LOCUS       NZ_JADG01000004        21089 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Actinomadura oligospora ATCC 43269 P696DRAFT_scaffold00003.3_C,
            whole genome shotgun sequence.
ACCESSION   NZ_JADG01000004
VERSION     NZ_JADG01000004.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Actinomadura oligospora ATCC 43269
  ORGANISM  Actinomadura oligospora ATCC 43269
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 1044562)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2014) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            environment                       :: Soil
            investigation_type                :: bacteria_archaea
            project_name :: Actinomadura oligospora ATCC 43269
            sequencing_meth                   :: WGS
            ref_biomaterial                   :: ATCC 43269
            GOLD Stamp ID                     :: Gi22378
            Type Strain                       :: Yes
            Isolation Site                    :: soil, India
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2013-09-10
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000518265.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 02:24:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,332
            CDSs (total)                      :: 8,253
            Genes (coding)                    :: 8,185
            CDSs (with protein)               :: 8,185
            Genes (RNA)                       :: 79
            rRNAs                             :: 7, 2 (5S, 16S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 7 of 68
            Pseudo Genes (incomplete)         :: 65 of 68
            Pseudo Genes (internal stop)      :: 1 of 68
            Pseudo Genes (multiple problems)  :: 5 of 68
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:28:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 351288
            Orig. end                         :: 372377
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADG01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..21089
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21089
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21089
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11089](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11089
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    98..113
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    100..114
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.03"
                     /tool="antismash"
     gene            415..909
                     /locus_tag="P696_RS0106165"
     CDS             415..909
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="P696_RS0106165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="WP_021597992.1"
                     /transl_table=11
                     /translation="MPSEYAKALGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLGPTPKLVIDLERLQQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPTELTEELIGWGVLDPEARRAVES
                     F"
     gene            complement(1029..2447)
                     /locus_tag="P696_RS0106170"
     CDS             complement(1029..2447)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657351.1"
                     /locus_tag="P696_RS0106170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_245627528.1"
                     /transl_table=11
                     /translation="MLAFLGVVAYSLSMAVLTPAMPLVQRDLHTSAAGAAWGLTAMMLS
                     AAVSTPVVGRLGDLYGPRRVLLVVLGVATAGTVLAAIAPSLGVLLAGRALAGIGGGVFP
                     LAYTVIRSVLPPARTASAVGLMSSMLGLGGAPSWCVAGPVIDLLGWRWLLWMPVLGLVP
                     GLVLAWRLVPQVPGRPGAGVDWWGAGLFSAWMVAALTALTQGMSWGWTSAGVLGLAGAA
                     VVLAAVWWVVERRVDEPLVDPRLMRVRGVWTANAASLLAGYGLMAGGVLFPLLVQAPRP
                     TGFGGSATAAAMLQLPASVGMTLAGIAAGRLHHRVGSRAVLMAGAVLTGAGYAFVALAH
                     GAMWELYVGGTARGVGLGLAYAAVANLVVAAVEPAQTGVATGVNTLLRTVGGSLGTQVS
                     AVILTASAVHGHPGGTGYTTGFTVTAASMAGVLALALAAPGRRGRGRGRATRRSEALDP
                     DAHEPASTRPSAQR"
     misc_feature    complement(2558..2573)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     misc_feature    2810..2825
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    3490..3505
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     gene            complement(3604..4125)
                     /locus_tag="P696_RS43640"
     CDS             complement(3604..4125)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853345.1"
                     /locus_tag="P696_RS43640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_051466953.1"
                     /transl_table=11
                     /translation="MTTLTRGARSATHNVAGAAQHEAPRQRPRALPAPRPAHTAVGQLH
                     AARAGLAEAAEATTPAVRYVSAHLAALRAAAAVLAAHQPLDLTRRRARPRSVWVLLPEA
                     DPALREWAAYFAAGADKRAAAEAGLPRAVTPREADELLHDAEIFVTLVEDTLGVPIQQS
                     LPTTNTNRAS"
     misc_feature    complement(4270..4285)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.93"
                     /tool="antismash"
     misc_feature    4271..4284
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 24.0"
                     /tool="antismash"
     gene            complement(4429..5361)
                     /locus_tag="P696_RS0106180"
     CDS             complement(4429..5361)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="P696_RS0106180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_026411640.1"
                     /transl_table=11
                     /translation="MDVDVPGLRAFVAAAEEMHFGRAAQRLFLTQQALSQRVRRLESVL
                     GAPLFERTTRRVELTDAGRRVLPRARETLNAIDSVMAAVRGEPPRLRVDVYDQRFSPMT
                     LVRGLLDRESRLRVEVSMRQGFEQAVPALLSGEIDAAFGQARDLPGRWPSGLASRVVQL
                     VPMQAFVGPDHPLAGRDAMRPDELRDIGVVMPDPVASEARAFLTRLAGRFGIPIRFVEP
                     AVGLWHYGELVAREEHAVALGEAGIELPEGTELHRIRLVDPVPLVPWCLTWRSGDTSAA
