LOCUS       NZ_AZXF01000018        14137 bp    DNA     linear   CON 21-OCT-2024
DEFINITION  Nocardiopsis sp. CNT312 B042DRAFT_scaffold_12.13_C, whole genome
            shotgun sequence.
ACCESSION   NZ_AZXF01000018
VERSION     NZ_AZXF01000018.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nocardiopsis sp. CNT312
  ORGANISM  Nocardiopsis sp. CNT312
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsidaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 149806)
  AUTHORS   Jensen,P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R41043
            investigation_type                :: bacteria_archaea
            project_name                      :: Nocardiopsis sp. CNT312
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi14643
            Funding Program                   :: DOE-CSP-ICBG 2011
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000515115.1-RS_2024_10_21
            Annotation Date                   :: 10/21/2024 21:26:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,296
            CDSs (total)                      :: 4,234
            Genes (coding)                    :: 4,144
            CDSs (with protein)               :: 4,144
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 23 of 90
            Pseudo Genes (incomplete)         :: 74 of 90
            Pseudo Genes (internal stop)      :: 5 of 90
            Pseudo Genes (multiple problems)  :: 12 of 90
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:21:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14137
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AZXF01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..14137
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..14137
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14137
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[3090:4137](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3091..4137)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(231..245)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(432..452)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            907..2157
                     /gene="hisS"
                     /locus_tag="B042_RS22420"
     CDS             907..2157
                     /EC_number="6.1.1.21"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisS"
                     /inference="COORDINATES: protein motif:HMM:TIGR00442.1"
                     /locus_tag="B042_RS22420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine--tRNA ligase"
                     /protein_id="WP_197024215.1"
                     /transl_table=11
                     /translation="MAQRPSPVRGMRDVLPDAAERRQWLESTIHHEFSRFGYRPIETPA
                     LEDLRFLESGQGGDNEKLIFKTLRRGISLDGVTDVASLADSGLRFDLTVPLARFYATNA
                     PSLPSPFRAVQIGPVWRAERPQRGRYRQFTQCDIDILGEASLLAEIELLSAGSRALAAV
                     GLAEFTVRLNHRRLLTGLLTVCGFANETHANVLIVVDKLDKIGVEGVERELAEAGHPRS
                     AITTLSEVLAKAESATEPDQLAQVLPSGMDEEPLEELRTIAAAVVLPEAAHKARLVMDL
                     SLVRGMGYYTGPIFEVAAPGLGSSIAGGGRYDEMIGRIGGRPTSACGFSIGFERLAEVL
                     DSAAVRRESRVALLWRSEQDLAQVTTHADRLRADGYVVETVHVGGKGKGVYKRLAAAGF
                     DLVAQALDGAEPRPLSS"
     gene            2154..3089
                     /locus_tag="B042_RS0108650"
     CDS             2154..3089
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS0108650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="phosphotransferase family protein"
                     /protein_id="WP_028647961.1"
                     /transl_table=11
                     /translation="MNTARPRWGDLPAAVRRKVTRFLGEEVVSEEPQDGGYTPAMASLL
                     TTSSGRALFCKAMPEKHPLCATLAAEAAVAASAPAGAALPGLVWEGTEDGWRVVVFTAV
                     RGRHANLSPGSDDVAAVVSALDGLAGDLTPCPFSTAPTAREALSPLLSGWSSLQEQPPP
                     ELDPWALANLERLAALEETWADHAGGDTLTHGDIRADQLLIDVQERVWVVDWAYPCRGA
                     AWIDAVDLVTPLIMNGHTPEAAEKQVAGSARFATAPAAAVTSFAVAAAGYWARVCRQAP
