LOCUS       NZ_AZUV01000004        14838 bp    DNA     linear   CON 04-JUN-2024
DEFINITION  Mesorhizobium sp. WSM1293 MesloDRAFT_scaffold_2.3_C, whole genome
            shotgun sequence.
ACCESSION   NZ_AZUV01000004
VERSION     NZ_AZUV01000004.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Mesorhizobium sp. WSM1293
  ORGANISM  Mesorhizobium sp. WSM1293
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Phyllobacteriaceae; Mesorhizobium.
REFERENCE   1  (bases 1 to 472966)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            assembly                          :: ALLPATHS v. R37654
            country                           :: Greece
            environment :: Host; Plant root; Root nodule; Soil
            investigation_type                :: bacteria_archaea
            lat_lon                           :: 37.147182 24.514618
            project_name                      :: Mesorhizobium loti WSM1293
            sequencing_meth                   :: WGS
            biotic_relationship               :: Symbiotic
            rel_to_oxygen                     :: Aerobe
            finishing_strategy                :: Level 1: Standard Draft
            GOLD Stamp ID                     :: Gi08882
            Current Finishing Status          :: Level 1: Standard Draft
            Type Strain                       :: No
            Funding Program                   :: DOE-DD 2010
            Isolation Site :: Serifos, towards Hora from beach
            Host Name                         :: Lotus sp.
            Cell Shape                        :: Rod-shaped
            Motility                          :: Motile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28
            pH                                :: 5-8
            Gram Staining                     :: Gram-
            Symbiotic Relationship            :: Mutualistic
            Diseases                          :: None
            Phenotypes                        :: Non-Pathogen
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method                   :: ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: 454-GS-FLX-Titanium; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000513875.1-RS_2024_06_04
            Annotation Date                   :: 06/04/2024 01:41:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,732
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,524
            CDSs (with protein)               :: 6,524
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 76 of 144
            Pseudo Genes (incomplete)         :: 111 of 144
            Pseudo Genes (internal stop)      :: 9 of 144
            Pseudo Genes (multiple problems)  :: 45 of 144
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:13:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14838
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AZUV01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..14838
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     gene            <1..164
                     /locus_tag="M729_RS1000000139835"
                     /pseudo=""
     cand_cluster    1..14838
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14838
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4406:4838](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4407..4838
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     CDS             <5..164
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019862697.1"
                     /locus_tag="M729_RS1000000139835"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="IGRADLPLVTKLPGNVEVKRGSTLRLSANGEDLHIFDADGRSFAL
                     HEVEAKAA"
     gene            complement(244..489)
                     /locus_tag="M729_RS0105450"
     CDS             complement(244..489)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528266.1"
                     /locus_tag="M729_RS0105450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF680 domain-containing protein"
                     /protein_id="WP_027160993.1"
                     /transl_table=11
                     /translation="MNKILIAAAAVLAITGNAFAGSDNFGSNGANQPAATTSVDSTRTS
                     SVRNTGSPVYKLLNSSGDTTQKSAPQGADRNLFGNN"
     gene            complement(559..759)
                     /locus_tag="M729_RS0105455"
     CDS             complement(559..759)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019862695.1"
                     /locus_tag="M729_RS0105455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF680 domain-containing protein"
                     /protein_id="WP_013528267.1"
                     /transl_table=11
                     /translation="MNKILIAAAAVLAITGSAFAGSDNYGSNGPNQPAAAVDQSYTAST
                     KTSEPAAQTPAQGSDRNLFGR"
     gene            complement(839..1036)
                     /locus_tag="M729_RS0105460"
     CDS             complement(839..1036)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019862694.1"
                     /locus_tag="M729_RS0105460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF680 domain-containing protein"
                     /protein_id="WP_013528268.1"
                     /transl_table=11
                     /translation="MKKIILTAAALLAISGSAFAGSDHYGSNAAAATAVDSSYTASTKK
                     SEPAAQAPAQGADRNLFGNN"
     misc_feature    complement(1022..1037)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.37"
                     /tool="antismash"
     misc_feature    1366..1377
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.38"
                     /tool="antismash"
     misc_feature    1544..1560
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.38"
                     /tool="antismash"
     regulatory      1547..1749
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            1864..3111
                     /locus_tag="M729_RS0105465"
     CDS             1864..3111
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019172505.1"
                     /locus_tag="M729_RS0105465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_013528269.1"
                     /transl_table=11
                     /translation="MDIRNDMLRLLKGRRQGFSLEQPFYTDPDYFKLDMELIWYRDWLF
                     IGHDCELPKPGSYITVQVGDYPVVLVRDQHGKINAFHNSCRHRGSRVCNTEKGTAAKLV
                     CPYHQWTYELDGRLLFARQMADGFDKSDFGLKPVACESVGGYIFICLAKEPADFAPMRA
                     MIEPYLLPHRLREAKIAFESTIVEKGNWKLVWENNRECYHCAANHPELCKTFPEAPTVT
                     GVHGADSDPEMVAHWARCEASGLPSKFRIDPAGQYRATRAPLLRDAVSYTMTGKRAVQK
                     NLSDSVSTDRIGSLLLYHYPTTWNHILGDHAVTFRVLPISATETAVTTKWLVHKDAVEG
                     VDYDLAELTHVWTETNDQDRRIVEENAFGILSPAYEPGPYSELHEGGVIQFVEWYASFI
                     GPRLAEGGRPALRSVA"
     gene            3137..4237
                     /locus_tag="M729_RS0105470"
     CDS             3137..4237
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013891625.1"
                     /locus_tag="M729_RS0105470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hybrid-cluster NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_013528270.1"
                     /transl_table=11
                     /translation="MTDLGLYRHLDQMTPWNDRLQVLEVIGVSDEAPDVKTFTFRSDNQ
                     TWFRYKPGQFVTLELPTSDGPLMRTYTLSSSPSRPFSIAVTVKAQAGSTGTRWMFDHLT
                     PGSHVKAYGPTGDFSLHSHPAAKYLFISAGSGVTPMMSMLRWLNDCAPWTDVGFVNCAR
                     RPEEIIFRKELELLGSRMPGLSLGFMIEERSSREGWFGHMGRIDAIRLPLLAPDFRERE
                     IFCCGPDPFMRAVRGMLDAAGFDMAKYHQESFAAPAVEEIPAPFSPPAEDGAAATVEAV
                     TPIRFSHSDVDAECVAGQTVLQTARASGVRIPAACEFGLCGTCKVRKVAGDVEMSHNGG
                     ILDHEIEDGFILACCSKPLSALEIEA"
     misc_feature    complement(3154..3174)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.55"
                     /tool="antismash"
     gene            4407..4838
                     /locus_tag="M729_RS0105475"
     CDS             4407..4838
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013891626.1"
                     /locus_tag="M729_RS0105475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_013528271.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-11,
                     bitscore: 39.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQSGVYAIASKDIVFESFDGEAVVLDLTTGKYFGFSDSGSRLWD
                     ALSSGVPASELVGAATGIGALDAAAIDGFVSQLLEFGLLAAATDGVARPVPSELLAQLA
                     AAGEPLKVDIHDDLADLIVVDPIHEVEEPLGWPAVKQAN"
     aSDomain        4437..4643
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M729_RS0105475_Stand_Alone_Lasso_RRE.
