LOCUS       NC_022873              23507 bp    DNA     circular CON 15-AUG-2024
DEFINITION  Bacillus thuringiensis YBT-1518, complete sequence.
ACCESSION   NC_022873
VERSION     NC_022873.1
KEYWORDS    RefSeq.
SOURCE      Bacillus thuringiensis YBT-1518
  ORGANISM  Bacillus thuringiensis YBT-1518
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 6002284)
  AUTHORS   Wang,P., Zhang,C., Guo,M., Guo,S., Zhu,Y., Zheng,J., Zhu,L.,
            Ruan,L., Peng,D. and Sun,M.
  TITLE     Complete genome sequence of Bacillus thuringiensis YBT-1518, a
            typical strain with high toxicity to nematode
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6002284)
  AUTHORS   Wang,P., Zhang,C., Guo,M., Guo,S., Zhu,Y., Zheng,J., Zhu,L.,
            Ruan,L., Peng,D. and Sun,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2013) State Key Laboratory of Agricultural
            Microbiology, College of Life Science and Technology, Huazhong
            Agricultural University, 1 Shizishan Road, Wuhan, Hubei 430070, P.
            R. China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 1.04
            Reference-guided Assembly         :: NC_005957.1
            Genome Coverage                   :: 190X
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497525.1-RS_2024_08_15
            Annotation Date                   :: 08/15/2024 02:37:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,968
            CDSs (total)                      :: 6,823
            Genes (coding)                    :: 6,362
            CDSs (with protein)               :: 6,362
            Genes (RNA)                       :: 145
            rRNAs                             :: 15, 15, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 15, 15, 15 (5S, 16S, 23S)
            tRNAs                             :: 95
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 461
            CDSs (without protein)            :: 461
            Pseudo Genes (ambiguous residues) :: 0 of 461
            Pseudo Genes (frameshifted)       :: 191 of 461
            Pseudo Genes (incomplete)         :: 266 of 461
            Pseudo Genes (internal stop)      :: 128 of 461
            Pseudo Genes (multiple problems)  :: 100 of 461
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:11:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1478480
            Orig. end                         :: 1501987
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP005935.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23507
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="3"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23507
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13507](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13507)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(107..125)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.43"
                     /tool="antismash"
     gene            155..514
                     /locus_tag="YBT1518_RS07530"
                     /old_locus_tag="YBT1518_07260"
     CDS             155..514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016082428.1"
                     /locus_tag="YBT1518_RS07530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07260"
                     /product="DUF4029 domain-containing protein"
                     /protein_id="WP_000946150.1"
                     /transl_table=11
                     /translation="MLRRKLLYLLLTVPLYAWLISMTKIELMALFLGYVFIFSNLNRIQ
                     EQSILEICLFSISIELFSIVSIVLLNELFLRIHSFTLMKFWNIALQAICTYIVFVVLKK
                     IIGQQTVFQDNRKWE"
     misc_feature    complement(522..536)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    523..537
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            629..2128
                     /locus_tag="YBT1518_RS07535"
                     /old_locus_tag="YBT1518_07265"
     CDS             629..2128
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126004.1"
                     /locus_tag="YBT1518_RS07535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07265"
                     /product="L-lactate permease"
                     /protein_id="WP_023521440.1"
                     /transl_table=11
                     /translation="MAILLALIPIMMIFICLFLFKQTSLRSALISYAVCVGIVLLSPTF