                     PPGPGGVRLRAFQARAADAALAWVRHRLGE"
     gene            complement(3091..4137)
                     /locus_tag="B042_RS0108655"
     CDS             complement(3091..4137)
                     /EC_number="4.2.3.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="B042_RS0108655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class 1 isoprenoid biosynthesis enzyme"
                     /protein_id="WP_028647962.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.8e-25, bitscore:
                     80.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTTTLDRFSPPLGALWTRTLTHWTQNLPPHLAGLGQDYLAYAQV
                     DSLLPRPVLTLVGSAHDHTELPDDLVERLGTVALVPQVVRDLFAIHDDIVDGDTEKFGH
                     PTLPEAFRRRIGTAGNGAALFWADLLLSLARNLLNDADPQHRAPLWDVVVECVRRTQHG
                     QLQELLWQRDLESITTDAIVRMYQDKAGDYCYGLPWRIGHTATGADPAQREAVARILET
                     IGAASQIVDDLATGCPDLMEAGKDDPAEIRHLRRTLLLVELHQRLPDDHRLRPVIEGDH
                     ATDEQVEEIRLAFTTTGAIQAAARTAADLVEQALRDLSRVGIGAAARAYISDLAQQRVL
                     HELRPVLA"
     gene            complement(4131..5468)
                     /locus_tag="B042_RS0108660"
     CDS             complement(4131..5468)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024785.5"
                     /locus_tag="B042_RS0108660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP phosphoribosyltransferase regulatory subunit"
                     /protein_id="WP_028647963.1"
                     /transl_table=11
                     /translation="MPHTPRNTQPFVGTRDRFGPELRQRDYTQSVLAQYAHTRGYDRLE
                     VPALERKASFSRQVVGASPWPEWNPKGVFELDVPDYGPGHTHTHQNTPAVLIPEGTVSV
                     ARWLASVLPTQTLPLKVFYDLPCWRNEAVDTLSPGKAREFRQFGVEILGVASAAADAEI
                     ITFIVGALRSLGTPGNAVRVRISDVGVFRALAERSGFDETTTVAVKECLDALAECRAGK
                     DPDRTSGLDTRLDALLADHPAETVERWRAMAHHVSGDVDPGLLAALGDVAPGHLERLSS
                     TAQALRQAGLNVAVDLGVVRSHEYYTGLAFEVDVVLPGGSFVEIAGGGRYDHLIGHFAA
                     NGPGTVPASGFAFGIERLLAVMDACGTFTDTPNHQRAHHFGHSTADRLLVPKPTGDPVR
                     DYLRAYATTSDHIDGRRVDLWVGEATDTDAIGRYAQARQIPETTSC"
     gene            complement(5628..5840)
                     /locus_tag="B042_RS22425"
     CDS             complement(5628..5840)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017600946.1"
                     /locus_tag="B042_RS22425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BldC family transcriptional regulator"
                     /protein_id="WP_051415552.1"
                     /transl_table=11
                     /translation="MTPLNSDNTSASLEALIPAEVAALFRVDSQTVTRWAKEGRISSFR
                     APGGHRRYLRSEVDALWTERLTPAN"
     gene            complement(5837..6133)
                     /locus_tag="B042_RS22430"
     CDS             complement(5837..6133)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017574955.1"
                     /locus_tag="B042_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_051415553.1"
                     /transl_table=11
                     /translation="MSTPLTDSRAFCRDLPDPDRLFGNTLQQHRARHICAPCPIRTACL
                     AEALELRIDSGLWGGMTARERRALRLRNPQVDDWRAHLAPLQPTTHIREEPAR"
     gene            complement(6130..6444)
                     /locus_tag="B042_RS22435"
     CDS             complement(6130..6444)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS22435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_036554354.1"
                     /transl_table=11
                     /translation="MITVAWNVRDDHDQYMAARQLQLRRRSRWLVMWGPGSRAFFAFYR
                     GSAPVAPLFASTGQELHRQILHVETDLATTAPADRSRPEPACSRTPCTPAHHHFTRPPT
                     "
     gene            complement(6441..7007)
                     /locus_tag="B042_RS22440"
     CDS             complement(6441..7007)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="B042_RS22440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_155988970.1"
                     /transl_table=11
