LOCUS       NZ_AZUV01000009        21521 bp    DNA     linear   CON 04-JUN-2024
DEFINITION  Mesorhizobium sp. WSM1293 MesloDRAFT_scaffold_6.7_C, whole genome
            shotgun sequence.
ACCESSION   NZ_AZUV01000009
VERSION     NZ_AZUV01000009.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Mesorhizobium sp. WSM1293
  ORGANISM  Mesorhizobium sp. WSM1293
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Phyllobacteriaceae; Mesorhizobium.
REFERENCE   1  (bases 1 to 350405)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly                          :: ALLPATHS v. R37654
            country                           :: Greece
            environment :: Host; Plant root; Root nodule; Soil
            investigation_type                :: bacteria_archaea
            lat_lon                           :: 37.147182 24.514618
            project_name                      :: Mesorhizobium loti WSM1293
            sequencing_meth                   :: WGS
            biotic_relationship               :: Symbiotic
            rel_to_oxygen                     :: Aerobe
            finishing_strategy                :: Level 1: Standard Draft
            GOLD Stamp ID                     :: Gi08882
            Current Finishing Status          :: Level 1: Standard Draft
            Type Strain                       :: No
            Funding Program                   :: DOE-DD 2010
            Isolation Site :: Serifos, towards Hora from beach
            Host Name                         :: Lotus sp.
            Cell Shape                        :: Rod-shaped
            Motility                          :: Motile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28
            pH                                :: 5-8
            Gram Staining                     :: Gram-
            Symbiotic Relationship            :: Mutualistic
            Diseases                          :: None
            Phenotypes                        :: Non-Pathogen
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method                   :: ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: 454-GS-FLX-Titanium; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000513875.1-RS_2024_06_04
            Annotation Date                   :: 06/04/2024 01:41:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,732
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,524
            CDSs (with protein)               :: 6,524
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 76 of 144
            Pseudo Genes (incomplete)         :: 111 of 144
            Pseudo Genes (internal stop)      :: 9 of 144
            Pseudo Genes (multiple problems)  :: 45 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:13:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 14784
            Orig. end                         :: 36305
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AZUV01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..21521
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="1"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..21521
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21521
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11521](-)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11521)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     misc_feature    550..561
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.73"
                     /tool="antismash"
     gene            <1154..>1897
                     /locus_tag="M729_RS1000000139840"
                     /pseudo=""
     CDS             1154..>1897
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011982997.1"
                     /locus_tag="M729_RS1000000139840"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /product="Tn3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLLISPTENEADPMCSMGHSITVLDIQKTLLIRAVRVITSSGCSL
                     ICNRFAPRRPKKIGSSTCSRRAMLSGAVEPHRGAD"
     gene            complement(2026..2538)
                     /locus_tag="M729_RS0111865"
     CDS             complement(2026..2538)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006329067.1"
                     /locus_tag="M729_RS0111865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF192 domain-containing protein"
                     /protein_id="WP_027161674.1"
                     /transl_table=11
                     /translation="MTHRNWLTTGAICAAIAFVVATGAFFHSQQPASADSRAMIVAVDP
                     QPLVVVTKGGGRSFSVEIADTSAERDAGLMFRDEMADDHGMLFVFEEPRDVSFWMKNTP
                     VPLDLIFVGQDGRIRAIKQGKPQSEAMISPSEPARFVLELKEGTAARSGIADGDLLRHP
                     AIGTAPN"
     misc_feature    complement(2527..2545)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.73"
                     /tool="antismash"
     gene            complement(2672..7438)
                     /locus_tag="M729_RS0111870"
     CDS             complement(2672..7438)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013533569.1"
                     /locus_tag="M729_RS0111870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="shikimate kinase"
                     /protein_id="WP_245267559.1"
                     /transl_table=11
                     /translation="MANLVNGFGKWPEEEKARKAIVAIAGELGSKGRRFRTFSTPALVR
                     IANGLSRCIEEGETAGEAAEPALLKDRLHQLARYLQHAEDRLQQADVHAIASIFKALGK
                     AQLLDDLGVLTQPGLDRLEVLRAAPGFKLDNNLETMGNLCASLLPLARSPKPVLRWHRR
                     SALNLLNAIQPVVEHKIDAHLKAGQAERTSGANASRCPALSIHEVLKTRAVLENLYRLP
                     YVEGDTLALKRRRQELHGKTRQILKSARTLIDAGRSYRSWNVIAEIEAKEPLEALDTFM
                     AQNASMIQAQHAAASFDVHRVLQAMDQEPRPPQGDAGLMRLPVVDMQGRPLASEAELRY
