LOCUS       NZ_KI911320            22781 bp    DNA     linear   CON 04-JUN-2024
DEFINITION  Mesorhizobium sp. WSM1293 MesloDRAFT_scaffold_4.5, whole genome
            shotgun sequence.
ACCESSION   NZ_KI911320
VERSION     NZ_KI911320.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Mesorhizobium sp. WSM1293
  ORGANISM  Mesorhizobium sp. WSM1293
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Phyllobacteriaceae; Mesorhizobium.
REFERENCE   1  (bases 1 to 407418)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly                          :: ALLPATHS v. R37654
            country                           :: Greece
            environment :: Host; Plant root; Root nodule; Soil
            investigation_type                :: bacteria_archaea
            lat_lon                           :: 37.147182 24.514618
            project_name                      :: Mesorhizobium loti WSM1293
            sequencing_meth                   :: WGS
            biotic_relationship               :: Symbiotic
            rel_to_oxygen                     :: Aerobe
            finishing_strategy                :: Level 1: Standard Draft
            GOLD Stamp ID                     :: Gi08882
            Current Finishing Status          :: Level 1: Standard Draft
            Type Strain                       :: No
            Funding Program                   :: DOE-DD 2010
            Isolation Site :: Serifos, towards Hora from beach
            Host Name                         :: Lotus sp.
            Cell Shape                        :: Rod-shaped
            Motility                          :: Motile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28
            pH                                :: 5-8
            Gram Staining                     :: Gram-
            Symbiotic Relationship            :: Mutualistic
            Diseases                          :: None
            Phenotypes                        :: Non-Pathogen
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method                   :: ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: 454-GS-FLX-Titanium; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000513875.1-RS_2024_06_04
            Annotation Date                   :: 06/04/2024 01:41:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,732
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,524
            CDSs (with protein)               :: 6,524
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 76 of 144
            Pseudo Genes (incomplete)         :: 111 of 144
            Pseudo Genes (internal stop)      :: 9 of 144
            Pseudo Genes (multiple problems)  :: 45 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:13:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 324365
            Orig. end                         :: 347146
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KI911320.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 404574
            Source DNA and Organism available from Wayne Reeve
            (W.Reeve@murdoch.edu.au)
            Contacts: Nikos Kyrpides (NCKyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22781
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22781
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22781
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12781](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12781)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            275..1345
                     /locus_tag="M729_RS1000000136735"
     CDS             275..1345
                     /EC_number="3.1.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012863.4"
                     /locus_tag="M729_RS1000000136735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_081714202.1"
                     /transl_table=11
                     /translation="MKVAGLRPFLIAVLAAAGLNGLTDRCALAGESELHSARLVGRFLA
                     TGTQATFEWPGTAIEVEFQGAWLDVVLDDTGRNSMVVDVDGAVSRLDLKKGEHTYRVVS
                     DTVAARHAVRLVRRTEASFGATVLKDIRTDGSFLPPQPKTRSFLVIGDSISAGYGVEGK
                     DAKCRFSADTENQYLTFAAVVARRFGADVTTLAASGKGLVRNYDGSTNATMRDLYTRLM
                     PSRPDREQLPDTNVIVVHLGSNDFSGGARPPDFVARYADLLAQLRANAPGAMIYAGIGP
                     MLWGADLDAAVSAVNKAVAVRRAAGERKIALIRFDSPGGVASRGCDSHPNEIGQGHMAD
                     ELEARVKADLGWEETK"
     gene            1342..2448
                     /locus_tag="M729_RS0134170"
     CDS             1342..2448
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="M729_RS0134170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyltransferase"
                     /protein_id="WP_024501842.1"
                     /transl_table=11
                     /translation="MTVASTVGVESPTVLPDSTNVRRKLLGLQVLRFVAAFAVVLFHIG
                     SGFQIEFGLKENIFGFGASGVDIFFVISGFIIAYTTDEAKGAWQFCRRRIVRIVPLYWT
                     LTAGIVLIALMKPGLLNSTVVSGETILKSLFFIPFEKVDGSIQPLLFLGWSLNYEMFFY
                     AIYAACIACGLRGPLSPSMFIVVLVAMGQFIQSENVAWRFYTNPLMLEFVFGILLYLAY
                     VHSAKLFVGRTWLMLAIFVATIAIRQMIPDLPWLLANGVPAVVLTAAALSWSPPRTRAI
                     TFLVLLGDASYSLYLSHPYVIQLASKLLPHQSGLMAQGLAGIVACALSIAVSIVLYTMI
                     ERPAQALFNGLAARRQASSTLRKTENHI"
     gene            2704..4014
                     /locus_tag="M729_RS0134175"
     CDS             2704..4014
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013891497.1"
                     /locus_tag="M729_RS0134175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="O-antigen ligase"
                     /protein_id="WP_024501841.1"
                     /sec_met_domain="Wzy_C (E-value: 1.1e-20, bitscore: 68.8,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIPKSLLVDPEKNSVYGAFAVAVSIWAFSYSFIFGQVLILAYYA
                     VWLPLVLVDYRRFLRHLSSAWLPLLFAAYVCFSIFWSVAPGITARTAFQYLSHIACAYI
                     AARTVSVRALTIGALVGIFFILLYSLRVGNYSDDVLDGTYNFVGAFASKNQLGFVASLG
                     IYFSVVFLAFYRRGRLSLMLTAPLILLSAYLLFVSHSATSMASIPAVLALVTLLAMSKI
                     LSRRYRRVIFLIGAGLLVVTAFVALNLGLMDFVLGLFGKDSTLTGRTYLWEQGWNAVQK
                     SPILGVGYAAYWVQGFAEAERLWNEFYITTRTGFHFHNTYIEALVELGFVGATLVSLIV
                     LRTLYGHVSAVVFKTWRAEPVILAGVMVLLLIRSFVEVEILNPYFTGSFLMYYSFFKLA
                     RLPVTTRTRRSQAPADAATGEADWPRHAGRPAAAGSS"
     gene            complement(4136..5401)
                     /locus_tag="M729_RS0134180"
     CDS             complement(4136..5401)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /GO_function="GO:0015159 - polysaccharide transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs) SMCOG1186:
                     polysaccharide export protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019862833.1"
                     /locus_tag="M729_RS0134180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="WP_027164259.1"
                     /sec_met_domain="Poly_export (E-value: 4.7e-19, bitscore:
                     62.8, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEAFRGGPVSGRLRRARLLATCLAMALVVPHIAAAGDYRLGSQD
                     KLTIRVAEWQTVEGTFRDWSAVNGEYTVGPSGTLSVPFAGELPASGKTTSEIATAIGEA
                     LQKKLALSDRPEASVEMAQFRPFYISGEVQNPGQFPYVPDLTVLKAISVAGGIRRNADY
                     GPQLGKDLVTAKGNFDVSDDQRIRLIVRRARIDADMAGKASFDVPKEVEGDPRLPAIVA
                     DEMTILTADQKALKLKLEALDDLKGVLESEIESLQKKIVNQQQQVDLAQQQLASIGQLA
