LOCUS       NZ_ARPF01000003        22763 bp    DNA     linear   CON 18-FEB-2024
DEFINITION  Streptomyces sp. SolWspMP-sol2th B083DRAFT_scaffold_2.3_C, whole
            genome shotgun sequence.
ACCESSION   NZ_ARPF01000003
VERSION     NZ_ARPF01000003.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. SolWspMP-sol2th
  ORGANISM  Streptomyces sp. SolWspMP-sol2th
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 613328)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Improved High-Quality Draft of Streptomyces sp. SolWspMP-sol2th
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 613328)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces sp. SolWspMP-sol2th
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/18/2024 03:17:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,475
            CDSs (total)                      :: 6,400
            Genes (coding)                    :: 6,297
            CDSs (with protein)               :: 6,297
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 31 of 103
            Pseudo Genes (incomplete)         :: 82 of 103
            Pseudo Genes (internal stop)      :: 12 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:24:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 104863
            Orig. end                         :: 127626
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ARPF01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..22763
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22763
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22763
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12763](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12763
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    301..312
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    772..781
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    1034..1049
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    1170..1185
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.19"
                     /tool="antismash"
     misc_feature    1173..1186
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.12"
                     /tool="antismash"
     misc_feature    complement(1173..1188)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.78"
                     /tool="antismash"
     gene            1260..1454
                     /locus_tag="B083_RS0107215"
     CDS             1260..1454
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190440.1"
                     /locus_tag="B083_RS0107215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018490263.1"
                     /transl_table=11
                     /translation="MALSISAVVLLAIIVFLLIRKSGLKGGHAVICMLLGFYIASSSVA
                     PTISDLTSNVAGMIGSIKF"
     gene            1583..2650
                     /gene="mshB"
                     /locus_tag="B083_RS0107220"
     CDS             1583..2650
                     /EC_number="3.5.1.103"
                     /GO_process="GO:0010125 - mycothiol biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mshB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845650.1"
                     /locus_tag="B083_RS0107220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-
                     D-glucopyranoside deacetylase"
                     /protein_id="WP_028416219.1"
                     /sec_met_domain="PIG-L (E-value: 4.5e-27, bitscore: 90.3,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLPARRLLLVHAHPDDESINNGATMARYAAEGAHVTLVTCTLG
                     EEGEVIPPALAHLAADRDDTLGPYRVGELAAAMKELGVTDHRFLGGPGRFRDSGMMGTE
                     QNERPGAFWATPVDEAAAPLVEIIREVRPQVLVTYDPDGGYGHPDHIQAHRVAMRATGL
                     AADPAYGTGAPHTVAKVYWNRAERPVVEAAFAHLRATAPDAFPGIAAVDDVPGVVDGDG
                     ITAEIDGSAYAGAKAAAMRAHATQIALADEGPFFALSNDLGQPLLTTEYYQLVRGVPAA
                     GTGAREDDLFAGVTEAETASAPEPGTGADAVRGVAPGPGTEAGADAVRGPVSGSASGVG
                     PDSVSGPASGSGAGA"
     misc_feature    complement(1617..1630)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.32"
                     /tool="antismash"
     gene            2809..3270
                     /locus_tag="B083_RS0107225"
     CDS             2809..3270
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572733.1"
                     /locus_tag="B083_RS0107225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6113 family protein"
                     /protein_id="WP_028416220.1"
                     /transl_table=11
                     /translation="MPGSGEAASRTGTPRTGTPPQVPAGVGFTGRPNPARIAAYFGLAV
                     LGALVALAGTLLQAAWFPGGLIIALAGSAGLFYGGRILTGTQIGALAPAVGWFVTVFLL
                     LSGRPEGDYVFGDELGLALFMLGGTAVAVMCATTSKVPQSATPRGRSGI"
     gene            3446..5719
                     /locus_tag="B083_RS0107230"
     CDS             3446..5719
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611145.1"
                     /locus_tag="B083_RS0107230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_198537048.1"
                     /transl_table=11
                     /translation="MSRETDSSSSGPQGRGGAAYPSGTPPYGSRQYSSAAGSDESPESV
                     DPPRPEEPKTETTLTTRIRINIPGSRPIPPVVMRTPMAESDLATGRPDAERTGSTPRPG
                     TPPAAPSGLTGGAAAASSAAQARDARGAGDGGGSADPSASSASGPAAAEEGAKAKTGSD
                     WFAPRKSPAPAPAPASGSAGMPGSGSTGAGPLGSGGPGASGPDGGTRPRPDLPYFSDAD
                     PRPGGGPGAPGSGIPGPDTPGSGIPGLGVPASALDGYSAEAPGGGPRSTTDPGVHAHGP
                     GRPGGPGPAGPTTGPVTGTSSLTPDLDGIPGLGGPGPMVPGAPGGVPPRLSDDTAILTP
                     QSPAPDTGPGGHVSGDTLTSGIPVVPSEPRSTFPGGPDGPGGAFPGGPGSGGGPFPGGP
                     GGSGSPFPGGNDPFADGPDGPGAAKTPRPAAARPAPTPAPPARKGRSKLVLLGVAAVVL
                     LGIAYGAGLLLNHSEVPKGTTVLGVDIGGGTKEEAVVKLDAALGERSRAPLSLSVDGKE
                     EKLDPEKAGLTLDSQETVRGAAGSDYNPVSVIGSLFGGARTADPVIPVDEEKLGVALND
                     LAGTAGSSQDGTIRFEPNKAIAVPGKPGKTLDVGQSLISVRDAYRAQVQTGRPKVVELP
                     VATREPTITQAELTRAMKEFAEPAMSDLITIKAGPKQIQFGPARSLPQILSMKAVDGRL
                     VDVYDKKAITTLLDGVFDGITAVKADGKQHPVGADDVAQAMKTALTGKTPAERTVTIDL
                     TGEG"
     gene            complement(5946..7757)
                     /locus_tag="B083_RS0107235"
