LOCUS       NZ_AZXF01000034        16565 bp    DNA     linear   CON 21-OCT-2024
DEFINITION  Nocardiopsis sp. CNT312 B042DRAFT_scaffold_28.29_C, whole genome
            shotgun sequence.
ACCESSION   NZ_AZXF01000034
VERSION     NZ_AZXF01000034.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nocardiopsis sp. CNT312
  ORGANISM  Nocardiopsis sp. CNT312
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsidaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 43290)
  AUTHORS   Jensen,P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R41043
            investigation_type                :: bacteria_archaea
            project_name                      :: Nocardiopsis sp. CNT312
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi14643
            Funding Program                   :: DOE-CSP-ICBG 2011
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000515115.1-RS_2024_10_21
            Annotation Date                   :: 10/21/2024 21:26:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,296
            CDSs (total)                      :: 4,234
            Genes (coding)                    :: 4,144
            CDSs (with protein)               :: 4,144
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 23 of 90
            Pseudo Genes (incomplete)         :: 74 of 90
            Pseudo Genes (internal stop)      :: 5 of 90
            Pseudo Genes (multiple problems)  :: 12 of 90
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:21:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 16565
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AZXF01000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..16565
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..16565
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..16565
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[5488:6565](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5489..6565)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(<1..228)
                     /locus_tag="B042_RS23380"
     CDS             complement(<1..228)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025304.5"
                     /locus_tag="B042_RS23380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_155988858.1"
                     /transl_table=11
                     /translation="MPERRMLTLAEREEIALANARGEGVRAIARLVGRDQSVISRELAR
                     NTSKRGYRATTAHQRAKARRARPQQRLMDTD"
     misc_feature    complement(245..261)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     misc_feature    245..261
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            complement(<336..611)
                     /locus_tag="B042_RS27095"
                     /pseudo=""
     CDS             complement(<336..611)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="B042_RS27095"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF5753 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGAAFPPRSPRSIEDLLKARLDRQKILRRDRPPLALFVVDEGALR
                     RTAGGKSVMREQYKALIEAAEWPFVQIQVLPFDRGAHAAMEGSLVLL"
     gene            complement(577..1050)
                     /locus_tag="B042_RS27100"
     CDS             complement(577..1050)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="B042_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /protein_id="WP_081748810.1"
                     /transl_table=11
                     /translation="MWPDSELQVRQGASNCGPLWLAGVMPSRTSLPESAAIAQFGNELR
                     RLRNLSDMSQKDLGLATGTSKQQVGAIERGDRRHSKQFAELADKAPEAHNALLNLWPGA
                     KQAQPWWLEKFVELEAKAQVINEFQSQAVPGLLQTEGLRESRDGGGLPSPITS"
     misc_feature    complement(1030..1032)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1286..1732
                     /locus_tag="B042_RS0115345"
     CDS             1286..1732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020379951.1"
                     /locus_tag="B042_RS0115345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_028649056.1"
                     /transl_table=11
                     /translation="MQCTSPPSALPRRLRGTPTTSGLLLGPDLSHIAIARRWAAQATRT
                     RPGLAEPLALAVSELTTNAMRHTASGLPGGTVRVEIDRTGHLELRVTDDGPRPDTATTP
                     PAIPALDPFRVGGNGLRLVEAVCAYWDWTRNPDGGTAVRALFPR"
     gene            1852..2499
                     /locus_tag="B042_RS24425"
     CDS             1852..2499
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS24425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_051415730.1"