                     /translation="MAALVEQAKNTETDTGNREVPPLPKRATAPSDRAPVLLEPHDEFT
                     GSAMTVPGEPAYAKIMRRRLRTLASLPDWELRPIELLASELFNNCIRHTRSGDPGGEIT
                     ISVFKLAGRTQVRITDAGPRDGEITVPHLRPLDPDDESGRGLHLVATGASRWGTIHHDD
                     GRTSVWFEVDRIDRNLARPADHTEW"
     misc_feature    7120..7133
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.14"
                     /tool="antismash"
     misc_feature    complement(7194..7208)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.46"
                     /tool="antismash"
     gene            7287..9323
                     /locus_tag="B042_RS24875"
     CDS             7287..9323
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013775.5"
                     /locus_tag="B042_RS24875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase"
                     /protein_id="WP_155988972.1"
                     /transl_table=11
                     /translation="MCIPKGFWEIPEAQEAAGHLDAGSLVRLLRSRTNLSQEALGRLTG
                     LSQSMVSQLESHKRELKDVVKLRRFLDGLGAPRVTATRTQRESIESTRLLAHAAQVTMG
                     AAEIDPHRWRGPNMPEAALPVRRVTGTDVDHVETVTKALRAADYRLGGGACLDAIMAHL
                     AYAHRLLRAAKPGNQVGLQLYRAVADLHNLAGWASFDVGRYKVAAEHLSLALEQARYIE
                     EPSLVANVLYRMGRLHLHRGHTLQALRFLQLGQIAAQDSGCERTVALMCANAAWAYAVL
                     DDHKRSMDSLARAHDAFARADADTTPWVRFFREADLDAMSGVVNAALPTPSLGARHRPA
                     RPTPASRSGLPAPGRDRRTRRRDCYSSHIMSTTPAPSTSPRFALTRDRVHDVLAALCEE
                     AGLGAKAAGDAELIKFTNNAVYRLPRVGLVVRIAGSATVAERVPVVIQAARWLAQHDAP
                     TVRLVEDIPQLVRVGGATATFWHLVPSTGPEPTGTDLGRILRRLHALPAPGFALPSWEP
                     FARIRSRIADAEGLAEADRVFLTERTDHLELLVQDLEFELPAGVLHGDPFMGNLIPGPN
                     GPVICDFDSLSHGPREWDLIPAAVGKVRMDYPTDHHSPLAAEYGFDVLTWPGFPVLRQL
                     RELRLVTSVLPVLNTNPGLRTQWRHRLDTLQRSDTTTRWSTYR"
     gene            complement(9506..9844)
                     /locus_tag="B042_RS25615"
     CDS             complement(9506..9844)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B042_RS25615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155988974.1"
                     /transl_table=11
                     /translation="MTVLGFGRFHRVDRGPVVVKSAGEGVQAGRIVLTNVGDPRGQVLG
                     VARGGFQEPGEAADVVGQPRYLRACLGQLGESLALFGCEPFGAGQEKLAEGLGRDRLPV
                     AVEQARAG"
     misc_feature    10254..10268
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.97"
                     /tool="antismash"
     misc_feature    10478..10498
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.54"
                     /tool="antismash"
     gene            10479..11336
                     /locus_tag="B042_RS0108695"
     CDS             10479..11336
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024967.5"
                     /locus_tag="B042_RS0108695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="O-methyltransferase"
                     /protein_id="WP_197024217.1"
                     /transl_table=11
                     /translation="MSQFSEYRDFRSGALDRAVYSKLIEQSSDELLEAGLNRDQMNLST
                     RFPLDDLAFVKETITSLRQQSVLPDRDFSTSGYSDWERLVASLYDHGGNMTYIFPEEAL
                     LIHALASVIKPRHAVFAGSYYGFWAIWAVREVVAAGGEVTLIDTDDTVMHLAQRNFERL
                     GVSENVNFVVADAISYSRAELADIDFVALDAEGPKSCADEDLRDKAIYYPITQAIAPAM
                     LPGAILLAHNVLLENVTQNAYFEERIAYNELQYARWHSFLSEQFDFRISYPSTEGVGIY
                     RKAR"
     gene            11336..12286
                     /locus_tag="B042_RS0108700"
     CDS             11336..12286
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF023015.5"
                     /locus_tag="B042_RS0108700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diiron oxygenase"
                     /protein_id="WP_231493895.1"
                     /sec_met_domain="AurF (E-value: 8.9e-27, bitscore: 87.1,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGSTGLAVGCQAQFSCPKELFRTGASEEPQNDYRSPFRDWHERA
