LOCUS       NZ_KI911320            20288 bp    DNA     linear   CON 04-JUN-2024
DEFINITION  Mesorhizobium sp. WSM1293 MesloDRAFT_scaffold_4.5, whole genome
            shotgun sequence.
ACCESSION   NZ_KI911320
VERSION     NZ_KI911320.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Mesorhizobium sp. WSM1293
  ORGANISM  Mesorhizobium sp. WSM1293
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Phyllobacteriaceae; Mesorhizobium.
REFERENCE   1  (bases 1 to 407418)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly                          :: ALLPATHS v. R37654
            country                           :: Greece
            environment :: Host; Plant root; Root nodule; Soil
            investigation_type                :: bacteria_archaea
            lat_lon                           :: 37.147182 24.514618
            project_name                      :: Mesorhizobium loti WSM1293
            sequencing_meth                   :: WGS
            biotic_relationship               :: Symbiotic
            rel_to_oxygen                     :: Aerobe
            finishing_strategy                :: Level 1: Standard Draft
            GOLD Stamp ID                     :: Gi08882
            Current Finishing Status          :: Level 1: Standard Draft
            Type Strain                       :: No
            Funding Program                   :: DOE-DD 2010
            Isolation Site :: Serifos, towards Hora from beach
            Host Name                         :: Lotus sp.
            Cell Shape                        :: Rod-shaped
            Motility                          :: Motile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28
            pH                                :: 5-8
            Gram Staining                     :: Gram-
            Symbiotic Relationship            :: Mutualistic
            Diseases                          :: None
            Phenotypes                        :: Non-Pathogen
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method                   :: ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: 454-GS-FLX-Titanium; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000513875.1-RS_2024_06_04
            Annotation Date                   :: 06/04/2024 01:41:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,732
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,524
            CDSs (with protein)               :: 6,524
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 76 of 144
            Pseudo Genes (incomplete)         :: 111 of 144
            Pseudo Genes (internal stop)      :: 9 of 144
            Pseudo Genes (multiple problems)  :: 45 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:13:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 352501
            Orig. end                         :: 372789
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KI911320.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 404574
            Source DNA and Organism available from Wayne Reeve
            (W.Reeve@murdoch.edu.au)
            Contacts: Nikos Kyrpides (NCKyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20288
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20288
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20288
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10288](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10288
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            899..1795
                     /locus_tag="M729_RS0134295"
     CDS             899..1795
                     /EC_number="2.7.7.9"
                     /GO_function="GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006205242.1"
                     /locus_tag="M729_RS0134295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UTP--glucose-1-phosphate uridylyltransferase"
                     /protein_id="WP_013528099.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.7e-08, bitscore:
                     27.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIRKAVIPVAGLGTRFLPATKSMPKEMLPVVDRPVVQYAVDEA
                     FEAGIEHIVFVTGRNKAVIEDYFDLHPELIGTLEQTGKKTQLEALESMLPVAGATSFIR
                     QQSPQGLGHAVWCAREVIGNEPFALLLPDMVSFGGRGCLAETVELYERTGGNVIAVERC
                     EPSETNKYGIVGRGAEIGGGFEVTAMVEKPAPANAPSNFYINGRYILQPEIFALLGNQQ
                     RGAGNEIQLTDAMVRLSKDQPFFAQPFLGRMFDCGSKEGFIQANIAFALARDDMKGPVF
                     EMLQEFVRSHERQEEAA"
     misc_feature    1860..1873
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            2031..4418
                     /locus_tag="M729_RS0134300"
     CDS             2031..4418
                     /EC_number="2.7.10.2"
                     /GO_process="GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216: exopolysaccharide biosynthesis domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010913094.1"
                     /locus_tag="M729_RS0134300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="WP_027164272.1"
                     /transl_table=11
                     /translation="MNYANFPLDKRMPLPNSDAGDGEDFIDIERLLGMAARQAKVVAVC
                     AVIGLFLGLLYLQTTPPKYQSIASVLIDEGLNKIVDDISATSTTMQTDSAILSQIEILT
                     STRLAAVVVDKLKLDQNDTFMNPPQSALAQGIGLIRSLIQYVRPSSSMPGGADFSKLDP
                     AARDALIATSRRDYAILKLQNEIRAERVGRSYVIALGYQATDPALANAITKAYADAYLA
                     DQLDASFDATERAAVWLQGRLTELRQSSQAASLAVEKFRAEHGLAANSDGQLMSDKQLS
                     DLNAQLIVAQADTARASARYQQYKAIVDSGSENAFKDAAISSDQPSSSVISALKTRYLT
                     VAKRLQDVEANFGPEHPQAVALSKEKADISTQIFGELKQLTESYRNEYEVAQARETALR
                     ANVAAAQGKSSVDNQTQVKLRELDQQATALTTLYQTFLGRYEEAAQQQSFPVGKIRIIS
                     DASMPMTASSPRTIVVLGLSLVLGLLMGAGFGGLNEFNERFFRTGEDVRDRVNLKFLGY
                     LPTIGGKLGKEEKPGETQVDAKTTQSLSSAEKRARMRVSIDSPASMFSETLRSAKIAFD
                     VVMEGQGSRVIGIISVLPGEGKSTVAANLAGLLAANGSKTLLIDGDLRNPGLSRGLGME
                     TEQGLMEAVVGGQTWQSVGKIDRQTKLAIIPAVLRGHFSHTSELLSSAGMRRFIENAKE
                     TFEYIVVDLPPLGPVVDAKAFAPLVDGFVLVTEWGRTPRAMVRSMLESEPYVANKIVGA
                     VLNKVDLKKLAKYGSFGGSEKFFDKYSSYYLEKSEVRGKAPV"
     gene            complement(4495..5253)
                     /locus_tag="M729_RS0134305"
     CDS             complement(4495..5253)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006206924.1"
                     /locus_tag="M729_RS0134305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_013528097.1"
                     /transl_table=11
                     /translation="MTLFQRKPRIAARPRLDIDMQDAVVYAIGDVHGCYKELRALEQKI
                     LLDSLRFQSRKIIVMLGDYIDRGFQSARVLDHLLAPPPKGFQRICLAGNHEVAMLNYLD
                     GNLSREPWLATGGLQTLFSYGIDPARLTSLYGSSAQIDRRIREIIPDDHVSFLRGLPIM
                     VRSRKFVFVHAGIRPGVDLAAQTDHDLINIRSDFFEATHLLDRWVVHGHTPVDVPKLEG
                     RRLGIDTAAFQSGRLTAVRIADKQGRLIFS"
     gene            complement(5500..6582)
                     /locus_tag="M729_RS0134310"
     CDS             complement(5500..6582)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019862857.1"
                     /locus_tag="M729_RS0134310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyltransferase"
                     /protein_id="WP_024501824.1"
                     /transl_table=11
                     /translation="MAQQKITFGGVDILRFLAAVMVMVYHYGFWVWAYPDGVSARATGG
                     VPPQPAIGAWVESGWVGVQIFFVISGFVIAFSAERSTPLRFFEARVKRLAPAVWICAPV
                     TAAVLLIVGLSWPTDAVVRLVRTGLFAPYAPWVDSVYWTLGIEIAFYAVVWTLLRLGRF
                     HLMEIVALAIGLVSALFWCLYYPLDWADLAETRTLDLLLVHHGVFFATGVMLWLMRFKA
                     VTAARLAFCALFLAGGVLQIASSVDVHILKVGRDMPFAPPILIFLIGIALMAWSLRLDL
                     SWSGWRRIGLMTYPLYLLHDVVGAALLGILVRAGLPHLFSMAVVGATMIAASWLVATEA
                     EPRIRLLLDHTVFRYRLKAA"
     gene            complement(6696..8603)
                     /locus_tag="M729_RS0134315"
     CDS             complement(6696..8603)
                     /NRPS_PKS="Domain: AMP-binding (62-506). E-value: 1.2e-88.