                     1"
                     /evalue="6.80E-13"
                     /identifier="RREFam002.1"
                     /label="M729_RS0105475"
                     /locus_tag="M729_RS0105475"
                     /protein_end="79"
                     /protein_start="10"
                     /score="39.5"
                     /tool="antismash"
                     /translation="SKDIVFESFDGEAVVLDLTTGKYFGFSDSGSRLWDALSSGVPASE
                     LVGAATGIGALDAAAIDGFVSQLL"
     gene            4887..5936
                     /locus_tag="M729_RS0105480"
     CDS             4887..5936
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528272.1"
                     /locus_tag="M729_RS0105480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_027160994.1"
                     /transl_table=11
                     /translation="MPNVTLENLTDYARHVLAQAQSSAAHYPLTCKVGLPHLELTAHVS
                     AGALADAFAHGFVTAPDNRAPADICRIFVAHPGIDGIAAPARWGQGPFTQHGFATRLAE
                     AGLRGNHFHDLDFWQFYDPQRRVGVQLMASADAFPPWEPGAPLRPFLHWEYAARGMRLA
                     HAGTLGTKGRGVLLAGAGGAGKSGTVAAGLLHGLDSVGDDYVLVDLSNGVTARPLFSTL
                     KQDPQGFARLGLKHRLKAHGPLNWQGKHAFHIDDIAPRPVPETLDIVALLVPHIGGGEA
                     SSIVPVSRRDAMIALAPSGIAQMPGERESGFRFFSDLTRLLPCYRLSLGTQRQEIAGTI
                     ADFLVRGAS"
     gene            5933..6685
                     /locus_tag="M729_RS0105485"
     CDS             5933..6685
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006325477.1"
                     /locus_tag="M729_RS0105485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_027160995.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4.1e-25,
                     bitscore: 83.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLSVIMPVYNRERYVVSALRSLVRQRDAADLDIIVIDDGSTDGS
                     AEAVRSMMRENPCIRLFQQSNMGVARARNAGLRQLPPDAEFVSFLDSDDISLAGRFKAD
                     LARFEATSGLELTYSLMTLVDRIDDEKLEPEADCCTMTLRGISLSTALFSRTLVDRIGH
                     FDEDFEQSEDTDYLLRVFETGPRYELPNTVAIYYRRHAGNVTKEHSGRVRNHLRAIHKS
                     MRRRKADPSRREVQGIFELKSPADWRMP"
     gene            6741..7493
                     /locus_tag="M729_RS0105490"
     CDS             6741..7493
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872715.1"
                     /locus_tag="M729_RS0105490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_027160996.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.2e-24,
                     bitscore: 80.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLSVIMPVYNREQFVGLALRSLLRQREDIDLDIIVIDDGSTDGS
                     AAVVRSLIDEAPCIRLFQQINGGVTKARNAGLKQLLPQTRLVSFLDSDDISPIGRFKAD
                     LACFEEDPGLELTYSRMTLVDKINGETLEPAADSHSITVRGIHLSAGIFARDLIERTGG
                     FDEDFKQAEDTDYLLRIFESQAKYVMPDTVALYYRRHPGNMTKEADVPFREFMRAIHKS
                     MKRRKADPSLRRVEGIFDFKDLAQWRFL"
     gene            7493..8170
                     /locus_tag="M729_RS0105495"
     CDS             7493..8170
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006325482.1"
                     /locus_tag="M729_RS0105495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_013528275.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.9e-30,
                     bitscore: 99.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGYGVVIPAFNAAATIGAALNSVLAQTAKAEAIVVVDDGSTDDT
                     AAVIDAMNLPVTVLRQDNTGPGSATTRGIAALSTPLIATLDADDLWLADKIEKQLAYLD
                     RHPGTAGVFTHWRTFRGDSPDLPDAASGAGWSRTTMMIRQEVVQSVGPIIDPPGGRGEM
                     IDWIARVREAGFVLAMLDDVLALRRIRPGSLSYGRDPARDRGYIQVARLAMQRRAQNKA
                     GSS"
     gene            8167..9642
                     /locus_tag="M729_RS0105500"
     CDS             8167..9642
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528276.1"