     CDS             complement(5946..7757)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154253.1"
                     /locus_tag="B083_RS0107235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028416542.1"
                     /transl_table=11
                     /translation="MPVPPTAPHSGAAPRGRRRSRALGFAALAVSLLMAVPTAQTAFGE
                     EARDGQEIQAVPGGGDLGPNVHVFDPSTPGIQGKVDEIFRKQESAQFGLDRHALLFKPG
                     TYDDINAQIGFYTSIAGLGLHPNDTTFNGDVTVDAGWFDGNATQNFWRSAENLTLNPVN
                     GTNRWAVSQAAPFRRMHVKGGLNLAPDGYGWASGGYIADSKIDGEVGPYSQQQWYTRDS
                     SVGGWTNGVWNMTFSGVEGAPANSFPEPPYTTLDTTPISREKPFLYLDGDDYKVFVPQK
                     RENARGVSWADGTPPGESIPLDQFYVVKEGADAATINAAVEQGLHLLFTPGVYHVDETI
                     TIDRPDTVALGIGLATIIPDNGVTAIKVGDVDGVKLAGLLVDAGPVNSETLIEVGPQGA
                     SADHAANPTSLQDVFVRIGGAGPGKATTSIVVNSDDVIIDHTWVWRADHGEGWGWETNR
                     ADYGVRVNGDDVLATGLFVEHFNKYDVEWYGERGRTIFFQNEKAYDAPNQEAIQNGDTK
                     GYAAYRVDDSVEQHEGWGLGSYCYYNVDPTIVQEHGFKAPVKPGVKFHHLIVVSLGGNG
                     QFEHVINDIGAPTSGTETVPSQVVNFP"
     misc_feature    7843..7860
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.97"
                     /tool="antismash"
     gene            8022..8549
                     /locus_tag="B083_RS01000000133045"
     CDS             8022..8549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="B083_RS01000000133045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_032754954.1"
                     /transl_table=11
                     /translation="MSSLDAGAPRPARDDPPPPGVGRRIKVWFRFVPREDWLPYDTEGL
                     WATRLSADTARVDNVPFLQDGVAEGETVRFTTDADGVHWATGRVADSGNCTVRVLPVPD
                     GPLGRDARAVHERFSPFGLGGEVFSADFPLVALTVPGGADFRAIKALLVRGQDEGWWHF
                     EVGCATEAWRRA"
     gene            complement(8789..9361)
                     /locus_tag="B083_RS0107245"
     CDS             complement(8789..9361)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489199.1"
                     /locus_tag="B083_RS0107245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_050451250.1"
                     /sec_met_domain="Mac (E-value: 5.7e-15, bitscore: 50.3,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAGELYLADDPEIAADALRSALLTERFNATSAADPEARRAALAE
                     LLGELGEGAEIRPPLRVDYGHQITVGPRTFVNFGAVFLDVARITIGADVQIGPNVQLLT
                     PTHPIDPEPRRAKWEAAEPITIGDNVWLGGGVIVCPGVSIGENTVVGAGAVVTKDLPAN
                     VVAVGNPARVIRKIGEEGDGKAPAPTA"
     misc_feature    complement(9551..9570)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.66"
                     /tool="antismash"
     misc_feature    9666..9680
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.15"
                     /tool="antismash"
     misc_feature    9949..9963
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.56"
                     /tool="antismash"
     misc_feature    9954..9969
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            10001..12763
                     /gene="lanKC"
                     /locus_tag="B083_RS0107250"
     CDS             10001..12763
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489198.1"
                     /locus_tag="B083_RS0107250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_028416223.1"
                     /sec_met_domain="micKC (E-value: 1.2e-220, bitscore: 729.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.5e-11, bitscore: 38.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-06, bitscore:
                     22.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRRFYDAPHRSLEAGAEERTFYAPVRGGAPEGWT
                     RSRRGDWLSFSPDGLRLPAQGWKLHITAAADNAESVLERVAAHCLARRLPFKCIPSPAL
                     LALRNSKYADRAGSGKFITVYPHSEETFPEVCAALMELLEGEHGPYILSDLRCGDGPVH
                     TRYGAFAARFCTGPDGRPVPAVADPQGRLVPDDRGPAFRVPAWVTPPDFLRPHLEARAA
                     VGLGDLPYTVEKALHFSNGGGVYFGRDSRTGEQVVLKEARPYAGLAADGADAVARLERE
                     RTALERLEGLECVPAVRDAFEVGGHHFLVLQYLPGTTLNTVFARRFPLARQNPAPELLA
                     GHVAWAEEVYGKVERAVEAVHARGIVISDLHMSNVMVDEESGRIALLDFEAASPAADRR
                     RQIVANPAFVAPPDRRGTDIDRYALACLRLALYLPLTTLFGIDRMKAAGLAREIARVFP
                     VGEERLRPAVEEIQRGAEAAGTDTGASSRRNPASPADLASRTDASTGTGAGAGAGTAPG
                     ADASRTLPPDPGDWPESRAAMARAIAASCTPDRDDRCFPGDIAQFATATGGQSFAYGAA
                     GVLYALHETGAPRCEPAEEWLVRQAKDPASGSPLGFYDGLTGIAWTLNRIGRTAEAADL
                     VRIVLDQPLEGLAPGLHSGYAGIGLALDDLARTAPATEAPALAAAAGRCTALAVRALVD
                     GPPSPRTGLLHGATGVALLLIRRYATTGDPALLDVAAAALRRDLDRCRAGDDGELLVVE
                     GKRLMPYLGAGSAGIAAVIDAYLAHRPGDAELEAAGRALLPAALSAFYVQPGLLRGSAG
                     LLMHLAATPLCDAETRERAIRLHTRLLAGHALTYGGGLAFPGEQLMRLSMDLATGTAGC
                     LLALGAALGTAPGAPPGPATTLPFLAATVPPVARPGRASGPTDRLLQGS"
     misc_feature    complement(12780..12800)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            12833..12964
                     /locus_tag="B083_RS0107255"
     CDS             12833..12964
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="B083_RS0107255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_015611153.1"
                     /transl_table=11
                     /translation="MALLDLQAMETPAEESFGELATGSQVSLLVCEYSSLSVVLCTP"
     CDS_motif       12833..12898
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMETPAEESFGELAT"
                     /locus_tag="B083_RS0107255_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12899..12964
                     /prepeptide="core"
                     /locus_tag="B083_RS0107255_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="31.50"
                     /molecular_weight="2076.4"
                     /monoisotopic_mass="2075.1"
                     /core_sequence="GSQVSLLVCEYSSLSVVLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMETPAEESFGELAT"
                     /leader_location="[12832:12898](+)"
                     /alternative_weights="2094.4"
                     /alternative_weights="2112.4"
                     /alternative_weights="2130.5"
                     /alternative_weights="2148.5"
     gene            13112..15004
