LOCUS       NZ_ARPF01000001        20294 bp    DNA     linear   CON 18-FEB-2024
DEFINITION  Streptomyces sp. SolWspMP-sol2th B083DRAFT_scaffold_0.1_C, whole
            genome shotgun sequence.
ACCESSION   NZ_ARPF01000001
VERSION     NZ_ARPF01000001.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. SolWspMP-sol2th
  ORGANISM  Streptomyces sp. SolWspMP-sol2th
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 839181)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Improved High-Quality Draft of Streptomyces sp. SolWspMP-sol2th
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 839181)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces sp. SolWspMP-sol2th
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/18/2024 03:17:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,475
            CDSs (total)                      :: 6,400
            Genes (coding)                    :: 6,297
            CDSs (with protein)               :: 6,297
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 31 of 103
            Pseudo Genes (incomplete)         :: 82 of 103
            Pseudo Genes (internal stop)      :: 12 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:24:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 331759
            Orig. end                         :: 352053
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ARPF01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..20294
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20294
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20294
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10294](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10294)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            223..1509
                     /locus_tag="B083_RS1000000136060"
     CDS             223..1509
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (58-414). E-value:
                     8.2e-35. Score: 112.5. Matches aSDomain:
                     nrpspksdomains_B083_RS1000000136060_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="B083_RS1000000136060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_078562450.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.5e-34, bitscore:
                     112.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPADPGPAALDLADLGGPGPAAPGPGVRSWDRLFARHVASDTGDQ
                     ITAILDQSGATDAIALSGGFPHPDTFPARALAESHARVLAQPAALQYGPTPGLPGLRDW
                     FTGWLGRAEGRTPADGELLITSGGMEGLGLITRSLLDPGDRAVVEGPTFFGALVGFQRQ
                     LARVETVPVDGDGLDTDALAELLRGSTGPAPKLLYLVPDHQNPTGLTLSLERRHALIAL
                     ARRYGFLVVEDVAYRELGFDGERHPSLWALAPDVVAQVGTFAKTFTPGIRLGWVVAPAR
                     LTAQLARAKQNTDQCTGAYGQLLLEDYGRSGGFDRQIAASRAFYRRRRDVMTEALAAHL
                     PEEVAYTRPHGGFFSWLTLPGGIDTVALQERALAAKVSYVPGRAFYAGEQGGNSLRLAF
                     SRVPDEQIAEGVRHLSGVLAEAIAATTAR"
     aSDomain        397..1464
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS1000000136060_Aminotran_1
                     _2.1"
                     /evalue="8.20E-35"
                     /label="B083_RS1000000136060_Aminotran_1_2.1"
                     /locus_tag="B083_RS1000000136060"
                     /protein_end="414"
                     /protein_start="58"
                     /score="112.5"
                     /tool="antismash"
                     /translation="IALSGGFPHPDTFPARALAESHARVLAQPAALQYGPTPGLPGLRD
                     WFTGWLGRAEGRTPADGELLITSGGMEGLGLITRSLLDPGDRAVVEGPTFFGALVGFQR
                     QLARVETVPVDGDGLDTDALAELLRGSTGPAPKLLYLVPDHQNPTGLTLSLERRHALIA
                     LARRYGFLVVEDVAYRELGFDGERHPSLWALAPDVVAQVGTFAKTFTPGIRLGWVVAPA
                     RLTAQLARAKQNTDQCTGAYGQLLLEDYGRSGGFDRQIAASRAFYRRRRDVMTEALAAH
                     LPEEVAYTRPHGGFFSWLTLPGGIDTVALQERALAAKVSYVPGRAFYAGEQGGNSLRLA
                     FSRVPDEQIAEGVRHL"
     gene            1633..2310
                     /locus_tag="B083_RS0101425"
     CDS             1633..2310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486984.1"
                     /locus_tag="B083_RS0101425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RraA family protein"
                     /protein_id="WP_232790268.1"
                     /transl_table=11
                     /translation="MPTQPTRSTEPPSAPPGVDALRELLLPEYSPSCLAADAGDRIGAI
                     GGLLTVNPAHRVVGPALTIDLSEQDLVDILPVLGRARPGDVIVLACHGITGMAMWGGLM
                     TTLSQVAGIAGAVVDGAVRDVDEIRDLGFPVWYRTAQPRRCPPADLDGVVQVNVPVTID
                     GVTVRAGDIVVADENGVAVVPPDAAEEVAVSTRELLAKERIVRDLMNAGATLPELLARF
                     GHL"
     misc_feature    2401..2415
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.08"
                     /tool="antismash"
     gene            2434..3903
                     /gene="ahcY"
                     /locus_tag="B083_RS0101430"
     CDS             2434..3903
                     /EC_number="3.13.2.1"
                     /GO_function="GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ahcY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018386384.1"
                     /locus_tag="B083_RS0101430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosylhomocysteinase"
                     /protein_id="WP_050451159.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 3.9e-08, bitscore:
                     28.3, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVALTADSAGSVGGFKVADLSLAELGRKEIRLAEHEMPGLMALR
                     QEFGPQQPLAGKRIAGSLHMTIQTAVLIETLAALGADVRWASCNIFSTQDQAAAAVVVG
                     TEGTVEEPKGSAVFAWKGETLEEYWWCLEQLLTWPDGSGPHSIVDDGGDATLLVHLGAE
                     YEAAGAVPDALADDPEEHRIILDVLRRSLVDNPGRYSEMAKFIVGVTEETTNGVNRLYR
                     LGKEGKLLFTGINVNDAVTKSKFDNRYGIRHSLVDGINRAIDVMIAGKLAVICGYGDVG
                     KGAVASLRGQGARVVVTEADPICALQAAMDGLKVVTLDQVVETGDIFITTTGNRDIIMA
                     DHMARMKHNAVVGNVGHFDNEIDMAGLAQVPGIEKTEIKPQVHEWAFPDGHSIIVLSEG
                     RLLNLGNATGHPSFVMSCSFANQTLAQISLFDPAQNYGTDVYTLPKHLDEKVARLHLPA
                     LDAHLTELTKVQAEYIGVDIEGPFKPDHYRY"
     misc_feature    complement(4246..4259)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.09"
                     /tool="antismash"
     misc_feature    4246..4260
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.85"
                     /tool="antismash"
     misc_feature    complement(4251..4260)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.4"
                     /tool="antismash"
     gene            4272..5570
                     /locus_tag="B083_RS0101435"
     CDS             4272..5570
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486982.1"
                     /locus_tag="B083_RS0101435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_028415349.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 3e-07, bitscore:
                     26.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.3e-09, bitscore:
                     33.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDLARAHANGDRYLLLLGSDILLRERGIVSALRTYPGPVIGMSE
                     TPAAQNANRFFDHVLRADYYDERQALEAVQQFERETGLRPGAVVPIIEMTVHVSVAVAR
                     HYDLPRLSDACLAKVRDKHTMKAAFEAAGVPCARHRLFGTLEELHQAARELDFPLVLKP
                     RDFAGNVGTVRVNGPGELDEAYVYCRDSLLEIAPLYGFEDGRFQAEEFVTSTHEVSVEV
                     ANHRGERTVVAVTDKSKAGAPYFSERGQLVPSADSGNEELRRVALAACAALDIDHGLAH
                     VEVLVDGDRLSVVEVAARPGGDGIMDLIDRVYGFSPYDLHFGSYTDTLDGLPAITAEPA
                     GMGATAFLKAPPGTITEVKPVHDLTPEEVGLYITAQVGDVSRPLTSYLARDGVLECFER
                     GQSDQRAFRAKADELARQRTEQIFTVEAEHDPS"
     gene            5567..6871
                     /locus_tag="B083_RS01000000132755"
     CDS             5567..6871
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="B083_RS01000000132755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_050451160.1"
                     /transl_table=11
                     /translation="MIRGTFRTVAGLNSDLRALFVSTLLFRAGTMAFPFLGAYLLGQER
                     YGVEQVGLVVGAFGLGALVADVGAGVLLGRLRPVTVMLGGCVGYALVLAVVPALSAVPA
                     LLVATLLWGMAFEIYTPASYAQVVAGSSAEQRKIAFSCNRLAINLGMGLGPAVGGLLFT
                     VAPQALFYVNAVCVLAAAGVLLRRSASTRSATTAEAAGPGRLLSPTVRDESRFWTLFVL
                     ALPVHIAYALPPILLSTYVIEGIGLPAYWVSVVFVVNAAAIVLFEVPLNKAMVHMSHLR
                     SLLIGYVLAAAGFALTGLTSSGPLLAVIALLWTCGEMIVFPALLSYVSQLSAPTVINRN
                     VSLYSAGVNVGFMAAPQIGGVLSAGRSPGTPWLAAGTALAAASVLMVAARFSRATWCPD
                     DEHPGADDGPEGQAADGTPKDGQADRAPQSADSTG"