                     STFHRLTSGAVKVVAVQLKGTPTAAMLTRTVAVEGVPYRMDLFGGSKLKPPKKSLNQLA
                     SQLPFTAEEAPSGKLLAIPYAETAPGTAFEQLSRDWAPFKEAYYYTQRRGFAAPPGIPD
                     VGPHDYALEGCFKLSLLPDRPAGAVHPFRLEGRDGEIALRPHDGCGFIRASLAERMPSI
                     ARARHDAPERIPAYADKRQSAVPPSALQHYPRSVEVAQETREKALAWLETHQSLTAEEL
                     FRTVTGGHIEGSSAIAVPSSDECLHVPTGKSKTLTRDAGVLVGRSPYDKPNLRPFAADR
                     VRSARDGDRTAAFLDRCVAFQYSFNVAHRSGARLAADDPTFFAKGVLIVVPDEMWPADF
                     AERGVVMSAEDVKCHSHWLEEKDRVKADTALECVGILQATEVIAPGSLVAVPSAEQKML
                     DGDFDGDSVVIIGDHPRLYEHVRQFDAQLQARGIASMKPPKSHTPAIEKGGYQFSRSKQ
                     ILSTTGLVLETYSCLQRNLLAQPLEAQRWFAERAIFGTYEGIHQELKADIRALLQEDRP
                     DGQTLHELIARAGEDSKAARHPVACELAALLVAELQDWNLQLNSEPAHEQSDVKQQLAR
                     SVASTGANPAVSADAGALFPKLRESYPATADARKRIDFLLNHYQPRIDPRPDGYNPHDL
                     HESALNLLSVGIKVGTDAYKSDTGARVFMQKATELQRLLELRPSFKSAPYVKAQAAKLH
                     QGRFEVDDSLADLKDNPTLAASVMETSIRLAVETRILPSAIAISADDDPASRITLSSEQ
                     ALERARLEAAPAEAQESAITETVHAVAELLRQDGIEVKVPHLDQRSRGHVWIADELTGQ
                     SVSAAPEAQLVTNAVRHIFEIPDETFTRAFRKAALAFEERDCSEVETTNWFIRMDTPRL
                     RGVHTAFRTAQNYRFEVEFHTPASYRADLAQRAQSECEMVPIPRGAWEILHWGSSAESR
                     SRAAGTSRSLTVARQQIALARSPQAGEIVAALGTRPVVLVGMPASGKSSIGPQLAKELG
                     VEFVDIDKLIVKRHGNIADIFKRSGELCFRELEARELAEQLKKGPMVIATGGGGFVKQH
                     NRELIREKAVSIWLNTDLQEIGRRLRGDTSRPLLQGPDKQQQLENMLEERRPDYQQADI
                     RVVPPFKKDKKNAGTCVKELYAFLCSREREAALTPAAEISDVSGASGSAIDLPPTAQRM
                     RDDHDNRYDRGGGVVETIQALAAPMSEGELPPPRDTLTADPQSLLAGNNPRADLASSTR
                     SRERSSPGR"
     misc_feature    complement(7795..7804)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    8109..8124
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            complement(8150..8470)
                     /gene="trxA"
                     /locus_tag="M729_RS0111875"
     CDS             complement(8150..8470)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003589503.1"
                     /locus_tag="M729_RS0111875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioredoxin"
                     /protein_id="WP_027161676.1"
                     /transl_table=11
                     /translation="MATVKVDINNFRSEVLESAAPVVVDFWAEWCDPCKMIAPSLEEIS
                     VEMEDKIKIAKLNIDENSELAAQLGVRSIPALAIFKGGEVADFSVGAKPKIALLNWISN
                     AG"
     misc_feature    complement(8446..8460)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.07"
                     /tool="antismash"
     misc_feature    8605..8619
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            <8706..>8858
                     /locus_tag="M729_RS01000000134865"
                     /pseudo=""
     CDS             8706..>8858
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1281: IS407A,
                     transposase OrfA"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611472.1"
                     /locus_tag="M729_RS01000000134865"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGLARKHGISEATTYSWKAKFRRMDVSEAKRLRHWEEENAKLKKF
                     LAEQML"
     gene            complement(10001..11521)
                     /locus_tag="M729_RS0111885"
     CDS             complement(10001..11521)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: PoyD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Proteusin_Epimerase_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010913536.1"
                     /locus_tag="M729_RS0111885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM family RiPP maturation amino acid
                     epimerase"
                     /protein_id="WP_156949284.1"
                     /sec_met_domain="PoyD (E-value: 3.3e-114, bitscore: 376.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Proteusin_Epimerase_RRE (E-value: 2.9e-20,
                     bitscore: 66.5, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAELVSEEIMSSVGQGAAATAHLYHRSERWRQIFNRRTPKERRS
                     LSHIKRFMERLAGDGKFRKALSENLDNPRIVTACYGIEVDPMEILPLWCGDYLKYRFKP
                     ESAPWPLAMMWDEYTREMLRYRDLMRGQGEMSTNNPRFHVWRERQIRRCNDEMGELAPS
                     ISHSVIAFELSEGCTVGCWFCGLSASTFKGYYEYTEQHAEVWRGVLRVASEMFGSAVRT
                     GFCYWATDPIDNPEYDRFLFDYHQITGELPQTTTAAPLKDQALTKRVLELFERYGRVTN
                     RFSVLSTDHLNQIHAAFSPEDLMGVELILQGEDGPIAKAFTGRARARKEKLRASGKDAA
                     IAVPEGCPTTIACVSGFLVNMRQGRLQLVTPVPGSERWPLGYRIVAQRFFSTPDEFREG
                     LDSIIDENMLESPPPNRPIRFRGDLQYEVGDHCFHLRSRNIEHRVLDGEVPIPIGHLIA
                     IGSCTASELIMRATDGASVLAVADLLDQLYAAGVIEEDLDDVSLGRTG"
     aSDomain        complement(10016..10294)
                     /aSDomain="Proteusin_Epimerase_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing epimerase in a proteusin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M729_RS0111885_Proteusin_Epimerase_RR
                     E.1"
                     /evalue="2.70E-21"
                     /identifier="RREFam010.1"
                     /label="M729_RS0111885"
                     /locus_tag="M729_RS0111885"
                     /protein_end="502"
                     /protein_start="409"
                     /score="66.5"
                     /tool="antismash"
                     /translation="ESPPPNRPIRFRGDLQYEVGDHCFHLRSRNIEHRVLDGEVPIPIG
                     HLIAIGSCTASELIMRATDGASVLAVADLLDQLYAAGVIEEDLDDVSL"
     gene            complement(11563..11937)
                     /locus_tag="M729_RS0111890"
