LOCUS       NZ_JADG01000023        14176 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Actinomadura oligospora ATCC 43269 P696DRAFT_scaffold00020.20_C,
            whole genome shotgun sequence.
ACCESSION   NZ_JADG01000023
VERSION     NZ_JADG01000023.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Actinomadura oligospora ATCC 43269
  ORGANISM  Actinomadura oligospora ATCC 43269
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 108354)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2014) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            environment                       :: Soil
            investigation_type                :: bacteria_archaea
            project_name :: Actinomadura oligospora ATCC 43269
            sequencing_meth                   :: WGS
            ref_biomaterial                   :: ATCC 43269
            GOLD Stamp ID                     :: Gi22378
            Type Strain                       :: Yes
            Isolation Site                    :: soil, India
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2013-09-10
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000518265.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 02:24:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,332
            CDSs (total)                      :: 8,253
            Genes (coding)                    :: 8,185
            CDSs (with protein)               :: 8,185
            Genes (RNA)                       :: 79
            rRNAs                             :: 7, 2 (5S, 16S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 7 of 68
            Pseudo Genes (incomplete)         :: 65 of 68
            Pseudo Genes (internal stop)      :: 1 of 68
            Pseudo Genes (multiple problems)  :: 5 of 68
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:28:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14176
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADG01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..14176
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..14176
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14176
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1059:4176](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1060..4176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(528..546)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.72"
                     /tool="antismash"
     CDS             674..886
                     /gene="allorf_000674_000886"
                     /locus_tag="allorf_000674_000886"
                     /protein_id="allorf_000674_000886"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAVVGARGRVGGGFLGGMRCGLVRTRRWSRTGIAGSAPRTRLSRL
                     LTRRRRSRGTGCLLTWGFLRWRGHC"
     CDS_motif       674..781
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAVVGARGRVGGGFLGGMRCGLVRTRRWSRTGIAGS"
                     /locus_tag="allorf_000674_000886_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       782..886
                     /prepeptide="core"
                     /locus_tag="allorf_000674_000886_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.00"
                     /molecular_weight="4004.7"
                     /monoisotopic_mass="4002.3"
                     /core_sequence="APRTRLSRLLTRRRRSRGTGCLLTWGFLRWRGHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAVVGARGRVGGGFLGGMRCGLVRTRRWSRTGIAGS"
                     /leader_location="[673:781](+)"
                     /alternative_weights="4022.7"
                     /alternative_weights="4040.7"
                     /alternative_weights="4058.7"
                     /alternative_weights="4076.8"
     gene            1060..4176
                     /locus_tag="P696_RS0129720"
     CDS             1060..4176
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024964.4"
                     /locus_tag="P696_RS0129720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_170026609.1"
                     /sec_met_domain="DUF4135 (E-value: 7.1e-69, bitscore:
                     225.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.2e-14, bitscore:
                     44.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSLGEPERGLAVWARYPVLARQVVDVLDGWVGARRAFARDLVDD
