LOCUS       NZ_KI911538            23948 bp    DNA     linear   CON 21-OCT-2024
DEFINITION  Nocardiopsis sp. CNT312 B042DRAFT_scaffold_3.4, whole genome shotgun
            sequence.
ACCESSION   NZ_KI911538
VERSION     NZ_KI911538.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nocardiopsis sp. CNT312
  ORGANISM  Nocardiopsis sp. CNT312
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsidaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 268603)
  AUTHORS   Jensen,P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R41043
            investigation_type                :: bacteria_archaea
            project_name                      :: Nocardiopsis sp. CNT312
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi14643
            Funding Program                   :: DOE-CSP-ICBG 2011
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000515115.1-RS_2024_10_21
            Annotation Date                   :: 10/21/2024 21:26:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,296
            CDSs (total)                      :: 4,234
            Genes (coding)                    :: 4,144
            CDSs (with protein)               :: 4,144
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 23 of 90
            Pseudo Genes (incomplete)         :: 74 of 90
            Pseudo Genes (internal stop)      :: 5 of 90
            Pseudo Genes (multiple problems)  :: 12 of 90
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:21:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 23948
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KI911538.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 407425
            Source DNA and Organism available from Paul  Jensen
            (pjensen@ucsd.edu)
            Source DNA available from Paul  Jensen (pjensen@ucsd.edu)
            Organism available from Paul  Jensen (pjensen@ucsd.edu)
            Contacts: Paul  Jensen (pjensen@ucsd.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23948
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..23948
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23948
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:3948](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <1..3948
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            <1..3948
                     /locus_tag="B042_RS24005"
     CDS             <1..3948
                     /NRPS_PKS="Domain: Condensation_LCL (0-294). E-value:
                     9.5e-112. Score: 364.8. Matches aSDomain:
                     nrpspksdomains_B042_RS24005_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (465-863). E-value:
                     1.6e-102. Score: 335.1. Matches aSDomain:
                     nrpspksdomains_B042_RS24005_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1032). E-value: 1.4e-27. Score:
                     87.7. Matches aSDomain: nrpspksdomains_B042_RS24005_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1054-1283). E-value:
                     3.7e-39. Score: 127.4. Matches aSDomain:
                     nrpspksdomains_B042_RS24005_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="B042_RS24005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_036555749.1"
                     /sec_met_domain="Condensation (E-value: 5.9e-69, bitscore:
                     226.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.7e-109, bitscore:
                     357.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-16, bitscore:
                     55.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 5.8e-32, bitscore:
                     105.7, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YAQRRLWFLDRVEGPSATYNIPVVLRLRGALDAGALEAALGDVVE
                     RHEALRTVFPSHEGDPHQRVLSCEEARPVLARVGTGAADTADHVARMVRHTFDLERDVP
                     VRAWLLCESEREHVLVLVVHHIAGDGWSMGPLLRDLGRAYRDRSRGAVPDWEPLEIQYA
                     DYALWQRGLLENDADGTPLDVQTEFWKKALEGVPEALDLPADRPRPAVASYRGEVLTFD
                     VPADVHRRLAEVAADHDATLFMAVQAALAVLLDRMGAGSDVPLGTPVAGRADTALEDLV
                     GFFVNTLVLRTDTSGNPGFGALLERVKEADLAAFAHQDLPFERLVEAVNPARSTAHHPL
                     FQVMLTLQNDAGASLGLPGLDVAEEPCATGMAKFDLTFVLRERRGPDGAPAGLDGGLEY
                     ATDLFDAESAALLAARLCRLLDAASAAPATGVRDLPVLTEEEYTHAVEEYNGTAVTAPP
                     RALVHELFEDRVNETPDAVALVSGDESLTYAELDTRANRLAHHLIALGVEPESAVAVLM
                     DRSVHQMVATLAVVKCGAAYVPLAASFPASRVRTIMAETGARALLTDSGARDGVVVAEA
                     GRGTPVAVVDALPADGPGRSPGVRVGDLALLYVMFTSGSTGRPKGVAVDHRNVVGLALD
                     RCWDGDAHRRVMVHSAYGFDASTYEMWVPLLRGSTLVLAPRTDGDARVLADTVRDGGVT
                     AAYFTTGLFNVMADECVEALALLREVWFSGDVASPGALQRVLDHCPDTAVVHGYGPTET
                     TVWSSYQAFGTGERRLDEVHLGTPMDDTTMYVLDDRLRPVPPGATGELYVGGAHVARGY
                     VGRPDLTAERFVADPLGEPGRRMYRTGDLVRWTRQGRIRFIGRIDGQIKIRGFRIEPAE
                     VEAVLGSRPGVSQCAVVVREDRPGDKRLVAYVVLDPGHGLDRAELRRSMGETLPDYMVP
                     SLFVPMDRLPLTGNGKLDRRALPTPDYGALSRGRGPRTPGEEIACRIFAEVLGLDRVGV
                     DDSFFDLGGHSLLATRLVSRINEDTGLDLRVRDLFQTPTVAGLLGGGDRAGALDVLLPL
                     QPEGEGRPLFCVHPAAGMSWCFAGLARRIGGPLYGLQSRALREPDALPASVEEIAADYL
                     RRIREVQPEGPYRFLGYSFGGLVAHAMATALQERGEEVELLALMDSYPAHGIEGASAPG
                     HEQMLGMLLGRTPEDPGTAQEREEPFDLDRAVTELRRLDPVLAGFEEPEVAALVTAAVN
                     HVEIAQNFVPGVFEGDVTFFRAELGRMDGTPDTGAWTEHVGGEIDVHRVGATHARMADP
                     GPIEQIGGILAARLDTTDDAAHRGAVKEILT"
     aSDomain        4..885
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B042_RS24005_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.50E-112"
                     /label="B042_RS24005_Condensation_LCL.1"
                     /locus_tag="B042_RS24005"
                     /protein_end="294"
                     /protein_start="0"
                     /score="364.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAGDG"
                     /tool="antismash"
                     /translation="YAQRRLWFLDRVEGPSATYNIPVVLRLRGALDAGALEAALGDVVE
                     RHEALRTVFPSHEGDPHQRVLSCEEARPVLARVGTGAADTADHVARMVRHTFDLERDVP
                     VRAWLLCESEREHVLVLVVHHIAGDGWSMGPLLRDLGRAYRDRSRGAVPDWEPLEIQYA
                     DYALWQRGLLENDADGTPLDVQTEFWKKALEGVPEALDLPADRPRPAVASYRGEVLTFD
                     VPADVHRRLAEVAADHDATLFMAVQAALAVLLDRMGAGSDVPLGTPVAGRADTALEDLV
                     GFFVNTLVLRTDT"
     aSModule        4..3852
                     /complete
                     /domains="nrpspksdomains_B042_RS24005_Condensation_LCL.1"
                     /domains="nrpspksdomains_B042_RS24005_AMP-binding.1"
                     /domains="nrpspksdomains_B042_RS24005_PCP.1"
                     /domains="nrpspksdomains_B042_RS24005_Thioesterase.1"
                     /final_module
                     /locus_tags="B042_RS24005"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       52..168
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0001"
                     /evalue="2.60E-20"
                     /label="C2_LCL_024-062"
                     /locus_tag="B042_RS24005"
                     /protein_end="55"
                     /protein_start="16"
                     /score="64.8"
                     /tool="antismash"
                     /translation="ATYNIPVVLRLRGALDAGALEAALGDVVERHEALRTVFP"
     CDS_motif       370..435
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0002"
                     /evalue="2.00E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="B042_RS24005"
                     /protein_end="144"
                     /protein_start="122"
                     /score="36.2"
                     /tool="antismash"