     gene            complement(6914..7714)
                     /locus_tag="B083_RS0101445"
     CDS             complement(6914..7714)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B083_RS0101445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028415350.1"
                     /transl_table=11
                     /translation="MVTPAGSAGLTGCLEEMDRRGLIPDGCLAVCCVGPAARGWADEGG
                     TYDFHVVSTGPWTGEGARALPVRLSPAEVPSLALSVAGRRWEITYWLEGQVRQVLAKVT
                     RERFEGGGTAVGVLSDAEELFLERMSAPLALSGTEWAKECERRIGGSAFRALVTTRSLA
                     AADRAIEDAGRRLAARDVPSAVLAARSALGHTVDALLESESDFGSRAPRRRARRLRETR
                     PRALPFAEYWAMETMRSYDPARPEEWVTTVVQRCRDLAFEVEIS"
     gene            complement(7708..8277)
                     /locus_tag="B083_RS1000000134430"
     CDS             complement(7708..8277)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024736.4"
                     /locus_tag="B083_RS1000000134430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_078562451.1"
                     /transl_table=11
                     /translation="MTHQGNPLPPLRRTNSTLPEARVPGPRVPLPGAGRFTWLAPMALW
                     PLARRHLPRPAVRPQGGGSQRADDEATFAAILFVLVSGVPWRALPRAFTVSWQNTHRRF
                     TQWSAAGLWDQLRESAHRQHTPGQSRELVQWAEAVCELAEERLNRTAPPAAAARRRAGS
                     LQPRLRVREPDDFTVRLFGPGRDSAW"
     misc_feature    complement(8254..8256)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8274..8480)
                     /locus_tag="B083_RS1000000136065"
     CDS             complement(8274..8480)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B083_RS1000000136065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028415351.1"
                     /transl_table=11
                     /translation="MTTAEGGQVDSAPTQTWLRAAAVRIDRQQEPPTRQDLAHSDGGHG
                     DDTRCGLPAARVLRPLTTALERT"
     misc_feature    complement(8683..8696)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    8691..8707
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.76"
                     /tool="antismash"
     gene            complement(9031..9807)
                     /locus_tag="B083_RS0101460"
     CDS             complement(9031..9807)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486978.1"
                     /locus_tag="B083_RS0101460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_028415352.1"
                     /transl_table=11
                     /translation="MVESVKRAVRIIKELTGASPRLGVTELADRVGVSKSAMHGLLRTL
                     ESDGLVVQDQESGKYRLGPALVTFGNAYLDTHELRTRALTWSNLLATRTDEAVWVGVLV
                     HDDVLVIHHVCRPGNVAQPLETGATLPWSTTALGKAIVAFSPEELRTRLLSRPPAALTG
                     HSVTEPEVLEAQLAQAREVGYAVEKQEATLGDAGIAAPIFDRTGCAAGAIGLVGPVERL
                     LDERHRQGCSIATRETARSLSRELGAHRFGNRVASF"
     gene            complement(10001..10294)
                     /locus_tag="B083_RS01000000132765"
     CDS             complement(10001..10294)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="B083_RS01000000132765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_018486977.1"
                     /sec_met_domain="PqqD_RRE (E-value: 6.9e-10, bitscore:
                     34.1, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.2e-13, bitscore: 45.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.8e-09,
                     bitscore: 31.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGETEIELTPASVLQRRVEARARRYRGRMYVAVREHALELDEVAQ
                     AIVRRIDGTSTLRGIAAVVAEEYGVPAENATGDTVEFAAQLLAHGVVEVVPG"
     aSDomain        complement(10013..10180)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B083_RS01000000132765_Stand_Alone_Las
                     so_RRE.1"
                     /evalue="2.30E-10"
                     /identifier="RREFam002.1"
                     /label="B083_RS01000000132765"
                     /locus_tag="B083_RS01000000132765"
                     /protein_end="94"
                     /protein_start="38"
                     /score="31.4"
                     /tool="antismash"
                     /translation="ELDEVAQAIVRRIDGTSTLRGIAAVVAEEYGVPAENATGDTVEFA
                     AQLLAHGVVEV"
     aSDomain        complement(10016..10261)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B083_RS01000000132765_PqqD_RRE.1"
                     /evalue="2.70E-11"
                     /identifier="RREFam006.1"
                     /label="B083_RS01000000132765"
                     /locus_tag="B083_RS01000000132765"
                     /protein_end="93"
                     /protein_start="11"
                     /score="34.1"
                     /tool="antismash"
                     /translation="SVLQRRVEARARRYRGRMYVAVREHALELDEVAQAIVRRIDGTST
                     LRGIAAVVAEEYGVPAENATGDTVEFAAQLLAHGVVE"
     misc_feature    complement(10361..10376)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.66"
                     /tool="antismash"
     misc_feature    10860..10875
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.07"
                     /tool="antismash"
     gene            complement(10861..12609)
                     /locus_tag="B083_RS0101470"
     CDS             complement(10861..12609)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608327.1"
                     /locus_tag="B083_RS0101470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="WP_232790269.1"
                     /transl_table=11
                     /translation="MPAAVAVASVLLLGAAAPGQPPRTGGAVAGTEPVGRMPLGPADVP
                     TRTRPADLLAPGVTYRKYWQGEASDAWSVWVRHPQTGTETFGSWADADRLAKDLDAAGF
                     TARVDVFTVPESADTDSRVVGYGVRVGRFAADRREDAVQARQALADAGFGRSRIFFTAE
                     DGSPSRGPWQVRVITVAPSARVTLKAVHGKDVQGSETVRQLAAESGALVAVNGSEFDID
                     SPNNADFGGFEGVPQGLYLQNNVLLGTPNNGRTALLLEGLQGRAAVDEISSETRITAPD
                     GAVRVVDGIHRPAGHVLGCGGVGNDYRASSRTRTLQPWRNTTCHDPDEIVVFRPEWGAA
                     TPTPVRRGDSWTDPVTGWQAQWYADQAEFLAQTVDVVMDGNWVVKQLRTPAGGPIPPGG
                     RVLQGIGEGAAWLRAHSEVGKAFKPGSTVRGRDGRPVTTPALSAVAGGTPALVRGGEVW
                     LNPAANGMAQVSCVPADLAPGQKCRANNTLLQRHARTLAGVTAAGELLLVTIDGRDPAL
                     SVGATLPEAAAVMKWLGAREAVGLGSGGDTTLIAGNTLYNRPVDDWGGPLRERRVSNAV
                     VVVEKP"
     gene            12882..14150
                     /locus_tag="B083_RS0101475"
     CDS             12882..14150
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064356.1"
                     /locus_tag="B083_RS0101475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_028415354.1"
                     /transl_table=11
                     /translation="MTDTTEQPARRPRIFADLTPLRAYPDYRRLWFGNTVSWIGQGMTA
                     LAVSLQVYDITGSAFSVGLIGFCSLVPLVVFGLYGGAVADTVDRRKLGLFSAAGSFLLA
                     LVLALATFAGAENVGLLYAIVALQAVCFALNAPARSSMIARLLPPEQLPAANALSSMTT
                     TTGALVGPMLGGLIVGWWGYRAAYTVDAVTFTASLYAMWRLPSMLPDRTAEGEARKRAS
                     VTDGLRFLGTRPNLRMTFFTDLCAMVLAHPRALFPVVAVVWYGGDARTTGLLVAAPALG
                     ALLGGVFSGWLGRIRRHGLAVLLAVGSWGAAIAVFGLTRHLWLGLLFLALAGCADTVSM
                     VFRNTMLQAAVPDEMRGRLQGVFIVVVAGGPRLGDFLAGSVADLTSPAVAVVGGGAACV
                     VAVGLLALKWRGFARYDARDPQP"
     gene            complement(14181..15656)
                     /locus_tag="B083_RS0101480"
     CDS             complement(14181..15656)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486974.1"
                     /locus_tag="B083_RS0101480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_232790270.1"
                     /transl_table=11
                     /translation="MSGDAPASGGFPLAGGSLASGGSPESGDASVGAPSGATPRATARE
                     AIALLTGGAGFTEHRPPSPRTLPPDGPLGWAGYDAARARAAERTGEDESVVYGTGVAGG
                     RECVLLAFEFGFLGGSLGLLTGDRLEAAYDLALARRLPLVALVATGGSRMQEGMVALTQ
                     LQRVAAASTRLRAAGLPQIAVVRDPTTGGGWATVGAGADVVLALPGAQIGFAGSRVRPP
                     DADPYAYGAEGQSAAGQVDAVVPGPELPRTVGLWLRALGAGEEAAGTGDGPAAAPLPRA
                     QAPSSAGLPGSGREAVERARAVGRPRARAYLDDYFAERLPLHGDRSGGTDPGLLSGFGL
                     RADGRAVAYVAQCGTPTRPAGYRAAARTIRLADRLGVPVLTLVDTPGAANDAEAERAGQ
                     GAAIADTFAAIAAARVPVTTLVIGEGGSGGALALAAPGNTHVTADSYFSVIAPELAAAI
                     LKRPPEETGATADQLRLRPQDLVELGIARSVVR"
     gene            complement(15646..17256)
                     /locus_tag="B083_RS0101485"
     CDS             complement(15646..17256)
                     /NRPS_PKS="Domain: AMP-binding (16-441). E-value: 2.8e-84.