                     /locus_tag="M729_RS0105500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_027160997.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.3e-20, bitscore:
                     68.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNARPVRRISRRFPDYGWSWPTGQLDLLLKAALLSDEDAAAACAA
                     RWLDENDIDLVSFREHRLLAAISDRFGRKLAGHTAHPRLVGLQKMLWTKSRMAMREAEP
                     ALKAMADGGADIMLIKGASRIALNASAQRGRVAHDIDILVRPRDMAAVFDILRDRDWQI
                     ASGVSAQYLRTRLASLRSMNFFKGRFGDIDLHQLGYDGSQTSAEDDLAIWQRAVPAQFS
                     GVAVFVPSPADRMALAIAHGGLDAHTHSDWLVDCAVAIHAEDVDWGMFLDIVGRRGLAV
                     PAAVALSYLAFEIGIPVPERTMARIFEMADRAGLSRWSSVLQAKPRTDFGGLVWLSRGL
                     AKQLRLKRKKGRLQQEPPAKPWRGRPAAGKPQAASAPLVFSQAIACPQTTGDMMLDITV
                     RIGVPPVRRRIEMEINDGGEHIARLRAVAISRSGRERVLHFRGKVTLDGARVALTLEAR
                     PSRQFREWNDAATVAAYGALPFQLLSAGFLPIG"
     gene            complement(9683..10429)
                     /locus_tag="M729_RS0105505"
     CDS             complement(9683..10429)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006325500.1"
                     /locus_tag="M729_RS0105505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_027160998.1"
                     /transl_table=11
                     /translation="MSDTAAVQSPWQTAGIVRIEKRTPRVTSFFFQPSRPFAYRAGQHV
                     DVRLTAPDGYQARRSYSIASAPETNGAIELAIEKLDDGEVSPFFHEVAAIGDEIELRGP
                     LGGHFVWPKDESGPLVMVGGGSGVVPLMSMIRHRAVRNSAVPVVLVFSVRVWDEVIFRD
                     ELIALDERQDGFELVLTLTREAARRPADYARRVDVAMMAQAMARLPEPPGLAFVCGSNA
                     FVSAAAQALIDAGVAAEIIRTERYGV"
     gene            complement(10426..11037)
                     /locus_tag="M729_RS0105510"
     CDS             complement(10426..11037)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006325501.1"
                     /locus_tag="M729_RS0105510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_027160999.1"
                     /transl_table=11
                     /translation="MVTRGFSSGRRPPTDDDARIPPGQYLEQGFPVLSAGPTPRVRTED
                     WFFTLKHGPRPIKKWNWAEFNALPLTKMTRDIHCVTAWTKFDTPWQGVLVDDILADAGV
                     EPPTGFTLAHAFDGYTTNVPVKDLTAGKAMVALLYEGKPITPDHGGPARLLVPHLYFWK
                     SAKWLNGLQFTTRDEPGFWELRGYHIYGDPWREQRYTDDP"
     gene            complement(11186..12706)
                     /locus_tag="M729_RS0105515"
     CDS             complement(11186..12706)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528279.1"
                     /locus_tag="M729_RS0105515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegQ family serine endoprotease"
                     /protein_id="WP_027161000.1"
                     /transl_table=11
                     /translation="MSDILRRHRVAALLGAALIISPFVMSFAQSAGNTVPTTQTPVAGI
                     TAPNGSFAPIVAADKPAVVTVTTVMKAQPETMSDASPFDGGSPFDDYFRQFFGDQGMPT
                     PKTPPQQQPQRAEALGSGFIVASDGTIVTNNHVIDGASSIKVTLDDGTELPAKLIGRDA
                     KNDLAVLRIKSDKPLPTVKWGDSDKLMPGDQVLAFGNPFGIGTTVTAGIVSARGRDLHS
                     GPFDDFIQIDAPINHGNSGGPLVDVAGNVVGINTAIYSPNGGSVGVGFAIPSDQAQKVV
                     AKLMKGGSIQYGYLGVQIQEVTPDVASAIGLDHPGGALVSEVNDGSPAAKAGIETGDVI
                     TSFAGQEVKDPKDLSRAVADVAPGATETVDVWRKGKPMRISVDVGQNSADAKTASLDDG
                     SDTPSAGRAPAIGLGLMDITPDIRQQMNLAGKQHGAVVASVNPDKAAAASGIQAGDIIV
                     AVNQVPVKNARQVTQAIAQAGKSGRKSVLLLVERGDAQIYIAVPFANG"
     gene            complement(12952..13671)
                     /locus_tag="M729_RS0105520"
     CDS             complement(12952..13671)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013528280.1"
                     /locus_tag="M729_RS0105520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_027161001.1"
                     /transl_table=11
