LOCUS       NZ_KI911536            22637 bp    DNA     linear   CON 21-OCT-2024
DEFINITION  Nocardiopsis sp. CNT312 B042DRAFT_scaffold_0.1, whole genome shotgun
            sequence.
ACCESSION   NZ_KI911536
VERSION     NZ_KI911536.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nocardiopsis sp. CNT312
  ORGANISM  Nocardiopsis sp. CNT312
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsidaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 403132)
  AUTHORS   Jensen,P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R41043
            investigation_type                :: bacteria_archaea
            project_name                      :: Nocardiopsis sp. CNT312
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi14643
            Funding Program                   :: DOE-CSP-ICBG 2011
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000515115.1-RS_2024_10_21
            Annotation Date                   :: 10/21/2024 21:26:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,296
            CDSs (total)                      :: 4,234
            Genes (coding)                    :: 4,144
            CDSs (with protein)               :: 4,144
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 23 of 90
            Pseudo Genes (incomplete)         :: 74 of 90
            Pseudo Genes (internal stop)      :: 5 of 90
            Pseudo Genes (multiple problems)  :: 12 of 90
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:21:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 13729
            Orig. end                         :: 36366
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KI911536.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 407425
            Source DNA and Organism available from Paul  Jensen
            (pjensen@ucsd.edu)
            Source DNA available from Paul  Jensen (pjensen@ucsd.edu)
            Organism available from Paul  Jensen (pjensen@ucsd.edu)
            Contacts: Paul  Jensen (pjensen@ucsd.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22637
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12637](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12637
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            2049..2525
                     /gene="dut"
                     /locus_tag="B042_RS0117025"
     CDS             2049..2525
                     /EC_number="3.6.1.23"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="dut"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019608277.1"
                     /locus_tag="B042_RS0117025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dUTP diphosphatase"
                     /protein_id="WP_028649322.1"
                     /transl_table=11
                     /translation="MSTSSLAGGPIAVTVHRLDPGLPLPEYAHPADAGADLCTAVDVEL
                     APGERGTVPTGLAIALPEGYAAFVHPRSGLAARCGLTIVNAPGTVDAGYRGEIRVTLVN
                     TDRETPVRLSRGDRIAQLVIQRVERAEFVEADSLPESVRGTGGFGSTGGHAALR"
     gene            2584..3393
                     /locus_tag="B042_RS0117030"
     CDS             2584..3393
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017598330.1"
                     /locus_tag="B042_RS0117030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3710 domain-containing protein"
                     /protein_id="WP_028649323.1"
                     /transl_table=11
                     /translation="MFGRRRKKQDEETGTTDAPRRSTTGEEVSFGNVVEPEKSSASADK
                     ESDRHRATGPWDVSEEPSEAKRMDLGSLRLPMEQGLQIQVNVARDDRGKQTIIGVTLVK
                     GKSSLQVQPFAAPKSEGLWEDMRRELREQVAKQGGNSHEHDGTFGPELQAVVPVKGKKT
                     EDGKQIAQRVRFIGVDGPRWVLRGVVRGEGAARPEAMGEIERLFADIVVVRGEQPSPPG
                     ELLQITVPKQLQEQMAAAQARAAHQAAQSGNAGRSPNGSAPGGPDGA"
     misc_feature    complement(3434..3444)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    3435..3445
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            3439..4179
                     /locus_tag="B042_RS0117035"
     CDS             3439..4179
                     /EC_number="3.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017544994.1"
                     /locus_tag="B042_RS0117035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIG-L deacetylase family protein"
                     /protein_id="WP_028649324.1"
                     /sec_met_domain="PIG-L (E-value: 4.9e-24, bitscore: 80.0,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQTKDSNAPRPLPEDWDRALAVVAHPDDLEFGASSAIARWTGQG
                     KDVVELMATRGEAGIDTIAPHECGPLRVAEQRASAAEVGARDVEFLDFPDGTLEYGLPL
                     RRALAEAIRRHRPEVLVSINFREAFPGGTSFNHADHRVLGPALLDAVRDAANRWVFADQ
                     LDGGLRPWAGVRFAAFGASPRPTHYVELSEADLAAGIASLDRHGVYLAHLEGFDQKAFL
                     STAAREAGGRAGTALATEFEVFDT"
     gene            complement(4188..5279)
                     /locus_tag="B042_RS0117040"
     CDS             complement(4188..5279)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017610510.1"
                     /locus_tag="B042_RS0117040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serpin family protein"
                     /protein_id="WP_028649325.1"
                     /transl_table=11
                     /translation="MHTPVRRDHLEFAAALDRALARPRASHVWSPYSVGTVLCLLAAGS
                     SGGTRDELESLLGADPHALLTSLDGAAGAQEGPELAAFNGLYIPDGLAVRPAFTELVRA
                     RPAAEVRGADVRGDPEGVRRRINAKAAEATRGLVPELLPPGSVGPDVRMLLANALWAKV
                     VWACPFEVRATRARRFHAPGGDRTVPAMHREGDLTFARARGWRMVSLRGEHDLALDVLL
                     AQGRDAVPDADTLEALYRARRRTPVRLALPRFAVRTGTGLLEPLARLGVRTLATDAARF
                     DGISGEPLKVDALLHQAVMRVDEKGAEGAAATAAVMVRAAAAPTRPVDFTVDRPFSFAL
                     RRGGTLLFLGRVADPEDPGPARG"
     misc_feature    complement(5331..5346)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.65"
                     /tool="antismash"
     gene            5526..6332
                     /locus_tag="B042_RS23680"
     CDS             5526..6332
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017614555.1"
                     /locus_tag="B042_RS23680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3159 domain-containing protein"