                     QLGISETLHATIKGWLICFIVGYVLFFGIFLFHLMNKMGYIDQVARFLEEVTHDRLLQM
                     LLMCFGICPLIESVSGFGIGFMVAAPIFLSLGYKPFQAVLLSFIGLLASSWGAMATGTI
                     IGSQLINMPLTTLGTNTALLSIPMFAYFVILSLYVVGGWQAVIEKWKEGVGFFLLFSLG
                     IYLSNAYVSVELAGILSSIVTITFGFLIIKLKGKSEQNLITEHAAATEREVSIIKIISP
                     YIFLTVCILLSRLVPALHDLFRSYAVLDLKSYSYKLELLYSPGFWLGMTCLFTIIFFRI
                     PSNIIKQSLSQTIKQWIPFAITTTMFIAISELMGASGMHLLLAKIAGETFGTFFVFFAP
                     FIGAIGGFLTGSNAGSNAMFIKLQMQTAQNVALPWQYVTTLQNTASSVATIACPSRITL
                     GAYLCNIPYRENELLKKTTLMIFGAVLLVMVEVIVWYMLRN"
     misc_feature    complement(658..673)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            2219..2902
                     /locus_tag="YBT1518_RS07540"
                     /old_locus_tag="YBT1518_07270"
     CDS             2219..2902
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128612.1"
                     /locus_tag="YBT1518_RS07540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07270"
                     /product="DUF2278 family protein"
                     /protein_id="WP_001128611.1"
                     /transl_table=11
                     /translation="MPLKNYGVLKGTVIQSKIGKGKTPHYQVHLQGETGVDYRIAINVK
                     SQSYPSEVLYFASNNIRSEAIHILPTLPFGFTEVKNNEPKVALDYVRGNLFDSKQMIPL
                     PPEKAGADNDLNEKIERYIKRAMEEKAIIYAFGERWGPEENTPDSYFHFKPGNGIHDIH
                     MNQGNVEKWQGDDGIWQDGGILIHFEKEEEWIGIFLAFQSQSWCTDEEGHARVPVEHCD
                     YKGNN"
     gene            complement(2917..3750)
                     /locus_tag="YBT1518_RS07545"
                     /old_locus_tag="YBT1518_07275"
     CDS             complement(2917..3750)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017762920.1"
                     /locus_tag="YBT1518_RS07545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07275"
                     /product="hypothetical protein"
                     /protein_id="WP_023521441.1"
                     /transl_table=11
                     /translation="MALVNSIFQILLTSVIQLLSLIGVIIVIGFLLGYLESLTRMYWSR
                     AFGRKGFLLTAWIGVPIHELGHAIMCVLFRHKIVATQFFPTDTSQGALGYIQHQYNQKS
                     VYQRIGNFFIGIGPIISGITALILLMRYFVPESYFLFNTTLEKTIASTSINVEMIQNML
                     LSTFVLLKSLFTIGNLLNPSFWLFLFIAICISAHIALSKPDIKESIDGVVVMFIVLFLF
                     NIIAGLFQYDSNQLIGQVMKYNMYLIAFSSVALLFSCLSTLVSFSFYKIRRGRSF"
     gene            3947..4732
                     /locus_tag="YBT1518_RS07550"
                     /old_locus_tag="YBT1518_07280"
     CDS             3947..4732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650096.1"
                     /locus_tag="YBT1518_RS07550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07280"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_023521442.1"
                     /transl_table=11
                     /translation="MKCPSCHTKNAVEAKFCGNCGHSLTEEVVVSSGQEEGPEQARAAQ
                     AKEARPNETVEQAKRFASGYFQFFKHALQAPTAIMKSGAIEVRNGIISLVLICFLGACI
                     FYRMMSAASAVTRTFAPDISTPTFFGESITVFFFLLILTLFVGFIIFVSGKMMKSSFSF
                     LEVFGIWGTIATPAIVILVLSFLFSFLLIFFLPILLSVVATYIGISITVAVLKLDNGGL
                     DLVYTLIIANVLIGIATFIVLWSYISTIIQALTQGITGF"
     gene            4752..5987
                     /locus_tag="YBT1518_RS07555"
                     /old_locus_tag="YBT1518_07285"
     CDS             4752..5987
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017672808.1"
                     /locus_tag="YBT1518_RS07555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07285"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_001099935.1"
                     /transl_table=11
                     /translation="MNVCTKCGVQFEDGVQFCQNCGMKRGSPVVKKNMSSGTKVGITLL
                     ALFVIAIIGLYLYGSSYYTQVAQVDRMITILQERDGEKLAEIVTADDPSVMITRENLTP
                     LFSYIKENPAYVNELKEYLRQGEKQRDGIERADFSLTKDGKYFFIFDRYKLKAKTYYTT
                     LLTNEKGVALKMNGKEIDKTDDKKFEKQYGPFLPGNQVFQSEYKNDYVKLSREEKVVLM
                     KQSQNNVTIDLTLQGQYITVQTNAPGATLYVNQKPVTALAGEAITWGPVATDGSAKIYL
                     ERNGENGRETTKLETVTALSSYNLPFQTKSAEKTVVYNVTPTPATGYVYNGFIFPDSDI
                     RKLTSTDLTYLSKEQLKIARNEIYARHGHIFQTKDMQAYFAKQSWYRENPYFTGTLTDI