     CDS             complement(11563..11937)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M729_RS0111890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_027161678.1"
                     /transl_table=11
                     /translation="MARTDVERFINELGKKGSPLENLKRRAGGLASIVEVAKDLDYNIT
                     LDEIKGFIRSNRREKPNSKKFRATAGRKGGSSVSTLTSLVHTNAANCAPCTSMSPVEVG
                     GKTAVVAVVIVIVIVVAVAS"
     gene            12712..12951
                     /locus_tag="M729_RS1000000138365"
     CDS             12712..12951
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M729_RS1000000138365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156949285.1"
                     /transl_table=11
                     /translation="MQHQEHRPNSLGMLRNLAIGSAALGDYPVERYGLSESGFADRKHR
                     ISHLDRRFESSPHGERSPGFNEHRHPTILFTKSI"
     gene            complement(13272..>13643)
                     /locus_tag="M729_RS01000000134875"
                     /pseudo=""
     CDS             complement(13272..>13643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009453051.1"
                     /locus_tag="M729_RS01000000134875"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DDE-type integrase/transposase/recombinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RRNTKAAKRLLTRLLKKQGVAPKRMITDKLRSYGAARRQVMPDVE
                     HWSHKRLNNRAENSHVPLRKRGADYARLPITRSTATLGFDLLGSAQSLRPPRSKRSALA
                     THIHRLQAMGEWKAVAMVS"
     gene            complement(13758..15443)
                     /locus_tag="M729_RS0111910"
     CDS             complement(13758..15443)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019859983.1"
                     /locus_tag="M729_RS0111910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_032808328.1"
                     /transl_table=11
                     /translation="MLNNTIARNSLPSIDLLYDYGPFLRLSESEGGIGSFAQNSRRPRV
                     GIVGAGISGLVAATELLRAGITDIVLFEARDRMGGRAWSQIFDPREPHLIAEMGAMRFP
                     SSATCLFHYLDKLRIDTAASFPDPGIVDTEVHYRGARHLWQAGESPPPLFRRVHQGWQA
                     LISDGYVHEGIQLPAPAKITTLLRSHRFDQARDAWQAWLDSFRDISFYSALVTIFTGPQ
                     PPGRVPWKRPEDFELFGSLGIGSGGFLPVYQAAFTEILRLVINGYEDDQRLIMGGISLL
                     VKRLAEQELNGVSLRQCVRYGHVNRIYKQGGQILVTCAGGQVVPFDRVIVTTSNRAMEL
                     AHRLTADGTFLTNEVLRAVRETHLTGSSKLFMLTENKFWLKKGSPTTILSDGLARGVYC
                     LDYQPDDPDGRGVVLLSYTWEDDANKMLSILDKKERCQRLVDDLATISPDFARHLVPAN
                     GDYERHVLQHDWLMDPYSVGAFKLNYPGEDIYSERLFFQFATAKRPEEDTGLYLAGCGC
                     SFTGGWVEGAVQTGLNAACAVIRSSGGQLLSGNPIDSMVSAYRY"
     misc_feature    15605..15621
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 20.08"
                     /tool="antismash"
     misc_feature    15823..15836
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.0"
                     /tool="antismash"
     gene            complement(15872..>16081)
                     /locus_tag="M729_RS01000000134880"
                     /pseudo=""
     CDS             complement(15872..>16081)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012553005.1"
                     /locus_tag="M729_RS01000000134880"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ITILPLPPKSPELNPVENLWLVLRENWLSNRIFKSYDDIVAHCCD
                     AWRKLENQPWRIMSIGRRERTNGF"
     gene            16423..16967
                     /locus_tag="M729_RS01000000134885"
                     /pseudo=""
     CDS             16423..16967
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007603365.1"
                     /locus_tag="M729_RS01000000134885"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="recombinase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRIGYARASTTDQNLAGQIAALKAAGCEVIREEQKSGSTLEGRP
                     QLNTILDFIHAGETLVVTRIDRLARSLRDLQMIVDKLKTKGAHLSATEQPVDTSTPPVR
                     PSLTCLVSLPSSRPICGASAKRRESLPPRSAAHTRAARRKSTATRSSKGLNRVRTQHRS
                     PAISASHAVLSIR"
     gene            17119..17388
                     /locus_tag="M729_RS01000000134890"
     CDS             17119..17388
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M729_RS01000000134890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_245267560.1"
                     /transl_table=11
                     /translation="MFRVSIPASDGTAFNLEKDRFEFLAEQFGLAPSDFGREFRTGSER
                     FRITGIDPKRPRYPISAERIPDRRGFKFAAENVAMLLQAKENKP"
     gene            complement(17674..18342)
                     /locus_tag="M729_RS01000000134895"
     CDS             complement(17674..18342)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1242: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033542.1"
                     /locus_tag="M729_RS01000000134895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS110 family transposase"
                     /protein_id="WP_032808330.1"
                     /transl_table=11
                     /translation="MVLKTRDLLIRQRTQAINALRAHLAELGIVRATGLVGIISLAAMV
                     RDDSDLRLPGAARMALKELVEQIETVTARIERLDRIILAVREDDSARRLTAIPGVGPII
                     AATVRAVVPDFAGFRTGRDFAAWIGLTPRAHSSGGKERIGSISKRGNRQLRTLLVAGAT
                     SILKLARRGLQPSPWIAAMMLRRLFKVIAVALANKIARIIWALLVRGDSYRGAKMIVQA
                     "
     gene            18418..19116
                     /locus_tag="M729_RS0111935"
     CDS             18418..19116
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009453084.1"
                     /locus_tag="M729_RS0111935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS6 family transposase"
                     /protein_id="WP_027161682.1"
                     /transl_table=11
                     /translation="MFKGRQFDESVILVCVRWYLAYNLSLRDLEEMMAERGITVDHTTI