                     /translation="MPSWFSRSVVDGKTTMLTEPFVHAYVRANIWHLRGRDADLLVDTG
                     MGICPLAPQIETPQGKPLLVVATHIHLDHVGSLHEFPLRAGPRMSAARFETMDEAATYA
                     YMFHDLEGAVSKLPAPGWESAHYRIPPAPLTRTLDEGDVVDLGDRQFRVLHLPGHSPDS
                     IALFDEADGLFFSGDAIYDAMLIDDLPDSDRAAYISTMRRLLDLPIRIGHGGHGPSFDG
                     KRMREIATAYLGRTAGG"
ORIGIN
        1 acatcggccg cgccgatctg ccgctggtga ccaagctgcc cggcaatgtc gaggtcaagc
       61 gcggctcgac attgcggctg agcgccaatg gcgaggacct gcatatcttc gacgcggatg
      121 gacgttcttt cgcgttgcat gaagtggaag caaaggcggc ttaaccgcaa ttaccgtgtc
      181 aggcacaaaa aagngcggcg ggccgggccc gccncncttt gacttggaga tcgacttcgg
      241 ttgttagttg ttgccgaaga ggttgcggtc ggcaccttgc ggagcagact tctgggtggt
      301 gtcacccgac gagttcagca gcttgtaaac cggcgaaccg gtgttgcgta ccgaagaggt
      361 gcgcgtgctg tcgaccgaag tcgtggcggc aggctgattg gcaccattgg agccaaagtt
      421 gtcgctgccg gcgaaggcat tgccggtgat ggccagaacg gcggcggcag caataaggat
      481 cttgttcatt ttagtctcct gaattctgga tttcgccagg acggcagaca cagctgccgt
      541 cggttgcgaa attggttgtt agcgaccgaa gaggttacgg tcgctgccct gagcgggcgt
      601 ctgggcagcc ggttccgagg tcttggtgga agccgtgtac gactggtcca cagcggcggc
      661 aggctggttg gggccgttcg aaccgtagtt gtcgctgccc gcgaaagcgc tgccggtgat
      721 ggccagaacg gcggcggcag caatgaggat cttgttcatc ttgaatactc ctgaatgtct
      781 gaatttcgcc acggcggcgg gcaagcccgc cgtcgaccgg gaaactggga atcggctgtt
      841 agttgttgcc gaagaggttg cggtcagcac cctgggcagg cgcctgagca gccggttccg
      901 acttcttggt cgaagcggtg tacgagctgt cgacagcagt ggctgccgcg gcgttggaac
      961 cgtagtggtc gctaccagcg aaggcgctgc cggaaatggc cagaagggct gcggcagtga
     1021 gaatgatctt tttcattttt ggtactccag tatcgtcttt tttccgtccg tctagcggcg
     1081 tgtcttggaa atgaaatcgc gtcgttcgga cagccccgat gtgggagggc aaggtcgtct
     1141 tttccaatca cgaagttgtt ccgtgtggac catgaatcca caccttgaaa ttgtgccaac
     1201 ggaatctagg gatgcatttt tcttcttcat atcagtgtgt taggtgtaga cacttgattg
     1261 atcactgact gtttcagagg cccagcgttc acaccgtcct gcacgcaccg tcaacagaaa
     1321 cgaaccgttc ggttcgattt tagggcaagc taatagtcac ttttcgaaac cgttaacctt
     1381 ttttgacccc cgcgaagggt cggattcggg aagatcgcag ccggcaaatg gccgcccggg
     1441 aggtgggatc tcggcccgcg acgagctgca gtagcgtttc gcatgccgtg tcgcgccgca
     1501 tggatacgat gtcgttttca tgccgacggc gcgcccgcga tcgtggttag atcataccat
     1561 ctcaggtgcc gcttcgtgac gacgaggcgg agaattggga agccggtcag aatccggcgc
     1621 tgcccccgca acggtggtgg agttcaagtc gcaacgggag accactgggc aaccgcctgg
     1681 gaaggtgtcg cgatggtccg caaggacaac tccagagccc ggaaaccagc ccgagatttt
     1741 tagactcgac tgatcgcggt gggcggtcaa gaggtggata gcgcatgtcc ggcacacagc
     1801 cggcctgtgt ttcaatcctt cctccatcac caccagttca gtccttagaa acgaggacag
     1861 gacatggata tccgcaacga catgctgagg ctcctgaagg ggcgccggca aggcttttcg
     1921 ctggagcagc ccttctacac cgatccagac tacttcaagc tcgacatgga gctgatctgg
     1981 tatcgcgact ggctgttcat cggccatgat tgcgaactgc ctaagccggg cagctacatc
     2041 accgtgcagg tcggcgacta tccggtcgtc cttgtccgcg accagcacgg caagatcaac
     2101 gccttccaca attcctgccg ccatcgcggc agccgcgtgt gcaacacgga gaagggtacc
     2161 gcggcaaagc tcgtctgccc gtatcatcag tggacctacg agctggacgg ccgcctgctg
     2221 tttgcccgcc agatggccga cggtttcgac aagagtgatt tcggcctgaa gccggtcgcc
     2281 tgcgagagcg tcggcggcta catcttcatc tgcctggcca aggaaccggc agatttcgcg
     2341 ccgatgcggg cgatgatcga accctatctt ttgccgcacc ggctgcgtga agcaaagatc
     2401 gccttcgaga gcacgatcgt cgagaagggc aactggaagc tggtctggga aaacaaccgc
     2461 gagtgctacc actgcgccgc caatcatccc gagttgtgca agaccttccc cgaggctcca
     2521 accgtaaccg gcgtccatgg cgccgacagc gaccctgaaa tggtcgcaca ctgggccaga
     2581 tgcgaggcat caggcttgcc gagcaaattc cgcatcgatc cggcagggca gtaccgcgcc
     2641 acccgcgcgc cgctgctgcg cgatgccgtc agctacacca tgacgggaaa acgggcggtc
     2701 cagaagaacc tgtccgacag cgtttcaacc gaccgcatcg gctccttgct gctctatcac