                     SVRKEPRRVLSPSDDRYLLFDADLVPTSSHILVQELPDPQRNEVLTQHLYRYLKFTTQL
                     EQLVVNKTMLDIAYGRIGVDLPRGMVFDAHKIYCDEAYHALFSMDMYRQVIDATGVAPR
                     IGSDPHFFRRLRRLLEDVDPSMRLLVELLFVFCSETLISGTLDSGRDQQVDPAVHEMVK
                     DHAKDEGKHHAYFASFLFHLCPQIHTKYQESAAALIPDLIMTFLEPDRESLVSELCGYD
                     LSQDEAEQVVAETFTRDVVRDIRAGDRASHTQILP"
     misc_feature    11354..11356
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12343..12356
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            12356..12859
                     /locus_tag="B042_RS0108705"
     CDS             12356..12859
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024812.5"
                     /locus_tag="B042_RS0108705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_028647967.1"
                     /transl_table=11
                     /translation="MTGAYAIRPAEISDLEGIREILNHFIRTSDATLDYDEKSEADMES
                     WYKSHNDRYPVYVCHEESGRVVGYASLSPFAARAGYQASAEISVYVREEAQSRGTGIAL
                     CERMTSLGMETGFTAITAIMTSTNKPSIRMVEILGYQRTGSLRNIGAKFGRPVSLEIYQ
                     IYPQ"
     gene            12967..13983
                     /locus_tag="B042_RS0108710"
     CDS             12967..13983
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013539.5"
                     /locus_tag="B042_RS0108710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SIS domain-containing protein"
                     /protein_id="WP_028647968.1"
                     /transl_table=11
                     /translation="MSTLHFDRHVAEQPDTVRRLLTDPEVPALDPGRPIVFTGIGTSLH
                     AAQIAAGWVEALTHGRVRASAVNAHDLAVTSAVQPTDQVVVISHRGTKRYPNMVLRKAS
                     EVGAATVCITGVGQAEPEANLVLRTCPQEKASTHTVSHTAALTVLARLVGALLEDAASE
                     LIDALRDVPGQLERALAFRPSAAAVDALVRDEGVPALIAGTGTDAITAQEVALKLKEGT
                     YRWVEGMHTEFALHGTPAVFRPGMSAFLIAPSGEDGGRYEDLSGFLGKLGARVLRCADD
                     DHADLRFARTHPLMRPIVATLPFHLLVSEVAREVGSSPDLTHFEAEAWKAAFSQVTL"
ORIGIN
        1 ggtccgtggc ctggtgttcg tcgaggaggc ggtcgaagat tctcttggcg gtgtggcgct
       61 gtttgcgggg tgcgtccagg tcctggcgga ggatctcgtc gatgnagggc ttgtggacgt
      121 ccaggcgggt ggggcgcggc gggagcttct tgcggggttc gggccaggcc gagtccaggg
      181 cgctcttgac tgtgcggaag ccnacctggt gtttgcgctg ggcctcgcgg atcgacagtc
      241 ctgctctgat gtcgcgccgg atggcggcgt acagctcgac cttcgacggt ggcatcagcg
      301 ctccctcgtg gcggctacca cttcgatggt gccactgcaa gggcctgtgt gctgccagaa
      361 ctcatcgata catcgatgcg gtgttccggg gcgctgtcga gactgatcga caaacgctgt
      421 ccactctcac aaacaaagcc agtgctccgt gcacccgtca ggcaaccacc atcggactgc
      481 aaatcagatg ggcggcgcgg ggaggcgaca ccatgcaccc cgagtaggag acaaagaccg
      541 cctcaccgtg tcgtgcgccc cgcacagaga gctggaacgc acaccgaccc gtcctcctgt
      601 gtcctcctac catcgccgat gtagcggtcg ttaggacttc aagcagcccc atcctggacc
      661 gcttgtccgt gtggatctgg ttggcctcgg tcatcgtgcg cagagccgat gcgccaggcc
      721 cgtgtgagct ctgcgggtgg agggcggaca cagaagcggt cgaatcgggc gtcgattttc
      781 gcggggcgcc gtcagctcgc agtttccgcg cgtccagatc ggcgagttct ccccacgtgt
      841 tcgggagtcc ggttaggttg ggtttcggca gtcgccattg aacacaccat cttgaggaga
      901 gcgatcgtgg ctcagcgtcc gtcccctgtg cggggtatgc gcgatgtcct gcccgatgcc
      961 gcggagcggc gtcagtggtt ggagtccacg atccatcatg agttctcgcg gttcgggtac
     1021 cgccccatcg agacaccagc cctggaggac ctgaggttcc tggagtccgg gcagggcggg
     1081 gacaacgaga agctgatctt caagaccctg cgtcgtggta tctcgctgga cggggtcact
     1141 gacgtggctt cgttggcgga ctccggtctg cggttcgacc tgacggtgcc gttggcccgt
     1201 ttctacgcca ccaacgcccc cagcctgccc tctccgttcc gcgcggtgca gatcgggccg
     1261 gtctggcgcg ccgagcgccc ccagcggggc cggtatcggc agttcaccca gtgcgacatc
     1321 gacatcctgg gtgaggcgtc gctactggcg gagatcgaac tgctcagcgc gggcagtcgg
     1381 gctctggccg cggtggggtt ggcggagttc acagtccggc tcaaccaccg ccgtctgctc
     1441 accgggctgt tgaccgtgtg cgggtttgcg aacgagaccc acgcgaacgt gctgatcgtg
     1501 gtcgacaagc tcgacaagat cggtgtggag ggcgtcgagc gcgaactcgc cgaagcgggc