                     QKGLIANARLLDSRQSVADLQGKILDYETAILTAKQSISKAKQDAIDAQNTLSSNLATA
                     RQQTEADLNEAALKANMQKGLIAQATDPATVAAMTNDEQPALLYSLVRNIDGKTSEIAA
                     KEDTLVLPGDVIKVKLAPLASQ"
     gene            complement(5502..6179)
                     /locus_tag="M729_RS0134185"
     CDS             complement(5502..6179)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006205264.1"
                     /locus_tag="M729_RS0134185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar transferase"
                     /protein_id="WP_013528120.1"
                     /sec_met_domain="Bac_transf (E-value: 3.6e-67, bitscore:
                     219.9, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDVAKSATASFSQADIDFPPPIGGLLKRSFDITGSLIGLIALSP
                     LFVMIALLVKFSDGGSIFYGHRRIGRGGRIFPCLKFRTMVPDGDKVLAAYLATNPDANA
                     EWIATRKLKNDPRVTRVGAVLRKLSLDELPQIINILQGDMSLVGPRPVVRDELEIYGTS
                     AVYYLKSRPGLTGLWQVSGRNDVSYDSRVAFDRHYVENWSLFEDVRIIIKTVPAVWMSR
                     GSY"
     misc_feature    complement(6313..6327)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.06"
                     /tool="antismash"
     misc_feature    6491..6504
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.66"
                     /tool="antismash"
     misc_feature    complement(6491..6505)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.31"
                     /tool="antismash"
     misc_feature    complement(6492..6505)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.25"
                     /tool="antismash"
     gene            6781..7056
                     /locus_tag="M729_RS0134190"
     CDS             6781..7056
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010913072.1"
                     /locus_tag="M729_RS0134190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exopolysaccharide production repressor ExoX
                     protein"
                     /protein_id="WP_013528119.1"
                     /transl_table=11
                     /translation="MALPKFILGMIFALAIVVGWSWLGGASIGTILVRVIICAVTIQAG
                     YFVLIYTMIARSAPTPADIARDAERKLNAPEVAESEKLGGARRGLH"
     gene            complement(7165..9009)
                     /locus_tag="M729_RS0134195"
     CDS             complement(7165..9009)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528118.1"
                     /locus_tag="M729_RS0134195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_032809899.1"
                     /transl_table=11
                     /translation="MSKPPILRLSLFREIAAFGATIARIGGRRTWTALFFLILGSLTEG
                     ISILLLVPLLHLVGRADQDFAVRLPNDDFVRWLVPDGTLQLTTVLCALVGLVAAQAAFN
                     RFKSVYMAKLLFDFINRVRMNLFESIGKARWGVFTRMRSSDLDHALTGDIDRVQGAAFS
                     LLMLVQIAVLLAGYLLVSVFISPVMTLFAVVVGILMFVALRPFRARATAFGRVLTANRQ
                     DQYRTVSEFLGGIKVAKSLNVEDSYFAQLRSTLERMKADNIDYVRNSTIGTAVFQVASV
                     VGLSLFIYVALVRFNLSLAEIVVLLLVFMRIAPRFMDMQTQAQQVLINLPAFTAMRSLQ
                     ARFDAEREPGHTEFADAGTLSLNTGLNIRGVSFAYGDAVDKAVVSGITFGLPAGKVTAL
                     IGPSGSGKSTIADMLLGLLEPTTGKMLVDGVEIDASNRRRWRDQVAYVPQDVFLLHDTI
                     AANLRLAAPRASDGDLWAALRQAHAGEFVERLDLRLETVVGDRGVRLSGGERQRIALAR
                     ALLRKPSLLILDEATSALDWQNQSLIARSIDGLRGTMTILTIAHRPSMIAFADWVVAME
                     NGRIVEVGQYQRLKEKTGSRLSRMLLGEQSESEPADVA"
     gene            complement(9018..10004)
                     /locus_tag="M729_RS0134200"
     CDS             complement(9018..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528117.1"
                     /locus_tag="M729_RS0134200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine kinase"
                     /protein_id="WP_027164261.1"
                     /transl_table=11
                     /translation="MMPRNEPLALCNDDAFSHGRAKRERRFYRAYGLTIASEVTLPELQ
                     PAAPGAADVVIAVGAIDLPKPSPEAATDFRFEPDRQYLAWHAVGAFLITDSSRIDIEPA
                     PGVDDALLAFPLLGPIMALLLHRRGLLVLHASAIAAAGTSAIFMGDKGAGKSTTASAMI
                     RAGHRLLTDDVVALDLANPSEPMTVPGFPQIKLAADAAAAISLGEAEVRPQVHAAIDKM
                     QHRLNGGFSGDEVPATRIYILERGERADITPLPAIAALPAIIKFSYVTRFGRAALPGDF
                     ATAHLRQCSWIANHIGVYRLEVPTGLDRIGEAVELIEKDLSAGSRRL"
     gene            complement(10001..11923)
                     /locus_tag="M729_RS0134205"
     CDS             complement(10001..11923)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006205260.1"
                     /locus_tag="M729_RS0134205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_027164262.1"
                     /sec_met_domain="GATase_7 (E-value: 1.7e-27, bitscore:
                     90.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 5.3e-62, bitscore:
                     205.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGVAGILLRGANAPAVAAADIQQMLARMRHRGPDGSSWWLDTSI
                     ALGHAWLNTSDEVGPGPLTMAGGRLAITADCRLDNRDELLARLGIRDQSVADAIVLMRA
                     YLRWGEACPEHLQGDFAFAIWDDERQSLFCARDHFGVKPFYYHAADRRFAFASEIGPIL
                     GVEGIRARVSERQISGFLAGLPDDPQSTPYSDIFSLPARHSLTVTAQQVMLRRYWQIEP
                     SARPLRSDASEEFAHLFSQSVRNRMRGTSAVGAMLSGGLDSSSIACVASLQNAAARKPR
                     LPTFSLIFEKGSPMDERPFIDAVLDQQKVDATLIPVGNYAPFAEFERVLEEQEGTFLAP
                     GLTLTRGIYRTAGAKGIKVLLDGHGGDEVVSQGHGHLHELANGGRWMDLWREVRSASNT
                     YGDSTLGLYLQFLTLYGPAWRIARLRHMANRALNKIRKPAQVSRARSWRDLINPDLAKR
                     TELVDRFHRAGYMPPGVQASDALSHRWILSNGYVPHAFEVLDKAAANFGVEPRYPFWDK
                     PLVEFCLALPGEEKLSHGFGRYVLRRAMQGVLPEAVQWRRDKIDFTANLVNGMLRNHRD
                     LLEQLLVSDAKRIAPYVNLPQVSAAYARLLRQPDQAAPLDVQYVWRSASLSLWLRQLQH
                     GGSPA"
     gene            complement(11920..12297)
                     /locus_tag="M729_RS0134210"
     CDS             complement(11920..12297)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024862.4"
                     /locus_tag="M729_RS0134210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_024501836.1"
                     /sec_met_domain="PF13471 (E-value: 1.1e-19, bitscore: 65.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFLGHCLLVVATVRLGLTLLSYNRVRSLVTRLDARQCASMGELR
                     RVAWGVAAAARFVPYATCLTQALSGQYILARQGNESTIRIGIERGTGEQLKAHAWLVSD
                     NHIVLGGSIDGFAHLVDHGSR"
     misc_feature    12362..12377
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.86"
                     /tool="antismash"
     gene            complement(12467..12781)
                     /locus_tag="M729_RS0134215"
     CDS             complement(12467..12781)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528114.1"
                     /locus_tag="M729_RS0134215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_027164264.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.6e-31,
                     bitscore: 100.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.5e-20, bitscore: 66.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGELSDRDLGDHDSVCATKDAVACEFGDGLALLNLKSNVYYSLN
                     GVGAFIWDLIQEPRSIGDIRSAVLARYNVDPVRCQADVDALLKGLADNGLARRHHEALV
                     "
     aSDomain        complement(12488..12739)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M729_RS0134215_Stand_Alone_Lasso_RRE.