                     /locus_tag="B083_RS0107260"
     CDS             13112..15004
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489197.1"
                     /locus_tag="B083_RS0107260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_028416224.1"
                     /transl_table=11
                     /translation="MRPKPRPRLRPPAPSGARRLARRHPGALLALFLCSTGGALAALAL
                     PAALGHTVDRLVDGGAVPWAGLLLCAVLTLAETGFDAGAAVLTTSTGARLTAHLRTRTT
                     ARVLAAEPRRALAVPTGDLTARLTARTADAATAPVTAAGAVAGVLLPLGAIVGLFVIDP
                     WTAAAFLLGAPLLVALLHTFTRRTADAGADYQRAQSVIAHRLTEALDGADTIRAARTGA
                     REYRRILEPLTTLAAHGRRTWTVYGRAAGQSALLLPLLMLLVLAVGGLRLQAGAIGVGD
                     LVAASRYAALAVGIGSLTGALGALARSRAAARTLDPLLTLDPLPHEGLGPPHGGPGHLE
                     LRDVGVVQDGKRQDVQGGKQGGKQEDEQGGEALPDGEPDRKPLLTGVHLTVPGGTSLAV
                     VGRSGSGKSVFAAVVGRLLDPDTGTVLLDGIPLTAMEPARLRPEIAYAFARPALPGTTV
                     EDTIAFGPWTAGPAAVREGARAARADGFVGLLPYGYATPLTDAPLSGGERQRLGLARAF
                     AHPGRLLILDDALSGLDTVTEHHVRRALDERAGRCTRVIVAHRLSSAARADQVLWLEDG
                     RVRATGPHEELWADPEYRAVFRTETGEAEEMAEADEGPGAEGALPRARTEVEAR"
     gene            15001..17100
                     /locus_tag="B083_RS0107265"
     CDS             15001..17100
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489196.1"
                     /locus_tag="B083_RS0107265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_028416225.1"
                     /transl_table=11
                     /translation="MKAPRTARPPGPLTRVTRDARPFLRARTGTVLRLGGWSLLEFVQT
                     FLGGYGVARALDHGFLAGRPLTGLLWLAVAAVAVLPAQLATRGVFGRLADLVEPLRDGL
                     VRRAVSRALVGALEHPTGTTARSLSQVTHQSEIARDGWAGLVLTLRSFVFTVAGAVAGL
                     LALEPRLLLLVLPPLVLGAGLFLATLVPMAARQRDYLTADEAYAAHAGRTAADLRDIAA
                     AGAAARTVTESGELADAQVRAARSLARWSGVRVVALAVCGRFPPLLLLLGAPWLLRDGL
                     TPGALVGALTYLTQALAPAVQALMTMLSTVGGRLLVVLDRFTDAPPPPAEDGDDGRAHG
                     HGQGHSRGLDGHDRGAPTPRHAPVAELDTVTFAYGPAARPVLDRLSLTVAPGEHLAVVG
                     PSGSGKSTLAAVLAGVETPGAGSVRWLGRPVRAADATSVRVLLPQHAYVFTGSLRDNLR
                     YLCPDATDRELAATVDALGLDPLLTRLGSLDALVEPDRLSQGERQLVALGRAHLAAPPL
                     IVLDEATSRLDPAAETRAEEAFAALPSALVVVAHRLSSAHRADRILVMDGPRTRCGTSA
                     ELLRTSALYRDLAGLWEPDQPLRDDGGSNGSPGDDGGSNDPLRDDGGPNGSPGDDGGSN
                     DPLRDDGASNGVLGNDDGSNGFLRDDGRSKGPAGPVLENGRSNGSSNAASRGGGVKSTP
                     PPSPV"
     gene            complement(17069..17680)
                     /locus_tag="B083_RS0107270"
     CDS             complement(17069..17680)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="B083_RS0107270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_018489195.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLGAGQGIEVTTADREAIRPALAGSG
                     PVPDVILTDLDCPDSLDLLKEVRSLAEPHGRGCPLAVLTRSDRPRGLRRAYEAGARGYI
                     DKYRPVDDLAEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSLAEGGETVTGI
                     AGRLHLTQGTVRNYLAAAIRKSGARNRVDAIRRAKEAGWI"
     misc_feature    complement(17252..17254)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17273..17275)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17727..17741)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.65"
                     /tool="antismash"
     misc_feature    complement(17728..17740)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    complement(17778..17791)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            complement(17961..18842)
                     /locus_tag="B083_RS0107275"
     CDS             complement(17961..18842)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="B083_RS0107275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_028416226.1"
                     /transl_table=11
                     /translation="MSAQDSVTADRRRQFAEEARSERPDLALLCLLLGAEAGPVGPEEP
                     RPVRPGDASPDPYGIDAAQIELDRLAGLLPHGIRTPVGWAGALAGLLGERHEFGGSPAD
                     YQRLESSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVYGVALPGHFVVGFGDPEHPVL
                     VDPFTGGAPLTGEEAGLFVAGATGARLEPSMLAPARPLEIVLRILNNIRAWAAARPERT
                     DVSLWAVDLSLLLPSHPARLRYERAQLLVQRGEFQRGAAEMEEYAEVLDTIEPTTAETV
                     RHKAQAARALLN"
     gene            complement(19009..20040)
                     /locus_tag="B083_RS0107280"
     CDS             complement(19009..20040)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061638.1"
                     /locus_tag="B083_RS0107280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_028416227.1"
                     /transl_table=11
                     /translation="MEFTMGGRLEVRITPADVGKRVSVRRRSAGGGSGAEFTDTVGVLT
                     SWNDGVVAITRKSGESVRILESTLVAGKVVPAAPARRRGPAASFAELAAVTARAWQPVE
                     SEPLGEWRLRAAGGFTRRANSVLPLGDPGLPLGEAFERIEQWYGERGLPPYVQTATGAE
                     GAQETLCAELERQGWRREVTAEVRIAALAPVGDLDADVSAVRLAREPDAAWLSRYQRFS
                     TPGPHVLRVLGSGPSVWFATVAGGARGEGAGAGSGDGEPPAAIGRCVVDGRWAGFMAVE
                     VAPGHRRRGLATAVMAALACRALDEGASAAWLQVEEDNEGARALYDGMGFAPHHRYHHF
                     RPA"
     gene            20158..20478
                     /gene="fdxA"
                     /locus_tag="B083_RS0107285"
     CDS             20158..20478
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="B083_RS0107285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin"
                     /protein_id="WP_018489192.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHSFIAGLPPQ
                     NQ"
     gene            20664..21758
                     /gene="dapC"
                     /locus_tag="B083_RS0107290"
     CDS             20664..21758
                     /EC_number="2.6.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value:
                     5.3e-46. Score: 149.3. Matches aSDomain:
                     nrpspksdomains_B083_RS0107290_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="dapC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984558.1"
                     /locus_tag="B083_RS0107290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="succinyldiaminopimelate transaminase"