                     LPALREAFGPELGDLRQVMFGSAETHRGGRTVALVRFAGATVVYKPRGLGIDLAFDRLL
                     GWFNERGPRFALRRLRLLDRGDHGWCEFVQAAPTSVGDAPALLWRTGALLALMHAVGGF
                     DLHADNVISDGADPVVIDLEALFHTGLTQPLVRRARLGDPAADRLATSVLRTGLLPGPL
                     VMPDVFTERPFGVDISPFGPAERRTLIPIPKVDDPGTDRMRVGRGYRTVPAPPGRARNE
                     DGTPLDPRPHRDALHDGHRFAYRLLAEAGPALVTSRDGRDGPLAGCGDVSIRLVQLSTF
                     LYMRLLLESWRPEAMRLAEERERGFARLDAGWPGVPERARLIGVERDALWRGEVPVFEL
                     RPGHRHIWLEDGTVLRDVLPSTPLAEITERLDGLDEDDLLFQSRIIDAALDTIPTPTPA
                     PALTPRLAPAQSPTSDQALTPDPRVTPAQTPAPRPAPRPAAVPAPVRGAEPRPASDSRR
                     ASDSRPASAPASGSGSGSGSALGATGAWTSRWDLAAGSASGLSAGLASRVDVDVAGRVA
                     GSVVAELEGCAVRDGGGRIGWVTTESVDGTTRRVAAAGLDLYGGLPGIGLFLSYFSALT
                     GNNERLAQNVGYEVARRCELAAELPAQDHRFQPHGLGAVYYLAHAAAVHQRPELAECAR
                     AVLLRQQGDASESDVLDGTAGTVFSALALHTVLPDDEILDLARTAGERLLHDAPSGPGF
                     GYGAPGAAVALARLHRLVPDPRFLDQAKRLMLSVNPEEGVGWCRGAEGTATALVAFADA
                     RVPDGEKDDGRGLDDLLLDDGLEGLLARALLAVQGRMSGDDAPEFPDLLGEGPSPADEL
                     DDAGALAAWGGLQLAGSLCHGALSRLELPLPVEPGRDVAAEGRGQRTADSPSASSTAPG
                     FAHALTPSSVPASAFAPCPPTPAPASTSASGAVPASVTLPGLFAGIAGVGFGVLRRARP
                     DLVPSLLTLAPPSRPTPATPGGPASARTQPRRPAHDPPLPWRTPHVRGR"
     gene            4160..5422
                     /locus_tag="P696_RS0129725"
     CDS             4160..5422
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013227.4"
                     /locus_tag="P696_RS0129725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_026415177.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.1e-71,
                     bitscore: 233.2, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.3e-10, bitscore:
                     32.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDVEPDQLAIDGAHPVRTEPWPTYDKGDVFIDDEDLDLVLETI
                     RARLYFRYDHRPHELTQTGGLERDLAAFFGVRHALACASGTTAIALGLLALDLPPGSAV
                     ACPAFTFAATPSAIRLAGHRPVLVECDDDLHLDVADLRRRMTPEIRAIVVVHMRGFASD
                     MDAVLEVAREFGVPVVEDAVPALGARLRGRQLGTFGDVGAFSTQSDKSLNTGEGGFLLT
                     HDPALHARAIVYAGAYEGRMARHFDGDPPPVDDLAMPIFGLRMDEIRAALARGLLRRLP
                     ERLEAHHRNYDHVAAGLAENPDVALRRPVADHAYLGEALVFRVPGASSAQSAWIAAALR
                     AEGIAARALGDPGDTNVRAFWNWRFLFPEAAKARAEFPVTAARLDEAIDVPLSANLGEK
                     DCDQLVRAVHKVLSARDGRRV"
     gene            5419..6345
                     /locus_tag="P696_RS49035"
     CDS             5419..6345
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656684.1"
                     /locus_tag="P696_RS49035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfotransferase"
                     /protein_id="WP_034487760.1"
                     /transl_table=11
                     /translation="MIKVLYVTGWCRSGTTLIGNLLAELDGVTHVGELRYLWTNGVLGT
                     GTNQSCGCGARIEECPLWSGVLTRVAGGDPERRREFAERAVRRQDASLRTRHTRARLTA
                     ARARSLAVPPAVDDMVRLYEAIAAESGAPVIVDSGKFPAEAAALCGARGVDARVLHVVR
                     DPRATAESWRTAKEYIPPMPPLRSTGYWVGFNLASELVGRAFPERYLRVRYEDFTRDPR
                     AALARVMRMAGLTGEPPVDAGGEAVLHVNHTVTGNPDRLRRGPVRIRRDDRWLGTQPPR
                     DRRLATAVALPLLPAYGYPLVPREKVN"
     gene            6345..6953
                     /locus_tag="P696_RS0129735"
     CDS             6345..6953
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="P696_RS0129735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family protein"
                     /protein_id="WP_026415178.1"
                     /sec_met_domain="PF00881 (E-value: 4.5e-25, bitscore: 81.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFSDVLSRRRMVRSYKRDPVPKDVLDDVLRVVRRAPSAGFSQGC
                     RVVAVTDADTRASIAEIAGEHWYLERGFGPWLSVAPVLLVLGVREDDYHERYRSADKVN
                     DEGEEMNWPTPYWWVDSGALMMLLQTAAIDAGLATGFAIVHRTDDLKDLLGLPGDVAIV
                     GIMAVGYSAEPVERDPADRARLRSRRKPIDELVRRERWS"
     gene            complement(7017..7709)
                     /locus_tag="P696_RS0129740"
     CDS             complement(7017..7709)
                     /NRPS_PKS="Domain: PKS_KR (2-146). E-value: 2.7e-09. Score:
