttctg gccggtgatc acgggcgcca ccctggtgat
    28621 ggcgcgcccc ggaggccacc gggatccggc gtacctcgcc cggaccatcg ccgagcggtc
    28681 catcaccacc ctgcacttcg tcccgtcgat gctgcgcgcg ttcctcgcgg gccccgtgcc
    28741 ggcgctgccc tcggtgcggc gcgtcgtctg cagcggggag gcgctgcccg gcgacctggt
    28801 caccgcggcg gtggagcgcc tggggaccgc cccgcacaac ctctacggcc cgaccgaggc
    28861 ggccgtggac gtcacccacg ccccctgcgt ccccggacgg cgcgtcacca tcggcaggcc
    28921 catcgccaac acccgtacct acatcgtgga cgcggccctg cggcccgtcc cggtcggggt
    28981 cccgggagag ctgctgctgg gcggtgtcca gctggcccgg ggctacccgg gccggcccgc
    29041 gctgaccgcc gaccggttcg tccccgaccc cttcggcggg gagccgggcg ggcggctcta
    29101 ccgcaccggt gacctggccc ggtatctgcc ggacggcacc atcgactacc tgggccggat
    29161 ggaccaccag gtgaagatcc gcggccagcg catcgagctg ggcgagatcg aggcggtcct
    29221 gcacgagcac ccctcggtca gcgccgcggc cgtcacggtg cacgacgggc ggctggtggc
    29281 ccacctcgtc ggccacccct cgccggagga cggcgctccg gacaccgacg ccgtacggac
    29341 ctggcttcgc gagcggctgc cggacgccat ggtgcccggc gactggacgg tgctcgacgc
    29401 cctgccgctg acggcgagcg gcaagaccga ccgcaaggcg ctgcccgccc cggaccgcag
    29461 ccgggagagc cgggccggtg agtacaccgc gccccgcacc ccggtggagc ggaccatagc
    29521 cgaggagctg gccgccgcgc tggacctcga ccgggtgggt gtccacgacc ggttcttcga
    29581 cctgggcggc gactccatcc gggcgatccg cgcggtgggc gcgctgacgg cccgcggcct
    29641 ggccctgtcc gtgcagcacc tcttcaccca ccccaccgcc gcccggctcg ccaccgtcgc
    29701 caccgagacc accggcaccg ggcaggggcc cgagctggtc gccccgttcg cccagctggc
    29761 cccggccgac ctcgaacggc taccggacgg actggccgac gcctatccgc tgggcgaggt
    29821 ccaggccggg atggtctacg agctgctggc cgatccggac gccaacacgt accagaacgt
    29881 cagcagtttc cacttcaccg acgacggccc cttcgacctg ccggcgctgc gggaggcggt
    29941 ccggcgtctc gtcgaccggc acgagatcct ccgcacctcc ttccggctct ccggcttctc
    30001 cggaccgctc cagctcgtgc acgagaaggc cggggcggag gtcgggttca ccgatctgcg
    30061 ggagctggac ccggccggac agcgcgccgc catcgcggag ttccgcgccg ccgagcagcg
    30121 cctgccgttc gatctggaac gcgccccgct gctccgctac cacgtgcacc gcaccggtga
    30181 acgcacctgg acgctcaccc acacggagtg ccacgcgatc ctggacggct ggagccacca
    30241 ctcggtgatc caggagatcc gcgccgacta cggccgtatc cgcgaggacg ccgactgcgc
    30301 cgtcacgccc ccgccgcggg cccgctacgc cgacttcatc gccctggaac agcgggcgct
    30361 ggagtcctcg gaggaccggg cgttctggca gagcaggatc gacggcttcc cgcgcctgga
    30421 actgcccgcg cccaccgcgc ccgcggaggc cgacgggccc gcccacgagg tccgggtctc
    30481 ctgggccgga ctggatccgg agctgcgcgc cctggccgcc cgtaccggca cctcgctcaa