                     1"
                     /evalue="4.80E-32"
                     /identifier="RREFam002.1"
                     /label="M729_RS0134215"
                     /locus_tag="M729_RS0134215"
                     /protein_end="98"
                     /protein_start="14"
                     /score="100.8"
                     /tool="antismash"
                     /translation="SVCATKDAVACEFGDGLALLNLKSNVYYSLNGVGAFIWDLIQEPR
                     SIGDIRSAVLARYNVDPVRCQADVDALLKGLADNGLARR"
     gene            complement(12919..13071)
                     /locus_tag="M729_RS1000000138215"
     CDS             complement(12919..13071)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033528.1"
                     /locus_tag="M729_RS1000000138215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide"
                     /protein_id="WP_010913078.1"
                     /transl_table=11
                     /translation="MEQNVEKHEYETPSLTVHGSIETITQGGGGSTAIDASFPAHTPIG
                     DLTFS"
     CDS_motif       complement(12994..13071)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MEQNVEKHEYETPSLTVHGSIETITQ"
                     /locus_tag="M729_RS1000000138215_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12919..12993)
                     /prepeptide="core"
                     /locus_tag="M729_RS1000000138215_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-0.30"
                     /molecular_weight="2258.4"
                     /monoisotopic_mass="2257.1"
                     /core_sequence="GGGGSTAIDASFPAHTPIGDLTFS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MEQNVEKHEYETPSLTVHGSIETITQ"
                     /leader_location="[12993:13071](-)"
     misc_feature    complement(13349..13363)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.63"
                     /tool="antismash"
     misc_feature    complement(13350..13365)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.71"
                     /tool="antismash"
     misc_feature    complement(13357..13371)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.0"
                     /tool="antismash"
     gene            13584..14708
                     /locus_tag="M729_RS0134225"
     CDS             13584..14708
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013891487.1"
                     /locus_tag="M729_RS0134225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_013528113.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.3e-33, bitscore:
                     111.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALPDGSYERLRAAGCAGEVAYVQACLRLFFAGPGAGDVSMRHLD
                     GEKIAEIARLNKVAVFVLKALSRAPALQRPTKLFQWLDTYRRKTVSMNASCIMDSMAIQ
                     DVLRASEIDFVFLKGPFQQQLLYDDHFMKPSGDVDILVSPLGFFRARDALRKIGYEVSG
                     KSSSVWWVRFLGEQHMTRDDGPRSSTVDLHYRLQQPGSPSPRDADGFLRRKRQVEIAGA
                     TVPFTSVADTLLLSCISVAKALFNREPCAGYVCDIGASAGRLDEADQQRLLDAATAQGL
                     DDTLLLGLRAADVLLGGAGTLLSQRATRILPRIGNEDLLSMVIAPWLPSLRWPQRRTVL
                     WELCGRAPVRYLAEAGWAASADISRRIFERPASR"
     gene            14800..15822
                     /locus_tag="M729_RS0134230"
     CDS             14800..15822
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528112.1"
                     /locus_tag="M729_RS0134230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_027164265.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5e-23, bitscore:
                     76.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMTKSEVCVIIAAKNAAATIAVAIASALREPEVAEVVVVDDAST
                     DDTAGVARSADDGSGRLSVMRLDVNRGPSFARNAAIAGSKSPFISILDADDFFLEGRFR
                     NLFAGADWDFAADNIMLIRDDATGDATKIVAPQFAADPEFLDFERFVEGNISRRRVQRG
                     ELGFLKPVISRAFLDRHGLSYDESLRLGEDYELYARAVACGARFKVIRSCGYGAIVRAD
                     SLSGRHKTQDLKRLADADLALLAIDSLPEGSKAVLRRHERHVRDKYRLRNFLDVKAERG
                     LGSAAAYAFASLSNLVPIVQGVASDKLEALFRRVGLVSSQKSVPPLRFLMAGTSTGKER
                     "
     gene            16113..16508
                     /locus_tag="M729_RS0134235"
     CDS             16113..16508
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013891485.1"
                     /locus_tag="M729_RS0134235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_027164266.1"
                     /transl_table=11
                     /translation="MASIFGFRSRDPARDRQADVSRLDRLAKLFEQIAAEIEAERTGLE
                     NRYRTTSTNAAFLVEAMENGSASDKRSSEVSALTQSILNCERRIAALSRQDGMMKELRH
                     SLDTVFDEDASSATAAEFAWPAGAGRG"
     misc_feature    16647..16660
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.17"
                     /tool="antismash"
     gene            16663..17517
                     /locus_tag="M729_RS0134240"
     CDS             16663..17517
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528110.1"
                     /locus_tag="M729_RS0134240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 16 glycosylhydrolase"
                     /protein_id="WP_024501832.1"
                     /transl_table=11
                     /translation="MNWNPKPTTAIDAPPLAYRTGQAARRLGSLGALLLAALGGFLATP
                     SHAQDIPTSPSFVDDFKSFDRTRWYVSDGWNNGSHQNCTWSKNMVELSNGVLSLGFEKQ
                     TLKDRDYVCGEIQTKQRFGYGTYEARLKTDTGSGLNAAFFTYIGPSDKQPWDEIDFEVL
                     TKDTSKVQVNAYIAGKGKNEKLVDVPGGTEKAFNDYAFVWQKDSLRWYVNGQLVNTITD
                     PAKLPSHAQKIFFSFWGSDTMKGWMGAFADPGRKLSLQVERVAFTALGEPCQFPESLAC
                     SVK"
     gene            17585..18916
                     /locus_tag="M729_RS0134245"
     CDS             17585..18916
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152: nucleotide sugar dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872478.1"
                     /locus_tag="M729_RS0134245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="WP_013528109.1"
                     /transl_table=11
                     /translation="MNLTVFGIGYVGLVQAAVLAEVGHQVVCVDIDAAKVERLNQGLVP
                     IFEPGLENLVKENHAAGRIKFTTDAAAAVRHGEIQMIAVGTPPGEDGSADLKYVLAVAE
                     TIGREMDKPKIVVGKSTVPVGTCEKVKARIADTLKKRGREDLAFDVASNPEFLKEGSAV
                     ADCMKPDRIIVGTDSEDTEAVMRELYAPFNRNHEKMIVMDVRSAEFTKYAANCMLATKI
                     SFMNEMANLAEQLGADIEEVRKGIGSDPRIGYHFIYPGLGYGGSCFPKDVRALIKTAEG