                     /transl_table=11
                     /translation="MTVLLCGHCGSPRHGGAPAYRCACIPAQVWQAPDLARAVRALDLS
                     KVIRYLRRHPATQHHSQAALASMCGLSQTTLSRLEGGRGATRIDRAVTALAGLGAPQVP
                     GEVNNPYPDEDPPPPPGPNGGPPGEVALTVGADGPRRLLDHGTAWGVTNTPRGATDWFA
                     LPTPANHALPRSPHPKGNTGPAVPDGAAPPGTGPTGRGGPWAGGGQGLGWSG"
     misc_feature    1857..1874
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
     gene            2496..3158
                     /gene="thiE"
                     /locus_tag="B042_RS0115355"
     CDS             2496..3158
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017600001.1"
                     /locus_tag="B042_RS0115355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_028649057.1"
                     /transl_table=11
                     /translation="MRTSHGDSLRKHLDASLLYLCTGARREQGDLAEFADAALAGGVDI
                     IQLRDKGLEAREELVALEVLRDACERHGALLAVNDRADIARAVRADVLHLGQRDLPVPM
                     ARDIVGSDPIIGRSNNDIEAAAASASEPGSDYFCVGPVWATPTKPGRAAAGLELVERAA
                     ALDTGRPWFAIGGIDLSTIDRVLDAGARRVVVVRAITEAEDPRAAAAALRARLTARD"
     gene            complement(3165..4058)
                     /locus_tag="B042_RS0115360"
     CDS             complement(3165..4058)
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154128.1"
                     /locus_tag="B042_RS0115360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_028649058.1"
                     /transl_table=11
                     /translation="MGDDHMTNHTIGVTGATGAVGGRVAARIARLGLAQRLIVRDINRA
                     PEFPGSSASMAAYEDTRSFERACRGVDTLFLVSATESEKRVETHVGAVDAAVAAGVSRI
                     VYLSFLNAGPASTFTFARTHFFTEAHIRMSGAEFTFLRPGLYLDLLPTWTDGRGVVRGP
                     AGDGRVAWVSRDDVADVATAVLTDPAVTAVSGGAAYDITGPEALTLGATVDKLSSLTGR
                     TIRYVPETWEEALESRRWTGAPEWAVEGWASSYAAIATGELDVVAPTVPKLTGHPAQSI
                     EGFLRRHPSALSHVAV"
     gene            complement(4114..5370)
                     /locus_tag="B042_RS23390"
     CDS             complement(4114..5370)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590394.1"
                     /locus_tag="B042_RS23390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_036555234.1"
                     /transl_table=11
                     /translation="MSTHTASRGPTETGERSLAPDLARGSMLAFIAIANATWYLWALPM
                     SGASAHPAPEGPADGIAQFVTTAAIDMRSYPMFAFLFGYGMVQLTRRQEAAGVSPREAD
                     AVLRRRNLWLLVFGLVHALLLWVGDILGAYGLAGLVLAWLFLRRRNATLLVWAGLLTAL
                     MAALAALSLLSLAFVPPEEMAGQSFGQEDMAASISDPSYLASVVERLTYWPVVTLGQGL
                     LGMAVPAAILLGFWAARRRVLEEPGRNVGLLRAVAVGGLATGWIGGLPLALAQTGFWDL
                     SEGQGLLLSLPHMVTGLAGGLGYVAAIALIAHRIERGRGTGPVAGALAATGKRSMSAYL
                     AQSVLCAPVLAAWGLGLGAHLTSWSMLLFAVGVWLVTVVAAALLERAGRRGPAEVLLRR
                     LAYRGAGEAKSAPPVDRNR"
     gene            complement(5489..6565)
                     /locus_tag="B042_RS0115370"
     CDS             complement(5489..6565)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610776.1"
                     /locus_tag="B042_RS0115370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_028649059.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.4e-46, bitscore:
                     148.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPFASPSPVSVVRSAVDGELVSFCASHRTRLLEIGEELAPAMDA
                     LEAMLSGGKRLRPTFCYWGWRGGGGADGDARVVRAAASLEFLQACALMHDDVIDRSDTR
                     RGLPATHRRLAALHTEHGWSGDADSFGEGAAILIGDLCLAWSDEMYQASGFAPEVLQGG
                     RAPFDAMRTEVMAGQYLDTLEQVRGTESREAALRVMRYKAAKYTIERPLHLGAALAGRL
                     DALGGVYTGYGMPLGVAFQLRDDVLGVFGDPGTTGKPAGDDLREGKRTLVVAETLERAD
                     SGAADRFRSLLGTPDLSEASVEWMCALIEDSGALKACERLIEEYSEQALSALESPELDG
                     SAREPLRWLVDAATSRTH"
     gene            6813..7676
                     /gene="metF"
                     /locus_tag="B042_RS0115375"
     CDS             6813..7676
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017546555.1"
                     /locus_tag="B042_RS0115375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_028649060.1"
                     /transl_table=11
                     /translation="MFSFEFFPPRGPKSQARLWRAIREIEALGPSFVSVTYGAGGGTRD
                     LTVETTERIAADTTLLPVAHMTLVDHSVAELRHLIGRFSAAGVSNMLAVRGDPPGDPGG