    30541 gacggtgctc tacaccgccc atctcacgct gctgggcctg atctccggac agcgccgctt
    30601 cttcgccgga gccgtctgca acggccgccc cgaactcccg gacggcgacg aggtgcgcgg
    30661 catgtacctc aacaccgtgc cgttcgcggt cgatctgcga gcgccgagct gggaggagct
    30721 gctgcgcgcc gtcttcgcgg aggaggccgc cgtctggccg caccgccggt acccgctgcc
    30781 cgccatgcag cgggagtggg gcgcgggggt gccgctggtc gacgtgatct tcggctatct
    30841 cgacttccat gtgctggacc agtccggctc cgcccccgag gcggtcaccg acagcagccc
    30901 caacgagttc accttcgacg tgtggacctt cccgggcgag ctgcggatga cctgccgtcc
    30961 gggctgggcc gaccgggccc ggctggagac gatggccgcc gccttcgtgg aggtgctgcg
    31021 gaccatggcc gagcggccgg actcctcccc ggcgtccttc cgcgccaccg gactgaccgg
    31081 agacgcggcc ggtgcggtgc cccgccggct gccgcccgag gtgacgctgc cggaactgat
    31141 cggccggggc gccgacccgg aggccgtggc gctggtcgac aggggatcgg ccgtgacgta
    31201 cgggcagttg gaggagcggg ccaaccggtt cgcccggttg ctgcgggccc gcggggtgcg
    31261 cgccgaggat cccgtcgcgg tctgcctgga gcgcggcgcg gagacggtgg tcgccctcct
    31321 cggcgtcgtc aaggcgggcg gctgctacgt cccggtcgac ccggagtacc ccgaggagcg
    31381 gatcggctat ctgctctccg actccggtgc ccggctgctg gtcacccgct ccgacctggc
    31441 cggccggctc cccgggaacg taccgacggt gctcctggac atcgcgcggg acgagctgga
    31501 ggcgcagtcg cccaccgccc cggagacggg cgtctccccc gacaacaccg cgtacgtcat
    31561 ctacacctcc ggatccaccg gccgccccaa gggcgtccag atcacccacc gcaatgtggt
    31621 gcgtctggtg cacgacgaga accacgcggc gatcgggccg cgggacaccg tcctggtggt
    31681 ctctccgctg gccttcgacg cctccgcctt cgaactgtgg ggcacgctcg ccaacggagg
    31741 ccggctggcc ttcgccccgc ccggcactcc caccaccgcg ggcatcgccg aggtgctgcg
    31801 cgagcacggg gtgaccgtgg cgttcctgac gaccagcctg ttccatctga tggtggagag
    31861 ctgcccggac gcgctgacgg gtctgcgtac gctgctgacc ggcggggacg tgctctccgc
    31921 cggacgggtg cgtgccgcgc tcggccacgg gctgcgggtg agcaacatgt acgggccgac
    31981 cgagtgcacc accttcgcca ccgggcagca cgcgatcacc ctggagcaga cggaccggcc
    32041 gatccccatc ggcctgccga tcgcgcacac caccgcgctg gtcaccgacg aggacctcgt
    32101 acccgttccg tacggtgtcg ccggcgaact gctgctcggc ggtcccgggg tggcccgtgg
    32161 ctatctgggc cgcccggagc tgaccgccga ccggttcgtg cccgacccca ccggcacctg
    32221 gcccggtggc aggctctacc gcaccggcga cctggtgcgc caggacccgg acggcgtcct
    32281 gcacttcctg ggccgccgcg accaccaggt caaggtgcgc ggccaccgta tcgagctggg
    32341 cgaggtcgag gcggggctga gcggcctgcc gggtgtgcac gaggcggcgg cggccgtgcg
    32401 tccgggcccg gacggcgaca agcagctcgt cggctacatc gttccggagg agcacagcgg