                     VKFDAKLLRAVEERNNAQKSVLFDKVDRYFKGNLKGRTFALWGLAFKPNTDDMREAPAR
                     VLMEALWKAGANVQAYDPEAMQECQAIYGLRDDLLLCGTKEAALRGADALLIATEWKSF
                     RAPSFDAVKDALTTPVIFDGRNLYDPKVIARHGIEYHSIGRMAA"
     gene            19009..20451
                     /locus_tag="M729_RS0134250"
     CDS             19009..20451
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872476.1"
                     /locus_tag="M729_RS0134250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_013528108.1"
                     /transl_table=11
                     /translation="MVLDVKPEQITKNHFDLVAIGSGFGSAFFLHEFARRRKARILVLE
                     WGRHNTHEWQLEQNVNTDIEDETTYKTNSDKPWNYTIGLGGGTNCWFAQTPRFHPNDFR
                     LKSTYGIGNDWPISYDDVEPFYCDAEDIMSISGDPDMAAMLPRSKPFPQPPHRMSTPDR
                     MMKAAQPDQHFVMPTARARVPTAQRSSCCANLRCWLCPVDAKFTVNNGLMHVFEHPDIS
                     VCLGAEVRRLDHVGGAVRSVTFSHDGKEYQVSGDLFILGANAIQSAAIMLRSGLGGEFV
                     GSGLHESYGWNFEVYLDGVDNFDGSTITTGLNFGLYDGPHRSEHAAALVYFENRWQHGM
                     RAEKGRLRQALPLVVVTENLLDPENYVTLDADDNAFVSFKAPSDYAVKGMARALEKLPD
                     LLAPLPVEKLFDRGIRPTESHVQGTLRMGTGPADSVVDSGMIHHQLRNLVVVGTSTYPS
                     CSCANPSLTAAALSLRAASRIA"
     gene            20465..20914
                     /locus_tag="M729_RS0134255"
     CDS             20465..20914
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013891481.1"
                     /locus_tag="M729_RS0134255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_013528107.1"
                     /transl_table=11
                     /translation="MIEISRRSALAVLAGGVVSTGVAYATVSSFSDEDLVRVTLEKYLG
                     KLNIRIEHLQQFVLAFRDRNPWNFPSEKLSDAVTLVEELKLGAARRLLPRRKREDLLHF
                     DRWVVAEFHMLTDYAWRSSPNDPIRFTGWQSCTNPFANLEPPKLA"
     gene            20989..22068
                     /locus_tag="M729_RS0134260"
     CDS             20989..22068
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015314217.1"
                     /locus_tag="M729_RS0134260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_024501831.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.2e-14,
                     bitscore: 48.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLFAGGNGYPPEFSGGVQSSTHHLAEQLIEHGHEAAVLAALFG
                     DGVFGFKARAKMKLLRQPAVVDSYPGYPVVRAWFPWEAAGYAVDRLKPDVAVVQCHKSV
                     PIGKALQAEGVPLVVYLRNVEFHELGGDLRELHSALYIANSDFTARTYKKEFGIEAAVI
                     PPTINPAHYSTPTTGQFVTLINPYEEKGFELAVRIAGACREIPFLFVESWKLDDDHRAR
                     IEQTIAPLGNVVLESRTSDMKTVYGRTKILLAPSKWEEAWGRVASEAHCSGIPVIGSRR
                     GGLPEAVGSGGVVLDYDAPLADWVAAVRRLWNDNQEYDRLSSLARSFAGRPELDPDRQF
                     ITFFSILDRAMQQRARQAA"
     misc_feature    22357..22370
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
ORIGIN
        1 ggcatcacca tggaaaacat ccagatcacc ggcggagcgc tttggtagcg ctccagcggg
       61 gtgcttgcga aagtccaact gacggggact gaaaaggacc agtgtctaaa aaggcgccgg
      121 catcaggcgg ggcgcttccg cttgcgacga ccgccttagg acggattttt cgcacgcgcc
      181 ctgcatctcg catgtgcgaa aagttctttc gcatctgcga gaaaaggtgt ttactgctct
      241 tgtagcactc gccattctca caggctgact ctagatgaaa gtagccggtc ttcggccatt
      301 cctgatagca gtgttggcgg cagctgggtt aaatgggctc actgatcgct gtgcgcttgc
      361 cggggaatcg gagttgcaca gcgcgcggct ggttggtcgc tttttggcga ccggaaccca
      421 agccacattt gaatggccgg gaactgccat cgaggttgaa ttccaagggg catggctcga
      481 cgtagtgctt gacgacacag gccgcaacag catggtcgtt gatgttgacg gtgctgtatc
      541 ccgccttgac ttgaagaagg gcgaacacac ctacagagtc gtatcggata cggtggccgc
      601 ccggcacgcc gtgcgtcttg tccgccgaac cgaagcgtca ttcggcgcga ctgttctcaa
      661 ggatatccgg accgacggat cttttctgcc gccgcagccg aaaacccgca gctttttagt
      721 catcggcgac tccatctcgg cgggttacgg cgtcgagggc aaggacgcca aatgccggtt
      781 tagcgccgat accgagaacc agtacttgac ctttgccgca gtcgtggcgc gccgctttgg
      841 agcagacgtt acgacgcttg cagcatccgg gaagggcctt gtccgcaatt atgatggcag
      901 caccaacgca acgatgcgcg acctctacac gcgactgatg ccgtcacgtc ctgaccggga
      961 gcaactgcct gataccaatg tcattgtcgt gcatctcggc agcaacgatt tcagtggtgg
     1021 cgcgcggccg ccggattttg tcgcacgcta cgcggacttg cttgcccaat tgcgcgccaa
     1081 cgcgcctggc gcaatgatct atgccggtat cggcccgatg ctttggggcg ccgacctcga
     1141 tgccgcggtg tcggccgtga acaaggccgt ggcggtccgt cgtgccgcgg gtgaaagaaa
     1201 aattgctctg atacgattcg acagtccagg aggagttgct tcacgcggct gcgactcgca
     1261 tccaaatgaa atcggccagg gtcatatggc cgatgaactt gaggcccgtg tgaaagcgga
     1321 ccttggctgg gaagagacaa aatgactgta gcttcgacgg ttggcgtaga atcaccaacg
     1381 gtgctgccgg acagcaccaa tgttcgtcgc aagctgctcg ggctccaagt tctaaggttc
     1441 gtcgccgctt ttgcggtggt attgttccat attggaagcg gttttcaaat agagtttggt
     1501 cttaaggaaa atatctttgg gttcggagcg tcaggcgttg atatattctt cgtaatcagt
     1561 ggatttataa tcgcttacac caccgatgag gccaaaggcg cctggcaatt ctgtcgccgc
     1621 cgcatagttc gtatcgttcc gctctattgg acgctgacgg caggtatcgt gttgattgcg
     1681 ctgatgaaac ccggtctgct gaattcgacc gtcgtgagcg gcgaaacgat cctgaaatca
     1741 ctgttcttca tcccgttcga aaaggtcgac ggttcgattc agccgctgct ctttctcggc
     1801 tggagcctca attatgagat gttcttctat gcaatatatg ctgcgtgcat agcttgcggc
     1861 ctgcgcggcc cactgtcgcc atccatgttc atagtagttc tcgtggcgat gggtcaattc
     1921 atccagagtg aaaacgtcgc ttggcgcttt tatacaaatc cgctgatgct ggaatttgtt
     1981 tttggcatct tactttacct ggcatatgtg catagtgcga agcttttcgt gggacgtacg
     2041 tggcttatgc ttgcgatttt cgtggcgaca atagccattc ggcaaatgat acctgatttg
     2101 ccctggcttc tggcgaacgg cgtccctgcc gtggttttaa ccgccgccgc tttgtcttgg
     2161 tcgccccccc ggacgcgcgc gataacattt ctggttttgc tcggagatgc atcatactcg
     2221 ctctacctct cgcaccccta tgtgatccag ctggcgagca aactgctacc gcatcagtcg
     2281 gggctgatgg cgcaggggct ggccggcatc gtggcatgcg cgctgtccat agcggtatcc
     2341 attgtccttt atacaatgat cgagcgaccc gcgcaggctc tcttcaatgg cttggcagcc
     2401 cgtaggcaag cctcctcgac gctcaggaaa accgaaaatc atatctgact cgcgatggga
     2461 acaggccgcc cactgcctct ggatttgtga cggatcgccc ctgttccaag gtgcgacgac
     2521 tcggtatccg ccgcttggcc aattcgcgta agataagttg accggatttg ccattgagcg
     2581 ccgggcgcga taggttatat tgcactgcac aatggagaag ccgtttattg cacgcccatg
     2641 tctgcgaaaa atccggccgg ctcatggctt gccggcactg ggtcgtgtcg gcgggactct
     2701 gagatgaaga ttccaaagtc cctgctggtc gatcccgaga agaactcggt ctatggcgcc