                     ETYNIELIKSRE"
     gene            complement(6027..6458)
                     /locus_tag="YBT1518_RS07560"
     CDS             complement(6027..6458)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332399.1"
                     /locus_tag="YBT1518_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000332399.1"
                     /transl_table=11
                     /translation="MCAGLLAQFPEEPKEPKPALSLDQEFSINATIYSARAWLSNDETF
                     PQTIWKGSRFASASHAGKSILPIGTVKILNLSDDTITVTASSESDDTLKIVVPPHSEGV
                     LTSNALSDVQASTSGGASKVTFLFHIFFSRDPGSDKKKP"
     gene            6659..7993
                     /locus_tag="YBT1518_RS07565"
                     /old_locus_tag="YBT1518_07290"
     CDS             6659..7993
                     /EC_number="1.8.1.14"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="YBT1518_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07290"
                     /product="CoA-disulfide reductase"
                     /protein_id="WP_023521443.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-65, bitscore:
                     219.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDESANVVTLEKGEIYSYAQCGLP
                     YVISGAIASTEKLIARNVKTFREKYGIDAKVRHEVTKVDTEKKMVYAEHTKTKDVFEFP
                     YDRLLIATGVRPVMPEWEGRELQGIHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNER
                     VEAIETDKGTYKADLVLVSVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLART
                     GLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            8093..8581
                     /locus_tag="YBT1518_RS07570"
                     /old_locus_tag="YBT1518_07295"
     CDS             8093..8581
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135035.1"
                     /locus_tag="YBT1518_RS07570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07295"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_023521444.1"
                     /transl_table=11
                     /translation="MIVALQKVQESEKEILRNLYALYLHDLSKFTMNITIGANGFFEYE
                     DLHMFWKHDGITPYFIKIDHSIVGFLLLLERPFLKKENDFGINDIFILNQYKGKGIGKQ
                     VVENLLEEKRGQYFVIELLKNVPAVSFWKKVYKELNIEFDEREQLIDAEECLVQTFKI"
     gene            8878..9288
                     /locus_tag="YBT1518_RS07575"
                     /old_locus_tag="YBT1518_07300"
     CDS             8878..9288
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="YBT1518_RS07575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07300"
                     /product="DUF3908 family protein"
                     /protein_id="WP_023521445.1"
                     /transl_table=11
                     /translation="MAINMKTIEEWIVESNTRHEEDFGHVVEEMNEVCVGLDNATLIYT
                     KNVFCFGKKVEVFFFFQDHVVIGQEKDEYIEIEKLKYDDITNSNLKTNDKNTTLELKFA
                     NGQSINLDSLNDNYGTKNWLFARQIKSIFKLI"
     gene            complement(9319..9909)
                     /locus_tag="YBT1518_RS07580"
                     /old_locus_tag="YBT1518_07305"
     CDS             complement(9319..9909)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-149). E-value: 6.4e-13. Score:
                     39.4. Matches aSDomain:
                     nrpspksdomains_YBT1518_RS07580_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016109564.1"
                     /locus_tag="YBT1518_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07305"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000025748.1"
                     /transl_table=11
                     /translation="MSILQRLIQQAKNPSGTIGSSMLCIMNAAHTRLINWALQKVHIKT
                     DAVVLDIGCGGGKTIHTLSKRTPLGGIYGIDYSDQAVKNSIQTNAKDVQKQKVIVQQAS
                     VSSIPHHTNFFDLITAFQTHYFWPDIEQDIKEVFRVLKPDGSFLLVAETFKIQYHMEKF
                     KTNEELINLFYKTGFTKVQCYEEKGCLCVIGNK"
     aSDomain        complement(9463..9765)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_YBT1518_RS07580_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.40E-13"
                     /label="YBT1518_RS07580_oMT.1"
                     /locus_tag="YBT1518_RS07580"
                     /protein_end="149"
                     /protein_start="48"
                     /score="39.4"
                     /tool="antismash"