                     /protein_id="WP_028416228.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.4e-45, bitscore:
                     149.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPAFPWDRLTPYKTTAQAHPDGIVDLSVGTPVDPVPEV
                     IRRALVAAADSPGYPTVWGTEALRDALTGWVERRLGATGVTHANVLPVVGSKELVAWLP
                     TQLGLGPGDKVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPAGLKLLWLNSPSNPTG
                     KVLAKHELVRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGGHYEGIVAVHSL
                     SKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTPAPVQAATVAALGDDTHVAEQRAR
                     YADRRLALRAALEAHGFRIEHSEASLYLWATRDEPCWETVAYLAQLGILVAPGDFYGPA
                     GESFVRVAFTATDERVAAAVKRLS"
     aSDomain        20751..21752
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0107290_Aminotran_1_2.1"
                     /evalue="5.30E-46"
                     /label="B083_RS0107290_Aminotran_1_2.1"
                     /locus_tag="B083_RS0107290"
                     /protein_end="363"
                     /protein_start="29"
                     /score="149.3"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPEVIRRALVAAADSPGYPTVWGTEALRDALTG
                     WVERRLGATGVTHANVLPVVGSKELVAWLPTQLGLGPGDKVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPAGLKLLWLNSPSNPTGKVLAKHELVRIVAWAREHGVLVFSDECYL
                     ELGWDAEPVSVLHPDVCGGHYEGIVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRK
                     HGGMMTPAPVQAATVAALGDDTHVAEQRARYADRRLALRAALEAHGFRIEHSEASLYLW
                     ATRDEPCWETVAYLAQLGILVAPGDFYGPAGESFVRVAFTATDERVAAAVKRL"
     gene            complement(21937..22392)
                     /locus_tag="B083_RS0107295"
     CDS             complement(21937..22392)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127370.1"
                     /locus_tag="B083_RS0107295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028416229.1"
                     /transl_table=11
                     /translation="MSLPLTRRIARTALLIAAGAAPVVGAAGAASAAELPQTPDLGGLT
                     ALDGAGLGNTVDSAARQGTQAAGETGGRLVGTALPAAGATVGKTARVAAPAVQETAGQT
                     AGSAGEALGGVADAAAGGLPTDSLTQGGLPTDALTKGGLPLDGLPIG"
ORIGIN
        1 gatgtccgac tccccgatgt ccagcaccgc ctggatgtgc aactgggccc cggtcagcgg
       61 ccggtcaccg accgccagca cccgcgcccc accctcgtcc gcgatccgta cgagccgccc
      121 gtccggcgcc cacgcgggca ccccgccgaa cagatccagc cagaccgggt cctcgtccac
      181 atggacgatc cgcgtctcac cggactccgg gtccaccgcc agataccgct gactgcgctg
      241 gtcgcgggcc tgcaccagga ggagcggggc gcccgcggcg gaccagtgca cctgggccag
      301 gtacgggaac gccgcccggt cccagaccac ctccgtacgg gccccctcca ggtccatcac
      361 gaagagccgc acctcggcgt tgggcgtccc cgccgccgga taggccacct cggccggctg
      421 ccgctccggg tgcgcgggat ccgcgatgaa ccaccgctgt acggcgctgt cgtcggcccg
      481 cgcgaccagc agccggtccg actccggcga ccaccagaag ccccggaagc ggtgcatctc
      541 ctcggccgcc acgaactcgg ccagaccgta ggtgacatgg gcctcctcgg gctcggccag
      601 cgccctgtcg ccctcgcccc ccgcgcccac gacccgcagc gcgcccttgg agacgtacgc
      661 gatccggcgg ccgtcggggg aggggcgcgg gtccagcacc ggtcccggca ccggcagcgc
      721 ccgcgcggtc ccggcccgca actcggccac gtacaccttc ccggagagcg cgaaggcggc
      781 caactcggcc gccgcgtcca ccgcgtagga gacgatcccg gccgacccct cccgggtccg
      841 ctcgcgccgg gcccgctcct gggccgacag ccgctccgcc gaaccgccca gcagcgcctc
      901 gggatccgcg accagccgct cctgcccgga ggccgggtcc agcacccaga ggcggttggt
      961 gcggtcggtg cccgaggtgg agcgcaggaa gatcacccgc gtctcatccg gtgagacggt
     1021 gaaggctctc ggtgcgccga gagtgaaccg ctgggtccgt gcgtgctgac ggggaaagga
     1081 cggcttcggt gaggtcatgg cctcgaacct agctccgcgc agcggttcgt gcgcccctcg
     1141 tgctgctgtg ccccgatcaa tgcgttggca cggatagtta tgatccgtag cgctcggtgg
     1201 gtaagaaccc gtcgacccgt gtatccccgt cccgaccgta ctgatggagg tgaaccgccg
     1261 tggcgctctc gatttcggcg gtggtgctgc tggcgatcat cgtcttcctg ctgatccgga
     1321 aatccggact gaagggcgga cacgcggtga tctgcatgct gctggggttc tacatcgcca
     1381 gttcgtccgt tgcgccgacc atctcggacc tgacgtcgaa cgtggcgggg atgatcggga
     1441 gtatcaagtt ctgaccgtcc gcatccgtcc gtatccgcct tccgaccgcg tgtacccgca
     1501 ttccgcccgg gtacgcccgc gctgacgccg tcggcgggga gcggggagca ccggggcccg
     1561 ccgggctcgt agggtggtcc ccatgaagga cctccccgcc cgccgtctgc tgctggtgca
     1621 cgcgcatccg gacgacgagt cgatcaacaa cggcgccacc atggccaggt acgcggccga
     1681 gggcgcccac gtcacgctgg tgacgtgcac gctgggcgag gagggcgagg tcatcccgcc
     1741 cgccctcgcc catctcgccg ccgaccgcga cgacaccctc ggtccgtacc gggtgggtga
     1801 gctggccgcg gcgatgaagg aactgggcgt caccgaccac cgcttcctcg gcgggccggg
     1861 ccggttccgg gactccggga tgatgggcac cgagcagaac gagcgccccg gcgccttctg
     1921 ggccaccccc gtggacgagg ccgccgcccc gctcgtggag atcatccggg aggtgcgccc
     1981 ccaggtcctg gtcacctacg accccgacgg cggctacggc caccccgacc acatccaggc
     2041 ccaccgggtc gccatgcgcg ccaccgggct ggccgccgac ccggcgtacg gcaccggcgc
     2101 cccgcacacc gtcgccaagg tctactggaa ccgtgcggag cggccggtgg tggaggctgc
     2161 cttcgcgcac ctccgcgcga cggcccccga cgccttcccg ggcatcgcgg cggtcgacga
     2221 cgtccccggg gtggtcgacg gcgacgggat cacggccgag atcgacggat cggcgtacgc
     2281 cggggcgaag gcggcggcga tgcgcgccca tgcgacccag atcgcgctgg ccgacgaggg
     2341 ccccttcttc gccctctcca acgacctggg ccagccgctc ctgacgaccg agtactacca
     2401 actggtccgg ggcgtcccgg cggccgggac cggggcgcgc gaggacgacc tgttcgcggg
     2461 ggtgacggag gcggagaccg cgagcgcgcc ggagcccggg acgggtgccg atgccgtacg
     2521 gggtgtggcg ccgggtccgg ggacggaggc cggggccgat gccgtacggg gcccggtgtc
     2581 gggttccgct tcgggtgtcg ggccggattc cgtatcgggt ccggcctccg gatcgggggc
     2641 gggcgcatga gcgggcggaa cggcaagggc gggcggagcg gcgggggacc gggccgcgac
     2701 cgtgatcgcg cccgtgcggc gggcggcgac gcaccggcct ccggcgcgac ccgctccgaa
     2761 gctgcgcgct ccggagcgtc ggacagcggc aacgccccgc gctccggagt gcccggcagc
     2821 ggcgaggcgg cctcgcgcac cggcactccg cgtacgggca cgccgcccca ggtccccgcg
     2881 ggcgtcggct tcaccggccg cccgaacccg gcccggatcg ctgcctactt cgggctcgcg
     2941 gtgctcggcg cactcgtggc gctggccggg acgctgctcc aagccgcctg gttcccgggc
     3001 gggttgatca tcgccctggc gggttcggcg ggcctcttct acggcggccg catcctgacc
     3061 ggcacccaga tcggcgcgct cgcgcccgcc gtcggctggt tcgtcacggt gttcctgctg