                     Score: 289.4. Matches aSDomain:
                     nrpspksdomains_M729_RS0134315_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015314207.1"
                     /locus_tag="M729_RS0134315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="propionyl-CoA synthetase"
                     /protein_id="WP_027164273.1"
                     /sec_met_domain="AMP-binding (E-value: 7.2e-99, bitscore:
                     325.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASRYHEVYEGWKRDPEQFWADAAGAIDWYSPWDKVFDANAGVYG
                     RWFTGATCNTCYNAIDRHVAGGRADQIALIHDSAIAGTVKKFTYAELKREVVALTSVLK
                     NRGIGKGDRVIIYMPMVAEAAIAMLACARIGAVHSVVFGGFASHELATRIDDARPKLII
                     SASCGLEPGRVVAYKPLLDKAIEISRHKPDACLILQRDQLRCELKEHFDIDYADAVARE
                     RAAGANVDCVPVLATDPLYIIYTSGTTGQPKGIVRDNGGHMVALKWTMENEFGVKPGEV
                     FWAASDVGWVVGHSYIVYGPLLHGCTSILFEGKPVGTPDAGTYWRVIAEHGVVALFTAP
                     TAFRAIKGQDPKGEFIAKHDLSKFRTLFLAGERADPETIKWAEQKLNVPVVDHWWQTET
                     GSPMTINPAGLGLLPVKYGSPGVPMPGYDIRVLDDAGHEVQRGTLGNVVIKLPLPAGCL
                     PTLWNADQRFRQAYLDEFPGFYKTADAGMVDEDGYLYVMARTDDIINVAGHRLSTGAME
                     EVLSAHPDVAECAVIGIADAMKGQVPLGFVVLNAGVTRDIGSIENEVVGLVRERIGPVA
                     AFKTVVTIKRLPKTRSGKILRGTMQKIADKEEWAMPATIDDPVILDEITAALKERGIGL
                     "
     aSDomain        complement(7086..8417)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M729_RS0134315_AMP-binding.1"
                     /evalue="1.20E-88"
                     /label="M729_RS0134315_AMP-binding.1"
                     /locus_tag="M729_RS0134315"
                     /protein_end="506"
                     /protein_start="62"
                     /score="289.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HVAGGRADQIALIHDSAIAGTVKKFTYAELKREVVALTSVLKNRG
                     IGKGDRVIIYMPMVAEAAIAMLACARIGAVHSVVFGGFASHELATRIDDARPKLIISAS
                     CGLEPGRVVAYKPLLDKAIEISRHKPDACLILQRDQLRCELKEHFDIDYADAVARERAA
                     GANVDCVPVLATDPLYIIYTSGTTGQPKGIVRDNGGHMVALKWTMENEFGVKPGEVFWA
                     ASDVGWVVGHSYIVYGPLLHGCTSILFEGKPVGTPDAGTYWRVIAEHGVVALFTAPTAF
                     RAIKGQDPKGEFIAKHDLSKFRTLFLAGERADPETIKWAEQKLNVPVVDHWWQTETGSP
                     MTINPAGLGLLPVKYGSPGVPMPGYDIRVLDDAGHEVQRGTLGNVVIKLPLPAGCLPTL
                     WNADQRFRQAYLDEFPGFYKTADAGMVDEDGYLYVMARTDDIINV"
     CDS_motif       complement(7836..7883)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M729_RS0134315_0001"
                     /evalue="1.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="M729_RS0134315"
                     /protein_end="256"
                     /protein_start="240"
                     /score="24.1"
                     /tool="antismash"
                     /translation="YIIYTSGTTGQPKGIV"
     gene            8747..9559
                     /locus_tag="M729_RS0134320"
     CDS             8747..9559
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528094.1"
                     /locus_tag="M729_RS0134320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2259 domain-containing protein"
                     /protein_id="WP_224618434.1"
                     /transl_table=11
                     /translation="MSAAVRIIGRFSLSSVMGAVLAMSTGTAEAGDAAARHIIGFSPDG
                     AYFAFEQYGTLDAGASDSGWSEIDIIDTRTDRFVGGKPILVVDETEEATLTLEQARAQA
                     AAQAAPILAHYAITSPAEQTASDKFTFPGEMVAYNDISRLEQVSQKWLSPLHGETGVST
                     IQLDEILAASTGDCSASFATTERRDTSGKALGFRLTLQGQDGKPVKILHEDKTVPGSRN
                     CPTSYSLSESYELTPAGKLPVIVVLVQRFSQGFEGRDRRFLAVTGQPR"
     gene            10001..10288
                     /locus_tag="M729_RS0134330"
     CDS             10001..10288
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872463.1"
                     /locus_tag="M729_RS0134330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_027164275.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.5e-14,
                     bitscore: 47.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.1e-11, bitscore: 39.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-08, bitscore:
                     29.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEIVSGTVLRLAEDASVQHVGDGAVVLLARSGQLYTCNGTTEAF
                     LDKVDGARNLDQIVDLLCEEFEVDKGTLDQDMAALATDLISEGILAALGA"
     aSDomain        10022..10270
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M729_RS0134330_Stand_Alone_Lasso_RRE.
                     1"
                     /evalue="2.60E-15"
                     /identifier="RREFam002.1"
                     /label="M729_RS0134330"
                     /locus_tag="M729_RS0134330"
                     /protein_end="90"
                     /protein_start="7"
                     /score="47.2"
                     /tool="antismash"
                     /translation="TVLRLAEDASVQHVGDGAVVLLARSGQLYTCNGTTEAFLDKVDGA
                     RNLDQIVDLLCEEFEVDKGTLDQDMAALATDLISEGIL"
     aSDomain        10076..10270
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M729_RS0134330_PqqD_RRE.1"
                     /evalue="8.60E-10"
                     /identifier="RREFam006.1"
                     /label="M729_RS0134330"
                     /locus_tag="M729_RS0134330"
                     /protein_end="90"
                     /protein_start="25"
                     /score="29.2"
                     /tool="antismash"
                     /translation="VVLLARSGQLYTCNGTTEAFLDKVDGARNLDQIVDLLCEEFEVDK
                     GTLDQDMAALATDLISEGIL"
     gene            10288..10722
                     /locus_tag="M729_RS0134335"
     CDS             10288..10722
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF13471"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528092.1"