                     LRTVLRLLPAAVPPPPDDLSHWLADDYRD"
     gene            5452..6030
                     /locus_tag="P696_RS0106185"
     CDS             5452..6030
                     /GO_function="GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132713.1"
                     /locus_tag="P696_RS0106185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="WP_026411641.1"
                     /transl_table=11
                     /translation="MTNPPHQLSEDVFQRLLRERIVFLGQEVDDAIANRLCAEILLLSA
                     EDPQRDIQLFINSPGGSVTAGMAIYDIMQFVPNDVATLSLGFTASMGQFLLCAGAPGKR
                     YALPHARILMHQPSGGIGGTATDIRIQTENMIATKRLMQRLIASHTGQSAERIEADSDR
                     DRFFTAEEARAYGFVDHVIDNARALPAAA"
     gene            6076..6543
                     /locus_tag="P696_RS0106190"
     CDS             6076..6543
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291495.1"
                     /locus_tag="P696_RS0106190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_034483705.1"
                     /transl_table=11
                     /translation="MHPNAERVAGVLREQGADGEIIELPDSARTAQAAADQLGCEVGAI
                     ANSLVFDADGAPLLVLTSGAHKVDTARVAALVGAGRVRRATPEFVREHTGQPIGGVAPV
                     GHPAPIRTLVDVWLDKHERVWAAGGHPHTVFPTSYEELLRVTGGDAAEVGE"
     gene            6548..6898
                     /locus_tag="P696_RS0106195"
     CDS             6548..6898
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853348.1"
                     /locus_tag="P696_RS0106195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arsenate reductase family protein"
                     /protein_id="WP_026411643.1"
                     /transl_table=11
                     /translation="MEIWHNPRCSKSRAAKAALDEAGVAYTERRYLDEPPTAAEFDRTL
                     TAIGAEPWEVARLGEAVAKELDLKNLPHDRDRWIEVMVANPVLIQRPIIVTDGSAVVAR
                     DEESVQRALGDA"
     gene            7135..8136
                     /locus_tag="P696_RS0106200"
     CDS             7135..8136
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="P696_RS0106200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_026411644.1"
                     /transl_table=11
                     /translation="MTAEMRTGPASRDGDFRGIDPPALDQLLRQVQQANTAIRGWLAGH
                     RPPPGVSASGYRQAEAVGQWASDQIGMLSRRYNFAITHPDDGGGVHVPPSPAPSPGPSG
                     GSGGGGGGGTSGPGKVTPPRTHKRPHRTTPNGAGDLGGFTTPEAAARAARKDALAIDDA
                     IKHHRPVPAETWKHLTEHAGDPDYTRSLYERLGPSGAAELIKAAHGNPARLKAVERSLG
                     VASHHVTMNARWLDALLDESDRLGDHTSAVHVLTTAHTSARTRDALTKLGLLHQGSPHA
                     PHHTPQPPRHPVQPPATSAGPAFETATLVSDTKAPGTTIPEAKVPETKGCPT"
     gene            8133..8465
                     /locus_tag="P696_RS0106205"
     CDS             8133..8465
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630829.1"
                     /locus_tag="P696_RS0106205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_026411645.1"
                     /transl_table=11
                     /translation="MSPPPPPASLPAPLEGAAAAQLAPHEKPNPEYRQIYQAYSDAYGS
                     IDALRNALDAPVRTLNGTDAWIGPESRAWGGQLETQRAALRKAADQILWDIYNRLAGTQ
                     RTIVRV"
     gene            8477..9085
                     /locus_tag="P696_RS0106210"
     CDS             8477..9085
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658565.1"
                     /locus_tag="P696_RS0106210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_245627529.1"
                     /transl_table=11
                     /translation="MRKREPKLRRLDESAFLRRLDPILQVYAAAMRPPGEQLPGRYSIM
                     QRHTTYPRFRAYVLEQPRPVPGIPGSVRGFAYGFHGEAGQWWHDVVRRALVERDGPEHA
                     DYWLDDAFEVAELHVHPEAQGYGHGRALLNALCEGRRERTVVLSTLDLDRESPARRLYR
                     SVGLRDLLTDFDFPGGGPPYAVMGGTLPLAPYPASSSSS"
     gene            complement(9022..9957)
                     /gene="metF"
                     /locus_tag="P696_RS0106215"
     CDS             complement(9022..9957)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630831.1"
                     /locus_tag="P696_RS0106215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_026411647.1"
                     /transl_table=11
                     /translation="MRRPNPDRAPTIRELLATGEPSFSFEFMPPKTAEAARTLWRTIRE
                     LEPLNPTFVSVTYGAGGSTRDNTVDVVERIATETTMTPVAHFTAVDHSQAELRHLIGRF
                     ASAGVRNILALRGDPPGDPSAEWVKHPEGLEYASDLVRMIRSYGDFCVGVAAFPYKHPR
                     SRDIESDTRFFVEKCRAGADYAITQMFFRADDYFRLRDRVAGEGCDVPIIPGIMPVTRI
                     TTIEKSEQLSGAPFPPEVRERFDAVRDDPEAVRRLGIEHAAELCRDLLDQGAPGIHFIT
                     FNRSTATREVYELLEDAGYGARGSVPPITA"
     gene            10001..11089
                     /locus_tag="P696_RS0106220"
     CDS             10001..11089
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622278.1"
                     /locus_tag="P696_RS0106220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_026411648.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-48, bitscore:
                     161.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSSSGPSPVSTATGQFRKEVDEALHAFVDRQAPGLLAISEDLR
                     PMITALSALLSGGKRLRPAFCFWGWRAAGGLDGPEIAAAAASLELLQASALVHDDVMDA
                     SDTRRGQPSVHRRFEALHAERGWRGPADTFGEGAAILLGDLLLAWSGEMFETSGLSEER
                     RARGRGVYDVMRTEVMCGQYLDMLESTRAGGTVESALRVVDFKSAKYTIERPLHLGASL
                     AGGSEELTAALRAYGRPLGMAFQLRDDVLGVFGDPSQTGKPAGDDLREGKRTVLVALTL
                     ERATPDQAATVDRLLGDPELSGLGVADLREIITGTGGLAACEEMIVRFAAEAREALAAA
                     PVTGEAREALTELAVAATARSF"
     misc_feature    complement(11113..11133)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            11170..11808
                     /locus_tag="P696_RS0106225"
     CDS             11170..11808
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658562.1"