     3121 ctgtcgggcc ggccggaagg cgactacgtc ttcggcgacg aactcggcct ggcgctcttc
     3181 atgctcggcg gaacggccgt ggctgtgatg tgtgccacga cctccaaggt gccgcaatca
     3241 gccactcctc gtggccggtc cggtatctga agtgctaagt ccgcgcccgg aatgcccccc
     3301 acaggtgtga tgccgacgtg gaggtttccc ccggtcgcgg agtgtcctgc ggcggcggcc
     3361 agtatggtgg tgcgcgcgcc gagccgtccc ctggcctgcg gcatggggga agtacgggcg
     3421 gcggagccaa tcgggagaac ctgctttgag tcgtgaaact gacagttcgt cctccgggcc
     3481 ccaggggcgc ggtggagccg cgtacccgtc gggtacgccg ccgtacggat cccgccagta
     3541 ttcgtcggcg gccggctcgg acgagtcccc ggaatccgtc gatccgcccc ggcccgaaga
     3601 gccgaagacc gagacgacgc tgacgacgcg catccggatc aacatccccg ggtcgcgccc
     3661 catcccgccg gtcgtgatgc ggacgccgat ggccgagagc gacctcgcca ccggccgccc
     3721 cgacgcggag cgcacgggct cgaccccgcg ccccggcaca ccgccggccg cgccgtcggg
     3781 tctgacgggc ggtgccgcgg cggcctcgtc cgcggcccag gcacgggacg cccgtggcgc
     3841 cggggacggc ggcggttccg ccgatccctc cgcctcgtcg gcctccggcc ccgccgctgc
     3901 ggaggaaggg gccaaggcga agaccgggag cgactggttc gccccgcgca agagcccggc
     3961 cccggcgccc gcaccggcct ccggttcggc gggcatgccc ggttccggtt ccaccggcgc
     4021 gggcccgctc ggctccggcg gcccgggcgc gtccggcccc gacggtggca cccggccgcg
     4081 tcccgacctg ccgtacttct ccgacgccga cccgcgcccc ggcggcggac ccggcgcgcc
     4141 cggttccggc atcccaggcc cggacacacc cggctcgggc atcccgggcc tgggcgtccc
     4201 cgccagcgcc ctggacggct acagcgccga ggcccccggc ggcggtcccc gctccacgac
     4261 cgaccccggt gtccacgcgc acggcccggg ccggcccggt gggcccggac cggccggccc
     4321 cacgacgggc ccggtcaccg gcacctcgtc cctcacgccc gacctggacg gcatcccggg
     4381 actcggcggc cccggcccga tggtcccggg cgcccccggc ggcgtaccgc cccggctctc
     4441 cgacgacacc gcgatcctga cgccgcagtc cccggcgccc gacacgggcc ccggcggcca
     4501 tgtctcgggc gacacgctga cgagcggcat ccccgtggtg cccagcgagc cgcgctcgac
     4561 gttcccgggc gggccggacg gccccggcgg cgcgttcccg ggcgggccgg gctcgggcgg
     4621 cggccccttc cccgggggtc cgggcggctc cggcagcccc ttcccgggcg gcaacgaccc
     4681 gttcgcggac ggtcccgacg gcccgggcgc ggccaagacg ccccgccccg ccgccgcgcg
     4741 cccggcgccg acgcccgcac cccccgccag gaagggccgc tccaagctgg tcctcctcgg
     4801 ggtggccgcg gtcgtgctgc tcggtatcgc ctacggtgcc ggactcctcc tgaaccactc
     4861 cgaggtcccc aagggcacca cggtgctcgg ggtcgacatc ggcggcggca cgaaggagga
     4921 ggcggtcgtc aagctggacg ccgctctcgg cgagcgctcc cgggccccgc tgtcgctctc
     4981 cgtggacggc aaggaggaga agctggaccc ggagaaggcc ggtctcaccc tggacagcca
     5041 ggagaccgtg cgcggagccg cgggcagcga ctacaacccg gtctcggtga tcggctcgct
     5101 cttcggcggg gcgcgcaccg cggaccccgt gatcccggtc gacgaggaga agctcggcgt
     5161 cgccctgaac gacctggcgg gcaccgccgg ttcgtcccag gacggcacga tccggttcga
     5221 gccgaacaag gcgatcgcgg tcccgggcaa gcccggcaag accctggacg tcggccagtc
     5281 gctgatctcc gtccgcgacg cctaccgcgc gcaggtccag accggccgcc ccaaggtggt
     5341 cgaactcccc gtcgccaccc gggaacccac catcacccag gccgaactga cccgggcgat
     5401 gaaggagttc gcggagcccg cgatgtccga cctgatcacc atcaaggcgg gcccgaagca
     5461 gatccagttc ggcccggcga ggtcgctgcc gcagatcctc tccatgaagg ccgtcgacgg
     5521 ccgcctggtc gacgtctacg acaagaaggc gatcaccacc ctgctggacg gcgtcttcga
     5581 cggcatcacc gccgtcaagg ccgacggcaa gcagcacccg gtcggcgcgg acgacgtggc
     5641 ccaggcgatg aagaccgccc tcaccggcaa gaccccggcg gagcgcacgg tcaccatcga
     5701 cctcaccggc gagggctgac ccccgcccgt aggagcccac cagacggccc ccgcccggac
     5761 ccccggggcg ggggccgtcc ccgttccttc cgccccgaca ggccgaccgg tccccgcccg
     5821 tcgtgtcggg gaaggggggc ggagcgggcg tacgcgaggg cccggacgga acgcggtgga
     5881 gcggggaccg gcgcccctcg gcaagccggt ccccgctccc gtacgactcc cctcggcggt
     5941 cggcgctagg ggaagttcac cacctgggac gggacggtct ccgtgcccga ggtcggggcg
     6001 ccgatgtcgt tgatcacgtg ctcgaactgg ccgttgccgc ccagggacac cacgatcagg
     6061 tggtggaact tcaccccggg cttcaccggg gccttgaatc cgtgctcctg gacgatggtc
     6121 gggtcgacgt tgtagtagca gtagctgccg agcccccagc cctcgtgctg ctcgacggag
     6181 tcgtcgaccc ggtaggcggc gtaccccttg gtgtcgccgt tctggatcgc ctcctggttc
     6241 ggggcgtcgt aggccttctc gttctggaag aagatggtgc ggccgcgttc gccgtaccac
     6301 tcgacgtcgt acttgttgaa gtgctcgacg aagagtccgg tggccaggac gtcgtcgccg
     6361 ttgacgcgga cgccgtagtc ggcgcggttg gtctcccagc cccagccctc gccgtggtcc
     6421 gcccgccaca cccaggtgtg gtcgatgatc acgtcgtcgc tgttgacgac gatgctggtg
     6481 gtcgccttgc cggggcccgc gccgccgatc cgtacgaaca cgtcctggag cgaggtcggg
     6541 ttggccgcgt ggtcggcgga ggcgccctgc gggccgacct cgatcagcgt ctccgagttc
     6601 accggacccg cgtcgaccag cagccccgcg agcttcacac cgtccacgtc accgaccttg
     6661 atcgcggtca ccccgttgtc cgggatgatc gtcgcgaggc cgatgccgag ggccaccgtg
     6721 tccgggcggt cgatggtgat cgtctcgtcc acgtggtaga cgccgggcgt gaagagcagg
     6781 tgcaggccct gctccaccgc cgcgttgatg gtggccgcgt ccgccccctc cttcacgacg
     6841 tagaactgat ccagcgggat cgactcgccg ggcggggtgc cgtcggccca ggagacaccg
     6901 cgtgcgttct cgcgcttctg cgggacgaag accttgtagt cgtcaccgtc gaggtagagg
     6961 aacggcttct cccgggagat cggcgtcgtg tcgagcgtgg tgtacggcgg ctcggggaag
     7021 ctgttggccg gggcgccctc gacgcccgag aaggtcatgt tccagacgcc gttggtccag
     7081 ccgccgacgg agctgtcgcg ggtgtaccac tgctgctgcg agtacgggcc cacctcgccg
     7141 tcgatcttgc tgtccgcgat gtagccgccg ctggcccagc cgtagccgtc gggcgccagg
     7201 ttcagcccgc ccttgacgtg catccggcgg aagggcgcgg cctgggagac cgcccaccgg
     7261 ttggtgccgt tcaccgggtt gagggtgagg ttttcggccg aacgccagaa gttctgggtg
     7321 gcgttgccgt cgaaccagcc cgcgtcgacc gtgacatcgc cgttgaacgt ggtgtcgttc
     7381 gggtgcagtc cgagcccggc gatcgaggtg tagaagccga tctgcgcgtt gatgtcgtcg
     7441 tacgtgcccg gcttgaacag cagcgcgtgg cggtccaggc cgaactgcgc cgactcctgc
     7501 ttcctgaaga tctcgtcgac cttgccctgg atgccgggcg tcgacgggtc gaagacatgg
     7561 acgttcgggc cgaggtcacc gccgcccggc acggcctgga tctcctggcc gtccctggcc
     7621 tcctcgccga acgccgtctg ggcggtgggg acggccatga ggagcgacac ggcgagcgcg
     7681 gcgaagccga gggccctgga ccggcggcgc ccgcggggag cggcgccgga gtggggtgct
     7741 gtggggggaa caggcatgaa ggtacgtctc ctgggtcgtg gttgcgtgtg cacgacggac
     7801 gggcgggaga gcgcccgtgg ggagagatga gagagcgctc tctcgttacg gtgatgtttc
     7861 cccgataggc ctgtacgcgt caagagttgt gcgccgggtt catgggccgc cggggtgttc
     7921 gtcgacttcg tgaagcgacg gcccgtccgc gggcggtgat cgtcgcggcc cgccccgggc
     7981 ccggacgcgc gggggtgcgg cgtacggggg accatggggc catgagttcg cttgacgccg