                     HRWAVRFSPLLLEGFNRRKRAVTGKWHVDETYIKVRGQWTYLYRAIDTVGDTVEFWFSE
                     QRDLPAAKRFFRKALERHGRPDRVVIDGSQTNHEAIVCCDITNRLQDRSRRRLKPFRIR
                     RSQYLNNRIEQDHRRIKRRVRPMFGFKSTATACTILSGIEMIPSMGKRQARYAFNPNLS
                     LAEQFEILAA"
     gene            complement(19144..19311)
                     /locus_tag="M729_RS1000000138795"
     CDS             complement(19144..19311)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M729_RS1000000138795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_198032088.1"
                     /transl_table=11
                     /translation="MPAYDANDVYLLDGQAMVACIAGIVSPSCSTGGTHATENESYRRI
                     ALNGFVATAE"
     misc_feature    complement(20220..20235)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.26"
                     /tool="antismash"
     misc_feature    complement(20688..20702)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    21108..21127
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 22.35"
                     /tool="antismash"
ORIGIN
        1 aaccacaagc aggataccgt agcggtgaca gcaatcctgg atcacatccc gcaaatccgc
       61 ctctatcgga accaggccca cgcgggaagc aactggatcg aaaaggatcg cggcgagacg
      121 ctcatggtgt ttacggatga gctctctgca cgacttgggc tcgttgtaag gaaggacaag
      181 gacatccgcg gcggtggagg ggggagttcc actggcgtag agcacactgt taggcgacga
      241 attgccccag ttgtttggtg cagaatcaag gctcacttcc acatagtcat aggcgccgtg
      301 atatgcgccc tcgaacttgg caatcatagg gcgccctgta acagcgcgag cggccttgac
      361 agcgaagatg acggcctcgg tgccggaact cgtaaagcgg acctgctcaa gcttcgacga
      421 acgcgtcgtg agtgcttccg caagcctggt ctcgcttgtg gtcgggagcc cgaatgcggt
      481 cccgtcgtcc aggaccttgt gcagcgcctc aatcaccggc ggaaaggcat ggccgtgaac
      541 gagcgagaag aaattgtttt cgcagtcgaa gatcttcctg ccgtccgcgt cggtgatcca
      601 gcagcccgct cctgacacag catagggcgg gtgtggagcg aagaaaggcg cagcacgcat
      661 gcttccgcct ggcgtgatct ttagcgaacg ctgaaactcg tcgcgcgatc tcggcccaac
      721 aacctctccc cggttgtggc ccagccttga aatgcgcttc atgtccgaac tccttgacct
      781 gtcgagatgg cgaggcgcta cgaaaccttg atgccattgt tgtcgtcggc gacttggagg
      841 aagcgtgaga tgctcaatgg attaactaag cctttgtcat cgcagcttgc ccgatcgtgg
      901 tgattgggcc gtgggggtgg acggcgaggc ttcatatgga tggctacacc atcaacacgg
      961 atcgggatgc ttcccaagtc agctccaaca agaagaaggc caacgagacg gctttcaatg
     1021 agtctatgtc gttagcatgg gcggcggttt ggagttgcta agagtctatc aatttctttg
     1081 aaggatctgt tacactgctt gccgccgacg gctcaaccga actgttcgca gaccatcctg
     1141 ccttgttgcg cccattctgc tcatcagtcc gaccgaaaac gaggcggacc ctatgtgctc
     1201 gatgggccat tcgatcacgg tcctcgatat ccagaagact ttactgatac gggcggtgcg
     1261 agtgatcacg tcttcgggct gttcgctgat ctgcaatcgg ttcgcaccgc gacgcccaaa
     1321 aaagatcgga agttccacat gttcgagaag ggcgatgcta tccggcgctg tcgaaccaca
     1381 tcggggcgcc gattaacacc actctgattc tccaccaatg ggacgatctg ctccatctgg
     1441 cggcgtcgat cacaacgcgg tccgtggtgc gtctacgatc ctgaggaacc tgtccgcgtc
     1501 cagctcgcaa gggcgctacg ggaactcgat aagatcgagc gctcgctctt cacacgagtg
     1561 atactcaagt ccgatgttgc gtcggcgctg ccaagctggg ctcagcaagg cgaagctgcg
     1621 cataaactga agggcgccgt cttgttccac gagcgcggtg aaatccgcga ccgatcattc
     1681 gaaagccagg ccttgcgcgc ctccgggcct cgttagtgcg atcgtgaatt ggaacgcggt
     1741 ctatatcgaa cgggccgtca cccacttgcg agaatgcacc ccgagactct ggatgttgcc
     1801 caatcacgtc tcgccgctga gctcggaaca aatcaatctg accggaatct acacctggga
     1861 tacagaacat gaggtacctg aaggcttccg atcgctcgac cccgactcgg ttacgccacg
     1921 ccgcacaacg ttcatgctcc gttcgatctt ggcgtgtcgc tgggaacagt tcttgttccg
     1981 acccgtcatg ggagaaaaac tgcatctgcg atcgatcctg cgcgttcagt tgggtgcagt
     2041 gccgattgcc gggtgacgca acaaatcgcc gtccgcgatg ccgctcctgg ctgccgtgcc
     2101 ttccttgagc tcgagcacga agcgagccgg ctcgctgggc gagatcatcg cctccgattg
     2161 cggcttgcct tgcttgatcg cccggatcct gccgtcctgg ccgacaaaga tcaggtcgag
     2221 cggcaccggc gtgttcttca tccagaagct gacgtcccga ggctcctcga acacgaacag
     2281 catgccatgg tcgtcggcca tctcatcgcg aaacatcagg ccggcgtcgc gctcggccga
     2341 ggtgtcggcg atttcgacgg aaaatgagcg tccgccgcct ttcgtcacca cgaccagcgg
     2401 ctgcgggtcg acggcaacga tcatcgcccg gctgtcggcc gaagccggtt gctgcgaatg
     2461 gaagaaagcg cctgtggcga cgacaaaggc gatcgccgcg caaattgcac ccgttgtcag
     2521 ccagttcctg tgagtcattc gaaatcctcg gccggaatcg tcctacttct gacgacttta
     2581 tgcatgcgat tcccgctttt attagcattc ggcggcgtac ccgcacgctc tgcaccaaac
     2641 ctgcgaaaga acccttgtgc cacttaaagc tttatcgtcc tggacttgag cgttctctgc
     2701 ttctcgtgga agacgctaaa tccgctcgtg ggttgttgcc ggccagcaaa gactgcgggt
     2761 cggcggtgag ggtgtcgcgg ggcggcggca gttcaccttc actcattggt gccgccagcg
     2821 cctggatggt ttccacgacg ccgcccccgc gatcatagcg gttgtcatga tcgtcgcgca
     2881 tgcgctgtgc tgtcggaggc aagtcgatgg cggagccgga agcaccagag acatctgata
     2941 tctcggcagc gggcgtcagg gcggcttctc tctccctgct gcacaggaaa gcgtagagct
     3001 ccttcacgca agtgccggcg ttcttcttgt cttttttaaa gggcgggacc accctgatat
     3061 cggcctgttg gtagtctggc cggcgctctt ctaacatgtt ttcgagctgc tgctgtttgt
     3121 cggggccttg tagcagcggc cggctggtgt cgcccctgag acgcctgccg atctcttgca
     3181 ggtcggtatt gagccagatc gacaccgcct tctcgcggat cagttctcga ttgtgctgct
     3241 tgacaaagcc gccgccgccg gttgcgatga ccatgggccc tttcttcagc tgctcggcga
     3301 gctctctagc ctccagctcc ctgaagcaca gctcgccact gcgcttgaat atatccgcaa
     3361 tattgccgtg ccttttgacg ataagcttat cgatgtcgac aaactccacc cccagctcct
     3421 tggcaagctg ggggccgatg ctcgacttgc cgctcgccgg catgccgacg agcaccaccg
     3481 gccgcgtgcc gagggccgcg acgatctcgc cggcttgcgg cgagcgagcg agcgcaatct
     3541 gttgtcttgc gacggtgagc gacctggagg tacctgccgc cctcgacctg ctttctgctg