                     /translation="VLDIGCGGGKTIHTLSKRTPLGGIYGIDYSDQAVKNSIQTNAKDV
                     QKQKVIVQQASVSSIPHHTNFFDLITAFQTHYFWPDIEQDIKEVFRVLKPDGSFLL"
     gene            complement(10001..11542)
                     /locus_tag="YBT1518_RS07585"
                     /old_locus_tag="YBT1518_07310"
     CDS             complement(10001..11542)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016124293.1"
                     /locus_tag="YBT1518_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07310"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_023521446.1"
                     /sec_met_domain="PF00881 (E-value: 9.9e-09, bitscore: 33.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLDTFLHHLHFSIDEIMPNHEVDWKDAPLPYKLYRNVPTIPLSL
                     EIPLSLPNSSTTPTLDEIGHYLWYSFGVTQLCQLNSERNVLRRSIPSGGALYPNELYIY
                     LKIDDYPDGIYHYDVAHHRLILLREGNFDSYLADALGNRCNIHDCFGAAFVSTMFWKNF
                     FKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRALNHLLGLSEGEESVYA
                     VIPLSTESETNWFHNDYRENKTVTSHEFLQQIPPLAHEHFVRSKHVNEHPMITKINEAS
                     MIESTEHFQTLHHEEHYQHNTYAVQLPKVERLSYDFLQLCKKRYSPDADFILTKWDAAE
                     LATLLQEASLSFLYYNDLDGKYINENARVSLYGCFYNVKNIKNGAYAYNSKTHSIQPIR
                     YGDLRYPLQSSMTMDNVNLFQVPLCLHVVGKKDYYTRALGYRGYRIHQMEAGILVHKLV
                     FAATAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQVPVGAYRARNWLKGALHN"
     gene            complement(11558..13507)
                     /locus_tag="YBT1518_RS07590"
                     /old_locus_tag="YBT1518_07315"
     CDS             complement(11558..13507)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="YBT1518_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07315"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_000197742.1"
                     /sec_met_domain="YcaO (E-value: 8.8e-84, bitscore: 280.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.2e-141, bitscore:
                     470.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRNILLIGDGLLADYVHDQLCEQYSIIRQHTITEELPENIHLAL
                     VLHDGSPSTIHHDAELIFRSNHIPWLRGFTSFGEGIIGPYIHPLSSGCSHCSDGRRFIA
                     GFDQQEMWELQRKYAFKADNVTRRDVRATQNGMLQMCHLIRVETEKILTHNHSSLENEL
                     ILLNLQTLQCTRHSFLPDPLCPICSNLPDDTADAAELSLQPSLKVSTETYRCRSIHELN
                     TFLTRDYLDYRVGMLNGKMQHSLLPFADVIINMPLMFGNEGVAGRTHSFAVSEATAILE
                     GLERYCGMSPRGKKTNVHGSFHDLEEHALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLSQNRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMIQRLRMITGYELHAFNATMEHGIPSLWVIAK
                     NTRENGMNVVCAGGAHLDPIRALKSAIQEIAGMLLITDDELEHKREYYEKCLQDPYFVN
                     KMEDHSMLYGLKETEERLHFLLRENAPVQTFQEMNVSQSFDMDLTSDLHQLLNRLHQSE
                     LEVIVVDQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYTDEP
                     LTNERLNPHPHPFP"
     gene            complement(13504..15423)
                     /locus_tag="YBT1518_RS07595"
                     /old_locus_tag="YBT1518_07320"
     CDS             complement(13504..15423)
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="YBT1518_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07320"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_023521447.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1216.8,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     7.1e-55, bitscore: 181.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 4.8e-11,
                     bitscore: 41.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGAGIYDW
                     IEKLMPMFNGNYSLAEITDGLPLPYQNRVFEIGEILYENGFVRDTNQDEPHELNSTLLD
                     RYASQIEFLEADSHSGALKFETYRGANVLVLGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     DETNYDRIHELIERAYEVDNTVLLQEIDTTIDRPLHEVFEPFDWILYVSQNGDIDGLKT
                     VHTICREAKKNFIPAICLSTLGIAGPVVTENRDECWESAWHRLHETTLQNENSSDSFSP
                     ITSAMLANVIVFELFKHVADDSHREKGSQFFLLNYETLEGTWHPFIKHPLATDESFRID
                     TIENLSEKLEHRSNQHTSTDVFQFFDSLTSKEAGIFHVWDEQDSYQLPLSQCYIQVANP
                     LSDGPAPLLPLMTCSGLTHNEARREAGLTGIETYVAEIIHRLIPEHNDIGIGAGETMTE
                     GFYRALQQHLNNKLYERQSHTLEELTTIDLTDIHDKHCRFYYDALSTIHETPTIAMSEE
                     ILSFPVVWIGINDRWYGASNINMTLALRNALQLALFHIQNEEIPYRANILYDSSIILYD