     2761 tatccgacga cctggaacca tatcctcggc gaccacgccg ttaccttccg cgtgctgccg
     2821 atcagtgcca cggaaaccgc ggtgaccacg aaatggctcg tccacaagga tgcggtcgaa
     2881 ggcgtcgact acgacctcgc tgagctcacc catgtctgga ccgagaccaa cgaccaggac
     2941 cgccgcatcg tcgaggaaaa cgccttcggc atcctgtcgc cggcctatga accaggcccc
     3001 tattcggagc tgcatgaggg cggcgtgatc cagttcgtcg agtggtacgc gtcgttcatc
     3061 gggccgcgcc ttgccgaagg cggccggccg gccctgcgca gcgtcgccta gcccagggga
     3121 caagaggatg aatgcgatga cggaccttgg cctctatcgc catctcgacc agatgacgcc
     3181 ctggaacgac aggctgcagg tgctggaagt gatcggcgtc agcgacgaag cgcctgacgt
     3241 gaagaccttc accttccgct ccgacaacca gacctggttc cgctacaaac cggggcagtt
     3301 cgtgactctg gaactgccga catcggacgg gccgctgatg cgcacctaca cgctgtcgtc
     3361 ctcgccgtcg cggccgttct cgatcgcggt gacggtcaag gcgcaggcgg gcagcaccgg
     3421 tacgcgctgg atgttcgacc atctgacgcc cggttcgcac gtcaaggcct atgggccgac
     3481 cggcgacttc tcgctgcaca gccacccggc cgccaaatac ctgttcattt cggccggttc
     3541 cggcgtgacg ccgatgatgt cgatgctgcg ctggctgaac gactgcgcgc catggaccga
     3601 tgtcggcttc gtcaactgcg cgcgccgccc ggaagagatc attttccgca aggagctcga
     3661 actgctcggc agccgcatgc ctgggctgtc gctcggcttc atgatcgagg agcggtcgag
     3721 ccgcgagggc tggttcggcc atatgggccg catcgacgcg atccggctgc cattgctggc
     3781 gcccgatttc cgtgagcgcg agattttctg ctgcggcccc gatcctttca tgcgcgccgt
     3841 gcgcggcatg ctggacgccg ccggcttcga catggcgaaa taccatcagg aaagctttgc
     3901 cgcgcctgcc gtggaggaga tcccggcgcc gttctcgccg ccggcggaag acggcgccgc
     3961 tgccaccgtg gaggccgtga caccgatccg gttctcgcat tccgatgtcg atgccgaatg
     4021 cgtcgccggc cagaccgtgc tgcagacggc acgcgcctcg ggggtgcgga ttcccgccgc
     4081 ctgcgagttc ggcctgtgcg gcacctgcaa ggtgaggaag gtcgcgggcg acgtggagat
     4141 gagccacaat ggcggcatcc tcgatcacga aatcgaggac ggctttatcc tcgcctgttg
     4201 ctcgaagccg ctttcggcgc ttgaaatcga ggcgtgaccg gcaggcacgg tcagagactg
     4261 tccatgcccg cgcggcctgc agctgcgctc gcccgggcct acgccatctt gccaaaaacc
     4321 ctgcaaatgg ttagacgcct gcaacggtgg ggttgaccgt agggcccgaa gatcatctcc
     4381 gcggcctgct tcggcgggga gcaaacatgc gacaatccgg cgtatatgcc attgccagca
     4441 aggatatcgt ctttgaatcc ttcgatggcg aagccgtcgt tctcgacctg accaccggta
     4501 aatatttcgg cttctctgat tcaggcagca ggctttggga tgcactgtcg tccggcgtgc
     4561 ctgcctccga actggtcggc gccgcgaccg gaattggcgc cctcgatgcc gccgcgattg
     4621 acggctttgt ttcacaattg ctcgaattcg gtttgctggc ggccgcaacc gatggcgtgg
     4681 caagaccggt tcccagcgaa ttgctggctc agctcgccgc tgccggcgag cccctcaagg
     4741 tcgacatcca tgacgacctt gccgacctca ttgtcgtcga tcccatccac gaggtcgagg
     4801 agcccctcgg ctggcccgca gtgaagcagg ccaactgagg cgcccgccag gctctcgttg
     4861 ccggacagct ccggaacagg cagaccatgc cgaacgtcac tctcgaaaac ctgactgact
     4921 acgcacgtca tgttctggcg caagcgcaga gcagcgccgc gcattatcca ctgacctgca
     4981 aggtgggctt gccgcatctg gagttgaccg ctcatgtgag tgccggcgcg ttggcggatg
     5041 ccttcgctca tggctttgtc acggctccgg acaaccgagc gcctgccgac atctgccgca
     5101 tcttcgtcgc acatcccggc attgacggca tcgcggcacc ggccagatgg ggccaaggac
     5161 ccttcacgca gcatggcttc gccaccaggc tggcggaagc cggattgcgc ggcaaccatt
     5221 tccatgacct ggatttctgg cagttctatg atccgcaacg tcgcgttggc gtgcaattga
     5281 tggcctcggc cgatgccttt ccaccgtggg agccgggagc gccgctgcgc cccttcctcc
     5341 attgggaata tgcggcacgt ggcatgcggc tggcccatgc ggggacgctc ggcaccaaag
     5401 gcaggggcgt actgctggcc ggcgcgggcg gcgccgggaa atccgggacc gtcgccgccg
     5461 gcctcctcca cgggctggac agcgtcggcg acgattatgt gctggtcgac ctctccaacg
     5521 gcgtgactgc ccgcccgttg ttttcaacac tcaagcagga tccccaggga ttcgcgcgac
     5581 ttgggctgaa gcaccggctg aaggcgcacg gtccgctcaa ctggcaaggc aagcatgctt
     5641 ttcacattga cgacattgcg ccacggccgg tgcccgaaac tctggacatc gttgcgctgc
     5701 tggtgccaca tatcggcgga ggcgaggcaa gttcgatcgt gccggtgtcg cgcagggatg
