LOCUS       NZ_KI912410            21143 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Actinomadura oligospora ATCC 43269 P696DRAFT_scaffold00001.1, whole
            genome shotgun sequence.
ACCESSION   NZ_KI912410
VERSION     NZ_KI912410.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Actinomadura oligospora ATCC 43269
  ORGANISM  Actinomadura oligospora ATCC 43269
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 1148980)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2014) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            environment                       :: Soil
            investigation_type                :: bacteria_archaea
            project_name :: Actinomadura oligospora ATCC 43269
            sequencing_meth                   :: WGS
            ref_biomaterial                   :: ATCC 43269
            GOLD Stamp ID                     :: Gi22378
            Type Strain                       :: Yes
            Isolation Site                    :: soil, India
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2013-09-10
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000518265.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 02:24:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,332
            CDSs (total)                      :: 8,253
            Genes (coding)                    :: 8,185
            CDSs (with protein)               :: 8,185
            Genes (RNA)                       :: 79
            rRNAs                             :: 7, 2 (5S, 16S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 7 of 68
            Pseudo Genes (incomplete)         :: 65 of 68
            Pseudo Genes (internal stop)      :: 1 of 68
            Pseudo Genes (multiple problems)  :: 5 of 68
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:28:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 777015
            Orig. end                         :: 798158
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KI912410.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 1013217
            Source DNA and organism available from Tim Lilburn at the American
            Type Culture Collection (ATCC) (TLilburn@atcc.org)
            Contacts: Nikos   Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI
            Annotation by JGI
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21143
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21143
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21143
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11143](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11143
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(509..1504)
                     /locus_tag="P696_RS50230"
     CDS             complement(509..1504)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="P696_RS50230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_051468533.1"
                     /transl_table=11
                     /translation="MWERTRERLNDDRHGFGLAAAELYPDVPRVADTTLLTRPGWVPDA
                     PVPLADVHTRWEPLPKPPAVTAPTAGLPEGFNSYADAMAVLARPRVFEDRSSYRLLAVD
                     DLTLTFGPAHYFDAVNVGEAAAHELAAAVPGLPVRTAIGDPTDLTRRPALIAITTLTVT
                     TSGRYVLHWRDPAKVAHAGGLRHVMPVGVFQPLTGRAAELDPWFTMVREYSEELLGASE
                     EYEDDFDQEAWPFHQRMTSALDDGSLRAYYLGLGADPLTLAVDLLTVVVFEDEAFDALF
                     GGGRLVRENAEGHVRLTDLDGTVPEPMQPAGAAALRLAWRHRRALGIRAR"
     gene            complement(1510..2673)
                     /locus_tag="P696_RS57650"
     CDS             complement(1510..2673)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="P696_RS57650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein kinase"
                     /protein_id="WP_281175027.1"
                     /sec_met_domain="Pkinase (E-value: 2.5e-27, bitscore: 91.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRERIGSGGMGTVWRADDAVLHREVAVKELTVPAGGGEELRLRRE
                     ARAVARIDHPGVVRVHDVVDDGGGLWIVMELVPAPSLADVLTARGPLPPGEVAALGAQL
                     AHALAAVHATGVLHRDVKPANVLLRGDGRAVLHQDPERRPSAGEAARLLETGAEPPSRR
                     RAAVVAPVIATVAAVAAGTAAAVLFTHPFDRHHAAAQPRAALSGTISVPPSSSAPPSSP
                     PSTPSSSAPPTSDAPEPSSPPATHTAAAPPSASPSPTRRTETVSVRVDATSGWQSTGLN
                     VKAGQRIGIDFVGGGWTVDHRYFPEVGPQGYDSATDARIYQACKLDPNLRYGVLIGRVG
                     GGSRFVVGTRDSVTAPDPGEFQLRIHDQDHCLVDNGGSLLLKLTYVP"
     gene            complement(2829..3629)
                     /locus_tag="P696_RS0135365"
     CDS             complement(2829..3629)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630104.1"
                     /locus_tag="P696_RS0135365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_026416024.1"
                     /transl_table=11
                     /translation="MLLEDSPGHLPFDGADNVRDLGGNALPGGGATASGRVLRADALTR
                     LSDADVRRLEEFGVRTVIDFRTPMEVDTNGRDRLPDGVLTVHLPVGGGNLGVFYDVIGS
                     GDADRQREAFGDGRLEGLMIDINRTFVRDEAERGRFADAVRLVADAGSVPLLFHCTAGK
                     DRTGWLAAVLLAAVGVDRATIMDDFLRSNHHLRHTTRKILEVIGETRQMAEPELLRPLL
                     EQQPAYLEAAFNEADALFGSFEDFLRDGMGLDDATLAALHKNLT"
     gene            complement(3673..4524)
                     /gene="ddaH"
                     /locus_tag="P696_RS0135370"
     CDS             complement(3673..4524)
                     /EC_number="3.5.3.18"
                     /GO_function="GO:0016403 - dimethylargininase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ddaH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854129.1"
                     /locus_tag="P696_RS0135370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dimethylargininase"
                     /protein_id="WP_051468671.1"
                     /transl_table=11
                     /translation="MEPTQQPSAAPAIPERTAHRRHYLMCRPEHFAVTYAINPWMDPSA
                     GASAELAVTQWEMLRSAYLALGHEVSLIDPLPGMPDMVFAANGALVVGGRAYGARFTFE
                     ERAAEGPAYSAWLRANGFADVRDPEHTNEGEGDFLTLDRLILAGTGFRTDLAAHQEAQE
                     FLGRPVVTLRLVDPRFYHLDTALFPLDGENVAYYPGAFSPGSRAVLERLFPDAVIATEE
                     DAAVLGLNAVSDGRNVVVNAEATGLIRTLAEHGFEPVPVDLTELRKAGGGPKCCTLELR