                     TDSFRVEIQPEEEIPNVQSLQLALQHLEEHNFYPFVFDLAIEPFLKENLDGVYGVLIAK
                     EDGL"
     aSDomain        complement(15124..15423)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_YBT1518_RS07595_Heterocycloanthracin_
                     C_RRE.1"
                     /evalue="3.30E-57"
                     /identifier="RREFam011.1"
                     /label="YBT1518_RS07595"
                     /locus_tag="YBT1518_RS07595"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.5"
                     /tool="antismash"
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGAGIYDW
                     IEKLMPMFNGNYSLAEITDGLPLPYQNRVFEIGEILYENGFVRDTNQDEPHELNS"
     aSDomain        complement(15157..15393)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_YBT1518_RS07595_Thiopeptide_F_RRE.1"
                     /evalue="2.20E-13"
                     /identifier="RREFam004.1"
                     /label="YBT1518_RS07595"
                     /locus_tag="YBT1518_RS07595"
                     /protein_end="89"
                     /protein_start="10"
                     /score="41.0"
                     /tool="antismash"
                     /translation="KVNKDTFFLPDSNGGVYFRNNASSFRMDGAGIYDWIEKLMPMFNG
                     NYSLAEITDGLPLPYQNRVFEIGEILYENGFVRD"
     gene            complement(15548..16807)
                     /gene="odhB"
                     /locus_tag="YBT1518_RS07600"
                     /old_locus_tag="YBT1518_07325"
     CDS             complement(15548..16807)
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="YBT1518_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07325"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_000569892.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESITEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAPVAVSTPAPAAEQPKQETAEAPKA
                     AAPNAEQTTGLQGLPNTNRPIASPAARKMARELGIDLNDVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKSPAPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVD
                     MSAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYD
                     IGIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGMKARDNKLSLKELQGGTFTITNGG
                     VFGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAV
                     SFLVAVKDMLEDPKSLLLEG"
     gene            complement(16940..19807)
                     /gene="odhA"
                     /locus_tag="YBT1518_RS07605"
                     /old_locus_tag="YBT1518_07330"
     CDS             complement(16940..19807)
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="YBT1518_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07330"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_000197138.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYTHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEIETITQFTQEQLKSDYA
                     QVPPADTSDATIHVKVPDVVAKGIQPIDTGVELDSLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGT
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKLEIEVFSN"
     misc_feature    complement(20221..20241)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.69"
                     /tool="antismash"
     gene            20632..20841
                     /locus_tag="YBT1518_RS07610"
                     /old_locus_tag="YBT1518_07335"
     CDS             20632..20841
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428510.1"
                     /locus_tag="YBT1518_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07335"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428506.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGE"
     gene            20844..21221
                     /locus_tag="YBT1518_RS07615"
                     /old_locus_tag="YBT1518_07340"
     CDS             20844..21221
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="YBT1518_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07340"
                     /product="hypothetical protein"
                     /protein_id="WP_023521448.1"
                     /transl_table=11
                     /translation="MNYSQKYFVIMGIIFLFMSGFMILTGIMTHSAPPSPTYTLLAMMV
                     MCFYLSYLHPQFKEKDERMKLIRYKGMFFSFFALTAYYLLFSIGLNLKILTLSATELLN
                     ILMALTMSTVFISFVVLAKRY"
     gene            21250..21432