     2761 tttgccgtag ccgtctcgat ctgggcgttt tcctattcgt tcattttcgg ccaggtgctg
     2821 atcctggcct actacgcggt ctggcttcca ctcgtcctgg tcgactaccg gcggtttctg
     2881 cggcatctgt ccagcgcctg gctgccgctg ctgtttgccg cctatgtctg cttctcgatt
     2941 ttctggtcgg ttgcgccggg catcacggca aggacggcgt tccaatatct ctctcatatc
     3001 gcttgtgcct atatcgcggc gcgcaccgtc agcgtgcgcg cattgacgat aggcgccctg
     3061 gtcgggattt tcttcatcct gctgtattcg ttgcgggtcg gcaattattc cgacgatgtt
     3121 ctcgacggca cctacaattt cgtcggcgcg tttgcctcca agaaccagct cggttttgtc
     3181 gcctcgctcg gcatatattt cagcgtggtg ttccttgcct tttacaggcg cggccggctg
     3241 agcctcatgc ttacagcgcc tctcattctg ctgtcggcct atctgctatt cgtctcgcat
     3301 tccgccacct cgatggcctc gataccggcg gttctggcgc tggtgacgct tcttgcgatg
     3361 agcaaaattt tgtcacggcg ctaccgccgg gtgattttcc tgatcggcgc cggtctgctg
     3421 gtcgtgactg cctttgtcgc cttgaatctc gggctgatgg acttcgtcct cggcctcttc
     3481 ggcaaggatt cgacgctcac cggacggacc tatctgtggg agcagggctg gaatgccgtg
     3541 cagaaatcgc cgattctcgg cgtcggctat gccgcctatt gggtgcaggg cttcgccgaa
     3601 gccgagcggc tgtggaacga gttctacatc accacccgca ccggcttcca cttccacaac
     3661 acctatatcg aggctcttgt cgaactcggc ttcgtcggag cgacgctggt atcgctgatc
     3721 gtgctgcgca cgctctacgg ccacgtgtcg gcggtggtct tcaagacatg gcgggccgag
     3781 ccggtgatcc tcgccggcgt gatggtgctg ctgctgattc gttccttcgt cgaggtcgag
     3841 atactcaacc cctattttac gggttccttc ttgatgtact acagtttctt caagctggcg
     3901 cggctgcccg ttactacccg cacgcggcgg tcgcaggcgc cggcggatgc ggccacgggt
     3961 gaagctgatt ggccccggca tgccggccgt ccggcggccg ctgggtcgtc ataagcaatc
     4021 aactcgcggg ttgaagtcag ggcagcggga agccttcgcc tggcaagcat ggtgctcagc
     4081 aaaaatccgc ccctcacggg acggattgag atgctggatg gtatcgggct gtgggctact
     4141 ggctggccag cggcgccagc ttgaccttga tcacatcgcc aggcagcacg agtgtgtctt
     4201 ccttggcggc gatttcgctg gtcttgccgt cgatattgcg caccagtgaa taaagcaggg
     4261 cgggctgctc atcatttgtc atggcggcca cagtcgcggg atcggtagcc tgggctatca
     4321 ggcctttctg catattcgcc ttcagcgcgg cttcgttcag gtcggcttcg gtctgctgcc
     4381 gggcggtagc gaggtttgaa ctcaaggtgt tctgggcatc gatggcgtcc tgcttcgcct
     4441 tgctgatcga ctgcttggcg gtgaggatgg cggtttcgta gtccaggatc ttgccctgca
     4501 ggtcggcaac cgactggcgc gaatccagca gtcgggcgtt ggcgatcagg cctttctgcg
     4561 ctagctggcc gatgctggcg agctgctgct gcgccaagtc gacctgctgc tgctggttga
     4621 cgatcttctt ctgcagcgat tcgatctcgg attccaaaac ccctttgaga tcgtcgagcg
     4681 cttcaagctt cagcttcagc gccttttggt ccgctgtcag gatagtcatt tcgtccgcga
     4741 cgatggctgg cagtctcgga tcgccctcga cctccttagg cacgtcgaaa ctggccttgc
     4801 cggccatatc cgcgtcgatg cgggcgcgcc tgacgatcag ccgaatgcgc tggtcgtcgg
     4861 agacatcgaa attgcccttg gcggtaacca agtccttgcc gagttgaggt ccgtagtcgg
     4921 cgtttcgccg gatgcctccg gcgacgctga tggccttcaa cactgtcagg tcaggcacat
     4981 atggaaactg gccggggttc tggacttcgc ccgaaatgta gaatggccgg aactgcgcca
     5041 tctcgaccga ggcttccggt ctgtctgaca aagcgagttt tttctgcaaa gcctcgccga
     5101 tcgccgttgc gatttcggac gtggtcttgc cggaggccgg cagttcgccg gcgaacggca
     5161 ccgacagcgt gccggatgga ccgaccgtgt actcgccatt caccgccgac cagtcacgga
     5221 atgtgccttc cacggtctgc cattcggcga cgcggatggt gagcttgtcc tgcgagccga
     5281 ggcgatagtc gccggcggcg gcgatgtgcg ggacgacgag ggccatggca aggcatgtgg
     5341 ccagcaaacg cgcccgccgc aggcggccgg aaaccgggcc gccgcgaaag gcttcgaaca
     5401 aatctgtttt caactcaacg ttccgatccg ctatagcccc atcgcccgat gagcttgcgt
     5461 cgaatggccg acgccaatgt ctggcattgg ccaccggccg gtcagtaaga accgcgcgac
     5521 atccagacgg ccgggacggt cttgatgatg atgcgaacgt cctcgaacag cgaccagttc
     5581 tcaacatagt gacggtcgaa ggcgacgcgg ctgtcatagg acacatcgtt gcggccgctg
     5641 acctgccaca ggccggtcag gcccggacgc gatttcagat agtagacggc ggatgtgcca
     5701 tagatctcta gttcgtcgcg cacaaccgga cgcggaccga caaggctcat atcgccctgc
     5761 aggatgttga tgatctgcgg caactcatcg aggctgagtt tcctcagcac tgctccaacg
     5821 cgggtgacgc gcgggtcgtt cttcagcttg cgggtcgcga tccattccgc gttggcgtcc
     5881 gggttggtgg cgagataggc tgctagcacc ttgtcgccgt ccggaaccat ggtgcggaac
     5941 ttcaggcacg gaaaaatccg tccgccccgc ccgattcgcc tgtggccgta gaaaatcgag
     6001 ccgccgtcgg aaaacttgac gagcagcgct atcatgacaa atagcgggct gagggcgatc
     6061 aagccaatca gtgaaccggt gatatcgaag ctgcgtttga gcaggccgcc gatcggcggc
     6121 ggaaaatcga tgtcagcctg cgaaaagctc gcggtggctg acttggcaac gtccctcatg
     6181 ccgtaaactc catgcgttga acgaatggtt caccacacga taccaaaaaa atgttgcagc
     6241 gcaacacaca atttaccacc ccgttgaaat agtcacgtca tgaaatgact aaataataag
     6301 cttgccatgc acaaatttcg gcatatttag cacatttgtg acaataaatg ggcacagacg
     6361 aaaaaataga ggcctttgtg gggcggtttt taggcggacc tacctatttg ccaaggcgag
     6421 gtacaaacta gtgcttcatc atgccgtgat gcttggtcaa aaccatataa aatactactt
     6481 aatattggcc attttactga aaaatatcga cgagaggata tcggcctagc tcccgttgcg
     6541 tgcattgcaa catggcagag tcgatcgcaa aagctcgatc aaaaataacc gaagttgccc
     6601 ttgccgccta ttgctcgcct taatagaatt gcaaattata cctgtcacgg tgacgacagg
     6661 tggaaaaggc cggaagcaac cggtcgagag tgggcgacct taacaagccc acatgacaag
     6721 ggacggcgct cgggtggggc aatcgcgata atacccgagc cggtttatgg gctgttgggt
     6781 atggcacttc caaaattcat cctcgggatg attttcgctc tggcgatcgt cgtcggctgg
     6841 tcctggctgg gcggtgcgtc gataggcacg atattggtgc gtgtcatcat ctgcgccgtg
     6901 accattcagg ccggctattt cgtgctcatc tacaccatga tcgccaggag cgcgccgacg
     6961 cctgccgaca tagctcgtga cgccgagcgc aaactgaacg cacccgaggt cgccgaaagc
     7021 gagaagctcg gcggtgccag gcgcggcctg cattgatgca gactgctcaa acgtggccgg
     7081 tttggcggca acgacatgct tcgagacaaa gggaccaaag cgccgcgtga atccgtctcg
     7141 gcgcgacgcg tcctggccgc cggctcacgc cacatcagcg ggttcgctct ccgactgttc
     7201 ccccaacagc atcctcgaca accggctgcc ggttttttcc ttcagccgct gatattggcc
     7261 gacctcgacg atacggccgt tttccatcgc caccacccag tcggcgaagg cgatcatcga
     7321 cggccggtgc gcgatggtca ggatcgtcat cgtaccgcgt aatccgtcga tcgacctggc
     7381 gatcagcgac tggttctgcc agtcgagcgc gctggtcgcc tcgtcgagga tgagcagcga
     7441 cggcttgcgc agcagcgcgc gcgcgagcgc gatgcgctga cgttcgccgc ccgagagccg
     7501 cacgccgcga tcgccgacca ccgtctcgag cctgaggtcg agccgttcga caaactcgcc
     7561 ggcgtgcgcc tgacgcagcg cggcccacag atcgccatcg ctggcccgtg gcgcggcgag
     7621 gcgcaggttc gccgcgatcg tgtcgtgcag gaggaacacg tcctgcggca cataggccac
     7681 ctggtcgcgc cagcgacggc gattgctggc atcgatctcg acgccatcga caagcatctt
     7741 gccagtggtg ggctccagca ggccaagcag catgtcggcg atcgtgctct tgcccgatcc