     1561 cacccccgtt cagcgatcac cactttgtcg gaggtcctgg ccaaagccga gtcagcgacc
     1621 gagcccgacc agctcgccca ggtgctgccc tcggggatgg acgaggaacc cttggaggag
     1681 ctgcgcacga tcgccgccgc cgtggtcctg cccgaggcgg cgcacaaggc acggctggtc
     1741 atggacctgt cgctggtgcg cgggatggga tactacaccg ggccgatctt cgaggtggcc
     1801 gcgcccggcc tgggctcctc gatcgccggt ggcggacggt acgacgagat gatcgggcgg
     1861 atcggcggcc gaccgacgtc ggcctgcggg ttcagcatcg gcttcgagcg tctggccgag
     1921 gtcctcgact ccgccgccgt gcggagggag agccgtgtgg cgctgctctg gcgctccgag
     1981 caggacctgg cgcaggtcac cacgcacgcg gatcggctgc gcgcagacgg gtacgtggtg
     2041 gagaccgtgc acgtcggcgg caagggcaag ggcgtgtaca agcggttggc cgccgccggg
     2101 ttcgacctgg tggcccaggc cctggacggg gccgagcctc gcccgctgtc ctcgtgaaca
     2161 ctgcacgacc ccggtggggt gacctccccg cggccgtacg ccggaaggtc acccgcttcc
     2221 tcggggagga ggtcgtcagc gaggaacccc aagacggcgg gtacaccccg gcgatggcgt
     2281 ctctgttgac cacctccagc ggccgtgccc tgttctgcaa ggcgatgccg gagaagcacc
     2341 ctctgtgcgc gaccttggcc gcggaggcgg ctgtggccgc gtcggctcct gcgggcgcgg
     2401 cccttcccgg cctcgtgtgg gaggggacgg aagacggatg gcgggtggtg gtgttcaccg
     2461 ccgtgcgcgg tcggcacgcg aacctctcac ctggttcgga cgacgtggcc gccgtggtct
     2521 cggcgcttga cggtctggct ggcgacctca caccctgccc gttcagcacg gcgcccaccg
     2581 cacgcgaggc gctctcaccg ctcctgagcg gatggtcgtc cctacaagaa caacctcccc
     2641 cggaactcga tccttgggca ttggccaatc tcgaacgtct ggccgcactg gaggagacgt
     2701 gggccgacca cgcgggcggg gacacgctca cccacggcga catccgcgct gaccagctcc
     2761 tcatcgacgt ccaggagagg gtgtgggtag tggactgggc gtacccctgc cgtggggcgg
     2821 cgtggatcga cgcggtggac ctcgtcacgc ccctgatcat gaacggccac acgcccgagg
     2881 ccgccgagaa gcaggtggcg ggttcggccc gcttcgccac ggctcccgct gccgctgtga
     2941 cttccttcgc cgtcgcggcg gccgggtact gggcgcgggt ctgtcggcag gctccaccgc
     3001 cggggccggg cggggtgagg ttgcgcgcgt tccaggccag ggcggccgat gccgccctgg
     3061 cctgggtgcg tcaccgtctc ggggagtgac tcaggcgagc acggggcgca gttcgtggag
     3121 gacgcgctgt tgggccaggt cgctgatgta agcgcgggcc gccgcaccga tcccgacccg
     3181 ggataggtcg cgcagcgcct gctccaccag gtcggccgcg gtgcgggcgg cggcctggat
     3241 ggcaccggtc gtggtgaagg ccaggcggat ctcctcgacc tgctcgtccg tggcgtggtc
     3301 tccctcgatc accggacgca gccggtggtc gtcaggcagg cgctggtgga gttcgaccag
     3361 gagcagcgtg cggcgcaggt ggcggatctc ggccgggtcg tccttgcccg cctccatcag
     3421 gtccgggcat ccggtggcca ggtcgtccac gatctgcgag gcggcgccga tggtctccag
     3481 aatccgggcg acggcctcgc gttgggcggg gtctgcgccg gtggcggtgt ggccgatgcg
     3541 ccaggggagg ccgtagcagt agtcgcctgc cttgtcctgg tacatgcgca cgatggcgtc
     3601 cgtggtgatg gactccaggt cccgctgcca gagcagttcc tggagttggc cgtgttgggt
     3661 ccggcggacg cactccacga ccacgtccca caggggtgct cggtgctgcg ggtcggcgtc
     3721 gttcagcagg ttccgggcga gggagaggag taggtctgcc cagaacaggg cagctccgtt
     3781 cccggcggtg ccgatgcggc gtcggaacgc ctcgggcagg gtggggtggc cgaacttctc
     3841 ggtgtcgccg tcgacgatgt cgtcgtggat ggcgaacagg tctctgacca cctgcgggac
     3901 cagggcgacg gtgccgagcc gttcgaccag gtcatcgggg agttcggtgt ggtcgtgggc
     3961 cgagccgacc agcgttagga cggggcgggg caggagggag tcgacctggg cgtaggccag
     4021 gtagtcctgt cccagtccgg ccaggtgcgg gggcaggttc tgtgtccagt gggtgagggt
     4081 ccgcgtccac agggcaccca ggggcgggga gaagcggtcg agtgtggtgg tcagcacgag
     4141 gtggtctccg ggatctgtcg ggcctgggcg tagcggccga tggcgtcggt gtcggtggcc
     4201 tcccccaccc acagatcgac gcgtcggccg tcgatgtggt cggaggtagt ggcgtaggcg
     4261 cgcagatagt cacggaccgg atcgccggtc ggtttcggga cgaggagccg gtcggcggtg
     4321 ctgtgaccga agtggtgggc tcgctggtgg ttgggggtgt cggtgaaggt tccgcaggcg
     4381 tccatgacgg ccaggaggcg ttcgatcccg aaggcgaagc cgctcgcggg aacggttccg
     4441 ggcccgttgg cggcgaagtg gccaatgagg tggtcgtagc ggcctccgcc ggcgatctcc
     4501 acgaagctgc cgcccggtag gacgacgtcg acctcgaagg ccaggccggt gtagtactcg
     4561 tggctgcgca ccacgcccag gtccaccgcc acgttcaggc ccgcctgccg tagggcctgg
     4621 gccgtcgatg agagtcgctc cagatggccc ggggccacgt cgcccagtgc ggccaggagg