                     /translation="VHHIAGDGWSMGPLLRDLGRAY"
     CDS_motif       484..519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0003"
                     /evalue="5.30E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="B042_RS24005"
                     /protein_end="172"
                     /protein_start="160"
                     /score="18.9"
                     /tool="antismash"
                     /translation="QYADYALWQRGL"
     CDS_motif       787..876
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0004"
                     /evalue="5.60E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="B042_RS24005"
                     /protein_end="291"
                     /protein_start="261"
                     /score="47.6"
                     /tool="antismash"
                     /translation="DVPLGTPVAGRADTALEDLVGFFVNTLVLR"
     CDS_motif       928..1044
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0005"
                     /evalue="1.40E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="B042_RS24005"
                     /protein_end="347"
                     /protein_start="308"
                     /score="72.1"
                     /tool="antismash"
                     /translation="EADLAAFAHQDLPFERLVEAVNPARSTAHHPLFQVMLTL"
     CDS_motif       1216..1257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0006"
                     /evalue="1.30E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="B042_RS24005"
                     /protein_end="418"
                     /protein_start="404"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="DAESAALLAARLCR"
     aSDomain        1399..2592
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B042_RS24005_AMP-binding.1"
                     /evalue="1.60E-102"
                     /label="B042_RS24005_AMP-binding.1"
                     /locus_tag="B042_RS24005"
                     /protein_end="863"
                     /protein_start="465"
                     /score="335.1"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEDRVNETPDAVALVSGDESLTYAELDTRANRLAHHLIALGVEPE
                     SAVAVLMDRSVHQMVATLAVVKCGAAYVPLAASFPASRVRTIMAETGARALLTDSGARD
                     GVVVAEAGRGTPVAVVDALPADGPGRSPGVRVGDLALLYVMFTSGSTGRPKGVAVDHRN
                     VVGLALDRCWDGDAHRRVMVHSAYGFDASTYEMWVPLLRGSTLVLAPRTDGDARVLADT
                     VRDGGVTAAYFTTGLFNVMADECVEALALLREVWFSGDVASPGALQRVLDHCPDTAVVH
                     GYGPTETTVWSSYQAFGTGERRLDEVHLGTPMDDTTMYVLDDRLRPVPPGATGELYVGG
                     AHVARGYVGRPDLTAERFVADPLGEPGRRMYRTGDLVRWTRQGRIRFIGRIDGQIKIR"
     CDS_motif       1585..1623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0007"
                     /evalue="6.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="B042_RS24005"
                     /protein_end="540"
                     /protein_start="527"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LAVVKCGAAYVPL"
     CDS_motif       1825..1881
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0008"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="B042_RS24005"
                     /protein_end="626"
                     /protein_start="607"
                     /score="29.7"
                     /tool="antismash"
                     /translation="YVMFTSGSTGRPKGVAVDH"
     CDS_motif       2383..2472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0009"
                     /evalue="1.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="B042_RS24005"
                     /protein_end="823"
                     /protein_start="793"
                     /score="52.8"
                     /tool="antismash"
                     /translation="PPGATGELYVGGAHVARGYVGRPDLTAERF"
     CDS_motif       2557..2622
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0010"
                     /evalue="4.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="B042_RS24005"
                     /protein_end="873"
                     /protein_start="851"
                     /score="34.7"
                     /tool="antismash"
                     /translation="FIGRIDGQIKIRGFRIEPAEVE"
     aSDomain        2914..3099
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B042_RS24005_PCP.1"
                     /evalue="1.40E-27"
                     /label="B042_RS24005_PCP.1"
                     /locus_tag="B042_RS24005"
                     /protein_end="1032"
                     /protein_start="970"
                     /score="87.7"
                     /tool="antismash"
                     /translation="EEIACRIFAEVLGLDRVGVDDSFFDLGGHSLLATRLVSRINEDTG
                     LDLRVRDLFQTPTVAGL"
     aSDomain        3166..3852
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B042_RS24005_Thioesterase.1"
                     /evalue="3.70E-39"
                     /label="B042_RS24005_Thioesterase.1"
                     /locus_tag="B042_RS24005"
                     /protein_end="1283"
                     /protein_start="1054"
                     /score="127.4"
                     /tool="antismash"
                     /translation="RPLFCVHPAAGMSWCFAGLARRIGGPLYGLQSRALREPDALPASV
                     EEIAADYLRRIREVQPEGPYRFLGYSFGGLVAHAMATALQERGEEVELLALMDSYPAHG
                     IEGASAPGHEQMLGMLLGRTPEDPGTAQEREEPFDLDRAVTELRRLDPVLAGFEEPEVA
                     ALVTAAVNHVEIAQNFVPGVFEGDVTFFRAELGRMDGTPDTGAWTEHVGGEIDVHRVGA
                     THARMAD"
     CDS_motif       3169..3198
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0011"
                     /evalue="2.40E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="B042_RS24005"
                     /protein_end="1065"
                     /protein_start="1055"
                     /score="10.9"
                     /tool="antismash"
                     /translation="PLFCVHPAAG"
     CDS_motif       3343..3417
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B042_RS24005_0012"
                     /evalue="1.10E-13"
                     /label="NRPS-te1"
                     /locus_tag="B042_RS24005"
                     /protein_end="1138"
                     /protein_start="1113"
                     /score="43.4"
                     /tool="antismash"
                     /translation="QPEGPYRFLGYSFGGLVAHAMATAL"
     gene            3945..4142
                     /locus_tag="B042_RS0120165"
     CDS             3945..4142
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009: mbtH-like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331874.1"
                     /locus_tag="B042_RS0120165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MbtH family protein"
                     /protein_id="WP_028649864.1"
                     /transl_table=11
                     /translation="MTNPFEDTEGRFRVLVNTEGQHSLWPSFADTPAGWSVAKEEDGRQ
                     ACLDYIEENWADIRPASLVG"
     gene            4538..5374
                     /locus_tag="B042_RS0120170"
     CDS             4538..5374
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012509.5"
                     /locus_tag="B042_RS0120170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GHMP kinase"
                     /protein_id="WP_197024372.1"
                     /transl_table=11
                     /translation="MFEHEGRPVRGLVTMPCDLYRSYVVFEPSPAPVLTVSPPDRTKAF
                     RAAAEALAALGRSYTGGHLYLQSDVPLARGFGSSTSDVIASVLAVHDACGRRPDSAVTA
                     RLAVRAELASDSLMFGDRAVLFAQREGVLVEEFAAPLPPLSVLGFGTSRDGAGISTLDM
                     RPAAYGPGEVAEFADLRAGLREAVAAQDPAGVGAVAWASSRINQRHLPVPGFADLEALV
                     RRCGAVGIQVAHSGDIAGLMFDGRDPDIDDARDRAERMLGDLGVEDTWRFSAHARK"