     7801 ggacggcccg atcagggcgg tgaccttgcc ggccggcagg ccgaaggtga tgccgctcac
     7861 caccgccttg tcgacagcat ctccgtaggc gaaggacacg ccgcgaatat tcaatcccgt
     7921 attgagggag agtgtcccgg cgtcggcgaa ctcggtatgg ccgggttcgc gttcggcgtc
     7981 gaaacgtgcc tgcaggctgc gcattgccgt aaaggcgggc aggttgatca gcacttgctg
     8041 ggcctgcgtc tgcatgtcca tgaagcgcgg cgcgatacgc atgaagacca ggagcaggac
     8101 gacgatctcg gccagcgaca ggttgaagcg gaccaaagcc acatagatga acaggctcag
     8161 gcccacgacg ctcgccacct ggaatacagc agtgccgatg gtgctgttgc gcacatagtc
     8221 gatgttgtcg gccttcatcc tctcaagcgt cgaccgcagc tgcgcgaaat agctgtcctc
     8281 gacgttcagg ctcttggcca ccttgatgcc gccgagaaat tccgagaccg tccggtactg
     8341 gtcctggcga ttggcggtca gcacacggcc gaaggcagtg gcccgtgccc ggaagggccg
     8401 cagcgccacg aacatcagga tgccgacgac cacggcaaac agcgtcatga ccggcgagat
     8461 aaacacggaa accaggagat agccggccag aagaacggcg atttgcacca gcatcagcag
     8521 tgagaaagcc gcgccctgga cgcggtcgat gtcgccggtc agggcatgat cgaggtcgga
     8581 actgcgcatg cgtgtaaaaa cgccccagcg cgccttgccg atgctttcga acaggttcat
     8641 gcgaacgcga ttgatgaaat cgaacagcaa tttggccatg tagaccgact tgaagcgatt
     8701 gaacgccgcc tgcgccgcaa caagcccgac cagcgcgcaa agcacggtcg tcagttgcag
     8761 cgtgccatca ggcaccagcc agcgcacgaa atcatcattg ggcagccgaa cagcgaaatc
     8821 ctggtcggca cgtccgacca gatgcagcag cgggacgagc agcaggatcg aaatgccctc
     8881 ggtcaggctg ccgaggatga ggaagaacag cgccgtccac gttcgccggc cgccgatccg
     8941 ggcaatggtg gcgccgaagg cggcaatttc tcgaaacagc gacaggcgaa ggattggggg
     9001 cttcgacatg gttgcgctca caaccgccgg ctgccagccg acagatcctt ttcgatcagt
     9061 tccacggctt cgccgatcct gtccaggccc gtcgggactt ccagccggta cacgccgata
     9121 tggttggcaa tccatgaaca ttgccgaaga tgcgccgtcg cgaagtcgcc gggcagggcc
     9181 gcgcggccga agcgcgtcac ataggagaat ttgatgatgg ccggcagggc ggcaatggcg
     9241 ggcaagggcg tgatgtcagc cctttcgccg cgctcgagga tatagatcct ggtcgccggc
     9301 acctcgtcgc ccgaaaagcc accgttcagg cgatgctgca tcttgtcgat cgccgcatgc
     9361 acttgcggcc gcacttccgc ttccccaagc gagatcgccg ccgcggcgtc ggccgccagc
     9421 ttgatctgcg gaaagcccgg aacggtcatt ggctcactcg gattggcgag gtccagcgcc
     9481 accacgtcat cggtaagcag tcgatgcccg gcccggatca tcgcacttgc ggtcgtcgac
     9541 ttgccggctc ccttgtcacc catgaagatg gcgctcgtgc cggcggcggc gatggcactg
     9601 gcatgcagga caagcaggcc gcgccggtgc aagagcagcg ccatgatcgg accaagcagc
     9661 ggaaacgcga gcagcgcgtc gtcgacgccg ggcgccggtt cgatgtcgat acggctggaa
     9721 tcggtgatca ggaacgcgcc cacggcatgc cacgccagat attgccggtc cggctcgaag
     9781 cgaaagtcgg tcgcggcttc gggcgagggc tttggcaggt cgatcgcgcc gacggcaatc
     9841 acgacatccg ccgcccccgg cgccgccggc tgcagttcgg gcaacgtcac ctccgacgcg
     9901 atggtcaggc cgtaggcccg gtagaagcgg cgttctcgct tggcccggcc atgcgaaaag
     9961 gcatcatcat tgcatagagc gagcggctcg ttgcgcggca tcatgcgggg ctcccgccat
    10021 gctggagctg ccgcagccag agcgacagcg aggccgagcg ccagacatac tggacatcca
    10081 ggggggctgc ctgatcgggc tggcgcagca gccgcgcata ggcggcactc acttgcggca
    10141 gattgacgta aggcgcgatg cgtttcgcat ccgagaccag cagctgttcc aggaggtcgc
    10201 gatggttgcg cagcatgccg ttgacgagat tggcagtgaa gtcgatcttg tcgcgccgcc
    10261 actgcaccgc ctccggcaat acgccttgca tggcgcggcg cagcacatag cggccaaaac
    10321 cgtggctcag cttctcctcg cccggcagcg ccaggcagaa ctcgaccagc ggcttgtccc
    10381 agaaggggta gcgcggctcg accccgaaat tggcggcggc tttgtcgaga acttcgaaag
    10441 catgcgggac atagccgttc gacaggatcc aacgatggct caaggcgtcg ctggcctgga
    10501 cgccgggcgg catgtagccg gcccggtgaa accggtcgac aagctcggtg cgcttggcca
    10561 ggtccggatt gatcaggtcg cgccagcttc gtgcgcgcga cacttgcgcg ggcttgcgga
    10621 tcttgttcag ggcacggttg gccatatgcc tcagcctggc gatgcgccag gccggcccgt
    10681 agagggtcag gaactggaga taaaggccaa gcgtgctgtc gccataggtg ttggatgcgc
    10741 tgcggacctc gcgccacaga tccatccatc ggccgccatt cgcaagctcg tgcaggtggc
    10801 cgtggccttg tgaaacgacc tcgtcgccac catggccgtc cagcagcacc ttgatgccct
    10861 tggcgccggc agtccggtag atgccgcggg tgagcgtcag gcccggcgcc aggaacgttc
    10921 cttcctgttc ttccagcacg cgctcgaatt cggcaaatgg ggcatagttg ccgaccggga
    10981 tcagcgtcgc gtcgaccttc tgctggtcga gaacggcatc gatgaagggc cgctcgtcca
    11041 tcggcgagcc cttctcgaaa atcagcgaga acgttggcag cctcggcttg cgcgcggcgg
    11101 cattctgcag gctggcgaca caggcgatag acgaggaatc gaggccgccg ctcagcattg
    11161 ccccgaccgc cgaggtccca cgcatgcggt tgcgcaccga ttgcgagaac agatgggcga
    11221 attcctccga tgcatccgac cgcaagggcc gcgccgacgg ctcgatctgc cagtatcggc
    11281 gcagcatcac ttgttgcgcg gtgacggtta ggctgtggcg ggccggcagg ctgaatatat
    11341 cgctgtaggg ggtcgactgc gggtcgtcgg gaagcccggc caggaagccg gagatctggc
    11401 gctcgctgac acgtgcgcgg ataccctcga cgcccaggat cggaccgatc tccgacgcaa
    11461 aggcaaaacg ccggtccgcc gcgtggtagt agaacggctt gacgccaaaa tgatcgcgcg
    11521 cgcaaaacag cgattgccgc tcgtcatccc agatggcgaa ggcgaaatcg ccttgcagat
    11581 gctccgggca ggcttcgccc cagcgcagat aggcccgcat cagcacgatc gcgtcggcta
    11641 ccgactggtc gcggataccg agcctggcca gcaactcgtc acggttgtcc agccggcaat
    11701 cggcggtgat ggcgagccgg cccccagcca tcgtcaaagg gcccggaccg acttcatccg
    11761 atgtgttgag ccaggcgtgg ccaagggcga tgctggtgtc cagccaccaa gaactgccgt
    11821 caggaccacg atggcgcatg cgcgccagca tttgctgaat gtcggccgcc gcgaccgccg
    11881 gtgcgtttgc tccgcgcaac aggattccgg cgacgccgct catcggctgc cgtggtcgac
    11941 gagatgggcg aagccgtcga tcgatccgcc aagcacgata tggttgtcgc tgaccagcca
    12001 ggcatgtgct ttcaactgct cgcctgtgcc acgttcgatg ccgatgcgta tcgtcgattc
    12061 attgccttgg cgggcgagaa tatactggcc ggagagcgcc tgggtcaggc acgtggcgta
    12121 agggacgaaa cgggccgcgg cggcaacgcc ccaggcgacg cgccgcagtt cgcccattga
    12181 ggcgcactgc cgcgcgtcga ggcgcgtcac caggctgcgt acacgattgt aggacaacag
    12241 cgtcagcccc agccgaactg tcgccaccac cagcaggcaa tggccaagga agatcatttc
    12301 cgagccagtc agggagaaaa tcctgaccag cccgcgccgg cttcccccgc gcttcgtctg
    12361 cttgacgttt gtttctctcg ccggttcctg ccgtaaagcc gtggcccgcg aagacaaggc
    12421 cggcgaaacc agggcccgtg aaaccaggga cttgtgctgg accggcttag acaagtgcct
    12481 catgatgccg tctcgcaagc ccattatcgg ccaggccctt cagcaatgcg tcgacatcgg
    12541 cctggcagcg caccgggtcg acattgtagc gcgcaagcac ggcgctgcgg atgtcgccga
    12601 tcgaccgggg ttcctggatt aaatcccaga tgaaggcgcc gacgccattc aggctgtagt
    12661 agacattgga tttgagattg agcagcgcca agccatcgcc gaactcgcaa gccacggcat
    12721 ccttggtcgc gcacacgcta tcgtggtcgc ccagatcacg gtcggatagc tccccgttca