                     /locus_tag="M729_RS0134335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_024501821.1"
                     /sec_met_domain="PF13471 (E-value: 1.2e-13, bitscore: 45.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADGPLLRALFRCHLWASARLMPVLVTNRSFEEVLRWAPLASSTP
                     YRGLPSAYIVASVNRTVRHPWLMRDRRCLREGLLGHRFLRLAGFDPDLRFGVEPQSMQA
                     QRLSAHCWVCLDGKPVVSDKLPGMVEIYRHHADAVKARPA"
     gene            10809..11696
                     /locus_tag="M729_RS0134340"
     CDS             10809..11696
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528091.1"
                     /locus_tag="M729_RS0134340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine kinase"
                     /protein_id="WP_245267689.1"
                     /transl_table=11
                     /translation="MLGSLRIEEPVAPDFRLEITETDTLDETPNGSLVFDGEVPEDGPC
                     RMIEDGGIVHLVFPGRQTVAINGGEGWAELRISTGTKAAWTPSMLVLDAALDAGGQHML
                     HTAGLTLPDRDAVVLVHAPSGTGKTTTSLALATQGFGLCSDDAMILNVASGKVVAWGLP
                     RAVKIHRKAAEMIPQVAPCLGQTWDRNGEQPVSLERLGGIIRVENASARPVAALLHLAR
                     SADGQTRLVAMARTDAMVALAVDNVRTGMTGLLPMQKRRLATIAGLVNAVPTFQLEVGG
                     RPADAAALIRATLD"
     gene            complement(11704..12720)
                     /locus_tag="M729_RS0134345"
     CDS             complement(11704..12720)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013891464.1"
                     /locus_tag="M729_RS0134345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_032809903.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.4e-23, bitscore:
                     78.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPPLTSAEERLLLRFADPEAAAGGEDLSAKTLTALLDNAEFHGV
                     LPIMLRKLSGDARLPADADLHGKLEDLRQKATIATGQSMLLKYHGDRIMKGLAADNIPA
                     RIVKGPVFARKLYRNVADRPFTDIDILVEPANLARANQVIAACSFELGSNEAESYELQE
                     FKWLEKENSSLLVELHGDLVHDTGMRRRLSLGFPELRAIDGEATDTPAALLTIAIVHAA
                     GGHKFHRLQLCVDVLQGVRALQSPEAEARLFDAARMTGIELELAIVLNVTGQLFDESRA
                     LELAGRIKPDLSIRLARRLITTNTLLGVNSRDRLGSRLRRDAFRWIQRLAKARPQVA"
     misc_feature    12771..12788
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.23"
                     /tool="antismash"
     gene            complement(12785..13771)
                     /gene="dhaK"
                     /locus_tag="M729_RS0134350"
     CDS             complement(12785..13771)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0004371 - glycerone kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006325220.1"
                     /locus_tag="M729_RS0134350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="WP_027164278.1"
                     /transl_table=11
                     /translation="MKKFINSVDTVLTESLDGFVAAHADILVLGDEHKFIRRKTLRPGK
                     VALISGGGSGHEPLHGGFVGHGMLDAACPGQVFTSPTPDQMLAAAEAVDTGAGCLFIVK
                     NYEGDVMNFEMAAEMSEGVQQIVTNDDVAVENSSYTTGRRGVAGTLVVEKIVGAAAEHG
                     LALASLKALGDRVNAATRSMGVALTSCTVPAAGKPTFDIGDGEMEFGVGIHGEPGRRRD
                     ALKSADAIAQEICAAILGDLGDKAKGPALLFVNGFGGTPLMELYLMYNSARLIFEKHGV
                     TVTRSLVGSYVTSLDMAGCSITLTMLDDETTAFWDAPVHTAALRWGM"
     gene            complement(13809..14231)
                     /locus_tag="M729_RS0134355"
     CDS             complement(13809..14231)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006206915.1"
                     /locus_tag="M729_RS0134355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_013528088.1"
                     /transl_table=11
                     /translation="MVDRTPEPGSEEAIRAYKTILSQVIDQRPSGMRQRLADALGKHRS
                     FVTQISSPAYSIPIPSKHLPAIFSVCHFSPAERDQFLAAYHQAHPGKMSIASGMRKTRH
                     VSLIVPDFGDDKQNAALDKAVNDFIQKITSITGKSG"
     gene            complement(14243..15829)
                     /gene="ptsP"
                     /locus_tag="M729_RS0134360"
     CDS             complement(14243..15829)
                     /EC_number="2.7.3.9"
                     /GO_function="GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA]"
                     /GO_process="GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene="ptsP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528087.1"
                     /locus_tag="M729_RS0134360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="WP_024501817.1"
                     /transl_table=11
                     /translation="MSEPLRLQGISASAGYAEGPLFDLDQTVVSYVGKETADDEKAALE
                     AAIAVATSRLTALSEMAEGDAADILEFQIAMLQDDALSSPAFAAIRTGLPADKAWRQAL
                     DTEIAGYDASDQDYFRARAADIRDIRDQVLRALSEDGDVQAPTGAILYGWDIAPTRFLE
                     TDWSSGGGIALKAGSTASHVAMLARSRGVPMVVGLGTSLARLTGTALLDAEHGGIVLSP
                     SKTEIAAFRQSSSSFRARSDRAGTFLARPAVTKAGTAVRVQVNIADPSDVDLIDITTCD
                     GVGLMRTEFLFGKTLPDEETQYRAYRKVLEWAGEKPVTIRTVDAGGDKPVPGFTIEESN
                     PFLGLRGIRLSLARPEVFRVQIRALLRAAVHGSLKVMFPMIAIVEEYRQAAAMFAEEQT
                     ALAARGVAHNMPPLGIMVEVPSVAIVPEAFTDAAFFSIGSNDLTQYVMAAARDNAAVAH
                     LNSVRHPAVLRLIAAVTAFGQREEIPVSLCGDAAGDPASIPSLIEAGLRDLSVAPAQLA
                     MAKAAIADVSV"
     gene            complement(15813..16115)
                     /locus_tag="M729_RS0134365"
     CDS             complement(15813..16115)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010913107.1"
                     /locus_tag="M729_RS0134365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HPr family phosphocarrier protein"
                     /protein_id="WP_013528086.1"
                     /transl_table=11
                     /translation="MSASAEATVVITHEVGLHARPSVKFTKLAKSFAAEVEIALAANGP
                     WFDAKSIVKVMAAKAPKGTVLHIRASGDGANDAVDALVELVRRDFDEGADHVRTA"
     gene            complement(16138..16527)