     gene            5384..6418
                     /locus_tag="B042_RS24010"
     CDS             5384..6418
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012512.5"
                     /locus_tag="B042_RS24010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="WP_155989260.1"
                     /sec_met_domain="PALP (E-value: 2.6e-33, bitscore: 109.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPPAVYGSMVEAMVMPRIVRLRPNLHAVVFSLMKLLPAKHIVE
                     QARSSGLLAPGAPVLETSSGTFALGLALVCRHWGHPLTIVGDPAIDPALRTRLEMLGTR
                     VEIVDDFDAPGGIQGARLARLEELRRALPGAFVPGQYDNPGNPGAYLPVAELIATTVGR
                     VDRLVGPVGSGGSSGGISSALRLFGADPRVVGVDTPGSVIFGLDNGPRALRGLGSSIRP
                     GNVVHRSYDEVHWVSAAAAFETTRRLFSERGMFVGPTSGAAHLAADWYARRDGGESTVA
                     VFPDDGYRYQDTVYSEPWLREHGHWAPDLPEEPLLVERPEATDPHWTRIEWGRRPAPEH
                     VSAG"
     gene            6436..6969
                     /gene="rraA"
                     /locus_tag="B042_RS24015"
     CDS             6436..6969
                     /GO_function="GO:0008428 - ribonuclease inhibitor activity
                     [Evidence IEA]"
                     /GO_process="GO:0051252 - regulation of RNA metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="rraA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017596532.1"
                     /locus_tag="B042_RS24015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="WP_051415845.1"
                     /transl_table=11
                     /translation="MTSTTTHPATADLMDAYPALVSCRTQFLRYGGRGSFHGTVATVRC
                     REDNGLVKDAVAEPGRGRVLVVDGGGSLHTALVGDNLAQTAADRGWAGIVVVGAVRDVL
                     GLSRIDIGVLALGTNPRRPSSAGAGTLDGPVSSGGAVFLPGHLLFADGDGVVTGPPDAL
                     PPFSPFRTPSEERS"
     gene            6966..8288
                     /locus_tag="B042_RS24020"
     CDS             6966..8288
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017605343.1"
                     /locus_tag="B042_RS24020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_051415847.1"
                     /transl_table=11
                     /translation="MTTPAHGVSQPTTPSPPGLGPAFHRFWAGSLLSNLADGIMLTALP
                     MVAAMLTNDPILVSGLMVARFLPWLLCGLIAGVVVDRVNRATLMVAANLVRGGAIAVLA
                     VLVATGTASIWVLYAVMFTVMLCEVFYDLSGRAALPDLVPADGLDRANGRLVGGKTVTE
                     DFGGAPLAGFLFVVATALPLAVNAGAYVLGALVLLGLPLAVRRPESGEPAPRTSGGAAS
                     GAVRAVLTEIRAGLGFVFGDRALRSPVLFGVVVNMAFMAQAGVLVLLVQEHFGVPEALY
                     GVFLASSAVGALLGSALVGKVAAKLGRFRTELVSFGAMGLCCLAFGLAPSAYLAALAWM
                     LLGTAMTVSNVVMIGSAQMIVPGDRLGRVMSVIQVLGFGLAPVGALLGGLLGRVELHYV
                     PVAAGTVLLVSLVLAVPGLRALTARADEAEAAVVAAAREGA"
     gene            8389..8814
                     /locus_tag="B042_RS0120195"
     CDS             8389..8814
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017609185.1"
                     /locus_tag="B042_RS0120195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_028649866.1"
                     /transl_table=11
                     /translation="MRYLMSIMSTPESEATDHDNPPEVYEMMAAYNEEMIKAGVLLTGE
                     GLAPTSEGAEIVFRGGEVTVTDGPFTEAKEFIAGYWVLQVSSHEEALEWARRCPHPPAD
                     SDVVLKLQLRRIAELEDLDKMPEELKERERELRSQGY"
     gene            complement(8900..10756)
                     /locus_tag="B042_RS24025"
     CDS             complement(8900..10756)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012708.5"
                     /locus_tag="B042_RS24025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FHA domain-containing protein"
                     /protein_id="WP_081748907.1"
                     /transl_table=11
                     /translation="MSFEIVGREGPFAQQRFPVGDVPITFGRHASNSVVVVSKLASRFH
                     AEILPEGGVYVLYDRESSNGTTVNGEPTASHVLRPGDLITIGDEVFCWEPSETQEASPP
                     VTQLFVRPDAASGPVMNVTVSGGGPVGLAFALLTDHLLGGRASVTVYDARWTRDNGRVV
                     WKNEKQGNVRRQQVVTIQSRQYLNLSEEMQERLFAPGTYTEMWPSGADSIRGLGPRNIR
                     ISRIEDVLLEMASERPGRIRLVPEKFNVTEDPNALDDTHVLAVCEGSRSRSREHFTKKF
                     GQADTSIYSLDGQHLEDVVLGLRVKSKLSDPATVLLTVAQNRYLLNSLEGQGFLNMRLT
                     DAEAREVVGIDPVRQVFEQCIGSRPCVMARDGEDDDFSCSTHNSLFLPSLIKGSPLWKR
                     VRQGLELFGVPESDLKAVTAFRLSMVQRPRFTAELRSPGSRNPGTYGFLLGDAANAIHF
                     WPGRGLNSGLASAISLARSLSSAWNGRPFRDSDFIRHEAAMSMLQYRHKSRAWKAMVTA
                     ADDGSEIAIKDKIAQSIEAPGSDREADLETLLERLGSIRERLSARIPGMPDDASLRDHL
                     GGLSDETLRSLVAGGPWDTLTVGGEEVDIDIFYREEAEAAKG"
     misc_feature    10811..10825
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.68"
                     /tool="antismash"
     gene            11197..12453
                     /locus_tag="B042_RS0120205"
     CDS             11197..12453
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017533075.1"
                     /locus_tag="B042_RS0120205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_028649867.1"
                     /transl_table=11
                     /translation="MSHGDTTRAVEAVWRIESARLIGALTRMVGDVGLAEEFAQDALVS
                     ALEKWPEEGVPSTPGAWLTTVAKRRVLDRWRRDERFKDRMADLGRGAAENDGQAEFDAA
                     LEEDYGDDVLRLMFVCCHPVLSGKARVALTLRMLGGLSTDEIARAFLVPEPTVAQRIVR
                     AKRTLAKRRVPFEVPAGADRDARLSSVLDVLYLVFNEGYTATSGADWTRADLCEEAMRL
                     GRVLAALLPEEREVHGLLALMELQASRLRARSGTDGRPVPLADQDRSRWDRLLITRGLR
                     SLARSVPRDPAEPRGAYSLQAGIAAEHARALGADDTDWVAIALLYERLVRLTRSPVAEL
                     NRAVAVSMALGPAPALEIVDALRGIPELAGYHPLPAVRGDLLVRLGRSGEARSEFERAA
                     ELTRNERERELLLERARSG"
     misc_feature    12588..12605
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.02"
                     /tool="antismash"
     gene            12709..13422
                     /locus_tag="B042_RS0120210"
     CDS             12709..13422
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569530.1"
                     /locus_tag="B042_RS0120210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_036555802.1"
                     /transl_table=11
                     /translation="MSKAFRGHRAVDGVSFTVEPGTVTGFLGPNGAGKTTTLRCLLGLV
                     RPDRGEGLFGGRPYASLPAPASEVGAVLEANNLHPGRSGRNHLRTLCDAEGLPLSRADE
                     VLDEVGIAEAGGKRVAGYSMGMRQRLSLAGALLGDPRVLILDEPANGLDPRGIDWLRRF
                     LDYQAHERGVAVLVSSHVLAEVEQTVDNVVIIARGRLVHQGTLSELTGGGESLHEAFLR
                     LTDQENSEQPVGGSR"
     gene            13419..14186
                     /locus_tag="B042_RS0120215"
     CDS             13419..14186
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017563352.1"
                     /locus_tag="B042_RS0120215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_028649869.1"
                     /transl_table=11
                     /translation="MTALVRSELRKVFTTRLWWIMLLAALAWVGLSLGLIIVSAGMEGG
                     FAADSAEYAGAVWPMGASGTLFALVVGIVVVTSEYQHRTVNTTFLVSPRRLPVVLAKAV
                     AAALVGLLFGAVVVGLSAVVAGASILAGGGELNLVDNQVPRVLLGSVAAHVAYTVIGVG
                     VGALIRHQVAALVVGILWVFMLEPILVVVPQLQDVGRWLPGGAVSALYDTGVDYGMGAM
                     ELLPVWGASMVLAGYAAVAIALAAATTLRRDVA"
     gene            complement(14207..14365)
                     /locus_tag="B042_RS25960"
     CDS             complement(14207..14365)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS25960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_197024373.1"
                     /transl_table=11
                     /translation="MGCGSAANHNPAFYADDSVLLTGARLHANMAVDHVTGRVDPHLSG
                     QPGPPAF"
     gene            complement(14497..14673)