    12781 tccccaaacc tcgctgacaa aacgctgcga catctccagg cggcgcagga gaaatcggga
    12841 ggctggcccc ccgacccctc ttacgtctgc ttttgaatcc agagtcccaa catgtcactc
    12901 tggaatcggc tgtaggtctc aggagaacgt caggtcgcca atcggcgtat gcgcggggaa
    12961 cgatgcgtcg atcgccgtgc tgccgccgcc gccctgggtg atggtctcaa tcgaaccatg
    13021 gaccgtcagg cttggcgttt catattcatg cttttcaaca ttctgttcca ttttactctc
    13081 cgatttagga ctggaaacgg cctgtcgagt gccgtcagca cttttatgct gcaatgcaat
    13141 agctgcacgg cagcatttat gagtcaagac tgttttactt tctgttaatc aattacggtt
    13201 gctggcgtcg tcacatgagc ggcatgccta aaacttgtca cttttttagc cgattccttg
    13261 tgcacgacga tcgctcccgt gctgattctt taagcatttg attttgcttg cataagctgt
    13321 ttgcgttgtg cctatattta ggcctctctg aaaagaattt ccatttgaga aatcgtccgg
    13381 agattgccta agccgacgtg gcaagggaca tttcaaccgc ggttttcact gctttccgat
    13441 gccacctcga tagacgcttt ggtggcaaaa attcgcactg cagaaggaaa ggctttacgg
    13501 catcgaggtt tttggtgatg cttgcttcgc acttgcagca taagtgtcgg cgcgaaacgc
    13561 tttcttggga gactgtgcgc taaatggcct tgccggatgg ctcatacgaa cgattgcgcg
    13621 ccgccggctg tgccggcgag gtggcctatg tgcaggcttg cctgcgattg tttttcgccg
    13681 gcccgggcgc gggcgacgtt tcgatgcgcc atcttgacgg tgaaaaaatt gccgagattg
    13741 ccaggctgaa caaggtcgcc gtctttgtcc tcaaggcgct ttcgcgcgca cccgcgcttc
    13801 agaggccaac taagcttttc caatggctcg acacctaccg caggaaaacg gtttcgatga
    13861 acgcgtcctg catcatggat tcgatggcga tccaggacgt gctgcgcgcc agcgagatcg
    13921 atttcgtttt tctgaagggt ccgttccagc agcaacttct ctacgacgac cattttatga
    13981 agccctcggg cgatgtcgac atcctggttt cgccgctcgg atttttcagg gcgcgtgatg
    14041 cgcttcgcaa gatcggctat gaggtatcag gcaagtcgag ctccgtctgg tgggtccgct
    14101 tcctcggcga acagcacatg acccgggacg acgggccgag gtcgtccacc gtcgatctcc
    14161 actaccgcct ccagcagccc ggctcgccaa gcccgcgcga cgcggacggg ttcctgcggc
    14221 gcaagcgaca ggtcgaaatc gccggtgcga cggtgccgtt cacctcggtg gccgatacat
    14281 tgcttttgtc ctgcatcagc gtcgccaagg cacttttcaa ccgggaaccc tgcgccggat
    14341 acgtctgtga tatcggcgcc agcgccggcc gcctcgacga ggcggatcag cagcgtttgc
    14401 tcgatgccgc taccgcgcaa ggtctggacg acacgctgct gcttggcctg cgcgccgccg
    14461 acgtgctact cggcggtgcc ggcacgctgc tgtcgcagcg cgcgaccagg atcctgccgc
    14521 gcatcggcaa tgaggatctg ctcagcatgg tcatcgcgcc gtggctgccg tcgctgcggt
    14581 ggccgcagcg gcgaacggtg ctttgggaac tgtgcggccg cgcgccggtc cgctatctgg
    14641 ccgaagcagg ctgggcggcg tccgccgata tcagccgccg catcttcgag cggccggcga
    14701 gtcgctgaag gtaaattgga tgctgatggc aattctgtag tgcatcgaac gagtacgggg
    14761 cgagggcaaa tcgatattac ctgtacgaga ggcaaatcca tgtcgatgac gaaatccgag
    14821 gtctgcgtga tcatcgcggc aaaaaacgcc gcagcgacaa tcgccgtcgc catcgcatcc
    14881 gcattgcgcg aaccggaagt ggcggaggtc gtggtcgtcg acgatgcctc caccgacgac
    14941 accgccggtg tcgcacgatc cgccgatgat ggcagcgggc ggctctccgt gatgcgcctc
    15001 gatgtcaatc gcggcccctc ctttgcccgc aacgcagcca tcgccggctc gaaatcgccg
    15061 ttcatcagca ttctcgatgc cgacgatttc ttcctcgaag gccggtttcg caacctgttt
    15121 gccggcgccg attgggattt cgccgccgac aacatcatgc tgatcaggga tgatgcgacg
    15181 ggcgacgcga cgaaaatcgt cgcgccgcaa tttgccgccg atccggaatt cctcgatttc
    15241 gagcgtttcg tcgaaggcaa catctccagg cgccgcgtgc agaggggcga attgggcttt
    15301 ttgaagccgg tgatcagccg tgccttcctc gaccgccatg ggttgagcta cgacgagagc
    15361 ctgcggctgg gcgaggacta tgaactctac gcccgcgcgg tcgcatgcgg agcgcggttc
    15421 aaggtcattc gctcctgcgg ctacggcgcc atcgtccgcg ccgattccct gagcggccgc
    15481 cacaagaccc aggacctgaa gcgtttggcc gatgcggatc tggcgctgct ggcgatcgac
    15541 agcctgccgg aaggctcgaa ggcggtgctg cggcggcatg aacggcacgt gcgcgacaaa
    15601 tatcggctgc gtaatttcct tgacgtcaag gccgagcggg ggctgggctc ggctgcggct
    15661 tacgccttcg ccagcctgtc caacctcgtc cccatcgtcc agggcgtggc ttccgacaag
    15721 ctcgaggcgc tgtttcgtcg tgtcggcctt gtgtccagcc aaaagtctgt gccgccgctg
    15781 cgctttctga tggccggaac cagcacgggc aaggaacgct gagagcggtc ccgatgcagc
    15841 gatttgtcca ctcgcggcat gtcatcacgc aaaccatttc ggtcggattt atgagtttac
    15901 gaattgggtg gttgcctcgc ggctccgacg atggcagtct atgttgcggt gcagcatagt
    15961 ggacgaccag ccgaacttgg cccccgatcg gattggtctg atgtctctcc ctcaaaagga
    16021 gcacgacaac gcaacacgag tttttgagcc ccggctgcgg ggatcggcca gaagcccggc
    16081 ccacaagccg gcgatgacgg gaacctgagt tcatggcctc gatattcggt ttcagatcaa
    16141 gggatccggc ccgcgaccgt caggccgatg tttcacgtct tgatcgtctg gcaaagctgt
    16201 tcgagcagat tgcggccgag atcgaggccg agagaaccgg gcttgagaat cgctaccgga
    16261 cgacgtcgac caacgccgcc tttctggtcg aagcgatgga aaacggctct gcttccgaca
    16321 agcggtcttc ggaagtcagc gcactgacac agtcgatcct gaattgcgag cgccgcatcg
    16381 cggcgctgtc gcgccaggac ggcatgatga aagagctccg tcattcgctg gatacggtct
    16441 ttgacgagga tgcctcctcg gccaccgcgg cggaattcgc ctggccggca ggcgccggca
    16501 gaggttgaac gtgaaggctc ggaactgttg caacagattt gatgcaaggc gggaagcaga
    16561 agcaatcgag agggtcacaa ggaaggtcaa ggttggcccg tgcaggagcg gttcgaacgt
    16621 cgactttggg ttggggacac acagcgcaaa ggtgagtttg gtatgaattg gaatccgaaa
    16681 cctacgacgg caattgacgc accgcctctc gcatatcgga ccggacaagc cgcccggcgg
    16741 ctggggtcgc tcggtgcgtt gctgctggct gctcttggcg gtttcctggc aaccccttcc
    16801 catgcccagg acattccgac atcgccgtcc tttgtcgatg atttcaaaag cttcgaccgc
    16861 acgcgctggt atgtttccga cggctggaac aacggcagcc atcagaattg cacctggtcg
    16921 aaaaatatgg tcgaactgtc gaatggtgtg ctgtcgctcg gcttcgaaaa gcagacgctg
    16981 aaggatcgcg actacgtctg cggcgagatc cagaccaagc agcgcttcgg ctatggcacc
    17041 tatgaggcac ggctgaagac cgataccggc tccggcctca acgccgcgtt cttcacctat
    17101 atcggtccca gcgacaagca gccctgggac gagatcgact tcgaggtcct gaccaaggac
    17161 acctccaagg tgcaggtcaa cgcctatatc gcgggcaagg gcaagaacga gaaactggtc
    17221 gacgtgccgg gcggcacgga gaaggccttc aacgactacg ccttcgtctg gcagaaggac
    17281 agcttgcgat ggtacgtcaa cggccaactg gtgaacacga ttactgaccc ggcgaagctg
    17341 cccagccatg cacagaagat attcttcagc ttttggggca gcgatacgat gaagggctgg
    17401 atgggagcgt tcgcggatcc gggccgcaag ctttccctgc aggtcgagcg ggtcgccttc
    17461 acggcgctcg gcgaaccctg tcaatttccg gaatcgctgg catgcagtgt aaagtagttg
    17521 ggaaagtcga tttgaaccgg cggggccgaa aacggtccgc tgccttgcat gggaatgaaa
    17581 ccgaatgaat ttgacggtgt ttggaattgg ctatgtcggc ctcgtgcagg cggcggtgct
    17641 tgccgaagtc gggcaccagg tggtgtgcgt cgacatcgac gccgccaagg tcgagcggct
    17701 caaccagggc ctggttccca ttttcgaacc cggtttggaa aacctcgtca aggagaacca