                     29.1. Matches aSDomain:
                     nrpspksdomains_P696_RS0129740_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631349.1"
                     /locus_tag="P696_RS0129740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_026415179.1"
                     /transl_table=11
                     /translation="MRVVIMGGTSGIGRAAAERLAGEGAEVIVTGRDPERLAEVKATVS
                     AAEQVDGTDETQVREFLERTGEFDHLVLAFSPGGIAMGPVAEVGADDVRRMFEGKLFAY
                     LAVIRLAQGRVRGSITMVSSASARAANPGTAVLAAVNGAIERTVPPLAAELAPVRVNAV
                     APGLIDTPWWSFVPEDQRSATFGRFTRELPVPRAGRSEEVADAIAYLVSSGYVTGTILP
                     VDGGATIS"
     aSDomain        complement(7272..7703)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_P696_RS0129740_PKS_KR.1"
                     /evalue="2.70E-09"
                     /label="P696_RS0129740_PKS_KR.1"
                     /locus_tag="P696_RS0129740"
                     /protein_end="146"
                     /protein_start="2"
                     /score="29.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVIMGGTSGIGRAAAERLAGEGAEVIVTGRDPERLAEVKATVSAA
                     EQVDGTDETQVREFLERTGEFDHLVLAFSPGGIAMGPVAEVGADDVRRMFEGKLFAYLA
                     VIRLAQGRVRGSITMVSSASARAANPGTAVLAAVNGAIER"
     CDS_motif       complement(7614..7700)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_P696_RS0129740_0001"
                     /evalue="1.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="P696_RS0129740"
                     /protein_end="32"
                     /protein_start="3"
                     /score="17.6"
                     /tool="antismash"
                     /translation="VIMGGTSGIGRAAAERLAGEGAEVIVTGR"
     gene            7781..8365
                     /locus_tag="P696_RS0129745"
     CDS             7781..8365
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009072727.1"
                     /locus_tag="P696_RS0129745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_026415180.1"
                     /transl_table=11
                     /translation="MTGQRGPGRPRSEAARRAILDAAMEALQERGYAALTMQGIAARAG
                     VGKQTVYRWWPSKADVVLEAMAGMADEMVAVPDEGSLEADLDAFLAATFHQRGQRAVLV
                     GLMAEALLDPAFAAQFKERFLLARRAVFRSILERAAARGEVAPDVDLDLLGDIVYGVLW
                     YRLMLGHAPLDEDLGRRLSRLVAREASRAPD"
     gene            complement(8461..9153)
                     /locus_tag="P696_RS0129750"
     CDS             complement(8461..9153)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1286: Pentapeptide
                     repeat protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653237.1"
                     /locus_tag="P696_RS0129750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_026415181.1"
                     /transl_table=11
                     /translation="MSGSNTGSNTPRQPRRPRPPRLPQGLSPAGRDHAELVHDAKFLSL
                     EYGALDLFTPEDDPEDVTFERCRFTDTRLAGLTLHRAGFADVAFHGCDLANLRLFDSRF
                     FTTAVTTCRMTGTQFTEAGLRDVTFEGCRADLAGFRFAVLRNVVFRDCNLTEANFQNAE
                     LRDVRFEGCTLVAAQFSQASVRDVRFEGCDLSGLGGVDGLDGATVGASDARTLLPSFAA
                     ALGVTIED"
     misc_feature    9129..9144
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.02"
                     /tool="antismash"
     misc_feature    complement(9130..9143)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.48"
                     /tool="antismash"
     gene            9227..9838
                     /locus_tag="P696_RS0129755"
     CDS             9227..9838
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025343.4"
                     /locus_tag="P696_RS0129755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_026415182.1"
                     /transl_table=11
                     /translation="MPKKVDHEQRRRQIAEALLRIAGARGLQAATMREVAAEAGVSVRL
                     VQYYFDSKLELLLGAVPFLGEQMSARMVARIGEESGGASPPSPRAVLEGALTAVMPLDD
                     EGRRLWRTYNAYFILVLDDPDFAARVGSPHHSATDRFLAEHITRAQEAGQIDPELDALT
                     TAAGLFTMAQGLGSGVMAGHRDGAEAREILVYHLDRLFRR"
     misc_feature    complement(9850..9867)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            9899..10717