     5761 ccatgattgc cttggcgccg tccggcatag cgcagatgcc gggcgagcgg gagagcggct
     5821 ttcgcttctt cagcgacctg acccgcctgc tgccgtgcta tcgtctgtcg ctggggacgc
     5881 agcgacagga gatagccggc acgattgcgg actttcttgt gcggggcgct tcgtgaaact
     5941 gagcgtgata atgcccgtct acaaccgtga gcgctatgtc gtttcggcat tgcgctcgct
     6001 ggtgcggcag cgggacgccg ccgatctcga catcatcgtc atcgacgacg gttcgaccga
     6061 cggctctgct gaggccgtac gctcgatgat gcgcgaaaac ccctgcatcc gactcttcca
     6121 gcaatcgaac atgggcgtgg ccagggcgcg caacgccggg ctgcggcaac tgccgccgga
     6181 tgcggagttc gtgtcattcc tggattctga cgacatctcg ctggccggac ggttcaaggc
     6241 cgatctcgcc cgcttcgagg ctacctccgg gcttgagcta acctattcgc tgatgacgct
     6301 ggtcgaccgg atcgacgacg agaagctcga gccggaggcg gactgctgta ccatgacgct
     6361 tcgcggaatt tcgctgagca ccgctctctt cagtcgaacg cttgtcgatc gcatcggcca
     6421 tttcgacgag gactttgagc agtccgagga cacggattat ctgttgcgag tcttcgaaac
     6481 cggtccgcgc tacgaattgc cgaacaccgt cgcgatctac taccgacgcc acgccggaaa
     6541 tgtcaccaag gaacatagcg gcagggtccg caaccacttg cgtgcaatcc acaagtctat
     6601 gcggcggcgc aaggccgatc cgtcacggcg agaggtccag ggcatcttcg aattgaagag
     6661 tcccgccgat tggcggatgc catgatgctc gagacaatcg gctcggatca gccaagcccg
     6721 caacgctgct ggagacgccg atgaggctga gcgtcatcat gccggtctac aatcgcgaac
     6781 aattcgttgg cctggcgctg cgctcgttgc tcaggcagcg cgaagacatc gatctcgaca
     6841 tcatcgtcat cgacgacggg tcgaccgatg gctcggcagc cgtcgtacgg tcgttgatcg
     6901 acgaggcccc atgcattcgt cttttccagc agatcaatgg cggggtcacc aaggcgcgca
     6961 atgccgggct gaagcagttg ctgccgcaga cgcgtctggt gtcgtttctc gattcggacg
     7021 acatctcccc gataggccgc ttcaaggcgg atctcgcctg cttcgaagag gatcctggcc
     7081 tcgagctgac ctattcgcgc atgacgctgg tcgacaagat aaatggcgag acactggaac
     7141 cggccgccga cagccactcc atcaccgtgc gggggatcca cctgtccgcc gggatcttcg
     7201 cgcgagacct catcgagcgc accggtggtt tcgacgagga tttcaaacag gccgaggaca
     7261 ccgactatct gttgcgtatc tttgagagcc aggcaaaata cgttatgccc gatacggtgg
     7321 ctctctatta caggcgtcat cccggcaaca tgaccaagga agccgatgtg ccctttcgcg
     7381 agttcatgcg cgccattcac aagtcgatga agcgtcgcaa ggccgatccc agcttgcgcc
     7441 gggtggaggg gatcttcgac ttcaaggatc tcgcgcagtg gcggttcctt tgatggcagg
     7501 ctatggcgtc gtcattccgg ctttcaacgc ggccgccacc ataggcgcgg ccctgaactc
     7561 cgttctggcc cagacggcaa aggcggaggc catcgttgtg gtcgacgacg gttcgaccga
     7621 tgatacggcc gcggtgatcg atgcgatgaa cttgccggtg acggtgctgc gacaggacaa
     7681 taccggaccc ggcagcgcaa cgacccgtgg cattgcggca ctctcgacgc cgctcatcgc
     7741 gacgctcgat gccgacgatt tgtggttggc ggacaagatc gaaaagcagc tggcctatct
     7801 cgaccgtcat cccgggacag cgggcgtctt tacgcattgg cggacgtttc gcggcgacag
     7861 ccccgatttg cccgatgcgg ccagtggagc gggctggtcg cgcacgacga tgatgatccg
     7921 ccaggaggtg gtgcagagcg tcggtcccat catcgaccca ccaggcggtc gcggcgagat
     7981 gatcgactgg atcgcccggg ttcgtgaggc aggctttgta cttgccatgc tcgacgacgt
     8041 gcttgcattg cgccgcatcc gtccgggcag cctttcctac ggccgcgatc cggcacgcga
     8101 ccggggctat atccaggtcg caaggctcgc catgcagcgg cgggcccaga acaaggcggg
     8161 ctccagttga acgccaggcc tgttcgccgc atcagccgcc gcttcccgga ctatggctgg
     8221 tcgtggccca ccggccagtt ggacctgttg ctgaaggcgg cgctgctctc cgatgaggac
     8281 gcagccgctg cctgcgccgc gcgctggctc gacgagaacg acatcgacct cgtctcgttt
     8341 cgagaacatc gtctgctcgc cgccatctcc gacaggttcg gcagaaaact ggccgggcat
     8401 accgcgcacc cgcgcctcgt cggcctgcag aagatgctgt ggacgaagtc gcgtatggcg
     8461 atgcgcgagg ccgagccggc gctgaaggcg atggccgacg gcggcgccga catcatgctg
     8521 atcaagggcg ccagccgcat tgccttgaac gcgtcggcgc agcgtggtcg ggtggcgcat
     8581 gacatcgaca tactggtgcg cccgcgcgac atggctgccg tcttcgacat cttgcgcgac
     8641 cgcgactggc agatcgcctc gggcgtcagc gcgcaatatc tgcgaacccg gttggcgtcg
     8701 ctgcggtcga tgaacttctt caagggccgt ttcggcgaca tcgacctgca ccagctcggc
     8761 tatgatgggt cgcagacgag cgcggaagac gacctggcga tctggcaacg ggcggtcccg