                     /locus_tag="P696_RS0106225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_245627530.1"
                     /transl_table=11
                     /translation="MIGGRKYGMASDTPPAEDIPSAEHAAPAEHAPPAQNATSADAPRI
                     APLPSGEWDDTLRAVVAATGPLNVFTTLARHPALFTAWIGFGSKLLFEGTLDGRVREIA
                     ILRVAHQRSCAYEWAHHVPIAQLAGLDETEIEALRGAPDDHPWSADDRAVIDAADELDA
                     TSTVSDATWAALAKRFDAARLIELVMLIGQYHMVAFALNALRVQIEDDH"
     gene            11808..14030
                     /locus_tag="P696_RS0106230"
     CDS             11808..14030
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658561.1"
                     /locus_tag="P696_RS0106230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="WP_084336874.1"
                     /transl_table=11
                     /translation="MRARTSRTAGATRTRTRTGRVWGAGALASALVVSVWAVQSAEAQP
                     GRAAKAAASTRCGDPATRPWCRRTLTADQRVALLLPKMTADEKISLLASDDPLGGPLGG
                     FSENAHADTSGGITRLGIPPVYMADGPAGVRQGKATALPAPITVAAAFDPNAARDYGST
                     VAWEARHRGNDLIFGPTVDVLRSPRDGRSFEGFGEDPFLSAATGTSWIKGAQAQGVMTS
                     VKHMAVYTQETDRMALKMKVDPRTLREIYLPPFEAAVKTGNAATVMCGFGQLNGRWACQ
                     DDASLNKILRREWGFKGFVASDHTAAQDTPGAANGGLDLELPYGYRYNNLALKAALAQK
                     QVTWTTVDAHARAILRTMFAFGLFDRPAYANDLTKISRAGSEAAAQRIEENGITLLKNG
                     GVLPLKAPKKIALIGGAADANPSGFGSAQVQPFTSVTPRQGISRRAGAGAAITYTSGRN
                     QGDAAKAARHADVAIVFATDSEGEFFDRSCLTLNCGDPLKGDQDGLISAVADANPNTVV
                     VLETGGPVLTPWAGKVKGIVEAWYPGARGGDALARVLYGDVDPGGRLPFTFPAAEGDAP
                     TAGNPAQFPGVDKTVTFSEGVLVGYRHYDAKGIAPRFPFGFGLSYTTFRYSGLKVTPTS
                     VRVTVTNTGSRTGTAVPQLYLGLPAPNVTTPQPPRQLKGFQKLTLAPGASSTVTFPLTD
                     RSLAFWDTPSGAWKVAPGCYRVQLGGSSRDAALTGSFTRGGGACRA"
     gene            14150..15091
                     /locus_tag="P696_RS43645"
     CDS             14150..15091
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853354.1"
                     /locus_tag="P696_RS43645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_034483347.1"
                     /sec_met_domain="Pkinase (E-value: 9.3e-48, bitscore:
                     158.7, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.6e-06, bitscore: 24.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDPSSSRPGLPLGPDDPRRLGGYRLVRRLGEGGQGVVYLAVPRD
                     SGGAHVAVKLLRGGAAATPRARSRFVKEADAAAEITNRHVARVLEADVTGDRPYIVSEF
                     VDGPSLQESVEEDGPLTPGRLRHVALRTAAALAAIHRAGVVHRDFKPGNVLLGPDGPKV
                     IDFGVAQTADATPVTTHGAVGTPAYMAPEQIEDEPVGPPADVFAWAATVVFAATGRPPF
                     GGGASAAVMRRIVTRPPDLGDLDGELRDLVEHCLDKNPAARPTARQVVRALRDGEATAP
                     KPRPKKIPRYRWRMMLALAAVVTAGFALGILL"
     gene            complement(15171..15824)
                     /locus_tag="P696_RS43650"
     CDS             complement(15171..15824)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="P696_RS43650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_211245643.1"
                     /transl_table=11
                     /translation="MGNAMNLPLARRLTGTAGLAAAAALLLEVPLYFVYSGAPPASNVL
                     SRLLIGVLGLGFVLAFAMSFRELIIQAAPESAWIGRFAGGAGLAYGVVTLVSSGLEAGA
                     VIASDHPIDPTVTVDGTYILYGTIGRMLLAMFLGSVGYAILRTSVLPRWAGLFTCGLAL
                     VNLAFMPSLFFGNTPAHFYAANGWGTTALMGAVFSWWLLGTAIGLLRRPKAATA"
     gene            complement(15947..16111)
                     /locus_tag="P696_RS56810"
     CDS             complement(15947..16111)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630836.1"
                     /locus_tag="P696_RS56810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_170026327.1"
                     /transl_table=11
                     /translation="MSVSPDDDRVVDLADEDLPVLPDQTGDDTDAGWGEWRDGGDDDAR
                     FLEERPPHW"
     misc_feature    complement(16177..16197)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            complement(16232..16909)
                     /gene="thiE"
                     /locus_tag="P696_RS0106250"
     CDS             complement(16232..16909)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853356.1"
                     /locus_tag="P696_RS0106250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_245627531.1"
                     /transl_table=11
                     /translation="MSRHLPSDRAVRLRARLGRARLYLCTDAREERGDLPEFLDAVLAN
                     GVDIVQLRQKGLEARQEIEHLRVFRDACDRHDALLAVNDRADVAHAVQADVLHLGQDDL
                     PVPAARAIVGQDVLIGRSTHSDEQAADAAAEPGVDYFCCGPVWPTPTKPGRHAPGLPLL
                     EYAAGRNPARPWFAIGGIDLGNLDQVLATGAERVVVVRALTEADDPGAAAAELARRLHR
                     ADA"
     gene            complement(17077..17460)
                     /locus_tag="P696_RS0106255"
     CDS             complement(17077..17460)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630838.1"
                     /locus_tag="P696_RS0106255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_026411652.1"
                     /transl_table=11
                     /translation="MTQTHATVESDLDPRTDALVGEWIGLREVSERLDIKFNRIKQLLA
                     ERKLLAVRRDGHPMVPAAFIADGQVIKGLPGTLTLLKDAGFDDVETLRWLFTADDTLPG
                     TPVQALAENRGTEVRRRAQALAF"
     gene            complement(17542..18744)
                     /locus_tag="P696_RS0106260"
     CDS             complement(17542..18744)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853358.1"
                     /locus_tag="P696_RS0106260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_026411653.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-49, bitscore:
                     164.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRVMVVGGGLAGVRAAEALRKHGYEGALTMVGAERHRPYDRPPL
                     TKAVLKGETDFPALDTDLAALDVRVLAGERATALRLRPGRGGTLATTAGDLDFDGLVIA
                     TGATPVRMPGDGPQHVIRTLDDALEVRAGLAPGARVVIVGAGWIGAEVATTAAKDGCAV