                     Score: 275.0. Matches aSDomain:
                     nrpspksdomains_B083_RS0101485_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761518.1"
                     /locus_tag="B083_RS0101485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_028415356.1"
                     /sec_met_domain="AMP-binding (E-value: 5.8e-92, bitscore:
                     303.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLLLPALQSPTGPTASREAVRFGDLSLTYGRLAGASAALAARIA
                     DAGRVAVWATPTAETVIAVVAALRADVPVVPLNPRTGERELAHILADSEPTAVLAGRAD
                     ELPPALEKVRRVTVDARAETGSATEYAEGGGGAAAYAEGRGDGAAYAEGRGGGAAYAYG
                     GGGAPADGGAPGPGEGDPESPALIVYTSGTTGPPKGAVLPRRAVAASLDALEDAWGWTG
                     DDVLVHALPLFHVHGLILGVLGPLRRGGSLRHLGAFSAAGVARELGSGGTMLFGVPTMY
                     HRLAEVLDAPAGTAGRDALAGALAGARLLVSGSAALPVHDHERVAAATGRRVIERYGMT
                     ETLMNTGIRADGVPRPGTVGPPLAGVELRLVEEDGTVLEGPEAIGEIQVRGPNLFTGYL
                     NRPDATAAAHTADGWFRTGDVGTVDTDGYVTIVGRKATDLIKSGGYKIGAGEIENVLLG
                     HPGVREAAVTGEADPDLGERVVAWVVPADPDSPPAAEELADLVGGQLAPHKRPRTVRYL
                     DALPRNDLGKIMKRSLHVR"
     aSDomain        complement(15934..17208)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B083_RS0101485_AMP-binding.1"
                     /evalue="2.80E-84"
                     /label="B083_RS0101485_AMP-binding.1"
                     /locus_tag="B083_RS0101485"
                     /protein_end="441"
                     /protein_start="16"
                     /score="275.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="SREAVRFGDLSLTYGRLAGASAALAARIADAGRVAVWATPTAETV
                     IAVVAALRADVPVVPLNPRTGERELAHILADSEPTAVLAGRADELPPALEKVRRVTVDA
                     RAETGSATEYAEGGGGAAAYAEGRGDGAAYAEGRGGGAAYAYGGGGAPADGGAPGPGEG
                     DPESPALIVYTSGTTGPPKGAVLPRRAVAASLDALEDAWGWTGDDVLVHALPLFHVHGL
                     ILGVLGPLRRGGSLRHLGAFSAAGVARELGSGGTMLFGVPTMYHRLAEVLDAPAGTAGR
                     DALAGALAGARLLVSGSAALPVHDHERVAAATGRRVIERYGMTETLMNTGIRADGVPRP
                     GTVGPPLAGVELRLVEEDGTVLEGPEAIGEIQVRGPNLFTGYLNRPDATAAAHTADGWF
                     RTGDVGTVDTDGYVTIVGRKATDLIK"
     CDS_motif       complement(16033..16113)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0101485_0002"
                     /evalue="2.60E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="B083_RS0101485"
                     /protein_end="408"
                     /protein_start="381"
                     /score="29.4"
                     /tool="antismash"
                     /translation="EAIGEIQVRGPNLFTGYLNRPDATAAA"
     CDS_motif       complement(16651..16704)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B083_RS0101485_0001"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="B083_RS0101485"
                     /protein_end="202"
                     /protein_start="184"
                     /score="19.9"
                     /tool="antismash"
                     /translation="ALIVYTSGTTGPPKGAVL"
     misc_feature    complement(17395..17409)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.02"
                     /tool="antismash"
     misc_feature    complement(17396..17411)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.87"
                     /tool="antismash"
     gene            complement(18066..19307)
                     /locus_tag="B083_RS0101490"
     CDS             complement(18066..19307)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486972.1"
                     /locus_tag="B083_RS0101490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_028415357.1"
                     /transl_table=11
                     /translation="MNSAVKQPPEPPDVPAPAAAAAAAPSAAAYRNLVMATIGFALTFW
                     AWNLIAPMSGDYKDRLGLSSFQQSLLVAVPVLVGSLGRIPVGALTDRYGAKLMFPLVSA
                     LTIVPVLLLIPARNSYGAMLAVGFLLGLGGTTFAIGVPLVNSWFPPARRGFALGVFGMG
                     MGGVALSGYFTPRIAKHGDNLPFLVVAGALVVFALLAAVLVSDHPGRKVPTDTLAHRLG
                     DAARLRVTWELSALYAIGFGGIVAFGVYLPTYLKTWYEMSPTEAGTKAAGFALVTVVFR
                     PIGGWLSDRVHPALVTAGALLLAALMAVVQAFEPPLNPTGTIALLAMAAGLGTASGSVF
                     ALVSQVTPQAKVGSVTGIVGAMGGLGGFVPPLVMGAIYSAKDSYAIGFMLLSDLALAGC
                     VYAYARMRNLQRGG"
     gene            19471..19902
                     /locus_tag="B083_RS0101495"
     CDS             19471..19902
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449417.1"
                     /locus_tag="B083_RS0101495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_028415358.1"
                     /transl_table=11
                     /translation="MDRLDREILGILQEDARISYRDLGVRVGLSANAAGDRVRRMRKDG
                     VIRGFTVIVDPAADTRSGLVVFIDVTLRLDTTNEEFERSVLMLPGITEVVHVTGGHDYL
                     IRATAADPVALDSLLRRLKKEAGVAHSTTRIALRAAPKH"
     misc_feature    19944..19954
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
ORIGIN
        1 gctccggagg cccgctcgtc cactaccgcc gcgacctgcg cgccctggcg ggaccggcac
       61 cgacggcagc gggtgacccg gaggccgtct ccgtacgcga tcgggcaccc gccccggcct
