GCF_000576555.1 - 6 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP007145.1 (Hymenobacter swuensis DY53)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	terpene	138,404	159,591
Region 1.2	lanthipeptide-class-i	202,129	232,174
Region 1.3	terpene	1,304,774	1,325,628	Medium	carotenoid	terpene
Region 1.4	RiPP-like	1,543,553	1,554,713
Region 1.5	T3PKS	4,324,984	4,366,150
Region 1.6	terpene-precursor	4,822,197	4,843,168

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	terpene	138,404	159,591
Region 1.2	lanthipeptide-class-i	202,129	232,174
Region 1.3	terpene	1,304,774	1,325,628	Medium	carotenoid	terpene
Region 1.4	RiPP-like	1,543,553	1,554,713
Region 1.5	T3PKS	4,324,984	4,366,150
Region 1.6	terpene-precursor	4,822,197	4,843,168

No secondary metabolite regions were found in these records:: NZ_CP007144.1 (Hymenobacter swuensis DY53); NZ_CP007143.1 (Hymenobacter swuensis DY53); NZ_CP007146.1 (Hymenobacter swuensis DY53)

Compact view

NZ_CP007145.1 - Region 1 - terpene

Download region GenBank file

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Location: 138,404 - 159,591 nt. (total: 21,188 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000592.5	0.40	ribosomal	microviridin B	Microcystis aeruginosa NIES-298
BGC0000641.3	0.36	terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0001787.3	0.36	ribosomal	suicin 3908	Streptococcus suis
BGC0002073.3	0.36	NRPS	dehydroxynocardamine	Corynebacterium propinquum
BGC0000635.3	0.36	terpene	carotenoid	Paracoccus sp. N81106
BGC0000664.5	0.35	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000630.3	0.35	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000537.3	0.35	ribosomal	nisin U	Streptococcus uberis
BGC0000545.5	0.35	ribosomal	ruminococcin A	[Ruminococcus] gnavus E1
BGC0001789.3	0.35	ribosomal	suicin 90-1330	Streptococcus suis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000592.5	0.40	ribosomal	microviridin B	Microcystis aeruginosa NIES-298
BGC0000641.3	0.36	terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0001787.3	0.36	ribosomal	suicin 3908	Streptococcus suis
BGC0002073.3	0.36	NRPS	dehydroxynocardamine	Corynebacterium propinquum
BGC0000635.3	0.36	terpene	carotenoid	Paracoccus sp. N81106
BGC0000664.5	0.35	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000630.3	0.35	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000537.3	0.35	ribosomal	nisin U	Streptococcus uberis
BGC0000545.5	0.35	ribosomal	ruminococcin A	[Ruminococcus] gnavus E1
BGC0001789.3	0.35	ribosomal	suicin 90-1330	Streptococcus suis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
tetraterpene	C40 carotenoid		C40	unknown	unknown

Genes with terpene domains:

HSW_RS02145: Lycopene_cycl

Domain 1 (12 - 382): Lycopene cyclase

Reactions:: C40_carotenoid → C40_carotenoid

Transcription Factor Binding Sites

Binding sites found:

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 18.07 out of 18.16

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.99 out of 26.06

Confidence: medium

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 21.47 out of 21.55

Confidence: strong

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.76 out of 21.55

Confidence: medium

Additional weak hits (9):

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.40 out of 27.78

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.67 out of 26.06

Confidence: weak

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.15 out of 21.55

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 21.71 out of 30.25

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 22.84 out of 30.22

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 21.60 out of 36.54

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 18.52 out of 28.14

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.22 out of 27.78

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 21.33 out of 33.14

Confidence: weak

Terpene

TFBS Finder

Glossary

No acronyms to display

TFBS definitions

Regulator	Description
AbrC3	Antibiotic production activator
ArcA	Repressor of carbon oxidation
MogR	Repressor of flagellar motility genes

NZ_CP007145.1 - Region 2 - lanthipeptide-class-i

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Location: 202,129 - 232,174 nt. (total: 30,046 nt) Show pHMM detection rules used

lanthipeptide-class-i: (((Lant_dehydr_N or Lant_dehydr_C) and cds(LANC_like and not Pkinase)) and not (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Lyases: cyclase dehydratase