    17761 tgccgccggc cgcatcaagt tcacaacgga tgccgccgcc gctgtcaggc acggcgagat
    17821 ccagatgatc gcggtcggca cgccgccggg cgaggacggc tcggccgacc tcaaatatgt
    17881 gctggcagtc gccgagacca tcggccgcga aatggacaaa cccaagatcg tcgtcggcaa
    17941 gtcgacggtg ccggtcggca cctgcgaaaa ggtgaaggcc aggatcgccg acacgctgaa
    18001 gaaaagaggc cgcgaggacc tggctttcga tgtcgcttca aatccggaat tcctcaagga
    18061 agggtccgcg gttgccgact gcatgaagcc ggaccgcatc atcgtcggca ccgacagcga
    18121 ggacaccgag gctgtgatgc gcgaactcta cgcgccgttc aatcgcaacc acgagaagat
    18181 gatcgtgatg gacgtgcgca gcgcagaatt caccaaatat gccgccaact gcatgctggc
    18241 gaccaagatc agcttcatga acgagatggc caatctggcc gaacaactcg gcgccgacat
    18301 cgaggaggtc cgcaagggca tcggcagcga tccgcgcatc ggctaccatt tcatctatcc
    18361 gggcctcggc tatggcggct cgtgcttccc gaaggatgtg cgggcgctga tcaagaccgc
    18421 cgaaggcgtc aagttcgacg ccaagctgct gcgcgccgtt gaggagcgca acaacgcaca
    18481 gaaatcggtt ctcttcgaca aggtggaccg ctatttcaag ggcaacctca aaggcaggac
    18541 ctttgcgctc tggggtctgg ccttcaagcc caacaccgac gacatgcgtg aggcgccggc
    18601 gcgcgtcctg atggaggcgc tctggaaggc cggcgccaat gtgcaggcct atgatcccga
    18661 ggcgatgcag gaatgccagg ccatctacgg gctgcgcgac gacctgcttc tgtgcggcac
    18721 caaggaggcg gcgcttcgcg gcgccgatgc gctgctgatc gccacagaat ggaagagctt
    18781 tcgcgcgccg tccttcgacg cggtgaagga cgcgctgacc acgccggtca tcttcgacgg
    18841 ccgcaacctc tatgacccca aggtcatcgc ccgccacggc atcgaatatc actcgatcgg
    18901 cagaatggcg gcatgagacc gggccctggc agccggatgc aagaccggtc cgcacacggc
    18961 ctgcgggcgc tggggttgag cgcgtatttc tgtgtggagt tgtagctgat ggtgctggac
    19021 gtaaagccgg agcaaatcac caagaatcat ttcgatctcg tcgcgatcgg ttccggcttc
    19081 ggttcggcct tcttcctgca tgagttcgcc aggcgccgaa aggcgcgcat tctggtgctg
    19141 gagtggggac gccacaacac ccatgaatgg cagctcgaac agaacgtcaa caccgacatc
    19201 gaagacgaga cgacctacaa gaccaattcc gacaagccgt ggaactacac gatcggactg
    19261 ggtggcggga cgaactgctg gttcgcgcag acgccaagat ttcatcccaa tgatttccgg
    19321 ctgaaaagca cctacggcat cggtaatgac tggccgatca gttatgacga cgtcgagccg
    19381 ttctactgcg acgcggaaga catcatgtcg atctccggcg accccgacat ggcggcgatg
    19441 ctgccccgct cgaagccgtt tccgcaaccg ccgcatcgca tgtcgacacc ggacaggatg
    19501 atgaaggcgg cgcagcccga ccagcacttc gtcatgccaa ccgcgcgggc tcgcgtgccg
    19561 accgcgcagc gcagctcgtg ctgtgccaat ctgcgttgct ggctgtgccc ggtcgacgcc
    19621 aaattcaccg tcaacaacgg gttgatgcac gtcttcgagc atcccgacat ctcggtctgc
    19681 ctcggtgcgg aggtgcgccg gctcgatcac gtcggcggcg ctgtccgttc ggtcacgttc
    19741 agccatgacg gcaaggaata ccaggtcagc ggcgatctct tcattctcgg cgccaatgcc
    19801 atccagagcg cggcgatcat gctgcgatcc ggcctgggcg gcgagtttgt cggcagcggc
    19861 ctgcatgaat cctacggctg gaatttcgag gtctatctcg acggcgtcga caatttcgac
    19921 ggcagcacca tcacaacagg cctgaatttc ggcctctatg atggtcctca ccgatcggag
    19981 catgcggcgg cattggtcta tttcgagaac cgctggcagc acggaatgcg tgccgaaaag
    20041 gggcggctac gccaggcgct gccgttggtc gtggtcaccg agaacctgct cgaccccgag
    20101 aactacgtca cgcttgacgc ggatgacaat gccttcgtca gcttcaaggc gccatcggac
    20161 tacgcggtga agggcatggc gcgcgctctg gagaaattgc ctgaccttct ggcgccgctg
    20221 ccggtcgaaa agctcttcga ccgcggcatt cggccgaccg aatcgcacgt ccagggcacg
    20281 ctgaggatgg gcaccggccc ggccgattct gtggtcgaca gcggcatgat ccaccatcag
    20341 ctcagaaacc tggtcgtcgt cggcaccagc acctatccga gctgctcctg cgccaacccg
    20401 agcctgaccg cggcagcgct gtccttgcgg gcggcgagcc ggatcgcgtg aaaggaggta
    20461 tcgcatgatc gagatttcca gacgctcggc cctggccgtc ttggctggcg gagtggtttc
    20521 gacgggggtc gcctacgcca ccgtttcctc cttctcggac gaggatctgg tgcgcgtcac
    20581 gctggaaaaa tatcttggca agttgaacat ccgcatcgag catctgcagc agttcgtgct
    20641 ggcgttccgc gaccggaatc catggaattt cccaagcgaa aaactgagtg atgccgtcac
    20701 cctggtggag gagctcaaac tgggcgccgc gcgtcgcttg ctgccccggc ggaagcggga
    20761 agatctgctg catttcgacc gctgggtcgt cgccgaattc catatgctga cggactacgc
    20821 ctggcgcagt tcgcccaacg acccgatccg gtttaccggc tggcaatcct gtaccaatcc
    20881 cttcgccaat ctggagccgc cgaaacttgc ctgacgtcga aagcgaggcg gcggcctttg
    20941 cctgttgcct tcgagcaagg aatacgagat gcgacaagga gcccgatcat gaaagttctc
    21001 tttgcaggcg gcaacggcta cccgcccgag ttcagtggcg gcgttcagtc gagcacgcat
    21061 catctggccg aacagctgat cgagcacggt catgaagccg ctgtgctcgc cgccctgttc
    21121 ggtgacggtg tcttcggctt caaggcgcgc gccaagatga agctgttgcg gcagccggcg
    21181 gttgtcgaca gctatcccgg ctatccggtg gtgcgggcct ggtttccctg ggaagcggcg
    21241 ggttatgccg tcgacaggct gaagcccgat gtcgccgtgg tccagtgtca caaatcggtt
    21301 ccgatcggca aggcgctgca ggcggagggc gtgcctttgg tcgtttatct ccgcaatgtc
    21361 gagttccatg aactgggcgg cgatctgcgc gaattgcatt cggcgctcta cattgccaat
    21421 tcggacttca ccgcgcgaac ctacaaaaaa gaattcggca tcgaggcagc ggtgatcccg
    21481 ccaaccatca acccggcgca ttactcgacg ccgacgacgg gccagttcgt cacgctgatc
    21541 aacccctatg aggaaaaggg atttgagctc gcggtgcgga ttgccggcgc ctgccgcgaa
    21601 attccattcc tgttcgtcga aagctggaag ctcgacgacg atcaccgggc gcggatcgaa
    21661 cagacgatcg ctcccttggg caatgtcgtc ctggagagcc gcaccagcga catgaagacg
    21721 gtctatggtc gcacgaagat cctgcttgct cccagcaagt gggaagaggc gtggggccgc
    21781 gtcgcttcgg aggcccattg cagcggaatc cccgttatcg gttcgcggcg cggcggtctg
    21841 cccgaggctg tcggctccgg tggcgtggtg ctggattacg atgctccgct ggccgattgg
    21901 gtcgcggccg tcaggcggct gtggaacgac aaccaggaat atgaccggct ttccagtcta
    21961 gctcgcagct tcgccgggcg cccggaactc gatcccgatc gccagttcat caccttcttc
    22021 tcgatactgg acagggccat gcagcagcgc gcgcgacagg cggcctgacg acgccgcctg
    22081 agcaggtcag gccggacgct tgacccggct tttcagcgtc tcgtagccgc gggcgccaag
    22141 cagtgcgcgg gcaatggtct tggcggcgct cttgcggccc tcttgcgact tgatctgccg
    22201 cagccttgcc ggcaggttgc gggccgcctg gccaagtgcc ggcagcgaca gcgcgtcggg
    22261 gaagctgacc atatgcgttt cgacgcacag caccggcttg cctgacagtt cggtgatctt
    22321 cagcgcctgt tcgtgctcgc tctcgatgaa caggatggca tcggacttgc ggtagaaatc
    22381 ggccttgaaa ctgccatgcg cgccgagtcg ttgccgttcc gccttgctcg gcagatcgag
    22441 catgatcagc tggtcgtatt tgatctcatg cttggcgagc catgcctcgg tgagcgcgcg
    22501 gtatttctcc agccggctgg tgaccagcca gccgatcctg tgagtcgcga catggagcgg
    22561 ccgcgcttcg ctgaggaatt tctcataggc cgggccgtcg tcgttttccg cctctgtcgg
    22621 gtcgaggcac agcacgccgt caatgtcgac gcagcattgc gccaggaatt tgtgatgcat
    22681 gaagttccac tggaacatgc gcggatgcgg cacgacctcg aagacgaggt cggtttcctg
    22741 gtgcaggggc tcaaggccga acacggcggc aaaggtgaag t
//