                     /protein_id="WP_036555507.1"
                     /transl_table=11
                     /translation="MTEQRRAAEEAARAAGADDGGPKVTEDTVEALVRSQLAKVLGGKR
                     GMVEAAVPTLAFTLSYIVLSRIDGALTLFGGTYSDLRVAITAGVVAALVLGAVRLVQRS
                     TVQYVVTSLFGIGIAAVFAMRSGEAADAFLPGIIYNAVYAVVLTLSILVRWPAIGLMIG
                     PFIGDKEDLTSWRADPAVVSLAAKLTWLLVLPCVIRVLVQYPLWFMDHYDIADTFALLG
                     LAKIGMGWPLQVAGLAAMVWVLARGRTPLRQGPDGEAGRGGGGGRG"
     gene            complement(6348..7031)
                     /locus_tag="B042_RS0117050"
     CDS             complement(6348..7031)
                     /GO_process="GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013153893.1"
                     /locus_tag="B042_RS0117050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TrkA family potassium uptake protein"
                     /protein_id="WP_028649326.1"
                     /transl_table=11
                     /translation="MRIAIAGAGSVGRSIAAELAASGHDVLLIDRDTRAIDVDDLTQVE
                     WLLADACELASLEEARLGEADVVIAASSDDKVNLVVSLLAKTEFGVDRVIARINEPDNE
                     WLFNDSWGVDLAVSPPRLIADLVEDAGEDGFAEEETPPLPGAEIAESVLHAESAFVGGP
                     ESALTSRLPEGVALVAVVGSGGVRAPGSERTLAVGDTVVFLAEPGALETLEGLLGPADG
                     SDGDV"
     gene            complement(7033..7698)
                     /locus_tag="B042_RS0117055"
     CDS             complement(7033..7698)
                     /GO_process="GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017581032.1"
                     /locus_tag="B042_RS0117055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TrkA family potassium uptake protein"
                     /protein_id="WP_028649327.1"
                     /transl_table=11
                     /translation="MHIVIMGCGRVGSTLAHTLVDLGHTVAVIDQDPEAFRRLRGAVTK
                     HAVRGVGHDREVLLAAGIEHASAFAAVSNGDNSNIISARVARETYGVEHVVARIYDPRR
                     AEVYQRLGIPTVGTVRWTADTILRRMVPGDQRLTAGPEWHDASGTLAMNEVTLPRTWAG
                     RRVSDLESRTPVRVVYVARGGGILLARSDLPLEAGDILHVVARGRDLDALRSDDETGH"
     misc_feature    complement(7683..7697)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            7918..9210
                     /locus_tag="B042_RS0117060"
     CDS             7918..9210
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017581033.1"
                     /locus_tag="B042_RS0117060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="WP_028649328.1"
                     /sec_met_domain="PCMT (E-value: 3.2e-07, bitscore: 24.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATRVGDEFELTVNDAAHGGWCVGRHHEQVVFVRHALPGERVRVR
                     VTERTSRFLRGEAVEVLEASPDRVEAPCPFAGPGRCGGCDWQHASLAAQRVIKGRVVAD
                     QLRRIAGTDREVTVEELPGSPDGLGWRTRVRFTVDAHGRAGLRRHRSHDVEPVDRCLIA
                     HPGVEELGITDVTWEGVRDVEAVASASCADRAVVVTPSGSKLGPLPDLKASSAVLRRFK
                     GGRVQQVRGRRGVRETVAGREFRVGAGGFWQVHPAAGEVLTGAVMDALAPREGETAIDL
                     FCGAGLFTAPLAEAVGPQGRAMGVEGAVEAVRDARYNLKDLEQVRIEHGDVAAQLREWA
                     DVRADVVVLDPPRAGAGAEPVRLVAGMRPRAVAYVSCDPATLARDLASFEREGYRLTAL
                     RAFDAFPMTHHVECLAVLEPVRPARRHRERA"
     misc_feature    complement(9297..9310)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.2"
                     /tool="antismash"
     misc_feature    complement(9300..9314)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(9301..9316)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    9413..9427
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.78"
                     /tool="antismash"
     misc_feature    complement(9522..9535)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.98"
                     /tool="antismash"
     misc_feature    complement(9524..9540)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.68"
                     /tool="antismash"
     misc_feature    complement(9597..9611)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.75"
                     /tool="antismash"
     misc_feature    9655..9669
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.52"
                     /tool="antismash"
     misc_feature    9659..9674
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.14"
                     /tool="antismash"
     misc_feature    9664..9673
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.35"
                     /tool="antismash"
     misc_feature    9927..9947
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            10001..12637
                     /gene="lanKC"
                     /locus_tag="B042_RS0117065"
     CDS             10001..12637
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017559021.1"
                     /locus_tag="B042_RS0117065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_028649329.1"
                     /sec_met_domain="micKC (E-value: 2e-227, bitscore: 751.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.8e-14, bitscore: 48.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.4e-06, bitscore:
                     20.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRGYGVFCDADRYFYDTPHRLWSGSGADDGRGPVFEAARRPVPE
                     GWQSHRAGDWLALRPVEPRLPDQGWKIHVSACLDNAESVLGRVWDYCVARGVSFKFVPT
                     RYLLHNRNAKYADRGGSGKFITVYPADDGECASVAAGLDALVGGEPGPYVLSDVRWNAG
                     PVHLRYGSFTRRHCYDKHGDAVPALENAEGVLVPDHRGPVFRLPEWVPVPDFLRPHLEA
                     RGAVDVTGLPYDIERALHFSNGGGVYAGRDRRTGESVVLKEARPHAGLAADGADAVRRL
                     EQERTALERLAGLPCTPEVKDAFTLGDHHFLVMEYIEGKPLNSFFARRHPLVEADPAPD
                     ALRDYGRWAMRVHGLVSEAVRAVHERGIVFNDLHLFNIMVAEDESSVVLLDFEAARDAG
                     QDSRQTVANPGFVAPRGRRGFDVDLYALACLRIALLLPLTSVLAMDRSKVRHLAEEAAR
                     VFPEAREFLEAGVTEILRDPDDGTGAPPAATGVHGPYLPAEPGDWPRGRDSMVRAILAS
                     ASPDREDRCFPGDIAQFTTVGGGLSFGYGTAGVLYALAESGAPRCPEAEEWLLRHSKEP
                     DSGFPPGFFDGLSGLSWVLRRLGYGQPSLALAELVLAQPWEGLGPGLHSGTAGIGLALD
                     SLAADTGDPEAAAGALRCAELAVHGFLGAPPERRRAGLLYGGAGVALLCLRLYERTGDT
                     GLLDSAERALRADLDRCVTSAFGTLQVDEGWRTMPYLGAGSVGVGIVLDDYLEHRADEE