                     /locus_tag="B042_RS25415"
     CDS             complement(14497..14673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019609900.1"
                     /locus_tag="B042_RS25415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_081748908.1"
                     /transl_table=11
                     /translation="MTAEWHKSSYSSGNNECVEVREHASGADVRDTAHRDAGHVTVPLS
                     QWVALIAEVRKTQ"
     gene            complement(14670..15653)
                     /locus_tag="B042_RS0120230"
     CDS             complement(14670..15653)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="B042_RS0120230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_081748909.1"
                     /transl_table=11
                     /translation="MFGSTQQLSAAKRKHELGAGKKPEMPHNQGRCESDASFCVIVAEL
                     TRQSLWHSARMATESPHYAWREFGAKLSYLRNMSGLSQEDLAKRCGMARSTLGGHETGH
                     RKPRRRDVESLDRELGAHGGVLRAWETARRLDDNPEWYREITEAEKYAISIEIFHSALI
                     PGRFQTPDYARAVLTDCRPGDDPANVERLMKIRTSMLPRLLSQNRPRMLVVLAEYVIRH
                     TIGSPEIQAKQLDHLLKLQTDGTLRLLIVPSGTENRAGVATGPFRLISFEERLPLAYAE
                     HASGGVVIDQRDEVRRLGAIFGEQMSWALTPAASLDLVKQVRGDLA"
     misc_feature    complement(14910..14912)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15910..15925)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            16025..16210
                     /locus_tag="B042_RS24560"
     CDS             16025..16210
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS24560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="ATP-binding protein"
                     /protein_id="WP_028649872.1"
                     /transl_table=11
                     /translation="MVDQGPGHGTVPCIRPLGTEEDGRFGGFGLRLVNAFASRWGYESG
                     QRRTTVWFEVDRLPGR"
     misc_feature    complement(16216..16226)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            16216..16476
                     /locus_tag="B042_RS24035"
     CDS             16216..16476
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155989262.1"
                     /transl_table=11
                     /translation="MAWHVEDDRPFYATARRLQHAVGSRWVVLWGPASRRYWALPCGTA
                     TAPVLSDPDPDRLYAMAQRQAAGRPATGTAAPAPSEHRQPR"
     misc_feature    16232..16246
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.5"
                     /tool="antismash"
     gene            16911..17165
                     /locus_tag="B042_RS0120255"
     CDS             16911..17165
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS0120255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155989264.1"
                     /transl_table=11
                     /translation="MVITCPAPIYVQVVDPSSGPETEPHRNRAEIAFVADESGPRLVLT
                     RDTTWGVDSNANGATAWFALHPSDSPALEPAPSGPEPQS"
     gene            17373..17510
                     /locus_tag="B042_RS26280"
     CDS             17373..17510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017613967.1"
                     /locus_tag="B042_RS26280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_197024375.1"
                     /transl_table=11
                     /translation="MDASTQIADEELNVAVEEIAAVRSRAEQPSDGGSTGRGDTNDGIR
                     "
     gene            17520..19589
                     /locus_tag="B042_RS26775"
     CDS             17520..19589
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012472.5"
                     /locus_tag="B042_RS26775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_231494158.1"
                     /transl_table=11
                     /translation="MTADLISGRLGGDTFPAQVLGRTHRHYPAPEDERDAFRHLLTWSD
                     LNTLLSSQRLDSPRMRLSAGEVIDAGEYTRLRQYRRMPDWNAPVPHLFHQRLREGATLV
                     LDAIDEMHPPIGRLISELEAWLRTGIQVNAYASWTSKEGFGVHWDDHDVIVLQVSGRKR
                     WRIYGTTRIAPLHDDVEFAEEEPTEIIDEFVMEPGDVLHVPRGCWHAVAASEGEPSLHL
                     TCGLVTTTGVNFLRWLVNKLIEHDEVRAHIPRAPDEYAAWTRRISELVTDRLRAPEVVE
                     EYWRHQDETSPARGRRHRRAGSYRRRPVRLPARYRHRDRWRGGLLRPGAALAAPGQGRP
                     RDHSPAPRWSRLDQGAERAGPQRVREGAARPVPQADGRRGSGPGGRGMTVIGMGTYRSR
                     DAVTSASIAASDGCPLIDTAPVYGGGTHQVAIAPVLRDHPEVRVSTKVGYMTEGQARVA
                     FTSTALSEEEAAFRHSIAPDYVRHQVAMSRTELKRTSPDLVYLHNPEHHHEERGDLHQR
                     LRSAFAVLEDLYASGGIGGYGVSTWNGFESGTFTLADLLRLAEEAAGGPETGLSAIQLP
                     VSMVKIAPVHQALAGSGPIAQADEAGLEVWASAPLHGGELLRLINPSLAEAVHPGASPV
                     EAALKFASSVPGLTGVLISTTDSAHYKQAVEAIREPLPDHRLKELCDVLAPPSR"
     gene            19561..20403
                     /locus_tag="B042_RS0120280"
     CDS             19561..20403
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017587660.1"
                     /locus_tag="B042_RS0120280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase"
                     /protein_id="WP_028649877.1"
                     /sec_met_domain="APH (E-value: 3.1e-07, bitscore: 24.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSPRLPDDLTDRWHHAAESLKSSAAADVPLCSGLGGRTLSGPV
                     TAADGHPAWLRLIAASRPGGKIWEGAALADTLLDEAIPRPVMLGEHTWQEEGAAFQATL
                     WTRLRGEVLSPTPDLSTPVDVDDRWWKSLRTWVEKVRSTAVPPGREVMTQAYIDRIPRF
                     IPVLEGADLTVPRWESAHGDLHWGNITGDPLEIIDWEGWGAAPAGYDAAVLLAYALPAP
                     ATAAKVREVFGDMLNTGPGRLAQLVICAEIIQASERDDLHARLRPYAERLAADVLAPQ"
     gene            complement(20558..21889)
                     /locus_tag="B042_RS0120285"
     CDS             complement(20558..21889)
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017601304.1"
                     /locus_tag="B042_RS0120285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase"
                     /protein_id="WP_028649878.1"
                     /transl_table=11
                     /translation="MTGTTIADVAPLHEAVDRRAAAIESKIVAWRHHLHAHPELPNREA
                     ETAAFAAEHLRSLGLDEVRTGVAGHGVVGVLRGGLGGDRVAALRADIDALPVKEESGVG
                     FASTAVDADYPGGPFPVAHACGHDCHTAMVMGAAEVLAGMRSDLPGTVLFVFQPAEEGP
                     PVAEEGGARSMVGSPALRDPAPTMVFGLHVVPLPKGVVGYRAGHQYAASCMVRITVHGK
                     QVHASMPWMGLDPMPPAADIVSACGQIYRRIPATSPVTVSIGHVEDQGRFNIIGETVTL
                     WGTIRCLHDGDMDTVRDHLRRTAEHTAQAHGCTAEAEFLQDVPAVDNTPEWTSAALPTL
                     RRVVGEDRVKQTEPSLGYDDVSEFVRAFGGVYVMLGCQDTEYAHGALRSIPGQRGSAAN
                     HNPAFYADDSVLLTGARLHATMAVDHVTGRVDPALTGQPGPPAF"
     gene            complement(22005..22601)
                     /locus_tag="B042_RS0120290"
     CDS             complement(22005..22601)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911122.1"
                     /locus_tag="B042_RS0120290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_028649879.1"
                     /transl_table=11
                     /translation="MTVMEHSSPRSPVEKLSVAQFEVIAQAAAREDVTLEYLNGEMEIR
                     TVPDSDHNAILMWLTRQCMAQRADLDLNVTGQGLKVDAYRKGRVRPDGLLAPVDHFIGQ
                     GEWADPRGVLAVVEATSWDVDTNARDRVEKAQAYAACGIGVYLLIDRDDDSVTVHGEPV
                     DGRYRSITTLGYGHTVEIPGTGIVLSTGELKRYAR"
     gene            22728..22988
                     /locus_tag="B042_RS24045"
     CDS             22728..22988
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS24045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_036555754.1"
                     /transl_table=11
                     /translation="MRTTIEIPDDLYRQALSIAEDTSRSLGETVTELMCRGLGQNGGAG
                     GISRSARTGLPVVHLGTVITTGEVRALADDDLGRMSTGHTV"
     gene            complement(22998..23258)
                     /locus_tag="B042_RS0120300"