     4681 ccggggtcga cgtcgccgga gacgtggtgg gccatcgccc gccagcgctc caccgtctcg
     4741 gcggggtggt ccgcgagcag ggcgtccaga cgtgtgtcga ggccggaggt gcggtccggg
     4801 tccttgcccg ctcggcactc cgcgagggcg tcgaggcact ccttgaccgc gaccgtggtg
     4861 gtttcgtcga agccgctgcg ctcggccagg gcgcggaaga cgccgacgtc gctgatccga
     4921 acgcgtaccg cgttcccggg ggtgccaagc gagcggagtg cgccgacgat gaaggtgatg
     4981 atctcggcgt cggccgccgc ggacgcgact ccgaggatct cgacgccgaa ctggcggaac
     5041 tcgcgcgcct tgcccgggga gagggtgtcg accgcttcgt tgcgccagca cggcaggtca
     5101 tagaagacct tcagcggcag ggtctgggtg ggcaggaccg aggcgagcca gcgggcgacg
     5161 gagaccgtgc cctcggggat cagcacggcg ggggtgttct ggtgggtgtg ggtatggccg
     5221 ggcccgtagt cggggacgtc gagctcgaag acgcccttgg ggttccactc gggccacggc
     5281 gaggcgccga cgacctggcg gctgaaggac gccttgcgtt ccagggcggg gacttcgaga
     5341 cggtcgtatc cgcgggtgtg ggcgtactgg gccaggacgg actgggtgta gtcgcgctgg
     5401 cgcagctcgg ggccgaaccg gtcacgggtt cccacgaagg gctgggtgtt gcgaggggtg
     5461 tggggcacag ggggctccgt tcgtcgaggt gtcgttgtcg gttgtcgtgt ggtcgtggag
     5521 ggggcgcggc ggcacgggtg ggctgggggt tgtgccgccg cgccggttcg tcggcgctga
     5581 cggtgtctcg cccggttggg cggtggtctc gtcgaaggga cgtgtgctca gttggcgggt
     5641 gtgaggcgtt cggtccacag ggcgtcgacc tcactcctga gatagcggcg gtggccgccc
     5701 ggggcgcgga agctggagat ccgtccctcc ttggcccagc gcgtcacggt ctggctgtcc
     5761 acacggaaga gggcggcgac ctcggcgggg atgagggcct ccagggacgc tgaggtgttg
     5821 tcgctgttca ggggtgtcat cgggccggtt cctctcgtat gtgggtggtg ggctgcagcg
     5881 gggccaggtg cgcgcgccag tcgtccacct gggggttgcg caggcgcagt gctcggcgtt
     5941 cgcgggcggt catgccgccc cacaggccgg agtcgatccg cagttccagg gcttcggcca
     6001 ggcacgccgt gcgtatgggg cagggagcgc agatgtgtcg ggcgcggtgt tgctgaaggg
     6061 tgttgccgaa caggcggtcg gggtcgggca ggtcgcggca gaaggcgcgg gagtcggtga
     6121 ggggtgtgct catgtcggcg gccgtgtgaa gtggtggtgg gcgggtgtgc agggagttcg
     6181 ggagcatgcg ggttccggac gggaacggtc agcgggcgcc gtcgtggcga ggtccgtctc
     6241 gacgtgcagg atctgtcggt gcagttcctg accggtggac gcgaacagcg gagcaacggg
     6301 ggcgctgccc cggtagaagg cgaagaaggc gcgcgagccc gggccccaca tcacgagcca
     6361 acggctccgg cgacgcagtt ggagctggcg ggcggccatg tactggtcgt ggtcgtccct
     6421 gacgttccag gccaccgtga tcaccactcg gtatggtcgg cgggccgggc aaggttgcgg
     6481 tcgatgcggt ccacctcgaa ccagacgctg gtacgaccgt cgtcgtggtg gatagtgccc
     6541 caccggctcg cgcccgtcgc gaccaggtgc agtccgcgcc cgctctcgtc gtcggggtcg
     6601 aggggccgca ggtggggcac ggtgatctcc ccgtcgcggg ggccggcgtc ggtgatgcgc
     6661 acctgggtcc ggcccgccag tttgaagacg ctgatggtga tctcgccgcc cggatcgccc
     6721 gatcgggtgt ggcggatgca gttgttgaac agttccgagg cgagcagttc gatcgggcgg
     6781 agctcccagt cggggagaga cgccagtgtc cgcaggcgac ggcgcatgat cttggcgtag
     6841 gcgggttcac cagggacggt catcgcggag cccgtgaact cgtcgtgggg ctccagcagg
     6901 accggggcgc ggtccgaagg tgcggtggcg cgcttgggca gcgggggaac ttctcggttt
     6961 ccggtgtcgg tctccgtgtt cttcgcctgt tccaccagtg cggccatgtc ccatcaccgt
     7021 cctctcgtac ctggtcaccg tgccttgtgc ggcagttcca ggtcgttgac gagttctcat
     7081 tcttgggttg gcgcgccttc ggttcccatg agcaggggtg atgatcgtta ttacggtggt
     7141 gatgcttttg ggagcagggc tggcgaggca ggtgaggagc ccggtttcat gggtggaaca
     7201 tttcctcctt caagggatcc gtggtggcga tatgcgcgaa ttgcggcagg gagagggcac
     7261 ctgtcgctga tgtgaagaaa aggtgtttgt gtatacccaa ggggttctgg gagatacctg
     7321 aggcgcagga ggctgctgga cacctcgacg cgggctcgct ggtacgtctt ctgcgttcgc
     7381 gcacgaacct gtcccaggag gctctcggcc ggttgaccgg gctgtcccag tcgatggtgt
     7441 cccagctcga atcgcacaag cgcgagttga aggacgtcgt gaagctgcgc cgtttcctcg
     7501 acggactcgg ggcgcctcgg gtgacggcca ctcgcacgca gcgggagagc atcgagagca
     7561 cccggctgtt ggcgcacgcc gcccaggtca ccatgggcgc ggcggagatc gatccccaca
     7621 ggtggcgtgg cccgaacatg cccgaggcgg ccctgcccgt ccggagggtg acgggaaccg
     7681 acgtggacca cgtcgagacg gtcaccaagg cgctgcgggc cgctgactac cggctcggcg
     7741 gtggtgcgtg cctggacgcg atcatggcgc acctggccta cgcccaccgg ctgctgcgcg
     7801 cggccaaacc cgggaaccag gtcggccttc agctctaccg ggccgtcgcc gatctgcaca