                     AG"
     gene            complement(4873..6276)
                     /gene="lpdA"
                     /locus_tag="P696_RS0135375"
     CDS             complement(4873..6276)
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013156354.1"
                     /locus_tag="P696_RS0135375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_026416026.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.6e-67, bitscore:
                     221.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHFDVVVLGSGPGGYVAAIRAAQLGLKTAIIEERFWGGVCLNI
                     GCIPSKALLRNAELAHIFTTEQDKYGIKVEGPVSFDYGVAHKRSRQVSEKLVKGVQFLM
                     KKNKITTYEGRGSFSDPNTLQVAGKDGSSETVTFDNCIIAAGAHTRLLPGTRLSERVVT
                     YEEQILSSELPESIVIAGAGAIGVEFAYVLHNYGVKVTIVEFLDRMVPNEDADVSKELN
                     RRYKKLGIEVLTSTRVDAIDDSGAKVKVTITGKDGVQKVLETDKVLQAIGFAPNVEGYG
                     LDKAGVKVTDRGAIDVDGRCRTSAGHIYAIGDVTAKLMLAHAAEAMGIVAAETIANAET
                     MEIDFAMVPRATYCQPQVASFGYTEQQARDLGYDVKVAKFPYSANGKALGMGEGDGFVK
                     LVSDAKYGELLGGHLIGPEVTELLPELTLAQQWDLTVHEVARNIHAHPTLSEAVKEAVH
                     GLAGHMINL"
     misc_feature    complement(6387..6406)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.63"
                     /tool="antismash"
     gene            6432..6851
                     /locus_tag="P696_RS0135380"
     CDS             6432..6851
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="P696_RS0135380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_026416027.1"
                     /transl_table=11
                     /translation="MRIPKPVNAALDWAEQHFGALAAVVALVLAAAAALALPRLVGLPL
                     AGFVLGTAIGGFVVYARMSRRLARARRDNDDLLRENGALRHRNTILSSGVITRESQTTQ
                     ALLMIPEDEDETGGSSNGGRDPQRTVQLPELPDEL"
     misc_feature    complement(6881..6895)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    complement(6882..6895)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            7180..8574
                     /locus_tag="P696_RS0135385"
     CDS             7180..8574
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017613244.1"
                     /locus_tag="P696_RS0135385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_245627933.1"
                     /transl_table=11
                     /translation="MTEQQTDQQQRSLATGAARNLATTTKTVPQMQGISSRWLLKLLPW
                     VQCAGGAYRVNRRLAYTIGDGRVEFIQTGADVQVIPLELGELPVLRGYEDEDVLGELAG
                     RFEQREYEPGDVIVTAGQNADTVVLVVHGKLEKVGEGEYGGETVLATLADGSFFGADVL
                     EGGEHDWEFSVRAVTPATVLTLPVARFRELMDRAQGLREHVDSFRDRPEAAKSADGEAA
                     IALAAGHEGEPVLPGTFVDYEPEPREYELSVAQTVLRVHTRVADLYSQPMDQTEQQLRL
                     TIEALRERQEHELVNNRDFGLLHNADLRQRVPTRSGPPTPDDMDELLTLVWKEPAFFLA
                     HPRTIAAFGRECSRQGVYPDPVEVQGHHIPAWRGVPIFPCNKIPISKTRTSSVMLMRTG
                     ESAQGVVGLHRTGLKDEVQPGVVARFMQIDEKAIMSYLVSAYYSAAVLVPDALAVLESV
                     EIGVAQ"
     gene            8571..9956
                     /locus_tag="P696_RS0135390"
     CDS             8571..9956
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017619263.1"
                     /locus_tag="P696_RS0135390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_026416029.1"
                     /transl_table=11
                     /translation="MTTPAGADPQQLSLSTGAARNLATTTKSAPMMQGITPRYLLRLLP
                     WVEVGGGTYRVNRRLAHTVGDGIVEFVNTGAAINVIPAELAEIPQLAGVDEALLTDTAG
                     RFVQREYEPGDLIVEPGGPVDRVVLVAHGKVERVGRGEYGAEAVLDLLADGRYFGASAL
                     LPAPGEWEHAYRAVTPTSVLVLSNEQIGELLGRYPELRERLASFAGAPRPATNAKGEAE
                     IELMSGHEGEPVLTGTFADYEPSPRQYELSVAQTLLRVHTRVADLYSDPMDQVEQQMRL
                     TVEALRERQEDELVNNRDFGLLHNADLKQRIQTRSGPPTPEAMDDLLSRRRGTKFYLAH
                     PRTIAAFGRECTRQGVYSGSVERFGRQVMAWRGVPIFPCDKIRISDRGTSAVLAMRIGE
                     DDQGVVGLHQTGLADELQPGLSARFTGIDDRAVLSYLVSAYFSAAVLVPDALGVLENVE
                     VNR"
     gene            10001..11143
                     /locus_tag="P696_RS50240"
     CDS             10001..11143
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073756.1"
                     /locus_tag="P696_RS50240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_245627934.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.3e-64, bitscore:
                     212.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRRRTVPTRAAATVPAAPPATEATPSPAEPPAEPPAARRARGPA
                     RPAGASSAETLTWARDLIDPGLRDTVGSMPGSMARIASYHFGWEDAEGRPARADGGKVL
                     RPALTLLCAEAAGGTAQAALPAAVAVELVHNFSLLHDDVMDGDLTRRHRPTAWNVFGAG
                     PAILAGDALLARALELLAGAGEGVVMLSRAVLELVEGQSSDMSFERRSDVDLAECVQMA
                     DRKTGALIGASCGLGALYGGAPAARAARLTAFGHRLGLAFQLVDDLLGIWGDPATTGKA
                     AHSDLRSRKKSLPVVAALTSGTAAAGELAALYHQDRPLGEAERARAAELVEAAGGRDWA
                     RTRALELLEEALAELDAADPAGPAAEHLRGLAGLVTTRDH"
     gene            complement(11239..11820)
                     /locus_tag="P696_RS0135400"
     CDS             complement(11239..11820)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592850.1"
                     /locus_tag="P696_RS0135400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_026416030.1"
                     /transl_table=11
                     /translation="MARAGLTVDRIVQAAAEMADEQGVENVSVSALARRFGVRDASLYS
                     HIRSLADLRRRVALKAGDEQAGRIAEAVAGRAGRDALVAFANAYRDYAREHPGRYAAMQ
                     IPVDPEAARLVAEGRAEGSRGVEVTAAMMRAYDLPDPDLTDAVRLLRSTFHGFISLEAN
                     GAFGHPRDVQASWDKALEALHQLLTAWPRT"
     misc_feature    11784..11798
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.12"
                     /tool="antismash"
     misc_feature    complement(11811..11830)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.76"
                     /tool="antismash"
     gene            complement(11853..12803)
                     /locus_tag="P696_RS0135405"
     CDS             complement(11853..12803)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629871.1"
                     /locus_tag="P696_RS0135405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_245627935.1"