HSW_RS02410: Lanthionine synthetase C family protein

smcogs: SMCOG1140: Lanthionine synthetase C family protein

HSW_RS02415: Lanthionine synthetase C family protein

smcogs: SMCOG1140: Lanthionine synthetase C family protein

HSW_RS02445: Lantibiotic dehydratase domain protein

smcogs: SMCOG1155: Lantibiotic dehydratase domain protein

Ligases: synthase

HSW_RS02475: 3-oxoacyl-(acyl carrier protein) synthase III

smcogs: SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002576.2	0.75	ribosomal	mechercharmycin	Thermoactinomyces sp.
BGC0002640.2	0.57	ribosomal	thalassomonasin A, thalassomonasin B	Thalassomonas actiniarum
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122
BGC0000590.5	0.50	ribosomal	microcin N	Escherichia coli
BGC0002005.2	0.50	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0001289.5	0.49	ribosomal	penisin	Paenibacillus ehimensis
BGC0000588.5	0.48	ribosomal	microcin L	Escherichia coli
BGC0002316.2	0.47	ribosomal	cebulantin	Saccharopolyspora cebuensis
BGC0001229.4	0.47	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002698.2	0.46	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002576.2	0.75	ribosomal	mechercharmycin	Thermoactinomyces sp.
BGC0002640.2	0.57	ribosomal	thalassomonasin A, thalassomonasin B	Thalassomonas actiniarum
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122
BGC0000590.5	0.50	ribosomal	microcin N	Escherichia coli
BGC0002005.2	0.50	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0001289.5	0.49	ribosomal	penisin	Paenibacillus ehimensis
BGC0000588.5	0.48	ribosomal	microcin L	Escherichia coli
BGC0002316.2	0.47	ribosomal	cebulantin	Saccharopolyspora cebuensis
BGC0001229.4	0.47	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002698.2	0.46	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for HSW_RS02445

HSW_RS02430

Leader:

MKKKSISLDKSLSLDKETVAKLNEDQ

Core:

LGDVVGGGTTNTCNGTPPAQELEAIPTINSCQACSCN

Core with dehydrations:

LGDVVGGGDhbDhbNDhbCysNGDhbPPAQELEAIPDhbINDhaCysQACysDhaCysN

antiSMASH-DB 4.0 matches for HSW_RS02430

100.0%

NZ_CP007145.1:

Lanthipeptides: HSW_RS02430_lanthipeptide

1

LGDVVGGGTTNTCNGTPPAQELEAIPTINSCQACSCN

37

LGDVVGGGTTNTCNGTPPAQELEAIPTINSCQACSCN

1

LGDVVGGGTTNTCNGTPPAQELEAIPTINSCQACSCN

37

86.8%

NZ_CP007145.1:

Lanthipeptides: HSW_RS02435_lanthipeptide

1

LGDVVGGGTTNTCNGTPPAQELEAIPTINSCQACSCN

37

LGDVVGGGTTNTCN P AQELEAIPTI SCQACSCN

1

LGDVVGGGTTNTCNNVP-AQELEAIPTIGSCQACSCN

36

64.3%

NZ_CP117877.1:

Lanthipeptides: PQ461_RS03050_lanthipeptide

1

LGDVVGGGTTNTCNGTPPAQELE---AIPTINSCQACSCN

37

L +V GGGTTNTCNG PAQ+ E A+ INSCQACSCN

1

LNEVAGGGTTNTCNGNQPAQQFEEAAALIDINSCQACSCN

40

with 2 more sequence matches

18.9%

NZ_CP017599.1:

Lanthipeptides: allorf_3513174_3513389_lanthipeptide

27

TINSCQACSCN

37

TI CQ CSC+

12

TIAVCQGCSCD

22

15.8%

NZ_CP018937.1and 13 others:

NZ_CP018937.1 Lanthipeptides: BUN20_RS17050_lanthipeptideNZ_CP037440.1 Lanthipeptides: IB64_RS01195_lanthipeptideNZ_CP037440.1 Lanthipeptides: IB64_RS01195_lanthipeptideNZ_CP080296.1 Lanthipeptides: K0E65_RS01140_lanthipeptideNZ_CP080296.1 Lanthipeptides: K0E65_RS01140_lanthipeptideNZ_JADKYL010000013.1 Lanthipeptides: ISX59_RS17325_lanthipeptideNZ_JADKYL010000013.1 Lanthipeptides: ISX59_RS17325_lanthipeptideNZ_JADNBK010000016.1 Lanthipeptides: I2C48_RS13935_lanthipeptideNZ_JADNBK010000016.1 Lanthipeptides: I2C48_RS13935_lanthipeptideNZ_JAFKPO010000008.1 Lanthipeptides: K5L50_RS18715_lanthipeptideNZ_JAFKPO010000008.1 Lanthipeptides: K5L50_RS18715_lanthipeptideNZ_QRZH01000013.1 Lanthipeptides: DWW08_RS14950_lanthipeptideNZ_QRZH01000013.1 Lanthipeptides: DWW08_RS14950_lanthipeptide