                     FERARPEIAGAARSGFYAQPGLFRGLAGMVLYLSRTTAPGTGAGDVHRQVDALSRYAMR
                     YRGHLAFPGEQLMRLSMDLSTGTAGCLLALTAARGAPAQLPFLPPLRRTQSRATAMARN
                     KEEKKNE"
     gene            12658..12783
                     /locus_tag="B042_RS0117070"
     CDS             12658..12783
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017580486.1"
                     /locus_tag="B042_RS0117070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_028649330.1"
                     /transl_table=11
                     /translation="MTLFDLQSLETAKDEAHGEATATSTASLLLCGDSSLSVTTC"
     CDS_motif       12658..12720
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLFDLQSLETAKDEAHGEAT"
                     /locus_tag="B042_RS0117070_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12721..12783
                     /prepeptide="core"
                     /locus_tag="B042_RS0117070_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="15.30"
                     /molecular_weight="1768.0"
                     /monoisotopic_mass="1766.9"
                     /core_sequence="ATSTASLLLCGDSSLSVTTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLFDLQSLETAKDEAHGEAT"
                     /leader_location="[12657:12720](+)"
                     /alternative_weights="1786.0"
                     /alternative_weights="1804.0"
                     /alternative_weights="1822.0"
                     /alternative_weights="1840.1"
                     /alternative_weights="1858.1"
                     /alternative_weights="1876.1"
                     /alternative_weights="1894.1"
     misc_feature    12926..12935
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            12939..14696
                     /locus_tag="B042_RS0117075"
     CDS             12939..14696
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017580487.1"
                     /locus_tag="B042_RS0117075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_028649331.1"
                     /transl_table=11
                     /translation="MVPTRPRDGTADGGAARSADALLTRMVRASAGRTAGILLCAAAAA
                     AASLALPALLGLTLDLLLEGHPDAGRALAAVVVLTAAEVGLDAAVALLSGTVGARSTAW
                     LRLRAVRRLLAAAPRDVSRFSNGDVATRLSAHATEAGAAPAGAAQIVAAVLAPVGALVA
                     LFVIDPWTGLAFVLGLPVLGLLLRSFARHSSDTVSRYQRVQSLIATRLTDALGGARAIA
                     AAGTLEDERARVLSPLADLGVEGRRMWSVHGSAMARSGVLMPLLITAVLAVGGVGLAHG
                     RISVGDLLAVSRYAALAAGLGSVAGPLAALVRGRTAARRVGALLAVPPLAHGRAQLPPA
                     GPGTLELRGVGVNTDGVWVLRGVDLRVPGGRTVAVVGRSGSGKSTLGAVAGRLLAPDEG
                     EVCLDGVPLDTVAADVLRREVVYAFERPELQGATIADAIAAGARTAPDEGVRSAARAAG
                     ADGFVRALPLGYATPLEEAPLSGGELQRLGLARAFAHAGRLMILDDATSSLDTATERQV
                     DRALAHEVRPGTRLVIAHRLSTAARADLVVWLEDGRVRAVRTHAELWRDPDYRAAFGRT
                     DASGHREER"
     gene            14804..16543
                     /locus_tag="B042_RS0117080"
     CDS             14804..16543
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017597752.1"
                     /locus_tag="B042_RS0117080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_051415784.1"
                     /transl_table=11
                     /translation="MPHARPFLWRHRRVLLRLGAWSLVESVQTFLVGICLARALDQGFL
                     AGRTATGLAWLAVAAGSILLAGPVLRGVFGQLSALVEPLRDGLVRRAVGQALRRAVADP
                     ARAARVERAAVSRLTQQTEIARDSFAGLVLTVRSFLFTAAGALVGMLALAPELLLVVVP
                     PMLVGLALFLCTLAPMAAAQRRFLDADEAFTERAGALRGQLRDLVACGATDAAAQRAGP
                     LVDDAAASTRSLARWAAVRTLALGTAGQLPVVLLLVATPWLLDQGVTTGALMGALAYLV
                     QSLMPALQTMMTAVGAAGSRLVVVLDRFVSAEADGADGGGVPHEEADGPVLATPPAPEG
                     VPAVWCRGVRVSYGAGTRPLVEGLDLSVEAGERIAVVGPSGIGKSTLAHVLSGLHPPDE
                     GDVRLAGRPVAGRSPRELARERVLLPQRGYVFAGSVRENLAQLEPGAGDDRLAGAVAAL
                     RLGPLVDRLGGLAAEVDPGALSAGERQALCLGRAYVSRAPLLILDESTCHMDPVAEAHA
                     EEALAARPGTTLIVIAHRLSSALRADRILVLDGAGTALGTHGALLRSSPLYRDLAGHWN
                     ASV"
     gene            complement(16582..17688)
                     /locus_tag="B042_RS23685"
     CDS             complement(16582..17688)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017598321.1"
                     /locus_tag="B042_RS23685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DMT family transporter"
                     /protein_id="WP_231494132.1"
                     /transl_table=11
                     /translation="MSTTPTAPAPRRGLARGPLPVLGAALLWGTTGTAASFAPAGAHPA
                     AIGSAGLAVGGLLLLFTGRGYPALLHGADRRTRGALALGALAVAGYPLAFYPAVAQAGV
                     AVATVITLGSAPVFAGLLAWLSEGVRPGCRWSAATLAAVAGCTLLVLGAEGGDGARTVD
                     TSGVLLALAAGASYALYAVVSAAQIRRGHPSGAVMGVLFAGGGLVTAPVVLALDPVWLA
                     TGRGAAVALYLALFTVFLAYTLFGVGLRHTPAATATTLSLAEPAVAALLGVSVVGERLS
                     PAAWTGMAVLALGLAVLRTPSGRRPGRTRRNHRTEAGTRAPPAPRAGADTPPPGHPPAT
                     PPPQGARSGSALAASPGIAGHPSYSQLG"
     misc_feature    17765..17781
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.34"
                     /tool="antismash"
     misc_feature    17770..17783
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.01"
                     /tool="antismash"
     gene            17851..18748
                     /locus_tag="B042_RS23690"
                     /pseudo=""
     CDS             17851..18748
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017605309.1"
                     /locus_tag="B042_RS23690"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="LLM class flavin-dependent oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MREDKLLRLRIFIGPRQGAGTSSPSPGRRRTWAWTPCSAGNKELP
                     EWGLGSRLLRASVPATTRTWAAAPPDRPVPPTHGSPSRHWRGRPPGPAWTHS"
     misc_feature    complement(18828..18845)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.52"
                     /tool="antismash"
     gene            19115..21829
                     /gene="acnA"
                     /locus_tag="B042_RS0117095"
     CDS             19115..21829