                     /gene="atpB"
                     /locus_tag="P696_RS0129760"
     CDS             9899..10717
                     /EC_number="7.1.2.2"
                     /GO_component="GO:0000276 - mitochondrial
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA]"
                     /GO_component="GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA]"
                     /GO_component="GO:0045264 - plasma membrane
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA]"
                     /GO_function="GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA]"
                     /GO_process="GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /gene="atpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629362.1"
                     /locus_tag="P696_RS0129760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="WP_026415183.1"
                     /transl_table=11
                     /translation="MPTASSAPSVSALASGSGEFRAPGGELFEWGPLWPGVLPDWITKP
                     VLLIVLSAVAVVVFAWRAFGRPELVPRGVQNVGEIGYLFVRDQIARPMIGKDGDRWMPF
                     LLPLFLFVLAMNLMGDVPVLQLPATSHFAMPLLLALVCYALYLVISVRRQGFAGYFRNI
                     MFPPGLPVWVYVFYAPIELLQHLVLRPFTQSVRLFANMFAGHILLAFFATVAWWFLLEK
                     PTVAGFGLGVVGVLMSVVLTAFEIFVQVLQAYIFTLLAASYIGGALHPDH"
     gene            complement(10740..11936)
                     /locus_tag="P696_RS0129765"
     CDS             complement(10740..11936)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653890.1"
                     /locus_tag="P696_RS0129765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_026415184.1"
                     /sec_met_domain="p450 (E-value: 2.2e-22, bitscore: 72.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVRYSPFDFDVQKDPYPIFARLREEAPVHRNDEDDIWVLSRHED
                     VEAALRDSARFSSVNGLRIEPAFWGPDAERFFSFVAMDPPKHTRMRGLVSRAFTAKRVA
                     ALEPRLREIARGHLAPLLEAGEFDLMSDFAARFPTDVISELVGVPESDRDRVRDLGSAI
                     MHRPEDVPGPVTDLPPEALQAIGELVGYYTQLTIERAKERRDDLLSGLLDATEGEDRLT
                     PEEIVGVLILLVGAGIETSMLLLGNCWHAAWTHPDARAAALRDGRVDAWIEETLRYDTP
                     SQALARTATEDVELHGVTIPKDGRVLSLLGSANRDPRVFDDPDTFDLDRDTGRALSFGI
                     GRHHCLGSALGRLEARIALTEIAAAVADFELDESGVKRIYSSNDRGFAALPTRITARR"
     gene            12078..12893
                     /locus_tag="P696_RS0129770"
     CDS             12078..12893
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653889.1"
                     /locus_tag="P696_RS0129770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_026415185.1"
                     /transl_table=11
                     /translation="MSVERAPRGIDPSKPHPARRYNYWLGGKDNFEADRVSGEAVASGF
                     PTIRHAAIENRRFMQRAVRYLAEEAGVRQFLDVGTGLPSAGNVHEIAQEIDPASRIVYV
                     DNDPIVLVHARALLTSSPEGATAYLDSDLREPERILADPALHKTLDLTEPVALMLVAIT
                     HFLTDEDDAYGTVRTLVDALAPGSFVVITNATQDHLTAEERAAVDEANQRSGIPFRNRS
                     RAEFARFFDGLDLVDPGVGSVIEWRPDAAREQGPSVKQVSMHGAVARVP"
     misc_feature    13945..13960
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.32"
                     /tool="antismash"
ORIGIN
        1 cctcccccca gccccgaacc agccacccac ccaccccgcc cccagccgga caccaacaca
       61 ccccgctccg agccggacac cgccgcgcct cgttcggaag cggacgccgc cggacccggc
      121 cctgaggtgg acacctgtgc gctctctccc gaagacgacc ccagcggtcc gcgctctgcg
      181 gcggacgctg tcgcgcccag ttcgggagtg gacgctgccg agccacgctc tgaagcggat
      241 gccgccgggc ctcgccctga ggcgggcgcc tgtgcgctct gtcccgaagg ggacgctggc
      301 gggcgctcgg aggcggattc cgaggcggac acgtgcgcgg ctggggtggg cgtggctggg
      361 gctggctcgg ggtctccggc gtcgacggac gagcttgtgc ctcgatctga tcctctctcc
      421 ccagatacgg atgtgccttt gcctccgcat gcctcacagc cgccggagcc ggatgcgtcc
      481 cgctacgcgg atccggtgct cgacccgctt actggtacgg ggccccgcct ggctcatcat
      541 ccagcgcccg cttgcccgct cgtcgccacg tctcctgcgg cgtcagcgag cggccctggc
      601 cagagcaccc cctcgcagcc actggttcct tccggcgctg ccgaagctgt gggagtgaac
      661 agcgggggcc tggatggcgg tggtgggcgc gcgggggcgc gtgggtgggg gattccttgg
      721 cgggatgcgc tgcgggctgg tgaggacgag gcggtggagc cggactggca tcgcaggttc
      781 cgcgccgcgt acgaggctct cgcgtctctt gacgaggagg cggcggagcc gggggacggg