                     /transl_table=11
                     /translation="MENPSPGDSTTSRESTPPAGNATPDPNTTPRAGAAPGAASGSAPG
                     ADVTADGGAAALGRVARGVLYPARHVEVVETARHDPSPEAARYVELYWHVRWRVDEPHD
                     SKVLSYPSVHLVFEDPEPMIYGVVRDLFVRRLEGEGQVLGVKFHPGCFRPFAGGPVSAF
                     TDRTVPAAEVFGPEVVDVGRRVMAGRETADLAAPAERFLLDRLPEPDPTAHEVAGMVER
                     ITARPDLFRVDQAAEALHVSTRTLQRLFAEYVGVTPKWVMRRARLQEAATRADAGDTVD
                     WAALAADLGYFDQAHLVRDFTATVGVPPARYARSV"
     misc_feature    complement(12818..12834)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.98"
                     /tool="antismash"
     gene            12870..13448
                     /locus_tag="P696_RS0135410"
     CDS             12870..13448
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629872.1"
                     /locus_tag="P696_RS0135410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_026416032.1"
                     /transl_table=11
                     /translation="MKDLHTHMKECAAEAARVARGVPAGHWDDTTTCADFDLRTLVNHW
                     VLYTSHGLEHRARREALPDELTGRDFTADPDWAVAYAAQLDRAVAAWADPEVWEGDIDL
                     GEMTVPAKDIAGMVIKEMAVHGWDVAMSTGQTFEVSDEAAVFVLSVVEANAEIYRQYDG
                     FADPVEIDASAPVFARALALSGRDPHWTR"
     misc_feature    13488..13497
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     misc_feature    13494..13509
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.17"
                     /tool="antismash"
     misc_feature    complement(13495..13508)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            13524..13754
                     /locus_tag="P696_RS0135415"
     CDS             13524..13754
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="P696_RS0135415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157430105.1"
                     /transl_table=11
                     /translation="MTTEHVPFLCPRGHRLGPGRVIVGWSPCGCPPCLERGRGLRGHRT
                     YLCLTCKDEHVTTMCYLPPHLPAPDAAHRWP"
     gene            complement(13815..16220)
                     /locus_tag="P696_RS0135420"
     CDS             complement(13815..16220)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014717.4"
                     /locus_tag="P696_RS0135420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_026416034.1"
                     /transl_table=11
                     /translation="MSALGRIVRSGVARKRVQTLVLTLTTMLAVTASVLAAGLVVASRA
                     PFDHAFAKQHGAHLTARFDGSRATPEQLAATAHAPGVTATAGPFPVLTLRPSFGEGGGG
                     PDPLPMTIAGRPAPDGPVDDVDLVDGRWATTRGEIVVDADGPPFPVGHKVTFSQAAGHP
                     TLTIVGRARSVGRSADAWVAPAQLTALTTRAPDQQMLYRFRHAATDAQMSAGRAAVTAA
                     APRGSLTGAGSYLTIRHKAQRETATFVPFIVAFGLLALVMSVLTIGVVVNAAVAAATHR
                     IGVLKSLGFTPSQVVTGYVGKALIPAAIGTGLGVVFGNLLAIPAMRQEGNAYQTGSRTV
                     APWIDVAVAAAALAAVAVTALVPALRAGRLRAAEAIAIGRAPRPGRGRTARRLLGRLPL
                     ARPVSLGLAAPFARPARSVAMGLALMLGTAAVAFGTGLALSLNGIQNGLNQDEAGAVTV
                     HVMGRPGMQAGPDGAPEAPAPGQRPRNGPAPTPEPADPAAIARTIEAQPGTRRYFSVSE
                     ARIGVAGMTSAASLTAYTGDASWGAFQIVSGRWFHGPGEAVAPSALLKATGTRVGGTIT
                     LTNAGRTARVRIVGEIMMVRDDGMDVLTDTASTAPLGIGFDPGMTEFHIDVKDGTDAGA
                     YTRSLDRALQGVGGAADRNTAHISPTVVAMDTLAGMLTVLLVVVAGLGVLNTVVLDTRE
                     RVHDLGVLKALGMAPRQVIGMIITTVGLVGLCFAAAGIPLGMALHAAVVPEMGKAAGTG
                     IPSADLNVFDLPLLAVLLLGGVLIAVAGALLPAGWAARTRTSTALRTE"
     gene            complement(16217..16885)
                     /locus_tag="P696_RS0135425"
     CDS             complement(16217..16885)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631888.1"
                     /locus_tag="P696_RS0135425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_026416035.1"
                     /transl_table=11
                     /translation="MIEIRAVTKSYDDGGPALADLNLTVAEGEALAVLGPSGSGKSTLL
                     NLVAGLDRPTEGTVTVAGTRVDDLSETALARYRRRKVGMVFQFFNLLDDLTVIDNVLLP
                     AQLSRMSRRAARDRAEELLGKLGVLQHARAFPGRLSGGERQRVAVARALMNRPPLLLAD
                     EPTGALDTASAADVRDLLTGLNADGQTMLLVTHDTALADACATRTIELTDGRITRMATR
                     "
     gene            17084..18469
                     /locus_tag="P696_RS50245"
     CDS             17084..18469
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="P696_RS50245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine kinase"
                     /protein_id="WP_064744201.1"
                     /transl_table=11
                     /translation="MSRTVLADRRAALWNALWRVTPDPPSRTSRWAVMADAVLAVLLAV
                     GALGVVMDVSDDGPHPFPPGDQYPPDPSDPPDVPDEPDAPDVPGAPLAPPPPPEPHYGP
                     GVHVPGMRGLDPAHTTLHGLSVWWHIALALLIALPIAVRRRYPLGALWTVSVAAVLFHK
                     GVYLNPTFTFAALVIAAYSAVVYSPHQRLAIGTAVVDVLAVVLFRHSLVPQMNPSLLGF
                     LLLIPVGLGANAIHTWQQRVRALEARQEEATRRAVERERSRIAQELHDVVTHNVSVMVV
                     QAGAARMVLRDEPDRAEAAMRAVESGGRAAMTELRHVMNLLTMDGEPEEADLAPRPGLA
                     QVPALAERVRATGVKVDLIVSGEPSDLPEGMDLAAYRVVQEALTNTLKHAAGARVGIVV
                     AHTPGELTVEVTDTGGGATSHSGNGRGLLGLRERVAVFGGVLEHGPTPSGGYRVHATFP
                     AAR"
     gene            18466..19140
                     /locus_tag="P696_RS0135435"
     CDS             18466..19140
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545858.1"
                     /locus_tag="P696_RS0135435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_026416036.1"
                     /transl_table=11
                     /translation="MTAPRVVIADDQALVRTGFGMILTAAGIDVVAEVEDGARAVEAVR
                     ALRPDVVLMDIQMPGLDGLTATRRILSAGTPSRVIMLTTFDLDRYVYAALAAGASGFLL
                     KDVSPEHLAAAVRLVRTGDALLAPSITRRLVERFATRADAAEPATALHRDLTPLTTREL
                     EVLRLLARGRTNAELAAHLHLSEATVKTHVARILSKLDLRDRAQAIIVAYETGLITPGH
                     SG"
     gene            19162..19563
                     /locus_tag="P696_RS0135440"
     CDS             19162..19563
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620739.1"
                     /locus_tag="P696_RS0135440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_026416037.1"