     8041 gtgcgccgcg cccggcccgt gacgacccgc cgcccccggg cgtcggccga cggatcaagg
     8101 tctggttccg cttcgtcccg cgtgaggact ggctgccgta cgacaccgag gggttgtggg
     8161 cgacccggct gagcgccgac accgcccgcg tcgacaacgt gccgttcctc caggacgggg
     8221 tggccgaggg cgagaccgta cggttcacga ccgacgcgga cggggtgcac tgggccaccg
     8281 ggcgggtggc cgactccggc aactgcaccg tccgcgtgct gcccgtgccg gacggccccc
     8341 tcgggcggga cgcccgcgcc gtgcacgagc ggttctcccc gttcgggctg ggcggcgagg
     8401 tgttcagcgc ggactttccg ctggtggcgc tcacggtgcc gggcggtgcg gacttccggg
     8461 cgatcaaggc gctgctcgtc cgggggcagg acgaggggtg gtggcacttc gaggtcgggt
     8521 gcgccacgga ggcctggcgg agggcgtagg ggtacggggg cggcttcagg gggacgtgag
     8581 cggcggggcg ggccgggtgg cgtgggggta ggcggcgcgg cgggtccggt gcgtgggtcg
     8641 ggggcacggg gtgcgccgac gccgggaccg ccgccgaggg gcggtggtgc gcggggcggc
     8701 cgggcgccgg ccccggggcg cgccggcgcc gggcccgggc cgggaccggc cccgccggtc
     8761 ccggcccggc ggggccgcgc ccggaaggtc aggccgtagg ggccggagcc ttcccgtccc
     8821 cctcctcccc gatcttccgg atcacccggg ccgggttgcc caccgccacc acgttcgccg
     8881 gcaggtcctt cgtgaccacc gcccccgcgc cgaccaccgt gttctccccg atgctcaccc
     8941 ccgggcagac gatcaccccg ccgcccagcc acacgttgtc cccgatcgtg atcggttccg
     9001 ccgcctccca cttggcccgg cgcggctccg ggtcgatcgg gtgggtcggg gtgaggagct
     9061 ggacgttcgg gccgatctgg acgtcggcgc cgatcgtgat gcgggcgacg tccaggaaca
     9121 ccgccccgaa gttcacgaac gtacgcgggc cgaccgtgat ctggtggccg tagtccaccc
     9181 gcagcggcgg gcggatctcg gcgccctcgc ccaactcgcc cagcagctcg gccagcgccg
     9241 cgcggcgtgc ctcggggtcg gcggccgagg tggcgttgaa gcgctcggtc agaagcgcgg
     9301 agcgcagcgc gtccgccgcg atctccgggt cgtcggcgag gtagagctcg cccgcgagca
     9361 tggcctcccg ctggctgcgc ggcgcgctcc gcgcggcgcc ctcggccccg gggctcccgg
     9421 tcgcggcgtg ctcggcggag tcgggggtgt tctggctggt cacgaggtcg tcgtctcctt
     9481 cgtctcctgc gcatcccgcg tacgggatga tccgtccccg tgcagtctgc ccgccgggtc
     9541 cgtcccctgt cccgggggat tcggccccga gggattcggc cccgagggat tcggctcgga
     9601 gggatccggc cccgagcgtt cccgtcccga gcgttcccgt cccgagcgtt cccgtcccga
     9661 agtccgttgt tccgaaagtc cgttgttccg agggtcctcc cgcccgcagc cccggtgccg
     9721 gggtcaatgt cggggtccgc cggacgcggg gctggtgcgc cgccgccggg acggacggtc
     9781 cgtgctctgt ttccggacgg cggcggggga cgggctggtg cgcgcggcgg gctgaatgcg
     9841 cccggcgcgc gccccgggcc gtagctggga agtcaccggt gggcgatgcg ctccgcatgg
     9901 atcgcgcgca tgtatgagtc gtgacatcgg tgactattgg tgacgctcat cgttatgaca
     9961 atttctctct cgccacgcaa cgccgagcga agggaatgtc gtgaatccgg agtacgccgc
    10021 gtactgccag gcggaccgcc gcttctacga cgcaccccac cgttccctcg aagcgggcgc
    10081 cgaggagcgg acgttctacg ctcccgtccg cggcggagcc cccgaggggt ggacccgctc
    10141 ccggcgcggt gactggctct ccttcagccc ggacgggctg cggctgccgg cccaggggtg
    10201 gaagctccac ataacggccg ccgccgacaa cgcggaatcg gtgctggagc gggtcgcggc
    10261 ccactgtctg gcccgccggc tgcccttcaa gtgcataccg tcccccgccc tgctggccct
    10321 gcggaactcc aagtacgcgg accgggcggg cagcggcaag ttcatcaccg tgtacccgca
    10381 ctccgaggag acgttccccg aggtgtgcgc cgcgctgatg gagctgctgg agggcgagca
    10441 cggcccgtac atcctgagcg acctgcggtg cggcgacggg cccgtgcaca cgcggtacgg
    10501 ggcgttcgcc gcccgcttct gcacgggccc cgacgggcgg cccgtccccg ccgtggccga
    10561 tccgcaaggg cggctggtcc ccgacgaccg gggcccggcc ttccgggtgc ccgcctgggt
    10621 gaccccgccc gacttcctgc gcccgcacct ggaggcccgc gccgccgtcg gcctcggcga
    10681 tcttccgtac accgtcgaga aggcgctgca cttctccaac ggcggcgggg tctacttcgg
    10741 ccgcgacagc cgcaccggcg agcaggtcgt cctcaaggag gcccgcccgt acgccgggct
    10801 cgccgccgac ggggccgacg ccgtcgcccg gctggagcgg gagcgcaccg cgctggagcg
    10861 gctggagggg ctggagtgcg taccggccgt gcgcgacgcg ttcgaggtcg gcggccacca
    10921 cttcctcgtc ctccagtatc tgccgggcac caccctcaac accgtcttcg cccgccgctt
    10981 cccgctcgcc cggcagaacc cggcccccga gctgctcgcc ggtcatgtgg cgtgggcgga
    11041 ggaggtgtac gggaaggtcg agcgcgccgt cgaggccgtc cacgcccggg gcatcgtcat
    11101 cagcgatctg cacatgagca acgtcatggt cgacgaggag tccgggcgga tcgccctgct
    11161 cgacttcgag gccgcctccc cggccgccga ccgccgccgc cagatcgtcg ccaacccggc
    11221 cttcgtggcc ccgcccgacc ggcgcggcac cgacatcgac cggtacgcgc tcgcctgcct
    11281 ccggctcgcg ctctatctgc cgctcaccac gctcttcggc atcgaccgca tgaaggcggc
    11341 gggcctcgcc cgggagatcg cccgcgtctt cccggtgggg gaggagcggc tgcggccggc
    11401 ggtcgaggag atccagcgcg gggcggaggc agccgggacg gacacgggcg cctcctcccg
    11461 taggaacccc gcctcccctg ccgatctcgc ctcccgtacg gacgcgagta ccggtacggg
    11521 cgcaggcgca ggcgcaggta cggcgccggg ggccgacgcc tcccggacgc tcccgcccga
    11581 ccccggcgac tggccggaga gccgtgccgc gatggcccgg gccatcgccg cctcctgtac
    11641 gcccgaccgc gacgaccgat gtttcccggg cgacatcgcc cagttcgcca ccgcgaccgg
    11701 cggccagtcc ttcgcgtacg gcgccgcggg cgtgctctac gccctgcacg agaccggcgc
    11761 cccgcgctgc gagccggccg aggagtggct ggtgcggcag gccaaggacc cggcctccgg
    11821 ctccccgctc ggcttctacg acgggctcac cggcatcgcc tggacgctga accggatcgg
    11881 ccgcaccgcc gaggccgccg acctcgtccg gatcgtcctg gaccagccgc tggagggcct
    11941 ggcacccgga ctgcacagcg ggtacgccgg tatcggcctc gccctcgacg acctggcccg
    12001 caccgccccc gccaccgagg ccccggcgct cgccgcggcc gccgggcgct gcaccgccct
    12061 cgccgtacgc gccctggtgg acggcccgcc gtccccgcgc accggcctcc tgcacggcgc
    12121 gaccggagtc gccctgctgc tgatccgccg gtacgccacc accggggacc ccgccctgct
    12181 cgacgtggcc gccgccgccc tccggcgcga cctcgaccgg tgccgggccg gcgacgacgg
    12241 cgaactcctc gtcgtcgagg gcaagcggct gatgccctac ctcggagcgg gcagcgccgg
    12301 gatcgcggcc gtcatcgacg cctacctcgc ccaccgcccc ggcgacgcgg agctggaggc
    12361 ggcgggccgg gccctgctcc cggccgcgct ctccgccttc tacgtccagc ccggactgct
    12421 gcgcggctcg gccggactcc tcatgcacct ggcggccaca cccctgtgcg acgcggagac
    12481 ccgggagcgg gccatccgcc tccacacccg cctgctcgcc ggtcacgccc tcacctacgg
    12541 aggcggactc gccttccccg gtgagcagtt gatgcggctg tcgatggacc tggccaccgg
    12601 gaccgccggc tgcctgctcg ccctgggcgc cgccctcggg accgccccgg gcgccccacc
    12661 gggcccggcc accacgcttc ccttcctcgc cgccaccgtt ccaccggtgg cgcgccccgg
    12721 ccgcgcgagc ggccccaccg accggctcct tcaggggtcg tagcaccacc accgctcaac
    12781 acacagccgg agcaacgggt tccggttacc gtcccagaaa ggaaacacca tcatggcgct
    12841 tctggacctt caggcgatgg agaccccggc cgaggagtcc ttcggtgagc tcgccacggg
    12901 cagccaggtc tcgctgctgg tctgcgagta cagctcgctg agcgtggtcc tctgcacccc