                     /gene="dhaM"
                     /locus_tag="M729_RS0134370"
     CDS             complement(16138..16527)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006206912.1"
                     /locus_tag="M729_RS0134370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="WP_027164279.1"
                     /transl_table=11
                     /translation="MSNVGIVIVSHSPLVAEGTADMVRQMVGDEVPLAWCGGNGHGGLG
                     TNVEAIMGAIDKAWSEAGVAILVDLGGAETNSEMAVEMIGEPRSHKIIVCNAPIVEGAV
                     MAATEASGGATLREVVATAHELSPP"
     gene            complement(16524..17126)
                     /gene="dhaL"
                     /locus_tag="M729_RS0134375"
     CDS             complement(16524..17126)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528084.1"
                     /locus_tag="M729_RS0134375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="WP_027164280.1"
                     /transl_table=11
                     /translation="MAALNLARLIAAAADTIAANAEELTALDQAIGDGDHGLNMKRGFE
                     AVRAEAEAFSAKPLPDALKAIGTKLVMTVGGASGPLFGTLFLALGKEISAKPDRANLTA
                     AFGKAIEAVAARGKSQIGQKTMLDVLQPVHDALLQGKTALEIADIADAGADATVPMKAL
                     RGRASFLGDRSIGHMDAGARSTALLVRTVAHSLGESA"
     misc_feature    complement(17168..17183)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.6"
                     /tool="antismash"
     gene            complement(17199..18842)
                     /locus_tag="M729_RS0134380"
     CDS             complement(17199..18842)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0004371 - glycerone kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528083.1"
                     /locus_tag="M729_RS0134380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="WP_027164281.1"
                     /transl_table=11
                     /translation="MKHFFNRRETIVTEALDGLLRTIGSGELARLDGYPEIKVVLRADW
                     DKTKVSVVSGGGAGHEPSHAGFVGRGMLTAAVSGEIFASPSVEAVLAAIRAVTGPAGCL
                     LIVKNYTGDRLNFGLAAEKARAEGFRVEMVIVADDIALPDITQPRGVAGTLFVHKISGH
                     LSEAGHDLAEIAAAARAAAKDIVSLGMSLSSCSIPGQPHEDRFGENDGELGLGIHGEPG
                     VERIAVQSADRLVAIMAERLAKRLDPKATYALLINNLGSVPPLEMSVIANAVLASPLAK
                     TIKLTIGPGPLMTALNMNGFSLSLIRLDAARETALQAPVGPHAWIPAKPAVSPAVVPMA
                     KAAGQSVARKPSQDARTRPLLVTICERLIALEATLNGLDAKTGDGDTGSTVATGARSVL
                     ERLDMLPLAEPAATLGAIGDILSASMGGSSGVLLSIFFTAAAQALGGGASLPRALLAGL
                     ERMTFYGGARIGDRTMVDALEPALKALDANGLEEAATAACHGAEATAAMDKAKAGRSAY
                     VGSKLQGVVDPGAHAVAEVFAAAAALHEAA"
     gene            complement(18898..19911)
                     /locus_tag="M729_RS0134385"
     CDS             complement(18898..19911)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010913111.1"
                     /locus_tag="M729_RS0134385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_027164282.1"
                     /transl_table=11
                     /translation="MAEVHIKNVTKSFGDHVAVDGLDLHIADGEFVVLLGPTGAGKTTT
                     LRLIAGLERPDSGTIEIGGHNATTLSPAERDTAFVFQQYSLYPHLSVFDNLAFPLRSPA
                     RKMPEDQIRRRVEEVAKMVRIHHKLANRSTKLSGGEMQRVAIGRALVRKPSIYLMDEPL
                     SSLDAKLRADLRLELKRIQTELGATMLYVTHDQIEAMTMADRIGILTEGVLAQIGSPRT
                     IYSEPANLHVAARLGQPAINLLPTGLLPDGGAPAGTKTIGARTEHLTIAKAANGHADGV
                     VDWVEHLGDQNHLHVTVGTKKLVTLTDPDTDLAQGDKVVIRYRAPLYFGADGQRLM"
ORIGIN
        1 gcgatgcgac gctcgatgtt gcgcgggcct atcccgggga tatcgtccgt gtcatcgccc
       61 tgccaagcaa tcgcggcccg ggcggcgcca ggaatgccgg cctcgatgcc gcccgcggca
      121 gatggatcgc ggttctcgat tccgacgacg cggtctttcc cggccggctc gccaggatga
      181 tcgcgcgtgc cgaaagcgcg gatgcccaga tcgccgtcga caatctgcag gtcgttcgcg
      241 aggacggcgt tatcgaggac gcgatgtttc cgcggcaata tctggaaggc ttgcgcgaga
      301 tttcgctggc cacctacatc gccggcaacg tcgtcttcga atccaagttc aacctcggct
      361 acctcaagcc gatcttccag cgcgagttcc tgaacgaaaa ccggcttcgc tatgacgaga
      421 agctgaggat cggcgaagac tacatcctct ttgccgccgc cctggccaac ggcggaaaat
      481 gcgtcgtcga gcccgatatc ggctatgcct accatattcg cagcgtctcc atttcgcgcg
      541 tgctcgagct tcaccacgtc gaagccatgc gcagggcgga tgccgtgttc gctcaaaccc
      601 atcggatgga tgaggccgcg caggccgcgt tcgcgcggcg tggccgcagc ctgcgcaagg
      661 cggcatcgtt tctgtcactg gtacagcaca tcaaggcgcg gtccccgctc aaggcgatcc
      721 ggactgcgct cagcgacccg gcggcggtca ggcatatggg catgccgatc gccgtgcggt
      781 tgcgaagaat ggcggcacaa tttgccgtcg gggcggggag gtgaagatgc aggcacatgg
      841 agggaatttt cgtggcctgt gaacggattg aagtcgatct cctcagaagg aatttgcgat
      901 gaagaaaatc aggaaggccg tgataccggt ggcggggctt ggaacgcggt tcctgccggc
      961 gaccaagtcg atgccgaagg aaatgcttcc cgtcgtcgac aggcctgtcg tccaatatgc
     1021 ggtggacgag gccttcgagg cgggcatcga gcacatcgtc ttcgtgaccg gtcgcaacaa
     1081 ggcggtgatc gaggactatt tcgacctgca tccggaattg atcggcaccc tggagcagac
     1141 cggcaagaag acccagctgg aggcgctcga aagcatgctg cctgtggccg gcgccaccag
     1201 cttcatccgc cagcaatccc cgcaaggcct cggccatgcc gtctggtgcg cgcgcgaggt
     1261 tatcggcaac gagcccttcg ccttgctgct gccggacatg gtgtccttcg gcggtcgcgg
     1321 atgcctcgcc gaaaccgtcg agctttatga gcgcacgggc ggcaacgtaa tcgccgtcga
     1381 gcgttgcgaa cccagcgaga ccaacaaata tggcatcgtt ggccgtggcg ccgagatcgg
     1441 cggcggtttc gaggtgacgg ccatggtcga gaagccggcg ccggccaatg cgccttcgaa
     1501 tttctacatc aacggccgct acatcctgca gccggagatt ttcgcgctcc tgggcaatca
     1561 gcagcgcggc gccggcaacg agattcaact gacggatgcc atggttcgtc tgtcgaagga
     1621 tcagccgttc ttcgcccagc ctttcctcgg ccgcatgttc gactgtggtt ccaaggaagg
     1681 gttcatccag gccaacatcg ccttcgcgct ggcgcgcgac gacatgaagg gtccggtttt
     1741 cgagatgctt caggagttcg tccggtcgca tgaacgccag gaagaagccg cataatgccc
     1801 atctttcggg agtatcgtca gatggccggc gaagaggggc cggcaggttc tctccgtctg