                     TVVEAADAPLANALGPELGALTAPWYAEAGVELRTGVKVASVEPDGLALAGGGHIPADL
                     VVTGVGVRPEVAWLDGSGLDVERGVLTDASLRASVDGVVRDDVVAVGDCAAWWSNRYGR
                     RLLIEHWDTALNAPETAAATLLGQDAVYDVAPYFWSEQFDRFVQYAGHHAGAERMIRRG
                     SPEDGAWAVAWITGDRLEAILTVDRPRDLVQAKRIIAAGTPVDPVLLGDPGIPVRQSVK
                     S"
     regulatory      18787..18901
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(18857..18870)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            18891..20027
                     /gene="thiO"
                     /locus_tag="P696_RS0106265"
     CDS             18891..20027
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291491.1"
                     /locus_tag="P696_RS0106265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_026411654.1"
                     /sec_met_domain="DAO (E-value: 7.1e-73, bitscore: 242.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVVIIGAGVVGLGAAWRCAARGADVTLVDPEPSSGASGVAAGML
                     TPVSELDYGEEPLLRLGVASRNRYPSFVAELEELTGHDTGHRTDGLLEVAFDADDLRVL
                     EEVKRFQEALGVPTEVLGRRECRRLEPMLAPTVRGGLYAPEDGSIDPRRLTPALLAAAE
                     KLGARLVRRRAAEVIVRGGAAVGVRLDDGEELPADRVLLAAGPWSGDIGGIPPGVVPTV
                     RPVKGQVLRLRTPVPFLRRTVRGVVRGSSVYLVPRADGEIVVGATQEELGFDTRVTAGG
                     LWELLRDARELVPGITELDFAEVTAGLRPGSPDNAPVLGPSALPGLVLGVGHYRNGILL
                     APVSADALSAALLDGELPEVARPFSPDRFSPGRPQEGT"
     misc_feature    18892..18906
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            20024..20224
                     /gene="thiS"
                     /locus_tag="P696_RS0106270"
     CDS             20024..20224
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565075.1"
                     /locus_tag="P696_RS0106270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_026411655.1"
                     /transl_table=11
                     /translation="MKIIVNGEPRDLPEDASVADAVATVTEAPNGVAAALNDEVVSRSA
                     WTATRLTEADRLEVLTAVQGG"
     gene            20221..21018
                     /locus_tag="P696_RS0106275"
     CDS             20221..21018
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630842.1"
                     /locus_tag="P696_RS0106275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazole synthase"
                     /protein_id="WP_026411656.1"
                     /transl_table=11
                     /translation="MTVVPLTEGHDPLVIAGEEFGSRLIMGTGGAPSMSVLGEALAASG
                     TELTTVAMRRVDPSSRGSVLDVLREHGIRVLPNTAGCFTAGEAVLTAKLAREALGTNWV
                     KLEVIADEHTLLPDPIELVDAAEQLVDDGFVVLPYTSDDPVLARRLEQVGCAAVMPLGS
                     PIGSGLGIRNPHNIELIVERATVPVVLDAGLGTASDAALAMELGCDAVLLATAVTRAQH
                     PARMAAAMRHAVEAGRLARLAGRIPMRRYAQASSPFEGMVKSS"
ORIGIN
        1 tcccgcctca caggacgggt cttaaaggac gccttgtccc ccacaaggta gcaggaccgc
       61 tcccctgaac cgaacccctc ccggccacat catgcctggt gagagcggtc acacaccgcc
      121 gcgcgcccgc acgcgcgggg cgcgcgcgga aggggtcgcc gatgcccgca gggcggggcg
      181 tgcgggcctt cgcgtcgatc cggacgaccc ggatcgacac ctacggattc gaccgctttt
      241 ttccaatcgg cttgacctgg gggcgtcacc gttttaccgt cactgtccgt aaccatccct
      301 ggaggaggac ttccgggccg tgacggccgg gaggcccgac tccgcccggc accggaccca
      361 ccggcgccgg ggaatccgca acgacgacga gaagtgagcc tggggggccg cgaaatgccg
      421 tctgaatacg ctaaggctct cggcgcgcgc ctgcgcgcca tccgcaccca gcagggcctg
      481 tccctgcacg gtgtggagga gaagtcccgt ggccgctgga aggccgtcgt cgtgggttcg
      541 tacgagcggg gcgaccgcgc cgtcaccgtt cagaagctgg ccgagctcgc cgatttctac
      601 ggcgtgccgg tctccgagtt gctgcccggc ggagccgcgc cgagcccgct cgggccaacg
      661 cccaagctcg tcatcgacct tgagcgcctg cagcagcttc cgaaggacaa ggccggtccc
      721 ctcgcccgct acgccgcgac gatccagagc cagcggggcg actacaacgg aaaggtcctg
      781 tccatccggc aggaggacct gcgttctctt gccgtgatct acgacaagtc cccgaccgag
      841 ctcaccgagg agctcatcgg ctggggcgtg ctggaccccg aggcccgcag ggccgtggag
      901 tccttctaac acccgggtca cggcccccgg aagcctttcg ggaggccggg cggagaccct
      961 tgcgtcggac ggtccggcgg ccttcgtgcc gccgggccgt ccggcctttg tgccaccggc
     1021 tgggcgtcct agcgctgcgc gctggggcgt gttgacgcgg gctcatgcgc gtccgggtcc
     1081 agggcctcgg accgccgtgt cgcgcgccct cgccctcgtc cccgtcgtcc cggcgcggcc
     1141 agcgcgagcg ccagcacccc cgccatcgac gccgccgtga cggtgaagcc cgtcgtgtag
     1201 cccgtcccgc cgggatggcc gtggacggcc gaggcggtga ggatgaccgc gctgacctgc
     1261 gtcccgaggg acccgccgac cgtccgcaac agcgtgttca ccccggtcgc cacccccgtc
     1321 tgcgcgggct cgacggccgc gaccaccagg ttcgcgaccg ccgcataggc caaccccagc
     1381 ccgacccctc gtgccgtccc gccgacgtag agctcccaca tcgcgccatg ggccagcgcg
     1441 acgaacgcat accccgcgcc cgtgagcacg gcccccgcca tgaggacggc acgggacccg
     1501 acgcggtggt ggagccgtcc ggcggcgatc cccgcgagcg tcatccccac gctcgcggga
     1561 agctggagca tcgccgccgc cgtcgcgctg cccccgaacc ccgtcggacg cggagcctgc
     1621 accagcagcg ggaacagcac gccgcccgcc atcaggccat aaccggccag caacgacgcc
     1681 gcgttcgccg tccagacccc gcgcacgcgc atgagccgcg gatcgacgag cggctcgtcc
     1741 accctccgtt ccacgaccca ccagacggcc gccaggacca cggcggcgcc cgccagcccc
     1801 agcaccccgg cggacgtcca gccccacgac atgccctgcg tgagcgcggt cagcgccgcc
     1861 accatccacg ccgagaacag gcccgcgccc caccagtcga cgcccgcgcc gggccgtccg
     1921 ggcacctgcg ggacgagccg ccacgccagg accagccccg gcaccagccc gagcaccggc
     1981 atccacagca gccaccgcca ccccagcagg tcgatcaccg gcccggccac gcaccacgac
     2041 ggcgccccac ccagcccgag catggacgac atcaacccga ccgccgaggc cgtccgcgcc
     2101 ggcggcagga cgctccggat caccgtgtac gccagcggga acacgccccc gccgatcccg
     2161 gcgagcgccc gcccggccag cagtaccccc agagagggcg caatcgccgc cagaaccgtc
     2221 ccggccgtcg ccacgcccag aaccaccaac agcacccgcc gaggcccgta caggtcaccc
     2281 aggcgcccca cgacgggcgt cgagaccgcc gccgacagca tcatcgccgt cagcccccag
     2341 gccgcccccg ccgccgacgt gtgcagatcc cgctgcacca gcggcatcgc gggcgtcagc
     2401 accgccatcg agagcgagta cgccaccacc cccaagaacg ccaacaacgc cggcagtgtt