                     /transl_table=11
                     /translation="MRIDLVALVVEEYDPAIEFFVGVLGFELVEDSPALTNDGRAKRWV
                     VVRPAGGGTGLLLARADGERQEAAVGDQVAGRVGFFLNVDDFDAKYEQMVAAGVRFVTE
                     PRDEPYGRVAVFLDIAGNRWDLLGKADGS"
     gene            complement(19589..20566)
                     /locus_tag="P696_RS0135445"
     CDS             complement(19589..20566)
                     /NRPS_PKS="Domain: PKS_ER (24-322). E-value: 6.2e-50.
                     Score: 162.0. Matches aSDomain:
                     nrpspksdomains_P696_RS0135445_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592424.1"
                     /locus_tag="P696_RS0135445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="quinone oxidoreductase"
                     /protein_id="WP_026416038.1"
                     /sec_met_domain="ADH_N (E-value: 5.9e-13, bitscore: 44.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2e-25, bitscore:
                     85.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSTAIVIREQGGPEVMRPEQVDVPSEVGAGEALVEVAYAGVNFI
                     DIYQRNGRYTMETPFVPGNEGSGRVVAVGDGVTAVEVGDRVAWEGVAGSYARHVVAPAA
                     RLLPVADDVDDAQAAALPLQGLTAHYLTTESHPIAAGETVLVHAGAGGTGLAVTQVAKI
                     LGATVITTVSTEEKAKISREAGADHVLVGYDGFDARVRDLTGGLGVHAVYDGVGQATFD
                     GSLASLRRRGTFVLFGGSSGAVPPVDPMRLNAAGSVKFTRPTLWDFVADPAELRARYGD
                     VLGWASQGRLSVRVHAEYPLEDAPQAHRDLAGRGTVGKLLLRTG"
     aSDomain        complement(19601..20494)
                     /ASF="ER domain putatively catalyzing 2R-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_P696_RS0135445_PKS_ER.1"
                     /evalue="6.20E-50"
                     /label="P696_RS0135445_PKS_ER.1"
                     /locus_tag="P696_RS0135445"
                     /protein_end="322"
                     /protein_start="24"
                     /score="162.0"
                     /tool="antismash"
                     /translation="PSEVGAGEALVEVAYAGVNFIDIYQRNGRYTMETPFVPGNEGSGR
                     VVAVGDGVTAVEVGDRVAWEGVAGSYARHVVAPAARLLPVADDVDDAQAAALPLQGLTA
                     HYLTTESHPIAAGETVLVHAGAGGTGLAVTQVAKILGATVITTVSTEEKAKISREAGAD
                     HVLVGYDGFDARVRDLTGGLGVHAVYDGVGQATFDGSLASLRRRGTFVLFGGSSGAVPP
                     VDPMRLNAAGSVKFTRPTLWDFVADPAELRARYGDVLGWASQGRLSVRVHAEYPLEDAP
                     QAHRDLAGRGTVGKLLL"
     CDS_motif       complement(19907..19942)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_P696_RS0135445_0003"
                     /evalue="5.10E-01"
                     /label="PKSI-ER_m5"
                     /locus_tag="P696_RS0135445"
                     /protein_end="220"
                     /protein_start="208"
                     /score="3.4"
                     /tool="antismash"
                     /translation="VHAVYDGVGQAT"
     CDS_motif       complement(20030..20074)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_P696_RS0135445_0002"
                     /evalue="3.80E-04"
                     /label="PKSI-ER_m6"
                     /locus_tag="P696_RS0135445"
                     /protein_end="179"
                     /protein_start="164"
                     /score="13.3"
                     /tool="antismash"
                     /translation="GATVITTVSTEEKAK"
     CDS_motif       complement(20084..20146)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_P696_RS0135445_0001"
                     /evalue="6.80E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="P696_RS0135445"
                     /protein_end="161"
                     /protein_start="140"
                     /score="21.8"
                     /tool="antismash"
                     /translation="GETVLVHAGAGGTGLAVTQVA"
     misc_feature    complement(20770..20784)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    21083..21098
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.79"
                     /tool="antismash"
ORIGIN
        1 cgggcgcgcg gacggcgggc agaacgacgg ccagaaccag gtgtcgctga tgtccgcgcc
       61 gctcgccgtg cacatcgcgg acccggccga gcggtacgcg gccgtccggg acgacatgga
      121 gcgggccaag cggaggttcg tcggatcgtc cggggcgtgg gtgcgggacc tgaccgggat
      181 ggtgcccgcg ccgctcgccg ggcccgtcgc gcggctcgcg ctgagcgtcc tgcccgggct
      241 gcccgtccgg ccgctgaacc tgatcgtgtc gaacgtgccg ggcccgcagt tcccgctgta
      301 cctgtgcggc gcgcgggtgc tcgcgtacta cccgctctcg gtggtcagcg ggatcagcgg
      361 cggcctgaac atcaccgtgt tctcctacga cgggacggtg cacgtgggcc ttgtgtcctg
      421 ccgcgacctc gtcccgaacc cgggcgagct gatcgaccac ctcgccgacg cgatggccga
      481 gctcagggcg ctcgccgagg gctgaggctc agcgcgcccg gatgccgagg gcccgccggt
      541 gccgccatgc cagccgcagc gcggcggctc cggcgggctg catcggctcg ggcacggtcc
      601 cgtcgaggtc cgtgagccgg acgtgtccct ccgcgttctc ccggacgagg cgtccgccgc
      661 cgaacagggc gtcgaacgcc tcgtcctcga agacgaccac ggtcagcagg tcgacggcga
      721 gcgtcagcgg gtcggcgccg agaccgaggt agtacgcgcg cagggaaccg tcgtcgaggg
      781 cgctggtcat ccgctggtgg aacggccagg cctcctggtc gaagtcgtcc tcgtactcct
      841 cggacgcgcc gagcagctcc tccgagtact cgcggaccat cgtgaaccac gggtccagct
      901 cggcggcgcg tccggtcagc ggctggaaca cgccgaccgg catcacgtgg cgcagcccgc
      961 ccgcgtgcgc gaccttcgcc ggatcgcgcc agtgcaggac gtaccgtccg gacgtcgtga
     1021 cggtcagcgt cgtgatcgcg atcagcgccg gacgccgcgt caggtcggtc gggtcgccga
     1081 tcgccgtccg caccggaagc ccggggacgg cggcggcgag ctcgtgcgcg gcggcctcgc
     1141 ccacattgac cgcgtcgaag tagtgggcgg gcccgaaggt caaagtcagg tcgtccacgg
     1201 cgaggaggcg gtaggacgac ctgtcctcga acacgcgcgg gcgcgcgagg acggccatgg
     1261 cgtccgcgta actgttgaag ccctccggca gacccgcagt gggcgctgta acagcgggag
     1321 gcttagggag aggctcccag cgcgtgtgga cgtccgccag aggcaccggc gcgtccggaa
     1381 cccacccagg acgcgtcagg agggtcgtgt ccgcgacgcg cggcacgtcc gggtacagct
     1441 ccgccgccgc gagcccgaag ccgtgccggt cgtcgttcag gcgctcccgc gtccgctccc
     1501 acatgcccct cacggtacat acgtgagctt cagcaacagg cttccgccgt tgtcgaccag
     1561 gcagtggtcc tggtcgtgga tgcggagctg gaactcgccc gggtccggcg cggtgaccga
     1621 gtcgcgcgtc ccgaccacga accggctccc gccgccgacc cggccgatca ggacgccgta