                     PWVRHPQGLTYAEELVRLLKDSGDFSVGVAAFPHKHPRSDDVETDTDHFVRKCEAGADY
                     AITQMFFDPEEYLRLRDRVAARGCGVPIIPEVFPVVRRATIERSEQLSGAPFPRDLAER
                     FERFGDDAEAVRAFGIEHAQRMCERLLAEGAPGIHFITFNQSTATREIYREVAGHRAGP
                     AEAARP"
     gene            complement(7594..8202)
                     /locus_tag="B042_RS25145"
     CDS             complement(7594..8202)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017599995.1"
                     /locus_tag="B042_RS25145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_197024331.1"
                     /transl_table=11
                     /translation="MAADTELRELAPPAFAHAVPVLLGVYDRAMRPPEDQLPGRAAVMS
                     GHARYPGFRSVVAVRGERPVGFAYGFHGGRGQWWHDVVTEAMRARGRARLAHRYLSDTL
                     EIAEVHVDPDEQNRGVGRSLLHALCSGRPERTAVLSTRTGPTAARHLYSSCGFTEILED
                     FSFPGSPAQPFSVMAARLPLGPPGGRRPRGRSPWWRWTG"
     misc_feature    8285..8300
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.07"
                     /tool="antismash"
     misc_feature    8286..8299
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 20.05"
                     /tool="antismash"
     gene            complement(8436..8930)
                     /locus_tag="B042_RS0115385"
     CDS             complement(8436..8930)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="B042_RS0115385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="WP_028649061.1"
                     /transl_table=11
                     /translation="MPSEYAKSLGARLRAIRTQQGLSLHGVEEKSHGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPMSELLPGGAAPTPLAPTPKLVIDLERMQQVPQEKAGPLS
                     RYVATIQSQRGDYNGRVLSIRQEDLRSLAVIYDKSPSDLTEELINWGVLDAEARRAVDA
                     F"
     misc_feature    complement(9044..9062)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            9428..10075
                     /gene="pyrR"
                     /locus_tag="B042_RS23400"
     CDS             9428..10075
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573409.1"
                     /locus_tag="B042_RS23400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_036555236.1"
                     /transl_table=11
                     /translation="MRAHDNAKGGGGAPPPPAPEGYRTVLDGPEIDRALTRIAHEVLER
                     TKGGRDVALLGIPSRGVPLARRLAERIERVEDLRVPVGSLDITMYRDDLRLAPARALGR
                     TEIPDGGLDDHVVVLVDDVLFSGRTVRAALDALGDLGRPRAVQLAVLVDRGHRELPIRA
                     DYVGKNLPTSLREGVTVCLAENDGRDAVLLGPARDRARPGAERRPETEGAGS"
     gene            10075..10983
                     /locus_tag="B042_RS0115395"
     CDS             10075..10983
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014913461.1"
                     /locus_tag="B042_RS0115395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_028649062.1"
                     /transl_table=11
                     /translation="MRHLLSSGDLTRDEATLILDTAAELARVSDRSVKKLPTLRGRTVV
                     NLFYEDSTRTRTSFELAAKRLSADVINFSAKGSSVSKGESLKDTALTLQAMGADGVVIR
                     HSASGAPHRLSHWVDGSVLNAGDGTHEHPTQALLDAFTMRSRMGRLEGLRVAVVGDITH
                     SRVARSNVLLLTTLGAHVTLVAPPTLLPVSVHTWPCEVSYHLDDVLPKSDVAMMLRVQN
                     ERMHESYFPSVREYSRNYGLDAERLACMPPDAVVMHPGPMVRGVEVSAEVADSPRCTVT
                     EQVANGVSVRMAVLYLLLGGS"
     gene            11040..12341
                     /locus_tag="B042_RS0115400"
     CDS             11040..12341
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565062.1"
                     /locus_tag="B042_RS0115400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroorotase"
                     /protein_id="WP_028649063.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 6.4e-18, bitscore:
                     56.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDTDRVYLISGARPLGGDPVDLLVADGRIADTGTGLAVPEGAET
                     VDADGLIALPGLVDLHTHLREPGREDAETVATGSRAAAMGGYTAVHAMANTDPVADTAG
                     VVEQVWRLGREAGYCDVYPVGAVTTGLAGANLAEIGAMADSAAGVRVFSDDGKCVSDAL
                     LMRRALEYVRAFDGVIAQHAQEPRLTEGAQMNEGCVSDRLGLPGWPAVAEEAIIARDCL
                     LAQHVGSRLHVCHVSTRGSVDIIRWAKARGCDVTAEVTPHHLLLTDDLVEGYDPVYKVN
                     PPLRTADDVRALREGLADGTIDIVATDHAPHPVEAKETEWSTAAMGMVGLETALAVVQE
                     TMVDTGLLTWAQVADRMSAAPARIGRVTGHGRALAPGEPANVVLYDPAAPVEADGAAMA
                     TKSSNTPFRGMTLPGRVRATFLRGVPTVLEGKIS"
     gene            12392..13540
                     /gene="carA"