                     /EC_number="4.2.1.3"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="acnA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019608289.1"
                     /locus_tag="B042_RS0117095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aconitate hydratase AcnA"
                     /protein_id="WP_028649334.1"
                     /transl_table=11
                     /translation="MSANSFGARDTLRVGDESYEIFRLESVEGADRLPYSLKVLLENLL
                     RTEDGANVTADHIRALGQWDPKAQPNQEIQFTPARVIMQDFTGVPCVVDLATMREAVRD
                     MGGDPDKINPLAPAELVIDHSVVVDLFGRPDAFERNVEIEYERNYERYKFLRWGQTAFD
                     EFKVVPPGTGIVHQANIEHLARVTMSRGGQAYPDTCVGTDSHTTMQNGLGILGWGVGGI
                     EAEAAMLGQPISMLIPRVVGFKLSGQLAPGTTATDLVLTITEMLREHGVVGKFVEFYGE
                     GVSSVPLANRATIGNMSPEFGSTAAIFPIDDETIRYMKLTGRSAEQVALTEAYAKANGF
                     WHDPSAEPQYSEYLELDLGRVVPSIAGPKRPQDRIALSEAKPTWRHDVQNYVADDEAGE
                     ESFPASDAPAQSADGRPSRPVKVTMADGTETEIDHGAVVIAAITSCTNTSNPSVMLGAA
                     LLAKKAVEKGLSRKPWVKTSMAPGSKVVTDYYERSGLTPYLDKLGFNLVGYGCTTCIGN
                     SGPLPEEISKAVQDNDLAVTSVLSGNRNFEGRINPDVKMNYLASPPLVVAYALVGSLDV
                     DITTEPLGVGKDGTPVHLADIWPSAEEIQEVMDAAIASDMYESAYADVFAGDERWRSLP
                     TPTGNTFEWEGGSTYVRKPPYFEGMAATPAPVTDITGARVLAKLGDSVTTDHISPAGAI
                     KPGTPAAEYLKANGVERRDFNSYGSRRGNHEVMIRGTFANIRLRNQLAPGTEGGYTRDF
                     TQSDAPVSFIYDAAQNYAAQETPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVITESYE
                     RIHRSNLIGMGVLPLQFPEGQSADSLGLTGEETFSITGVTELNEGRTPSTVKVATDTGV
                     EFDAVVRIDTPGEADYYRNGGILQYVLRQLTAK"
     gene            21970..22263
                     /locus_tag="B042_RS0117100"
     CDS             21970..22263
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS0117100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028649335.1"
                     /transl_table=11
                     /translation="MRGWANPLHGTDTRQVQWRESGGDRSVRVPLWRERAAAARKRARP
                     TVPTDEHVGRGVPYYEVPARKSVWAATGYGTPAGGLVRRIQRGDHRRASDTR"
ORIGIN
        1 tggaggaccg cgagcggccc agcgcctacc accggctggc cttccaccgg cccgacggca
       61 ccccggtcca catcgagacc acgcgccccg aactgctcgc ggcctgtgtg gccctggtcg
      121 cccaccccga cgacgagcgc taccaggacc tgttcggcac caccgtgcgc accccggtct
      181 tcggcgtgca ggtcccggtt cggccgcacc gcctcgccga ccccgagaag gggtccggta
      241 tcgcgatgat ctgtaccttc ggcgacatca ccgacgtcac ctggtggcgc gagctccagt
      301 tggagacgcg cccgatcatc gggtgggacg gccgcatcat ggccgaggcg cccaaggggc
      361 tggactccga gcgaggccgc gaggcctacg cgcggctcgt gggcgccacc gtccacaccg
      421 cgcgcgagcg caccgtcgaa ctgctccggg agagcggtga tctcgtcggt gagcccacgc
      481 cgatcaccca cccggtgaag ttctacgaga agggcgacaa gcccttggag atcgtcacca
      541 cccgccagtg gtacatccgc aacggcggcc gtgacgcgca gttgcgcgag gcgctcctcg
      601 ggcgtggcag gcagctcgcc tggcaccccg agcacatgcg ctcgcggtac gagaactggg
      661 tcagcggcct caccggggac tggctcatca gccgccagcg gttcttcggt gtgcccttcc
      721 cggtctggta tcccctggac tccgagggca acccgcgcta cgacgagccg atcgtgcccg
      781 gcgaggacca gcttccggtc gaccccagct cgcaggcgcc cgagggctac accgaggacc
      841 gccgcggcca ggccgggggc ttcatcgggg accccgacgt catggacacc tgggcgacct
      901 cctccctcac cccgcagatc gcctcgggct gggagcgcga ccccgacctg ttcgagcgcg
      961 tcttccccat ggactaccgg ccccagggcc aggacatcat ccgcacctgg ctcttctcca
     1021 ccgtggtccg cgcccacctg gagaacggca cactgccctg gagcaccacc ggtatctccg
     1081 gctggatcct ggacccggac cgcaagaaga tgtccaagtc caagggcaac gtcgtcaccc
     1141 ccatcgccct gctggagaag tacggctccg acgcggtccg gtactgggcg gccagcggcc
     1201 gcctgggcac cgacaccgcg atggacgagg gccagatgaa ggtgggccgc cgcctgtcca
     1261 tcaagatcct caacgccagc aagttcgtca tgtcggtggc gggcggggac gcctccaccg
     1321 acccggcccg gatcaccgag cccctggacc gggcgatgct ggccgccctc gccgacgtgg
     1381 tggaggaggc gaccgccgcg ttcgccgcct acgaccacac ccgggcgctg gagcgcaccg
     1441 agcgcttctt ctgggacttc tgcgacgact acctggagct ggtcaaggcc cgcgcctacg
     1501 acgcctcctc cgccgagggc gcctcggcgc gctccgccct gctcatcgcc ctgggtgccc
     1561 tgcaccggct cttcgccccc ttcgtgccct tcgtggccga ggaggcctgg agctggtggc
     1621 gggagggctc cgtgcacgcc cagccctggc cggaggcggc cgagtaccgc gccgcggccg
     1681 ccgacggcga cccggccgtc ctggcggtca cggccgaggt cctgcgcgcc gtgcgcaagg
     1741 ccaagtccga ggccaagctc tccatgcggg ccgaggtcga gcacgtcagg gtctccggca
     1801 agcgtgtcgg ggccgcccgt gccgccgcgg gcgacatcgc cgccgcgggc cgggccgccg
     1861 ggatcgactt cgaggccacc gacgaggccg aactgaccgt cggtgtgacg ctcccggacc
     1921 cggtcgggta ggggaccggt acaccagggc tcggcggggc ggggcggcga ggagccgctc
     1981 ccgcccctcc ggcgttcgac ggtgccggaa accggcagca ctcaccgggg gcgataagct
     2041 cagcggttgt gagtacctca tccctggccg gcggtccgat cgccgtcacg gtccaccgcc
     2101 tggaccccgg ccttcccctg cccgagtacg cgcatccggc ggacgcgggt gccgacctgt
     2161 gcaccgccgt cgacgtcgaa ctcgctcctg gggagcgcgg cacggtccct accgggctgg
     2221 cgatcgccct gcccgagggg tacgcggcct tcgtccaccc caggtcgggg ctggcggccc
     2281 gctgcggtct gacgatcgtc aacgcgccgg gcaccgtcga cgccggctac cgcggcgaga
     2341 tcagggtgac actcgtcaac accgacaggg agacccccgt gcggctgtca cggggggacc
     2401 gcatcgcgca gctggtgatc cagcgcgtgg agcgggcgga gttcgtggag gcggactccc
     2461 tgccggaatc ggtgcgcggt accggcggtt tcggttcgac cggagggcac gccgctctgc
     2521 ggtgaggagt ccccagagcc cggatgcgac ccgggagcaa cctagagcgt gagaggtgag
     2581 ggcgtgttcg gacgccgccg taagaagcag gacgaggaga ccgggacgac ggacgctccg
     2641 cgccggagca ccaccgggga ggaggtctcc ttcggcaacg tcgtcgagcc cgagaagtcg
     2701 tccgcgtcgg ccgacaagga gtcggaccgg caccgtgcca ccggtccctg ggacgtctcc
     2761 gaggagcctt ccgaggccaa gcggatggac ctgggcagcc tcaggctgcc gatggagcag
     2821 ggcctgcaga tccaggtgaa cgtcgcccgc gacgaccggg gcaagcagac gatcatcggc
     2881 gtgaccctgg tcaagggcaa gagctcgctc caggtgcagc ccttcgccgc gcccaagagc
     2941 gagggcctgt gggaggacat gcgccgggag ctgcgggagc aggtcgccaa acagggcggc
     3001 aactcccacg agcacgacgg caccttcggc cccgaactcc aggcggtcgt gcccgtcaag
     3061 ggcaagaaga ccgaggacgg caagcagatc gcccaacggg tgcggttcat cggcgtggac
     3121 ggcccgcgct gggtgctgcg cggggtggtc cgcggcgagg gggcggccag acccgaggcg
     3181 atgggcgaga tcgaacgcct cttcgccgac atcgtggtgg tccgcggcga gcagccctcg