    12961 gtgacgcctc gccgcccggg ccgccggtga tcccaccggc ggcccgggcg gcccgtccgc
    13021 cggtcccgag cggttcgtcc gcccgggacc ggcggcgtac gtctgtccgc gcgcgcccac
    13081 cgatcgacac gggtccggaa agggagacca cgtgcggccg aaaccccgcc cccgcctccg
    13141 tcctccggcg ccctccggcg cacgccggct cgcccggcgc cacccgggcg ccctcctcgc
    13201 gctcttcctc tgctccaccg gcggggcgct cgccgccctc gccctccccg ccgccctcgg
    13261 acacaccgtc gaccggctcg tcgacggcgg agccgtgccc tgggcggggc tgctgctctg
    13321 cgccgtactg accctcgccg agaccgggtt cgacgcgggc gccgccgtgc tcaccaccag
    13381 caccggagcc cggctcaccg cccacctccg cacccgcacc acggcccggg tcctggccgc
    13441 cgaaccccgc cgcgccctcg ccgtgccgac cggggacctc accgcccggc tcaccgcccg
    13501 caccgccgac gcggcgaccg cgcccgtcac cgccgccggg gccgtcgcgg gcgtcctgct
    13561 cccgctcggc gcgatcgtcg gcctcttcgt catcgacccc tggacggccg ccgccttcct
    13621 gctcggcgcg cccctcctcg tcgccctcct gcacaccttc acccgccgca ccgccgacgc
    13681 cggggccgac taccagcgcg cccagtccgt catcgcccac cgcctcaccg aggccctcga
    13741 cggcgccgac accatccgcg ccgcccgcac cggagcccgc gagtaccgcc gcatcctcga
    13801 accgctcacc accctggcgg cccacggccg acgcacctgg accgtgtacg ggcgggccgc
    13861 cgggcagagc gccctgctgc tgcccctcct catgctgctg gtcctcgcgg tcggcggcct
    13921 ccggctccag gcgggcgcga tcggcgtcgg ggacctcgtc gccgcctccc ggtacgcggc
    13981 cctcgccgtc ggcatcggct ccctcaccgg agcgctcggc gccctcgccc gcagccgcgc
    14041 cgccgcccgc accctggacc cgctgctcac cctggacccg ctgccgcacg aggggctggg
    14101 cccgccccac ggcggcccgg gccacctcga actccgggac gtcggggtcg tacaggacgg
    14161 aaagcggcaa gacgtacagg gcggaaagca gggcggaaag caggaagacg aacagggcgg
    14221 ggaagcactg cccgacggcg aacccgaccg aaagccgctg ctcaccggcg tgcacctcac
    14281 cgtccccggc ggaacgtccc tcgccgtcgt cggccgctcg ggctccggca agtcggtctt
    14341 cgcggcggtc gtcggacggc tgctcgaccc ggacaccggg accgtgctcc tcgacggaat
    14401 ccccctgacc gccatggaac ccgcccgtct gcgccccgag atcgcctacg ccttcgcccg
    14461 cccggccctg cccggcacca cggtcgagga cacgatcgcc ttcgggccgt ggaccgccgg
    14521 gcccgccgcg gtacgggagg gggcgcgcgc cgcccgcgcg gacgggttcg tcggactcct
    14581 cccgtacggc tacgccaccc cgctcaccga cgccccgctc tccggcggcg aacgccaacg
    14641 gctgggcctg gcacgcgcgt tcgcccatcc cggacggctg ctgatcctgg acgacgccct
    14701 ctccggcctc gacaccgtca ccgagcacca cgtccgccgc gccctcgacg agcgggccgg
    14761 gcgctgcacc cgggtgatcg tggcccaccg cctctcctcg gccgcccgcg ccgaccaggt
    14821 cctctggctg gaggacggcc gggtccgggc gacgggcccg cacgaggagc tgtgggccga
    14881 tccggagtac cgggcggtct tccgtacgga gacgggtgag gcggaggaga tggcggaggc
    14941 ggacgaaggg ccaggagcgg aaggggcgct tccacgggcc cgtacggaag tggaggcccg
    15001 gtgaaagcac cccgaacggc ccgtcccccc ggccccctca cccgggtcac ccgcgacgcc
    15061 cgccccttcc tccgcgcccg caccggaacc gtcctgcggc tgggcggctg gtccctgctg
    15121 gagttcgtcc agaccttcct gggcggctac ggcgtcgccc gggcgctgga ccacggcttc
    15181 ctcgccgggc gcccgctcac cggtctgctc tggctggccg tcgccgccgt ggccgtcctc
    15241 cccgcccagc tcgccacccg cggggtcttc ggacggctcg cggacctggt ggaaccgctg
    15301 cgcgacgggc tcgtgcggcg cgcggtctcc cgcgcgctcg tcggtgccct cgaacacccc
    15361 accggcacca ccgcccgctc cctctcccag gtcacccacc agagcgagat cgcccgggac
    15421 ggctgggccg gactcgtcct gacgctccgg tcgttcgtgt tcacggtggc cggggcggtg
    15481 gcggggctgc tggccctgga gccgcggctc ctcctcctcg tgctgccccc gctcgtcctg
    15541 ggcgccggtc tcttcctggc cactctggtg ccgatggccg cccgccagcg cgactacctc
    15601 accgccgacg aggcgtacgc cgcccacgcg ggccggaccg ccgccgacct gcgggacatc
    15661 gccgccgccg gggccgccgc ccgcaccgtg acggagtccg gggaactggc cgacgcacag
    15721 gtccgcgcgg cccgttcact ggcccggtgg tccggcgtac gggtggtggc cctggcggtc
    15781 tgcgggcgct tcccgcccct gctcctgctg ctcggcgccc cgtggctgct ccgcgacggc
    15841 ctcacgccgg gcgcgctcgt cggcgcgctc acctacctca cccaggccct ggccccggcg
    15901 gtccaggcgc tgatgacgat gctctccacg gtcggcggcc ggctgctggt ggtcctggac
    15961 cggttcacgg acgcgccgcc gccccctgcc gaggacggag acgacggtcg ggcgcacggt
    16021 cacggacagg ggcacagccg ggggctcgac ggtcacgacc ggggcgcgcc cacgccgcgc
    16081 cacgcccccg tcgccgaact ggacaccgtc accttcgcct acggtcccgc cgcgcgcccc
    16141 gtcctggacc ggctctcgct caccgtcgcc cccggcgagc acctggccgt cgtcgggccg
    16201 agcggcagcg gcaagtcgac gctcgccgcc gtcctcgcgg gggtggagac gcccggtgcg
    16261 ggctccgtgc gatggctcgg gcggccggtg cgggcggccg acgccacctc cgtacgggtt
    16321 ctgctgcccc agcacgcgta cgtgttcacc ggttcactgc gggacaacct ccggtacctg
    16381 tgccccgacg cgaccgaccg ggaactggcc gccaccgtcg acgcgctcgg cctggacccg
    16441 ctgctcaccc ggctcggctc cctggacgcc ctcgtcgaac cggaccggct ctcccagggg
    16501 gaacgccagc tcgtcgccct cggccgggcc catctggcgg ccccgccgct catcgtgctg
    16561 gacgaggcca ccagccggct cgacccggcg gccgagaccc gcgccgaaga ggccttcgcc
    16621 gcgctgccca gcgccctggt ggtcgtcgcc caccgcctca gctccgccca ccgcgccgac
    16681 cggatcctgg tgatggacgg cccccgcacc cgctgcggca cctcggcgga gctgctgcgc
    16741 acctcggcgc tctaccggga cctggccggc ctctgggaac cggaccagcc gctccgtgac
    16801 gacggcgggt cgaacgggtc gcccggtgac gacggcgggt cgaacgatcc gctccgtgac
    16861 gacggcgggc cgaacgggtc gcccggtgac gacggcgggt cgaacgatcc gctccgcgac
    16921 gacggcgcgt cgaacggggt gctcggtaac gacgacgggt cgaacgggtt tctgcgtgac
    16981 gacggccggt cgaaggggcc ggccgggccg gtccttgaga acggccgctc gaacgggtcg
    17041 tcgaacgccg cgtcccgtgg cggcggggtc aaatccaccc cgcctccttc gcccgtctga
    17101 tcgcgtccac ccgattgcgc gcgccggact tccgaatggc ggcggcgagg taattgcgga
    17161 ccgtcccctg ggtgagatgc agccgccccg cgatacccgt gacggtttcc ccgccctcgg
    17221 ccagggagag cacgctcaat tcccgggggg ataagggcat gtcggccact tgtaacaggc
    17281 tgaaggcaag tgactcgtcg atatgccgcc cgccgtcggc cagtttgtgc atgacctcgg
    17341 cgagatcgtc caccggccgg tacttgtcga tatagccgcg ggcgcccgcc tcgtaggccc
    17401 ggcgcagccc gcgcggccgg tcgctgcggg tgaggaccgc caacgggcag ccccggccgt
    17461 gcggttcggc cagcgaccgc acctccttca gcaggtccag ggagtccgga cagtccaggt
    17521 cggtgaggat cacatccggt actggtcccg agcccgcgag tgccgggcgt atcgcctccc
    17581 ggtcggcggt cgtcacctct attccctgcc ccgcgccgag cagggaggcc agcgaagcgc
    17641 gccacagagg cacggtgtgg accagcagaa cggttgtcat caagctgccc tcggcatttc
    17701 tctcctggcg cgcgcactac agacgtatcg cagaatgcga tggcgtgtgc gcgtcgggtg
    17761 acgggtctcc agtggagcgc atgaacattc ggccgcgccg acgaattggc ggattcccgt
    17821 gcctgatggg cgcggatggg ggcgttcgga tgtacagcgg gagcgcacgg ggtggtggaa