     7861 acctcgccgg gtgggcgagt ttcgacgtcg gccgttacaa ggtcgcggcc gagcatctgt
     7921 ccctggcgct ggagcaggcc cgatacatcg aggaaccctc gctggtggcc aatgtgctct
     7981 accgtatggg gcgcctgcac ctgcaccgcg gccacaccct ccaggccctg cggttcctgc
     8041 aactggggca gatcgccgcc caggactccg ggtgcgagcg caccgtcgcg ctcatgtgcg
     8101 ccaacgctgc ctgggcctac gccgtcctcg atgaccacaa gcgctcgatg gactccctcg
     8161 cccgcgccca cgacgccttc gcgcgcgccg atgcggacac caccccgtgg gtgcggttct
     8221 tccgcgaagc cgacctggac gccatgtccg gggtcgtcaa cgccgcactc cccacaccct
     8281 cgctcggtgc gcgtcatcga ccagctcgcc ccactccagc aagccgctct ggcctaccgg
     8341 ccccggggcg agaccgccga actcgccgcc gagattgcta ctcttcgcac atcatgagca
     8401 ccactcccgc tccctccacc agcccccgct tcgccctcac ccgcgaccgc gtccacgacg
     8461 ttctcgcggc cctgtgcgag gaggccgggc tgggagccaa ggccgctggt gacgccgagc
     8521 tgatcaagtt caccaacaac gccgtctacc gcctcccccg tgtggggttg gtggtgcgca
     8581 tcgccggatc ggcgaccgtg gccgaacgcg tccccgtcgt catccaagcg gcccggtggc
     8641 tcgcccagca cgacgctccg acggtgcggt tggtcgagga tatcccccag ctggtgcggg
     8701 tcggtggggc gacagcgact ttctggcacc tggtgccctc caccggcccc gaaccgacag
     8761 ggaccgatct gggccgcatc ctccggcgcc tccatgccct gcccgccccg ggtttcgcgc
     8821 tgccgtcgtg ggagccgttc gcgcgcatcc gcagccgcat cgcggacgcc gaagggctgg
     8881 ccgaggccga tcgggtcttc ctcaccgagc gcaccgacca cctggagctc ctggtccagg
     8941 acctggagtt cgaactcccc gccggggtgc ttcacggcga cccgttcatg ggcaacctca
     9001 tccccggccc taacggcccg gtgatctgcg acttcgacag cctcagccac ggccctcgcg
     9061 aatgggacct gatccccgcg gccgtcggca aggtccgcat ggattacccc accgaccacc
     9121 acagcccgct cgcggccgag tacgggttcg acgtcctcac ttggcccggg tttcctgtcc
     9181 tgcgccagct ccgcgagctc aggctcgtca ccagcgtcct gccggtcctg aacaccaacc
     9241 ccggcctccg cacccagtgg cgccaccgcc tcgacaccct ccagcgcagc gacaccacca
     9301 cccgctggtc cacctacagg tagacacgca ccaggtgacg ggaggcgatc ccggcacacg
     9361 ccacagcctc cagcagaccc agtgcaagac acctgtctct gaacaccgtc aagcgctacg
     9421 cgcgcgttcc cgaacccgac cggctgcgcc gtgcccgtgc agcacctctt cggcgggatt
     9481 cgccagctcg gctaccaggg aagcctcaac ctgctctagc ctgctcgaca gcgaccggga
     9541 gtcggtcccg cccaaggcct tcggcaagct tctcctggcc cgccccgaac ggctcacacc
     9601 cgaagagggc cagactctca ccgagctgac cgaggcatgc ccggagataa cgcggctggc
     9661 cgaccacatc ggcggcttca cccggctcct ggaacccgcc ccgggcaacg ccgaggacct
     9721 gaccgcgtgg atcgccgacg ttcgtgagga cgatcctccc cgcctgcacg ccttcacccg
     9781 cggacttgac cacgaccggg ccgcggtcga cgcggtggaa ccgcccgaac ccgaggaccg
     9841 tcacgtcctc gcggccgccg tccgggaacg gtcacggatg tgcttacccg gcctcaacgg
     9901 gatggcccgc accgcgatgc gagcgggccg gcggttccgg gcccagaatc cctgagatcc
     9961 ggcagacccg tgaccgctga gtggccggaa ccggtcactg cgcctttcca tgtgccgcag
    10021 ccgaggagtc cgtcgatgcc gacggccgac atgccgctgt gccgaaccgg cactgttgat
    10081 ctcggtgcag gccacggctg tcaccttggg attcggttcc attccagccg accgatagcc
    10141 cggcggcggt cgttcgcgtg caaggaaaac ggtcaggcca gccgcccggc agaaagtctc
    10201 ccatacccac aaaaacaccc caaagggtgc aaaacggaag tctgatttgg gcgtggatct
    10261 catattttgg acacatgaaa gatgcgttgc ccgagttcgt gcggtataca tctatgccga
    10321 gaacgattta cccggccacg cagagccttc cgtcaaaggc gacagtcgga cacctgcaga
    10381 catcccgcct cccatttcag gagcttctgc acatgaccac cccttcgttg ggctgcccta
    10441 ggccatcggg aacagcgtac tcctctatcg acgccacatt gagtcagttt tccgagtacc
    10501 gtgactttcg atctggagcc ctggatcgcg ctgtttacag caaattgatc gagcagagct
    10561 ccgatgagct actcgaggcc ggcctcaaca gagaccagat gaatctatcg actcgcttcc
    10621 ctctcgacga tctcgcgttc gtcaaagaga cgatcacctc gcttcgccag cagtcggtcc
    10681 tacccgacag agacttctcc acttcgggat attcggactg ggagcgcctg gtcgcatcat
    10741 tgtacgacca cggcgggaac atgacctata tatttccgga ggaggcgctg ttgatccacg
    10801 ccctcgcctc ggtcatcaag cctcggcatg cggttttcgc tggttcctac tacggattct
    10861 gggcgatctg ggcggtgcgg gaggtcgtcg ccgcaggcgg tgaggtcacc ctgatcgaca
    10921 cggatgacac cgtcatgcac ctggcccaac ggaacttcga acgcctgggc gtgtcagaaa