      841 ctgcctgttg acctggggct tcttgaggtg gcgcggccac tgttgatcgc cgcgcgtcag
      901 gttcttgtcg ccaccctgcc cgacgagctt gtggacgcgc tggctgcgga tctgccgctc
      961 ggttggctct ccatggccgt cgagccgtcc cttgcggggg agcttcgggg cctgggcgag
     1021 gggacccgag ggacggggga agaggggtat cggaggtttg tgcgctcgct gggggagccg
     1081 gaacgggggc tcgcggtatg ggcgcggtac ccggtgctgg cccggcaggt cgtggacgta
     1141 ctggacgggt gggtcggggc tcggcgtgcg ttcgcgcggg atctggtgga cgatctgccc
     1201 gcgcttcgtg aggcgttcgg ccctgagctg ggtgacctcc ggcaggtgat gttcgggtcg
     1261 gcggagacgc atcggggtgg acggacggtg gcgctggtgc ggttcgccgg cgcgaccgtc
     1321 gtgtacaagc cgcgcgggct gggcatcgac ctggccttcg accggttgct gggctggttc
     1381 aacgagcgcg ggccgcggtt cgcgctgcgg cggctgaggc tgctcgaccg gggcgatcac
     1441 ggctggtgcg agttcgtcca ggccgcgccc accagtgtgg gggacgcgcc cgcgctgctg
     1501 tggcggacgg gggcgctgct cgcgctcatg cacgcggtcg gcgggttcga cctgcacgcg
     1561 gacaacgtca tctcggacgg cgcggacccg gtcgtcatcg acctggaggc gctgttccac
     1621 accgggctca cccagccgct cgtccggcgc gcgcggctgg gtgatccggc ggcggaccga
     1681 ctcgccacgt ccgttctgcg gaccggcctg ctgccgggcc cgctcgtcat gccggacgtg
     1741 ttcaccgagc gtccgttcgg cgtggacatc agcccgttcg ggcccgccga gcgccggacg
     1801 ctgatcccca taccgaaggt cgacgacccc ggcaccgacc ggatgcgggt cgggcgcggt
     1861 taccgcaccg tccccgcgcc tcccgggcgg gcccgcaacg aggacggcac gccgctcgac
     1921 ccgcgcccgc accgggacgc gctgcacgac gggcaccgtt tcgcgtaccg ccttctcgcg
     1981 gaggcgggcc cggcgctggt gacctcccgc gacggccggg acggcccgct ggcgggatgc
     2041 ggtgatgtgt cgattcgact cgttcaactt tcgaccttcc tctacatgcg gttgctgctg
     2101 gagagctggc gtccggaggc gatgcgcctc gcggaggagc gggaacgcgg gttcgcccgg
     2161 ctggacgcgg gctggcccgg cgttccggag cgtgcgcgac tgatcggcgt cgagcgggac
     2221 gccctctggc gtggcgaggt tcccgtcttc gaactccggc cggggcaccg ccacatctgg
     2281 ctcgaggacg gcaccgtgct ccgggacgtc ctcccgagca cgccgctcgc cgagatcacc
     2341 gaacgcctcg acggcctgga cgaggacgac ctcctcttcc agtcccgcat catcgacgcc
     2401 gccctcgaca caatcccgac cccgacccca gccccggccc tgaccccaag gttggccccc
     2461 gcccagagcc cgacatcgga ccaggccctg acaccggacc cgagggtgac cccggcacag
     2521 accccggcac cgcgcccggc tccccgcccg gctgcggtcc cggccccggt tcgaggcgca
     2581 gagccacgcc cagcttcgga ctcgcgccgg gcctcggact cgcgcccagc ctcggccccg
     2641 gcttcgggct cggggtcggg ttcgggttcg gccttggggg cgaccggggc ttggacgtct
     2701 cgttgggact tggcggctgg gtctgcgtcg ggtttgtcgg cgggcctcgc gtcgagggtg
     2761 gacgtggacg tggcgggtcg ggtggcgggg tcggtggttg cggagttgga gggttgtgcg
     2821 gttcgggacg ggggcgggcg gatcgggtgg gtgaccaccg agtccgtgga cgggacgacg
     2881 cgccgggtcg cggcggctgg gctcgacctg tacggcgggc tgcctggcat cgggttgttc
     2941 ctctcctact tctcggctct cactggtaac aacgagcgac tggcccagaa cgttgggtac
     3001 gaagtcgcgc gacgttgcga actcgccgcc gaactgcccg cccaggacca tcgcttccaa
     3061 ccgcacgggc tcggcgcggt ctactacctg gcgcacgcgg cggccgtcca ccagcgccct
     3121 gagctggccg aatgtgctcg tgccgtgttg ctgcggcagc agggcgacgc gtcggagagc
     3181 gatgtgctgg acgggacggc gggcacggtc ttctcggcgc tcgcgctcca caccgtcctg
     3241 ccggacgacg agatcctgga cctggcgagg accgcgggcg agcggctgct tcacgatgcc
     3301 ccgtccgggc ccgggttcgg atacggcgcg ccgggcgcgg ccgtcgcctt ggcacggctg
     3361 catcggctcg tccccgatcc gcgattcctc gaccaggcga aacggctcat gctgtccgtg
     3421 aatccagagg agggcgtcgg ctggtgccga ggcgctgaag gcaccgccac cgccctcgtt
     3481 gccttcgccg acgcgagagt tccggacggt gagaaggacg acggccgtgg cctggatgac
     3541 cttctcttgg acgacgggct tgaggggctt ctggctcggg cccttctcgc tgttcagggg
     3601 aggatgtccg gggacgacgc accagagttc cctgacctgc tcggcgaggg cccgtccccg
     3661 gccgatgagc tcgacgacgc tggtgcgctt gccgcctggg gtggcctcca acttgcgggt
     3721 tcgctctgcc acggcgcgct ctcgcgcctt gagcttccgc tgcccgtcga acccgggcgc
     3781 gacgtggcgg cggaaggccg cggacagcgg acggctgatt ctccgtctgc ctcatcgacc
     3841 gcgcctgggt tcgcgcacgc gctgacgcct tcttccgtgc ccgcctccgc gttcgcgccg
     3901 tgcccgccta ctcccgcgcc cgcctcgacg tccgcgtccg gggccgtgcc cgcctccgtg
     3961 accctgcccg ggttgttcgc ggggattgcc ggggttgggt tcggggtgct tcgacgggct
     4021 cgtcccgatc tcgtgcccag ccttctgacg ctcgcgccgc ccagccggcc gacgcccgcg
     4081 acgcccggcg gcccggcgtc cgcgagaacg cagccccgtc gccccgccca cgacccgccc
     4141 cttccctgga ggaccccaca tgtccgtgga cgttgagccg gaccagctcg ccatcgacgg