     3241 ccccccggtg aactgctgca gatcaccgtt cccaagcagc tccaggagca gatggccgcc
     3301 gcccaggccc gtgcggccca tcaggcggcc cagagcggca acgccgggag atcccccaac
     3361 ggcagtgcgc cgggcggccc cgacggggcc tgagcccttc tccggccgcg ggggcggcgt
     3421 tcatcttaat gtggtgccat ggcacagacc aaggacagca acgccccccg gccgctcccc
     3481 gaggactggg accgcgccct ggcggtggtg gcccaccccg acgacctgga gttcggtgcc
     3541 tcctcggcga tcgcccgctg gaccggtcag ggcaaggacg tggtcgaact catggccacc
     3601 aggggcgagg cggggatcga cacgatcgcc ccgcacgagt gcgggcccct gcgcgtggcc
     3661 gagcagcgcg cctcggcggc cgaggtcggg gcgcgggacg tggagttcct ggacttcccc
     3721 gacgggacgc tggagtacgg cctgccgctc aggcgcgcac tggccgaggc gatccggcgc
     3781 caccgccccg aggtgctcgt ctccatcaac ttccgcgagg ccttcccggg cgggacctcg
     3841 ttcaaccatg ccgaccaccg ggtgctcggc cccgccctgc tggacgcggt ccgcgacgcc
     3901 gccaaccggt gggtgttcgc tgaccagctc gacggcgggc tccgcccctg ggccggtgtg
     3961 cgcttcgcgg ccttcggcgc ctcgccgagg cccacgcact acgtggagct ctccgaggcg
     4021 gacctggcgg cgggaatcgc ctccctggac cggcacgggg tctacctggc ccatctggag
     4081 gggttcgacc agaaggcgtt cctgtccacc gccgcccggg aggcgggcgg ccgggcgggg
     4141 acggcgctgg ccacggagtt cgaggtcttc gacacctgag agcccgctca gcccctggcc
     4201 ggacccgggt cctcggggtc ggcgacccgg cccaggaaga ggagcgtccc gccccgccgc
     4261 agcgcgaagg agaaggggcg gtccacggtg aagtcgacgg gccgggtcgg agccgccgcg
     4321 gccctcacca tgaccgcggc ggtggcggcg gccccctccg cgcccttctc gtccaccctc
     4381 atcacggcct ggtgcagcag ggcgtccact ttcagcggct ccccgctgat cccgtcgaaa
     4441 cgggcggcgt cggtggccag agtgcggacc ccgagccgtg ccaggggttc gagcaggccg
     4501 gtcccggtcc gcaccgcgaa gcgtggcagt gccaggcgta ccggggtgcg ccgcctggcg
     4561 cggtacaggg cttccagcgt gtccgcgtcg gggacggcgt cgcggccctg cgccagcagc
     4621 acgtccagcg ccagatcgtg ctcgcccctc agggacacca tgcgccaccc acgcgcgcgg
     4681 gcgaaggtca gatccccctc gcggtgcatg gcggggaccg tccggtcccc gcccggggcg
     4741 tggaagcgcc gggcgcgcgt ggcccgcacc tcgaaggggc acgcccacac caccttcgcc
     4801 cacagggcgt tggccagcag catgcgcacg tccgggccga cgctgccggg cgggagcagt
     4861 tcggggacga gcccgcgggt ggcctcggcg gccttggcgt tgatcctgcg gcgcacgccc
     4921 tcggggtcgc cgcgcacgtc ggctccgcgc acctcggcgg cgggtcgtgc acgcaccagc
     4981 tcggtgaagg ccgggcgcac cgccaggccg tcggggatgt agaggccgtt gaacgcggcc
     5041 agttccggcc cctcctgcgc tccggccgcc ccgtccagcg aggtgagcag ggcgtgcggg
     5101 tccgcgccca gcagtgactc cagttcgtcg cgggtgcctc cggaggagcc cgcggcgagc
     5161 aggcagagca cggtgcccac cgagtagggc gaccacacgt gggaggcgcg gggccgggcc
     5221 agcgcccggt ccagggcggc ggcgaactcc aggtggtcgc ggcggacggg ggtgtgcacg
     5281 ggacggcctc ctcgggtgtc gccgacagac tacggacggc cggtggtgtt cgtgacaccg
     5341 gacacacggc aagaggtatc gaactagcgc gaaacagcac gcgccgggcg ggtcgcggag
     5401 tgcggagccg gtgcgctttc cgtgcccttg gcggcgtgtc cactagtctt ggcggggacg
     5461 ggaccgggcc cccgaggcgg ggacggccgg acacgcacga gcaccgacca cggaccggga
     5521 gcgggatgac tgagcagcgg cgggccgccg aggaggccgc ccgggcggcg ggtgccgacg
     5581 acggcgggcc caaggtcacc gaggacacgg tcgaggcgct cgtgcgctcc cagttggcca
     5641 aggtactggg cggcaagcgc ggtatggtcg aggcggccgt gcccaccctg gccttcaccc
     5701 tctcctacat cgtcctgtcc aggatcgacg gggccctcac cctcttcggc ggcacctact
     5761 ccgacctgcg ggtggcgatc accgcgggtg tggtggcggc cctggtcctg ggggcggtcc
     5821 gcctcgtcca gcgctccacg gtgcagtacg tcgtcaccag cctgttcggg atcggtatcg
     5881 ccgcggtgtt cgccatgcgc agcggcgagg ccgccgacgc cttcctgccc ggcatcatct
     5941 acaacgccgt ctacgccgtc gtgctgaccc tgtccatcct ggtgcgctgg cccgccatcg
     6001 gcctcatgat cggcccgttc atcggcgaca aggaggacct cacctcctgg cgggccgatc
     6061 cggccgtggt ctcactggcc gccaagctca cctggttgct cgtcctgccc tgcgtgatcc
     6121 gggtgctcgt gcagtacccc ctgtggttca tggaccacta cgacatcgcc gacaccttcg
     6181 ccctgctcgg gctggccaag atcggtatgg gctggccgct ccaggtcgcc gggctcgccg
     6241 ccatggtgtg ggtgctcgcg cgcgggcgca cgcccctgcg ccagggaccc gacggggagg
     6301 ccggacgagg cggcgggggc ggccggggct gaccccgccc gggtgcctca gacgtccccg
     6361 tccgagccgt ccgccgggcc gagcaggccc tccaacgtct ccagggcacc gggttcagcg
     6421 aggaacacca cggtgtcgcc caccgccagg gtccgctccg acccgggcgc gcgcacgccc
     6481 ccggaaccga ccacggccac tagggccacc ccctcgggca gtcgggaggt gagcgcgctc
     6541 tcggggccgc cgacgaacgc gctctcggcg tgcagcaccg attcggcgat ctccgcaccg
     6601 ggcagcggcg gcgtctcctc ctcggcgaac ccgtcctcgc ccgcgtcctc gaccaggtcg
     6661 gcgatgagcc ggggtgggga gaccgccagg tccacccccc aggagtcgtt gaacagccac
     6721 tcgttgtcgg gctcgttgat ccgggcgatg acccggtcca ccccgaactc ggtcttggcc
     6781 agcagcgaca ccaccaggtt gaccttgtcg tcgctgctgg cggcgatcac cacgtccgcc
     6841 tcgcccaggc gggcctcctc caggctggcc agttcgcagg cgtcggcgag cagccactcc
     6901 acctgcgtca ggtcgtcgac gtcgatcgcc cgcgtgtcgc ggtcgatcag caggacgtcg
     6961 tgcccgctcg cggcgagttc ggcggcgatg gagcggccca cgcttcccgc tcccgcgatg
     7021 gcgatccgca tgtcagtgtc ccgtctcgtc gtcggagcgc agcgcgtcca ggtcccggcc
     7081 gcgcgcgacc acgtgcagga tgtcgcccgc ctccaggggc aggtcggagc gggcgagtag
     7141 gatgccgccg ccccgggcca cgtacaccac ccgtaccggc gtgcgcgact ccaggtccga
     7201 cacgcgccgt ccggcccaag tccgggggag cgtgacctcg ttcatcgcca gggtgccgga
     7261 ggcgtcgtgc cactccggcc ccgcggtgag ccgctggtcg ccggggacca tgcgccgcag
     7321 gatggtgtcg gcagtccagc gcaccgtgcc cacggtcggg atgcccagcc gctggtagac
     7381 ctcggcccgt cgggggtcgt agatgcgggc caccacgtgc tcgacgccgt aggtctcgcg
     7441 cgccacccgg gcggagatga tgttggagtt gtcgccgttg ctgacggcgg cgaaggcgga
     7501 ggcgtgctcg atgcccgcgg cgagcaggac ctcccggtcg tggcccacgc cgcggacggc
     7561 gtgcttggtc accgcgccgc gcaggcgccg gaacgcctcg gggtcctggt cgatgaccgc
     7621 gacggtgtga cccaggtcca ccagggtgtg cgccagggtg gagcccacgc gcccgcaccc
     7681 catgatcacg atgtgcacca tcactccagg atcgccgttt tcgactgcgg cgccgcgccg
     7741 ccgctccacg gtcacaccat ggcacacatc ctcccgacac gcgcggcgac cccggagccc
     7801 cgtgtgcggg ggcgtcccgg gcggctccgc acgtccacta gattggatcc ggttggtggc
     7861 tgtgcacgca ggtcacccgc gaacagcacc cggccgatct ctcttgagga cccttccatg
     7921 gcgacccgtg tgggcgacga gttcgaactg accgtgaacg acgccgcgca cggcggctgg
     7981 tgtgtggggc gccaccacga gcaggtggtc ttcgtccgcc acgccctgcc cggcgagcgt
     8041 gtccgggtgc gtgtcaccga gcgcacgtcg cgcttcctgc gcggcgaggc ggttgaggta