Lanthipeptides: BUN20_RS17050_lanthipeptide

1

LGDVVGGGTTNTCNGTPPAQELEAI

25

L D+ GG TT+T G P + + +

2

LSDLKGGYTTSTVCGNPTTETVACL

26

HSW_RS02435

Leader:

MKKKSISLDKSLSLDKETVAKLNEDQ

Core:

LGDVVGGGTTNTCNNVPAQELEAIPTIGSCQACSCNGG

Core with dehydrations:

LGDVVGGGDhbDhbNDhbCysNNVPAQELEAIPDhbIGDhaCysQACysDhaCysNGG

antiSMASH-DB 4.0 matches for HSW_RS02435

100.0%

NZ_CP007145.1:

Lanthipeptides: HSW_RS02435_lanthipeptide

1

LGDVVGGGTTNTCNNVPAQELEAIPTIGSCQACSCNGG

38

LGDVVGGGTTNTCNNVPAQELEAIPTIGSCQACSCNGG

1

LGDVVGGGTTNTCNNVPAQELEAIPTIGSCQACSCNGG

38

86.8%

NZ_CP007145.1:

Lanthipeptides: HSW_RS02430_lanthipeptide

1

LGDVVGGGTTNTCNNVP-AQELEAIPTIGSCQACSCN

36

LGDVVGGGTTNTCN P AQELEAIPTI SCQACSCN

1

LGDVVGGGTTNTCNGTPPAQELEAIPTINSCQACSCN

37

64.3%

NZ_CP117877.1:

Lanthipeptides: PQ461_RS03050_lanthipeptide

1

LGDVVGGGTTNTCN-NVPAQELE---AIPTIGSCQACSCNG

37

L +V GGGTTNTCN N PAQ+ E A+ I SCQACSCNG

1

LNEVAGGGTTNTCNGNQPAQQFEEAAALIDINSCQACSCNG

41

with 6 more sequence matches

39.1%

NZ_CP089546.1:

Lanthipeptides: LQ777_RS29915_lanthipeptide

1

LGDVVGGGTTNT--CN----NVPAQELEAIPTIGSCQACSCNGG

38

L +VGG T + CN NV + E E + + SC SCNGG

1

LKALVGGATVKSISCNGGAANVESDEDETLE-VESCCNNSCNGG

43

23.7%

NZ_CM000756.1:

Lanthipeptides: BTHUR0011_RS33055_lanthipeptide

19

QELEAIPTIGSCQACSCNG

37

Q + A T S Q CSC G

2

QVIVASKTFASSQLCSCYG

20

22.8%

NZ_CP018937.1and 13 others:

NZ_CP018937.1 Lanthipeptides: BUN20_RS17050_lanthipeptideNZ_CP037440.1 Lanthipeptides: IB64_RS01195_lanthipeptideNZ_CP037440.1 Lanthipeptides: IB64_RS01195_lanthipeptideNZ_CP080296.1 Lanthipeptides: K0E65_RS01140_lanthipeptideNZ_CP080296.1 Lanthipeptides: K0E65_RS01140_lanthipeptideNZ_JADKYL010000013.1 Lanthipeptides: ISX59_RS17325_lanthipeptideNZ_JADKYL010000013.1 Lanthipeptides: ISX59_RS17325_lanthipeptideNZ_JADNBK010000016.1 Lanthipeptides: I2C48_RS13935_lanthipeptideNZ_JADNBK010000016.1 Lanthipeptides: I2C48_RS13935_lanthipeptideNZ_JAFKPO010000008.1 Lanthipeptides: K5L50_RS18715_lanthipeptideNZ_JAFKPO010000008.1 Lanthipeptides: K5L50_RS18715_lanthipeptideNZ_QRZH01000013.1 Lanthipeptides: DWW08_RS14950_lanthipeptideNZ_QRZH01000013.1 Lanthipeptides: DWW08_RS14950_lanthipeptide