    32461 tttcgacccg gcgctcctgc gagccgcgct ccgcgcgaag gtgcccggct tcctggtgcc
    32521 cagcgcctgg gtccggctgg aggagctgcc gctcaacgcc aacgggaagc tggaccgcgc
    32581 ggcgctcccg gcgccggacg gcggcaccgc cggcgaggtg gtcgccccgc gcaccgcggc
    32641 cgaacgggcg ctggccgagg tgtgggcgga ggtcctcaac ctcgaacagg tgggagtcca
    32701 cgacgacttc ttcctgctcg gcgggcactc cctgctgatt ctgcgggcca tcgcgctgct
    32761 ccgggaacgc cacggcctgg agctgaccgt acgggccttc gtggagcacc acaccctgga
    32821 cgccatcgcc gccgcggcgg agcgcggcga ctacggggac acctcgcgca ccgccctgat
    32881 gtggctgcgc gccgagggtg accgggcgcc gctcttctgc gtccaccccg gcggcggcag
    32941 cgcccactgg taccagcggc tgcttccgca cctggcgccg gatctgccgg tcgccgccct
    33001 ggagtggccc ggcctccagt ccggaccggg gctgccggtg cccaccgcct cggagatggc
    33061 ccagcggtac gtcgccgaga tccgcgcggc ccgtccgcac ggcccgtacc gcctgctggg
    33121 ctggtgcggc ggcagcggta tcaccgccga gatggcggac cggctgcggg cggacgggga
    33181 ggaggtgacg ttcgtcctgc tcgatccggg cctggacagc cacgaacggc agggcctgtg
    33241 ggaggagttc cggctgatcg agagctgcac cgccaagctg gaggagctgg ccgccgccgg
    33301 cccggaggag gacacgggtg cgctccgcga ggagatcctg aagctgctgg accacctggt
    33361 ggacgatgcc gacccggaga ccgggatcgt gctccccgag cacaacgggg ccgatgtctg
    33421 gcttccgtcg gcccggatct ggcgcgaggt gatggagatg accctcacct accggcacca
    33481 ccacgtcccc ggcacgctgc atctggtcat cagcgacgaa ctcgcccgcg gggagcacga
    33541 ggtggccctc ggccagtcgt acgaggagta cctgagccgc tggcgggagc tgaactccgg
    33601 agtcgaggtc caccgggtcc ccggcgacca cttcggcgtc atgcgcctgc cccacgtcac
    33661 ctccctggcc tcgaccctgg cctcggtgct ggactgaccg tcccggagag gagaccggac
    33721 agagcccggc cggagcatgc gctccggccg ggctctgtgc tgtcgtccgt ggggggctcg
    33781 gggcccggga ggggcgaggg ggcgcgaggc gggagggccc tgggagggaa agcccccggc
    33841 aggggaggga agcccccagg ggggaggcgg aggcccagga gggtggctcc cgatcggccg
    33901 acgagcgggc cggcctcagc tatccgccct cgcccacaag ccgggctgtg tccccggacc
    33961 ccggtccccc ggtcggcctg ggccctggcg tctcgccggt acgcgccccc aggccctgcc
    34021 cgtccgtgtg cccggacacg acgacggggt gcccggccgg tgcggccgga caccccgtgc
    34081 gagggtcttc ggtgttctca gtcgtgctgg tcgacggcga cgaagcggag ttcggaggtg
    34141 taggcgttgc cccggtcgtc ggtcagccac gcgtgctcgg gactcggcag catctccgtg
    34201 atcgtgagct tcgcctccgg atccttccgc gccagccgac gagccgcctt cgccaggatg
    34261 ttcacataca ccggagcatc gaaatccaca tagaacggac gcggctccgt cggcgacacc
    34321 acgaacacat accgaggcaa cccccgctca ccacgccagt tccgcgcccg cacataccgc
    34381 cgggcctcac tcttctcctc cgcgaacccc aactccccac ccgtgaaccg ccacgactca