     8101 ctggaggcct ccccggaccg ggtcgaggcg ccctgcccct tcgcgggtcc gggccgctgc
     8161 ggcgggtgtg actggcagca cgcctcactg gcggcccagc gcgtgatcaa gggccgggtg
     8221 gtcgccgacc aactgcgccg tatcgccggg accgaccgcg aggtcacggt cgaggagctg
     8281 cccggcagcc ccgacggcct gggctggcgc acccgggtgc gcttcaccgt cgacgcccac
     8341 ggccgtgccg ggctgcgccg ccaccgctcc cacgacgtcg aacccgtgga ccggtgcctg
     8401 atcgcccacc ccggagtgga ggagctcggg atcaccgacg tcacctggga gggcgtgcgg
     8461 gacgtggagg cggtcgcctc cgcgagctgc gccgaccgcg ccgtcgtggt gaccccgtcc
     8521 ggttccaagc tgggccccct gcccgacctc aaggcctcca gcgccgtcct gcgccggttc
     8581 aagggcggcc gggtccagca ggtgcgcggg cgccgcgggg tccgcgagac ggtcgccgga
     8641 cgggagttcc gggtcggcgc gggcggcttc tggcaggtgc acccggcggc gggcgaggtc
     8701 ctcaccggcg cggtcatgga cgccttggcc cccagggaag gggagaccgc gatcgacctg
     8761 ttctgcggcg cgggactgtt caccgccccg ctcgccgagg cagtcggccc gcaggggcgg
     8821 gcgatggggg tggagggcgc agtcgaggcc gtgcgcgacg cccgctacaa cctcaaggac
     8881 ctggagcagg tgcggatcga gcacggggac gtggccgcgc agttgcggga gtgggccgac
     8941 gtgcgcgccg acgtggtcgt cctggacccg ccgcgggcgg gcgcgggcgc cgagccggtc
     9001 cgcctggtcg cgggcatgcg gccccgcgcg gtcgcctacg tctcctgcga cccggccacg
     9061 ctcgcccgcg acctggcctc cttcgagcgc gaggggtacc ggctcacggc gctgcgcgcc
     9121 ttcgacgcct tccccatgac ccaccacgtg gagtgcctcg ctgtgctgga gccggtgcgc
     9181 ccggcccgcc gccaccgcga gcgtgcctag gaggccgcgc ccggggctcc gccgacccgg
     9241 cgtcggcgga gccccgggca ctcatctttt ccccgagaac ctacggccaa ccccatctgt
     9301 ggtaaagaat ttcatccgtc gttctccgcc agtgtctgat aagggtccgc ttccgttccg
     9361 cggtgccctg tgccgcgagt tctaagatcc atcactgtga accgggtgaa ggatttttct
     9421 ggagtttggc ggcagggttg gggtggatgt gtggtcgtcg gaaacttctc tatagaattt
     9481 gattcctctg cggcatccgt ccgggggtgg ggttccttct gttctctagt gaaatctcca
     9541 cggtaattcg tcctacgttt tcctggccca ggggcccgtt tccgcctgcc ccgataagaa
     9601 agtgctgtcc acgagggggc cgggagtccg gctcaccttc cactgtcgcc acggggttct
     9661 cagaaatttt tgaagccaca gttcgatgac aggggcccag tggtgtaaaa acgccacacc
     9721 agaaacctcc cgtggctccg acctgctctt ttcgttgttc cgtgtgatgg ttggtggttt
     9781 tcgctcatcc ccgcgcggcg gcgtgatctt ggagaatccc ctggcagggt gcttgaatgt
     9841 tcagtgcgag gttcaccgga gaggtggtct taactctcga gtaagggttc cgggtggcga
     9901 tcaatggccg taaaaactat gcgtaaaggc atggacacgg atatgtgggc tgtgtcaata
     9961 tctggatgtc gctgaacgga acggctttga gggagttcgt atgatcaggg ggtatggcgt
    10021 tttctgtgac gccgaccgct acttctacga cacgccccac cgcctctggt cgggctccgg
    10081 cgcggacgac gggcgcggcc cggtcttcga ggcggcccgg cgcccggtgc ccgaggggtg
    10141 gcagagccac cgggccggcg actggctggc gctgcgcccc gtcgagcccc gcctgccgga
    10201 ccagggatgg aagatccacg tctcggcctg cctggacaac gccgagtcgg tcctgggccg
    10261 ggtctgggac tactgcgtgg cgcggggcgt ctccttcaag ttcgtcccca cccggtacct
    10321 gctgcacaac cggaatgcca agtacgccga ccgcgggggc agcgggaagt tcatcaccgt
    10381 ctacccggcc gacgacggcg agtgcgcatc ggtcgccgcg gggctggacg cactcgtggg
    10441 cggtgagccc ggaccgtacg tcctcagcga cgtgcgctgg aacgcgggac cggtccacct
    10501 gcgctacggg agcttcacca ggaggcactg ctacgacaag cacggtgatg cggtgcccgc
    10561 gctggagaac gccgaaggcg tgctcgtgcc cgaccaccgc ggtccggtct tccgcctgcc
    10621 ggagtgggtg cctgtccccg acttcctccg ccctcacctg gaggcgcgtg gggccgtcga
    10681 cgtcaccggt ctgccctacg acatcgaacg ggccctgcac ttctccaacg gcggcggtgt
    10741 ctacgcgggg cgcgaccggc gcaccggcga gtcggtggtg ctcaaggagg cccggccgca
    10801 cgctggcctg gccgccgacg gtgccgacgc ggtacgccgc ctggaacagg agcgcaccgc
    10861 cctggagcgc ctcgccggac tgccctgcac ccccgaggtc aaggacgcct tcaccctcgg
    10921 cgaccaccac ttcctggtca tggagtacat cgagggcaag ccgctgaact ccttcttcgc
    10981 gcgccgccac cccctggtcg aggccgaccc cgcgccggac gcgctgaggg actacggccg
    11041 gtgggcgatg cgcgtgcacg gcctggtgtc ggaggcggtg cgggccgtgc acgaacgcgg
    11101 catcgtcttc aacgacctgc acctgttcaa catcatggtc gccgaggacg agtcctcggt
    11161 ggtgctgctc gacttcgagg cggcccggga cgcaggccag gacagccgcc agacggtcgc
    11221 caacccgggg ttcgtcgccc cgcgtggtcg ccgggggttc gatgtggacc tgtacgcgct
    11281 ggcctgcctg cgcatcgccc tcctcctgcc cctgaccagc gtgctggcca tggaccggag
    11341 caaggtccgg cacctggcgg aggaggccgc gcgtgtcttc cccgaggccc gggagttcct
    11401 ggaggccggc gtcacggaga tcctgcgcga cccggacgac ggtacgggtg cgcccccggc
    11461 cgctaccggc gtgcacggtc cctacctgcc ggccgagccg ggggactggc cgcgcggccg
    11521 ggactcgatg gtccgtgcca tcctcgcctc ggcctcaccc gaccgggagg accgctgctt
    11581 ccccggtgac atcgcccagt tcacgacagt ggggggcggg ctctccttcg gctacggcac
    11641 cgccggggtg ctctacgccc tcgccgagag cggcgccccg cgatgccctg aagccgagga
    11701 atggctgctg cggcacagca aggaacccga ctcgggtttc ccgccgggtt tcttcgacgg
    11761 cctctccggc ctgtcctggg tcctgcgccg cctcggctac gggcaaccct ccctggcact
    11821 ggccgaactg gtcctcgctc agccgtggga ggggctcgga cccggattgc acagcgggac
    11881 ggccgggatc ggtctggcgc tggactccct ggccgctgac accggcgatc cggaagcggc
    11941 ggcgggagcg ctccgctgcg cggaactggc cgtacacggg ttcttgggcg ctccgcccga
    12001 acgccgccgc gccggtctgc tctacggagg cgcgggtgtg gccctgctct gtttgcgcct
    12061 gtacgagagg accggtgaca ccgggctgct cgactcggcc gaacgggcgc tccgggccga
    12121 tctcgaccgc tgtgtcacca gcgccttcgg cacgctccag gtggacgagg ggtggcgcac
    12181 catgccctac ctcggcgcgg gcagcgtggg ggtggggatc gtgctcgacg actatctgga
    12241 gcaccgtgca gacgaggagt tcgagcgggc ccggccggag atcgccgggg ccgcgcggtc
    12301 cggtttctac gcccagcccg ggctcttccg gggcctggcg ggcatggtgc tgtacctgag
    12361 tcggacgacc gccccgggca ccggggccgg ggacgtgcac cgccaggtcg acgccctgtc
    12421 gcgctacgcc atgcgctacc ggggccacct ggccttcccg ggagagcaac tgatgcggct
    12481 ctccatggac ctttccacgg gcacggcggg atgcctgctc gcgctcaccg cggcgcgcgg
    12541 cgcacccgcc caactgccct tcctccctcc gctgaggcgg acccagagcc gggccactgc
    12601 catggcccgg aacaaagaag agaagaagaa cgagtaaccg acgagaggat atcagtcatg
    12661 accctgttcg acctgcagtc cctggagacc gccaaggacg aggcccacgg cgaggccacg
    12721 gccaccagca ccgccagcct cctgctgtgc ggcgacagca gcctgagcgt caccacctgc
    12781 taggggcgcg ccgcggatga gcgcggcgcg accgggccgt ggggctggga atccggcccc
    12841 acggcatcgg gtccggtgaa cggacctcct cctccggccc ggcggtgccc ctgggcgccg
    12901 ccgggctccg ccacgagcca cgcaggaagg cggcccggat ggtgcccacc cgcccgcgcg