Lanthipeptides: BUN20_RS17050_lanthipeptide

1

LGDVVGGGTTNTCNNVPAQELEAIPTIGSCQ

31

L D+ GG TT+T P E A T G+C

2

LSDLKGGYTTSTVCGNPTTETVACLTRGNCD

32

21.1%

NZ_CP072827.1:

Lanthipeptides: J7W19_RS26345_lanthipeptide

18

AQELEAIPTIGSCQACSCNG

37

AQE+ ++ SC SC G

1

AQEIRGYVSLTSCYQNSCAG

20

18.4%

NZ_CP017599.1:

Lanthipeptides: allorf_3513174_3513389_lanthipeptide

26

TIGSCQACSCN

36

TI CQ CSC+

12

TIAVCQGCSCD

22

15.8%

NZ_KQ948146.1:

Lanthipeptides: allorf_888774_889007_lanthipeptide

18

AQELEAIPTIGSCQACSCNG

37

++ + I ++ SC + SC+G

4

SERMAGIVSLTSCTSHSCHG

23

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 18.25 out of 18.46

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.04 out of 18.57

Confidence: strong

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 22.59 out of 25.88

Confidence: medium

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.86 out of 18.57

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.12 out of 20.97

Confidence: strong

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 17.57 out of 20.97

Confidence: medium

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.86 out of 18.57

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.27 out of 28.19

Confidence: medium

Additional weak hits (15):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.08 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 17.89 out of 26.06

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.36 out of 29.38

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 19.21 out of 29.38

Confidence: weak

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 17.88 out of 21.84

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.36 out of 31.73

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.46 out of 29.65

Confidence: weak

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.63 out of 39.62

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.01 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.22 out of 26.06

Confidence: weak

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 22.41 out of 39.62

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 19.57 out of 28.19

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 19.57 out of 28.19

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 22.29 out of 33.14

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 19.24 out of 28.19

Confidence: weak

Lanthipeptides

RREFinder

TFBS Finder

Core peptide predictions

HSW_RS02430 - Class I

Cleavage pHMM score: -12.70

RODEO score: 17

Monoisotopic mass: 3508.6 Da

Molecular weight: 3510.8 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3528.9 Da N = 1; 3546.9 Da N = 2; 3564.9 Da N = 3

HSW_RS02435 - Class I

Cleavage pHMM score: -12.70

RODEO score: 17

Monoisotopic mass: 3541.6 Da

Molecular weight: 3543.9 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3561.9 Da N = 1; 3579.9 Da N = 2

RRE predictions

: RRE type: Lanthipeptide_LanB_RRE; Location: 157 - 248; Score: 44.0

TFBS definitions

Regulator	Description
CcpA	Catabolite control protein A
PsrA	Oleic acid responsive regulator
RpoN	Regulator of nitrogen assimilation and virulence
ToxT	Regulator of MSHA biosynthesis
ZuR variant 1	Zinc-responsive repressor

NZ_CP007145.1 - Region 3 - terpene

Download region GenBank file

Download region SVG

Location: 1,304,774 - 1,325,628 nt. (total: 20,855 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

HSW_RS07110: dehydrogenase

smcogs: SMCOG1222: dehydrogenase

Lyases: hydratase

HSW_RS07090: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.3	0.63	terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000647.3	0.57	terpene	carotenoid	Rhodobacter sphaeroides
BGC0001456.3	0.49	terpene	isorenieratene	Streptomyces argillaceus
BGC0000633.3	0.47	terpene	carotenoid	Streptomyces avermitilis
BGC0000630.3	0.43	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000635.3	0.42	terpene	carotenoid	Paracoccus sp. N81106
BGC0000664.5	0.42	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.3	0.41	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000637.3	0.40	terpene	carotenoid	Corynebacterium glutamicum
BGC0000634.3	0.40	terpene	carotenoid	Brevundimonas sp. SD212

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.3	0.63	terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000647.3	0.57	terpene	carotenoid	Rhodobacter sphaeroides
BGC0001456.3	0.49	terpene	isorenieratene	Streptomyces argillaceus
BGC0000633.3	0.47	terpene	carotenoid	Streptomyces avermitilis
BGC0000630.3	0.43	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000635.3	0.42	terpene	carotenoid	Paracoccus sp. N81106
BGC0000664.5	0.42	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.3	0.41	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000637.3	0.40	terpene	carotenoid	Corynebacterium glutamicum
BGC0000634.3	0.40	terpene	carotenoid	Brevundimonas sp. SD212