     1861 gcacgacgct tgcattgctc tggcgatgct cccgatcttc gaggcgcctg caagccaagg
     1921 catgatccct gaaagtgggt cccggtttcc ggaaaagatc atgttgaaac agtaagatag
     1981 agccaattgc gatcaatcgg aataggaccg gctctagaat tggaccgaag atgaattatg
     2041 ccaactttcc tctcgacaag aggatgccat tgccgaattc ggacgcagga gacggcgaag
     2101 acttcatcga tatcgagcgg ctgcttggca tggccgcacg gcaggccaag gtggttgccg
     2161 tgtgtgccgt catcggtctc ttcctgggcc tgctctattt gcagacaacg ccgcccaaat
     2221 atcagtcgat cgccagcgtg ctgatcgacg agggcttgaa caagatcgtc gacgacattt
     2281 cggcgacgtc gacaaccatg cagaccgatt ccgccatcct gagccagatc gagatcctga
     2341 cctcgacgcg gcttgccgcc gtggtcgtcg acaagctgaa gctcgaccag aacgacacgt
     2401 tcatgaatcc gccccagtcg gcgcttgccc aaggcatagg cctcatccgc agcctgatcc
     2461 agtatgtccg ccccagctct tccatgccgg gtggcgctga cttcagcaag ctcgacccgg
     2521 ccgcccgcga tgcgctgatc gccacgtcgc gccgcgacta cgcgatcctc aagctgcaga
     2581 acgagatccg ggcggaacgc gtcggccgaa gctacgtcat cgcgctcggc tatcaggcga
     2641 cggatccggc cttggcaaac gccatcacca aggcctatgc cgatgcctat ctcgccgatc
     2701 agctcgatgc cagcttcgat gccaccgagc gggctgcggt ctggctgcag ggccggttga
     2761 cggagctgcg ccagagctcg caggcagctt cgctcgcggt tgagaaattc agggctgaac
     2821 atgggctggc ggccaacagc gatggccagc tgatgagcga caagcagctt tccgacctca
     2881 acgcccagct tatcgtggcg caggccgaca ccgcacgcgc cagcgcccgc taccagcagt
     2941 acaaggccat cgtcgacagc ggctccgaaa acgctttcaa ggatgccgcc atatcgagcg
     3001 accagccaag cagctcggtc atatcggcgc tcaagacccg ctacctcacg gtggccaagc
     3061 ggctgcagga cgtcgaggcg aatttcggcc ccgagcaccc gcaggcggtg gctctctcca
     3121 aggagaaggc cgacatatcg acgcagattt tcggcgagct gaagcagctg accgaaagct
     3181 atcgcaacga atatgaggtg gcgcaggcac gcgagaccgc gctcagggcc aacgtcgcgg
     3241 ccgcgcaagg caagagttcc gtcgacaacc agacgcaagt caagctgcgt gaactcgatc
     3301 agcaggcgac ggcgctcacc acgctctatc agacattcct gggtcgttac gaggaagccg
     3361 cgcagcagca gtccttcccg gtcggcaaga tccgcatcat ctccgacgcg tcgatgccga
     3421 tgacggcctc aagcccgcgc accatcgtcg tgctcggact ttcgctggtg cttggcctgc
     3481 tgatgggcgc cggctttggt ggcctgaacg agtttaacga acgcttcttc aggaccggcg
     3541 aggacgtgcg cgaccgcgtc aacctgaaat tcctcggcta cctgccgacg atcggcggca
     3601 agctcggcaa ggaagaaaag ccgggcgaga cccaggtgga cgccaagacc acccaatcgc
     3661 tgtcttcagc cgaaaagcgg gcgcgcatgc gggtcagcat cgattctcca gcctcgatgt
     3721 tctccgaaac gctgcgcagc gccaagatcg ccttcgacgt cgtgatggaa gggcaaggca
     3781 gccgcgtcat cggcatcatc tcggtgcttc ccggcgaggg caagtcgacg gtcgcggcaa
     3841 atctcgccgg cttgcttgcc gccaatggct ccaagacgct gctgatcgac ggcgacttgc
     3901 gcaatcccgg cctcagccga ggccttggca tggaaaccga gcagggcttg atggaagcgg
     3961 tggtcggcgg ccagacctgg cagtccgtcg gcaagatcga caggcagacg aagctggcga
     4021 tcatcccggc ggtgctgcgc ggtcacttct cgcataccag cgaacttctc tcctcggccg
     4081 gcatgcggcg cttcatcgag aacgccaagg agaccttcga atacatcgtc gtcgatctgc
     4141 cgccgctcgg accggtggtc gacgccaagg ccttcgcgcc attggtcgac ggttttgtac
     4201 tggtcaccga gtgggggcgc accccgcgcg cgatggtcag gtcgatgctg gaatccgaac
     4261 cctatgtcgc caacaagatc gtcggcgcgg tgctgaacaa ggtcgatttg aagaaactgg
     4321 ccaaatacgg ctcgttcggc ggttcggaaa aattcttcga caaatattcg agctactatc
     4381 tggaaaagtc ggaagtgcgc ggcaaggcgc cggtctgacg tcgaccgttg cgcgagtggg
     4441 tccactctga agtgtatcga tcttcaggcc agcacacctg aatatcgttg cgcgtcagga
     4501 gaagatcagc ctgccttgct tgtcggcgat cctgacggcg gtcaggcgtc cgctctggaa
     4561 ggcggccgtg tcgatgccga gccggcgccc ttcgagcttc gggacatcca ccggcgtatg
     4621 cccgtgcacc acccagcggt cgagcaggtg cgttgcctcg aagaagtccg aacggatgtt
     4681 gatcaggtca tggtcggttt gcgccgcaag gtcgacgccg ggcctgatgc cagcgtggac
     4741 aaacacgaac ttacgcgaac ggaccatgat cggcagcccg cgcaggaagc tgacgtgatc
     4801 gtccggaatg atctccctta tgcgccggtc gatctgcgcg ctgctcccgt agaggctggt
     4861 gaggcgcgcc ggatcgatgc cataggaaaa cagggtttgc aggccgcccg tcgccagcca
     4921 gggttcgcgg gacagatttc cgtcgagata gttcagcatt gccacttcgt ggttgcccgc
     4981 aagacaaatg cgctgaaatc ctttcggcgg cggcgccagg aggtgatcga gcacccgcgc
     5041 cgactgaaat ccccggtcga tgtagtcgcc aagcatgacg atgatcttgc ggctctggaa
     5101 gcgcagcgaa tcgagcagga tcttctgctc cagcgcgcgg agttccttgt agcagccatg
     5161 cacgtcgccg atcgcataga cgacggcgtc ctgcatgtcg atatcgaggc gcggacgcgc
     5221 cgcgatgcgg ggttttcgct ggaacagggt cacgtgccgg gcgtctcgag gcaagctctc
     5281 atgccgaagg cataagtgcc tgttatcatg cccgaaacga agaattccgc aatcgtggaa
     5341 aatgcagctg cgccgggtcg gcaccgccaa tgcatgtcgc tcggaagtga gctccgtttt
     5401 gggagagcga tccgtggaac aaaggcctgg agtgggcctg aatccgctca ggcgcgacat
     5461 gctttaggtc ggcggccggc ccggtctgcc ggaccgtcgt caggctgcct tgagccgata
     5521 acggaaaacg gtatggtcga gcagcagccg gatgcgtggt tcggcctcgg tcgccactag
     5581 ccagcttgcc gcgatcattg tcgcgccgac gaccgccatc gagaacagat gcggcagacc
     5641 ggcgcggacc aggatgccga gcagggccgc gccgacgaca tcgtgcagca ggtagagcgg
     5701 ataggtcatc agcccgatcc gacgccagcc gctccaggag aggtcgagcc gcagcgacca
     5761 cgccatcagc gcgatgccta tgaggaagat gaggatcggc ggggcgaagg gcatatcacg
     5821 cccgaccttc aggatatgaa cgtcgaccga actggcgatc tgcagcacac caccggccag
     5881 gaacagggcg cagaaggcta ggcgggcggc tgtcaccgcc ttgaagcgca tcagccacag
     5941 catgacgccg gtggcgaaga acacgccgtg atgcaccaga agcaggtcga gcgtgcgtgt
     6001 ttcggcaagg tcggcccagt cgagcgggta gtagaggcac cagaacagcg cgctgaccag
     6061 gccgatggcg agcgccacaa tttccattag atggaagcgg ccgagccgca gcaaggtcca
     6121 gacgacggca tagaaggcga tctcgatgcc gagcgtccag tagacgctgt ccacccatgg
     6181 cgcgtaaggg gcgaacaggc cggtgcggac gagcctgacg acggcatcgg tcggccagct
     6241 gaggccgacg atcaaaagca ccgccgcagt gaccggcgca cagatccaca cggccggcgc
     6301 cagccgtttc accctggctt cgaaaaaccg caggggtgtc gacctttcgg cgctgaaggc
     6361 gatgacgaag ccgctgatga cgaagaagat ctggacgccg acccagccgg attcgaccca
     6421 ggcgcctatt gccggctgcg ggggaacgcc gcccgtggcg cgcgccgaaa caccgtcagg