    12961 acggtactgc cgacggcggc gccgcccggt ccgcggacgc cctgctcacc cgcatggtcc
    13021 gggccagtgc cgggcggacc gcggggatcc tgctgtgcgc ggccgccgcg gcggcggcct
    13081 cactcgccct gcccgccctg ctcggcctca ccctcgacct gctcctggag gggcaccccg
    13141 acgccggacg ggctctggcc gcggtcgtgg tcctgactgc cgccgaggtc gggctggacg
    13201 cggccgtcgc cctgctgtcg ggcacggtcg gcgcgcgctc caccgcctgg ctgcggctgc
    13261 gggcggtccg gcggctgctg gccgccgcgc cccgggacgt gagccggttc tctaacggag
    13321 acgtcgcgac gcggctctcg gcgcacgcca ccgaggccgg ggccgccccg gccggggcgg
    13381 cgcagatcgt cgccgcggtg ctcgccccgg tcggagccct ggtggcgctg ttcgtgatcg
    13441 acccgtggac cgggctcgcc ttcgtcctag ggctgcccgt cctgggactg cttctgcgct
    13501 ccttcgcacg ccactcctcc gacaccgtct cccgctacca gcgggtgcag tccctgatcg
    13561 cgacccggct gacggacgct ctgggcgggg cacgcgccat cgccgcggcc gggacactgg
    13621 aggacgagcg cgcccgcgtc ctgagccccc tggccgatct cggcgtcgag ggacggcgca
    13681 tgtggtcggt acacggttcg gcgatggcgc gcagcggagt gctcatgccc ctgctcatca
    13741 ccgccgtgct cgccgtcggc ggcgtcggtc tggcgcacgg gaggatcagt gtcggcgatc
    13801 tgctggcggt gtcgcgctac gccgcgctgg ccgcggggct ggggtcggtg gccggccccc
    13861 tcgcagcgct ggtccggggc cggacggcgg cccgccgggt gggcgcgctc ctggcggttc
    13921 ccccgctggc ccacgggcgg gcacagcttc ccccggcggg ccccggaacg ctggaactgc
    13981 gcggcgtcgg ggtaaacacc gacggcgtgt gggtgcttcg gggggtcgac ctgcgggtgc
    14041 ccggcggccg gacggtggcc gtcgtggggc gctccggctc gggcaagtcg acgctgggag
    14101 ccgtcgccgg acggcttctc gcccccgacg agggcgaggt ctgcctggac ggcgtgcccc
    14161 tcgacaccgt ggccgccgac gtgctccgcc gggaggtcgt gtacgcgttc gagcgccccg
    14221 agctccaggg cgccaccatc gcggacgcca tcgccgctgg ggcccggacc gctccggacg
    14281 aaggagtgcg gtcggccgca cgggcggccg gggccgacgg cttcgtgcgg gcgcttcccc
    14341 tgggatacgc cacgccgctg gaggaggcgc cgctctccgg cggggagctg caaaggctgg
    14401 ggctggcgcg ggcgttcgcc cacgcgggac gcctgatgat cctggacgac gccacctcca
    14461 gcctcgacac ggcgaccgaa cgtcaggtgg accgggcgct ggcgcacgag gtccgccccg
    14521 gcacccgtct ggtgatcgcc caccggctct ccaccgcggc ccgcgcggac ctggtggtgt
    14581 ggctggagga cggccgtgtc cgggccgttc gcacacacgc cgaactgtgg cgggaccccg
    14641 actaccgcgc ggccttcggc cgcaccgacg cctcaggcca ccgggaggag cggtgaggcc
    14701 cgggacggtg gtggacgagg cgaccggccg gcccccggca cggcccgggc ggggccgtcc
    14761 gagtccgcgg ccggaccacc gccggggttc gctgcgcgct ctggtgccgc acgcccgccc
    14821 cttcctgtgg cgccacaggc gcgtgctgct gaggctgggc gcctggtcgc tggtggagtc
    14881 cgttcagacc ttcctggtcg ggatctgctt ggcacgcgcc ctggaccagg gcttcctggc
    14941 ggggcggacc gccacgggcc tggcgtggct cgccgtcgcc gcgggctcga tcctcctggc
    15001 gggccccgtg ctgcgcggcg tgttcggcca gctctccgcc ttggtggagc cgctgcggga
    15061 cgggctcgta cggcgtgcgg tcggacaggc cctgcgccgg gccgtggccg atccggcgcg
    15121 tgcggcgagg gtggagcggg ccgcggtctc gcggctcacc cagcagacgg agatcgcccg
    15181 ggacagcttc gcagggctgg tcctgacggt gcggtccttc ctgttcaccg cggcgggggc
    15241 gctcgtgggg atgctcgccc tggcccccga actgctgctg gtcgtggtac cgcccatgct
    15301 ggtaggcctg gcgctcttcc tttgcacgct cgcgcccatg gcggcggcgc agcgccggtt
    15361 cctggacgcc gacgaggcgt tcaccgaacg tgcgggagcc ctgcgcggcc agttgcgtga
    15421 cctggtggcc tgcggtgcca cggacgccgc ggcccagcgg gccgggcccc tggtcgacga
    15481 cgccgccgcg tcgacccggt ccctggcccg ctgggcggcc gtgaggacgc tggcgctcgg
    15541 tacggcgggg cagctccccg tcgtcctgct gctcgtggcc acgccgtggc tgctcgacca
    15601 gggcgtcacg actggggccc tcatgggtgc cctggcctat ctcgtgcagt ccctgatgcc
    15661 ggcgctccag acgatgatga ccgcggtggg tgccgctggc agtcggctcg tggtggtcct
    15721 cgaccggttt gtgtccgcgg aagcggacgg tgccgacggg ggaggcgtcc cccacgagga
    15781 ggccgacggc cccgtgttgg ccacccctcc cgctccggag ggggtcccgg cggtgtggtg
    15841 ccgcggggtg cgggtgtcct acggggcggg gacgcgcccc ctggtggagg ggctcgacct
    15901 ctcggtggag gcgggggagc gcatcgcggt cgtcggaccg agcgggatcg gcaagtccac
    15961 gctggcgcac gtgctgtccg ggctgcaccc ccccgacgaa ggcgacgtgc gcctggcggg
    16021 ccgcccggtc gccgggcgct cccctcgcga actggcacgg gaacgggtcc tccttcccca
    16081 gcggggctac gtcttcgccg gatcggtccg ggagaacctc gcccagttgg agcccggggc
    16141 cggggacgac cgcctcgccg gggcggtggc ggcactgcgc ctcgggccgc tggtggaccg
    16201 cctcggcggc ctggcggctg aggtggaccc aggggcgctc tccgccgggg agcggcaggc
    16261 gctctgtctg ggccgggcct acgtgtcccg ggcgccactg ctcatcctgg acgaatccac
    16321 ctgccacatg gacccggtcg ccgaggcgca cgcggaggag gcactggcgg cacggcccgg
    16381 tacgacgctg atcgtcatcg cgcaccggct gtcgtcggcg ctgcgggcag atcggatcct
    16441 cgtcttggac ggagcgggta cggcgctggg cacgcacggg gccctgctcc gcagctcacc
    16501 gctctaccgg gacctggcgg ggcactggaa tgcgtctgtc tgagcacggc cgagggcgcc
    16561 caccgtgcgc tcggccgccc gtcagccgag ctgggaatag gaaggatgcc ccgcgatgcc
    16621 cgggctcgcg gcgagcgcgc tcccggatcg ggcgccctgt ggtggcggcg tcgcgggtgg
    16681 gtgtcccggg ggcggcgtgt cagccccggc ccggggcgcg ggcggtgccc gtgtgcccgc
    16741 ctccgtgcgg tgattgcggc gcgtccgccc cggccgccgt cccgagggag tccgcaggac
    16801 ggccagaccc agcgcgagga cggccatccc cgtccaggcg gcgggggaga ggcgctcgcc
    16861 gaccacggac acccccagga gcgcggccac ggcgggctcg gccaggctca gtgtggtggc
    16921 cgtcgccgcg ggggtgtgcc gcagcccgac tccgaagagc gtgtaggcca ggaagacggt
    16981 gaagagcgcc aggtagaggg cgaccgccgc gccgcgcccc gtggccagcc acaccggatc
    17041 cagggccagg accacggggg ccgtgaccag gcccccgccg gcgaacagta cgcccatgac
    17101 cgcgccggag gggtggccgc gccggatctg tgctgcggag accaccgcgt acagggcgta
    17161 ggaggcaccc gcggcgaggg cgaggagcac gccggaggtg tccacggtcc gtgcaccgtc
    17221 cccgccctct gcgccgagga cgaggagtgt gcatccggcg accgcggcga gggtggccgc
    17281 gctccaccgg cacccggggc gcacgccttc ggacagccag gcgaggaggc cggcgaacac
    17341 gggtgccgac cccagggtga tcacggtggc caccgccacc cccgcctgcg cgaccgccgg
    17401 atagaaggcc agcgggtatc cggcgaccgc cagggctccc agggcgagcg ctccgcgggt
    17461 gcggcggtcg gcaccgtgga gcagggccgg gtagccgcgc ccggtgaaca ggagcagcag
    17521 gccgcccacg gccagcccgg cggagccgat ggcggcgggg tgggccccgg cgggggcgaa
    17581 ggaggccgct gttccggtag tgccccacag cagggcggcg cccaggacgg gcagggggcc
    17641 ccgggcgagg ccgcgccggg gcgcgggggc ggtgggcgtc gtcgacactg tcgcgtctct
    17701 cctctccgtc atcgggggtg gtgggccggt gacgggcgca cgcggtgcca gtggccactc
    17761 acctgcgtga ttctaggaca taaaggggtg aatcgggctt cgctggacgc ggtccgcggg