     3601 acgagcccca gtgtaatatc tcccaggcac cacggggaat ggggaccatc tcgcattcgc
     3661 tctgcgcgcg ctgcgcgaga tcggcccggt aactggccgg cgtatggaac tcgacctcga
     3721 agcgatagtt ctgcgcggtt ctgaacgccg tgtgcacgcc gcgtaaccgc ggcgtgtcca
     3781 tcctgatgaa ccagttggtg gtctcgacct cgctacagtc ccgctcctcg aaggccagtg
     3841 ccgccttcct gaaggcgcgc gtaaatgtct cgtcggggat ctcgaagata tggcgcacgg
     3901 cattggtgac cagttgggcc tccggcgccg cgctcacgct ctggccggtc aattcgtcgg
     3961 ctatccagac atgcccgcgc gaccgttggt caagatgcgg caccttcacc tcgatgccgt
     4021 cctgccgcaa aagctcggca accgcatgca cagtttcggt aatcgcgctt tcttgcgctt
     4081 cggcgggggc ggcttcgagc ctggcgcgct ccagggcctg ttcgctgctc agcgttatcc
     4141 tgctggcggg gtcgtcgtcg gccgagattg ctatggcgct gggcagaatg cgggtttcga
     4201 cggcgagtct gatcgaggtc tccatgaccg aggccgccag cgtggggttg tccttcagat
     4261 ccgccaggct gtcatcgacc tcgaaccggc cctggtggag ctttgccgcc tgcgccttga
     4321 catagggcgc cgacttgaag ctcggcctca gctccaatag ccgctgcaat tcggtggctt
     4381 tttgcatgaa cacccgcgca ccggtatcgg acttgtaggc gtccgtgccg accttgatgc
     4441 cgacgctcaa cagattgagg gcgctttcat gcagatcgtg cgggttgtag ccgtcgggtc
     4501 gcggatcaat gcgcggctgg tagtggttga gcaggaagtc gatgcgcttc ctggcgtcag
     4561 cggttgccgg ataggattct cggagtttcg ggaagagcgc gccggcgtcg gcgctgacgg
     4621 caggattcgc gccggttgag gccacggatc gcgctaactg ctgcttgacg tccgactgct
     4681 catgagccgg ctcgctattg agctgcaggt tccaatcctg aagctcggcc accagcaacg
     4741 cggccagttc gcaggccacc ggatgcctgg cggccttgct gtcttccccc gccctggcga
     4801 tcagctcatg gagggtctgg ccatccggcc gatcttcctg caacagtgcg cggatgtcgg
     4861 ccttgagctc ttgatgaatg ccctcgtagg tgccgaagat ggcacgctcg gcaaaccagc
     4921 gttgcgcctc cagcggctgc gccagcagat tgcgctgcag gcagctgtag gtctccagca
     4981 ccagcccggt ggtcgacagg atctgcttgg accggctgaa ctggtagccg cctttctcaa
     5041 tggccggtgt gtgcgacttc ggcggcttca tcgaggcgat gccgcgcgcc tgcagctgcg
     5101 cgtcgaactg gcgcacatgc tcgtaaaggc gagggtggtc gccgatgatg acgacgctgt
     5161 cgccgtcaaa atcgccgtcg agcatttttt gttcggcgct cggaaccgca accaaagagc
     5221 cgggcgcgat cacctccgtc gcctgcagga tgccgacgca ctcgagcgcg gtgtcggcct
     5281 tgacccggtc cttttcctcc agccagtgcg aatggcactt tacgtcctcg gcagacatca
     5341 ccaccccgcg ctcggcgaag tccgccggcc acatttcgtc gggcacaacg atcaagacgc
     5401 ctttggcaaa gaaggtcgga tcgtcggcgg caagcctagc ccccgacctg tgcgcgacgt
     5461 tgaagctgta ttggaaggcc acgcaccgat ccaggaacgc cgcggtccga tcgccatcgc
     5521 gcgccgacct gacccggtcg gcggcgaacg ggcgcaggtt gggcttgtca tagggggagc
     5581 gtccgacaag cacgccagcg tcacgggtca aggtcttgct cttgcccgtc ggcacatgca
     5641 ggcattcgtc gctggacggc acggcgatag cgctcgaacc ctcgatatgc ccgcccgtga
     5701 ccgtccggaa cagctcctcg gcggtgaggc tttgatgggt ttcgagccat gccagagcct
     5761 tctcgcgggt ctcctgtgcc acctcgacgc tgcgcggata atgttgcagc gccgagggcg
     5821 gtaccgccga ttgcctttta tcggcatagg caggtatccg ctcgggagcg tcgtggcgag
     5881 ctcgggcaat ggacggcatg cgctcggcca gcgacgccct gatgaagccg cagccgtcat
     5941 gcggccgcaa ggcgatctcg ccgtctcgcc cctccaaccg gaagggatgc actgcgcctg
     6001 cggggcggtc gggcagaagg gacagcttga agcacccttc cagcgcataa tcatgcgggc
     6061 caacgtcggg gatgcccggc ggcgcagcaa atccgcggcg ctgggtatag taataggctt
     6121 ccttgaacgg cgcccagtcc cgcgacagct gctcaaaggc cgtacccgga gccgtctcgg
     6181 cataggggat cgccaaaagc ttgccgctcg gggcctcttc ggccgtgaag ggcagctgag
     6241 aggcaagctg gttcaggctc tttttcggcg gcttcagttt gctgccgccg aacaggtcca
     6301 tgcggtaggg cacgccctcc acggcgaccg tgcgtgtcag catggcggca gtcggagttc
     6361 cctttagctg caccgccacc accttcaccg cgcccgaggt caagcggtgg aaagtggaat
     6421 agcgcaactc ggcttcgctg gccagcggcc ggccttgcat gtcgaccacc ggcagccgca
     6481 tcagtccggc atcgccttgc ggcggtctcg gctcttggtc catggcctga aggacccgat
     6541 ggacatcgaa gctggcggct gcatgctggg cctggatcat cgatgcgttc tgcgccatga
     6601 aggtgtcgag cgcttcgagc ggctccttcg cctcgatctc ggcgatcacg ttccagcttc
     6661 tgtaggaacg gccggcgtcg atgagggtgc gggcgctctt cagtatctgc ctggtcttgc
     6721 catgcagctc ttgccgcctg cgcttcaagg ctagcgtgtc gccctcgaca tagggcagcc
     6781 ggtagaggtt ctccagcacc gcccgggtct tgagcacctc atggatcgaa agcgccgggc
     6841 agcggcttgc attggcgccg ctggtgcgct cggcctggcc tgctttgaga tgggcatcga
     6901 tcttgtgttc caccaccggc tggatggcgt tgagcaggtt cagcgccgac ctgcggtgcc
     6961 agcgcaacac cggcttcggg ctgcgagcca gtggcagcag ggaggcgcaa agattgccca
     7021 tcgtctcgag gttgttgtcg agcttaaacc cgggagcggc acgtaacacc tcgagcctat
     7081 ccagccccgg ctgtgtcagc accccgagat cgtccaacaa ctgcgccttg cccaacgcct
     7141 tgaatatact cgcgatcgca tggacatcgg cctgctgcag ccgatcctct gcatgctgga
     7201 ggtagcgcgc cagctgatgc aggcggtcct tcagcaaggc cggttcggcg gcctcgccgg
     7261 cggtctctcc ctcctcgata caccgcgaca gaccgttggc gatcctgact agcgcaggcg
     7321 tgctgaaagt cctgaagcga cggcccttgg aaccgagctc gccggcgatg gcaacgatcg
     7381 ccttgcgtgc tttttcttct tccggccact taccgaaacc gttcaccaga ttggccaatt
     7441 cttgatccga gaatccgtcg cgggcaacca ccgcgccggc tatggcaacc gtcgcttctc
     7501 gcgtcttctg ctggtccggc catctgctga agccgttcac caaaccggcc aactctgaat
     7561 ccgaaaatcc gtcgagattg ccgtcgcggg caaccaccgc gccggcgatg gcaagcgtcg
     7621 cttcacgcgt ctcctgctgg tccggccatc ggctgaagcc gttcaccaaa tcggccaact
     7681 ctgaatccga aaatccgtcg agattgccgt cgcgggcgac caacgcgtcg gcgctggcaa
     7741 gcgtcgcctc gcgcgtcttc tgctggtccg acattgcgtc tgagatgcgg tgcgggccgc
     7801 cttcgctatt aggacgccct gcttgtccgg ccaactctcc ggtgctgccc atattccctc
     7861 tccgatccag caaaacgcat cgcctaggcc tgtcaacaac agatcattgg tttgagtgcg
     7921 gtcaggcgag cctgcaacgg catgcttgaa agccgcagca ttcacgcaac gacaactgcc
     7981 tcgacaacac cgcaatgaaa agcttcttgg ccactcgatc gctccgacat caggctgaag
     8041 cttaaagggc tgagccgtgt acaaaacgcc cataaatcac tatggaccct cccgctttgc