    34441 cggctcacca ccagcttgtc caccatcacc cgcggcacat gatccgcgtc ggggaacagc
    34501 cggaacaggt ccatggccag ggtggtcagc acatggccga acacatcggt gacggggaac
    34561 tccgctcccc cgggcaggac gacgaccggt cggccgtcgc gcaggacgac gtgggcgtcc
    34621 gcgctgagca cggtgcggtc ccggtgcggg tctgcggtga gctccatcag cgcgacgtag
    34681 tagtcctccg gccggaccag cacgttgcgc acccgggtcg agagccgtgc cttgtgctcc
    34741 ttgggcagca ggggcagcag ccgggggccg gggtggtccc ggccggtgag ccggaggagt
    34801 tccgccggct cggggtgctg gctgacgaac agcgaggcgc ccatggtgtt ggaggccagg
    34861 tgcagttcgc cgaggacgag ttcgaagtcg cccctgccga tcgcctcggt gtcgcgggcg
    34921 gcgatcagca catcggggct gaggtagcgg gcggcggtcc aggcgaccgg gaccgggggg
    34981 aacgcctcgg ccacctggga cgcgacggcc gagtgggtcg cccgcacccg cgcctccccc
    35041 tccggcagcg ggatgatccg cgcccagcgg cgctggaact ccgccagcac ctcctgtgcg
    35101 tcggtgaccg cgtcgccgtg caggatcggc atggaggcga accagaagtc ggcgaggttg
    35161 acccgttcct caccggaggc ggcggacagc ttctcgtaga cctctacggc ccgctgctcc
    35221 acccgggcgc cgagccggcc catgagccac gcggcgctgg tcatcagcgg gtccaggggc
    35281 gccatggcgt ccaggacggt gccgccgatc cgggcggtgg cggagcggcg ggtgtcggag
    35341 tggaccagcg accggttcgg tgccgtaccg ctgcccttgg cccgctggga cgcggtgtcg
    35401 gtgatccggg tgaagtcctc ctccagcgcg gccagcgcct cgcacaacgc ctccgcgtca
    35461 cgcccggccg cctccacccg ctcacggccc cgctccagaa cctccaacgg ctccagcgca
    35521 ccacgccgca gctccgcgtc ccccacccgc tccagaaccg cacgcagctc ccggtccgga
    35581 cgcgcacccg aaggcacctc caaccgccag ctcacccacc gacgacgcac cagctcggtg
    35641 agccgggagg tgacctcgtc gagtgatgtg ccgaggatcc gggcgagttc gtgcggtgag
    35701 cggcgaccgt ccgcgagccg gagcagagcc accagatggg gcggcgcctg ctgggggcgg
    35761 cggccgggga cgtggacggg gccctcgtgg gactcggcgc ggatgtaggg cagccgtcgt
    35821 gggggtatcc aggccatcag ccgctcgtcc gccgacaacg tcctcgccag cgcatcgatc
    35881 gaccaactcg agaagaacac cgacgacgac gccgtcaacc cctcccccgg atcaacctcc
    35941 acacccccca ccgaaccatc cacacgaccc cagcccaccg gaccgaaaaa cccgatcgtg
    36001 tcattcttca cacagaaacg ctgccaataa tgcgccacca actcctcacg ctgacgcggc
    36061 atactcgacc gacccgacgc cgaaggcacc caccccagaa acggccgcaa acccgtccgc
    36121 aacaccgtcc ggttctgcca cgccaccgcc gcagtgaaat ccgaagaacc cgcaacaccc
    36181 tgcaacctca ccgcagtacg cgccgcaacc tccccgaaca ccccctcgaa ctcctcccaa
    36241 tcaggacccg acaacacccc accagcaaac ttgtccgcat acaccgacac atccaccgga
    36301 gccagatcca acacaccccc caccggaaaa cccggcccac gcaacgaaaa ctgctcccac
    36361 aaccgccaac g
//