      121 ccgtaccgcc ccaggccctc gcacccgccc ccgcacctca cccggccccc gatccccgcc
      181 gcgacccgaa cctcggcacc gaccgtgaag agaggcccgc acatgcccgc tgaccccggc
      241 cccgccgccc tcgacctcgc cgacctcggc ggtcccggcc ccgccgcccc cggccccggc
      301 gtccggagct gggaccggct gttcgcccgc catgtggcga gcgacaccgg cgaccagatc
      361 accgccatcc tcgaccagtc cggcgccacc gacgccatcg ccctctcggg cggcttcccg
      421 caccccgaca ccttccccgc gcgggcgctg gccgagagcc atgcccgggt gctcgcgcag
      481 cccgccgcgc tccagtacgg gcccaccccc gggctccccg ggctgcgcga ctggttcacc
      541 ggttggctgg ggcgggccga ggggcggacg cccgccgacg gcgaactgct catcaccagc
      601 ggcgggatgg agggcctcgg cctcatcacc cgcagcctcc tcgacccggg cgaccgggcc
      661 gtggtcgagg gccccacctt cttcggcgcc ctcgtcggct tccagcggca gctggcccgg
      721 gtggagaccg tgccggtcga cggggacggg ctggacaccg acgccctggc cgagctgctg
      781 cgcgggtcca ccgggccggc gcccaagctc ctctacctcg tcccggacca ccagaacccc
      841 accggcctca ccctctccct ggagcgccgc cacgccctga tcgcgctggc ccggcggtac
      901 gggttcctcg tcgtcgagga cgtcgcctac cgcgagctgg gcttcgacgg ggaacgccac
      961 cccagcctct gggcactcgc ccccgacgtc gtggcccagg tcggcacctt cgccaagacc
     1021 ttcaccccgg gcatccggct cggctgggtc gtcgccccgg cccgcctcac cgcccaactg
     1081 gcccgcgcca agcagaacac cgaccagtgc accggcgcct acgggcagct gctgctggag
     1141 gactacggga ggtccggcgg gttcgaccgc cagatcgccg cctcccgggc cttctaccgg
     1201 cgccgccggg acgtgatgac cgaggccctc gccgcccatc tgcccgagga ggtcgcgtac
     1261 acccggccgc acggcggctt cttcagctgg ctcaccctgc ccgggggcat cgacaccgtg
     1321 gcgctccagg agcgggcgct ggccgccaag gtcagctatg tgccggggcg cgccttctac
     1381 gccggggagc agggcggcaa cagcctccgc ctggcgttca gccgggtgcc ggacgagcag
     1441 atcgccgagg gcgtacgcca tctgtccggc gtcctcgccg aggcgatcgc cgccaccacc
     1501 gcccgctgac caccgccccc acggccccga caccgcgcgc gggccaccga ccaccggcca
     1561 ctgaccactg accgctgagc actgaccgct gtcccattcc tttccaccct catgaaggag
     1621 aagggcccct ccatgcccac ccagcccacc cggtccaccg agccgccgtc cgccccgccc
     1681 ggcgtcgacg ccctgcgcga gctgctgctc cccgagtaca gcccgagctg cctggccgcc
     1741 gacgccgggg accgtatcgg cgccatcggc gggctgctca ccgtcaaccc cgcccaccgg
     1801 gtcgtcggcc ccgccctgac catcgacctc tccgagcagg acctggtcga catcctcccg
     1861 gtgctcgggc gggcccggcc cggggacgtc atcgtgctgg cctgtcacgg gatcaccggg
     1921 atggcgatgt ggggtggcct gatgacgact ttgtctcagg tggcggggat cgccggagcc
     1981 gtcgtcgacg gggccgtccg ggacgtggac gagatacgcg acctcggctt ccccgtctgg
     2041 taccgcaccg cccagccgcg ccgctgcccg ccggccgacc tggacggtgt cgtgcaggtc
     2101 aacgtgccgg tgacgatcga cggggtgacg gtacgggcgg gtgacatcgt ggtcgccgac
     2161 gagaacgggg tggccgtcgt gccgcccgac gcggcggagg aagtagctgt ttcaacaagg
     2221 gagttgctgg caaaggagcg gatcgtgcgc gatctgatga acgcgggggc gacgcttccg
     2281 gaactactgg cgcgattcgg ccacctgtaa tcggccgagg tatcgcgtcc acgagcggga
     2341 atggcatgct cgttccgagg ccacatgaga gagttggacc caaaagccgc tgacgtttcg
     2401 tcaccagcat ttccagacag ggagaatgac agcatggctg ttgcgttgac cgcggacagt
     2461 gccgggtcgg tcgggggatt caaggtcgcc gatctctcac tcgccgagct gggccgcaag
     2521 gagatccgtc tcgccgagca cgagatgccc ggactgatgg ccctgcggca ggagttcggc
     2581 ccgcagcagc cgctggccgg aaagcgcatc gccggctctc tccacatgac catccagacc
     2641 gccgtcctga tcgagacgct cgccgcgctc ggcgccgacg tccgctgggc cagctgcaac
     2701 atcttctcca cccaggacca ggcggccgcg gccgtcgtcg tgggcaccga gggcacggtg
     2761 gaggagccca agggcagcgc cgtcttcgcc tggaagggcg agacgctgga ggagtactgg
     2821 tggtgcctgg agcagctgct gacctggccc gacggctccg gcccgcactc gatcgtcgac
     2881 gacggcggtg acgccaccct gctggtccac ctgggtgccg agtacgaggc ggcgggcgcc
     2941 gtcccggacg cgctcgccga cgacccggag gagcaccgga tcatcctcga cgtgctccgc
     3001 cgctcgctcg tggacaaccc gggcaggtac tcggagatgg cgaagttcat cgtcggcgtc
     3061 accgaggaga ccaccaacgg cgtcaaccgg ctctaccgcc tcggcaagga gggcaagctc
     3121 ctcttcaccg ggatcaacgt caacgacgcg gtgaccaaga gcaagttcga caaccgctac
     3181 ggcatccgcc actcgctggt cgacggcatc aaccgcgcca tcgacgtcat gatcgccggg
     3241 aagctcgccg tgatctgcgg ttacggcgac gtcggcaagg gcgccgtggc gtccctgcgc
     3301 ggccagggcg cgcgtgtcgt ggtcaccgag gccgacccga tctgcgcgct ccaggcggcc
     3361 atggacggtc tgaaggtcgt cacgctcgac caggtcgtcg agaccggtga catcttcatc
     3421 accaccaccg gcaaccgcga catcatcatg gccgaccaca tggcccggat gaagcacaac
     3481 gccgtcgtcg gcaacgtggg ccacttcgac aacgagatcg acatggccgg cctcgcgcag
     3541 gtgccgggca tcgagaagac cgagatcaag ccgcaggtcc acgagtgggc cttccccgac
     3601 gggcactcga tcatcgtgct cagcgagggc cgcctgctca acctgggcaa cgcgaccggc
     3661 cacccgagct tcgtgatgtc ctgctcgttc gccaaccaga ccctggcgca gatctcgctc
     3721 ttcgacccgg cgcagaacta cggcaccgac gtctacaccc tgcccaagca cctggacgag
     3781 aaggtggcgc gcctgcacct ccccgccctc gacgcccacc tcaccgaact caccaaggtc
     3841 caggccgagt acatcggcgt ggacatcgaa ggtcccttca agccggacca ctaccgctac
     3901 tgacgggtcg gccccgcctt cgggccgatc cgcggacgac acccgagggc cggcctcaca
     3961 ccttcggccc gagggcgggc ccggcacctt cggtccgagg gtcggcccga caccttcgga
     4021 ccgatccacc ggaccggtcc accgggccga tccaccgggc cgatccgccg ggccgacctc
     4081 cggacgaccg agtgagaggc gtccgccgcc ggttccaccc ggcggcggcg ccccgtggcg
     4141 ggccgtgacc cgaccggccg ccacagccac ccgcgcacga cccgcgcggc ctttcccgaa