     6481 atacgcccac acccagaagc catagtggta gaccatgacc atgacggcgg cgagaaagcg
     6541 caggatgtcg acgccgccaa atgtaatctt ctgctgagcc atgcgacctt tgtcgatggc
     6601 cccccgcgaa cgactttagg gtgcattgct gcgtcgcaca ataaaagtat tgcttgccga
     6661 tcgaaaaggt cgtccgcggc ccacccttca gtggctcaaa gtccgattcc gcgctccttc
     6721 agcgccgcag tgatctcgtc gaggatgacc ggatcgtcga tggttgccgg catggcccat
     6781 tcctccttgt cggcgatctt ctgcatggtg ccgcgcagga tcttgcccga tcgcgtcttg
     6841 ggcaggcgct tgatcgtcac caccgtcttg aaggcggcga ccgggccgat gcgttcgcgc
     6901 accaggccga ccacctcgtt ctcgatggag ccgatatcgc gggtcacacc cgcattcagc
     6961 accacgaagc ccagcggaac ctggcccttc atggcgtcgg caatgccgat gaccgcgcat
     7021 tcggcgacat cgggatgggc cgaaagcacc tcttccatgg cgccggtcga caggcggtgg
     7081 ccggcgacat tgatgatgtc atcggtgcgg gccatgacgt agagatagcc gtcctcgtcg
     7141 accatgccgg catccgccgt cttgtagaag ccggggaact cgtcgagata ggcttggcgg
     7201 aaccgttgat cggcattcca cagcgttggc aggcagccgg ccggcagcgg cagtttgatc
     7261 accacattgc ccagcgtgcc gcgctgcacc tcatggccag catcgtcgag aacgcggatg
     7321 tcgtagccgg gcatcggcac gccgggcgag ccgtatttca ccggcagcag gccaaggccg
     7381 gcgggattga tcgtcatcgg cgagccggtc tctgtctgcc accaatggtc gaccacaggc
     7441 acattcagct tctgctccgc ccatttgatg gtttccgggt cggcgcgctc gccggcaaga
     7501 aacagcgtgc ggaacttcga gaggtcgtgt ttggcaatga actcgccctt cgggtcctgc
     7561 cccttgatgg cgcggaatgc ggtcggcgcg gtgaacagcg cgaccacgcc atgctccgct
     7621 atcacccgcc agtaggtgcc ggcatcgggc gtgccgacag gcttgccctc gaacaggatg
     7681 ctggtgcagc catgcagcag cggtccgtag acgatgtagg aatggccgac cacccagccg
     7741 acatcggatg ccgcccagaa cacctcgccc ggcttgacgc cgaactcgtt ttccatcgtc
     7801 catttcagcg cgaccatatg gccgccattg tcgcgcacga tgcccttggg ctgaccggtc
     7861 gtgcccgatg tgtagatgat gtagagcgga tcggtggcaa gcaccggaac gcagtcgaca
     7921 ttggcgcccg ctgcccgttc gcgggcgacc gcatcggcgt agtcgatgtc gaaatgctcc
     7981 ttcaactcgc atcgcaactg gtcgcgctgc aggatcaggc aggcgtccgg cttgtggcgg
     8041 gagatctcga tcgccttgtc gagcaacggc ttgtaggcaa cgacgcggcc tggctccagg
     8101 ccacaggatg ccgaaatgat cagcttcggc ctggcatcgt cgatgcgggt ggcaagctca
     8161 tgcgaggcga agccaccgaa gaccaccgaa tgcaccgcgc cgatgcgggc gcaggcgagc
     8221 atggcgatgg ccgcctcggc caccatcggc atgtagatga tgacgcggtc acccttgccg
     8281 atgccgcggt tcttcagcac cgaggtcagc gcgacgacct cgcgcttcag ctcggcataa
     8341 gtgaactttt tcacggttcc ggcaatcgca ctgtcgtgga tcagcgcgat ctggtcggcg
     8401 cggccgccgg cgacgtggcg gtcgatggca ttgtagcagg tgttgcaggt ggcgccggtg
     8461 aaccagcggc catagacacc ggcattggcg tcgaacacct tgtcccaggg cgaataccag
     8521 tcgatggcgc cggccgcatc cgcccagaat tgttccggat cgcgtttcca gccttcatag
     8581 acctcgtgat agcgtgaagc catccatacc tccccgggaa atgtttttct tccttccaga
     8641 tagcgcgctc tacccttggc cgcaaatcca cgccattgtg acgacggcat cgacctggcg
     8701 cttgggggca agcagctatg aactgcgaga cgggactggg gtggtgatgt ctgctgctgt
     8761 tcggatcatc gggcgctttt cgctatcgtc ggtcatgggc gccgtacttg ctatgtccac
     8821 cggaaccgct gaagccggcg atgccgcggc acggcacatc atcggctttt cgccggatgg
     8881 cgcttatttc gccttcgagc aatatggaac gctcgacgcc ggcgcctcgg actccggctg
     8941 gtctgagatc gacatcatcg atacccgtac ggatcggttc gttggcggta agccgatcct
     9001 cgtcgtcgat gagacggagg aggcgacact gacgctggag caggcgaggg cgcaggccgc
     9061 cgctcaggcg gcgcccattc tcgcccatta tgcaatcaca tccccagccg agcagacagc
     9121 gtccgacaaa ttcacctttc cgggtgaaat ggttgcctac aacgacatct cccgcctcga
     9181 acaggtgtcg cagaaatggc tgtcgccgct ccatggcgaa acgggcgttt cgaccatcca
     9241 gctcgacgag atcctggcag ccagcacggg cgattgttcg gcgagtttcg caacgacgga
     9301 gcggcgcgac acatctggca aggcactcgg cttccggctg acgctgcaag gccaggacgg
     9361 caagccggtc aagatcctgc acgaggacaa gaccgtgccg ggctcaagaa actgcccgac
     9421 ctcctacagc ctgtcggaat cctacgaact taccccggcc ggcaagctgc cggtaattgt
     9481 cgtgctggtg cagcgtttta gccagggttt cgaggggcgc gatcgccgct tcctcgcagt
     9541 gaccgggcag ccacgctgag aggtcagccc caggcgccgg cagccgctct gtctgaaggt
     9601 tgtttctaga tcggcagggc cacaagcata aggccaatgc cgccagcgat caaaatggct
     9661 gtcgccagcg cttttctgtg acgttcgaag ctcgtcggag ctcgctccca attgtaacgc
     9721 atacgctatc tccccaatac ccaggcaggt tttaccttac ttaggggaag aaatgcaacg
     9781 tccgctgccg gcagcccgct gtttgtcacg tttcatcgat gactatttct gggccgaatg
     9841 cggccgggaa gacgcaaccg agcaggttct aacgcgactg gcgcggaaaa tctgtcagca
     9901 aggccgttgg tccgtgcacc gggctcccgt gatcggctga tagacagcgc tccacctccg
     9961 cgctatctga tttccgggat gagcatggct tggagggggc gtggtggaaa tagtctctgg
    10021 aaccgttctg cggctggccg aggatgcctc ggtgcagcat gtgggcgatg gcgcagtcgt
    10081 gcttttggcg cgcagcggcc agctctatac atgcaacggc acgaccgaag cctttctcga
    10141 caaggtggac ggcgcgcgca acctcgacca gatcgtcgac ctgctttgcg aggagttcga
    10201 ggtcgacaag gggacgctcg atcaggacat ggcggcactg gccacggatc tgatctcgga
    10261 aggtatcctc gccgcgctag gtgcttgatg gctgacggcc cgctcctgcg cgctcttttt
    10321 cgctgccatc tctgggcgag cgcgcggctg atgccggtcc ttgtcaccaa ccggagcttc
    10381 gaggaggtgc tcagatgggc gccgctcgcc tcgtcgacgc cctatcgcgg tctgccgtcc
    10441 gcctacatcg tcgcgagcgt caaccgcacg gtccgccatc cctggctgat gcgtgaccgc
    10501 aggtgcttga gggaaggtct gctcggtcat cgtttcctgc gactagccgg cttcgatccg
    10561 gacctgcgct tcggcgtcga accgcagtcg atgcaagcgc agcgtctatc ggcgcattgc
    10621 tgggtctgcc tcgacggcaa gccggtggtc agcgacaagc ttcccggcat ggtcgagatc
    10681 tatcgtcatc atgccgatgc cgtaaaggcg cgtcccgctt gaccagacct tcagcctgct
    10741 atggcctcaa cggcctgatc cttggcatat cgaccgagcg ctccgagctg tggcaggatt
    10801 tcgaccggat gctgggcagc ctgcgcatag aggaacccgt cgcgccggac tttcgtcttg
    10861 agatcaccga aacagacacg ctggacgaga cacccaatgg atccctggtc ttcgatggcg
    10921 aggtgccgga ggatggtccc tgccggatga tcgaggatgg cggcattgtc catctggtct
    10981 ttcccgggcg ccaaaccgtt gcgatcaatg gtggggaagg ttgggccgaa ctccggatta
    11041 gcaccggtac gaaagccgcc tggacgccgt cgatgttggt cctggatgcc gcgctcgacg