     4201 cgcacacccc gtgcgcaccg aaccctggcc gacctatgac aagggcgatg tcttcatcga
     4261 cgacgaggat ctcgacctcg tgctggagac gatccgggcc cgcctgtact tccgctacga
     4321 ccaccgtccg cacgagctga cccagaccgg cggcctggaa cgggacctcg ccgcgttctt
     4381 cggggtcagg cacgccctgg cgtgcgcgag cggcacgacc gcgatcgcgc tcgggctgct
     4441 cgcgctggac cttccgcccg gctcggccgt cgcctgcccg gcgttcacgt tcgcggcgac
     4501 gccgagcgcg atccggctgg ccgggcaccg gcccgtgctg gtggagtgcg acgacgacct
     4561 gcacctggac gtcgcggacc tgcgccgccg catgacgccc gagatcaggg cgatcgtcgt
     4621 cgtccacatg cgcggcttcg cctccgacat ggacgcggtg ctggaggtcg cgcgcgagtt
     4681 cggggtgccg gtcgtcgagg acgccgtccc ggcgctgggc gcgcggctgc gcggacgcca
     4741 actcggcacg ttcggcgatg tcggcgcgtt cagcacacag tccgacaagt cgctgaacac
     4801 gggcgagggc ggcttcctgc tcacccacga ccccgccctg cacgcgcgcg cgatcgtgta
     4861 cgcgggcgcg tacgagggac ggatggcgcg gcacttcgac ggggatccgc cgcccgtgga
     4921 cgacctcgcc atgccgatct tcgggctgcg gatggacgag atccgcgcgg ccctcgcccg
     4981 cgggctcctg cgccgcctgc ccgaacggct ggaggcgcac caccggaact acgaccacgt
     5041 ggcggccggg ctcgccgaga acccggacgt ggcgttgcgg cggccggtcg ccgaccacgc
     5101 ctacctgggg gaggcgctgg tgttccgcgt gcccggcgcg agttccgcgc agagcgcgtg
     5161 gatcgcggcg gcgctccggg ccgagggcat cgccgcgcgc gcgctcgggg accccggcga
     5221 caccaacgtg cgggcgttct ggaactggag gttcctgttc cccgaggccg cgaaggcccg
     5281 cgccgagttc cccgtcaccg ccgcccgcct ggacgaggcg atcgacgtcc cgttgtcggc
     5341 gaacctcggc gagaaggact gcgaccagct ggtccgggcc gtccacaagg tgctgtccgc
     5401 ccgggacggg aggcgcgtgt gatcaaggtc ctgtacgtga cgggctggtg ccgcagcggg
     5461 acgacactga tcggcaacct gctcgccgag ctggacggcg tgacgcacgt cggcgagctg
     5521 cgctacctct ggacgaacgg cgtcctcggc accgggacga accagtcgtg cggctgcggg
     5581 gccaggatcg aggagtgccc gctctggtcg ggagtcctca cccgcgtcgc gggcggcgat
     5641 ccggagcggc ggcgcgagtt cgccgagcgg gccgtccgca ggcaggacgc gtcgctgcgc
     5701 acccggcaca cccgcgctcg cctgaccgcc gcgcgcgccc gttcgctcgc cgtccccccg
     5761 gcggtggacg acatggtgag gctgtacgag gcgatcgcgg cggagtccgg cgcgccggtg
     5821 atcgtggaca gcgggaagtt ccccgccgag gccgccgcgc tgtgcggggc gcgcggcgtg
     5881 gacgcccgcg tgctgcacgt cgtccgggat ccgcgcgcca cggccgagtc gtggcggacg
     5941 gccaaggagt acatcccgcc catgccgccg ctgcgcagca ccggctactg ggtcgggttc
     6001 aacctcgcgt ccgagctggt cgggcgggcc ttccccgaac ggtacctgcg cgtccgctac
     6061 gaggacttca cccgggaccc gcgggcggcg ctggcgcgcg tcatgcggat ggcgggcctc
     6121 accggcgaac cgccggtgga cgcgggcggc gaggcggtcc tgcacgtcaa ccacaccgtg
     6181 acgggcaatc cggacaggct gcggcgcggc ccggtgcgga tccgccgcga cgaccgctgg
     6241 ctcggcacgc agccgccgcg cgaccggagg ctcgccaccg ccgtcgccct gccgctgctc
     6301 cccgcgtacg gctaccccct cgtcccgaga gagaaggtga actgatggat ttcagtgacg
     6361 tgctgtcccg acgccggatg gtccggtcct acaagcgcga tcccgtgccc aaggacgtcc
     6421 tggacgacgt tctccgcgtc gtccggcgcg cgccgagcgc ggggttcagc cagggctgcc
     6481 gcgtcgtcgc cgtcaccgac gccgacaccc gcgcgagcat cgcggagatc gccggggagc
     6541 actggtacct ggaacgcggg ttcgggccgt ggctgtcggt cgcgcccgtc ctgctcgtgc
     6601 tcggcgtccg cgaggacgac taccacgagc gctaccggag cgccgacaag gtgaacgacg
     6661 agggcgagga gatgaactgg cccaccccgt actggtgggt ggactcgggc gcgctgatga
     6721 tgctgctcca gacggccgcc atcgacgcgg gcctcgccac cggcttcgcc atcgtccacc
     6781 ggacggacga cctgaaggac ctgctcggcc ttcccgggga cgtggcgatc gtcggcatca
     6841 tggccgtcgg ctactcggcc gagcccgtgg aacgcgaccc cgccgaccgc gcccgcctcc
     6901 gctcacgccg caagccgatc gacgaactcg tccgccgcga acgctggtcc tgaccccagc
     6961 ctcatgagac ggccccggac ggcgcaggca gcgcggtccg gggccggtac ggaaggtcag
     7021 gaaatggtgg cgccgccgtc caccgggagg atcgtcccgg tgacgtagcc ggacgagacc
     7081 aggtaggcga tcgcgtccgc gacctcctcg gaacgtccgg cacgcggtac gggcagctcc
     7141 ctcgtgaacc gcccgaacgt ggcggaacgc tggtcctcgg ggacgaacga ccaccacggc
     7201 gtgtcgatca gcccgggggc gaccgcgttc acccgaaccg gcgccagctc ggcggcgagc
     7261 ggcgggacgg tccgctcgat cgcgccgttc acggccgcga gcacggccgt cccggggttc
     7321 gccgcccgcg ccgacgccga cgacaccatc gtgatcgagc ccctgaccct gccctgcgcc
     7381 agcctgatca ccgccaggta ggcgaacagc ttgccctcga acatccgccg gacgtcgtcg
     7441 gcgccgacct cggcgaccgg gcccatcgcg atcccgccgg ggctgaaggc gaggaccagg