     8821 gcacaattca gcggcgtcgc ggtcttcgtg ccatcgccgg ccgatcgcat ggcactggcc
     8881 atcgcccatg gcggcctcga cgcccacacc cacagcgact ggcttgtcga ctgcgcggtc
     8941 gccatccatg ccgaagacgt cgattggggg atgttcctcg acatcgtcgg aagacgcggc
     9001 ctggcggttc cagcggcggt ggcgttatcc tatctggcgt tcgagatcgg cattccggtg
     9061 ccggaacgga caatggccag aatcttcgag atggccgacc gggctggcct gtcgcgttgg
     9121 tcgtcggttc tgcaagccaa gccgcgcacg gatttcggcg gcctggtctg gctgtcgcgc
     9181 ggccttgcca agcagttgcg cctgaagcgg aagaagggcc ggttgcagca ggagccgccc
     9241 gccaaaccct ggcgcgggag accggccgcg ggcaagccgc aagccgcatc ggcgcctctg
     9301 gtgttttcgc aggccatcgc ctgtccgcaa acgaccggcg acatgatgct cgacatcacc
     9361 gtcaggatcg gcgttccgcc ggtccggcgc cgcatcgaaa tggagatcaa tgacggtggc
     9421 gagcatatcg ctcgcctgcg tgccgtggct atcagccgat ccggcaggga acgcgtgctg
     9481 cattttcgcg gcaaggtgac gctcgacggc gcgcgagttg ccttgacgct cgaggcgcga
     9541 ccatcgcgac agtttcgcga gtggaacgac gcggccacgg tggccgccta tggcgccttg
     9601 cctttccagt tgctgtcggc gggtttcttg ccgatcggct gaaggcgaat ccgacgaacc
     9661 tttctcgcaa ggcggcgtcc gctcaaactc cgtagcgttc ggtgcggata atttcggctg
     9721 caacgccggc atcgatcagc gcctgggctg ccgcggaaac gaaggcattg gagccgcaga
     9781 cgaaggcgag accgggcggc tcgggcagcc gcgccatggc ttgcgccatc atcgcgacgt
     9841 ccacccgccg cgcatagtcg gccgggcggc gtgcggcttc gcgggtcagt gtcagcacca
     9901 gctcgaagcc gtcctgacgc tcgtcgaggg cgatcagctc gtcacgaaag atcacttcgt
     9961 cccagacccg gaccgaaaag accaggacga cgggcaccgc tgaattccgt acggcgcggt
    10021 ggcggatcat cgacatcaag ggcacgacgc ccgaaccgcc gccgaccatc acaagcggcc
    10081 cactctcatc cttcggccag acgaaatgcc cgccaagcgg cccgcgcagt tcgatttcgt
    10141 cgccaattgc cgcgacttcg tggaagaagg gcgaaacctc gccatcgtcg agtttttcga
    10201 tcgccagttc gattgcgcca ttcgtttcgg gcgcggaggc gatggaatag gagcggcgcg
    10261 cctgatagcc atccggcgcc gtaagcctga cgtcgacatg ctgcccggcg cgataggcga
    10321 agggccgaga cggctgaaaa aagaagctgg tgacacgcgg cgtgcgcttt tctatgcgga
    10381 cgatgccggc tgtttgccag ggcgactgca ctgccgccgt atcgctcatg gatcgtccgt
    10441 gtagcgttgc tcgcgccatg ggtcgccata gatatggtag ccgcgcaatt cccagaaacc
    10501 gggctcgtcg cgcgtggtga attgcaggcc gttcagccat ttggccgact tccagaaata
    10561 gagatgcggc accagcagcc ttgccgggcc gccatgatcc ggcgtgatcg gcttgccttc
    10621 gtagagcagc gcgaccatgg ccttgccggc ggtgagatcc ttgaccggca cattggtggt
    10681 gtaaccgtcg aacgcgtgcg ccagcgtgaa gccggtcggc ggctccacac ccgcgtcggc
    10741 aaggatatcg tcgaccagca cgccctgcca cggcgtgtcg aacttggtcc atgcggtcac
    10801 gcaatggata tcgcgcgtca tcttggtcaa cggcagcgcg ttgaactcgg cccagttcca
    10861 tttcttgatc ggccgtggcc catgtttcag cgtgaaaaac caatcctcgg tgcgcacgcg
    10921 cggcgtcgga ccggccgaca gcaccggaaa accctgttcc agatattggc cgggcgggat
    10981 gcgggcatcg tcatcggttg gcgggcgccg tcctgaagag aaacctcggg tgaccatcgc
    11041 ggcaatctcc tgcatcgggc cgacatcagc ctgatgcaat gttctcgaag atgtcgtggc
    11101 gggcaaccaa aatcttgacg ggcggaggcc ggaggggatc gtcgccgacg aaccctgccg
    11161 gtcccgttca cgtcaaggcc attactcagc cattggcaaa aggcaccgcg atgtagatct
    11221 gagcgtcgcc acgctcgacc agcaacagca ccgacttgcg gccagacttg ccggcttgcg
    11281 cgattgcctg ggttacctgc ctggcgttct taaccggcac ctgattgacg gcaacgatga
    11341 tgtcgccggc ctgtattccg gaagcggcgg cggctttgtc gggattgacg ctggcaacca
    11401 ccgcgccgtg ctgcttgccg gctaggttca tctgctggcg aatgtcgggc gttatatcca
    11461 tcaagccgag ccctatcgcc ggagcgcgcc cggcactggg cgtgtcggac ccgtcatcca
    11521 gcgacgcggt cttcgcatcg gcgctgttct ggccgacatc gacggaaatc cgcatcggct
    11581 tgcctttgcg ccagacatcg accgtttccg tggcgcccgg cgcgacatcg gcgaccgccc
    11641 gcgacaggtc cttggggtcc tttacctcct gcccggcaaa gctggtgatg acgtcacccg
    11701 tctcgatgcc ggccttggcc gccggcgagc cgtcattgac ctctgaaacc agcgcgccgc
    11761 cgggatggtc gagcccgatg gcgctcgcga catccggtgt cacctcctgg atctgaacgc