                     /locus_tag="YBT1518_RS07620"
                     /old_locus_tag="YBT1518_07345"
     CDS             21250..21432
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="YBT1518_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07345"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_001178297.1"
                     /transl_table=11
                     /translation="MQMMYAFGIGLVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVIM
                     FIAIIVMIVLISRSL"
     gene            21566..21928
                     /locus_tag="YBT1518_RS07625"
                     /old_locus_tag="YBT1518_07350"
     CDS             21566..21928
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036573.1"
                     /locus_tag="YBT1518_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YBT1518_07350"
                     /product="hypothetical protein"
                     /protein_id="WP_023521449.1"
                     /transl_table=11
                     /translation="MNKKTIFYLLTCLLLVASTTYIICNKREQVPPMLVWDEQEYYVTN
                     ESAKIEEVGQKLGEVTKKIKTSKKPTKNKESNKLQEKTEVFTMIEEEKDPQSPLIIKET
                     YSDEYRVVRPMLKQVL"
     gene            21957..22209
                     /locus_tag="YBT1518_RS34470"
                     /pseudo=""
     CDS             21957..22209
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126037.1"
                     /locus_tag="YBT1518_RS34470"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSYPWVLRKTFFLCFILSPYRCRLHFDE"
     gene            22297..22443
                     /locus_tag="YBT1518_RS34475"
     CDS             22297..22443
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017793.4"
                     /locus_tag="YBT1518_RS34475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_080546092.1"
                     /transl_table=11
                     /translation="MKVTPERLEQTAKTVNNIRHFLEYLHNDLYNQIKNIAIQWNGASR
                     EQF"
ORIGIN
        1 atcattgagc ttttagaaac tgaaaagcga gaagaaatat gtgaattaat atatgcaaca
       61 aaacaaaaag aagaggcgta gtctcttctt tttgttttgc gtaataaatg ttaaaatata
      121 cagaaaatac atgtaattta gagggtgaga agacatgcta agacggaaat tactatatct
      181 tcttttaact gtaccactat acgcttggct cattagcatg acgaaaatag agttgatggc
      241 tctattttta ggatatgtat ttatcttttc caacttaaat cgcattcaag aacagtctat
      301 tttagaaata tgtctatttt cgattagtat agaattattt agtatcgttt cgattgtatt
      361 attaaacgaa ttatttctac ggattcattc atttacatta atgaaatttt ggaatattgc
      421 attgcaagca atatgtactt acattgtgtt tgttgtgttg aaaaaaataa tcggacagca
      481 gacagttttt caggataata gaaaatggga gtgaatgaaa aggggccgtt tggctccttt
      541 tttaaatctg ttttaaaaac aattgaaaat cacaacatct gttatataat agttaaaaat
      601 tgtattttaa acgaaatgag atgataacat ggccatattg ttggcactta tcccaattat
      661 gatgattttc atttgtttat ttttatttaa acaaacgtca ttaaggtctg cgttaatttc
      721 ttatgctgta tgtgttggaa tcgttttact ctcgccaacg tttcaattag ggataagtga
      781 aactcttcac gcaacgatta aaggttggtt aatttgtttt attgttgggt acgttttgtt
      841 tttcggtatt tttttatttc acctcatgaa caaaatggga tacatcgatc aagtagcgcg
      901 ttttttagaa gaagtgacgc acgatcgttt attacaaatg ctccttatgt gttttggtat
      961 ttgtccgcta attgaatcag taagtggatt cggaattggc ttcatggttg cagcacctat
     1021 ctttctatca ttaggttata aaccgtttca agctgtacta ctttcattta ttggtttact
     1081 agctagttca tggggcgcaa tggcaactgg tacgattatc ggttcgcagc taataaatat
     1141 gcctcttaca acacttggta caaatacagc gctattaagt attccgatgt ttgcttactt
     1201 tgttattctt tctttatacg ttgttggcgg ctggcaagca gttatagaaa agtggaaaga
     1261 aggagtagga ttctttctat tattttctct cggaatctat ctttctaatg cgtacgtaag
     1321 tgttgaacta gccgggatat taagttctat cgttacgatt acatttggtt ttcttatcat
     1381 taaattaaaa ggaaaaagtg aacaaaatct aataacagag catgcggctg caacggagag
     1441 agaagtatcc attataaaaa ttattagccc ttatatattt ctaacagttt gtattttact
     1501 ttctcgcctg gttccagcat tacatgattt gttcagatca tatgcggttc ttgatttgaa
     1561 atcatactct tacaaactag agttactata ttcaccagga ttttggctcg gtatgacttg
     1621 cttatttact attattttct tccgcatccc gtctaatatt attaaacaat cactctcgca
     1681 aacgatcaaa caatggattc cttttgctat tactacgaca atgtttatcg ccatttcaga
     1741 attaatgggt gcatcaggca tgcatttatt actcgcaaag atagctggtg aaacatttgg
     1801 aacctttttc gttttctttg ctccgtttat tggcgctatt ggtggatttt taacaggtag