     2461 gactttgagc ccccggctcc gaggactcgc ctggcggctc gccctcggcc cggtgactcg
     2521 ggcgagcgcg gcatcgcttc gcgatcagcc gtgcgggggt tcgcctccgg cgtcaccccc
     2581 gcacggctgg tagcgcgctc gcgcgcggct cggccatccc cgcccattcg ccatatcgcc
     2641 acgcgaatat tgtcgtccgg caacaaacca tggcccacgc ttcataaacc acttaggcgc
     2701 tcaaacaacc cgcgacactt cacctcgcac cgacactccc cgtgaccacg tccggccatc
     2761 cgacgaggtc aggaccaaga tcactccccg agagaaggct cccgggcaag gtgacacgct
     2821 tcacacctca agaagacgtt tcacccccga aaggcaaggc cgatgacact cgcccaacac
     2881 cgtcgacgcg aagtgacact tcggcccact tcactcattt gacgaggtca ggcacgcaag
     2941 tccagcccac aactcccgcg cacacacgag ccgaagcccc tcccccgcta gagcacaagg
     3001 gccgggccgg gccgggaccg gggccaggcc gggaccgggc tgggaccggg accgggccaa
     3061 ggcagggcgg ggaccaggac cggggccggg gcagggcggg gccggggccg ggcggggacc
     3121 ggggccgggg cgggggcagg gcggggaccg gggccggggc ggggaccggg gcggggcagg
     3181 gcaggggcgg ggccgggaaa cggcgtcggg ctggggagcg tggccgggcg gggtgaggtg
     3241 gggagtggcg tcgggccgtc gcggcgcggt gaggatggcg ccgcgacggc ccgacgcgcc
     3301 ggccgtccca aggggcgcga cggccgggtc ggtgtcccgg catgagggcg cggacggggc
     3361 ggactggcgt ccgcgccctc atgccgggac gtaaggcccg gaggagcggc cccgcaacac
     3421 gcatcctccg ggagtctcag gcggcggcct cagccaccgc gcgagcgcgc caccagccgt
     3481 gcgggggtga cgccggaggc gaacccccgc acggatgatc gcgaagcgat gtcgcgctcg
     3541 cccgagtcac cgggccgcac ccgagccgcc aggcgagggc gcggagccgg gggctcaatc
     3601 aactcagctc gctcggttgg tgttggtggt cgggaggctc tgctggatgg ggactcccag
     3661 ggtgtcctcc acgagggtga cgaagatctc ggcgtcgtgg aggagttcgt cggcctcgcg
     3721 gggggtgacg gctcggggga ggcccgcttc ggcggcggcg cgcttgtcgg ctccggcggc
     3781 gaagtaggcg gcccactcgc gcagcgcggg gtcggcttcg gggagaagga cccagacgct
     3841 gcgggggcgg gcgcgccgcc tggtgaggtc gaggggctgg tgcgccgcca ggacggccgc
     3901 ggcggcgcgc agcgcggcca ggtgggcgct gacgtaccgg acggcgggcg tggtcgcctc
     3961 ggcggcctcg gcgagaccgg cgcgggcggc gtgcagctgg ccgacggcgg tgtgcgcggg
     4021 acggggcgcg ggcagcgcgc gggggcgctg ccgcggggcc tcgtgctggg cggcgcctgc
     4081 gacgttatgg gtggcggagc gggctccgcg ggtgagcgtg gtcatgagtc tgcctccttc
     4141 cggggcgtcg ggcatggccg ggcggagagc ttcccctctc tccgcccggc cgaggcgtcc
     4201 ccgccgtgtc cgcgcgctgg acacggcggg gacgtcgccc gtggcacggg ccgcgagtcc
     4261 cgcaccacgt cgaacataag ttcgacgcgt tcacagtaaa ccggttccgt gcccgttcgt
     4321 caatacgttc gaacgcgcat cgccacgcag agcgatcatg agactgatca cgcaggtcag
     4381 cgacgtggag tccactagaa caaacgggtc tgacaatccg gggtgcggtc agtcgcggta
     4441 gtcgtcggcc agccagtggg acaggtcgtc cggcgggggc gggacggcgg cggggagcag
     4501 ccgcaggacg gtccgcagcg cggccgaggt gtcgccggaa cgccaggtca ggcaccacgg
     4561 gacgagcgga accgggtcca ccagacggat cctgtgcagc tcggtcccct cggggagttc
     4621 gatgcccgcc tcccccagcg cgaccgcgtg ctcctcgcgc gcgacgagct ctccgtagtg
     4681 ccacaggccg acggcgggtt cgacgaaccg gatcgggatg ccgaagcggc ccgcgaggcg
     4741 ggtgaggaac gcccgcgcct cggacgcgac cgggtcgggc atgacgacgc cgatgtcgcg
     4801 cagctcgtcc ggacgcatcg cgtcgcgccc ggcgagcgga tggtccgggc cgacgaacgc
     4861 ctgcatcggc accagctgga cgacccggga cgccagcccg gacggccagc gtcccggaag
     4921 gtccctggcc tggccgaacg cggcgtcgat ctcgccagac agcagcgcgg ggacggcctg
     4981 ctcgaagccc tgccgcatgc tgacctcgac gcgcaggcgg gattcgcggt cgagcagccc
     5041 ccggacgagc gtcatcgggc tgaagcgctg gtcgtagacg tccacacgga ggcgcggcgg
     5101 ctcaccccgg acggccgcca tgaccgagtc gatggcgttg agcgtctctc gtgcgcgcgg
     5161 gaggacgcgg cgtccggcgt cggtgagctc cacgcggcgg gtggtgcgtt cgaacagcgg
     5221 cgcgccgagg acggactcca gccgccggac gcgctgggac agcgcctgct gggtgaggaa
     5281 caggcgctgt gcggcccgtc cgaagtgcat ctcctcggcg gcggcgacga aggcccgcag
     5341 tccgggaacg tccacatcca caggtcaagc gtgggattga caagcgcgcg ttgtcaaagc
     5401 gccggaagtc ttgttggacg ccgcccggcg cgcgccggtt atctcgacgg catgaccaac
     5461 ccaccgcacc agctctccga ggacgtcttc cagcgcctgc tcagggagcg gatcgtgttc
     5521 ctcggccagg aggtcgacga cgcgatcgcc aaccgtctct gcgccgagat ccttctgctg
     5581 tcggctgaag acccgcagcg cgacatccag ctgttcatca actccccggg cgggtccgtg
     5641 accgccggga tggccatcta cgacatcatg cagttcgtcc cgaacgacgt ggcgacgctg
     5701 tcgctcgggt tcaccgcgtc catggggcag ttcctgctgt gcgcgggcgc gccgggcaag
     5761 cggtacgcgc tgccgcacgc gcggatcctc atgcaccagc cgtccggcgg gatcggcggg
     5821 acggcgacgg acatccgcat ccagaccgag aacatgatcg ccaccaagcg gctgatgcag
     5881 cggctcatcg cctcccacac cgggcagtcc gccgagcgga tcgaggccga ctccgaccgg
     5941 gaccgcttct tcaccgccga ggaggcccgc gcctacggct tcgtcgacca cgtgatcgac
     6001 aacgcccgcg ccctcccggc ggccgcgtga acaacccgat accgggagcc cgggcgacgc
     6061 cttagggtgc cgtccatgca ccccaacgcc gagcgcgtcg ccggtgtcct gcgcgagcag
     6121 ggcgcggacg gcgagatcat cgaactgccc gactccgccc gcaccgccca ggccgccgcc
     6181 gaccagctcg gctgcgaggt cggcgcgatc gccaacagcc tcgtgttcga cgccgacggc
     6241 gcgccgctgc tcgtcctgac cagcggcgcg cacaaggtgg acacggcgcg cgtcgccgcg
     6301 ctggtcggcg cggggagggt ccgccgggcg acgcccgagt tcgtccggga gcacaccggc
     6361 cagcccatcg gcggggtggc gccggtcggg caccccgccc cgatccgtac cctcgtggac
     6421 gtctggctgg acaagcacga gcgggtctgg gcggcgggcg ggcacccgca caccgtcttc
     6481 ccgacctcgt acgaggaact gctgcgcgtc accgggggcg acgcggccga ggtgggagag
     6541 taggggcatg gagatctggc acaacccgcg ctgctccaag agccgcgcgg ccaaggccgc
     6601 gctggacgag gcgggcgtcg cctacaccga gcgccgctac ctggacgagc cgccgacggc
     6661 cgccgagttc gaccggacgc tcaccgcgat cggcgccgag ccctgggagg tcgcccggct
     6721 gggcgaggcg gtcgccaagg agctcgacct gaagaacctg ccgcacgacc gggacaggtg
     6781 gatcgaggtc atggtcgcga acccggtgct catccagcgt ccgatcatcg tcacggacgg
     6841 atcggccgtc gtggcgcgcg acgaggagtc ggtccagcgc gccctcggcg acgcctgacc
     6901 acccgacgtc ccgacgccgg acggcccgca cgccgcgcgc gtcccccgcg tgcgcgggcg
     6961 cggcgcgttg tgcgccggga acagcaggcc ctgccccgcg cgcgcccctg cgtgcgcggg
     7021 cgcggcctga ccgtgaccgt ccggcactcg acatcgcctg ttgcgagtgt gattctgggg