    11101 ccggtggcca gcatatgctg catacggccg ggctgacctt gcctgaccgc gatgcggtgg
    11161 tgctggtcca cgccccgagc ggcaccggca agaccacgac gtcgctggcg ctggcaacac
    11221 agggctttgg cctctgctcc gacgacgcca tgatcctgaa tgtcgcttcg ggcaaggtcg
    11281 tggcctgggg cttgccgcgc gccgtcaaaa tccaccggaa ggctgccgaa atgatcccgc
    11341 aggtggcgcc atgccttggc cagacgtggg atcgcaacgg cgaacagccg gtctcgttag
    11401 aacggttggg gggtatcatc cgggtggaaa acgcatccgc ccggccggtg gcggcgcttc
    11461 tgcatctggc gcgttccgcc gacggccaga cccggctcgt cgccatggcc aggaccgacg
    11521 cgatggtggc cctggcagtg gacaatgtcc gcaccggtat gaccgggctg ctgccgatgc
    11581 agaagcgcag gctggcgacc atcgccgggc tggtcaatgc ggtgccgacc ttccagctcg
    11641 aagtaggcgg gcgccccgct gacgctgcgg cgctgatccg cgctaccctg gattgacgtc
    11701 aagtcaggct acttgcggcc tggccttggc caatctctgg atccaccgga aggcgtcgcg
    11761 gcgcaggcgc gagcccagtc tgtccctgga attgacgcca agcagcgtat tcgttgtgat
    11821 cagccgcctg gccagccgta tggagagatc gggcttgatg cggccggcga gttcgagcgc
    11881 gcggctctcg tcgaacagct ggccggtcac attgagcacg attgccaact ccagttcgat
    11941 gccggtcata cgggcagcgt cgaacaggcg tgcttccgct tcgggtgatt gcagcgcccg
    12001 caccccttgc agcacgtcca cgcaaagctg caatcggtgg aatttgtggc cgcccgcggc
    12061 gtgcacgatg gcgatcgtta gaagagccgc cggcgtgtcc gtggcttcgc cgtcgatggc
    12121 gcgcaattca gggaaaccca gcgacaggcg tcgccgcatg ccggtgtcat gcacgaggtc
    12181 gccatgcagt tcgaccagca ggctggaatt ctctttttcc agccatttga attcctgcaa
    12241 ttcgtaggat tcggcctcgt tgctgccaag ctcgaagctg catgccgcga tcacctggtt
    12301 tgccctggcc agattggcgg gttcgaccag gatgtcgatg tcggtgaagg gcctgtcggc
    12361 gacgttgcgg tagagctttc gcgcgaagac gggtcccttg acgatccgcg ccggaatatt
    12421 gtccgccgcc agtcccttca tgatgcggtc cccatgatac ttcaacagca tcgactggcc
    12481 ggtggcgatc gttgccttct ggcgcagatc ctccagcttg ccgtgcaggt cggcatccgc
    12541 tggcagccgc gcgtccccgc tgagcttgcg caacatgatc ggcagcacgc cgtgaaactc
    12601 ggcattgtcg agcagcgccg tcagcgtctt tgccgacaaa tcttcgccgc ctgccgccgc
    12661 ctcggggtca gcgaagcgca gcaagagtct ttcttcggcg gaagtaagcg gtggcagcat
    12721 caacccagct agcattgcga gcaagtcagg aatggttgca gaaaagccta atgtaagcca
    12781 gcttttacat gccccagcgc agcgccgcag tgtgtaccgg cgcgtcccag aatgcggtcg
    12841 tctcgtcgtc gagcatggtc agcgtgatcg agcagccggc catatcgagc gaggtgacgt
    12901 aggagccgac cagcgaacgg gtcaccgtca cgccatgctt ctcgaagatt agccgtgcgc
    12961 tgttgtacat cagatagagt tccatcagcg gcgtgccgcc gaagccgttg acgaacagca
    13021 gcgccgggcc tttcgctttg tcgccgagat cgccgaggat cgcggcgcaa atctcctgcg
    13081 cgatcgcatc ggcgcttttc agcgcatcgc gccggcggcc gggctcgcca tggatgccga
    13141 cgccgaactc catctcgccg tcgccgatat cgaaagtcgg cttgcccgcc gccggcacgg
    13201 tgcaactggt cagcgccacg cccatcgagc gggtagcagc gttgacgcgg tcgccaagcg
    13261 ccttcagcga cgccagagcc aggccgtgtt cggccgccgc gccgacgatc ttctccacca
    13321 ccagcgtgcc ggcgacgcca cgccggcccg tcgtatagga agaattctcg accgcgacat
    13381 cgtcattggt cacgatctgc tggacgcctt ccgacatttc ggccgccatc tcgaaattca
    13441 tgacgtcgcc ctcgtagttc ttgacgatga acaggcagcc ggcgccggtg tcgacggcct
    13501 ctgccgccgc cagcatctgg tccggtgtcg gcgaggtgaa tacctggccg gggcaggcgg
    13561 cgtccagcat gccgtgaccg acaaagccgc catgcagcgg ctcgtgaccg gaaccgccgc
    13621 cggagatcag cgccaccttg cccggccgca aggtctttcg gcggatgaat ttgtgctcgt
    13681 cgccgagcac gaggatgtcg gcatgggcgg cgacgaagcc gtcgaggctt tcggtcagca
    13741 ccgtgtccac cgaattgata aacttcttca cggccgtctc ctcccgaaat aggccagata
    13801 gcaagtgatc agccactctt gccggtgatg ctggtgatct tttggataaa atcgttcacc
    13861 gctttatcga gcgcggcgtt ctgcttgtcg tcgccgaaat ccggcacgat cagcgagaca
    13921 tgccgcgtct tgcgcatgcc tgatgcgatc gacatcttgc ctggatgcgc ctggtgatag
    13981 gcggcgagaa actggtcgcg ctcggccggg ctgaaatggc agacggaaaa tatagccggc
    14041 aaatgttttg acggaatcgg gatcgaatag gcaggactgg aaatctgcgt gacgaagctg
    14101 cggtgcttgc cgagcgcatc ggccaggcgc tggcgcatac cggacgggcg ctggtcgata
    14161 acctgcgaca ggatcgtctt gtaggcgcgg atcgcctctt cggaaccggg ttcgggtgtc
    14221 ctgtcgacca tgccggccgc gcctagacag aaacgtccgc gatggccgcc ttggccatgg
    14281 cgagttgcgc cggcgcgacg gaaagatcgc gcaggccggc ctcgatcagt gacgggatcg
    14341 aggctggatc gccggctgca tcgccgcaca ggctgaccgg gatctcttcc cgctggccaa
    14401 acgcggtcac ggcagcgatc agccgcagca cggccggatg acggaccgaa ttgagatgcg
    14461 ccacggcagc gttgtcgcgg gcggccgcca tgacatactg ggtgagatca ttggagccga
    14521 tcgagaagaa ggcggcatcg gtaaaggctt ccggtacgat cgccaccgac ggcacttcga
    14581 ccatgatgcc gagcggcggc atgttgtgtg cgacgccgcg tgcggcaagt gcagtctgct
    14641 cttcggcgaa catcgccgct gcctgtcggt attcctccac aatggcgatc atagggaaca
    14701 tcactttcag gctgccatgg acagcggcgc gcagcagcgc ccggatctgt acacgaaaca
    14761 cctcgggtct tgccagcgac agcctgatcc cgcgcaggcc gagaaacgga ttgctctcct
    14821 cgatcgtaaa gccgggcacc ggcttgtcgc cgccggcgtc aacggtgcgg atcgtcaccg
    14881 gtttttcacc ggcccactcc agcaccttgc gataggcgcg atactgcgtc tcctcatccg
    14941 gcagcgtctt gccgaacagg aattcggtgc gcatcaaccc gactccgtcg caggtcgtaa
    15001 tgtcgatgag gtcgacatcg gacgggtcgg cgatgttgac ctgcacgcgc accgccgtgc
    15061 cggccttggt caccgccggt cgcgccagga acgtcccggc ccggtcgctg cgcgcccgga
    15121 atgatgagga cgattggcga aaagcagcga tttcagtctt ggagggtgac aacacaatgc
    15181 cgccatgttc ggcgtcgagc agcgctgtgc cggttagacg agccagcgaa gtgcccaacc
    15241 cgacaaccat cggcacgccg cgtgaacgcg ccagcatggc gacgtggctg gcggtgctgc
    15301 ccgccttcag tgcgatgccg ccgccgctgc tccagtcggt ttcgagaaaa cgcgtcggcg
    15361 cgatatccca gccgtagagg atggcgccgg ttggcgcctg gacgtcgcca tcctcggaca
    15421 gcgcccgcag cacctggtcc ctgatatcgc gtatgtcggc ggcccgtgcg cggaaataat
    15481 cctggtctga agcgtcgtag ccggcaatct cggtatcaag cgcttgccgc caggctttgt
    15541 cggctggcag gccggtgcgg atcgcggcaa aggccgggct gctcagcgca tcgtcttgca
    15601 gcatggcgat ctgaaactcg agaatgtcgg cggcatcgcc ctcggccatc tcgctcaatg
    15661 ccgtgagacg gcttgtcgcg acggcgattg cggcttcgag cgcggccttc tcgtcgtcgg