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene		squalene	C30	acyclic	none
triterpene		PSPP	C30	acyclic	PP
triterpene	C30 carotenoid	diapophytoene	C30	acyclic	none
tetraterpene	C40 carotenoid	phytoene	C40	acyclic	none
triterpene		hydroxysqualene	C30	acyclic	OH

Genes with terpene domains:

HSW_RS07115: PT_phytoene_like

Domain 1 (16 - 274): Prenyltransferase; Phytoene synthase like

Subtype: unknown

Reactions:: FPP → squalene; FPP → PSPP; FPP → diapophytoene; GGPP → phytoene; PSPP → hydroxysqualene

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (12):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.75 out of 26.06

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 19.13 out of 28.14

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 19.93 out of 29.38

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.31 out of 30.22

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.43 out of 27.78

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.14 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.66 out of 26.06

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 19.36 out of 29.25

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.61 out of 27.78

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.91 out of 26.06

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 21.63 out of 33.14

Confidence: weak

NrdR

Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 20.39 out of 27.18

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
FPP	Farnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
PP	Diphosphate
PSPP	Presqualene diphosphate

TFBS definitions

Regulator	Description

NZ_CP007145.1 - Region 4 - RiPP-like

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Location: 1,543,553 - 1,554,713 nt. (total: 11,161 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

HSW_RS08115: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

HSW_RS08120: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: formyltransferase

HSW_RS08090: methionyl-tRNA formyltransferase

smcogs: SMCOG1228: methionyl-tRNA formyltransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000866.5	0.48	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000867.3	0.47	other (other)	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0002138.2	0.38	PKS	fuelimycin A, fuelimicin B, fuelimicin C	Streptomyces albireticuli NRRL B-1670
BGC0000218.5	0.38	PKS	doxorubicin	Streptomyces peucetius
BGC0000507.5	0.37	ribosomal	epicidin	Staphylococcus epidermidis
BGC0000384.6	0.36	NRPS	lyngbyatoxin	Lyngbya majuscula
BGC0000217.5	0.36	PKS	daunorubicin	Streptomyces sp.
BGC0000812.3	0.36	other (other)	huperzine A	Shiraia sp. slf14
BGC0000188.5	0.34	other (other)	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001575.4	0.34	NRPS	PZN5, PZN6, PZN7, PZN9, PZN10, PZN11	Ruminococcus sp. 5_1_39BFAA

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000866.5	0.48	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000867.3	0.47	other (other)	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0002138.2	0.38	PKS	fuelimycin A, fuelimicin B, fuelimicin C	Streptomyces albireticuli NRRL B-1670
BGC0000218.5	0.38	PKS	doxorubicin	Streptomyces peucetius
BGC0000507.5	0.37	ribosomal	epicidin	Staphylococcus epidermidis
BGC0000384.6	0.36	NRPS	lyngbyatoxin	Lyngbya majuscula
BGC0000217.5	0.36	PKS	daunorubicin	Streptomyces sp.
BGC0000812.3	0.36	other (other)	huperzine A	Shiraia sp. slf14
BGC0000188.5	0.34	other (other)	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001575.4	0.34	NRPS	PZN5, PZN6, PZN7, PZN9, PZN10, PZN11	Ruminococcus sp. 5_1_39BFAA

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.81 out of 18.57

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.59 out of 30.25

Confidence: medium

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 22.44 out of 26.85

Confidence: medium

Additional weak hits (4):

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.23 out of 39.62

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.89 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 16.83 out of 26.06

Confidence: weak

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.59 out of 18.57

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
ColR	Phenol-responsive regulator
RutR	Regulator of the pyrimidine and purine metabolism
ToxT	Regulator of MSHA biosynthesis

NZ_CP007145.1 - Region 5 - T3PKS

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Location: 4,324,984 - 4,366,150 nt. (total: 41,167 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase

HSW_RS19950: oxidoreductase

smcogs: SMCOG1161: oxidoreductase

HSW_RS20010: aldehyde dehydrogenase

smcogs: SMCOG1017: aldehyde dehydrogenase

Ligases: synthase

HSW_RS19955: chalcone and stilbene synthase domain protein

smcogs: SMCOG1024: chalcone and stilbene synthase domain protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.3	0.54	PKS	2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.3	0.51	PKS	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0002403.2	0.49	PKS	β-Diketones	Hordeum vulgare subsp. vulgare
BGC0002332.2	0.45	PKS	4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A	Candidatus Entotheonella sp.
BGC0001831.3	0.45	PKS	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001077.4	0.44	PKS	6-anteisoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-geranyl-2-methoxyhydroquinone, 6-palmityl-4-O-geranyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-palmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone	Actinoplanes missouriensis 431
BGC0001684.3	0.37	other (other)	N-acyloxyacyl glutamine	Klebsiella variicola
BGC0002007.2	0.36	terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina
BGC0000043.5	0.36	PKS	curacin A	Moorea producens 19L
BGC0001972.4	0.35	other (other)	toxoflavin, fervenulin	Streptomyces hiroshimensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.3	0.54	PKS	2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.3	0.51	PKS	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0002403.2	0.49	PKS	β-Diketones	Hordeum vulgare subsp. vulgare
BGC0002332.2	0.45	PKS	4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A	Candidatus Entotheonella sp.
BGC0001831.3	0.45	PKS	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001077.4	0.44	PKS	6-anteisoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-geranyl-2-methoxyhydroquinone, 6-palmityl-4-O-geranyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-palmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone	Actinoplanes missouriensis 431
BGC0001684.3	0.37	other (other)	N-acyloxyacyl glutamine	Klebsiella variicola
BGC0002007.2	0.36	terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina
BGC0000043.5	0.36	PKS	curacin A	Moorea producens 19L
BGC0001972.4	0.35	other (other)	toxoflavin, fervenulin	Streptomyces hiroshimensis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 21.90 out of 23.79

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 16.08 out of 18.57

Confidence: medium

Additional weak hits (22):

RicR

Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 24.89 out of 32.93

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 19.76 out of 31.73

Confidence: weak

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.42 out of 21.55

Confidence: weak

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.22 out of 21.55

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 17.69 out of 28.14

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.82 out of 27.78

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 19.09 out of 29.38

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.65 out of 29.25

Confidence: weak

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 20.25 out of 30.97

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 17.14 out of 26.06

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 21.43 out of 29.38

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 19.88 out of 30.25

Confidence: weak

CsoR

Description: Copper-responsive repressor
Species: Streptomyces lividans
Score: 22.71 out of 32.38

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 19.30 out of 29.25

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 17.34 out of 26.06

Confidence: weak

MatP

Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.62 out of 25.75

Confidence: weak

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 19.70 out of 25.88

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 19.64 out of 29.38

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 18.93 out of 28.19

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 20.71 out of 29.65

Confidence: weak

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 19.17 out of 24.78

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 19.36 out of 29.25

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
IolR	Regulator of the inositol catabolism
ToxT	Regulator of MSHA biosynthesis

NZ_CP007145.1 - Region 6 - terpene-precursor

Download region GenBank file

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Location: 4,822,197 - 4,843,168 nt. (total: 20,972 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase

HSW_RS21895: aldo/keto reductase family oxidoreductase

smcogs: SMCOG1039: aldo/keto reductase family oxidoreductase

Ligases: synthetase

HSW_RS21920: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001534.3	0.49	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000504.5	0.40	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000486.4	0.40	ribosomal	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0001576.3	0.39	ribosomal	divamide A	Prochloron didemni
BGC0001863.4	0.39	ribosomal, terpene	bacillicn CER074	Bacillus mycoides
BGC0000665.5	0.38	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0001911.3	0.37	terpene	raimonol	Streptomyces anulatus
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001229.4	0.36	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001534.3	0.49	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000504.5	0.40	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000486.4	0.40	ribosomal	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0001576.3	0.39	ribosomal	divamide A	Prochloron didemni
BGC0001863.4	0.39	ribosomal, terpene	bacillicn CER074	Bacillus mycoides
BGC0000665.5	0.38	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0001911.3	0.37	terpene	raimonol	Streptomyces anulatus
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001229.4	0.36	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

HSW_RS21920: PT_FPPS_like

Domain 1 (26 - 321): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (2):

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 19.94 out of 28.14

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.16 out of 27.78

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description