     7081 aaccgacccc cggcgcgacc ggcgcgacgg actggagcag cacccggagg ggcgatgacc
     7141 gctgagatgc gcaccggccc ggccagccgc gacggcgact tccggggcat cgatccaccc
     7201 gcgctggacc agctgctccg gcaggtccag caggcgaaca ccgcgatccg gggctggctg
     7261 gcggggcacc gtccgccgcc cggggtctcg gcgtcggggt accggcaggc cgaggcggtc
     7321 gggcagtggg cgtccgacca gatcggaatg ctgtcccggc ggtacaactt cgcgatcacc
     7381 catccggacg acggcggcgg cgtgcacgtc ccaccctccc ccgcgccgag ccccggcccg
     7441 tccggcggga gcgggggcgg aggaggcggc gggacgtccg gtccgggcaa ggtcactccg
     7501 ccgcgcacac acaagcgccc gcaccggacg accccgaacg gcgcgggcga cctcggcggg
     7561 ttcacgaccc cggaggccgc cgccagggcc gcccgcaagg acgcgctcgc catcgacgac
     7621 gcgatcaagc accaccggcc cgtcccggcg gagacctgga agcacctgac cgagcacgcg
     7681 ggcgacccgg actacacgcg ctcgctctac gagcggctcg gcccgtccgg ggcggcggag
     7741 ctgatcaagg cggcgcacgg gaacccggcg cgcctcaagg cggtcgagcg gtccctcggc
     7801 gtcgcgagcc accacgtcac gatgaacgcc cgctggctgg acgccctgct ggacgagtcg
     7861 gaccgcctcg gcgaccacac gtccgccgtc cacgtcctga cgacggccca cacgagcgcc
     7921 cgcacccgcg acgcgctcac caagctcggc ctcctccacc aggggtcgcc tcacgcgccg
     7981 caccacacgc cgcaaccgcc gcgccatccg gtccagccgc ccgcgacatc cgcagggccc
     8041 gcgttcgaga cggcgacgct ggtgtccgac accaaggctc ccgggacgac gatccccgaa
     8101 gcgaaggtcc ccgagacgaa gggctgcccg acatgagccc gcccccgccg cccgcgagcc
     8161 tccccgctcc cctggagggc gcggcagcgg cccagctggc cccgcacgag aagccgaacc
     8221 ccgagtaccg gcagatctac caggcgtaca gcgacgccta cggcagcatc gacgcgctcc
     8281 gcaacgcgct ggacgcgccc gtccggacgc tgaacggcac ggacgcgtgg atcggcccgg
     8341 agtcgcgcgc ctggggcggc cagctggaga cccagcgggc cgcgctgcgg aaggcggccg
     8401 accagatcct gtgggacatc tacaaccggc tcgcggggac gcagcggacc atcgtccggg
     8461 tctaggctct ctcggcgtga ggaagaggga gccgaagctg cgtcgactcg acgaatccgc
     8521 gttcctgcgc cgcctggacc cgatccttca ggtctacgcc gccgcgatgc gcccgcccgg
     8581 ggagcagctg cccggacggt actcgatcat gcagcggcac accacgtacc cgcggttccg
     8641 cgcgtacgtg ctggagcagc cgcgtccggt gcccgggata ccggggagcg tgcgggggtt
     8701 cgcctacggc ttccacggcg aggccgggca gtggtggcac gacgtggtgc ggcgggcgct
     8761 ggtcgagcgg gacggccccg agcacgccga ctactggctg gacgacgcgt tcgaggtcgc
     8821 cgagctgcac gtccaccccg aagcgcaggg gtacgggcat ggccgggcgc tgctgaacgc
     8881 gctgtgcgag ggcaggcggg agcggacggt cgtgctctcc acgctcgacc tggaccgcga
     8941 gtcgcccgcc cgccggctct accgctccgt cgggctgcgg gacctgctga ccgacttcga
     9001 cttccccggc ggcgggccgc cctacgccgt gatgggcggg acgctgcccc tggccccgta
     9061 cccggcgtcc tccagcagct cgtagacctc gcgggtcgcg gtcgagcggt tgaaggtgat
     9121 gaagtggatg ccgggcgcgc cctggtcgag caggtcccgg cagagctcgg cggcgtgctc
     9181 gatgccgagc cgccggacgg cctccgggtc atcccggacg gcgtcgaacc gctcgcggac
     9241 ctccggcggg aacggcgcgc cggacagctg ctcggacttc tcgatcgtgg tgatccgggt
     9301 caccggcatg atgcccggga tgatcggcac gtcgcagccc tcgcccgcga cccggtcgcg
     9361 cagccggaag tagtcgtccg cgcggaagaa catctgggtg atcgcgtagt cggcgcccgc
     9421 gcggcacttc tcgacgaaga accgggtgtc gctctcgatg tcgcgggagc gcgggtgctt
     9481 gtaggggaac gcggcgacgc cgacgcagaa gtccccgtac gagcggatca tccggaccag
     9541 gtcggaggcg tactccaggc cctccgggtg cttgacccac tccgccgacg ggtcgcccgg
     9601 cgggtcgccg cgcagcgcca ggatgttgcg gacgcccgcg gacgcgaacc gtccgatcag
     9661 gtgccgcagc tcggcctggg agtggtcgac ggccgtgaag tgcgccacgg gcgtcatggt
     9721 cgtctcggtg gcgatccgct cgaccacgtc cacggtgttg tcgcgggtgc tgccgcccgc
     9781 cccgtaggtg accgacacga aggtcgggtt cagcggctcc agctcccgga tggtgcgcca
     9841 cagcgtccgg gccgcctcgg cggtcttcgg cggcatgaac tcgaaggaga acgacggttc
     9901 tccggtggcg agcagctcgc ggatcgtcgg agcgcgatcg gggttcgggc gtcgcatccc
     9961 gcaatcctat cgacccggtc cgaaaagata cgatctcggc atgtccagca gttcgtccgg
    10021 tccctcgccc gtcagcaccg ccaccggcca gttccgcaag gaggtcgacg aggcgctgca
    10081 cgccttcgtc gaccgccagg cccccggtct cctcgcgatc agcgaggacc tgcggcccat
    10141 gatcaccgcc ctctcggccc tgctgtcggg cggtaagcgg ctgcgcccgg cgttctgctt
    10201 ctggggctgg cgggccgccg gcggcctgga cggcccggag atcgcggcgg cggcggcgtc
    10261 cctggagctg ctgcaggcca gcgccctggt ccacgacgac gtgatggacg ccagcgacac
    10321 ccgccggggc cagccgtcgg tgcaccggcg gttcgaggcg ctgcacgccg agcgcggctg
    10381 gcgcgggccc gcggacacct tcggcgaggg cgcggcgatc ctgctcggcg acctgctgct
    10441 ggcctggtcg ggcgagatgt tcgagaccag cggcctgtcg gaggagcgcc gcgcccgcgg
    10501 acgcggcgtc tacgacgtga tgcgcaccga ggtcatgtgc ggccagtacc tcgacatgct
    10561 ggagagcacg cgcgcgggcg ggacggtcga gtcggcgctg cgggtggtgg acttcaagtc
    10621 ggccaagtac acgatcgagc gtccgctgca cctgggcgcg tcgctggccg ggggctcgga
    10681 ggagctgacg gcggcgctgc gcgcgtacgg acggccgctc ggcatggcct tccagctgcg
    10741 ggacgacgtg ctcggcgtgt tcggcgaccc gtcccagacc ggcaagcccg ccggggacga
    10801 cctgcgcgag ggcaagcgga ccgtcctggt ggcgctcacc ctggagcgcg ccacgccgga
    10861 ccaggccgcc acggtcgacc ggctgctcgg cgacccggag ctgtccgggc tcggggtggc
    10921 cgacctgcgg gagatcatca ccgggacggg cggcctggcc gcctgcgagg agatgatcgt
    10981 ccggttcgcg gccgaggcgc gcgaggcgct ggccgccgcg ccggtgaccg gtgaggcccg
    11041 cgaggccctc acggagctgg cggtcgccgc gaccgcgcgc tccttctgag gcctctgagg
    11101 ctttaagacg ggttgtcaac agcctgacac gatgtggcca atgcggcggg acgggctagc
    11161 actgtcccag tgatcggtgg cagaaagtac ggcatggcct ccgacacccc gcccgccgag
    11221 gacatcccgt ccgccgagca cgccgcgccc gccgaacacg ccccgcccgc ccagaacgcc
    11281 acgtccgccg acgctccgcg catcgcgccg ctgccgtccg gggagtggga cgacacgctg
    11341 cgcgccgtcg tcgccgccac cggcccgctg aacgtcttca cgacgctcgc ccggcatccg
    11401 gcgctgttca cggcctggat cgggttcggg tccaagctgc tgttcgaggg cacgctggac
    11461 ggacgcgtcc gggagatcgc gatcctgcgc gtcgcgcacc agcgctcgtg cgcgtacgag
    11521 tgggcgcacc acgtcccgat cgcgcagctg gccgggctgg acgagacgga gatcgaggcg
    11581 ctgcggggag cgccggacga tcatccctgg tcggcggacg accgggcggt gatcgacgcg
    11641 gcggacgagc tggacgccac ctcgaccgtc tcggacgcga cgtgggcggc gctggcgaag
    11701 cggttcgacg cggcccggct gatcgagctg gtcatgctca tcgggcagta ccacatggtc