     CDS             complement(22998..23258)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS0120300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028649880.1"
                     /transl_table=11
                     /translation="MTERCGARPGAGPTCVPGVGRIHRLRPRPGPALPGKGQHRRALPD
                     LIIAVTAEAHGATVVHYGKDYDLISAVTGQPTLWIVPAGTV"
ORIGIN
        1 tacgctcaac gcagactctg gttcctggac cgtgtggagg ggccgagcgc cacctacaac
       61 atcccggtgg tgctgcgcct gcgcggtgcc ctggacgccg gtgccctgga ggcggcgctg
      121 ggggacgtgg tggagcggca cgaggcgttg cggacggtgt ttccctccca tgagggcgac
      181 ccccaccagc gggtgctctc ctgcgaggag gcgcgccctg tcctcgcccg ggtggggaca
      241 ggggcggccg acaccgccga ccacgtcgcg cggatggtgc ggcacacgtt cgatctggag
      301 cgggacgttc cggtgcgggc gtggctgctg tgcgagtcgg agcgtgagca cgtgctggtg
      361 ctggtggtgc accacatcgc cggtgacggg tggtcgatgg gtccgctgct gcgggatctg
      421 gggcgggcct accgggaccg gtcccggggc gcggttccgg actgggagcc gctggagatc
      481 cagtacgccg actacgcgct ctggcagcgc ggcctcctgg agaacgacgc cgacggcacc
      541 cccctcgacg tccagaccga gttctggaag aaggccctgg agggcgtccc cgaggcgctg
      601 gacctgcccg ccgaccggcc ccggcccgcc gtcgcctcct accgcggaga ggtcctcacc
      661 ttcgacgtcc ccgcggacgt ccaccgcagg ctcgccgagg tcgccgccga ccacgacgcc
      721 accctgttca tggcggtcca ggccgccctg gcggtcctgc tggaccggat gggcgccggc
      781 tccgacgtcc cgctcggcac acccgtcgcc ggacgcgcgg acacggcact ggaggacctg
      841 gtggggttct tcgtcaacac cctggtcctg cgcaccgaca cctccggcaa ccccgggttc
      901 ggcgcgctcc tggaacgggt gaaggaggcc gacctggccg ccttcgccca ccaggacctg
      961 cccttcgagc ggctcgtgga ggcggtcaac cccgcccgct ccaccgcgca ccacccgctc
     1021 ttccaggtca tgctcaccct ccagaacgac gccggggcct ccctggggct gcccggactc
     1081 gacgtggccg aggagccctg cgccacgggc atggccaagt tcgacctcac cttcgtcctc
     1141 agggagcgcc gcggacccga cggtgccccc gccgggctcg acggtggcct ggagtacgcc
     1201 accgacctgt tcgacgccga gagcgccgca ctgctagcgg cccggctgtg ccgcctgctc
     1261 gacgccgcct cggcagcccc cgccaccggg gtgcgcgacc tgccggtcct gacggaggag
     1321 gagtacacgc atgctgtgga ggagtacaac ggcaccgccg tcaccgcgcc tccccgcgcc
     1381 ctggtccacg aactcttcga ggaccgcgtg aacgagaccc ccgacgcggt ggccctggtc
     1441 agcggggatg agagcctcac ctacgccgaa ctggacacgc gcgccaaccg gctcgcccac
     1501 cacctgatcg ccctcggcgt ggagcccgag tccgcggtgg ccgtgctcat ggaccgctcc
     1561 gtccaccaga tggtggccac cctcgcggtc gtcaagtgcg gggccgccta cgtcccgctg
     1621 gccgcctcct tccccgcctc ccgggtgcgg accatcatgg ccgagacggg ggcccgggcc
     1681 ctgctcaccg acagcggcgc gcgcgacggc gtcgtcgtcg ccgaggccgg gcgggggacg
     1741 ccggtcgccg tggtcgacgc cctgcccgcc gacggccccg ggcgcagccc cggggtacgg
     1801 gtcggggacc tggccctgct gtacgtgatg ttcacgtccg ggtccaccgg caggcccaag
     1861 ggcgtggcgg tcgaccaccg caacgtcgtc ggcctggccc tggaccgctg ctgggacggg
     1921 gacgcccacc gccgggtcat ggtgcactcc gcctacgggt tcgacgcgtc cacctacgag
     1981 atgtgggtac cgctcctgcg cgggtcgacc ctggtcctgg caccgcgcac cgacggcgac
     2041 gcccgggtcc tggccgacac cgtccgggac gggggcgtga ccgccgccta cttcacgacc
     2101 gggctgttca acgtcatggc cgacgagtgc gtggaggccc tcgccctgtt gcgcgaagtg
     2161 tggttcagcg gggacgtcgc ctcacccggc gccctccaga gggtcctgga ccactgcccc
     2221 gacacagcgg tggtccacgg gtacgggccc acggagacga ccgtgtggtc gagctaccag
     2281 gccttcggca ccggggagcg ccggctcgac gaggtccacc tgggcacccc catggacgac
     2341 accaccatgt acgtcctcga cgaccggctc cggccggtcc cgcccggggc caccggtgaa
     2401 ctgtacgtgg gcggcgcgca cgtggcccgc ggatacgtcg ggcgcccgga cctgaccgcg
     2461 gaacggttcg tcgccgatcc gctcggagag cccggtcgcc gcatgtaccg gaccggggac
     2521 ctggtgcgct ggacccggca gggccggatc cgcttcatcg gccggatcga cggacagatc
     2581 aagatccggg ggttccggat cgagccggcc gaggtcgagg cggtactcgg ctccagaccc
     2641 ggggtgtccc agtgcgcggt ggtggtccgc gaggaccgcc ccggagacaa gcggctcgtc
     2701 gcctacgtgg tgctcgaccc cggtcacggc ctggaccggg cggaactgcg ccggagcatg
     2761 ggcgagaccc tgcccgacta catggtcccc tcactgttcg tgcccatgga ccggcttccg
     2821 ctgacgggca acggcaagct ggaccgccgt gccctgccca cccccgacta cggggcgctc
     2881 tcccgggggc gcggcccccg cacgcccggg gaggagatcg cgtgccggat ctttgccgag
     2941 gtcctgggcc tggaccgtgt cggggtcgac gactccttct tcgacctggg cggccactcc
     3001 ctgctcgcca cccgcctggt gagccgcatc aacgaggaca ccggactcga cctgcgggtg
     3061 cgggacctct tccagacccc cacggtcgcc gggctcctcg gcggcgggga ccgcgccggc
     3121 gccctcgacg tcctgctgcc cctccaaccg gagggcgagg ggcgtccgct cttctgcgtc
     3181 caccccgccg cggggatgag ctggtgcttc gcgggtctgg cccgccggat cggcgggccc
     3241 ctctacgggt tgcagagccg ggcgctgagg gaacctgacg cgcttcccgc gagcgtggag
     3301 gagatcgcgg cggactacct ccgccggatc agggaggtgc agcccgaggg gccctaccgg
     3361 ttcctgggct actccttcgg ggggctggtc gcccacgcca tggcgaccgc cctccaggaa
     3421 cggggcgagg aggtcgaact gctcgccctg atggactcct accccgccca cggcatcgag
     3481 ggtgcgtccg cgcccggcca cgagcagatg ctgggcatgc tcctgggccg gactccggag
     3541 gatcccggaa ccgcacagga gcgggaggag cccttcgacc tcgaccgggc ggtgaccgaa
     3601 ctgcgccgcc tggacccggt cctggccggt ttcgaggagc ccgaggtggc cgcgctggtc
     3661 accgccgcgg tcaaccacgt ggagatcgca cagaacttcg tcccgggtgt cttcgagggt
     3721 gatgtcacct tcttccgggc ggaactggga cggatggacg gaacacccga caccggtgcc
     3781 tggaccgagc atgtgggagg tgagatcgac gtacaccggg tcggggcgac acacgcgcgc
     3841 atggcggacc caggaccgat cgaacagatc ggcgggatcc tggccgcgcg gttggacacc
     3901 accgacgacg ccgcacaccg cggcgcagtg aaggagatcc tgacatgacc aaccccttcg
     3961 aggacaccga gggccgcttc cgcgttctgg tcaacacgga gggccagcac tcgctgtggc
     4021 cgtccttcgc ggacaccccg gccggctggt ccgtggccaa ggaggaggac ggccgccagg
     4081 catgcctgga ctacatcgag gagaactggg ccgacatccg gcccgcgagc ctggtcggct
     4141 gaccccgccc gcccggtgac gtccccggtg cccgccacga gcgggaccgg ttcgggccga
     4201 cggctacggg ccgtcggccg gcgaagagcc ccggactcgg agcgaacctc cgagtccggg
     4261 gctctcgcgt attcgggaaa gccctggtgg gactgccggt cggctgccgc cccgcactgc
     4321 ctggcgggcg ggcccggact ccgtagtgtc tttcctgacc ggagccgggt gtgcggcgat
     4381 gtgccacgga atgggtaacg gaatgcggac atcggaagac gagacgacca gtgacacaag
     4441 ctccccgagg acgtcccgag ccccccgagc cgcgtcccgc gcggtcggta tgggcttcgg
     4501 ctcctctctg gcgcaccacg gggagatcct tcaggggatg ttcgagcacg aggggcggcc
     4561 cgtccgcggg ctggtgacga tgccctgcga cctctaccgc tcctacgtgg tcttcgagcc
     4621 ctcccccgcc cccgtgctca cggtgagtcc gcccgacagg accaaggcgt tccgggccgc
     4681 ggccgaggcc ctcgcggccc tgggccgctc ctacaccggg gggcacctct acctccagtc
     4741 cgacgtcccg ttggcccgcg ggttcggatc ctccaccagc gacgtgatcg cctcggtcct
     4801 ggcggtccac gacgcctgcg gacgcagacc cgacagcgcc gtgacggccc ggctcgcggt
     4861 ccgcgccgag ctggcctcgg actcgctgat gttcggcgac cgggcggtgc tgttcgccca
     4921 gcgagaaggg gtcctggtcg aggagttcgc cgctcccctg ccgcccctgt ccgtgctcgg
     4981 gttcgggacc agccgggacg gcgcggggat ctcgaccctg gacatgcggc ccgccgccta
     5041 cggccccggc gaggtcgccg agttcgccga cctgcgcgcc ggactgcgcg aggccgtggc
     5101 cgcacaggac ccggcggggg tcggagcggt cgcctgggcc agcagcagga tcaaccagcg
     5161 ccacctcccg gtccccggat tcgcggacct ggaggccctc gtccgccggt gcggggccgt
     5221 ggggatccag gtggcgcaca gcggggacat cgcgggcctg atgttcgacg gccgcgatcc
     5281 cgacatcgac gacgcccggg accgcgccga acggatgctc ggcgacctcg gcgtcgagga
     5341 cacctggcgc ttctccgccc acgcacgaaa gtagggaccc ccgatgaacc agccacccgc
     5401 ggtctacggc tcgatggtcg aggcgatggt catgcctcgt atcgtgcgcc tgcgccccaa
     5461 cctccacgcg gtcgtcttca gcctcatgaa gctcctgccg gccaagcaca tcgtcgaaca
     5521 ggcccggtcc agcgggctcc tggcaccggg cgcacccgtg ctggagacct cctcggggac
     5581 cttcgccctc ggcctggccc tggtctgtag gcactggggg cacccgctca cgatcgtcgg
     5641 cgaccccgcc atcgaccccg cactgcggac ccggctggag atgctgggga cccgggtcga
     5701 gatcgtcgac gacttcgatg ccccgggcgg tatccagggc gcgcgcctgg cccgcctgga
     5761 ggagttgcgc cgcgcactgc ccggtgcgtt cgtacccggc cagtacgaca accccggaaa