                     /locus_tag="B042_RS0115405"
     CDS             12392..13540
                     /EC_number="6.3.5.5"
                     /GO_function="GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="carA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017599991.1"
                     /locus_tag="B042_RS0115405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="WP_028649064.1"
                     /transl_table=11
                     /translation="MAEETGGPAILVLEDGRVFHGRSFGAPGETFGEAVFNTGMTGYQE
                     TLTDPSYHRQIVAMTAPHIGNTGVNDDDPESGRIWVAGYVVREPARIPSNWRAQRTLDE
                     ELRRQGVVGIALTGTRALTRHLRDRGAMRAAVSTTETDPKALLTRILEQPPMAGSALAD
                     EVSTDTPYEVLPPEGTEARFHVAAVDLGIKAMTPQRLAERGCKVTVLPASATAEEILAL
                     APDGVFFSNGPGDPATADGPVAAMRGVLDAGTPLFGICFGNQILGRALELGTYKLTFGH
                     RGINQPVRDTRTSRVAVTSQNHGFAVDAPLDGPFDTPYGRAEVSHLGLNDQVVEGLRLL
                     ERPAFSVQFHPEAAAGPHDAAGLFDEFCDLMTAQSVPASEQE"
     misc_feature    15714..15728
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.77"
                     /tool="antismash"
ORIGIN
        1 gtcggtgtcc atcaagcgct gttgggggcg ggcccggcgg gccttggcgc gttggtgggc
       61 ggtggtggcc cggtagccgc gcttgctggt gttgcgggcc agctcgcggc tgatcaccga
      121 ctggtcccgg ccgaccagcc gggcgatggc tcgtacgcct tctcctcgcg cgttggcgag
      181 cgcgatctcc tcgcgttcag cgagggtgag catccgtcgt tctggcatga gcaacccctg
      241 tgacctgtga tgttgctacg acggtatgac accaccatca cctggcctga ccctggcgtc
      301 tccgcgtaca caagagactc cgcatgagtc atggtcagta gcaccagcga tccttccatc
      361 gccgcgtgag caccacggtc gaacggcagt acctggatct gcacgaacgg ccattcagcc
      421 gcctcgatga gggccttgta ctgctccctc atcacggact ttccgcctgc ggtccttcgc
      481 agagctcctt cgtccaccac gaagagcgcg agcggtgggc ggtcgcgcct caagatcttc
      541 tgtcggtcca ggcgagcctt caggagatct tcgatactac gaggtgatcg gggagggaag
      601 gccgccccca tcacggcttt cgcgtagccc ttcagtttga agaagcccag ggactgcctg
      661 ggactgaaac tcgttgatga cctgggcttt cgcttcgagt tcaacgaact tctccagcca
      721 ccacggttgg gcttgcttcg ctccgggcca caggttcagt agcgcgttgt gggcttccgg
      781 ggccttatcg gccaactcgg cgaactgttt ggagtgcctt cgatcgcctc gctcgatggc
      841 gccgacctgc tgcttggatg tgcctgtcgc tagacctagg tctttttgcg acatatcgga
      901 caaatttctt agtcgtcgga gttcatttcc aaactgggcg atagctgcgc tctcgggtag
      961 ggaagtgcgg cttggcatga ctccagcaag ccacaaaggg ccacaattgg atgcgccttg
     1021 gcgaacctgt aattcagaat ccggccacat gtagagaagg tatttgctgt tcaggcaggg
     1081 tggactccag gaaccaggag aacaagaatc ccgggtctct gagtggcgca accgcccttg
     1141 tctgttgcct ttggtcgggc agccgctcgt cagcacaaag aagtagggct gggacggcct
     1201 ccggcaagaa aaacgccccg aacccgaggg caccgggttt cagggcgtgt aagtcccacc
     1261 cgtaaccagg ttgaggtgag accacatgca gtgtacttcc ccaccctccg ctctgccgcg
     1321 ccgactgcgt ggaaccccca ccacatcggg cctcctgctc ggccccgacc tcagccacat
     1381 cgccatcgcg cggcgctggg cggcccaggc cacccgcacc cgccccggcc tggccgaacc
     1441 cctcgccctg gccgtctccg aactcacgac gaacgcgatg cgccacaccg cctccggcct
     1501 gcccggcggc accgtccgcg tcgagatcga ccgcaccggc cacctggaac tgcgcgtcac
     1561 cgacgacgga ccccgccccg acacggccac cacacccccg gcgatccccg ctctggaccc
     1621 cttccgggtg ggcggcaacg ggctgcgcct ggtcgaggcc gtgtgcgcct actgggactg
     1681 gacacgaaac cccgatggcg ggaccgccgt ccgcgccctc ttcccccgat gaccacctga
     1741 ctcccgcgcc gtgcccctgc ccccggtgcg gcgcgggatc ccgggggcgg cggacgcccc
     1801 tgccgccgcc cccttcagca ccacaccgcc gaacgagaag ggacaccgaa agtgacggtc
     1861 ctgttgtgcg gacactgcgg cagcccccgc cacggcggag ccccggccta ccgctgcgcc
     1921 tgcatccccg cccaggtgtg gcaggccccc gacctggccc gcgccgtccg cgccctggac
     1981 ctgtccaagg tcatccggta cctgcgccgc caccccgcca cccagcacca ctcccaggcg
     2041 gccctggcca gcatgtgtgg cctgtcgcag acgactctct cccgcctgga gggcggcagg
     2101 ggcgccaccc gcatcgaccg cgccgtcacc gccctggccg gactcggagc gccccaggtc
     2161 cccggcgagg tgaacaaccc gtacccggac gaggacccgc cgcccccgcc cggcccgaac
     2221 ggcggccctc ccggcgaggt cgccctcacc gtgggagcgg acggcccccg tcggctcctg
     2281 gaccacggca ccgcctgggg cgtcaccaac accccccgag gagcgaccga ctggttcgcc
     2341 ctgcccacac cggccaacca cgcactcccc aggtcgccgc atccgaaggg gaacaccggt
     2401 ccggccgttc ctgatggggc ggccccgcct ggcaccggac cgacggggcg cggcggtcct
     2461 tgggcgggcg ggggacaggg cctagggtgg tccgggtgag gaccagccac ggagacagcc
     2521 tgcgcaagca cctggacgca tccctcctgt acctgtgtac gggggcccgg agggagcagg