     4201 atacggcctt cgcccctccg cggcacgccg tcttctgtcg aagtcctctt tcgaaaaatg
     4261 ggggaaccac cgtgttcgat ctcgcgcgcg cccatgccaa cggcgaccgc tatctgctgc
     4321 tgctcggctc cgacatcctg ctccgtgaac gcggcatcgt ctcggcgctg cggacctacc
     4381 ccggcccggt gatcgggatg agcgagaccc cggccgcgca gaacgccaac cgcttcttcg
     4441 accacgtcct gcgcgccgac tactacgacg agcgccaggc cctcgaagcc gtccagcagt
     4501 tcgagcgcga gaccgggctg cggcccggcg cggtggtgcc gatcatcgag atgaccgtgc
     4561 acgtctccgt cgccgtcgcc cgccactacg acctgccccg gctctccgac gcctgcctgg
     4621 ccaaggtccg cgacaagcac acgatgaagg cggccttcga ggcggccgga gtgccctgcg
     4681 cccgccaccg cctcttcggc accctggagg aactccacca ggcggcccgg gagctggact
     4741 tcccgctggt gctcaagccg cgcgacttcg ccggcaacgt cggcaccgtg cgggtcaacg
     4801 gccccggcga gctggacgag gcgtacgtct actgccgcga ctccctgctg gagatcgccc
     4861 cgctgtacgg gttcgaggac ggccgcttcc aggccgagga gttcgtcacc tccacccacg
     4921 aggtctccgt cgaggtcgcc aaccaccgcg gtgagcggac cgtcgtcgcc gtcaccgaca
     4981 agtccaaggc gggcgccccc tacttcagcg agcgcggcca gctggtgccg agcgccgact
     5041 ccggcaacga ggagctgcgc cgggtcgccc tggccgcctg cgccgcgctc gacatcgacc
     5101 acggactggc ccatgtcgag gtcctggtcg acggcgaccg gctgagcgtc gtcgaggtgg
     5161 cggcccggcc cggcggcgac gggatcatgg acctgatcga ccgcgtctac ggcttcagcc
     5221 cctacgacct ccacttcggc tcgtacacgg acaccctgga cggcctgccc gccatcaccg
     5281 ccgagcccgc cggcatgggg gccacggcct tcctcaaggc gccgcccggc acgatcaccg
     5341 aggtcaagcc ggtccacgac ctgacccccg aggaggtcgg cctctacatc accgcccagg
     5401 tgggcgacgt ctcccggccg ctgacctcgt acctcgcgcg cgacggcgtc ctggagtgct
     5461 tcgagcgggg ccagagcgac cagcgggcct tccgcgccaa ggccgacgag ctggcccggc
     5521 agcgtacgga gcagatcttc accgtcgagg cggagcacga cccgtcatga tccgcggcac
     5581 gttccgcacg gtcgccgggc tcaacagcga tctgcgggcc ctgttcgtct ccaccctgct
     5641 cttccgggcg gggacgatgg ccttcccctt cctcggcgcc tatctgctcg gacaggaacg
     5701 ttacggcgtc gaacaggtcg gcctggtcgt cggcgccttc ggcctcgggg cgctcgtcgc
     5761 cgacgtgggc gcgggggtgc tgctgggacg gctgcggccg gtcacggtga tgctcggcgg
     5821 ctgcgtcggc tacgccctgg tgctggccgt cgtgcccgcg ctctccgccg tgcccgcgct
     5881 cctcgtcgcg accctgctct ggggcatggc cttcgagatc tacacgcccg ccagttacgc
     5941 gcaggtcgtg gcgggttcct cggccgagca gcggaagatc gccttctcct gcaaccggct
     6001 ggcgatcaac ctcggcatgg ggctcggccc ggcggtcggc ggtctgctct tcaccgtggc
     6061 tccgcaggcg ctgttctacg tcaacgccgt ctgcgtcctc gccgccgccg gggtgctgct
     6121 gcgccgctcc gcctccaccc ggtcggccac gaccgccgag gcggccggac cgggcaggct
     6181 gctctcgccc accgtccgcg acgagtcccg gttctggacc ctgttcgtcc tggccctgcc
     6241 ggtgcacatc gcgtacgcgc tgccgccgat cctgctgagc acgtacgtca tcgagggcat
     6301 cgggctgccc gcctactggg tcagtgtcgt cttcgtggtc aacgcggcgg cgatcgtgct
     6361 gttcgaggtg ccgctgaaca aggccatggt ccacatgtcc cacctgcggt cactgctcat
     6421 cggctacgtg ctggcggcgg ccgggttcgc cctcaccggg ctcacctcca gcgggccgct
     6481 gctggcggtg atcgcgctgc tctggacctg cggggagatg atcgtcttcc cggccctgct
     6541 cagctacgtc tcccagctct ccgccccgac ggtgatcaac cgcaatgtga gcctgtactc
     6601 ggcgggcgtc aacgtcggat tcatggcggc gccgcagatc ggcggggtgc tctcggccgg
     6661 ccgttcgccg ggcaccccct ggctggccgc cgggacggcg ctggccgcgg cgagcgtgct
     6721 gatggtggcc gcccgcttct cccgggccac ctggtgcccg gacgacgagc atccgggcgc
     6781 cgacgacggc ccggaggggc aggcggcgga cgggacgccg aaggacggac aggccgaccg
     6841 ggcgccccag tcggcggact cgacgggctg acggaggggg tggtccggga accccggacc
     6901 acccccggcc ccctcaggag atctccacct cgaacgccag gtcccggcac cgctgcacca
     6961 ccgtcgtcac ccactcctcc ggccgcgccg gatcgtagga gcgcatggtc tccatcgccc
     7021 agtactccgc gaacggcagc gccctcggcc gggtctcccg cagccgccgg gcccgccggc
     7081 gcggcgcccg ggagccgaag tcgctctcgc tctccagcag cgcgtccacc gtgtgcccca
     7141 gcgccgaacg ggccgcgagc accgcgctgg ggacgtcccg ggcggccagc cggcgccccg
     7201 cgtcctcgat ggcccggtcg gccgcggcga gcgaacgggt ggtcacgagg gcccggaacg
     7261 cggagccgcc gatccgccgc tcgcactcct tcgcccactc cgtgccgctg agcgcgagag
     7321 gggcgctcat ccgttccagg aacagctcct cggcgtcgct cagcaccccg accgccgtgc
     7381 cgccgccctc gaaccgttcc cgggtgacct tggcgagcac ctgccgtacc tggccctcca
     7441 gccagtacgt gatctcccag cgccggcccg ccaccgacag cgccagcgac gggacttcgg
     7501 ccggggagag ccgcacgggc agcgcgcggg cgccctctcc ggtccacgga ccggtggaga
     7561 ccacgtggaa gtcgtacgtg ccgccctcgt cggcccagcc gcgagcggcg ggtccgacgc
     7621 agcagaccgc gaggcagccg tccggtatca gcccgcggcg gtccatctcc tccaggcagc
     7681 cggtcagtcc ggcgcttccg gccggggtca ccacgccgag tcccggccgg ggccgaagag
     7741 gcggacggtg aagtcgtcgg gctcgcgcac ccgcagacgc ggctgcaggc tcccggcccg
     7801 ccgccgcgcg gccgccgccg ggggagccgt ccggttcagc cgctcctcgg ccagctcgca
     7861 gacggcctcc gcccactgca ccagctcgcg cgactgcccc ggggtgtgct gccggtgggc
     7921 gctctcccgg agctggtccc acagccccgc cgcgctccac tgggtgaacc ggcggtgggt
     7981 gttctgccag gacaccgtga acgcccgggg cagggcccgc cagggtacgc cgctgacaag
     8041 gacgaacagg atggcggcga aggtcgcctc gtcgtcggcc cgttggctgc cgccgccctg
     8101 cggacggacc gccgggcggg gcagatgccg gcgggccagc ggccacaggg ccatcggggc
     8161 gagccaggtg aaccggcccg cgccggggag ggggacgcgg gggccgggca ccctcgcctc