    17881 cggctgaatc cgactgatga gggcaggccg gggtatacct ttccggccgt gatccgcgcc
    17941 gaaatccggc cgggccgacc tcagttcagc agcgcccggg ccgcctgggc cttgtgccgg
    18001 accgtctcgg ccgtcgtcgg ctcgatggtg tcgagcacct ccgcgtactc ctccatctcc
    18061 gccgccccgc gctggaactc cccgcgctgg accaggagct gggcccgttc gtaccgcagc
    18121 cgggccgggt gcgagggcag cagcagcgag aggtccaccg cccagaggga gacgtccgtg
    18181 cgctcggggc gggcggcggc ccaggcccgg atgttgttca ggatgcgcag cacgatctcc
    18241 agcggccggg ccggtgccag catggacggc tccagccggg cccccgtcgc cccggccacg
    18301 aacagcccgg cctcctcacc ggtcagcggc gcgcctccgg tgaacgggtc gaccagcacc
    18361 ggatgttccg ggtccccgaa gcccacgacg aagtgaccgg gcagcgccac cccgtacacc
    18421 ggggcgccgg cccgccgggc gacctcgatc cagaccaccg agagcaggat cggcagcccc
    18481 cggcggcgcc gcagcacctg ctggaggagc gaggactcca gccgctggta gtccgccggc
    18541 gagccgccga actcgtgccg ctcaccgagc agtccggcca gggcgccggc ccagccgacg
    18601 ggggtgcgga tgccatgggg cagcagcccg gcgagccggt ccagttcgat ctgggccgcg
    18661 tcgatcccgt acgggtccgg ggaggcgtcc cccggccgga ccggacgcgg ctcctccggg
    18721 ccgaccgggc ccgcctccgc gcccagcagc agacagagca gggcgagatc cggccgctcg
    18781 gaccgggcct cctcggcgaa ctgccgccgc cggtcggccg taacggaatc ctgcgcgctc
    18841 atatgcgacc catgcccctg ctcgtccttg ctgccctacc gctgcgggct gtcccacccg
    18901 ctgagcgctg ccccgcctcc gcggcccgcc cggcctccgc cgccgacccg cgattccgcc
    18961 ccctgccgtt gcgggccgcc ccgccggacc cgctgccccc gctctccgct acgcgggccg
    19021 gaagtggtgg taccggtggt gcggggcgaa gcccatgccg tcgtacagcg cccgtgcccc
    19081 ctcattgtcc tcctccacct ggagccaggc cgccgatgcg ccctcgtcca gggcccggca
    19141 ggccagggcc gccatcaccg ccgtggccag tccgcgccgc cggtgcccgg gggcgacctc
    19201 gacggccatg aacccggccc accgcccgtc cacgacacac cgcccgatcg cggcgggcgg
    19261 ctcaccgtca ccggagcccg cccccgcacc ctcgccccgg gccccgcccg ccaccgtggc
    19321 gaaccagacc gaagggccgc tgcccagcac ccgcagcaca tgggggccgg gggtggagaa
    19381 gcgctggtag cgggagagcc aggccgcgtc cggctcgcgg gccagccgca ccgcggacac
    19441 gtccgcgtcc aggtcaccga ccggtgccag cgcggcgatc cgcacctccg ccgtcacctc
    19501 gcgccgccag ccctgccgct ccagctccgc gcagagcgtc tcctgcgcgc cctcggcccc
    19561 ggtcgccgtc tggacgtacg ggggcaggcc ccgctccccg taccactgct cgatccgctc
    19621 gaacgcctcg ccgagcggca gccccggatc cccgagcggc agcacggagt tggcgcggcg
    19681 ggtgaagccg cccgcggcgc gcagccgcca ctcgcccagc ggctcgctct ccaccggctg
    19741 ccaggcgcgc gcggtgacgg cggccagctc cgcgaaggag gcggccgggc cccgcctgcg
    19801 ggccggggcg gcgggcacga ccttgcccgc gaccagggtc gattccagga tgcggaccga
    19861 ctcgccactc ttccgtgtga tcgcgaccac accatcgttc catgatgtga gaacgccgac
    19921 cgtgtcggtg aactccgcgc cggagccgcc ccccgcggaa cgccgcctga ccgagacgcg
    19981 tttgcccacg tcagccggtg tgatgcggac ttccagccgt ccgcccatgg tgaattccac
    20041 agctctgtcc gcccctcctg ttcggatcgt gcccgagaac ggagatacta ggggcgggca
    20101 tcgacgacgc cgcgctcccg cgcgagagcc aacgccctac cgaggaggaa cgacagcgtg
    20161 acctacgtca tcgcgcagcc ttgtgtcgac gtgaaggaca aggcctgcat cgaggagtgc
    20221 cccgtcgact gcatctacga gggccagcgg tccttgtaca tccacccgga cgaatgcgtc
    20281 gactgcggag cctgtgagcc ggtctgcccg gtcgaggcca tcttctacga ggacgacacc
    20341 ccggaggagt ggaaggacta ctacaaggcg aacgtcgagt tcttcgacga cctcggctcg
    20401 ccgggcggtg cctccaagct gggcctcatc gagcgcgacc actccttcat cgccgggctg
    20461 ccgccgcaga accagtaagc ggccgcacca cgagcgcaag cccggtcccg tacggcccgt
    20521 caccgtacgg gaccgaggcg tacccccgta cgacggcgag gcccctcccc ggacgaccgc
    20581 gggacgcgtc cccgtacggt cgcgcggtcc gttccgccta cggccgccgg tccccgaaca
    20641 gcctcagaaa gcagagccgc cccgtgtccg cagtctcctc ccgcctcccg gccttcccct
    20701 gggacaggct cacgccgtac aagaccacgg cccaggccca cccggacggc atcgtggacc
    20761 tctccgtcgg cacgccggtc gacccggtgc ccgaggtgat ccggcgggcg ctcgtcgccg
    20821 ccgccgacag ccccggctat ccgacggtgt ggggcaccga ggccctgcgc gacgcgctca
    20881 ccggctgggt ggagcggcgg ctcggcgcga ccggcgtgac gcacgccaac gtgctgccgg
    20941 tcgtcggctc caaggaactg gtggcctggc tgccgacgca gctcgggctc ggcccgggcg
    21001 acaaggtcgc ctacccgcgc ctcgcctacc cgacgtacga ggtcggcgcc cggctctgcg
    21061 gcgccgagcc cgtcgtctac gacgacccga ccgagctgga cccggccggg ctgaagctgc
    21121 tctggctcaa ctcgccctcc aaccccaccg ggaaggtgct ggccaagcac gagctggtcc
    21181 ggatcgtcgc ctgggcgcgt gagcacgggg tgctcgtctt cagcgacgag tgctacctgg
    21241 agctgggctg ggacgccgaa ccggtctcgg tcctccaccc ggacgtctgc ggcggccact
    21301 acgaggggat cgtcgccgtc cactcgctct ccaagcgctc caacctggcc ggataccggg
    21361 ccgcgttcat cgcgggcgac gcggcggtcc tcggggagct gctgctgatc cgcaagcacg
    21421 gcgggatgat gacgcccgcc cccgtccagg cggcgaccgt cgccgccctc ggggacgaca
    21481 cgcacgtggc cgagcagcgc gcccggtacg ccgaccggcg cctggccctg cgcgccgccc
    21541 tggaggcaca cggcttccgg atcgagcaca gcgaggcgag cctctacctc tgggcgaccc
    21601 gtgacgagcc gtgctgggag accgtggcgt acctcgccca gctgggcatc ctggtggcgc
    21661 ccggcgactt ctacggaccg gcgggcgagt ccttcgtccg ggtggcgttc accgcgaccg
    21721 acgagcgggt ggcggcggcg gtcaagcggc tgtcctgacc accggcgtgc ggaagggccc
    21781 ggggagtgcg cactccccgg gcccttccgc gtactcgcct acgtgacatg tggacgagac
    21841 ccgcgtacgt gaggtgggta cgagacccgc gtacgtgagg tgggtacgag acccgcgtac
    21901 gtgacgtgtg tacgcggcgg tggccgtggc cgtggatcag ccgatcggca gcccgtccag
    21961 cggcaggccg cccttggtga gggcgtcggt gggcaggccg ccctgggtga gcgagtcggt
    22021 cggcaggccg ccggccgcgg cgtcggccac gccgccgagg gcctcgcccg cgctgcccgc
    22081 ggtctggccg gcggtctcct ggacggccgg ggcggccacc cgggcggtct tgccgacggt
    22141 ggcgccggcg gccggcaggg cggtgcccac gaggcggccg ccggtctcgc cggcggcctg
    22201 ggtgccctgg cgggcggcgc tgtccacggt gttgccgagg ccggcaccgt cgagggcggt
    22261 caggccgccg aggtccgggg tctgggggag ctctgcggcg ctcgcggcgc cggccgcacc
    22321 gaccacgggg gccgcacccg cggcgatcag cagcgcggta cgagcgatcc gacgggtcag
    22381 ggggagggac atggtgctcc ttcgacggga agtcaatgat tcgtgcgctt cacgcagttc
    22441 gcgtggtcca tgtggttcac gcggttcatg cgacgcgttc cggtgagccg gacgcactga
    22501 caaccggtcg tgggggaggg aaggttgcgg agaccgaagg taaagagtgg gtaatgcgtc
    22561 cgataatccg cagtggagga acccgggcaa acgatccatt ccgaagtcgt tcgacgaacc
    22621 gtcacttccc ttgggcggca agggaatcga gagggtgcgg gtgcactgcc gcaggggcgg
    22681 cccgagaggg gtggagcgct cggcccaaag gtccgaacgg gcgatggtcc gaactaccgg
    22741 gcgacccgga tggcgaccgc cgc
//