     1681 gcgcaggttc gggtcgagct tgcaggcctg gtagatccgc gcgtcggtgg cggagtcgta
     1741 gccctgcggc ccgacctcgg ggaagtagcg gtggtcgacg gtccagccgc cgcccacgaa
     1801 gtcgatcccg atccgctgcc ccgccttcac gttcaggccg gtgctctgcc agccgctcgt
     1861 ggcgtccacg cgcaccgaga ccgtctccgt ccggcgcgtg ggcgaggggc tcgcgctcgg
     1921 cggggccgcc gccgtgtgcg tcgcgggtgg gctggacggt tccggcgcgt cggacgtcgg
     1981 cggcgcggac gacgacggcg tcgacggcgg cgaggacggc ggtgcgctgc tcgacggcgg
     2041 gacgctgatc gtgccgctca gcgccgcgcg cggctgggcg gcggcatggt gccggtcgaa
     2101 cgggtgcgtg aacaggacgg ccgcggccgt cccggcggcc accgcggcca cggtcgcgat
     2161 caccggcgcg acgacggccg cccggcgtcg gctcggcggc tcggcgcccg tctccagcag
     2221 ccgcgcggcc tccccggcgg acggacggcg ctctggatcc tggtgcagca ccgcccgccc
     2281 gtccccgcgc agcagcacgt tcgcgggttt gacgtcccgg tgcagcaccc cggtcgcgtg
     2341 cacggcggcg agcgcgtgcg ccagctgcgc gccgagcgcc gccacctcgc ccggcgggag
     2401 ggggccgcgc gccgtcagga cgtccgcgag cgacggcgcg ggcaccagct ccatgacgat
     2461 ccacagcccg cccccgtcgt ccacgacgtc gtgcacccgg accacgcccg gatgatcgat
     2521 gcgcgcgacc gcccgcgcct cccggcgcag ccgcagctcc tcgccgccgc ccgccggaac
     2581 ggtcagctcc ttgaccgcca cctcacggtg caggacggcg tcgtccgccc gccacaccgt
     2641 gcccatgccg ccgctgccga tccgctcccg cagccggtag cggcccgcga ccgtccgccc
     2701 ggcgcgcccc cgtgatcccg cgcaccgccc aaacgcaccg cctcctccgt acggctggcc
     2761 gtgcgccgaa tatcgaccga gacgggcgag ccgtcaacag ccttcggggg cgggatcccc
     2821 ggcggccctc aggtgaggtt cttgtggagg gcggcgagag tggcgtcgtc caggcccatg
     2881 ccgtcgcgga ggaagtcctc gaacgagccg aacagggcgt ccgcctcgtt gaaggcggcc
     2941 tccaggtagg cgggctgctg ctccagcagc gggcgcagca gttccggctc ggccatctgg
     3001 cgcgtctcgc cgatcacctc gaggatcttc cgggtggtgt gccgcaggtg gtggttggac
     3061 cgcaggaagt cgtccatgat cgtggcacgg tccacgccga ccgcggccag caggacggcg
     3121 gccagccagc cggtgcggtc cttgcccgcc gtgcagtgga acagcagcgg caccgacccg
     3181 gcgtccgcga cgagccggac cgcgtccgcg aaccggccgc gctcggcctc gtcccggacg
     3241 aacgtccggt tgatgtcgat catgaggccc tcgaggcggc cgtccccgaa cgcctcgcgc
     3301 tgccggtcgg cgtcgccgct gccgatcacg tcgtagaaca cgccgaggtt gccgccaccg
     3361 accggcaggt ggacggtcag aacgccgtcc gggagccggt cgcggccgtt ggtgtccacc
     3421 tccatcgggg tccggaagtc gatgaccgtc cggaccccga actcctccag ccggcgcacg
     3481 tcggcgtcgc tcagccgggt cagcgcgtcc gcgcgcagga cccggccgga cgccgtcgcg
     3541 ccgcccccgg gcagggcgtt cccacccagg tcgcgcacgt tgtccgcgcc gtcgaacggg
     3601 aggtggccgg gggagtcctc gagcagcatg accccatcgt cccggacgtc gggcgaatcg
     3661 ggcgaaccgg ggtcagccgg cccgcagttc gagcgtgcag cacttcgggc cgccgcccgc
     3721 cttccgcagc tcggtcaggt ccaccgggac cggctcgaag ccgtgctcgg cgagcgtcct
     3781 gatcagcccg gtggcctccg cgttcaccac cacgttccgg ccgtcgctca ccgcgttcag
     3841 gccgagcacc gccgcgtcct cctccgtcgc gatcaccgcg tcggggaaca gccgctccag
     3901 caccgcgcgg ctgccggggg agaacgcgcc cgggtagtac gcgacgttct cgccgtccag
     3961 cgggaacagc gccgtgtcca ggtggtagaa ccgcgggtcc accagccgca gcgtcaccac
     4021 cgggcggccc aggaactcct gcgcctcctg gtgagccgcg aggtccgtcc ggaacccggt
     4081 cccggcgagg atcagccggt ccagcgtgag gaagtcgccc tcgccctcgt tggtgtgctc
     4141 ggggtcacgc acgtccgcga acccgttcgc gcgcagccag gcgctgtacg ccgggccctc
     4201 ggcggcccgc tcctcgaagg tgaaccgcgc cccgtaggcc cgtccgccca ccacgagcgc
     4261 gccgttggcc gcgaacacca tgtccggcat tcccggcagc gggtcgatca ggctcacctc
     4321 gtgcccgagc gccaggtagg ccgagcgcag catctcccac tgcgtcacgg ccagctccgc
     4381 gctcgccccc gccgacgggt ccatccacgg gttgatcgca taggtgaccg cgaagtgctc
     4441 cggacggcac atcaggtagt gccgccggtg cgccgtccgc tccgggatcg ccggtgcggc
     4501 ggacggctgc tgtgtcggct ccatcgccgg ggtgacggtc atgacgcgcg ctcctgctca
     4561 gtccacgggc catcagatga ccgaaagcct aggaacgccg cgccccgcac ccaaccccac
     4621 gaaattgcgc tgaccaggag tttcgttgcg tctatccccc tccccccggc gattcgttgc
     4681 gcccacccca ccaagcccgg cactacgggc gcagagcgcc cttcgcgccg tgcgcgcgcg
     4741 accatcgtcc gcgcgcgtga gatgtccccc cgcgggggtg aggggccgtc gtccggaggg
     4801 ggccggggac gcacgcggcc gtccccgcgg ggcggggacg gccggtgtga gcgccgtggt
     4861 ggggcctggt cgctagaggt tgatcatgtg gccggcgagg ccgtggacgg cctccttgac
     4921 ggcctcgctc agcgtggggt gggcgtggat gttgcgggcg acctcgtgga cggtgaggtc
     4981 ccactgctgg gccagggtca gctcgggcag gagctcggtg acctcggggc cgatcaggtg
     5041 gccgccgagc agctcgccgt acttggcgtc cgagacgagc ttgacgaagc cgtcgccctc
     5101 gcccatgccg agcgccttgc cgttggcgct gtaggggaac ttggcgacct tcacgtcgta
     5161 gccgaggtcg cgggcctgct gctcggtgta gccgaaggag gcgacctgcg gctggcagta
     5221 ggtggcgcgc gggaccatgg cgaagtcgat ctccatggtc tcggcgttcg cgatggtctc
     5281 ggcggcgacg atgcccatgg cctcggcggc gtgcgcgagc atcagcttgg cggtgacgtc
     5341 gccgatcgcg tagatgtgcc cggcggacgt gcggcagcgg ccgtccacgt cgatcgcgcc
     5401 gcggtcggtg accttgacgc cggccttgtc gaggccgtag ccctcgacgt tcggggcgaa
     5461 gccgatggcc tgcaggacct tgtcggtctc caggaccttc tggacgccgt ccttgccggt
     5521 gatcgtgacc ttgaccttcg cgccggagtc gtcgatcgcg tcgacccggg tggaggtgag
     5581 gacctcgatg ccgagcttct tgtagcggcg gttgagctcc ttggagacgt cggcgtcctc
     5641 gttcgggacc atccggtcga ggaactcgac gatcgtgacc ttcacgccgt agttgtgcag
     5701 cacgtaggcg aactcgacgc cgatggcgcc cgcgcccgcg atcacgatgc tctcgggcag
     5761 ctcggacgag aggatctgct cctcgtaggt caccacgcgc tcggagagcc tggtgcccgg
     5821 cagcaggcgg gtgtgcgcgc ccgccgcgat gatgcagttg tcgaaggtga ccgtctcgga
     5881 cgagccgtcc ttcccggcga cctgaagggt gttcgggtcg gagaacgagc cacggccctc
     5941 gtaggtcgtg atcttgttct tcttcatcag gaactggacg cccttgacga gcttctccga
     6001 gacctgacgg ctgcgcttgt gggccacccc gtagtcgaac gacaccgggc cctcgacctt
     6061 gatcccgtac ttgtcctgct cggtggtgaa gatgtgggcc agctcggcgt tgcggagcag
     6121 cgccttggag gggatgcagc cgatgttgag gcatacgccg ccccagaacc gctcctcgat
     6181 gatggccgtc ttcaggccga gctgggccgc gcggatcgcg gcgacatagc cacccgggcc
     6241 ggaacccagg accacgacgt caaagtgttc gctcattcct ccgacgatat tgcgcgcgga
     6301 gcagtgctcg catcttatgc gccatccccg gagaggcgtt cgtcacactg tgtcagggtc
     6361 gggcctggtt gcgggacggt aacgttcaag ggacgcccgt ccccgtcacg gctcaggagg
     6421 agtagtccaa ggtgcggatc cccaagcctg tcaacgcggc cctcgactgg gcggagcagc
     6481 acttcggcgc gctcgcggcg gtggtggctc tcgtgctggc ggccgcggcg gcgctcgcgc