     8221 cgggagggtg ctgttcgtcc gccgcagcgg gggtaacgga ttgccttggt gggtcatgtc
     8281 ctctccaggg cggtcgtgag cgggcggagg acgcgcgcgg ccgggaggcc gcaccgcgtg
     8341 tcgtcaccgt ggccaccgtc gctgtgggcc aggtcctgtc gagtgggcgg ttcctgctgt
     8401 cggtcgatgc gtacggccgc tgcacgcagc caggtctgcg tcggtgcgga gtccacctgt
     8461 cctccctctg ccgtggtcat cggctgctct ccggccccgt ccgtcggacg accctgtcgt
     8521 gaagacgggc atgccgccgg gtgaggttgc ctcgggaacg gcgtgctgcg ttccggcgcg
     8581 gtcgatcggc ttcctgacgg tggccccctc cacccgcggt cgctcggggt gagcggccga
     8641 cctgcctgcc ggagcattga atcgaacgat gttcttcggt gcagaacgct tgctcgaaag
     8701 ctaggcgcgg tccaaatggc gtgtcaagca acggctgttg ccggtggacg caccggtgca
     8761 tacctcaacg gacacggacg gaccggatgc gcgcgggctc ctggaatcgg ccgggattgg
     8821 tcggcgtggg gcgtgggtag tgtcggtcgg ggccgcccgg ccggggtccc ggtggaaccg
     8881 gttccggccg gtccgcgagg gggcggatcg gggtggtggc agcgggtcag gggtggtgcg
     8941 gacggggcgg gccgagcgtg acgggggcgt ggtgatgggc ggtggcggcg gcttcggcgg
     9001 gccggtcggc ggaccgggcg ggggagtggt tcagaaggag gcgacccggt tgccgaaccg
     9061 gtgggcgccg agttcgcgcg agaggctgcg ggccgtctcg cgggtcgcga tcgaacagcc
     9121 ctgccggtgc cgttcgtcca gcaggcgttc gacggggccg acgaggccga tggccccggc
     9181 cgcgcacccg gtgcggtcga agatgggggc cgcgatgccc gcgtcgccga gcgtcgcctc
     9241 ctgcttctcc acggcgtagc cgacctctct ggcctgcgcc aactgcgctt ccagcacctc
     9301 gggttcggtc accgagtggc cggtcagcgc agcgggcggg cggctgagca ggcgggtccg
     9361 cagctcctcg ggggagaagg ccacgatggc cttgcccagc gcggtggtgc tccagggcag
     9421 cgtggccccg gtctccagcg gctgcgccac gttccccggc cggcagacgt ggtggatcac
     9481 caggacgtcg tcatggacca gcaccccgac ccagaccgcc tcgtcggtcc gggtggccag
     9541 caggttggac caggtgaggg cgcgggtgcg cagctcgtgc gtgtccaggt aggcgttgcc
     9601 gaaggtcacc agggcgggtc ccagccggta tttgcccgac tcctggtcct gcaccaccag
     9661 gccgtccgac tccagggtgc ggagcaggcc gtgcatggcc gatttcgaca ccccgacccg
     9721 gtcggcgagt tcggtgaccc ccagtcgcgg ggaggccccc gtcagctcct tgatgatgcg
     9781 tacggcgcgc ttgaccgact cgaccatggg cccacccctg ttcggtatga gtgaacactg
     9841 ttctctttga cggcgtcaat gttcacgttc ttgtacggca tggccatggt gccctacccg
     9901 tacggaaccg ggttgccggg gtggtggcgc caccggcccc gacccggggg cggccgcctc
     9961 ccgggagcgc ctcccgggtc cgcccggcgc tgcttcgggg tcacccgggg acgacctcga
    10021 ccaccccgtg cgcgaggagt tgggcggcga actcgaccgt gtcgccggtg gcgttctcgg
    10081 ccgggacgcc gtactcctcc gccaccacgg cggcgatccc gcgcagcgtc gacgtaccgt
    10141 cgatccgccg gacgatggcc tgcgccacct cgtccagctc caacgcgtgc tcccgcacgg
    10201 ccacatacat ccgcccccgg taccggcgcg cgcgggcctc cacccggcgc tgcagaacac
    10261 tggccggtgt cagctcgatc tcggtctccc ccatggctcc cccatcgtgt gtgctccacc
    10321 cggtgaatcc tgatgcccgg gataggaatg caaccggcgg ccgaccggac cgtcaaggtc
    10381 cacctgagac agccaaccgc ccgaccggcc cgtacggttc ggctccgccg caggtggggc
    10441 gcggggcgcg cgggggaggg gacggccggg ggcgccggac gggcgcggcg agatgagaca
    10501 cggccactcc gaccacatga gacacattgc cttcccggca gccccctcgc ggccggggcc
    10561 ccgcgcgccg gccgcgaggc atcggccccg cgccacccgg gctccgcgcc acccgggctc
    10621 cgggctctgg cctctgggcc tcccggcccc tcagcctccc gacccctcag ccccggaggc
    10681 ccctcgcccc cggctccccg ggctccggcc tcccgactcc ggtccctcag ccccggaggc
    10741 ccctcggctc cggcctcccg gctccgggct ctggcttccc ggctccggtc tccgggctcc
    10801 ggcctcgcgg ctccggaggc cccaggctca ggccctcaac cccggcccct cgcccccggc
    10861 tcacggcttc tcgacgacga ccacggcgtt gctcacgcgt cgctcgcgca ggggcccgcc
    10921 ccagtcgtcc accggccggt tgtagagcgt gttcccggcg atgagggtgg tgtcgccgcc
    10981 gctgccgagc cccaccgcct cccgggcgcc cagccacttc atcaccgcgg ccgcctcggg
    11041 cagcgtcgct cccacgctca gcgccgggtc gcggccgtcg atggtgacga gcagcagctc
    11101 accggcggcg gtgacccccg cgagcgtgcg ggcgtgacgc tgcagcagcg tgttgttggc
    11161 acggcacttc tgccccggtg cgaggtcggc cggtacgcag gagacctggg ccatcccgtt
    11221 ggcggccggg ttcagccaca cctcgccgcc ccgtaccagt gccggcgtgc cgcccgccac
    11281 cgccgagagc gccggggtgg tcacgggcct gccgtcccgg ccccggaccg tggagccggg
    11341 cttgaacgcc ttgccgacct cgctgtgcgc gcggagccag gcggcgcctt ccccgatgcc
    11401 ctggaggacc cggccgccgg gcgggatcgg gccgcccgcc ggggtacgga gctgcttgac
    11461 gacccagttg ccgtccatga ccacatcgac cgtctgcgcc aggaactccg cctggtccgc
    11521 gtaccactgc gcctgccacc cggtgacggg gtcggtccag ctgtcgcccc ggcgcaccgg
    11581 ggtgggggtg gcggcgcccc actccgggcg gaagaccacg atctcgtcgg ggtcgtggca
    11641 ggtggtgttc cgccagggct ggagcgtccg ggtgcggctg gaggcgcggt agtcgttgcc
    11701 gaccccgccg cagcccagca catgaccggc cggccggtgg atgccgtcga ccacccgtac
    11761 cgccccgtcg ggtgcggtga tccgggtctc ggagctgatc tcgtccacgg cggcccggcc
    11821 ctggagcccc tccagcagaa gggcggtcct gccgttgttc ggggtgccga gcagcacgtt
    11881 gttctgcagg tacaggccct gcggcacgcc ttcgaagccg ccgaagtcag cgttgttggg
    11941 gctgtcgatg tcgaactccg agccgttgac cgcgacgagc gccccgctct ccgccgccag
    12001 ttgccgtacg gtctcggagc cctggacgtc cttgccgtgc acggccttca gcgtcacccg
    12061 ggccgacggc gcgaccgtga tcaccctgac ctgccacggg ccccggctcg ggctcccgtc
    12121 ctcggcggtg aagaagatcc ggctcctgcc gaaaccggcg tccgccagcg cctgccgggc
    12181 ctggacggcg tcctcccggc ggtcggcggc gaaccggccg acccggaccc cgtaccccac