     8101 gggccgaatc tacggttttt tcattgcggt acagattgag cgatatcgat cagccagcgt
     8161 tcgaaatcca gttcaaaaga gctatcttcg gtttggcgcc gaccgagaaa tcggccactt
     8221 cgccgccctt gaagatcgcg agcgccggaa tggagcgcac gcctaattgg gcggcgagct
     8281 ccgagttttc atcgatgtta agcttggcga tcttgatctt gtcttccatc tcgacggaga
     8341 tttcctcgag gctcggagca atcatcttgc agggatcgca ccattcggcc cagaaatcga
     8401 cgacgacggg tgctgcggat tccagaactt ccgaccggaa gttattgata tcgactttca
     8461 cggtagccat ggctgctcct ttgaccgaag aagatgttga atcaaatgtg cggttttcgg
     8521 cttagccgaa cgctgtttcc actttgactg agcccgagtg agatgatgta agttttgcga
     8581 gcggcaaatg gaccttcgtt caatatcgaa tgcgtcgatt ggagcgtgtc ctttaatgaa
     8641 gatccaaaat tctgaagcgt caacgtcgaa acgggttaca ttcgtaatgt ggatagatcg
     8701 gacatgctgg actggctcgc aagcatggga tctccgaagc gacgacctac agttggaagg
     8761 ccaaatttcg gcgcatggac gtttccgagg cgaagcggct gaggcattgg gaagaggaga
     8821 acgcgaagct gaagaagttt ctggccgagc agatgcttct acgtggccgc ccttcgcgag
     8881 ctgctttcaa aatgacccgc ccccgtgcaa gggtcgtttc gatcaggacg atgcagtgtt
     8941 ctgctccgat accattcttt ggaccgccgg aaggtagaat ttcccggctt tctcacgatg
     9001 gcgcctgcgg cgacagggcg ggcggcccga tgtaagcgtc ttgccgccca gtcggtctct
     9061 ggtcgtcttc atcattgcgg ttgccgccaa gcgggccgcc gatctgggaa ggagatcggc
     9121 acctcggagg tcgagcggat ctcgacggcg cgtcaaacgg acccgcccca ggcctcgcaa
     9181 cgtcaagctc gtcctatccg cgagaaaccc gacagcgcca ggaacgcgcc cggtgacctc
     9241 gggaattccc atcaattcac cgacgctgcc acgcgccagc ggcccgctga caaaaatgct
     9301 gttggtcgtg cgcccggatg tgccgaccgc atggccttgg ccgtcggttt cgcacgtccc
     9361 ggtggtctgg gcggcttcgc gccttggccg cagtgtgaca cgaatgcgcc cgtcaacccg
     9421 ctcggggccg gtatccgatg cgacgcggca agcgagcgtt cccgcgcaac gcggcaatcg
     9481 agaacggcga ttctgcggcg caatgcggaa gcgatgcaca tcccaaagcg cgcgcaaatg
     9541 gcgcatcacg caagcgttgc tcagcgagcg gcaaggcgtg ccagacagtc tgccctgtcg
     9601 ccggacggca tcgagcaccg ggtgccagtc tgcgccaaga gacttggcat ctcgaatcgt
     9661 tgccgggatg cacttgaagg tgccgtcgcg ctgcgtgaag gagggctcgt gaaatcacca
     9721 aatggagaga tgtcgcggcc tggccgcgcg cacgataacc atgacgtgac agcgcaacgg
     9781 accggggacc agaggatccg tgaggggaac gccacgccgg cctggcttgc caatgattca
     9841 atgccaaccg tcggcataga gcgttcggta agcttggcgc cattgtcctt ggcgaagccg
     9901 tcggcgagca cctcgatgtc gtcgaggacc ggccgcgata gcccgtttta tcggattcga
     9961 acgcagggca aaaaagcccg cggcccgagg cccgcgcccg tcatcccgtt ctaccaagcg
    10021 aaacgtcgtc gaggtcctct tcgatcaccc cagccgcgta aagctgatcg agcaggtcag
    10081 cgactgcaag gacgctcgct ccatccgtgg ccctcataat cagctccgag gctgtacagc
    10141 tcccaatcgc gattagatgg ccaatgggaa tcggaacctc cccgtcgagc actcgatgct
    10201 caatgttgcg tgagcggaga tggaagcagt ggtcccccac ctcgtactgc aggtctccgc
    10261 ggaagcgaat tggccggttg ggaggcgggc tttcgagcat attctcgtcg atgatgctat
    10321 ccagaccttc cctgaattcg tcgggcgtgc tgaagaaacg ttgagccacg attcggtacc
    10381 cgagaggcca gcgttcgctc cccggtaccg gcgtcaccag ttgtaaacgt ccctgccgca
    10441 tattcaccag aaagccagaa acacaggcga tagtggtggg acagccctcc ggcacggcga
    10501 ttgcggcatc tttgccggac gccctgagtt tctccttccg cgcgcgcgcg cgcccggtga
    10561 aagcctttgc gatcggcccg tcctcgccct gcaggatgag ttcgaccccc atcaggtcct
    10621 cgggcgaaaa cgccgcgtgt atctgattaa gatggtccgt gcttagcacc gagaaccgat
    10681 tggtcacgcg accgtagcgt tcaaacagtt cgagcacgcg cttggtgagt gcctgatcct
    10741 tgagcggtgc cgccgtcgtc gtttgtggca attcgcccgt gatttgatgg tagtcgaaca
    10801 gaaaacggtc gtactccggg ttgtcgatcg ggtctgtggc ccagtaacag aagcccgtgc
    10861 ggactgcgga accaaacatt tcgctcgcca cacggagcac gccgcgccaa acctctgcat
    10921 gctgctcagt gtattcatag taacctttga aggtacttgc cgagaggcca cagaaccagc
    10981 aaccgacggt gcagccttcg ctcagctcga aagcgatgac ggagtgcgag atcgacggcg
    11041 ccaattcgcc catttcgtcg ttacagcgcc ggatttggcg ttcgcgccag acatgaaagc
    11101 gaggattgtt agtggacatt tcgccttggc cgcgcatgag gtcgcgatag cgtaacatct
    11161 cccgcgtata ctcatcccac atcatagcca gcggccaggg ggcagactcc ggcttgaagc
    11221 gatacttcag gtagtcaccg caccagagcg gcaggatctc cattgggtca acttcgatgc
    11281 cgtagcacgc ggtcactatc cgagggttgt cgaggttctc ggaaagcgcc ttacggaatt
    11341 tcccgtcacc ggccagccgc tccatgaagc gcttgatatg tgacaaactt cgccgttcct
    11401 tcggcgtgcg ccgattaaaa atctgccgcc agcgttcgct ccgatggtag agatgagccg
    11461 ttgcagcggc cccttgtccg actgatgaca ttatctcctc gctgacaagc tctgcgatca
    11521 tgttctcttc ataccggctc catcgagcca atgcgatcag agctagctcg cgaccgctac
    11581 aactatcaca atgacgataa cgaccgcgac gactgcagtt tttcctccga cttcaacagg
    11641 gctcatggat gtacacggag cgcaattagc cgcattggtg tgtacaaggc tggtcaaggt
    11701 cgaaacactc gaaccaccct tgcggcccgc agtcgcgcga aacttcttgc tgtttggttt
    11761 ttctcgcctg ttcgatcgga taaagccttt aatctcgtca agtgtgatgt tgtagtcgag
    11821 gtcctttgca acttccacaa tcgacgcaag ccctccagca cgccgtttga ggttttcaag
    11881 cggactgcct ttttttccca actcgttgat gaatcgctct acgtcagttc gcgccatagc
    11941 taattcctgc ctctcctaag tgtccgagct atccagccat ctcgctctcc acaagcgatc
    12001 ggctgatgta cctgcaagct tcatacgctg atgtaccagc aagcttcata ccaatctcca
    12061 atctctgatt ttgcgcgcta tctgaccgca cgatgtcaac ttaccgacct ttttctggat
    12121 ctttcggatc gtggccgagt agctgagcca ttcggctttt cgccttaaaa catccgggcg
    12181 ggtggattcc cacaccattg tggccggctg tattggtgcg ggaaagccgc gcatgccgag
    12241 ctggcgcgct gtcgctgccg catgacatga cacgaagcgt ggtctcgctg ccaacgccat
    12301 tggtaacggc agcgcagttc tggaggaggt ggcaaagggc gcgaagcgag gtgttctcac
    12361 cttagataac aatcgcttcg taggcgtcgg ctctccggcg ccgatcctta tgcagtcctc
    12421 ccgcgtcggc tgcccgatct cgaaacgcat gccgatacgg ctttcgatct ggtccacagc
    12481 gcgggtatca cgcctcgtgc ccgctaaccg atgagtgttg ccggcgagca gtaaagcgaa
    12541 gccgcacctc tcctgaagat ggagcagctc ccgcaaaaca gtgggtgtga agttctaata