     7501 tggtcgaact cgcccgtccg ctcgaggaac tcccggacct gcgtctcgtc ggtgccgtcg
     7561 acctgctcgg cggccgacac cgtcgccttg acctcggcga gccgctccgg gtcccgcccg
     7621 gtgacgatca cctcggcgcc ctccccggcg agccgctcgg ccgccgcgcg gccgattccg
     7681 gaggtgccac ccatgatgac gacgcgcatc tgcgcactcc cttttctaga cgctatgtct
     7741 cgatattatt cgagacgcac cgtcttgtaa actgccgggc atgaccggac aacgcggccc
     7801 gggccgtccg cgcagcgagg cggcgcggcg ggcgattctc gacgcggcca tggaggcgct
     7861 ccaggagcgc ggctacgccg cgctgaccat gcagggcatc gccgcccgcg cgggcgtggg
     7921 gaaacagacg gtctaccggt ggtggccgtc caaggcggac gtcgtgctgg aggccatggc
     7981 cgggatggcg gacgagatgg tcgccgtccc ggacgagggg tcgctcgagg ccgacctgga
     8041 cgccttcctc gccgcgacct tccaccagcg cgggcagcgc gccgtcctgg tcgggctgat
     8101 ggccgaggcg ctgctcgacc cggcgttcgc ggcccagttc aaggaacggt tcctgctcgc
     8161 ccggcgcgcg gtgttccgct cgatcctcga acgcgccgcc gcccgcggcg aggtcgcgcc
     8221 ggacgtcgac ctcgacctgc tgggcgacat cgtctacggc gtcctctggt accggctcat
     8281 gctcggccac gccccgctcg acgaggacct cggccgccgc ctgagccgcc tcgtcgcccg
     8341 cgaggcatcc agggcccctg actgaggagg ctcagtcgcg ggcgtccgtc accgagagac
     8401 tcggtcgtcg atcgtccgtg accgagagac tcggtcgtcg accgtccgtg accgagaggc
     8461 tcagtcttcg atcgtgacgc cgagcgcggc ggcgaaggac ggcaggagcg tgcgcgcgtc
     8521 ggacgcgccg acggtcgcgc cgtccaggcc gtccacgccg ccgaggccgg agaggtcgca
     8581 gccctcgaac cggacgtccc ggacggacgc ctggctgaac tgggcggcga ccagcgtgca
     8641 gccctcgaac cggacgtcgc gcagttcggc gttctggaag ttcgcctcgg tgaggttgca
     8701 gtcgcggaac acgacgttcc ggagcaccgc gaagcggaat ccggccaggt cggcgcggca
     8761 gccctcgaac gtcacgtcgc gcaggcccgc ctcggtgaac tgcgtgccgg tcatccggca
     8821 ggtcgtgacc gccgtggtga agaaccggga gtcgaagagc cgcaggttcg ccaggtcgca
     8881 gccgtggaac gccacgtccg cgaagcccgc gcggtgcagg gtcagcccgg cgagccgcgt
     8941 gtcggtgaag cggcagcgct cgaaggtcac gtcctccggg tcgtcctcgg gggtgaacag
     9001 gtcgagggcg ccgtactcca gggacaggaa cttggcgtcg tggacgagtt cggcgtggtc
     9061 gcgtccggcg ggggagagcc cctgggggag acgcggcgga cgcggccgac gtggctgacg
     9121 cggggtgttc gaacccgtgt ttgaccctga catgccgccg accgtacccg actcgaccgt
     9181 aatctggccc ggtcggattc ccacagaacg acggaggcca gggcgcgtgc cgaagaaggt
     9241 cgaccacgag cagcgccgca ggcagatcgc cgaggcgctg ctgcggatcg cgggcgcgcg
     9301 cgggctccag gcggccacga tgcgggaggt cgccgccgag gccggagtgt cggtccggct
     9361 cgtccagtac tacttcgaca gcaaactcga actgctcctc ggcgcggtgc cgttcctggg
     9421 ggagcagatg tcggcgcgca tggtcgcgcg gatcggggag gagagcggcg gcgcgtcccc
     9481 gccgtccccg cgcgcggttc tggagggcgc gctcaccgcg gtcatgcccc tggacgacga
     9541 gggccgacgg ctctggcgca cctacaacgc ctacttcatc ctcgtcctgg acgatcccga
     9601 cttcgccgca cgcgtcggtt cgccgcacca cagcgcgacc gaccgcttcc tcgccgagca
     9661 catcacgcgc gcgcaggagg ccgggcagat cgaccccgag ctggacgccc tgaccacggc
     9721 cgccggtctc ttcaccatgg cgcaggggct cggctccggc gtgatggccg gacaccggga
     9781 cggcgcggag gcccgcgaga tcctcgtcta ccacctggac cggctgttcc ggcgttagtg
     9841 atacgcctgt accatctcta agtggtacag gcgtatcatc atgttccggg agggtcgcat
     9901 gccgaccgcg tcgtccgcac cgtccgtgtc agcgctcgca tcggggtccg gggagttccg
     9961 cgcccccggc ggggagctgt tcgagtgggg gccgctctgg ccgggcgtcc tgcccgactg
    10021 gatcaccaag ccggtgctgc tgatcgtgct ctcggccgtg gcggtcgtcg tgttcgcctg
    10081 gcgcgcgttc ggccgtccgg agctcgtccc gcgcggggtc cagaacgtcg gcgagatcgg
    10141 ctacctgttc gtccgcgacc agatcgcgcg gccgatgatc ggcaaggacg gcgaccggtg
    10201 gatgccgttc ctgctgccgc tgttcctgtt cgtcctcgcc atgaacctca tgggggacgt
    10261 gcccgtcctg cagctgcccg cgacctcgca cttcgcgatg ccgctgctcc tcgcgctggt
    10321 ctgctacgcg ctctacctgg tgatcagcgt ccggcggcag gggttcgccg gatacttccg
    10381 gaacatcatg ttcccgcccg gactgccggt ctgggtgtac gtcttctacg cgccgatcga
    10441 actgctccag cacctggtcc tgcggccgtt cacgcagtcg gtgcggctgt tcgcgaacat
    10501 gttcgccggg cacatcctgc tggccttctt cgcgaccgtg gcctggtggt tcctcctgga
    10561 gaagcccacg gtcgcggggt tcgggctggg cgtggtcggg gtgctgatgt cggtggtgct
    10621 gaccgcgttc gagatcttcg tgcaggtcct gcaggcgtac atcttcacgc tgctcgccgc
    10681 gtcctacatc ggcggcgccc tgcaccccga ccactgagcc cttccccggg gcgcgcgggc
    10741 taccggcgcg cggtgatccg ggtcgggagg gcggcgaagc cgcggtcgtt ggacgagtag
    10801 atgcgcttca cgccggactc gtccagctcg aagtcggcga ccgcggcggc gatctcggtc