    12241 cacccggctg tccgtgtcgg cgctctccgg cacggtgaag acatcgacgc gggcggtgaa
    12301 tccggccgcg tccaggtcct tcgccagccg gtcggcgtcc gcccacgatc cgaaggtctc
    12361 cgtgcccgtc tgcggatggc ggacccagac cgaccaggcg tccgaggcct cgccctgcca
    12421 gtacttgcgg taggtgaccc cgggagccag caggtcggcg ggtctggtcc gggtcggtac
    12481 gtcggcgggg ccgagcggca tccgccccac cggttccgtt ccggccaccg ccccgcccgt
    12541 acgcggcggt tgacccggcg ccgccgcccc gagcagcagc accgaggcga cggcgacggc
    12601 tgcgggcacc cggatccggc ggacgaaccc ggcgggacgg atgaacccgg cgggacgggc
    12661 ggacccggcg ggacgggcgg acccggcagg gcgggcggga agggcggatc cggacggcgg
    12721 tccgggtatc ggcccgggca gcggacggtg cggcacagcg gtctccgttc ggaaaggccc
    12781 tggcagggcg gtcgccccac ttcaccacgc cgccccgccg ggccaccggc acaccccggg
    12841 ccgcccggac cgccggaggg cggccgtgcc taccatcccc tgtgaccgat acgaccgagc
    12901 agcccgcccg ccgcccccgg atattcgccg acctcacccc cctgcgcgcc taccccgact
    12961 accggcggct ctggttcggg aacaccgtgt cctggatcgg gcaggggatg acggccctcg
    13021 ccgtctcgct ccaggtctac gacatcaccg gctccgcgtt ctccgtcggg ctcatcgggt
    13081 tctgctcgct cgtgccgctc gtcgtgttcg ggctctacgg cggggccgtc gcggacaccg
    13141 tcgaccggcg caagctcggc ctgttcagcg ccgccggatc gttcctcctg gccctggtcc
    13201 tggccctggc caccttcgcc ggggccgaga acgtcggcct gctgtacgcc atcgtcgccc
    13261 tccaggccgt ctgcttcgcg ctcaacgccc cggcccgctc ctcgatgatc gcccggctcc
    13321 tgccgcccga acagctgccc gccgccaacg cgctcagctc catgaccacg acgacgggcg
    13381 cgctcgtcgg cccgatgctg ggcgggctga tcgtcggctg gtgggggtac cgcgccgcgt
    13441 acaccgtcga cgccgtcacc ttcaccgcct ccctgtacgc gatgtggcgg ctgccctcga
    13501 tgctgcccga ccggacggcg gagggcgagg cccgcaagcg ggcctccgtg acggacgggc
    13561 tgcgcttcct cggcacccgg cccaacctcc ggatgacctt cttcaccgac ctgtgcgcga
    13621 tggtgctcgc ccacccccgg gcgctcttcc cggtggtcgc cgtcgtctgg tacgggggtg
    13681 acgcccggac caccggcctg ctcgtggccg ccccggcgct cggggcgctg ctcggcgggg
    13741 tcttctccgg ctggctcggc cgcatccgcc gccacggtct cgccgtcctg ctcgccgtcg
    13801 gcagctgggg cgccgccatc gccgtcttcg gcctcacccg ccacctctgg ctggggctgc
    13861 tcttcctggc gctcgccggg tgcgccgaca ccgtctccat ggtcttccgg aacaccatgc
    13921 tccaggcggc ggtcccggac gagatgcgcg gccggctcca aggcgtgttc atcgtcgtgg
    13981 tggcgggcgg gccccggctc ggggacttcc tggccgggtc ggtggccgac ctcacctcac
    14041 cggccgtggc cgtcgtcggg ggcggggcgg cctgcgtggt ggcggtcggg ctgctggccc
    14101 tgaagtggcg gggcttcgcc cggtacgacg cccgcgaccc gcagccgtag ccgccgcccc
    14161 gccgggcggc cgtggcggcc ctaccggacg accgagcggg cgatgcccag ctccaccagg
    14221 tcctgcggcc gcagccggag ctggtcggcg gtggcacccg tctcctccgg cggccgcttc
    14281 aggatggccg ccgcgagttc gggcgcgatg acggagaagt aactgtccgc cgtcacatgg
    14341 gtgttgcccg gcgccgcgag ggccagggca ccgccggagc cgccctcgcc gatcaccagg
    14401 gtggtcaccg gcacccgggc cgccgcgatc gccgcgaagg tgtccgcgat ggccgcgccc
    14461 tggccggccc gttccgcctc ggcgtcgttg gcggcgcccg gggtgtcgac cagggtgagg
    14521 acggggacgc cgagccggtc cgcgagccgg atcgtccggg ccgccgcccg gtatccggcc
    14581 gggcgcgtcg gggtcccgca ctgtgcgacg tacgcgacgg cccgcccgtc cgcccgcagc
    14641 ccgaacccgc tgagcagccc cgggtccgta ccgccggacc ggtccccgtg gagggggagc
    14701 cgttcggcga agtagtcgtc cagatacgcc cgggcccgcg gccgccccac cgcccgggcc
    14761 cgctccaccg cctcccgccc gctccccggc agcccggcgg aggacggtgc ctgggcccgg
    14821 gggagcggcg cggcggcggg tccgtccccg gtaccggcag cctcctcgcc cgcccccaga
    14881 gcccgcagcc acagccccac cgtgcggggc agctccgggc ccgggaccac cgcgtccacc
    14941 tggcccgccg ccgactggcc ctcggcgccg tacgcgtacg ggtcggcgtc cggcggccgg
    15001 acccgggagc cggcgaaccc gatctgggcg cccggcaggg ccagcaccac atccgcgccc
    15061 gcccccacgg tggcccagcc gccgccggtc gtggggtcgc ggaccacggc gatctgcggg
    15121 agccccgccg cccgcagccg ggtggaggcg gcggccaccc gctggagctg ggtgagcgcg
    15181 accatgccct cctgcatccg gctgccaccc gtggcgacga gcgcgaccag cggcagccgg
    15241 cgggccagtg ccaagtcgta cgcggcctcc agccggtcac ccgtcagcag ccccaacgag
    15301 ccgcccagga agccgaactc gaaggcgagc agcacgcact cccggccacc ggcgaccccg
    15361 gtcccgtaca cgaccgactc gtcctcaccg gtccgctccg ccgcccgtgc gcgcgccgcg
    15421 tcgtaccccg cccagccgag cgggccgtcc ggcgggagcg tgcgcggcga cgggggccgg
    15481 tgctcggtga agcccgcccc gccggtgagc agggcgatgg cctcgcgggc ggtggcccgg
    15541 ggcgtcgcac cggacggcgc gccgacggaa gcgtcaccgg actcggggga gccaccagac
    15601 gcaagggagc caccggccag ggggaagcca ccggacgcgg gggcgtcacc ggacatggag
    15661 cgacctcttc atgatcttcc ccaggtcgtt gcggggcagc gcgtccaggt agcgcacggt
    15721 acgcggacgc ttgtgcgggg ccagctgccc ccccaccaga tccgccaact cctcggcggc
    15781 gggcggcgag tcggggtcgg ccgggaccac ccacgccacc acccgctccc cgaggtccgg
    15841 gtccgcctcg ccggtgacgg cggcctcgcg cacgccgggg tggccgagga gcacgttctc
    15901 gatctcgccc gcgccgatct tgtagccgcc gctcttgatg aggtcggtgg ccttgcgccc
    15961 gacgatggtc acgtacccgt ccgtgtccac cgtgccgacg tcgcccgtac ggaaccagcc
    16021 gtcggccgtg tgcgcggcgg cggtggcgtc gggccggttg agatagccgg tgaagaggtt
    16081 cgggccccgg acctggatct ccccgatcgc ctccggcccc tccagcaccg tgccgtcctc
    16141 ctccaccagc cgcagctcca cccccgcgag cggcgggccc accgtgccgg ggcgcggtac
    16201 gccgtccgcc cggatccccg tgttcatcag ggtctccgtc atcccgtacc gctcgatcac