     5821 ccccggtgcg taccttccgg tggccgagct gatcgccacg acggtcggcc gggtggaccg
     5881 cctggtcggc ccggtgggct cgggcggttc cagcggtggc atctccagcg cgctccgcct
     5941 gttcggagcg gatccgcggg tggtcggcgt ggacaccccg ggcagcgtca tcttcggcct
     6001 ggacaacggc cctcgggcgc tgcgcggcct cggcagcagc atccggccgg ggaacgtcgt
     6061 ccaccgctcc tacgacgagg tgcactgggt gagcgccgcg gccgcgttcg agaccacacg
     6121 ccgcctgttc tccgagcgcg gcatgttcgt gggccccacc agcggcgccg cccacctggc
     6181 cgctgactgg tacgcccggc gcgacggcgg ggagagcacc gtcgccgtct tccccgacga
     6241 cggctaccgg taccaggaca ccgtctacag cgagccgtgg ctgcgcgagc acgggcactg
     6301 ggcccccgac ctgccggagg agccgctcct ggtggagcgc cccgaggcca ccgacccgca
     6361 ctggacgcgg atcgagtggg gccgccgccc cgcacccgaa cacgtttccg caggctgacc
     6421 gaggagtcca cgaccatgac gagcaccacc acacacccgg ccaccgcgga cctcatggac
     6481 gcctaccccg ccctggtgag ctgccggacc cagttcctgc gctacggggg ccgcggatcc
     6541 ttccacggga ccgtcgccac cgtgcgctgc cgcgaggaca acggcctggt gaaggacgcg
     6601 gtcgctgaac ccggtcgggg ccgtgtcctc gtcgtggacg gcggcggatc gctgcacacc
     6661 gccctggtcg gggacaacct cgcccagacc gccgccgacc gcggatgggc cgggatcgtc
     6721 gtcgtcggcg cggtgcgcga cgtcctcgga ctctcccgta tcgacatcgg cgtgctcgcg
     6781 ctgggcacca acccgcgcag gccgtccagt gcgggagccg gaaccctcga cggaccggtc
     6841 tcctccgggg gcgcggtgtt cctgccggga cacctgctct tcgccgacgg ggacggtgtc
     6901 gtgaccggcc caccggacgc actcccgcct ttctccccct tccgcacccc ttccgaggag
     6961 aggtcatgac cacccctgcc cacggcgttt cgcagccgac gacaccgagt ccgcccgggc
     7021 tcggcccggc cttccacagg ttctgggccg gaagcctgct cagtaacctc gccgacggga
     7081 tcatgctcac cgccctgccc atggtggcgg cgatgctgac caacgacccg atcctggtgt
     7141 cgggtctgat ggtggcccgc ttcctgccgt ggctcctgtg cggcctcatc gccggggtgg
     7201 tcgtggaccg cgtgaaccgc gccacgctca tggtcgcggc caacctcgtg cgcggcggtg
     7261 ccatcgcggt cctggccgtg ctggtggcca ccggaaccgc gtccatctgg gtgctgtacg
     7321 ccgtgatgtt cacggtgatg ctctgcgagg tcttctacga cctctcgggg cgcgcggccc
     7381 tgcccgacct ggtcccggct gacgggctgg accgggccaa cggtcgcctg gtcggcggaa
     7441 agaccgtcac ggaggacttc ggcggcgccc cgctggccgg cttcctcttc gtcgtcgcga
     7501 ccgcgctccc gctggcggtg aacgccggtg cctacgtcct cggggccctg gtgctgctcg
     7561 gcctcccgct ggcggtacgc cgccctgaga gcggcgaacc ggccccgcgg acgtccgggg
     7621 gcgcggcctc cggcgccgtc cgcgccgtcc tcacggagat ccgtgccggt ctgggattcg
     7681 tgttcggcga ccgggcgctg cgctcccccg tcctgttcgg ggtggtcgtg aacatggcgt
     7741 tcatggccca ggccggtgtc ctggtcctcc tcgtgcagga gcacttcggt gtcccggagg
     7801 ccctctacgg cgtgttcctg gcctcctcag cggtcggggc gctgctcggt tcggcgctgg
     7861 tcggcaaggt cgccgcgaaa ctgggccggt tccgcaccga actcgtgtcc ttcggagcca
     7921 tggggctgtg ctgcctggcg ttcggcctgg cccccagcgc ctacctcgcg gctctggcct
     7981 ggatgctgct cggaaccgcc atgacggtct ccaacgtcgt catgatcggt tcggcgcaga
     8041 tgatcgtgcc cggtgaccgc ctcgggaggg tgatgtcggt gatccaggtc ctcgggttcg
     8101 gcctcgcccc ggtgggcgcg ctcctgggcg gcctgctggg ccgggtggaa ctccactacg
     8161 tccccgtggc cgccggtacg gtcctgctcg tctccctggt tctggccgtc cccggcctgc
     8221 gcgcgctgac cgcccgcgcc gacgaggcgg aggcggccgt cgtggcggcg gcccgggagg
     8281 gggcctgaga aaaattgtcc ggggcgtgtc gatccggcgc ggggccgttc gacgggtagg
     8341 tgagagcggg ggagaagagc cctcaccagg aacggaaagg cgaaggccgt gcgctacctg
     8401 atgtcgatca tgtccacccc ggagtccgag gccaccgacc acgacaaccc gccggaggtc
     8461 tacgagatga tggcggccta caacgaggag atgatcaagg ccggtgtcct gctgaccggt
     8521 gaggggctcg cccccacgtc ggagggggcc gagatcgtct tccggggcgg tgaggtgacc
     8581 gtcaccgacg gccccttcac cgaggccaag gagttcatcg ccgggtactg ggtcctccag
     8641 gtctcctccc acgaggaggc gctggagtgg gcgcggcgct gcccgcaccc gccggccgac
     8701 agcgacgtgg tgctcaagct ccagttgcgc cggatcgccg aactggagga tctggacaag
     8761 atgcccgagg aactgaagga gcgcgagcgc gagctgcgct cccaggggta ctgaccaggg
     8821 gcactgggac cggaccgggg cccgcggtgc cggtggcacc gcgggccgcc gctgccggtg
     8881 gcccgccccc gggcgaacgt cagcccttcg ccgcctcggc ctcctcccgg tagaagatgt
     8941 cgatgtcgac ctcctcgccg ccgaccgtca gcgtgtccca cgggccgccg gccaccaggg
     9001 agcgcagggt ctcgtcgctc aggccgccca ggtggtcgcg cagcgacgcg tcgtcgggca
     9061 tgcccgggat gcgcgcggac agccgttcgc ggatcgaacc cagccgctcc agcagggtct
     9121 ccaggtccgc ttcccggtcg gagcccggtg cctcgatgct ctgggcgatc ttgtccttga
     9181 tcgcgatctc cgagccgtcg tcggcggcgg tcaccatcgc cttccaggcc cggctcttgt
     9241 gccggtactg gagcatcgac atcgccgcct cgtggcggat gaagtccgag tcgcggaagg
     9301 ggcggccgtt ccacgcgctg ctgagcgagc gcgccaggga gatggccgag gccaggccgc
     9361 tgttgagccc ccgcccgggc cagaagtgga tcgcgttggc ggcgtcaccg agcaggaagc
     9421 cgtaggtgcc cgggttcctc gaccccggtg agcgcagctc cgcggtgaac cggggccgct
     9481 gcaccatgct cagccggaag gcggtgacgg ccttgaggtc ggactcgggc acaccgaaca
     9541 gctccagccc ctggcgcacc cgcttccaga ggggcgaccc cttgatcagg gagggcagga
     9601 acagcgagtt gtgggtggag caactgaagt cgtcgtcctc gccgtcgcgc gccatcacgc
     9661 acgggcgcga gccgatgcac tgctcgaaca cctgtcggac cgggtcgatc ccgacgacct
     9721 cccgggcctc ggcgtcggtg aggcgcatgt tgaggaagcc ctggccctcc agcgagttca
     9781 gcaggtagcg gttctgcgcc acggtcagca ggacggtcgc ggggtccgac agcttggact
     9841 tgacgcgcag gcccagcacc acgtcctcca ggtgctgccc gtccagtgag tagatcgacg
     9901 tgtccgcctg cccgaacttc ttggtgaagt gctcccggct gcgggagcgc gacccctcgc
     9961 acaccgcgag cacgtgggtg tcgtccaagg cgttcgggtc ctcggtgacg ttgaacttct
    10021 cggggacgag cctgatgcgc ccgggccgct cggaggccat ctccaggagg acgtcctcga
    10081 tccgggagat gcggatgttg cgcgggccca gcccgcggat cgagtcggcg cccgagggcc
    10141 acatctcggt gtaggtgccg ggtgcgaaca gccgctcctg catctcctcg gagaggttga
    10201 ggtactggcg gctctggatc gtcacgacct gctggcgccg gacgttgccc tgcttctcgt
    10261 tcttccacac gacacggccg ttgtcgcggg tccagcgcgc gtcgtagacg gtgacggacg
    10321 cccggccgcc gaggaggtgg tcggtcagca gggcgaaggc caggccgacg ggaccgccgc
    10381 ccgagaccgt gacgttcatg accggtccgg acgcggcgtc ggggcggacg aacaactggg
    10441 tcaccggagg gctggcctcc tgcgtctcgg agggctccca gcagaacacc tcgtcgccga
    10501 tggtgatcag gtcgccgggg cgcaggacgt gggacgccgt cggctcgccg ttgaccgtgg
    10561 tcccgttgct gctctcacgg tcgtagagga cgtaaacgcc cccctcgggg aggatctccg
    10621 cgtggaagcg ggaggccagc ttgctcacga ccaccacgct gttgctggcg tggcggccga
    10681 aggtgatcgg cacatcgccc accgggaacc gctgctgggc gaaggggcct tcacggccga
    10741 cgatctcgaa tgacacagcc tgcttctttc tgtcaggggg acgggctctg ctcgggggcc
    10801 tggggcggcc ttctcgttct gggacgcggg agggcggcct gcggatctga ttttcccgga
    10861 atccctcaca cagcaggtat tccggacgga tgcctgccta ccccgtgggg gagcgggaac
    10921 gcggccacga ccccgcccgc acgggtgccg gccggcccgg tcgcctcggt ccgtgcaccg
    10981 gggatgagca gcgggtgacg cttctccccc ggtcggggtg ttctcccgcc cgtgccacgg
    11041 tgtgcgcacg cacggccccg ccgggcggtg gagagggagg tcacccgcga cgatggcgtg
    11101 ggcggttttc ggtcgcgggt cgaatctgtt tctgtggcct ttcgcaaagc ggggagcgtg
    11161 cttgcggtgt gtgacctgcg gtgctttcat tgcaccgtga gccacgggga taccacgcgc
    11221 gcggtggagg cggtctggcg catcgagtcg gcgcgcctca tcggagcgct cacccggatg
    11281 gtgggcgatg tcggcctggc cgaggagttc gcccaggacg ctctggtcag tgccttggag
    11341 aagtggcccg aggagggtgt gccgagcaca ccgggcgcct ggctgaccac cgtggccaaa
    11401 cgccgcgtcc tcgaccgctg gcgccgcgac gagcggttca aggaccgcat ggccgacctc
    11461 gggcgcgggg ccgccgagaa cgacgggcag gccgagttcg acgccgcgct ggaggaggac
    11521 tacggcgacg acgtcctccg gctcatgttc gtgtgctgcc acccggtcct gtccggcaag
    11581 gcgagggtgg ccctgaccct gcgcatgctc ggcggcctgt ccacggacga gatcgcccgc
    11641 gccttcctgg tgcccgaacc gaccgtggcg cagcggatcg tgcgggccaa acgcaccctc
    11701 gccaagagga gggtgccctt cgaggtgccc gccggagcgg accgcgacgc ccggctctcc
    11761 tccgtgctgg acgtgctcta cctggtcttc aacgagggct acaccgccac gtccggtgcg
    11821 gactggacgc gcgcggacct gtgcgaggag gcgatgcgcc tgggccgggt gctcgccgcg