     2581 gcgacctcgc cgagttcgcc gacgccgccc tcgcgggggg tgtggacatc atccagctgc
     2641 gcgacaaggg cctggaggcg cgtgaggagc tcgtcgcact ggaggtgctc agggacgcct
     2701 gcgagcggca cggcgccctg ctcgcggtca acgaccgcgc cgacatcgcc cgtgcggtgc
     2761 gagccgacgt cctgcacctg ggccagcgcg acctgcccgt ccccatggcc cgcgacatcg
     2821 tcggctcgga cccgatcatc gggcgctcca acaacgacat cgaggccgcc gccgcctcgg
     2881 cgagcgaacc cggcagcgac tacttctgtg tcggcccggt gtgggcgacc cccaccaagc
     2941 cgggacgcgc cgcggccgga ctggaactgg tggagcgcgc cgcggccctg gacaccggcc
     3001 ggccctggtt cgccatcggc gggatcgacc tgtccaccat cgaccgggtc ctggacgccg
     3061 gggcacgcag ggtcgtggtc gtcagggcga tcaccgaggc cgaggacccg cgggcggccg
     3121 cggccgcgct gcgcgcacgc ctgaccgccc gggactagga cacctcacac ggccacgtgg
     3181 gagagcgcgc tcgggtggcg gcgcaggaag ccctcgatgg actgggccgg gtggccggtc
     3241 agcttgggca cggtgggcgc gaccacgtcc aactccccgg tggcgatcgc cgcgtacgac
     3301 gacgcccagc cctcgaccgc ccactcgggt gccccggtcc accggcgcga ctccagcgcc
     3361 tcctcccacg tctcgggcac gtagcggatg gtgcgcccgg tgagcgagga cagcttgtcc
     3421 accgtcgcgc ccagggtcag cgcctccggc ccggtgatgt cgtaggcggc gcccccggac
     3481 accgccgtca ccgccggatc ggtgagcacc gcggtcgcca cgtccgccac gtcgtcgcgc
     3541 gagacccagg cgacccgccc gtcgccggcc ggaccgcgca ccacgccccg gccgtccgtc
     3601 cacgtgggaa gcaggtccag gtacaggccg ggtctgagga acgtgaactc cgccccgctc
     3661 atccggatgt gggcctcggt gaagaagtgc gtgcgggcga aggtgaaggt ggacgccggc
     3721 ccggcgttca ggaaggacag gtagacgatc cgcgacaccc ccgcggcgac cgccgcgtcc
     3781 accgcgccca cgtgcgtctc gacccgcttc tcggactcgg tggccgacac caggaacagc
     3841 gtgtccaccc cccggcaggc ccgctcgaag ctccgggtgt cctcgtaggc cgccatcgac
     3901 gcgctgctgc cgggaaactc gggggcccgg ttgatgtcgc ggacgatgag tcgctgcgcc
     3961 agccccagcc gggcgatccg ggcggcgacc cgcccgccca ccgcgccggt cgctccggtc
     4021 acgcctatgg tgtggtttgt catgtgatcg tcgcccatga caccccatcc tgagggatcg
     4081 gaccgcagcg accggccagc ggcacgcgcg tttttaccgg ttccggtcga cgggtggcgc
     4141 gctcttggcc tcacccgcgc cgcggtaggc caggcgccgc agcaggacct ccgcggggcc
     4201 gcgccgcccg gcgcgctcca gcagcgcggc ggccacgacc gtcaccagcc acaccccgac
     4261 ggcgaacagc agcatgctcc acgacgtcag gtgcgctccc agtcccagcc cccacgcggc
     4321 caggaccggt gcgcacagga ccgactgcgc caggtaggcc gacatcgagc gcttgccggt
     4381 cgccgcgagg gcacccgcca ccggtcccgt gccccgaccg cgctcgatcc ggtgcgcgat
     4441 cagggcgatc gcggcgacgt agcccagacc gccggccagg ccggtgacca tgtgcggcag
     4501 ggacaggagc agcccctggc cctccgacag gtcccagaag ccggtctggg ccagggcgag
     4561 gggcaggccg ccgatccatc ccgtcgcgag gccgccgacg gccacggcgc gcagcaggcc
     4621 cacgttccgc cccggctcct ccaggacccg gcgccgcgcg gcccagaagc cgagcaggat
     4681 cgcggcgggc acggccatgc ccagcaggcc ctgccccagg gtgacgacgg gccagtaggt
     4741 gaggcgctcc acgaccgagg cgaggtagga ggggtcggag atgctggccg ccatgtcctc
     4801 ctgcccgaac gactggcccg ccatctcctc ggggggcacg aaggccagac tcagcagcga
     4861 cagcgcggcc agggccgcca tcagggcggt gaggagtccg gcccacacca gcagggtcgc
     4921 gttccggcgc cgcaggaaca gccaggccag caccagcccg gccagtccgt aggcccccag
     4981 gatgtcgccc acccacagca gcagggcgtg caccaggccg aacaccagca gccacaggtt
     5041 gcggcggcgc agcaccgcgt ccgcctcgcg gggcgagacc cccgcggcct cctgtctgcg
     5101 ggtcagttgc accatgccgt acccgaacag gaacgcgaac atcggatagc tgcgcatgtc
     5161 gatcgcggcc gtggtgacga actgcgcgat gccgtccgcg gggccctccg gcgcggggtg
     5221 tgcgctcgcc ccgctcatcg gcagggccca caggtaccag gtggcgttgg cgatcgcgat
     5281 gaaggccagc atggacccgc gtgccaggtc tggcgccagt gagcgctccc cggtttcggt
     5341 cgggccgcgt gaggcggtgt gtgtggacat gggcatccct ccggtgtcgc gatatgtcgt
     5401 gtttgcgatt caaccggagc gtcgggatgg ttacaagacg cccacgacgg tcggggaccc
     5461 ggggaaaccc cctaaggaga tccccgggtc agtgcgtgcg cgaggtggcg gcgtccacca
     5521 accaccgcag gggctcgcgc gccgacccgt ccagctcggg actctccaga gccgacagcg
     5581 cctgctcgga gtactcctcg atgagccgtt cacacgcctt gagcgcccct gagtcctcga
     5641 tgagcgcgca catccactcc accgaggcct ccgacaggtc cggtgtgccc agcagggagc
     5701 ggaagcggtc ggccgcaccg gagtcggcgc gctccagggt ctcggccacg accagggtcc
     5761 gcttcccctc gcgcaggtcg tcgccggcgg gcttgccggt ggtaccgggg tcgccgaaga
     5821 ccccgagcac gtcgtcgcgc agttggaagg ccacgcccag cggcatcccg tagccggtgt
     5881 agacaccgcc caaggcgtcc aggcgcccgg ccagggccgc gcccaggtgc agcggccgct
     5941 cgatcgtgta cttggccgcc ttgtagcgca tcacccgcag cgccgcctcg cggctctccg
     6001 tgccccggac ctgttcgagc gtgtccaggt actgccctgc catcacctcg gtgcgcatgg
     6061 cgtcgaaggg cgcccgcccg ccctggagca cctccggtgc gaacccgctg gcctggtaca