    11821 cgagatagcc gtactggatg gagccgccct tcatcagctt ggccaccacc ttctgggcct
    11881 ggtccgacgg aatggcaaag ccgacgccga cgctgccgcc attgggcgaa tagatcgccg
    11941 tgttgatgcc gacgacattg cccgcgacat ccaccagcgg gccgccggaa ttgccgtggt
    12001 tgatcggcgc gtcgatctgg atgaaatcgt cgaacggccc gctatgcagg tcacggccgc
    12061 gcgccgagac gatacctgcc gtgacggtgg tgccgatgcc gaacgggttg ccgaaggcca
    12121 gcacctggtc gcctggcata agcttgtcgg aatcgcccca tttgacggtc ggcaggggtt
    12181 tgtccgactt gatcctcagc acggcgagat cgttcttggc atcgcggccg atgagcttgg
    12241 ccggaagttc ggtgccgtcg tcgagcgtca ccttgatcga agaggcccca tcgatgacgt
    12301 gattgttggt gacgatggtg ccgtcggagg cgacgatgaa gccggaaccc agcgcctcgg
    12361 cgcgctgcgg ttgctgttgc ggcggcgtct tgggcgtcgg catgccctgg tcaccgaaga
    12421 actggcggaa atagtcgtcg aaaggcgagc cgccgtcgaa aggagaggca tcgctcatcg
    12481 tttcaggctg tgccttcatg acggtggtga ccgtcaccac cgccggcttg tcggcggcca
    12541 cgatgggtgc gaacgagcca ttgggcgctg tgatgccggc gacaggtgtc tgggtcgtcg
    12601 gaacggtgtt gcccgcgctt tgggcgaaag acatgacgaa gggggatatg atcagcgcag
    12661 cgcccagcaa ggccgcgacg cgatgcctac gaaggatatc tgacatggtc gtttgtccgg
    12721 gcgagagttg atccagcgcc gtggcctccc atgcgggaaa tcggtcatcg gcgtgtcgag
    12781 gttgcaattg cccgtctcgc ctacatggca gccaaccgga tcgacggcct tgcatctagg
    12841 gcgcggattg gcccgattta gggttttcgg gcgaccttac gaagatttaa tatccgcacg
    12901 gcggcagggt cacaaagtcg tcgggtcacg ccttgctgcc tcgctggagc ctcagccacc
    12961 ggcggttcgt ccgagatagg ccgtagcaat ctcgcgcatg cgcttgccgt cgaagctcgg
    13021 tccgtgtcct ccatgaccga tacggatcgg caggtcgagc aggcgccgca tcgtactgat
    13081 ataggcggcc cggtcggaat ccggcaggtc gtctatcagc atggcgtcgt agatggcatc
    13141 gccgctgaag aacagtccgt cggcctcgtc gaacagcgcg atcgaatccg gtgaatggcc
    13201 cggcaaatgc agcacgcgaa attgccggtc gccaagatcg acgacatcgc cctcgtccag
    13261 ggttcgcgtc aacggcgcgg gcgggatcct gtagtgggcc gactcccatc cgggcgccgg
    13321 cagtttcgag acggcaccct cgaggtcgtg gaacatgtag gcgtaagtcg cggcctcatc
    13381 catggtctcg aaccgagccg cgctcattct tggcccggcc cgcaacggga attcatgcag
    13441 cgagccgacg tggtcgagat ggatgtgggt ggcaacgacc agcaacggct tgccctgcgg
    13501 cgtctcgatc tgcggcgcca gcggacagat gcccataccg gtgtcgacga gcaggtcggc
    13561 atcgcgaccg cgcagatgcc agatattggc ccgaacatag gcatgcacga agggctcggt
    13621 cagcatcgtc gtcttgccgt cgaccacgct cctgctgaac cagctcggca tcaagtgtga
    13681 gtccggcata cgaagtgagc cgggcatcag gtgtgagccc ggcatcagac gaagggcttc
    13741 ccgaccttgt acttttccgg caccagccgc ttgagatagg ccatgccggc atccgacagc
    13801 tgattgacgt cgggcttcat gaaatggtca ggcatgtggc gggtcttgcc ggcgacgttc
    13861 ttgagcggca ctttcttcag caccgttctg gtgccgtcat attgcagcgc caccgagccg
    13921 ccgccctgtt cggcgacggt gacggcgaaa gcgccagcat cgaaagcctc ctgcgcgtcg
    13981 accgcgctga tggcgccgat atagccgcgc ggcatgtagc cgagcgcgtc gacgcgggca
    14041 cgcttgccgg gcaggccttc cgccaacgcg cgctcgagtg cggccggcag atcgctgccc
    14101 gacagcttga cgttgccatg cgcgtcgcgc tcaagcttgt ccggcggcac caggctttcg
    14161 accaatgcct tgccgtcggc ggtgctgacg ccttccgaaa cggcgacgat gcagcgcttg
    14221 tggcgatcga gcgtggcacg cacgtcgtcg atgaagccag cggccgagaa cggccgctcg
    14281 ggcacgtaga cgagatgagg gccgctgtcg gggtcgagct gccaggcagc ggcagccgcg
    14341 gtcaggaagc ccgcatgccg gcccatgacg atgccgacat agatgccggg cagcgcgcga
    14401 aaatcgagat cgacggacag gaaggcgccg gcgacgaact cggccgccga aatgaagccc
    14461 ggcgtgtggt cgttttcctc gagatcattg tcgatggttt ttggcgcatg aacaaaggca
    14521 attgagccgc cggcggcgtc ggtcaggatc tgctgggtac ccgacgtgtc gttgccgccg
    14581 atatagatga aggcgtcggc gccggccttc ttcaggccgt tgaggatgac atcgcaatag
    14641 gtggcgtcgg gcttgtcgcg cgtcgagccg agggcggcgc tcggcgtgcc ggcaatcagc
    14701 cgcaggcggt cttccggaat ggcggaaagg tcgacataat tgccgtcacg gatgccgcgc
    14761 acgccatgga tcgagcccag caccttggca ccgggatgcc gcttgcggat ctccagcgtc
    14821 gccccgacaa ccgtctgg
//