    16261 ccgccgcccg gtcgccgccg cgacgcgctc gtggtcgtgc acggggagcg ccgccgaacc
    16321 ggagaccagc agccgtgccc cggccagcgc cccggccagc gcgtcccgtc cggccgtccc
    16381 cgccggggcg tccagcacct ccgccagccg gtggtacatc gtcggtacgc cgaagagcat
    16441 cgtgcccccc gaccccagct cccgcgccac acccgcggcc gagaacgccc ccaggtgacg
    16501 cagcgaaccg ccccgccgca gcggcccgag gacgcccagg atcagcccgt ggacgtggaa
    16561 cagcggcagc gcgtggacca gcacgtcgtc gccggtccac ccccaggcgt cctccagcgc
    16621 gtccagcgac gcggcgacgg cccgccgggg gagcacggcc cccttgggcg ggccggtggt
    16681 gccggaggtg tagacgatga gggcggggga ctcggggtcg ccttccccgg gcccgggcgc
    16741 gccaccgtcc gccggggcgc cgcctccgcc gtacgcgtac gccgccccgc cccctcggcc
    16801 ttccgcgtac gccgccccgt cccctcggcc ttccgcgtaa gccgccgcgc cgcctccgcc
    16861 ttccgcgtac tccgtcgcgc tcccggtctc cgcccgcgcg tccacggtca cccgccgcac
    16921 cttctccagc gcgggcggca gctcgtcggc ccgtcccgcc aggacggccg tgggctcgct
    16981 gtcggccagg atgtgcgcca actcgcgttc gcccgtgcgg gggttgagcg gcaccaccgg
    17041 cacgtcggcc cgcagggccg ccaccacggc gatcaccgtc tccgccgtcg gagtggccca
    17101 gacggcgacc cggcccgcgt ccgcgatccg ggcggcgagg gcggcggagg ctccggccaa
    17161 ccggccgtag gtcagggaga gatcaccgaa gcggacggcc tcccgggagg ccgtcgggcc
    17221 ggtgggggac tggagcgcgg gaagaaggag ggtcacgccg ggaagcctag gggctcggga
    17281 cggtcccggc cgggtgccgg gtgccgatga ggggagcgtc accatcggcc gacggcggcc
    17341 gttctcccgg cgtcacgagt tgacggtttc ggagccaact cccctgccct gctgcgaaaa
    17401 tgaatttcgc gactgcgatg tgggtgaggc ggcacggtgg agtggacatg cgaggcgtgc
    17461 ggaggtcccg tggcgcaggc cgaaggggtg acaaccgctg cggcggtacg ggtccactct
    17521 cgggaggccg ggcacgacca ggcgagtgtc cggcgtgtga caccgtcggg catcgtgcag
    17581 cgctggcgta ccgaggccga ccgggaacgg cggagagccg aagagcgggc atcgcaggcg
    17641 cggggacgcc ctgagaaggg cacagccgat gaagccacag cggaggcagc cccagcggag
    17701 aaagccccag cggaggaagc cgcgagcgcg accccacgtc ggcccgaagg ctggtacgtg
    17761 cacaccgcgg ccacatccgg ccccacccga ctgccgacaa cgggccgggc ctgggggatc
    17821 ggctgtcttt cgctgttgct tctgatcgtc gtcctcgggc tgttcaccga acctctggag
    17881 ggaggcccgg gcgggaacgg tgacagccct ggtgagagcc gtgaggaatg ccgcgagggg
    17941 tacgaaggtg caggcgatgg aacggtggac tggagaggca tctgcgacct catcgagtag
    18001 cccgccgacc cggtgggcgc cgaccgcacc ggccgcaccg ggcagggccg cagagagcgg
    18061 agacctcacc cgccgcgctg gaggttccgc atccgtgcgt acgcgtacac gcatcccgcc
    18121 agcgccaggt cggacaggag catgaagccg atcgcgtacg agtccttggc gctgtagatc
    18181 gcgcccatca ccagcggcgg tacgaacccg ccgagtccgc ccatcgcgcc cacgatcccc
    18241 gtcacgctgc ccaccttcgc ctgcggggtc acctgcgaga ccagggcgaa gacgctgccg
    18301 ctcgcggtgc cgagcccggc cgccatggcc agcagggcga tggtgccggt cgggttcagg
    18361 ggcggttcga aggcctggac gaccgccatc agggccgcca gcagcagggc gcccgccgtc
    18421 acgagcgccg ggtggacccg gtccgagagc cagccgccga tcggccggaa gacgacggtc
    18481 accagcgcga acccggccgc cttggtgccc gcctcggtcg gtgacatctc gtaccaggtc
    18541 ttcaggtacg tcggcaggta gaccccgaac gccacgatcc cgccgaagcc gatcgcgtac
    18601 agagctgaca gctcccaggt cacccgcagc ctcgccgcgt cgcccagccg gtgggccagc
    18661 gtgtccgtgg ggaccttccg gccggggtgg tcgctgacca ggacggcggc cagcagcgcg
    18721 aagaccacca gcgcccccgc caccacgagg aacggcaggt tgtcgccgtg cttcgcgatg
    18781 cgcggggtga agtagccgga gagcgccacg ccgcccatgc ccatgccgaa cacgcccagc
    18841 gcgaaccccc gtctggcggg cgggaaccac gagttgacca gcgggacgcc gatcgcgaac
    18901 gtcgtgccgc cgagccccag caggaagccg accgcgagca tcgccccgta cgagttcctc
    18961 gccgggatca gcagcagcac cggcacgatc gtcagcgccg acaccagcgg gaacatcagc
    19021 ttcgcgccgt accggtcggt cagcgcgccc accgggatcc ggcccagcga tcccaccagc
    19081 accggcaccg ccaccaggag cgactgctgg aacgagctga gccccagccg gtccttgtag
    19141 tcgccggaca tcggcgcgat caggttccag gcccagaagg tgagggcgaa gccgatcgtg
    19201 gccatgacga ggttccggta cgcggcggcg gacggcgccg cggccgcggc tgccgccggg
    19261 gcggggacgt ccggtggctc ggggggctgc ttgacggcgg agttcacacc gcaagtcaag
    19321 ggcgcggggg agcgcggggc ccgccggagt gcgccgaccg ggcgacggca cccgccctcc
    19381 ccggccgtca cgccccggcg atcacacgct tcccccggcc gtcacgtgct tcccccagcc
    19441 gatatcgccg caagctggga caatcgcggt atggatcggc tggacaggga aatcctcggc
    19501 attctccagg aggacgcccg gatctcgtac cgggatctgg gcgtacgcgt ggggctcagc
    19561 gccaacgcgg cgggcgaccg ggtccgccgg atgcgcaagg acggggtgat ccgtggcttc
    19621 accgtcatcg tcgacccggc cgccgacacc cgttcgggcc tggtcgtctt catcgatgtg
    19681 acgctgcggc tggacacgac gaacgaggag ttcgagcgtt cggtgctgat gctgcccggg
    19741 atcacggagg tggtgcacgt gacgggcggc cacgactatc tgatccgggc cacggcggcc
    19801 gacccggtgg cgctggactc gctgctgcgg cggctcaaaa aggaggcggg cgtggcccac
    19861 tccaccaccc ggatcgccct gcgggcggcg ccgaagcact gacggcgggc tcccgtcccg
    19921 ccccgggagc tcacagcggc gcctgccagg tcaccgtcgt cgaccggccg ccctcctcgt
    19981 cgcggccgtc gtccgccacc agcagccgta cggcgccccg cccgtcggcc agccgcaccg
    20041 tcgcgtccac ctccacctcg atggccgaga ccccgggcct gcggtgcgcg gcggccagcg
    20101 ccttgcggag cgcggccagc agctcgcggc ccgtcgcctc gcccaccagc gcgtccaccg
    20161 cccccgtgaa gtgcaccgac ggcggaaagc ccagcagcgc cgaggcgccc ccggtctccc
    20221 gcagcacccg gccccggaac gtgctcgggg cctcggcggg cggctgctgg agggcgaaga
    20281 tcgcggtgcg gacc
//