     6121 tctcgtcgga ccaggccagg cagaggtcgc cgatgaggat cgccgcgccc tccccgaagg
     6181 agtcggcgtc gccgctccag ccgtgctcgg tgtggagcgc ggccagcctc cggtgcgtgg
     6241 cgggcaggcc gcgccgggtg tcgctgcggt cgatcacgtc gtcgtgcatc agcgcgcacg
     6301 cctggaggaa ctccagggag gccgccgccc ggaccacgcg tgcgtcgccg tcggcgccgc
     6361 cgcccccgcg ccaaccccag tagcagaacg tggggcgcag ccgcttgccg cccgagagca
     6421 tcgcctccag ggcgtccatg gccggggcca gctcctcgcc gatctccagc aggcgggtcc
     6481 ggtgcgaggc gcagaacgag acgagttctc cgtccaccgc cgagcggacc acggagacgg
     6541 gcgatgggga agcgaaaggg gccataacca gcacactagc ggcttccggg ccacaggatg
     6601 ccgggttcgg cgcaacccgg ccccccgtcc gcctgccggt ccgtgcggtg tgcgtcaccg
     6661 tgtctcacgg aagcgggagg ctccccgcgc cgcgctgtcc gggctcgcct aaggtggtgt
     6721 ccatgctcgc tgcaccgact cagcccgcag ggccgcaccc gcccgccgcg cgcccgcgtc
     6781 agatccgtga actcctcgac acgggcgagc ccctgttctc cttcgagttc tttccgcccc
     6841 gcggtccgaa gtcccaggcc cggctgtggc gggcgatccg cgagatcgaa gcgctcggcc
     6901 cctccttcgt ctcggtcacc tacggcgcgg gcggcggcac gcgcgacctc acggtggaga
     6961 ccaccgagcg catcgcggcc gacaccacgc tgctgcccgt cgcgcacatg acgctggtgg
     7021 accactcggt ggccgagctg cgccacctca tcggccgctt ctccgccgcg ggcgtgtcga
     7081 acatgctggc cgtgcgcggc gaccctcccg gcgaccccgg cggtccgtgg gtccgccacc
     7141 cgcagggcct gacctacgcc gaggaactgg tccgcctgct caaggacagc ggtgacttca
     7201 gtgtgggcgt ggcggccttc ccgcacaagc acccccgctc cgacgacgtc gagaccgaca
     7261 ccgaccactt cgtgcgcaag tgcgaggccg gggcggacta cgccatcacg cagatgttct
     7321 tcgacccgga ggagtacctg cggctgcgcg acagggtggc cgcccggggg tgcggggtgc
     7381 cgatcattcc cgaggtgttc ccggtggtca ggagggccac gatcgagcgg tccgagcagc
     7441 tctcgggcgc gcccttcccg cgtgatctgg ccgagcggtt cgagcgcttc ggcgacgacg
     7501 ccgaggccgt ccgcgccttc ggtatcgagc acgcccagcg catgtgcgag cggctgctgg
     7561 ccgagggggc tccgggcatc cacttcatca ccttcaacca gtccaccgcc accagggaga
     7621 tctaccgcga ggtcgccggc caccgggcgg gcccagcgga agccgcgcgg ccatgacgga
     7681 gaagggctga gccgggctcc cggggaagga gaagtcctcc aggatctccg tgaagccgca
     7741 ggagctgtac aggtggcgtg ccgcggtggg gccggtacga gtggacagca ccgcggtgcg
     7801 ctcgggccgg cccgagcaca gggcgtggag cagggacctg cccacacccc ggttctgctc
     7861 gtcggggtcc acgtgcacct cggcgatctc cagtgtgtcc gacaggtagc ggtgcgccag
     7921 gcgcgccctg ccccgggcgc gcatcgcctc ggtgacgacg tcgtgccacc actggccccg
     7981 cccgccgtgg aagccgtagg cgaagccgac cggccgctcg ccgcgcacgg ccaccaccga
     8041 gcggaatccc ggatagcgcg cgtgaccgct catcacggcg gcccggccgg gcagttggtc
     8101 ctccgggggg cgcatcgcgc ggtcgtagac gcccagcagg acggggacgg catgggcgaa
     8161 cgcaggaggg gccagttcgc gcagttcggt gtcggctgcc accgtcccac tctagggcgt
     8221 gggcccttcg gctccgcgag cacgggttga cgggtgcgtc ggggctgggg ttaactggtc
     8281 ttggtcgaac gtgagttcga taagggtgcc ggtgcggccg gggcggggag gggaagcccc
     8341 gtgcacggcc gcaccgtgcc ccgcgcacac gggagccggc gccctcaggg cgccggctcc
     8401 cgtgtgcgcg ggaggccccg aaccggggcc ggggctcaga aggcgtcgac cgcgcggcgc
     8461 gcctcggcgt cgaggacgcc ccagttgatg agctcctcgg tgaggtccga cggcgacttg
     8521 tcgtagatga ccgccagtga gcgcaggtcc tcctggcgga tggacagcac ccgcccgttg
     8581 tagtcgccgc gctggctctg gatcgtggcg acgtagcggg acagcgggcc ggccttctcc
     8641 tggggcacct gttgcatgcg ctccaggtcg atgaccagct tgggcgtcgg ggccaggggt
     8701 gtgggcgcgg cgccgccggg cagcagttcc gacatgggaa cgccgtagaa gtcggccagt
     8761 tcggcgagct tctggacggt gacggcacgg tcgccgcgct cataggagcc gaccacgacg
     8821 gccttccagc gcccgtggga cttctcctcc acgccgtgca gggagaggcc ctgctgggtg
     8881 cggatggcac gcagccgcgc gccgagggac ttcgcgtatt cggatggcat cttcttgtcg
     8941 ctcccggccg tgacggtggc tggtgtggtg ggggaggcgt ccggccttcc tcggcggccg
     9001 ccgaggcggt cgttcggagg gtcgcggggt gcaaccccac ccagcagtgg ttacagacag
     9061 tgacgctagg gcggtccggc ctccaggtca agccgttggg gtgaaacgcg actaatcagt
     9121 atccaaaccg tgcgtaagtg agactcctct catgtccgga ccgaaccgga ttagtggtgt
     9181 gtaccggtca cgcagagccc cgacaccgca gggatttcct ggcacgcggc gggtgccggg
     9241 gccgcgctcc cggatccgcg ggcacggccc cggcgctcca ccgcgcgttt cccgcgtgtc
     9301 gggcctcaca cggcacgtgc ccggtcccgg ggccgtcagt cgagggactc ggggggccgc
     9361 tggtagcgtt gggccgatcg acatccttta acgacctgtt cagtgaggca gggaaggggt
     9421 cactactttg cgtgcgcacg acaacgcgaa aggtggcgga ggtgctccgc cgcccccggc
     9481 acccgagggg tacagaaccg tcctcgacgg cccggagatc gaccgggcac tcacccgcat
     9541 cgcccacgag gtgctcgaac gcaccaaggg cgggcgggac gtcgccctcc tgggcatccc