    15721 ctgtttcttt gccgacatag gatacgacag tctggtcgag gtcgaacagt ggcccctcgg
    15781 catagccggc cgaggccgaa atgccttgca gtctaagcgg ttcggacatg gtccgcgcct
    15841 tcgtcgaaat cgcgccgcac cagttcgacc aacgcgtcga cggcatcatt ggcgccgtca
    15901 ccgctggccc tgatgtgcag cacggtgccc ttcggcgcct tggccgccat caccttgacg
    15961 atgctcttgg cgtcgaacca tggcccgttg gcggcgagcg cgatctccac ctcggcggca
    16021 aaactcttgg ccagcttggt gaacttcacc gaaggacgcg cgtgcaggcc cacctcgtgg
    16081 gtgatcacaa cggtcgcttc ggcggatgcg gacatgtctt tcaagcttcc cgttcgttca
    16141 cggcggcgac aattcatgcg ccgtcgccac cacttccctg agcgtagcgc cgccggaggc
    16201 ctcggtcgct gccatcaccg cgccttcgac gatcggcgcg ttgcagacta tgatcttgtg
    16261 cgaccgtggc tcgccgatca tctccaccgc catttccgag ttggtctcgg cgccgccgag
    16321 atcgaccaga atggcgacac cggcttccga ccaggccttg tcgatggcac ccatgatcgc
    16381 ctcgacattg gtgccgagcc cgccatggcc gtttccgccg caccatgcaa gcggcacttc
    16441 gtcgcccacc atctgccgca ccatgtcggc cgtgccctcg gcaaccagcg gcgaatgcga
    16501 gacgatgacg atgccgacat tgctcatgcg ctttccccga ggctgtgcgc cactgtgcgc
    16561 accagcagcg cggttgagcg cgcgccggcg tccatatgac cgatcgatcg gtcgcccagg
    16621 aacgaggcgc ggccacgcaa ggctttcata ggcacggtcg cgtcggcccc ggcgtcggcg
    16681 atatcggcga tttcaagagc tgtctttccc tgcagcagcg cgtcatgcac cggctgcagc
    16741 acgtcgagca tggttttttg tccgatctgc gatttgccgc gtgctgccac agcttcgatc
    16801 gccttgccga acgccgccgt cagattggcg cgatcgggtt tcgccgaaat ctccttgccg
    16861 agtgccagga acagggtgcc gaacagcggg ccggaggcgc cgccgaccgt catcaccagc
    16921 ttggtgccga tcgccttcag ggcatcgggc agcggtttgg ccgaaaatgc ttcggcttcg
    16981 gcgcgcacgg cctcgaagcc gcgcttcatg ttcagcccgt ggtcgccgtc gccgatcgcc
    17041 tggtcgagcg ccgtcaattc ctcggcgttc gcggcgatcg tatccgcggc ggccgcgatc
    17101 agccgggcaa ggttcaacgc cgccatgtca cccgcattcc cggtttccat cttgccggca
    17161 gtatcgaaag aacggtcatt cgacaactgg agcatacgtc aggccgcttc atgcaatgcc
    17221 gcggccgccg cgaagacttc ggccaccgcg tgagcgccgg ggtcgaccac accttgcagc
    17281 ttgctgccga cataggccga ccgcccggct tttgccttgt ccatggccgc cgtggcctcg
    17341 gcaccatggc aggctgctgt tgccgcctcc tcaaggccgt tcgcgtcgag cgctttgagc
    17401 gccggctcaa gcgcatcgac catggttcta tcgccaattc tggcgccgcc gtaaaaggtc
    17461 atccgttcaa ggccggcaag cagcgctctg ggcaggctcg cgccgccgcc cagagcctgc
    17521 gccgccgccg tgaagaagat cgacagcagc acgccgctgg agccgcccat cgacgcgctc
    17581 agaatgtcgc ctatcgcgcc aagggtggct gcaggctcgg caagcggcag catatcaagc
    17641 cgctcgagaa cactgcgcgc gccggtcgcc accgtcgaac cggtgtcgcc gtcgcctgtt
    17701 ttggcgtcca gtccgttcaa agtcgcttcg agcgcgatca gcctttcgca gatggtaacg
    17761 agaagaggcc gggtccgcgc atcctggctg ggcttgcgtg ccacgctttg tccggccgct
    17821 ttcgccatcg gcacgacggc aggtgaaaca gccggctttg ccggtatcca ggcatgcggg
    17881 ccgaccggcg cctgcaaggc ggtttcgcgc gccgcatcca gccggatcag cgacagcgag
    17941 aagccgttca tgttgagcgc cgtcatcagc gggcccgggc cgatcgtcag tttgatggtt
    18001 ttagccaacg gcgaggcaag caccgcattg gcgataacgg acatttcgag cggcggcacg
    18061 gagccgagat tgttgatcag caaggcgtag gtggccttgg gatcaagccg cttcgcaagg
    18121 cgctccgcca tgatcgccac cagcctgtcg gcgctctgca ccgcaatccg ctcgacgccc
    18181 ggctcgccgt gaatgccaag gccgagttcg ccatcgttct cgccaaatct gtcttcgtgc
    18241 ggctggcccg ggatcgagca ggacgacagc gacatgccga gcgaaacgat gtccttggcc
    18301 gccgcccgcg ccgctgccgc gatttcagcc agatcgtggc cggcttccga caggtggcct
    18361 gatatcttgt gcacgaacaa ggtgccagca acgccgcgcg gctgggtgat gtcaggcaaa
    18421 gcgatatcgt cggcgacaat gaccatctcg acacgaaacc cttcggcgcg cgccttctct
    18481 gccgccaggc cgaaattgag acggtcgccg gtgtagttct tgacgatcag caggcagccg
    18541 gccgggccgg tgaccgcgcg aatggcggcc agcaccgctt cgacgcttgg cgaggcaaag
    18601 atctcgcccg aaaccgccgc cgtcagcatg cccctgccga cgaagccggc atgtgaaggc
    18661 tcgtgcccgg ccccgccgcc ggagacgaca ctgactttcg tcttgtccca gtcggcgcgc
    18721 aggacgacct tgatctcggg atagccgtcg aggcgcgcga gttcgccgga gccaatggtt
    18781 cgtagcaggc cgtccagcgc ctcggtgacg atcgtttccc tgcggttgaa aaagtgcttc
    18841 atcgaattcg tcccgtactc gaaaaatcaa aaccggtgct gaatcaccga aaaccgctca
    18901 catcaatcgc tgtccatcgg cgccgaaata cagcggcgcc cggtagcgga tcaccacttt
    18961 gtcgccctgc gccagatccg tgtcgggatc ggtcagcgtc accagtttct tggtgcctac
    19021 cgtcacatgc aaatggttct ggtcaccgag atgctcgacc cagtcgacaa cgccgtcagc
    19081 atggccattc gcggccttcg cgatcgtcag atgctcggtg cgcgcgccga tcgtcttggt
    19141 gccggccggt gcgccgccgt caggcagcag cccggtcggc agaagattga tcgccggctg
    19201 gccgagcctc gccgcgacat gcaggtttgc cggctctgaa tagatggtgc gcggcgagcc
    19261 gatctgcgcc agcacgccct cggtgaggat gccgatgcgg tctgccatcg tcatcgcctc
    19321 gatctggtcg tgggtgacgt agagcatggt ggcgccgagc tcggtctgga tgcgcttcag
    19381 ctcgagccgc agatccgccc gcagcttggc gtcgagcgat gacagcggct cgtccatcag
    19441 atagatcgaa ggcttgcgca ccagcgcgcg gccgatggcg acgcgctgca tttcgccgcc
    19501 cgaaagcttg gtcgagcggt tggcgagctt gtgatggatg cgcaccatct tcgccacctc
    19561 ctcgacccgg cggcggatct ggtcttccgg cattttccgc gccggcgagc gcagcggaaa
    19621 ggcgagattg tcgaacaccg acagatgcgg atagagcgaa tattgctgga agacgaaggc
    19681 ggtgtcgcgc tcggccggcg acagcgtcgt ggcattgtgt ccgccgatct cgatcgtgcc
    19741 gctgtccggc cgttccaacc cggcgatgag ccgcagcgtc gtcgtcttgc cggccccggt
    19801 tggcccgagc agcacgacga attcaccatc tgctatgtgc aggtcgaggc cgtcgacggc
    19861 gacatggtcg ccgaaactct tggtcacgtt cttgatgtgc acctcagcca tgctgggccc
    19921 tccgttccga ggcgacatcg tggatcgcgg ttctcaccgc gcggcccgat cccttctcga
    19981 acagcgacag ccgcgcgctg ctcagcgtca ggccgacatg gtcgccggtg gcgagcctga
    20041 tttcggccgg tacgcgtgcc ttgatgatgc catccgccgt ctccaccgcg acgatctgcg
    20101 tggtgccgag atattcggtg ccgtagatgg cgccgcgcaa ttttgaggcg tcgtcgaagc
    20161 ggatgtgttc agggcggatg ccgagcgcca tgtcgccagg tgcgatgtcc tcgcgcacct
    20221 ccggcaccgc gaccttcgcg ccttgcacga tgatctccct ggcgcccttg gcgagcccgc
    20281 cgccaaat
//