    12601 ttcgtccacc agcaagggac gcgtcgggcc gtatcgggcg ccaaaaaaat tcatgcaatc
    12661 cttcgcaaga tcatatgtgt gcttgctgtc ccttgggacg ccataggcct catgcagcat
    12721 caggaacatc ggcctaatag cctcggtatg ctgcgcaacc tcgcaatagg cagcgccgct
    12781 ttgggcgact atccagttga gcgctacggt ctttccgagt ccggctttgc cgaccgcaag
    12841 caccggatat cgcatcttga ccgccgtttc gaaagcagcc cgcacggtga gcgcagcccg
    12901 ggttttaacg aacatcgtca tccgacgatc ctcttcacca agtccatctg agcggctatg
    12961 cgctcgtcct gttcgcgtcg gcgctcttcg gagatcaaag gcttcttcgg catcacgatc
    13021 cgcgccggcc gctgagacag gttccccctc gcggtcccat tcgtagtccg actcctgtca
    13081 ttctgcattg catactgcat tgacgtcggc tcgtcggagg tgcggtcgta atacagctcg
    13141 aataccgttg cgaggtggtc agaaagttct ttaaggctga agctgggatc ttcgtcccgg
    13201 caatagaaac attgcgaggg ggatgtcacg ttgtctgcat atacacgcgt cgagacctgc
    13261 agccgctgat gtcagctgac catggccacg gctttccatt cccccatggc ctgcaggcgg
    13321 tgaatatgtg tagcgagagc ggagcgtttt gagcggggcg gacgaagaga ttgcgcagag
    13381 ccgagaagat cgaaaccaag cgttgcagtg ctcctggtga tcggaagcct tgcataatcc
    13441 gctccccgtt ttcgcagcgg cacatgcgaa ttctcggcac ggttgttcaa tctcttatgc
    13501 gaccaatgct cgacgtccgg catcacctgt cgcctggctg ctccatagga gcgcagcttg
    13561 tcggtgatca tgcgcttcgg cgcgacgcct tgcttcttca gcagccgcgt cagcaagcgc
    13621 ttggccgctt tagtgttgcg gcggttccag tccaacgccg aagttttccc ggccagtatt
    13681 tgattgcaaa tctccttgag tgtggacgtt tcaaatattt aagaagcctt ttctaaagaa
    13741 ggctaattta ccggttctca atatcgataa gcggaaacca tcgaatcaat agggttaccg
    13801 ctcaagagct ggccgccact gctgcggata acagcacatg cggcattcaa gcccgtttgt
    13861 accgcgccct cgacccaccc gccggtaaag gagcatccac atcctgcgag atacaagccc
    13921 gtgtcttctt ccggtctttt tgcggtagcg aattggaaaa ataaccgttc tgaatagatg
    13981 tcttcaccag gataattgag cttgaaggca cctactgaat atggatccat cagccaatcg
    14041 tgctgcagga catgacgttc atagtcaccg ttagccggga ctagatgacg ggcgaaatca
    14101 ggggaaatgg tggccagatc atcgaccaga cgctggcacc gttccttttt gtccagaatg
    14161 gaaagcattt tgttagcatc atcttcccat gtataactta acagcaccac gcccctacca
    14221 tcgggatcat ctggctgata gtccaggcag taaacccctc tggcaaggcc atctgacaag
    14281 atggttgtcg gcgagccctt ttttaaccag aacttgtttt ccgtcagcat aaacagcttg
    14341 gaagagccgg taaggtgagt ttctctgacc gctcgcaaaa cttcgttagt aagaaaggtt
    14401 ccatccgccg tgagacgatg ggccagttcc atagctcgat tgctggtagt gacgatgacg
    14461 cggtcaaaag gcacgacctg ccctcctgcg catgtcacga gaatctgacc gccctgtttg
    14521 taaatacggt ttacatgacc gtagcggaca cactgccgca aactcacacc gttaagctcc
    14581 tgttcagcca accgtttcac caacagggag atcccaccca taatcaggcg ctgatcgtcc
    14641 tcgtacccgt taattactag acgcagtatc tcagtaaacg cggcttggta cacaggtaaa
    14701 aagcctccag acccaatccc cagcgatccg aaaagctcaa aatcttccgg ccttttccaa
    14761 ggtacgcgcc ctggtggttg cggtccggta aagatggtga cgagggccga atagaaggag
    14821 atgtcgcgaa acgaatctag ccaggcctgc catgcgtcac gagcttggtc aaagcgatgc
    14881 gaccgaagca aagttgtgat ctttgccggt gcgggcagtt gaatcccttc gtgcacgtaa
    14941 ccgtcgctta tcaaagcctg ccatccttga tgaacgcgtc tgaacagtgg cggcggagac
    15001 tcgccggcct gccataaatg acgcgcacct cgatagtgca cctcggtatc cacgatgccc
    15061 ggatcgggga aggaagctgc ggtatctatc ctcaatttgt ccagataatg gaacaggcag
    15121 gttgcgctgg aaggaaagcg catagcgccc atctcggcaa tgagatgcgg ttcgcgcggg
    15181 tcgaagattt gtgaccaagc ccgcccaccc atacgatccc gcgcctcaaa tagcacgatg
    15241 tccgttattc cggcgcgcaa aagttcagtc gccgcaacca agccactgat gccggcgccc
    15301 acaatgccaa cccgcgggcg ccggctgttt tgagcaaagc tcccgatacc accttcagac
    15361 tcgctcaatc gcaagaacgg tccataatca tacagaagat cgatactcgg caacgaattt
    15421 cttgcgatgg tattgttcag cataccgctc tccggtgata gctatatttc ttgagatcta
    15481 gtgtagccgc cctcagaatg cctcccctgt taaattggaa cgctggccac agcataacaa
    15541 ttgctgctca ccggaggcgc aattaacggt acgtattaga agagaccttg ccagctttag
    15601 tacttagtaa taaaagaact tcaaacacat atcactaatc gacgattgac gcatatttat
    15661 ttggatgaga atggattagc cgaaatacat cgcgttcctc tcatatgggg aagtctcgct
    15721 cctgccacca acatgctcca aatactcttg cgcgatatct tctattagtg cttgctaact
    15781 atcaatatta tctatttctt tctatcacta aattcccacc cattgaatta ttattacgtt
    15841 tcatatgtaa tataatacgc ttccttactg atcagaaccc atttgtcctt tctcttcggc
    15901 cgatggacat gatgcgccaa ggctggtttt cgagcttgcg ccaagcatcg cagcaatggg
    15961 cgacgatatc gtcataggat ttgaagatgc ggttcgacag ccagttttcg cgcaatacga
    16021 gccagaggtt ttcgaccggg ttgagctccg gtgatttcgg cggcagtggc aggatggtga
    16081 ttcgtaggca cgacgcctgg cgtcttttcc ggcaagcagc ctttggttgc ttccatcggc
    16141 ggctatatca ctttgggggg cgaggatgag gcagctgact acgtcgacga aaacggccag
    16201 gcatggcagg ccacgcccgg tgcagtcgcg tggctggcgg aggttaccag aaagctgaaa
    16261 ccccgacgac ggcgtaactg accaccggaa ccgatggggg tatacccggc ctgaacaccc
    16321 gccatgaaca cgtcgcaacc ggaaaagcct gtatatattt tgggctcaat cttcgttaat
    16381 gaacagagca tcgcgccggc acacccaaaa tgaacagttt gcatgacccg catcggatac
    16441 gctcgcgcct ccaccaccga ccagaacctc gccgggcaga tcgccgcgct caaggccgcc
    16501 ggctgcgagg tcattcgcga ggagcagaag agcggctcta ccctggaagg ccgtccgcaa
    16561 ctcaacacca ttctcgactt cattcatgct ggcgagacgc ttgtcgtcac ccggattgac
    16621 cgcctggcca gatcgctgcg cgacctgcag atgatcgtgg acaagctcaa gacgaagggc
    16681 gcgcatctct ccgcgacaga acaacctgtc gatacgtcga cgccgccggt aaggccttct
    16741 ttgacatgct tggtgtcttt gccgagttcg agaccaatct gcggcgcgag cgccaagcgg
    16801 agggaatcgc tgccgccaag aagcgcggca catacaaggg ccgcccgccg aaaatcgacc
    16861 gcgacgcgat ccagcaaagg cttaaacagg gtcaggaccc aacacagatc gcccgcgatc
    16921 tcggcgtctc acgcggtact gtctatcagg tgaggaaggg caaatgatga agggcaggct
    16981 cataacccgt ctgacgccac atgcgaagag atccagaccc gcatgctcga agtctgccag