     9601 ctcccgcgga gtccccctcg cccggaggct ggccgagcgg atcgaacgag tcgaggacct
     9661 gcgcgtcccc gtcggatccc tcgacatcac catgtaccgc gacgacctca ggctcgcgcc
     9721 cgcccgggcc ctgggccgca ccgagatccc cgacggcggc ctcgacgacc acgtcgtcgt
     9781 cctcgtcgac gacgtgctct tctccggccg caccgtccgc gccgccctgg acgcgctcgg
     9841 cgacctcggc cgcccacgcg ccgtccagct cgccgtcctc gtcgaccgcg gccaccgcga
     9901 actgcccatc cgcgccgact acgtgggcaa gaacctgccc acctccctgc gcgagggcgt
     9961 caccgtgtgc ctggccgaga acgacggccg cgacgcggtc ctgctcggcc ccgcccgcga
    10021 ccgggccaga cccggagctg agcggcgccc cgaaaccgag ggggcgggct cctgatgcgc
    10081 cacctgctct ccagcggcga cctcacccgc gacgaggcca ccctcatcct ggacaccgcc
    10141 gccgaactcg ccagggtcag cgaccgttcc gtcaagaagc tgccgaccct gcgcggccgg
    10201 accgtcgtca acctcttcta cgaggactcc acccgtacac gcacctcctt cgagctggcg
    10261 gccaagcgcc tgtccgccga cgtcatcaac ttctccgcca aggggtcgag cgtctccaag
    10321 ggagagagcc tcaaggacac cgccctcacc ctccaggcga tgggcgccga cggcgtcgtc
    10381 atccgccaca gcgcctccgg ggcgccgcac cggctctccc actgggtcga cggctcggtg
    10441 ctcaacgccg gggacggcac ccacgagcac cccacccagg ccctcctgga cgccttcacc
    10501 atgcgctccc gcatggggag gctggagggc ctgcgcgtgg cggtcgtcgg cgacatcacg
    10561 cacagccgcg tggcccgctc caacgtgctc ctgctgacca cgctcggagc gcacgtcacc
    10621 ctggtcgcac cgcccaccct gctgccggtc tctgtgcaca cctggccctg cgaggtctcc
    10681 taccacctcg acgacgtgct gcccaagtcc gacgtcgcca tgatgctgcg cgtacagaac
    10741 gagcgcatgc acgagtccta cttcccgtcc gtgcgcgagt acagccgcaa ctacggactg
    10801 gacgccgaac gcctcgcgtg catgcccccg gacgccgtcg tcatgcaccc gggcccgatg
    10861 gtccgcggcg tcgaggtctc cgccgaggtc gccgactccc cgcgctgcac cgtcaccgag
    10921 caggtcgcca acggcgtgag cgtgcgcatg gccgtgctct acctgctgct cggcggctcc
    10981 tgaccggacc cgcccctctc gacttcccgc atccacgaac acgaggactc cacaccgtca
    11041 tgcccgacac cgaccgcgtc tacctgatca gcggggcccg accgctcggc ggcgaccccg
    11101 tcgacctgct cgtcgccgac ggacggatcg ccgacaccgg aaccggcctg gccgttcccg
    11161 agggcgccga gaccgtcgac gccgacgggc tgatcgccct gcccggcctg gtggacctgc
    11221 acacccacct gcgcgagccc ggccgcgagg acgccgagac cgtcgccacc ggctcccgcg
    11281 ccgccgcgat gggcggctac accgccgtcc acgccatggc caacaccgac ccggtcgccg
    11341 acaccgccgg ggtcgtcgaa caggtctggc gcctgggacg cgaggccggc tactgcgacg
    11401 tgtatcccgt cggcgccgtc accaccggac tggccggtgc caacctcgcc gagatcggcg
    11461 ccatggccga ctccgccgcc ggggtccgcg tcttctccga cgacggcaag tgcgtctccg
    11521 acgccctgct catgcgccgc gccctggagt acgtcagggc cttcgacggc gtgatcgccc
    11581 agcacgcgca ggagccccgc ctcaccgagg gcgcccagat gaacgagggc tgcgtctccg
    11641 accgcctggg cctgcccggc tggcccgcgg tcgccgagga ggcgatcatc gcccgcgact
    11701 gcctgctcgc ccagcacgtg ggctcgcgcc tgcacgtgtg ccacgtctcc acccggggct
    11761 cggtcgacat catccgctgg gccaaggccc gagggtgcga cgtcaccgcc gaggtcaccc
    11821 cccaccacct gctgctcacc gacgatctgg tggagggcta cgacccggtc tacaaggtca
    11881 acccgccgct gcgcaccgcc gacgacgtcc gcgcactgcg cgagggcctg gcggacggaa
    11941 cgatcgacat cgtggccacc gaccacgcac cccacccggt ggaggccaag gagaccgagt
    12001 ggtccaccgc cgccatgggc atggtggggc tggagaccgc gctggcggtc gtccaggaga
    12061 ccatggtcga caccggcttg ctcacctggg cccaggtcgc cgaccggatg tcggccgccc
    12121 cggcgcgcat cggacgggtc accggccacg ggcgcgccct ggcccccggg gagcccgcca
    12181 acgtcgtcct gtacgacccc gcggctcccg tcgaggccga cggcgcggcc atggccacca
    12241 agagcagcaa cacccccttc cgggggatga ccctgcccgg ccgagtccgc gcgaccttcc
    12301 tgcggggggt cccgaccgtc ctggagggga agatcagttg aacacagcag cacacagccg
    12361 gctcggagcc ggcaccgtga agggggagaa cgtggccgag gagaccggcg gaccggcgat
    12421 tctggtactt gaggacggcc gcgtgttcca cggccgctcc ttcggcgccc ccggggagac
    12481 cttcggcgag gccgtcttca acaccggcat gaccggttac caggagaccc tcaccgaccc
    12541 ctcctaccac cgccagatcg tggcgatgac cgctccgcac atcggcaaca ccggcgtcaa
    12601 cgacgacgac cccgagtccg gcaggatctg ggtcgccggg tacgtcgtcc gcgagcccgc
    12661 ccgcatcccc tccaactggc gtgcccagcg caccctcgac gaggagctgc gccgccaggg
    12721 cgtggtcggc atcgccctca ccggcacccg tgccctcacc cgccacctac gtgaccgcgg
    12781 tgccatgcgc gcggccgtca gcaccaccga gaccgacccg aaggcgctgc tcacccgcat
    12841 cctggagcag ccgcccatgg ccgggtccgc tctggccgac gaggtcagca ccgacacccc
    12901 ctacgaggtc ctgccgcccg agggcaccga ggcccgcttc cacgtcgccg ccgtcgacct
    12961 gggcatcaag gccatgacgc cccagcgcct ggccgagcgc ggctgcaagg tcaccgtgct
    13021 gcccgcctcc gccaccgcag aggagatcct cgcgctggcc cccgacggcg tgttcttcag