     6541 tgccgcgcct ggtgggcctg cccctggcgg gcttcgtcct cggcacggcg atcggcggat
     6601 tcgtcgtcta cgcgcgcatg tccaggcggc tagcccgggc gcgcagggac aacgacgacc
     6661 tgcttcggga gaacggcgcg ctgcggcacc gcaacacgat cctgtcgagc ggcgtgatca
     6721 cccgcgagtc gcagacgacc caggcgctcc tgatgatccc ggaggacgag gacgagaccg
     6781 gggggtcgtc gaacggcgga cgcgacccgc agcgcaccgt ccagctcccc gaacttcctg
     6841 acgagttgta aggcccttcc ccgtccggcg cgacccggcg atcaccgagc gtgatcgccg
     6901 ggtcgccgtc gttgatcgac ttcgtccacc ggcggcggga cggcggcggg tgggcggttc
     6961 ccgggggccg gtccccgcgg cggcagggca agggtcgcct aaggattgcg ttttgtgtta
     7021 cccaaggtga ggtaatactt ccgttgtgtc agtgtgatta cgctgggtaa tgtcactgct
     7081 gcacgcggtc catccccccg gcgacgcgtc ggtcaggagg accgcgcgcg atagcgcgcc
     7141 attcggcggc cgacaagtac cggaacggtg gtgtccagcg tgaccgaaca gcagaccgac
     7201 caacagcagc ggagtctggc gaccggcgcg gcgcggaacc tcgcgaccac gaccaagacc
     7261 gtgccccaga tgcagggcat ctcctcgcgc tggttgctca agctgctccc gtgggtgcag
     7321 tgcgcgggcg gcgcgtaccg ggtcaaccgg cggctggcgt acaccatcgg ggacggccgg
     7381 gtcgagttca tccagaccgg cgccgacgtc caggtcatcc ccctcgagct cggcgagctg
     7441 ccggtgctgc ggggctacga ggacgaggac gtcctcggcg agctcgcggg ccggttcgag
     7501 cagcgcgagt acgagccggg tgacgtgatc gtcacggcgg ggcagaacgc cgacaccgtc
     7561 gtgctcgtcg tgcacggcaa gctcgagaag gtcggcgagg gcgagtacgg cggcgagacc
     7621 gtcctcgcca ccctcgccga cgggtccttc ttcggcgcgg acgtcctgga gggcggggag
     7681 cacgactggg agttctcggt ccgggccgtg acccccgcga ccgtcctgac cctcccggtg
     7741 gcccggttcc gcgagctgat ggaccgcgcg cagggcctgc gcgagcacgt cgactccttc
     7801 cgcgaccgtc cggaggcggc gaagagcgcc gacggcgagg ccgcgatcgc gctcgccgcc
     7861 ggacacgagg gcgagcccgt cctgcccggc acgttcgtcg actacgagcc cgagccgcgc
     7921 gagtacgagc tgagcgtcgc gcagaccgtc ctgcgcgtgc acacccgcgt cgcggacctg
     7981 tacagccagc ccatggacca gaccgagcag cagctgcggc tgaccatcga ggcgctgcgc
     8041 gagcggcagg agcacgagct ggtcaacaac cgcgacttcg ggctgctgca caacgccgac
     8101 ctgcggcagc gcgtgcccac ccggtccggc ccgcccaccc cggacgacat ggacgagctc
     8161 ctcaccctcg tgtggaagga gcccgcgttc ttcctcgcgc acccgcgcac gatcgccgcg
     8221 ttcggccgcg agtgcagccg gcagggcgtc tacccggacc cggtcgaggt ccagggccac
     8281 cacatcccgg cgtggcgcgg ggtgccgatc ttcccgtgca acaagatccc gatcagcaag
     8341 acccggacca gctcggtcat gctcatgcgg accggcgagt ccgcgcaggg cgtcgtcggc
     8401 ctgcaccgca ccggcctcaa ggacgaggtc cagcccggcg tggtggcccg cttcatgcag
     8461 atcgacgaga aggccatcat gtcctacctg gtcagcgcct actactccgc cgccgtgctg
     8521 gtgccggacg cgctcgccgt gctggagagc gtggagatcg gggtggcgca gtgaccactc
     8581 ccgcgggcgc ggacccgcag cagctgagcc tgtcgaccgg ggccgcgcgg aacctggcga
     8641 cgaccaccaa gtccgcgccc atgatgcagg gcatcacgcc gcgctacctg ctgcggctgc
     8701 tgccctgggt ggaggtcggg ggcggcacct accgggtgaa ccgccgcctc gcccacaccg
     8761 tcggggacgg gatcgtcgag ttcgtcaaca ccggcgccgc gatcaacgtg atccccgccg
     8821 agctggccga gatcccgcag ctcgcgggcg tcgacgaagc gctcctgacc gacaccgccg
     8881 gacggttcgt ccagcgcgag tacgagccgg gcgacctgat cgtcgagccc ggcggcccgg
     8941 tcgaccgggt ggtgctcgtc gcgcacggca aggtcgagcg ggtcggccgg ggcgagtacg
     9001 gcgcggaggc cgtgctcgac ctgctcgccg acggccgcta cttcggcgcc agcgcgctgc
     9061 tgcccgcgcc gggcgagtgg gagcacgcct accgcgcggt caccccgacg agcgtcctgg
     9121 tcctgtcgaa cgagcagatc ggcgagctgc tcggccgcta cccggagctg cgcgagcggc
     9181 tggcgtcgtt cgcgggcgcg ccccgtccgg cgaccaacgc caagggcgag gccgagatcg
     9241 agctgatgtc cgggcacgag ggcgagcccg tcctgaccgg cacgttcgcc gactacgagc
     9301 cgtccccgcg gcagtacgag ctgagcgtcg cgcagacact gctgcgcgtc cacacccggg
     9361 tggccgacct gtacagcgac ccgatggacc aggtcgagca gcagatgcgg ctgaccgtcg
     9421 aggcgttgcg cgagcggcag gaggacgagc tggtcaacaa ccgcgacttc gggctgctgc
     9481 acaacgcgga cctgaagcag cggatccaga cccggtccgg cccgccgacc cccgaggcga
     9541 tggacgacct gctgagccgc cgccgcggga cgaagttcta cctggcgcac ccgcgcacga
     9601 tcgccgcgtt cggccgcgag tgcacccggc agggcgtcta ctcggggtcg gtcgagcggt
     9661 tcgggcggca ggtgatggcc tggcgcggcg tgccgatctt cccctgcgac aagatccgga
     9721 tcagcgaccg cggcaccagc gccgtgctcg cgatgcggat cggcgaggac gaccagggcg
     9781 tcgtcggcct gcaccagacc ggcctcgccg acgagctgca gcccggcctg tcggcccggt
     9841 tcaccgggat cgacgaccgc gccgtcctgt cctacctcgt gtccgcctac ttctccgccg
     9901 ccgtcctggt cccggacgcg ctcggtgttc tggagaacgt cgaagtcaac cggtgacccg
     9961 cacgtccccc catccccctc acccccacca ggaggccgta gtgccccgcc gacgcactgt
    10021 gccgacgcgc gccgcagcga ccgttcccgc ggccccgccg gcgaccgagg cgacaccgag
    10081 tcccgccgag ccgcccgccg agccgcccgc ggcccggcgg gcgcgcggcc cggcccgtcc
    10141 ggcgggcgcg tcctcggcgg agacgctcac ctgggcccgg gacctgatcg atcccgggct
    10201 tcgggacacg gtcgggagca tgccgggctc gatggcccgc atcgcgtcct accacttcgg
    10261 ctgggaggac gccgagggcc gtccggcccg cgcggacgga gggaaggtgc tgcggcccgc
    10321 gctcacgctg ctgtgcgccg aggcggcggg cggcacggcg caggccgcgc tgcccgccgc
    10381 ggtcgcggtg gagctggtgc acaacttctc gctgctgcac gacgacgtga tggacggcga
    10441 cctcacccgg cggcaccgtc cgaccgcgtg gaacgtgttc ggcgccggtc cggcgatcct
    10501 cgccggggac gcgctgctcg cgcgcgcgct cgagctgctc gccggtgcgg gcgagggcgt
    10561 cgtgatgctg tcgcgggcgg tgctggagct ggtcgaaggg cagtccagcg acatgtcgtt
    10621 cgagcgccgc tcggacgtgg acctggccga gtgcgtccag atggccgacc ggaagacggg
    10681 cgcgctgatc ggggcgtcct gcgggctggg cgcgctgtac ggcggcgccc cggcggcgcg
    10741 ggccgcccgg ctcaccgcgt tcgggcaccg cctcgggctg gccttccagc tcgtggacga
    10801 cctgctcggc atctggggcg acccggccac caccggcaag gccgcgcact ccgacctgcg
    10861 cagccgcaag aagtccctgc cggtggtcgc ggccctgacg tccggcacgg cggcggccgg
    10921 ggagctcgcc gccctctacc accaggaccg tccgctcggg gaggccgaac gcgcccgggc
    10981 cgccgagctc gtcgaggccg cgggcggacg cgactgggcc cgcacccgcg cgctcgaact
    11041 gctcgaggag gccctggccg agctcgacgc ggccgatccg gcgggcccgg ccgccgagca
    11101 cctccgcggc ctcgccgggc tggtcaccac gcgcgaccac tgacccgccg accgcccgcg
    11161 cggcgttgac cacctgcgcg gcgcagacca cctgtcaagc ccggcacgac ggcaagccat
    11221 gccgtggtgc cgggcctttc aggtcctcgg ccaggcggtg agcagctggt gcagggcctc
    11281 cagggccttg tcccaggacg cctggacgtc gcgcggatgc ccgaacgcgc cgttcgcctc
    11341 cagggagatg aacccgtgga aggtgctgcg cagcagccgg acggcatcgg tcaggtcggg