     1861 taacgcagga tcaaatgcaa tgtttataaa actacaaatg caaaccgcac aaaacgtagc
     1921 actcccgtgg caatacgtca caacactgca aaacaccgca tcatcagtag cgacaatcgc
     1981 ttgcccgtca cggattacac taggtgctta cttatgtaat atcccttacc gtgaaaatga
     2041 actgttaaag aagacaacgt taatgatctt tggtgcggtt ttgcttgtaa tggtagaagt
     2101 tatcgtttgg tatatgttga gaaattaaaa atcctcctaa cataggagga ttttttttat
     2161 gagtggataa tgatttaaat atgaatagct tctactaaat gaataggaga tgaaatgtat
     2221 gcccttaaaa aactacggtg tgttaaaagg tacagttata caatcaaaga ttggaaaagg
     2281 gaaaacacct cattatcaag ttcatttaca gggcgagact ggagtagatt atcgtattgc
     2341 tattaacgta aagtcgcaaa gttatccgtc agaagtttta tattttgcga gtaacaatat
     2401 taggtcagag gcgattcata ttttaccgac attaccattt ggttttacgg aagtaaaaaa
     2461 caatgaaccg aaagtagctt tagattatgt aagaggaaat ctatttgact caaaacaaat
     2521 gattcctttg cctcccgaaa aagcaggagc agataatgat ttaaacgaaa aaatagaacg
     2581 ttatataaag cgagcgatgg aagaaaaagc aattatttat gcgtttggcg aaagatgggg
     2641 accagaagaa aacacaccag attcctattt tcatttcaaa ccaggaaacg gtatacatga
     2701 tattcacatg aatcaaggga atgtagaaaa atggcaaggt gatgatggca tatggcaaga
     2761 tggaggaata cttattcact ttgaaaagga agaagaatgg atcggtatct ttcttgcctt
     2821 ccaatcacag tcatggtgta ccgatgaaga ggggcatgct cgtgtgcctg ttgagcattg
     2881 tgattataag gggaataatt aataagaaga gggcgttcaa aaagaacgcc ctcttcttat
     2941 tttataaaac gaaaaactaa cgagtgtaga aagacaagag aacagcagtg ccacactaga
     3001 aaacgcaatg agatacatat tatatttcat aacctgtcca attagctgat tactgtcgta
     3061 ttgaaacagt cctgctatta tgttgaataa aaataacacg ataaacatga cgacaacacc
     3121 gtctattgat tctttaatgt ctggtttact taaagcgata tgtgcggaaa tgcaaatggc
     3181 gataaataaa aataaccaaa aggaaggatt caataaattg ccgattgtaa ataagctttt
     3241 caataataca aacgtcgaca agagcatgtt ttgaatcatt tctacattaa tagaagtaga
     3301 agcaatcgtt ttttcgagag ttgtattaaa taaaaaatat gattctggta cgaaatagcg
     3361 cattaaaagg attaatgcag taataccaga aataataggc ccaatgccga taaagaaatt
     3421 cccaattcgt tgatacacac ttttttgatt gtattgatgt tgtatataac ctaaagcccc
     3481 ttgacttgta tctgttggga agaactgagt cgccacaatt ttatgacgga acagtacgca
     3541 cataatggca tgtccaagtt cgtgaatcgg aacaccgatc caagccgtta ataggaatcc
     3601 ttttcttcca aaagctctcg accaatacat gcgtgtgaga gattctaaat agcctaatag
     3661 aaatccaatt acaatgataa cgccaattaa agataataat tggattacgc ttgtaaggag
     3721 tatttgaaaa attgagttta ccaatgccat tttctttcat ccaatctgtt aaaaatatta
     3781 tttattctgt ttcataatag catttttttt caagattgct agcacatata ttttctttcg
     3841 gaagaaggat ttcagaatct ttttcttgta gtcatgtttt atgtacaaat tcatatattg
     3901 aacttgtaac accctataag gtatatgctt aaggagggat aagagaatga aatgtccgtc
     3961 atgtcataca aaaaatgcag tagaggcaaa gttttgcggg aattgtggac attcgttaac
     4021 ggaagaagta gtggtaagta gtggccaaga agaagggccg gaacaagcac gtgcggcaca
     4081 agcaaaggaa gctcggccaa atgaaacggt agagcaagcg aagcggtttg cgagcggcta
     4141 ttttcaattt tttaaacatg cattacaagc accgacagcg attatgaaaa gcggcgctat
     4201 tgaagtgcga aatggaatta taagtcttgt tcttatttgt tttttaggag catgtatttt
     4261 ttatagaatg atgagtgcag catcagcagt tacgagaaca tttgcaccag atatatctac
     4321 tcccacgttt tttggagaat ctataacggt ctttttcttt ttattaattt taactttatt
     4381 tgtcggattt attatttttg taagtggtaa gatgatgaaa tcatcttttt cgtttcttga
     4441 agtatttggt atatggggaa cgatagcaac gccggctatt gtcatattag ttctttcttt
     4501 tctttttagt tttttattaa tctttttctt accgatatta ttatcggtag ttgcaactta
     4561 tatagggatt agtataactg tagccgtatt aaaactagac aatggcggat tagatctcgt
     4621 ttacacactt attattgcaa atgttttaat tggaattgca acgttcattg tactttggtc
     4681 ttacattagc acgataattc aagccttaac acagggaata actggcttct aatgaaaagg
     4741 tggttgactg aatgaatgta tgtacaaagt gcggagttca gtttgaagat ggtgtgcaat
     4801 tttgtcaaaa ctgcgggatg aagaggggaa gtcctgtagt aaagaagaac atgagcagtg
     4861 gtacaaaagt tggcattaca ctgttagcac tatttgttat agcgattatt ggattgtatt
     4921 tgtacggatc atcgtattat acgcaggtgg cacaagtaga ccggatgatt acgattttac
     4981 aagagcggga cggagagaaa ttagctgaga tcgttacggc agatgatcca tcggttatga
     5041 taacgagaga gaatttaacg cctctatttt catatataaa agaaaatcca gcttacgtaa
     5101 atgaattaaa agaatatttg agacaaggtg aaaaacaacg ggacggaata gaaagagctg
     5161 atttttcatt aacgaaagac ggaaagtatt tctttatatt tgatcggtat aaattgaaag