    11881 ctgctgcccg aggagcgcga ggtgcacggg ctgctcgccc tcatggagtt gcaggcctca
    11941 cggcttcgcg cccgctctgg gacggacggc cgacccgtgc cgctggccga ccaggaccgc
    12001 tcgcgctggg accggctcct gatcacccgg ggcctgcgtt cgctggcccg ctccgtgccc
    12061 cgtgaccccg ccgaaccgcg gggggcctac tcgctccagg cggggatcgc cgccgaacac
    12121 gcccgggccc tcggcgccga cgacaccgac tgggtcgcga tcgccctcct gtacgagcgg
    12181 ctcgtccggc tcacccggtc accggtggcc gagctcaacc gggcggtcgc tgtgtcgatg
    12241 gccctggggc ccgctcccgc gttggagatc gtcgacgcgc tccgggggat accggaattg
    12301 gcgggctacc accctctgcc cgccgtgcgc ggcgaccttc tggtccggct cggacgcagc
    12361 ggcgaggcgc gctcggaatt cgagcgtgcc gcggaactca cccgcaacga acgcgagcgc
    12421 gaactcctcc tggaacgcgc ccgatccggc tgatagcgaa ccccgtggat ccgttctgaa
    12481 ctgcggattc cgttgttccg ctacctacac tccgcgtgcc cgcccgcgcc actgacaaat
    12541 gtcatgcgtt tctgctggca tacctcagtt ctcaggggga caaggagttg ttagattctt
    12601 ctttattctg gagaaaagtc ttccgcgcga tgtactgaaa ggtgcggtcg gctcttctct
    12661 gtgtctttgt atggagagga agaagtgtcg gcgatcgaag tgaggaacat atcgaaggcg
    12721 ttccgcggcc accgtgcggt cgacggggtg tccttcacgg tggagccggg aacggtcacc
    12781 ggattcctgg ggcccaacgg tgcgggcaag accacgaccc tgcggtgcct gctcggcctg
    12841 gtccgccccg atcgcggtga ggggctgttc ggcggccgtc cctacgcgag cctgcccgcc
    12901 cccgcctccg aggtgggcgc ggtgctggag gccaacaacc tgcatcccgg gcgcagcggc
    12961 cgcaaccacc tgcgcaccct gtgcgacgcc gagggcctgc cgctctcccg ggcggacgag
    13021 gtgctcgacg aggtcggcat cgccgaggcc ggcggcaaac gggtcgccgg gtactcgatg
    13081 ggcatgcgcc agcgcctgtc cctggccggg gcgctgctgg gcgaccccag ggtgctgatc
    13141 ctggacgagc ccgccaacgg cctggacccg cggggcatcg actggctgcg gcgcttcctg
    13201 gactaccagg cgcacgagag gggcgtcgcc gtcctcgtct ccagccacgt cctggccgag
    13261 gtcgagcaga ccgtggacaa cgtcgtcatc atcgcccggg gccgactcgt ccaccagggg
    13321 accctcagcg aactcaccgg gggaggggag agcctgcacg aggccttcct ccgcctcacc
    13381 gaccaggaga actccgaaca gcccgtggga ggtagccgat gaccgcgctc gtcaggtccg
    13441 aactccgcaa ggtcttcacc acccggctgt ggtggatcat gctcctggcc gccctggcct
    13501 gggtggggct gtccctgggc ctcatcatcg tctccgccgg gatggagggg ggcttcgccg
    13561 ccgacagcgc cgagtacgcc ggggccgtct ggcccatggg tgcttcgggg accctcttcg
    13621 ccctggtcgt gggcatcgtg gtggtgactt cggaatacca gcaccgcacc gtcaacacca
    13681 ccttcctggt cagcccccgc cgactgcccg tggtcctggc caaggccgtg gccgcggccc
    13741 tggtcggcct gctgttcggc gcggtcgtgg tcgggctgtc cgccgtggtc gccggcgcct
    13801 ccatcctggc cgggggaggg gagctgaacc tggtcgacaa ccaggtgccg cgcgttctcc
    13861 tcggctccgt ggccgcccac gtcgcctaca ccgtgatcgg tgtgggcgtg ggcgcgctca
    13921 tccgccacca ggtcgccgcc ctggtggtcg gaatcctgtg ggtgttcatg ctggagccga
    13981 tcctggtggt cgtgccccag ctccaggacg tcggccggtg gctgcccggc ggtgcggtct
    14041 ccgccctcta cgacaccggg gtcgactacg gaatgggggc catggaactg ctgccggtgt
    14101 ggggcgcgtc catggtcctg gcgggctacg ccgcagtggc gatcgccctg gccgcggcca
    14161 ccacgctccg ccgcgacgtg gcctgagcag cacggggcgg ccgggctcag aacgcgggcg
    14221 ggcccggctg ccccgacagg tgcgggtcca cccgcccggt cacgtggtcc acggccatgt
    14281 tggcgtgcag ccgcgccccg gtgagcagga ccgagtcgtc ggcgtagaag gccgggttgt
    14341 ggttggccgc cgatccgcat cccatagttt ctgatcgacc cgaacgcgct ggatcggtgt
    14401 ctctgccacc ggtggtccct tcactgaccg tagacattgt gtccacggct gagtccctgg
    14461 ggcgggggct ccccgggaca gatcagcctc gttcacctac tgggttttgc gaacctcagc
    14521 gatgagtgct acccactggc tcagagggac cgtgacgtgt cccgcgtcgc ggtgggcggt
    14581 gtcgcgcaca tcggcgcctg acgcgtgttc ccgcacctcc acgcactcgt tgttgccact
    14641 gctgtacgag gacttgtgcc actcggcggt catgccaggt cacctctcac ttgctttacc
    14701 aggtccagag acgctgcggg ggtgagcgcc caggacatct gttctccgaa gatagcgccc
    14761 aagcgcctga cctcatcacg ctggtcgatg accacgcccc cagaagcgtg ctcggcatag
    14821 gccagaggca accgctcctc gaaggagatc agcctgaagg ggccggttgc cacccctgcc
    14881 cggttctccg ttcctgaggg gacgatcagt aagcggagag tcccatcggt ctggagcttc
    14941 agcaggtgat cgagctgttt tgcctgaatc tccggtgatc cgatcgtgtg cctgatcaca
    15001 tactccgcga gcaccacgag cattcttggg cggttctgag agagcagtct cggcagcatc
    15061 gaggtcctga tcttcatcag acgctcaacg ttggccgggt cgtcaccggg acgacagtcg
    15121 gtcagaacgg cacgtgcgta atcgggtgtc tggaatcgcc ccgggatgag tgccgagtgg
    15181 aatatctcga tactgatcgc gtacttctca gcctcggtga tctcgcgata ccactccggg
    15241 ttgtcgtcga gccgccgcgc ggtctcccaa gcccgtagaa cacctccgtg ggcgcccagc
    15301 tctctgtcca ggctctccac gtctctgcgt ctaggttttc ggtggcccgt ctcgtggccg
    15361 ccaagcgtgc ttctcgccat cccacaccgc ttggctagat cctcctgcga caacccagac
    15421 atattgcgca aatagctcag tttggcacca aattcacgcc aggcgtagtg aggggattca
    15481 gttgccatgc gagcactatg ccatagagat tgccgcgtca gctccgcaac gatgacgcag
    15541 aatgatgcat cactctcaca tcggccctga ttgtgcggca tctctggctt ctttcctgct
    15601 ccaagttcat gcttcctttt ggcggccgag agctgctgag tacttccgaa catgccgacc
    15661 agaggtgaga ggtgatctgt gtgggggaat cgattgagtt gcaggttgag ccccctgcgg
    15721 gttcagccga agtccttccg ccccctcagc gcgtgaccga cgaagcgatc cgcgctccga
    15781 tcgccacccc gggcgcacca ctgccgaccg gcgtcgctgt cgccgtggcc ggcgtgcccg
    15841 agcacgctca cctggtcagg cgactcgtac ggatgcgggc cggacgccct ccccgcgaag
    15901 cggaactcct ggacctgctg gtcaccgagc tgttcacgaa ctcggttcgg cacagccgca
    15961 gcggcggccc gggaggcagg gtcacgtctc cgtcgccaag aacggacagc gcacccaggt
    16021 caaagtggtc gaccaaggcc ccggccacgg aaccgtcccc tgcatccggc ccctcggcac
    16081 cgaggaggac ggccgcttcg gagggttcgg cctgcgtctg gtgaacgcct tcgcctcccg
    16141 gtggggctac gagagcggcc agaggcgcac aacggtgtgg ttcgaggtcg accgcctccc
    16201 ggggcggtga ccgccgtggc atggcacgtc gaggacgacc ggcccttcta cgcgaccgcc
    16261 cggcggctcc aacacgccgt cggctcacgc tgggtcgtgc tctggggacc ggccagccgc
    16321 cgctactggg ccttgccctg cggtaccgcc accgcgcccg tcctctccga ccccgatccg
    16381 gaccggctct acgccatggc acagcgacag gcggcaggcc gccctgcgac cggtactgcg
    16441 gcacccgcgc cctccgaaca ccgacagccc cgttgatccg gcgggaccca cacccacgac
    16501 accgacgatg agcggaaagc ggaccaggac gatgttctcc ctgtgcaggc actgcggcag
    16561 cccacgccaa ggcggggcac cggcctaccg atgcacctgc atcccctccc aggtgtggga
    16621 ggaacccgcg atggtccagg ccgtgcgcgc cctgaacctg tcggcggtga tccgcctcct
    16681 gcgccgccac ccgggcacca ggcacctgtc gcagcaacat cagcggcctg tcccagtcgg
    16741 ccgtctcccg cctggagaaa ggccgacacg ccaccaacat ccgccgctgc gtccaggcgc
    16801 tggaagcgct gggcgcaccc agatcggagg acgaggaccg gcccggaccg cgcggcaccg
    16861 gggcgcaccc gccttcggag gagtcccctg ccggtccggg ggtgccgtgc gtggttatca
    16921 cctgccccgc tccgatctac gtgcaggtgg tcgacccgag cagcggcccc gagaccgagc
    16981 cgcaccggaa ccgggccgag atcgccttcg tggccgatga gtccggtccg cggctggtcc
    17041 tcacccgcga caccacctgg ggcgtggaca gcaacgccaa cggtgccacc gcctggttcg
    17101 ccctgcaccc ttccgacagc cctgctctgg agcccgcccc ctccggccct gaaccccagt
    17161 cctagatcag cacggcggtg cacaacctcc catggcccat ctggggagcg cgccgtccca
    17221 tctctcccgc ttcgccccac tgcacgagag gtgttgggaa gaggcccatc cccatccgcc
    17281 cttcagcaag gtccgcgtgt tcgacgcact gcctcgcgct cctcccattc acggaggacg
    17341 cccacacaac aacacgacgt gaggagatct tgatggacgc cagcacgcag atcgcggacg
    17401 aggaactgaa cgtcgcggtc gaggagatcg ccgccgttcg ctcccgtgcc gagcagccct
    17461 cggacggggg cagcaccggc aggggcgaca ccaacgacgg catccgctag gagagcactg
    17521 tgaccgctga cctgatcagc ggccgtctgg gcggggacac cttccccgcc caggtgctcg
    17581 gccgcaccca ccgccactac ccggctcccg aggacgagcg ggatgccttc cggcacctgc
    17641 tcacctggtc ggacctgaac accctgctct cgtctcagcg cctggactcg cctcggatga
    17701 gactgtcagc gggtgaagtg atcgacgcgg gcgagtacac ccggctcagg cagtaccggc
    17761 gcatgcccga ctggaacgca ccggtcccgc acctgttcca ccagcggctc cgcgagggcg
    17821 cgaccctggt cttggacgcc atcgacgaga tgcacccgcc gatagggcgg ctcatcagcg
    17881 agttggaagc ctggctcaga accggcatcc aggtgaacgc ctacgcctcc tggacctcga