    11401 gtcgggcagg tcgtaggcgc gcatcatcgc ggcggtgacc tcgacgccgc gcgagccctc
    11461 cgcccggccc tcggccacga gcctggccgc ctccgggtcg acggggatct gcatggcggc
    11521 gtagcggccg gggtgctcgc gggcgtagtc gcggtaggcg ttggcgaacg cgaccagggc
    11581 gtcgcgtccg gcgcgtccgg ccacggcctc ggcgatgcgt ccggcctgct cgtcgcccgc
    11641 cttgagggcg acgcggcggc gcaggtcggc caggctcctg atgtgcgagt acaggctcgc
    11701 gtcccggacg ccgaaccggc gcgcgagcgc cgagaccgac acgttctcca ccccctgctc
    11761 gtcggccatc tccgccgccg cctggacgat cctgtccacc gtcagccccg ctcgggccat
    11821 gcgtccccca ctcctggttc ggatcggact gtctacacgc tgcgggcgta gcgggcgggc
    11881 gggacgccga ccgtggcggt gaagtcgcgc accaggtggg cctggtcgaa atagcccagg
    11941 tcggcggcca gcgccgccca gtcgacggtg tcgcccgcgt ccgcgcgggt cgcggcctcc
    12001 tggagccggg cgcggcgcat cacccacttg ggggtgacgc cgacgtactc ggcgaacagc
    12061 cgctgcagcg tgcgggtgga gacgtgcagg gcctcggcgg cctggtcgac gcggaacagg
    12121 tccggacgcg cggtgatccg ctcgaccatc cccgcgacct cgtgcgccgt cgggtcgggc
    12181 tcgggcagcc ggtcgagcag gaacctctcg gccggggcgg cgaggtcggc ggtctcgcgg
    12241 cccgccatga cccgccgtcc gacgtcgacg acctcagggc cgaagacctc ggcggccggg
    12301 acggtgcggt cggtgaacgc gctcaccggt ccgcccgcga acggccggaa gcagcccggg
    12361 tggaacttca ccccgagcac ctggccctcg ccctccagcc gccgcacgaa caggtcgcgg
    12421 acgaccccgt agatcatcgg ctccgggtcc tcgaacacca ggtggacgct cggatacgac
    12481 aggaccttgc tgtcgtgcgg ctcgtccaca cgccaccgca cgtgccagta cagctcgacg
    12541 taccgggcgg cctcggggga cgggtcgtgc cgcgcggtct cgaccacctc cacatgccgc
    12601 gccggataca gaaccccccg cgcgactcgt ccgagggccg ccgcgccgcc gtcggccgtg
    12661 acgtccgcgc caggtgctga gccggacgcc gcgcccggtg ccgcgcccgc gcggggcgtc
    12721 gtgttcgggt cgggcgttgc gttcccggcg gggggtgtgc tctcgcggga tgtcgtgctg
    12781 tcgccgggtg acgggttctc cacggggacc agcctagctg tcgcgaatct ccaagaaccg
    12841 ggaggtcgcg ggcccttagt gtggtcgtca tgaaggacct gcacactcac atgaaggaat
    12901 gcgccgccga ggccgcgcgc gtcgcccggg gcgtcccggc gggccactgg gacgacacga
    12961 cgacgtgcgc cgacttcgac ctgcggacgc tggtgaacca ctgggtcctc tacacctcgc
    13021 acggcctgga gcaccgggcg cggcgggagg ccctgccgga cgagctgacc gggcgcgact
    13081 tcaccgccga cccggactgg gccgtcgcct acgccgcgca gctcgaccgg gccgtcgccg
    13141 cctgggccga cccggaggtc tgggagggcg acatcgacct cggcgagatg accgtcccgg
    13201 cgaaggacat cgcggggatg gtgatcaagg agatggccgt ccacggatgg gacgtcgcca
    13261 tgtccacggg gcagacgttc gaggtctcgg acgaggccgc cgtgttcgtc ctgtcggtgg
    13321 tggaggcgaa cgccgagatc taccgccagt acgacgggtt cgccgacccg gtcgagatcg
    13381 acgcgtccgc gccggtgttc gcgcgggcgc tggcgctgtc cggccgcgac ccccactgga
    13441 cgcggtgacc cgacgcctcg cggcccggcg ttatgccggg ccgctggtgt ttttcgattg
    13501 tatgttcgat tagagtgctc ggtgtgacga ccgagcatgt gcccttcctg tgcccgcgcg
    13561 ggcaccgcct ggggcccggc cgggtgatcg tcggctggtc cccgtgcggc tgcccgccgt
    13621 gcctggaacg ggggcggggg ctgcgcggcc atcgcaccta cctgtgcctg acctgcaagg
    13681 acgagcacgt gaccaccatg tgctacctgc cgccccacct tcccgcgccg gacgccgccc
    13741 accgctggcc ctgacccgtc cggcacgccg tcgtccggtg cgcgggtgtc tggtgtgcgg
    13801 gggttcgggg tgggtcattc ggtgcggagg gccgtggacg tgcgggtccg ggcggcccag
    13861 cccgcgggga gcagcgcgcc cgcgaccgcg atcaggacgc cgccgagcag caggacggcc
    13921 agcagcggca ggtcgaagac gttcaggtcg gcggagggga tgcccgtccc ggcggccttg
    13981 cccatctccg ggacgacggc cgcgtggagc gccatcccga gggggatccc ggccgccgcg
    14041 aagcacagcc cgaccagccc gaccgttgtg atgatcatgc cgatgacctg ccgtggagcc
    14101 atcccgagcg ccttgaggac gcccaggtcg tgcacccgtt cgcgggtgtc gagcacgacc
    14161 gtgttgagca cgccgagccc ggccaccacg accagcagga cggtcagcat ccccgcgagc
    14221 gtgtccatgg cgacgaccgt ggggctgatg tgggcggtgt tccggtcggc ggctccgccg
    14281 acgccttgca gggcacggtc cagcgacctg gtgtaggcgc ccgcgtcggt gccgtccttg
    14341 acgtcgatgt ggaactcggt cattccgggg tcgaagccga tgccgagcgg tgccgtggac
    14401 gcggtgtcgg tcagcacgtc catgccgtcg tcgcgcacca tcatgatctc gccgacgatc
    14461 cggacccggg cggtccgtcc ggcgttggtc agggtgatcg tgccgccgac ccgtgtcccg
    14521 gtcgccttca gcagcgcgga cggcgcgacc gcctcgccgg ggccgtggaa ccagcgcccg
    14581 gagacgatct ggaaggcgcc ccacgacgcg tccccggtgt aggcggtcag ggaggcggcg
    14641 ctggtcatcc cggcgacgcc gatccgcgcc tcggacacgg agaagtaccg gcgggtgccc
    14701 ggctgcgcct cgatcgtccg ggcgatggcg gcggggtcgg cgggctcggg ggtgggcgcc
    14761 ggcccgttcc ggggccgctg accgggcgcg ggggcctcgg gtgctccgtc cgggccggct
    14821 tgcatgccgg ggcggcccat gacgtggacc gtgacggctc cggcctcgtc ctggttcagg
    14881 ccgttctgga tgccgttcag ggagagggcg aggcccgttc cgaacgcgac cgccgccgtg
    14941 ccgagcatca gcgccaggcc catcgccacc gaccgggccg gacgggcgaa cggcgcggcg
    15001 aggccgaggc tcaccggacg cgccagcggc agtcttccga gcaggcggcg ggccgtccgg
    15061 ccccggccgg gacgcggcgc gcgcccgatc gcgatcgcct ccgccgcccg gagccgtccg
    15121 gcgcggagcg cggggaccag ggccgtgacc gcgacggcgg cgagcgcggc ggcggccacc
    15181 gcgacgtcga tccacggcgc gaccgtccgg gacccggtct ggtaggcgtt gccctcctgg
    15241 cgcatcgccg ggatcgccag caggttgccg aacacgacgc cgaggcccgt cccgatcgcg
    15301 gccgggatca gcgccttgcc cacgtacccg gtcacgacct gcgagggcgt gaagccgagc
    15361 gacttcagca cgccgatccg gtgcgtcgcg gcggcgacgg cggcgttcac cacgaccccg
    15421 atcgtcagca ccgacatcac gagcgcgagc agcccgaacg ccacgatgaa cggcacgaac
    15481 gtcgcggtct cccgctgcgc cttgtgccgg atcgtcaggt aggagcccgc gccggtcagc
    15541 gagccgcgcg gggcggcggc ggtgaccgcg gcgcggccgg cggacatctg ggcgtcggtc
    15601 gccgcgtgcc ggaaccggta gagcatctgc tggtcggggg cccgcgtggt cagcgcggtg
    15661 agctgcgcgg gggcgaccca cgcgtcggcg ctgcggccga ccgaccgggc ccgtccgacg
    15721 atggtgaggg tcggatggcc cgccgcctgc gagaacgtga ccttgtggcc gaccgggaac
    15781 ggcgggccgt cggcgtcgac gacgatctcg ccccgtgtcg tcgcccaccg gccgtcgacg
    15841 aggtcgacgt cgtcgacggg gccgtccggc gcgggacgtc cggcgatggt catcgggagc
    15901 gggtccgggc cgccgccgcc ctcaccgaag gacggccgca gcgtcagcac cgggaacggc
    15961 ccggccgtgg ccgtgacgcc gggcgcgtgc gcggtcgcgg cgagctgctc cggcgtggcg
    16021 cggctcccgt cgaaccgggc ggtcaggtgc gcgccgtgct gcttggcgaa ggcgtggtcg
    16081 aacggcgccc gggacgccac gaccagcccc gccgccagca cggacgcggt caccgccagc
    16141 atcgtcgtca gcgtcaggac gagggtctgc acccgcttgc gcgccacgcc cgagcggacg
    16201 atccgtccga gcgcgctcat cgggtcgcca tccgggtgat ccggccgtcg gtcagctcga