    10981 acgtcaactt cgtcgtggcg gatgcgatct cctactcgcg ggcggagctc gccgacatcg
    11041 acttcgttgc gctcgacgcg gaggggccga agtcctgcgc ggatgaggac ctgcgggaca
    11101 aggcgatcta ctatcccatc acgcaagcga tagccccggc gatgcttcct ggggcgattc
    11161 ttctggccca caatgtccta ctggagaacg tgacgcagaa cgcgtacttc gaggagcgca
    11221 tcgcctacaa cgagctccag tacgcgcgct ggcacagttt tctctcagag caattcgact
    11281 tccgtatatc ctatccatcc acagaagggg tggggatcta ccggaaggct cgatgatgtg
    11341 cggatccaca gggttagccg tcggctgtca agcgcagttc tcgtgtccca aagagctgtt
    11401 ccgcacagga gcctcagaag agccgcagaa cgactatcgc agtccgttcc gggactggca
    11461 tgagcgcgcc agtgttcgca aggaaccccg ccgagtcctt tccccgtcgg acgaccgata
    11521 cctcctgttt gatgccgacc tcgttcccac gagctcccac atcctggtcc aagagcttcc
    11581 cgatcctcag cggaacgagg tgctgacgca gcacctgtac cgctacctaa agttcaccac
    11641 gcagttggag cagctggtgg tgaacaagac gatgctggac atcgcctatg gccgtatcgg
    11701 cgtcgacctc ccccgcggaa tggtgttcga cgcgcacaag atctactgtg acgaggccta
    11761 ccacgccctc ttctcaatgg atatgtaccg ccaggtcatc gatgccaccg gcgtggcacc
    11821 ccgcatcggc tccgaccccc atttcttccg cagactgcga cgtctactcg aggacgtcga
    11881 cccgtcgatg aggctcctgg tggaactgct attcgtgttc tgctccgaga ccctcatatc
    11941 cgggactctg gacagcgggc gcgatcagca ggtggacccg gcggttcacg agatggtcaa
    12001 agaccatgcg aaggacgagg gaaagcacca cgcctacttc gcatcgttcc tcttccatct
    12061 gtgtccccag atccatacca agtaccagga atcagccgca gcgctgatcc cggacctgat
    12121 catgacattc ctagagccgg acagggaatc gctggtaagt gaactgtgcg gatacgacct
    12181 aagccaggac gaggccgagc aggtcgtcgc ggagacgttc accagagatg tcgtcagaga
    12241 catacgcgcg ggcgaccgcg cgtcacacac tcagatactg ccgtgaagcc ggagtgctcg
    12301 accatcccgc ggcagtagag cgatttcacg agcttggatt gatcgaggag gatcaatgac
    12361 cggcgcctat gcaatccgcc ccgcagaaat ctcggacctg gaagggatcc gggagattct
    12421 gaaccatttt atccgcacga gtgacgcgac cctggactac gacgaaaagt ccgaagccga
    12481 catggagtcc tggtataagt cccataacga ccgctatccc gtctacgtct gccatgaaga
    12541 atccgggcgt gttgtcggtt acgcgtccct cagcccgttc gccgctcggg ccggttacca
    12601 ggcgagcgcg gagatctcgg tctacgtccg ggaggaggcc cagtcccggg gaaccggaat
    12661 cgccttgtgc gaacggatga cctcgctggg gatggagacc ggtttcaccg cgatcaccgc
    12721 gatcatgaca tcgacgaaca agccgtccat ccgcatggtc gagatcctcg gttaccagcg
    12781 caccgggagc cttcggaaca tcggtgcgaa attcggacgg cctgtctcct tggagatcta
    12841 ccagatctac ccccagtagg agctcttgag tggttctccc gcaggcgcga ggaccacgaa
    12901 cggtcaacga tgcgacacaa ctgcatcgaa cggagcattt tcctgcacgc gcacagagga
    12961 gacacgatga gtaccctgca tttcgaccgc catgtcgccg aacaacccga caccgtacga
    13021 cggctactca ccgatcctga ggtcccggcg ttggatccgg gacgaccgat cgtcttcaca
    13081 ggtatcggaa cctcgctgca cgcggcgcag atcgccgccg gatgggtgga ggcccttacc
    13141 cacggccgtg ttcgggcgtc ggcggtcaac gcccacgacc tggccgtgac cagtgcggtg
    13201 cagccgaccg accaggtcgt ggtgatcagt catcggggga cgaagcgcta cccgaacatg
    13261 gtgctgcgca aggcctccga ggtcggagcc gcgacggtgt gcatcaccgg ggtcggccag
    13321 gccgaacccg aggcgaacct ggtgctgcgg acctgtcccc aggaaaaggc gagtacgcac
    13381 acggtttccc acactgccgc gctgacggtt ctcgcccgac tcgtcggcgc cctcctcgag
    13441 gatgccgcgt ccgaactcat cgacgcgctg agggatgtcc ccgggcaact ggagcgcgcg
    13501 ctcgcattcc gcccgtccgc cgcagcggtg gatgcactgg tccgcgacga aggggttccc
    13561 gcactcatcg cgggcacggg aacggacgcc atcacggcac aggaggtcgc gctcaagctg
    13621 aaggagggca cctatcggtg ggtcgaagga atgcacaccg agttcgcgct ccacggcacc
    13681 ccagcggtgt tccggcccgg aatgtcggcc ttcctcatcg ccccgtccgg ggaagacggg
    13741 ggaagatacg aggatctctc cggctttctg ggaaaactcg gtgcccgggt cctgcgctgc
    13801 gccgacgatg accatgcgga cctccggttt gcccggacac accctctgat gcggccgatc
    13861 gtcgccacgc tccccttcca cctgctggtg tcggaggtcg cccgtgaggt cgggtccagt
    13921 cccgacctga cccatttcga ggccgaggcc tggaaagccg cgttctcgca ggtgaccctg
    13981 tgagcggggc cccgtccacc ggcgacgcgg tgacccgcgc gtacttcgag gcctgtgaaa
    14041 cgggtgatct ggcggaggcc gtctggaagg cccccttccc ccggtcgttc cgtgaccttt
    14101 ggtgggaccg cctgctggcc cgcccgctgt tcatccc
//