    17821 ccgcggtccg ggtgctggcg tgcggcagcg gtgcgcgaag ataagctcct acgtctgagg
    17881 atcttcatcg ggccccggca gggggccggg accagctcgc catcgcccgg gcggcggagg
    17941 acctgggctt ggacgccctg ttccgctggg aacaaggaac ttcctgagtg ggggttgggt
    18001 agtcgcttgc tccgtgcgtc cgttccggcc acgacccgca catgggcggc cgcgccgccg
    18061 gaccgcccgg tcccaccgac gcatgggtcg ccctcgcggc actggcgcgg gagacctccc
    18121 ggacccgcct ggacacactc atgagtgccg cgaccttccg cctgcccggc cccctcgcca
    18181 tcaccgtcgc ccaggtcgac cggatgagcg gcgggcgcgt ggggttcgga ttcggtacgg
    18241 gctggtacga ggccgagcac gccgggtacg gggtcgcctg ccccagtctg cgcgagcgct
    18301 tcggccgcta cgaggagcag gtggagatcg tcaccgggct ctgggagaca ccggagggcg
    18361 ggtcgttccg ctacgagggc gggtactacc gtctggagga ggggcccgcg ctgccccaac
    18421 cggcgcaggc gccgcgcccg ccggtgctga tcggcggcgg gggaaaaggc gcgctccccg
    18481 tctggccgcg cggttcgccg acgagtacac cgtgccgttc gcctcgctgg aggagagcac
    18541 ggccgcgttc gagcgcaccc gtacggcggt gcgcgccgcc ggaagggagg cacccgtggt
    18601 ctactcggcg gcacaggtgc tgtgcgcggg cggaaacggg gcggaggtct cggccagggc
    18661 cgaccggatc taccttcagg ctctggacat ggccgacctc gaccacctgg aactggtggc
    18721 cgcgaggatc gtgccacagc tcggttgagg gaggcgttcg gaggggggcg gcgcgggagg
    18781 ccgggaggcc acccgataac ttgatatcga gatatgagtt ggataccttg acatcaagat
    18841 aacagcgggg ttccccccgg tccgctcagg gttcgggtgt gtggacgcgc gaccgcttgc
    18901 ccacgcccgg gccccggcgg acgccccgcg gggctgacgg tcggcggcgc gtggtgtcgc
    18961 cgcgggtcat cgtcggccct gcggagcgac cggaggcggt ggagggcggc ccgtggccct
    19021 ccgggccccg gtcggggccg tcccggcagg ccctgcacca ggcctacggc cgagaggccg
    19081 ggaacacagt ggcgagatac aggaggcaga caccgtgtcc gcgaacagct tcggcgcccg
    19141 tgacacgttg cgcgttggcg acgagtcgta cgagatcttc cggttggagt ccgttgaggg
    19201 cgccgaccgg cttccctaca gcctgaaggt gctgctggag aacctcctgc gcaccgagga
    19261 cggcgccaac gtcacggcgg accacatccg cgccctgggc cagtgggacc cgaaggccca
    19321 gcccaaccag gagatccagt tcacccccgc ccgggtgatc atgcaggact tcaccggcgt
    19381 cccctgcgtc gtcgacctcg ccaccatgcg cgaggccgta cgcgacatgg gcggcgaccc
    19441 cgacaagatc aacccgctgg ccccggccga gctggtcatc gaccactccg tcgtcgtcga
    19501 cctcttcggc cgccccgacg ccttcgagcg caacgtcgag atcgagtacg agcgcaacta
    19561 cgagcgctac aagttcctgc gctggggcca gaccgccttc gacgagttca aggtcgtccc
    19621 gcccggcacc ggcatcgtgc accaggccaa catcgagcac ctggcgcgcg tcaccatgag
    19681 ccgtggcggc caggcctacc ccgacacctg cgtcggcacc gactcgcaca ccaccatgca
    19741 gaacggcctg ggcatcctgg gctggggcgt gggcggcatc gaggccgagg ccgccatgct
    19801 cggccagccg atctccatgc tcatcccgcg cgtggtcggc ttcaagctct ccggtcagct
    19861 cgcgcccggc accaccgcca ccgacctggt gctcaccatc accgagatgc tccgcgagca
    19921 cggcgtggtc ggcaagttcg tcgagttcta cggcgagggc gtctcctccg tgccgctggc
    19981 caaccgcgcc accatcggca acatgagccc ggagttcggc tccaccgccg cgatcttccc
    20041 gatcgacgac gagaccatcc ggtacatgaa gctcaccggc cgctccgccg agcaggtcgc
    20101 cctgaccgag gcctacgcca aggccaacgg cttctggcac gacccgtccg cggagcccca
    20161 gtactccgag tacctggagc tggacctggg ccgggtcgtc ccgtccatcg ccggccccaa
    20221 gcgcccgcag gaccgcatcg ccctgtcgga ggccaagccg acctggcgcc acgacgtcca
    20281 gaactacgtc gccgacgacg aggcgggcga ggagtccttc ccggcctccg acgccccggc
    20341 ccagagcgcg gacggccgcc cgtcccgccc ggtcaaggtc accatggccg acggcaccga
    20401 gaccgagatc gaccacggcg ccgtcgtgat cgccgcgatc acctcctgca ccaacacctc
    20461 caacccctcg gtcatgctcg gcgccgccct gctggccaag aaggcggtgg agaagggcct
    20521 gtcccgcaag ccgtgggtca agacctccat ggcccccggg tccaaggtcg tcaccgacta
    20581 ctacgagcgc tccggcctga ccccgtacct ggacaagctg ggcttcaacc tggtcggcta
    20641 cggctgcacc acctgcatcg gcaactccgg cccgcttccg gaggagatct ccaaggccgt
    20701 ccaggacaac gacctcgcgg tcacctcggt cctgtccggc aaccgcaact tcgagggccg
    20761 gatcaacccg gacgtgaaga tgaactacct ggcctcgccg ccgctggtgg tcgcctacgc
    20821 cctggtcggg tccctcgacg tggacatcac caccgaaccc ctgggcgtcg gcaaggacgg
    20881 cacgccggtc cacctggccg acatctggcc ctccgccgag gagatccagg aggtcatgga
    20941 cgccgcgatc gcctccgaca tgtacgagag cgcctacgcc gacgtcttcg ccggcgacga
    21001 gcgctggcgc tcgctgccca cgcccaccgg caacaccttc gagtgggagg gcgggtccac
    21061 ctacgtccgc aagcccccct acttcgaggg catggccgcc accccggccc cggtcaccga
    21121 catcaccggg gcccgcgtcc tggccaaact gggcgactcg gtcaccaccg accacatctc
    21181 cccggccggt gccatcaagc cgggcacccc ggcggccgag tacctcaagg ccaacggcgt
    21241 cgagcgcagg gacttcaact cctacggctc ccgccgcggc aaccacgagg tgatgatccg
    21301 cggcacgttc gccaacatcc gcctgcgcaa ccagctcgcg ccgggcaccg agggcggcta
    21361 cacccgcgac ttcacccagt ccgacgcccc ggtctccttc atctacgacg ccgcgcagaa
    21421 ctacgccgcg caggagaccc cactggtcgt cctgggcgga aaggagtacg gttcgggctc
    21481 ctcgcgcgac tgggcggcca agggcacccg cctgctgggc gtgcgcgccg tcatcaccga
    21541 gtcctacgag cgcatccacc gctccaacct gatcggcatg ggcgtgctgc ccctacagtt
    21601 ccccgagggc cagtccgcgg actccctcgg cctgaccggt gaggagacct tctccattac
    21661 cggcgtgacc gagctgaacg agggccgtac cccgagcacg gtgaaggtgg ccaccgacac
    21721 cggcgtcgag ttcgacgccg tggtgcgcat cgacaccccc ggcgaggccg actactaccg
    21781 caacggcggc atcctgcagt acgtgctgcg ccagctcacc gcgaagtagt cgcccacagg
    21841 actccgcccg cgcccaccag gcgcgccgcg cggataccgc ggggccgcca ccgtccgacc
    21901 gacggtggcg gccccgtccc tcttggaccg aaaccggccc ccgggccttc cgggccccga
    21961 aaggcgaccg tgcgtggctg ggccaacccg ctgcacggca ccgacacccg gcaggtccag
    22021 tggcgggagt ccggcggaga ccggagcgtc cgcgtgcccc tgtggcggga gcgcgccgcg
    22081 gccgcgcgca agcgggcccg tcccaccgtg ccgaccgacg agcacgtcgg gcgcggtgtt
    22141 ccctactatg aggtgcccgc gcggaagagc gtgtgggcgg ccacggggta cggcactccc
    22201 gccggcggcc tcgtgcggcg gatccagagg ggcgaccacc gccgcgcgtc ggacacgcgc
    22261 tgacgggtga aggcacacga gcgagcgaag tgaggggcgg caggtctgtg aacgactccg
    22321 cgaacggccg ggagacgatc ggtggctacc gggtggtccg gccactgggc aggggcggct
    22381 tcggagaggt gttcctctgc caggcccccg acgggtcccc tgcggcggtc aagctgctgc
    22441 acgccacttt ctccggcgac gaggagacgc gccgccggtt caccgccgag gtggaccagg
    22501 cgcgcaaagt gagcgggttc tgcatcgcct cgatcctgga cgccgacccg gaggcggccc
    22561 agccgtggat cgccacggag ttcatcgacg gccctacgct gcacgccgcg gtggccaagg
    22621 acgggccgcg caccggt
//