    16261 tcgtccgggt cgcgcacgcg tcggcgagcg cggtgtcgtg cgtgaccagc agcatcgtct
    16321 ggccgtcggc gttcaggccg gtcagcaggt cgcggacgtc ggcggcggac gcggtgtcca
    16381 gcgcgccggt cggctcgtcg gcgaggagca gcggcgggcg gttcatcagc gcgcgggcga
    16441 ccgcgacgcg ctgccgctcg ccgcccgaca gccgtccggg gaacgcccgc gcgtgctgga
    16501 ggacgccgag cttcccgagc agctcctcgg cgcggtcccg ggccgcgcgc cgcgacatgc
    16561 gcgagagctg cgcgggcagc agcacgttgt cgatgacggt caggtcgtcc aggaggttga
    16621 agaactggaa caccatcccg accttcctgc ggcggtacct cgcgagcgcg gtctcggaca
    16681 ggtcgtccac gcgcgtcccg gcgaccgtga ccgtcccctc ggtgggacgg tccaggcccg
    16741 cgaccaggtt gagcagcgtc gacttcccgc tgccggacgg cccgagcacg gcgagcgcct
    16801 cgccctccgc cacggtcagg ttcaggtcgg cgagggcggg cccgccgtcg tcataggact
    16861 tcgtcaccgc gcggatctcg atcacggcgt ctcctcatcg tctggggtcg cccagacggt
    16921 aggaagcgtg gggcggacgg cgcgtcggcc gcgctgatgg gatcgggtcg gccgcgcggg
    16981 cgattcccgg tccgggtcat cctcgcgatg tacgccgcgc ggcgggtccg tcgcgttccc
    17041 ggggaggatg tgccggtttc tggttgcttg ccatagtgag ccggtgagca gaaccgtcct
    17101 cgcggaccgc cgggccgccc tctggaacgc gctctggcgc gtgacgccgg acccgccgtc
    17161 gcgcacgtcc cgctgggccg tcatggcgga cgcggtgctg gccgtcctgc tggccgtggg
    17221 cgcgctgggc gtcgtgatgg acgtgtccga cgatggtccg cacccgtttc ctccggggga
    17281 ccagtacccc ccggacccga gcgacccgcc ggacgtcccg gacgaacctg acgcgccgga
    17341 tgttccgggt gcaccgctcg caccaccccc accgcccgaa ccgcactacg ggccgggcgt
    17401 gcacgtcccg ggcatgcgcg ggctggaccc cgcgcacacc acgctccatg gcctgtcggt
    17461 gtggtggcac atcgcgctgg cgctcctgat cgccctgccg atcgccgtcc gccgccggta
    17521 cccgctcggc gcgctgtgga cggtgtccgt cgcggcggtg ctgttccaca agggcgtcta
    17581 cctgaatccg accttcacgt tcgcggccct ggtcatcgcc gcctacagcg ccgtcgtcta
    17641 cagcccgcac cagcggctcg cgatcgggac ggccgtcgtg gacgtcctgg cggtcgtcct
    17701 cttccgccac tcgctggtgc cccagatgaa cccgagcctg ctcggcttcc tgctgctgat
    17761 cccggtcggg ctcggcgcga acgcgatcca cacctggcag cagcgcgtcc gcgcgctgga
    17821 ggcgaggcag gaggaggcca cccgccgcgc cgtcgaacgg gaacgatcgc gcatcgccca
    17881 ggaactgcac gacgtcgtga cccacaatgt gagcgtgatg gtggttcagg cgggtgcggc
    17941 ccgcatggtc ctgcgggacg aaccggaccg cgccgaggcg gcgatgcggg ccgtcgagtc
    18001 cggcgggcgc gcggcgatga ccgagctccg gcacgtcatg aacctgctga ccatggacgg
    18061 cgagcccgag gaggccgatc tcgcgccgcg tcccggcctc gcccaggtcc cggccctcgc
    18121 cgagcgcgtc cgcgcgaccg gcgtgaaggt cgacctgatc gtcagtggcg aaccgtccga
    18181 cctgcccgaa gggatggacc tggccgcgta ccgggtcgtc caggaggcgc tcaccaacac
    18241 gctcaagcac gccgccggag cccgcgtcgg catcgtcgtc gcccacactc cgggcgagct
    18301 gaccgtcgag gtcaccgaca ccggcggcgg cgccacgtcc cactccggga acggacgcgg
    18361 cctgctcggc ctgcgcgaac gcgtcgccgt cttcggcgga gtcctggagc acgggcccac
    18421 gccgtccggc ggctaccgcg tccacgccac gttcccggcg gcgcgatgac cgcgccgcgc
    18481 gtggtgatcg ccgacgacca ggccctcgtc cgcaccggct tcggcatgat cctcaccgcc
    18541 gccgggatcg acgtggtcgc cgaggtcgag gacggcgccc gcgcggtcga ggccgtccgc
    18601 gcgctgcggc ccgacgtcgt cctgatggac atccagatgc ccggactgga cggcctgacc
    18661 gccacccgcc gcatcctgtc ggcgggcacc ccgtcccggg tgatcatgct gacgaccttc
    18721 gacctcgacc gctacgtcta cgccgccctc gccgcgggcg ccagcggctt cctcctgaag
    18781 gacgtctcgc ccgagcacct cgccgccgcc gtccggctcg tccgcaccgg ggacgccctc
    18841 ctcgcgccgt ccatcacccg ccgcctggtc gaacgcttcg ccacccgcgc cgacgccgcc
    18901 gagcccgcca ccgccctgca ccgcgacctg accccgctga ccacccgcga actcgaggtc
    18961 ctccgcctcc tcgcccgtgg ccgcaccaac gccgaactcg ccgcccacct gcacctgagc
    19021 gaggccaccg tgaagaccca cgtcgcccgc atcctgtcca aactcgacct ccgcgaccgg
    19081 gcccaggcca tcatcgtcgc ctacgagacc ggcctcatca ccccaggcca ttcggggtga
    19141 gtgtggatct acgatcggcg gatgcggatt gacctggtgg cgctggtggt cgaggagtac
    19201 gacccggcga tcgagttctt tgtcggagta ctcgggttcg agctggtgga ggactctccg
    19261 gccctcacga acgacgggcg ggccaagcgg tgggtggtgg tgcgtccggc gggaggcggg
    19321 acggggttgc tgctcgcgcg ggcggacggg gagcggcagg aggccgcagt tggtgaccag
    19381 gtcgcgggac gggtcgggtt cttcctgaac gtggacgact tcgacgcgaa gtacgagcag
    19441 atggtcgcgg cgggagtgcg gttcgtcacc gagccccggg acgagccgta cggacgggtc
    19501 gcggtgttcc tcgacatcgc cgggaaccgc tgggacctgc tcgggaaggc ggacggatcc
    19561 tgagatccgt ccgccgcccc cgagggcgtc agccggtgcg gagcaggagc ttgccgacgg
    19621 tgccgcgccc ggcgaggtcg cggtgggcct ggggggcgtc ctcgagcggg tactcggcgt
    19681 ggacgcgcac agaaaggcgg ccctgggacg cccagccgag gacgtcgccg tagcgggcgc
    19741 ggagctcggc cgggtcggcg acgaagtccc agagggtggg acgggtgaac ttgaccgatc
    19801 ccgccgcgtt gaggcgcatc gggtcgaccg gcgggacggc gccgctcgac ccgccgaaca
    19861 ggacgaacgt gccacggcgg cgcagggacg cgagggagcc gtcgaaggtg gcctgcccga
    19921 ccccgtcgta gacggcgtgg acgccgaggc cgccggtcag gtcgcggacg cgggcgtcga
    19981 agccgtcgta gccgaccagg acgtggtcgg ccccggcctc gcgggagatc ttcgccttct
    20041 cctccgtgga gaccgtggtg atgacggtcg cgccgaggat cttcgcgacc tgggtcaccg
    20101 cgaggccggt gccgcccgcg cccgcgtgga ccaggacggt ctccccggcg gcgatggggt
    20161 gcgactcggt cgtgaggtag tgcgcggtca ggccctggag ggggagcgcg gcggcctgcg
    20221 cgtcgtccac gtcgtccgcg acgggcagca ggcgcgcggc cggggcgacg acgtgccgcg
    20281 cgtacgaccc tgccacgccc tcccaggcga cgcggtcgcc gacctcgacc gctgtgacgc
    20341 cgtcgccgac cgcgacgacg cgtccggagc cctcgttgcc cggcacgaac ggcgtctcca
    20401 tcgtgtagcg gccgttgcgc tggtagatgt cgatgaagtt gaccccggcg taggcgacct
    20461 cgacgagcgc ctcacccgcc ccgacctcgg acggcacgtc cacctgttcc ggccgcatca
    20521 cctcgggccc gccctgctcc cggatcacga tcgccgtcga ctgcataggt gactccttgt
    20581 cctcggtgtt cccctcaccg gccaacccgc ggtggctctc aatcattccg atcgggaaag
    20641 tcggcgtgcc acggtctcac gggtgtccgc cgggagcgcg tctccggcgt cctggaggcg
    20701 ggggaggagt tcgggttcga gggtgagggc gcggaagacc aggccgatgc tcacctcgtg
    20761 ggacggacgg tcgacgacgg tgatctcgtc gcccttcgcg atgtcgccgg gctcgacgac
    20821 gcggaagtac gtgccgggca gggcgcgggc ggtgaaggtc ttgatccatc cgggctcgtc
    20881 catccagccc gcgaacgtcc ggcacgggat gcgcggcgcg gacacctcca gcaggacgtc
    20941 gcggccgacg cgccagcgct cgccgatgag cgctgcgttg acgtccacac cggacgtggt
    21001 gaggttctcg ccgaacgagc cgctggggat gtcgcggccg agttcggcgc cccacgcgtc
    21061 caggtcctcg cgcgcgtacg cgtagacggc ctggtcgtcg ccgccgtggt ggcgcaggtc
    21121 gtagacgcgg tcgcccgcga gtc
//