    13081 caacggcccc ggcgaccccg ccaccgcgga cggccccgtc gccgccatgc gcggtgtcct
    13141 ggacgcgggc acaccgctct tcggcatctg cttcggcaac cagatcctgg gccgtgccct
    13201 ggaactgggc acctacaagc tcaccttcgg gcaccgcggg atcaaccagc ccgtgcgcga
    13261 cacccgcacc agcagggtcg ccgtcaccag ccagaaccac gggttcgccg tcgacgcccc
    13321 gctcgacggc cccttcgaca ccccctacgg acgggccgag gtcagccacc tcggtctcaa
    13381 cgaccaggtc gtcgagggcc tgcggctcct ggagcgcccc gcgttcagcg tccagttcca
    13441 ccccgaggcc gctgcgggcc cccacgacgc cgccggtctc ttcgacgagt tctgcgacct
    13501 gatgaccgcc cagtccgtac cggcctccga gcaggagtag aggaagaaca tgccgcgccg
    13561 tagtgacctt tcatccgtcc tcgtgatcgg ctccggcccg atcgtgatcg ggcaggcggc
    13621 cgagttcgac tactcgggca cccaggcctg ccgggtcctg cgggccgagg gcctgcgggt
    13681 catcctggtc aactccaacc cggccacgat catgaccgac ccggagatcg ccgacgccac
    13741 ctacgtcgag ccgatcacca ccgagatgat cgagaagatc atcgccaagg agcaccccga
    13801 cgcactgctg cccaccctgg gcgggcagac ggcgctcaac gccgccatcg ccctccacga
    13861 ggcgggcatc ctcgacaagt acggcgtcga actcatcggc gccaacgtcg aggccatcca
    13921 gtccggcgag gaccgcgagt ccttcaaaca gatcgtggag cgcatcggcg gcgagtccgc
    13981 gcgctcccgc atctgccaca ccctccagga gtgcctggac gccgccgagg aactggacta
    14041 ccccgtcgtg gtccgcccct ccttcaccat gggcggtgcc ggatcgggct tcgcccacga
    14101 cgcaggcgaa ctgcgccgca tcgcgggcca gggcctggcg ctctcaccga ccaccgaggt
    14161 gctcctggag gagtccatcc tcggttggaa ggagtacgaa ctggagctga tgcgcgacgc
    14221 caacgacaac gtcgtggtcg tctgctccat cgagaacctc gaccccatgg gcgtgcacac
    14281 cggcgactcc attaccgtcg cgcccgccat gaccctcacc gaccgcgagt accagaagct
    14341 gcgcgacctg ggcatcgcgg tcatccgcga ggtcggcgtg gacaccggcg gctgcaacat
    14401 ccagttcgcc gtccaccccg agagcggccg cgtcatcgtc atcgagatga acccgcgcgt
    14461 gtcccgctcc tcggcgctgg cctccaaggc caccggcttc ccgatcgcca agatcgccgc
    14521 caagctcgcc gtcggctaca cgctcgacga gatccccaac gacatcaccc gggagacgcc
    14581 cgccagcttc gagcccgcgc tcgactacgt ggtcgtcaag gtcccgcggt tcgccttcga
    14641 gaagttcccg ggcgccgacc ccaccctcac caccaccatg aagtcggtcg gcgaggccat
    14701 ggcgatcggc cgctccttcc ccgaggccct ccagaaggcc atgcgctcgg tagagaaggc
    14761 cggagtcggg ttcacctggg ccggagagcc cgaggacaag gacggcctgc tgcgccgggc
    14821 cgccatcccg accgagcacc gcctgcgcca ggtccagcag gccctgcgcg ccggggcgac
    14881 ggtccaggag ctgtacgagg ccacccggat cgacccctgg ttcctcgacc agatgctccg
    14941 cgtcgaggag accgcccggg ccctggccca ggccccccag ctcgacgccg ccctgctgcg
    15001 cgaggcgaag gggctgggct tctccgacgt ccagatcggc gagatcaccg gcaagagcga
    15061 gaccgtcgtc cgcgaactgc gccacgccct gggcgtccac cccgtctacc tgaccgtgga
    15121 cacctgcgcc gcggagttcg ccgcgcagac gccctacctc tactccagct acgacgagga
    15181 gaccgaggtc cccaccgggg acaagcccaa gatcatcatc ctgggctcgg ggcccaaccg
    15241 catcggccag ggcgtcgagt tcgactactc ctgcgtccac gcctccttcg cgctctccga
    15301 ggccgggtac gagaccgtga tggtcaactg caaccccgag acggtctcca cggactacga
    15361 caccagcgac cggctctact tcgagccgct caccctggag gacgtcctgg aggtcgtccg
    15421 cgccgagcag gccgccggac cggtcgccgg ggtcatcgtc cagctcggcg gacagacccc
    15481 gctgggcctg gcccagcgcc tcaaggacgc cggggtcccc gtcatcggga ccagccccga
    15541 ggccatcgac ctggccgagg accgcggcga gttcggcgcg gtcctagccc aggccgggct
    15601 gcccgcgccc aagcacggca ccgcctactc cttcgccgag gccaaggccg ccgcggacga
    15661 gatcggctac ccggtgatgg tccgcccgtc ctacgtgctc ggcggacgcg ggatggagat
    15721 cgtctacagc gaggagatgc tcgccgacta catccggcgc aacgcccagg tcagcccgga
    15781 gcacccggtg ctcatcgacc gcttcctcga cgacgccatc gagatcgacg tcgacgcgct
    15841 ctacgacggc accgacctgt acctgggcgg cgtcatggag cacatcgagg aggccggtat
    15901 ccactccggc gactcggcgt gcaccctgcc ctcgatcacc ctgggcagcg aggacgtcga
    15961 gcgcatccgc tactccaccg aggccatcgc ccgggggacc ggtgtgcggg ggctgctcaa
    16021 cgtccagtac gcgctcgcct ccggcgtcct gtacgtgctg gaggccaacc cgcgtgcctc
    16081 ccgcaccgtg cccttcgtgt ccaaggccac cgcggttccg ctggccaagg ccgctgcccg
    16141 ggtcatggca gggagcacca tcgcgcaact gcgcgccgag ggcatgctgc ccgagcgggg
    16201 ggacggcggc gacctgcccg ccgacgcccc ggtctcggtc aaggaagcgg tgctgccctt
    16261 caaccggttc atcgacaagg agggcgaggg ggtcgacacc atcctcggcc cggagatgcg
    16321 ctccaccggc gaggtcatgg gcctggacgt gcagttcggc gccgcctacg ccaagtcgca
    16381 gtcggccgtc accggcagcc tgccctcgca gggccgggtg ttcgtctcgg tggccaaccg
    16441 cgacaagcgc tcgatgatct tcccggtcaa gcgtctggcc gacttgggat tcgagatctt
    16501 ggccacggag ggcaccgccc tggtcctgcg ccgcaacggc gtgcacgcca ccgtcgtgcg
    16561 caagc
//