    11761 gccttcgcgc tgaacgcgct gcgcgtccag atcgaggacg accactgatg cgcgcgcgca
    11821 cgagccggac ggcgggcgcg acgcggacgc ggacgcggac cggccgggtg tggggtgcag
    11881 gggccctcgc atccgcgctg gtcgtgtcgg tctgggccgt ccagtcggcg gaggcgcagc
    11941 cgggacgggc cgccaaggcg gcggcgtcca cgcgctgcgg cgacccggcg acgcggccct
    12001 ggtgcaggcg gaccctgacg gcggaccagc gggtggctct gctgctgccg aagatgaccg
    12061 ccgacgagaa gatctcgctc ctcgcgtcgg acgacccgct gggcggcccg ctcggcggct
    12121 tctccgagaa cgcgcacgcc gacaccagcg ggggcatcac gcggctcggc atcccgccgg
    12181 tctacatggc ggacggcccg gcgggcgtcc ggcagggcaa ggcgaccgcg cttcccgcgc
    12241 cgatcacggt cgcggcggcg ttcgacccga acgcggcccg cgactacggc tcgaccgtgg
    12301 cgtgggaggc ccggcaccgc ggcaacgacc tgatcttcgg cccgaccgtg gacgtcctgc
    12361 gcagcccgcg cgacggacgc tcgttcgagg gcttcggcga ggatccgttc ctgtccgcgg
    12421 cgaccgggac gtcctggatc aagggcgccc aggcgcaggg cgtcatgacg tcggtcaagc
    12481 acatggcggt ctacacgcag gagaccgacc ggatggcgct gaagatgaag gtcgacccgc
    12541 gcacgctgcg ggagatctac ctgccgccgt tcgaggccgc ggtgaagacg gggaacgcgg
    12601 cgaccgtgat gtgcgggttc gggcagctga acggccgctg ggcctgccag gacgacgcgt
    12661 cgctgaacaa gatcctgcgc agggagtggg gcttcaaggg gttcgtggcg tccgaccaca
    12721 ccgccgcgca ggacacgccc ggcgcggcca acggcggtct cgacctcgaa ctcccctacg
    12781 gctaccggta caacaacctc gccctcaagg ccgcgctcgc ccagaagcag gtcacctgga
    12841 cgaccgtgga cgcgcacgcg cgggcgatcc tgcggacgat gttcgcgttc ggcctgttcg
    12901 accgtccggc ctacgcgaac gacctgacca agatcagccg ggcgggcagc gaggcggcgg
    12961 cgcagcggat cgaggagaac ggcatcacgc tgctcaagaa cggcggcgtc ctgcccctga
    13021 aggccccgaa gaaaatcgcg ctgatcggcg gggccgccga cgccaacccg agcgggttcg
    13081 gatcggcgca ggtccagccg ttcacgtccg tgacgcctcg tcagggcatc agcagacgcg
    13141 cgggcgcggg agccgcgatc acctacacca gcggacggaa ccagggcgac gccgcgaagg
    13201 ccgcccggca cgccgacgtc gcgatcgtgt tcgcgaccga cagcgagggc gagttcttcg
    13261 accggtcctg cctgacgctg aactgcggcg acccgctcaa gggcgaccag gacgggctga
    13321 tctcggccgt cgcggacgcc aacccgaaca cggtcgtcgt cctggagacc ggcggcccgg
    13381 tgctcacccc gtgggcgggc aaggtcaagg ggatcgtcga agcctggtac ccgggcgcgc
    13441 gcggtggcga cgccctcgcg cgcgtcctgt acggggacgt cgacccaggc ggacggctgc
    13501 cgttcacctt ccccgccgcc gagggcgacg cgcccacggc agggaacccg gcgcagttcc
    13561 ccggtgtgga caagacggtc acgttctccg agggcgtcct ggtcggatac cggcactacg
    13621 acgccaaggg catcgcgccg cgattcccgt tcggcttcgg gctgtcctac acgacgttcc
    13681 ggtacagcgg cctcaaggtc acgcccacct cggtgcgcgt gacggtcacc aacaccggct
    13741 cgcggacggg cacggcggtc ccgcagctct acctcggcct gcccgcgccg aacgtcacga
    13801 cgccgcagcc gccgcgccaa ctcaagggct tccagaagct cacgctcgcg cccggggcga
    13861 gctcgaccgt gacgttcccc ctcaccgacc ggtcgctggc cttctgggac accccctccg
    13921 gcgcctggaa ggtcgcgccc ggctgctatc gcgtccagct gggaggttcg tccagggatg
    13981 cggctctgac cgggagtttc acgcgcggcg gaggcgcctg ccgggcgtaa aagatcaagg
    14041 gtcccgcccc acgccggacc ggcacagggt acaaaagagg gaaacttcca ctcgtcctcc
    14101 cccgccgagt tcggagcccc cgttgccgtc atcctcctcc cccgggagca tgctggaccc
    14161 ctcgtccagc cgtcccggcc tgcccctcgg cccggacgac ccgcgccgcc tcggcggtta
    14221 ccggctcgtc cgacgcctgg gcgagggcgg ccagggcgtc gtctacctcg ccgtgccccg
    14281 ggactccggc ggcgcgcacg tcgcggtgaa gctgctgcgc ggcggggccg ccgcgacgcc
    14341 gcgggcccgc agccggttcg tcaaggaggc ggacgccgcc gccgagatca ccaaccggca
    14401 cgtcgcgcgc gtgctggagg cggacgtgac cggcgaccgt ccctacatcg tctccgagtt
    14461 cgtggacggc ccgtccctgc aggagtcggt cgaggaggac ggcccgctca cccccggacg
    14521 gctccgccac gtcgcgctgc gcacggccgc cgcgctcgcc gcgatccacc gcgcgggcgt
    14581 ggtgcaccgc gacttcaagc cgggcaacgt cctgctcggc ccggacggcc cgaaggtgat
    14641 cgacttcggc gtcgcccaga ccgccgacgc caccccggtc accacccacg gcgcggtcgg
    14701 cacccccgcc tacatggccc ccgagcagat cgaggacgag ccggtcggcc cgcccgccga
    14761 cgtcttcgcc tgggccgcga cggtggtgtt cgccgcgacc ggccgtccgc cgttcggcgg
    14821 cggcgcgagc gcggcggtca tgcgccgcat cgtcacccgc ccgccggacc tcggcgacct
    14881 ggacggcgag ctgcgcgacc tggtggagca ctgcctggac aagaacccgg cggcgcggcc
    14941 cacggcgcgg caggtcgtcc gggcgctgcg ggacggcgag gccacggctc cgaagccgcg
    15001 gccgaagaag atcccccgct accggtggcg gatgatgctc gccctcgccg ccgtcgtcac
    15061 ggcgggcttc gccctgggca tcctgctcta gagcgtcgcg aagacggcgc gtgcggcggc
    15121 gtgcgaaagg ccccgccgga cggcggggcg cttcgcgtgg cgggccggga tcaggccgtc
    15181 gccgccttcg ggcggcggag caggccgatc gccgtgccga ggagccacca gctgaacacc
    15241 gcgcccatga gcgccgtggt gccccagccg ttggcggcgt agaagtgcgc gggcgtgttc
    15301 ccgaagaaca gggacggcat gaaggccagg ttgaccagcg ccaggccgca ggtgaacagg
    15361 cccgcccagc gcggcaggac ggacgtccgg aggatggcgt agccgaccga tcccaggaac
    15421 atcgcgagga gcatccggcc gatcgtgccg tacaggatgt aggtgccgtc gaccgtgacg
    15481 gtggggtcga tcgggtggtc ggacgcgatc accgcgcccg cctccagacc cgacgagacg
    15541 agggtgacga cgccgtaggc gaggcccgcg ccgccggcga agcgcccgat ccaggcgctc
    15601 tccggggcgg cctggatgat cagctcgcgg aaggacatcg cgaaggcgag gacgaacccg
    15661 agcccgagga cgccgatcag caaccggctc aggacgttcg aggcgggcgg cgcgccggag
    15721 tagacgaagt agagcgggac ctccaggagg agggccgccg cggcggcgag tccggcggtt
    15781 ccggtgaggc ggcgggcgag cggcaggttc atcgcgtttc ccatcaacgt gtgtgtggtg
    15841 gaacgctttg aatccttcgc cttccagcag ccccggccag tgggcctggg ggccggatcg
    15901 acggggacct gaccccccgg tgcccggtgg acctcggccc agcggctcac cagtgcggcg
    15961 gacgctcctc gaggaagcgc gcgtcgtcgt ctccgccgtc gcgccactcg ccccagcccg
    16021 cgtcggtgtc gtcgccggtc tggtcgggca ggacgggcag gtcctcgtcc gccaggtcca
    16081 ccacgcggtc gtcgtctggt gaaacgctca tgcatccatt gtcggtcacg ccggaggcca
    16141 ctggtgacca cccggcgtcc gggacgtggc ggcgtgttgt catctcccgg acgaacaccc
    16201 gtcaggggcg tccgccggga cgcctcggag gtcaggcgtc ggcgcggtgg aggcggcggg
    16261 cgagctcggc ggcggcggcg cccgggtcgt cggcctcggt gagggcccgg acgaccacga
    16321 cgcgctccgc gcccgtggcg aggacctggt cgaggttgcc gaggtcgatg ccgccgatcg
    16381 cgaaccaggg gcgcgccggg ttgcgtccgg cggcgtactc gagcagcggc aggccgggcg