    17041 aagatcgctg aggaccatgg cctggtcatc tagggcgccg gatggcacgg tacggatacc
    17101 ggcttcttct tcgagcccgt gttccgcgtc agcattcccg cttccgacgg caccgcattc
    17161 aatctcgaaa aagacaggtt cgagttcttg gcagagcaat tcggattggc cccttcggac
    17221 ttcggacgcg agttccgcac cggaagcgaa cggttccgga tcaccggcat cgatccaaag
    17281 cggccacgct acccgatctc cgctgagcga attcccgacc gcagagggtt caaatttgcc
    17341 gccgaaaacg tcgccatgct cctccaagcc aaggagaaca agccgtgacg ttctcggatt
    17401 gttagccaaa atcgcatata tggaacggcc cgcttggcat atttcctcat gtatttcccc
    17461 agtaaggacg gtgcggtcat atgtccggcc tgttttctgg cctttcagcc atggccacga
    17521 tgagatccgc ggagcaaatc gcctaatcag cttctcgcgc tgtaacgcgc ttgcgatttt
    17581 gcggtcagat ttgcttcggg atgtcgtccc gttggctcat cacaattggc accttgcctg
    17641 cctttccgac tggtaggccg gaaagcgcgt tgtctaagcc tggacgatca tcttcgctcc
    17701 ccgatagcta tcgcctcgaa cgagaagagc ccagatgatg cgcgcgatct tgtttgcgag
    17761 tgcgacagcg ataaccttga acaggcggcg caacatcatg gccgctatcc atggtgatgg
    17821 ctggaggcca cgacgagcga gcttgaggat cgacgtcgct ccagcgacaa gcaacgttcg
    17881 cagttgccgg tttccgcgct ttgagatcga acctatccgt tcttttcctc cgctggaatg
    17941 cgcgcgtgga gtcaacccaa tccaggcagc gaaatctcga ccggttcgga agccagcgaa
    18001 atccggtaca actgctcgaa cggtcgcggc aatgatcggc cccacgccgg gaatcgccgt
    18061 caggcgtcga gcgctgtcgt cttctctcac cgcaaggatt attcgatcga gcctttcaat
    18121 gcgtgccgtc acggtctcga tttgctcgac tagctctttc aaagccattc gtgctgcacc
    18181 cggcaatctc aggtcactgt cgtcgcgcac catggcggca agactgatga ttccgaccag
    18241 accggtcgcc ctgacaatgc ccagttcggc aaggtgagct ctcaaggcat tgattgcttg
    18301 agtgcgctga cggatgagca aatctcgtgt tttgagcacc attctgggag gttctgttgc
    18361 aaccttttga ttgccagcgc tgtggcaagg agccttcgat catttcgaag ggttgcaatg
    18421 ttcaaaggcc gtcagttcga cgaatccgtg atcctggtgt gcgtgcgctg gtatctcgcc
    18481 tacaatctga gcctgcgcga tcttgaggag atgatggccg agcgcggcat cacggtcgat
    18541 cacacgacca tccaccgctg ggccgttcgt ttctcgccct tgttgctcga gggtttcaac
    18601 cggcgcaagc gtgccgtcac cggcaagtgg catgtcgacg agacctacat caaggtccgc
    18661 ggccagtgga cgtatctcta tcgcgccatc gacactgtcg gtgacacagt cgagttttgg
    18721 ttcagcgagc agcgcgacct gcctgcggcc aagcgcttct tcagaaaggc gcttgagcgt
    18781 catggccgac cggatcgcgt cgtcatcgac gggagccaga ccaaccacga ggcgatcgtt
    18841 tgctgcgaca tcacaaatcg cttgcaggat cgctcccggc gccggctgaa gccgttccgc
    18901 atccgccgga gccagtattt gaacaatcgg atcgagcagg accatcggcg tatcaagcgg
    18961 cgggtccggc cgatgttcgg cttcaaatcg acggccaccg cctgcaccat cctttccggc
    19021 atcgaaatga tcccctcgat gggcaagcga caggcgaggt acgccttcaa tccgaatctg
    19081 tccctggccg agcaattcga aatcctcgcc gcctgattga ccgcatcagg cctctctgcg
    19141 cccctattca gccgttgcaa caaaaccgtt gagcgcaatg cggcgatagg attcattctc
    19201 ggtcgcatgg gtgccgccgg tcgagcagga cggcgacact atgccggcaa tgcaggcgac
    19261 catcgcctgg ccgtcgagca ggtatacgtc gttggcatcg taggctggca tgccatagcc
    19321 cggacttgcc cgttcgatga cgtcaaaacc atcgagcccc cgggcatagc cgagccaacc
    19381 ctggtagagg ccgccgagct tggtcttgcg cgaggaattg tagtgagcgc gatctgcggc
    19441 tcgatgccat ggaaagcagg agcatcgatg ccgatggaac agccaagatt gccgttgccg
    19501 gccgctttcg gcagatccac cttcggagtg ccgatcgcct cgggatcgcc gctgccggtt
    19561 gtcgtggtgg tcgtggccgc ttgctcctca gcggcttgtg gagcggcctc gatatcgctc
    19621 gtctctgccg ccgtacctga tttggctgtc ttggcatcct tgctatcggc tgcgttggca
    19681 tcggcaggtt tggcaccaac cttggccgct gcatcagggc tgccggcggc ggccgttccg
    19741 cccggcgcgg catcttgcgc cacacctgtc gtcggcacca tggtgcccga cgccgatgtg
    19801 cctccgccat ccgccgactg cccgccgcca gtgcggcgcc gccattgccg aatccccccg
    19861 gcgcgctgag ttgagacgaa gtgccctgcg cttcttgcgc aacggcacct atccccgcac
    19921 ttcccctaat atgacaaacg aaagacgttg tgccgtccgg aattatctgt cgttgtccgg
    19981 aattaatccg gacttcggag aggccgggcc catcacgaaa acgatcaatg acctatgtgt
    20041 cgagccgccg ccgcggtggg aatctgcggg cttcagcgtc cgccgagtgc cagcggtagt
    20101 cgttcgttga gggttaccaa acctgtcgca ggtgggttac caatgcgcct aatgaatggc
    20161 cttaggttac caattgaggc cgcaattatc tcaatgaatc agcgccttag cgccagttcg
    20221 aaattaattg tcgttggggc acaatggtaa ccctgttgat cgaagggcat tggtaaccta
    20281 ttcgagcgaa agcagtggga tatgagccat ttagcagtac agctgacgac aaataattct
    20341 ggacgccgac gacagataat tctggacggc acaccagtct gcccttttat gcgactggaa
    20401 acgcacaaaa cgagaacaaa ccaagttatc gatccttagc ttgtccgctt tgagctttga
    20461 gctttagttg agcctccacg cgctctccac tcacaaccgc caatctcacg tttcgccacg
    20521 tcgtttgatg tgcagagaat gccggtctcg ccctcgcgtc actccccctg ccgttgttta
    20581 catgatatgg cacagcctaa gcgatattca gtaatccaca ataattcttt gcatactcga
    20641 gcgggggcca aatcatatgc atcttcactc tttgactttt aggaactttc gtagattgag
    20701 agatacacgc gtcgagtttg caaacgatct gacaatattt gttggagcca acaacagcgg
    20761 caaaacgtct gcaactcatg ctgtggacct atttttgtcc ggttctaagg acaaattcac
    20821 tgtcaatgat ttcagcgcag attgctggcc gggctttgaa aattttccgg cagaagatgc
    20881 ggctgagcaa gccttcgaat ttccagccat aactcttgat gtgtggatca gcgttgatcc
    20941 ggacagtctc taccgggtcg tagatctcct gccccgagcc gcatgggaag gcgcactcgt
    21001 cggcgtccga attgagtttg ccgtgaagaa tgccgcccag acgctggcca gctaccggag
    21061 gatggcgacc gaggccgcga atttcgcgca gaccaaggcc gagcatggcg cggactacaa
    21121 gccctggcct cgccacatgc gagactacct cgcgcgagag ctgaagaatg aatacggctt
    21181 gcgctatttc atcctcgacg aagcgtcact cgaccccgcg aacgctggcg agacttatac
    21241 gccgaaggag attctgggag acaccgagcg cacgggccac tcgatcatca attcgctgat
    21301 caaggtggac ttcctgagcg cgcaacgaca cttgagcgac ggaaacgcac aggctcgaac
    21361 cgaagatctg tctaagcgcc tcagccgttt ctacacgcgc aaccagagca agcgcgaaga
    21421 cgaccacaac gccctgcgcg cgttggcgct atctgaagac caattgacga agcatttttc
    21481 agacgtgttc aaggatacgt tcaaatcgct gcgcaagctc g
//