    17941 aggaggggtt cggggtgcac tgggacgacc acgacgtcat cgttctccag gtatcgggac
    18001 gcaaacggtg gcggatctac ggcaccaccc gaatcgcccc cttgcacgat gatgtggagt
    18061 tcgccgaaga agagcccacg gagatcatcg acgagttcgt catggagccc ggggacgtcc
    18121 ttcacgttcc gcgcggatgc tggcacgcgg tcgccgcctc cgagggcgaa ccgagtctgc
    18181 acctgacgtg cggtctggtg accacgaccg gcgtgaactt cctccgctgg ctcgtcaaca
    18241 agctgatcga gcacgacgaa gtcagggccc acattccacg agcgcccgat gagtacgcgg
    18301 cttggacacg acgtatctcc gagctggtga cagaccggct ccgagccccg gaagtagtgg
    18361 aagagtactg gcgccaccag gacgagacct ctccggcacg cggtcgccgt caccggcgag
    18421 ctggctccta ccgccgtcgt ccggttcgcc tccctgcgcg gtaccgtcac cgagaccggt
    18481 ggcgaggtgg tctactccgc ccaggggcgg cgctggcggc tcccggacaa ggtcgccccc
    18541 gtgatcactc acctgcacca cgctggtccc gcctcgatca aggagctgaa cgcgctggtc
    18601 cccagcgtgt ccgagaaggc gctgctcggc ctgttccgca ggctgatgga cgacggggct
    18661 ctggtcctgg agggcgaggc atgacggtca tcggcatggg gacctaccga agccgcgacg
    18721 ctgtgacgtc agcgagtatc gcggcttcgg acggttgtcc tctcatcgac accgcccctg
    18781 tgtacggggg cggcacgcac caggtcgcga tcgctcccgt gctgcgtgat catcctgagg
    18841 tccgggtctc caccaaggtg gggtacatga ccgagggaca ggcgcgggtc gcgttcacca
    18901 gcacagcgct gtctgaggag gaggcggcct tccgccacag catcgccccc gactacgtcc
    18961 gccaccaggt cgccatgtcg cgcacggaac tcaaacgaac ttcccccgac ctggtctacc
    19021 tgcacaaccc cgagcaccac catgaggaac ggggcgacct ccaccagcgc ctacgctcag
    19081 ccttcgcggt actggaagac ctgtacgcct cgggcggcat cggcggctac ggcgtgtcca
    19141 cgtggaacgg gttcgagtcc gggacgttca ccctcgccga tctcctccgc ctcgccgagg
    19201 aggcagcggg cggccccgag accggactgt ccgcgatcca gcttcccgtg tccatggtga
    19261 agatcgcccc cgtccatcag gccctcgcgg gaagcggtcc catcgcccag gccgacgagg
    19321 caggattgga ggtgtgggct tcggcgcccc tccacggagg agagctgttg cgtctgatca
    19381 acccgagcct ggctgaggcg gtacaccccg gagcgagccc tgtcgaggcc gcgttgaagt
    19441 tcgcctcgtc cgtaccgggg ctgacggggg tactgatcag caccaccgac agcgcgcact
    19501 acaagcaggc ggtcgaagcg atccgagagc ccctgcccga ccatcgactc aaggaactct
    19561 gtgacgtcct cgccccgcct tcccgatgat ctgaccgacc ggtggcatca cgcggccgag
    19621 agcctgaaga gctctgccgc tgccgacgtc cccctgtgct ccgggctggg aggccggacc
    19681 ctgagcggcc cagtgacggc ggccgatgga cacccggcct ggctgcgatt gatcgccgca
    19741 tcccggccag gggggaagat ctgggagggt gcggcgctcg cggacactct gctggacgag
    19801 gcgattcctc gcccggtgat gctcggcgaa cacacctggc aggaagaggg ggcggcgttc
    19861 caagccaccc tgtggacacg ccttcgggga gaggtcctct ctcccacccc ggacctgtcg
    19921 actccggtcg acgtggacga ccgttggtgg aagagcctgc gcacctgggt ggagaaggtc
    19981 cgcagtaccg cggtgcctcc gggcagggaa gtgatgacgc aggcgtacat cgaccggatt
    20041 ccccggttca tccccgtgtt ggagggcgcg gacctgaccg tgccccgctg ggagtccgcg
    20101 cacggcgacc tccactgggg caacatcacc ggtgatccac tggagatcat cgactgggag
    20161 ggctgggggg cggcaccggc cgggtacgac gcggccgtcc tcctggccta cgccctgccc
    20221 gccccggcca cggccgcgaa agtccgtgag gtgttcggcg acatgctgaa caccggcccc
    20281 ggccgtctcg cccaactggt gatctgcgcg gagatcatcc aggcgtcgga gcgtgacgac
    20341 ctccacgcgc gcttgaggcc ctacgcggaa aggctcgccg ccgacgtact cgctccgcag
    20401 tagtcgcacg tcgcggggcc tcgctcggtg atccgggtga ggcccttcgt cccgcactgc
    20461 ggacaccgct cggagagccg ccgaaccccc agcagcggca ccagcgccag gcgggcggca
    20521 cgggtgtccc tgcctgagcc gcgcggggcg gccgggctca gaacgcgggc gggcccggct
    20581 gccccgtcag ggccgggtcc acccgcccgg tcacgtggtc cacggccatg gtggcgtgca
    20641 gccgcgcccc ggtgagcagg accgagtcgt cggcgtagaa ggccgggttg tggttggccg
    20701 ccgatccgcg ctggccgggg attgagcgca gggccccgtg ggcgtactcg gtgtcctggc
    20761 agccgagcat cacgtagacg ccgccgaagg cccggacgaa ctccgacacg tcgtcgtacc
    20821 cgaggctggg ctcggtctgc ttgacccggt cctcacccac cacccggcgc agggtgggca
    20881 gcgcggccga cgtccactcg ggggtgttgt ccaccgcggg cacgtcctgg aggaactcgg
    20941 cctccgcggt gcagccgtgg gcctgtgcgg tgtgctcggc ggtgcggcgc aggtggtccc
    21001 gcacggtgtc catgtccccg tcgtgcaggc agcggatcgt cccccacagg gtgaccgtct
    21061 caccgatgat gttgaaccgg ccctggtcct ccacgtggcc gatggagacg gtgaccggtg
    21121 aggtggcggg gatccgccgg tagatctgcc cgcaggcgga gacgatgtcg gccgccggcg
    21181 gcatggggtc caggcccatc cacggcatcg aggcgtgcac ctgcttgccg tggacggtga
    21241 tccgcaccat gcaggacgcg gcgtactggt ggcccgcccg gtagcccacc acgcccttgg
    21301 gcagcgggac gacgtgcagg ccgaagacca tggtgggggc cgggtcgcgc agggccggag
    21361 agccgaccat gctgcgggcc ccgccctcct cggccaccgg agggccctcc tcggcgggct
    21421 ggaagacgaa cagaacggtg cccggcaggt ccgagcgcat accggccagg acctccgccg
    21481 cacccatcac catcgcggtg tggcagtcgt ggccgcaggc gtgcgccacg gggaaggggc
    21541 cgccggggta gtccgcgtcg accgcggtgg aggcgaagcc gacaccgctc tcctccttga
    21601 ccgggagggc gtcgatgtcg gcgcgcagcg ccgccacgcg gtccccgccg aggccgccgc
    21661 gcaggacgcc gaccacgccg tggccggcca cccccgtgcg cacctcgtcc agccccagtg
    21721 agcgcaggtg ctcggcggcg aaggcggcgg tctccgcctc ccggttgggc agttcggggt
    21781 gcgcgtgcag gtggtggcgc cacgcgacga tcttggactc gatcgccgcc gcccgccggt
    21841 cgacggcttc gtgcagcggg gccacatccg cgatggtcgt cccggtcatc gtccctcccg
    21901 gtgctcgctg tggccaccgt aggcaggacc tcccccacga tgggtgtaaa cgcgggcaaa
    21961 tcctcaccac gctcccacac ccgcggtgac ctgggagccg agacctaccg ggcgtaccgc
    22021 ttgagttcgc cggtgctcag cacgatcccg gtacccggga tctcgaccgt gtggccgtag
    22081 ccgagcgtgg tgatgctccg gtagcggccg tcgacgggct cgccgtgcac ggtgacgctg
    22141 tcgtcgtcgc ggtcgatgag caggtagacg ccgatgccgc aggcggcgta ggcctgcgcc
    22201 ttctccaccc ggtcccgggc gttggtgtca acgtcccagg aggtcgcctc gacgaccgcg
    22261 aggactccgc ggggatcggc ccattcgccc tgaccgatga agtggtcgac gggggccagg
    22321 agaccgtccg gccggacccg gcccttgcgg taggcgtcca ccttcaggcc ctgcccggtg
    22381 acgttcaggt ccaggtccgc ccgctgggcc atgcattgac gcgtcaacca catgaggatc
    22441 gcgttgtggt cgctgtcggg cacggtccgg atctccatct caccgttgag atattcgagg
    22501 gtgacgtcct cacgagccgc ggcctgggcg atgacctcga actgtgcgac gctgagcttc
    22561 tcgacagggg atctgggcga ggagtgctcc atcacggtca tggcgatatc cccttcaggc
    22621 tggatacggg cgccgactgc gcgtcgcgga gtccggaatc cagcgtacaa gaggcggctc
    22681 ccgcccactc ccttcacaac gtgacatccg aacatcatga tgtgcctatg agaacgacga
    22741 tcgagatccc ggacgacctg taccggcagg cactgtccat cgccgaggac acatcgcgct
    22801 cactcggtga gacggtcacc gaactgatgt gtcgtgggtt gggccagaac ggcggtgctg
    22861 ggggtatttc ccggagcgcc aggaccgggc tgcccgtggt ccacctgggc acggtcatca
    22921 cgaccgggga ggtccgggcc cttgcggacg acgatcttgg ccggatgtcg accgggcata
    22981 ccgtgtgagt tctgcggtca gaccgtaccg gcggggacga tccacagggt gggctggccg
    23041 gtgaccgccg agatgaggtc gtagtccttg ccgtagtgga cgaccgtcgc cccgtgggcc
    23101 tcggcggtca cggcgatgat gaggtcgggc agcgcgcggc ggtgctgtcc ctttcccggt
    23161 agggccgggc cggggcgcgg ccgcaggcgg tggattcggc cgaccccggg cacacacgtg
    23221 gggcccgccc cgggacgggc cccgcaccgc tcggtcacag ctccggttcg acggccttcc
    23281 tgcgacccac gctcagccgg tcggcggtct cctccacgtc cacctccacg gtgtcgccct
    23341 cggccagttc gcccgagagc agctcccggg ccagcgggtc gccgatggcc gactgcacca
    23401 ggcggcgcag cggccgggcc ccgtagttgg ggtcgtagcc cgccagcgcc agccagtcgc
    23461 gggccgccgg cgtcacctcc agccctaggc gccggtcggc caggcgccgc gccagcttgt
    23521 ccacctggag gtcgacgatc cgggtcagct cctccgtgga cagcgcgtcg aacatgatca
    23581 cgtcgtccag ccggttgagg aactccggct tgaacgtcgc gcgcaccacg tccatcaccc
    23641 ggttcctgcg ctgggactcc tccagcgacg ggtccaccag gaactgcgat cccaggttcg
    23701 aggtgaggat gaggatggtg ttgcggaagt ccacgtggcg accctgacca tcggtcagcc
    23761 gaccgtcgtc caggacctgg agcagggtgt cgaacacctc caggtgcgcc ttctccacct
    23821 cgtccagcag caccaccgtg tacggcctgc gccgcaccgc ctcggtgagc tggccgccct
    23881 cctcgtagcc cacgtatccg gggggcgcac ccaccagccg tgacaccgag tgcttctcgg
    23941 agtactcg
//