    16441 cgtggcggcc gggcttggtc ggggtgggcc agacggggcc gcagcagaag tagtccacac
    16501 cgggctcggc ggcggcgtcc gcggcctgct cgtccgaatg cgtcgagcgg ccgatcagga
    16561 cgtcctggcc gacgatcgcg cgggcggccg ggacgggcag gtcgtcctgc ccgaggtgca
    16621 ggacgtcggc ctggacggcg tgcgcgacgt cggcgcggtc gttgaccgcg agcagcgcgt
    16681 cgtgccggtc gcaggcgtcc cggaacaccc gcaggtgctc gatctcctgc cgggcctcca
    16741 ggcccttctg ccgcagctgg acgatgtcga ccccgttcgc gagcaccgcg tcgaggaact
    16801 ccggcaggtc gccccgctcc tcccgggcgt ccgtgcagag gtagaggcgc gcgcggccga
    16861 gccgggcgcg cagccggacg gcgcggtcgg agggcaggtg cctggacacg gtgggcgggg
    16921 tccttccgga gaacagacgg gggccacgcg cgcgggggtc cgcgcacgtg acccgcatca
    16981 tttcacgtgc tttgcggcga actcgggcgg gccgtccggt acgtccctcc gccaggggtg
    17041 gaccggacgg cgcggccggt tcgccttggg tacggcctag aaggcgagcg cctgggcccg
    17101 ccgccggacc tcggtgcccc ggttctcggc cagcgcctgc accggcgtgc cgggcagcgt
    17161 gtcgtcggcg gtgaagagcc agcggagcgt ctccacgtcg tcgaacccgg cgtccttcag
    17221 gagtgtcagc gttcccggca ggcccttgat cacctggccg tcggcgatga acgccgccgg
    17281 caccatcggg tggccgtccc ggcggacggc cagcagcttg cgctccgcca gcagctgctt
    17341 gatccggttg aacttgatgt cgaggcgctc ggacacctcc cgaaggccga tccactcgcc
    17401 caccagggcg tcggtacggg ggtcgaggtc actctctacg gttgcgtgcg tctgcgtcac
    17461 gcccccttgc taccacgccc ccagagcact caaacccgcc caggacctcc ggagattctt
    17521 ccgttgatct ctcaccgttg gtcaggactt caccgactga cgcaccggaa tgcccggatc
    17581 gcccagcagt acggggtcca cgggcgtccc ggcggcgatg atccgcttcg cctggacgag
    17641 gtcgcgcgga cggtccaccg tcaagatcgc ttcaagccgg tcaccggtga tccacgccac
    17701 ggcccaggcc ccgtcctcgg gcgagccgcg gcggatcatc cgctcggccc cggcgtggtg
    17761 acccgcgtac tggacgaacc ggtcgaactg ctcggaccag aagtaggggg ccacgtcgta
    17821 gaccgcgtcc tggccgagca gcgtcgcggc ggcggtctcg ggcgcgttca gcgcggtgtc
    17881 ccagtgctcg atgagcagcc tgcggccgta ccggttcgac caccaggcgg cgcagtcccc
    17941 gaccgcgacc acgtcgtccc ggacgacgcc gtccaccgag gcgcgcaggg acgcgtcggt
    18001 cagcacgccc cgctcgacgt cgaggcccga gccgtccagc caggccacct cgggacggac
    18061 gccgacgccg gtcacgacca ggtcggccgg gatgtgcccg cctccggcga gtgcgagacc
    18121 gtccggctcg accgaggcga ccttcacgcc cgtccgcagc tcgacgcccg cctcggcgta
    18181 ccagggggcg gtgagcgcgc cgagctccgg cccgagcgcg ttcgccagcg gcgcgtcggc
    18241 ggcctccacg accgtcacgg cgcaaccgtc cttggcggcc gtggtcgcga cctccgcgcc
    18301 gatccagccc gccccgacga tcaccacgcg ggcgccgggg gccagccccg cccggacctc
    18361 cagcgcgtcg tccagggtgc ggatgacgtg ctgcgggccg tcgcccggca tccggaccgg
    18421 cgtcgcgccg gtcgcgatca ccaggccgtc gaagtccagg tcaccggccg tcgtggcgag
    18481 cgtcccgccg cgtccggggc gcagccgcag ggcggtcgcg cgctcgcccg ccagcacccg
    18541 gacgtccagg gccgcgaggt cggtgtccag ggccgggaag tcggtctcgc ccttgaggac
    18601 ggccttcgtc agcggcgggc ggtcgtacgg ccggtgccgc tccgcgccca ccatcgtcag
    18661 cgcgccctcg tacccgtgct tgcggagcgc ctcggccgcg cgcacgcccg cgagcccgcc
    18721 gcccaccacc atcacccggt ccatgcccgc aggctagccg gtgtccgatt cgtcgtaggc
    18781 taggaggcgg aagtgcgcgg gagcccggcc tgaaccgggc tgagagggcg gctggacggc
    18841 cgccgaccgc ctgaacctga tccgggtcat gccggcgaag ggagccgccc gtgaacgtcg
    18901 tcatcatcgg agccggggtc gtcggcctcg gcgcggcttg gcgctgcgcg gcgcgcggcg
    18961 cggacgtcac cctggtcgac ccggagccct cgagcggcgc gtccggcgtc gctgccggga
    19021 tgctgacgcc ggtcagcgaa ctcgactacg gcgaggagcc gctgctcagg ctgggcgtgg
    19081 cgtcccgcaa ccggtacccg tcgttcgtcg ccgagctcga ggagctgacc ggccacgaca
    19141 ccgggcaccg caccgacggc ctgctcgagg tcgccttcga cgccgacgac ctgcgcgtcc
    19201 tggaggaggt gaagcgcttc caggaggccc tgggggtgcc caccgaggtc ctcggccggc
    19261 gcgagtgccg caggctcgag ccgatgctcg ccccgaccgt ccgcggcggc ctgtacgcgc
    19321 ccgaggacgg ctcgatcgac ccgcggcggc tcaccccggc gctgctcgcc gccgccgaga
    19381 agctcggcgc gcggctcgtc cggcggcggg ccgccgaggt gatcgtgcgc ggcggcgcgg
    19441 ccgtcggcgt ccggctggac gacggcgaag agctgcccgc cgaccgggtg ctgctcgcgg
    19501 ccgggccgtg gtcgggcgac atcggcggga tcccgccggg cgtcgtgccg accgtccggc
    19561 cggtgaaggg ccaggtcctg cggctgcgca cgcccgtccc gttcctgcgc aggacggtcc
    19621 ggggcgtggt gcgcggctcg tccgtctacc tcgtgccgcg cgcggacggc gagatcgtcg
    19681 tcggcgcgac gcaggaggag ctcggcttcg acacccgggt gaccgcgggc ggcctgtggg
    19741 agctgctgcg ggacgcccgc gagctggtgc ccggcatcac cgagctggac ttcgccgagg
    19801 tcaccgcggg cctgcgtccc ggctcgccgg acaacgcgcc ggtgctcggg ccgtccgcgc
    19861 tgccgggcct ggtgctcggc gtcgggcact accgcaacgg gatcctgctc gccccggtca
    19921 gcgccgacgc gctgagcgcc gccctgctgg acggcgagct ccccgaggtg gcgcgcccct
    19981 tctcccccga ccgcttctcc cccggacgcc cccaggaagg cacatgaaga tcattgtgaa
    20041 cggcgagccg cgcgacctcc ccgaggacgc cagcgtggcc gacgcggtcg ccacggtcac
    20101 cgaggccccg aacggggtgg ccgcggcgct gaacgacgag gtggtgtcgc ggtccgcgtg
    20161 gaccgcgacg aggctgaccg aggcggaccg gctggaagtc ctgaccgccg tgcagggagg
    20221 atgaccgtgg ttccgctcac cgaagggcat gaccccctgg tcatcgcggg cgaggagttc
    20281 gggtcccggc tgatcatggg caccggcggc gcgccgagca tgagcgtgct gggcgaggcg
    20341 ctcgccgcgt ccgggacgga gctcaccacc gtcgcgatgc ggcgggtgga cccgtcctcc
    20401 cgcggctcgg tcctggacgt cctgcgcgag cacggcatcc gggtgctgcc gaacaccgcg
    20461 ggctgcttca ccgcgggcga ggccgtcctg accgccaagc tcgcgcgcga ggcgctcggg
    20521 acgaactggg tgaagctcga ggtcatcgcc gacgagcaca ccctgctgcc ggacccgatc
    20581 gagctcgtgg acgccgccga gcagctcgtg gacgacggat tcgtcgtgct cccctacacc
    20641 agcgacgacc cggtcctggc ccgccgcctc gagcaggtcg gctgcgccgc ggtgatgccg
    20701 ctgggctcgc cgatcgggtc ggggctcggc atccgcaacc cgcacaacat cgagctgatc
    20761 gtggagcggg cgaccgtccc ggtggtcctg gacgccgggc tgggcacggc ctcggacgcg
    20821 gcgctcgcga tggagctcgg ctgcgacgcg gtactgctgg ccacggccgt gacacgggct
    20881 cagcacccgg cgaggatggc cgccgcgatg cggcacgccg tcgaggccgg acggctcgcc
    20941 cggctggccg ggcgcatccc gatgcgccgg tacgcccagg cctcgtcgcc cttcgagggg
    21001 atggttaagt cgtcctaact agtgtttcgt agtagtaatc actggacctg aacggtcgtc
    21061 cggcggcaca ctggggccgg aatcacggc
//