    10861 agcgcgatgc gcgcctccag ccgtccgagc gccgagccga ggcagtggtg gcggccgatg
    10921 ccgaacgaca gcgccctgcc cgtgtcacgg tcgaggtcga aggtgtcggg gtcgtcgaag
    10981 acgcgcgggt cgcggttcgc cgagcccagc agggacagga cgcggccgtc cttcgggatg
    11041 gtgacgccgt gcagttcgac gtcctcggtc gcggtccgcg cgagcgcctg cgagggcgtg
    11101 tcgtaccgca gggtctcctc gatccacgcg tccacccggc cgtcgcgcag cgcggcggcg
    11161 cgggcgtccg ggtgcgtcca ggcggcgtgc cagcagttgc cgagcagcag catggacgtc
    11221 tcgatcccgg ccccgaccag caggatcagc accccgacga tctcctcggg ggtgagccgg
    11281 tcctcgccct cggtcgcgtc cagcaggccg gagagcaggt cgtcgcggcg ctccttggcg
    11341 cgctcgatcg tcagctgcgt gtagtagccg accagctcgc cgatcgcctg cagcgcctcc
    11401 ggcggcaggt cggtcacggg gcccggcacg tcctccggac ggtgcatgat cgccgagccg
    11461 aggtcgcgga cccggtcccg gtcggactcg gggacgccga ccagctcgga gatcacgtcg
    11521 gtcgggaacc gcgcggcgaa gtcgctcatc aggtcgaact cgcccgcctc cagcagcggc
    11581 gcgaggtggc cgcgcgcgat ctcgcgcagc cgcggctcca gcgcggcgac ccgcttggcc
    11641 gtgaacgccc gggacaccag gccgcgcatc cgggtgtgct tcggcgggtc catcgcgacg
    11701 aacgagaaga agcgctcggc gtccgggccc cagaacgcgg gctcgatgcg cagcccgttc
    11761 acgctggaga accgcgccga gtcgcgcagc gccgcctcga cgtcctcgtg ccgggacagg
    11821 acccagatgt cgtcctcgtc gttccggtgg acgggggcct cctcgcgcag gcgcgcgaag
    11881 atcgggtacg ggtccttctg gacgtcgaag tcgaaggggc tgtagcggac actcatgggg
    11941 aagggccttc cgcgtcgtcg cgaccgaagg agacgatcat ggccggaaaa tcccccgcga
    12001 tccaccccgc aacgcgtgaa cacctcagca tccggcacaa ttgatcacgc atcaccccgc
    12061 tcgaaacgag gtgcaccgtg agcgtcgagc gcgcccccag ggggatcgac cccagcaagc
    12121 cgcatccggc ccgccgctac aactactggc tcggcggcaa ggacaacttc gaggccgacc
    12181 gcgtctccgg cgaggccgtc gcgtccgggt tccccacgat ccggcacgcc gcgatcgaga
    12241 accgccgttt catgcagcgg gccgtccggt acctcgcgga ggaggcgggc gtccggcagt
    12301 tcctggacgt cggcaccggc ctcccctcgg cgggcaacgt ccatgagatc gcccaggaga
    12361 tcgacccggc gagccgcatc gtctacgtgg acaacgaccc gatcgtcctc gtgcacgcgc
    12421 gcgccctgct gaccagctcg cccgagggcg ctaccgccta cctggactcc gacctgcgcg
    12481 aacccgagcg catcctcgcc gacccggccc tccacaaaac cctggacctg accgagccgg
    12541 tcgcgctgat gctggtcgcc atcacccact tcctcaccga cgaggacgac gcgtacggca
    12601 ccgtccgcac cctcgtcgac gccctcgccc cgggcagctt cgtggtcatc accaacgcca
    12661 cccaggacca cctcacggcc gaggaacgcg cggcggtgga cgaggcgaac cagcgcagcg
    12721 gcatcccctt ccgtaaccgc tcccgcgccg agttcgcccg cttcttcgac ggcctcgacc
    12781 tcgtcgaccc cggcgtcggc tcggtcatcg aatggcgccc cgacgccgcc cgcgagcagg
    12841 gcccgtccgt caagcaggtc tccatgcacg gcgccgtcgc ccgcgtcccc tgacccgccg
    12901 gcctactgcc gcgacagcac ccgtgacgcc ccggcgatga tcgtcgtcgc caggatccac
    12961 ccggacgccg tgagcgccga ggccagccac tggtacccgc cgcgcggcgc gaacgcactc
    13021 tcctgcccga agctcacgat cggcagaagc aggtcaagcg catagaggaa cgggttgaac
    13081 cctggcgtct cgtccttctt cagcgacggc gggtggtgcc cggcgaacac gaccgtcccg
    13141 agagccagca gggcgacgag ccacgcagcg gcgcgctgcg gccgataccc gtagccgacc
    13201 gtccagtcct gcagaaaccc ccagatccgc agcggaacct gttggatgcc ccgacgccgt
    13261 cgctgtttgg ctagcagaac gtcccgggcg gctgcgtcat gtcccgtccg ccgatacacg
    13321 gcagccaggt gctcgtaggg ctgcggaatg tatccgtcgg tgtcccgcat cagcagttgc
    13381 aggcgaccgg ccaccggcat gggccggtgc agagagtcgt aggcgaaccc gtccagacgc
    13441 accgatccgg gccaggcact cgggtaatcc gccaggacgc cggtcgaggc atggcgcagg
    13501 tccgccctgc ccaggatcct cgtcgtctcg cccagccgca gaacgccgga ccgcgaccgc
    13561 ttgagctcca gattcccctc gacacgcgct ccgtcgaaac acaggtcgcg cccgatctca
    13621 gcggacgtga acgagacccg cccggccgcc acgaacccct cgcaacagtc caccttgccg
    13681 tcggtcctga tgcgcgcggc gctgacggcg gccgagccgg ggttggagac gtgcgcgttc
    13741 ttgaagctga tggtgccccc cacctgggcg tcggtgagga cgatctcgcc ggtcacctcg
    13801 gcctccttca gcatcagggg gccgttcagg gacgcgccgg acagcgacaa cgcgaccttc
    13861 ccggggttgc cgaggcgggc ggcggtgagg tcgcagcggc ggccgatgcc ggcgtcctgg
    13921 aggcggaact cgccggacga ctccaggcgg tgggcgaaca ggccgtcctc ggcggtcagg
    13981 ccgtcgccgt cgaacgcgac gccgccgggg ttggcgaggc gggtgccgga gaggtccagg
    14041 atgccgccga ccttggcgac gttcaggcgg agcgggcctt cgacgtggga tccgcggagg
    14101 ctgagaccgc cgttgatgtg ggtgccgacg gcctggaggg cggggaggcg ggtgttgacg
    14161 agggtgaggg cgggga
//