     5221 cgaagacata ctatacaact ttgcttacaa atgaaaaagg cgtagcgtta aaaatgaacg
     5281 gaaaagaaat tgataagaca gatgacaaaa agtttgagaa gcaatatggg ccatttcttc
     5341 cgggaaatca agtgtttcaa tcagaatata aaaatgacta tgtaaaacta tctcgtgagg
     5401 aaaaggttgt acttatgaaa caaagccaaa ataacgtaac gatagattta acgttgcaag
     5461 gtcaatatat tacagttcaa acgaacgcgc ctggtgcaac attgtacgta aatcaaaaac
     5521 cggttacagc gctcgcagga gaagcaatta catgggggcc tgtagcgact gatggaagcg
     5581 cgaaaattta tttagaacga aatggagaaa atggacggga aacgacaaaa ttagagacgg
     5641 taacggcact ttcgtcttat aatcttccat tccaaacgaa aagtgcagaa aaaacagttg
     5701 tttataatgt tactccaacg cccgcgactg ggtatgtata taatggtttc atctttcctg
     5761 atagtgatat tcgaaaatta acgagcacag atttaaccta tttatcgaaa gaacagttga
     5821 aaattgctag aaatgaaata tatgcaaggc atggacatat ttttcaaacg aaagatatgc
     5881 aagcgtattt tgcaaaacag tcttggtata gagaaaatcc ttactttaca ggaacgttaa
     5941 cagatattga aacttataat attgaactga ttaaatcaag agaatagaac acatgaaaaa
     6001 aggtacggtg cataactgta ccttttttat ggtttttttt tatctgaacc aggatccctt
     6061 gagaaaaaga tatgaaagag gaatgtgact ttacttgctc ctcctgatgt acttgcttgc
     6121 acgtcagata atgcgttaga tgttaaaaca ccttcagaat gagggggtac gactattttg
     6181 agagtatcat ctgattctga tgatgcagta actgttattg tatcatcaga taagtttaaa
     6241 atttttacag taccgattgg taagatggac ttgccagcgt gtgatgctga agcaaagcga
     6301 gagcctttcc aaatcgtttg tggaaaagtt tcatcattag ataaccaagc acgagcacta
     6361 taaatggttg cgttaataga aaattcttga tcaagcgaca aggcgggttt tggttctttc
     6421 ggttcctctg gaaactgagc gagaagacca gcgcacatgt atatttcacc tactttcaat
     6481 tggttactgt tatagcatat taaacatgtt gtttataaga cacgacagtt acctattcat
     6541 acataagttt gtgcaccaaa tttgaagatg aaattctctt tctttacaat ggaagtaggt
     6601 gttatttcta taaaatatgg aaaacgtaaa gagtatgtaa aaaagaagga gtggtaaagt
     6661 gaactatgtc attattggcg gagatgcagc tggtatgagt gcagctatgc aaattgttag
     6721 aaacgatgaa agtgcaaatg ttgtaacttt agaaaaaggt gaaatttatt catacgctca
     6781 gtgtggatta ccgtatgtca ttagtggtgc tatcgcttca actgaaaagt taatcgcgcg
     6841 caacgtaaag acgtttcgtg agaaatatgg aattgatgcg aaagtgcgtc atgaagtaac
     6901 gaaagtagat acggaaaaga aaatggtgta cgcagagcat acgaagacga aggatgtctt
     6961 tgaatttcca tatgatcgat tattaattgc gactggagtg cgtcctgtta tgccagaatg
     7021 ggaaggacgg gaattacaag gcattcatct tttaaaaaca attcctgatg ctgagcgcat
     7081 attaaaaacg ttagaaacga ataaagttga agatgtaacg attattggcg gtggtgcaat
     7141 cggactagag atggcagaaa cattcgtcga acttggtaag aaagtaagaa tgattgagcg
     7201 aaatgatcat atcggtacga tttatgatgc agatatggct gaatatatac ataaagaagc
     7261 agataaacac aatattgaaa ttttaacgaa tgaaaatgta aaagcattta aaggaaatga
     7321 acgagtagaa gcaatcgaaa cggataaagg tacgtataaa gcagatcttg ttttagtgtc
     7381 ggttggagtg aagccaaata ctgattttct tgaagggaca aatatacgta agaatcataa
     7441 aggagcaatc gaagtaaatg catatatgca aacgaatgtg caagacgtat atgcagccgg
     7501 tgattgcgca acacattacc acgttataaa ggaaattcat gatcatatcc cgctcggaac
     7561 gacagccaat aagcaagggc gacttgctgg actgaatatg ctggataaac gaagagcttt
     7621 taaaggtacg ttaggcacag gcattattaa atttatggat ttgacgctcg caagaacagg
     7681 gttaaatgaa aaagaagcaa aagggctaca cattccgtat aaaacggtca aagtagattc
     7741 tacaaatatg gcgggctatt atccaaatgc aaaaccactt tacttgaaat tactatatcg
     7801 ctccgatacg aaacaattat tgggcgggca agtaattgga gaagaaggcg tagataaacg
     7861 tattgatgtg atcgcgatgg cacttttcaa taaaatgagc attcatgatt tagaagatgt
     7921 cgatttaagt tatgcaccac catataacag cgtttgggat ccaattcagc aagcggcaag
     7981 gagagcagaa tagcactttt taaagtgcta tttttttgtt aaaggggaat tatcattttt
     8041 gtcgaatgaa gaggatcggg aaatagttac atatgtggaa ggggagtttt ttatgattgt
     8101 agcacttcaa aaagttcaag aatcagaaaa agaaatatta cgtaatttgt atgcattata
     8161 tcttcatgac ctttctaagt tcactatgaa tataactatc ggagcgaacg gtttttttga
     8221 atacgaagat ttacacatgt tttggaaaca tgacggaatc actccgtatt ttataaagat
     8281 tgatcatagt attgtagggt tcttattact actggaacgt ccgtttttga agaaggaaaa
     8341 tgattttggt attaatgata ttttcatatt gaatcaatat aaaggaaaag gaatcggtaa
     8401 acaagttgtt gagaatttac tagaagagaa acgaggacaa tatttcgtta tcgaacttct
     8461 aaaaaatgta ccagcagttt cgttttggaa gaaagtatat aaagaactga acattgaatt
     8521 tgatgagaga gagcagctaa ttgatgctga agaatgcctc gttcaaacgt ttaaaatata
     8581 atgaaattgg tgctactttt atattacttt gaaatttaac tttatcccgc tatttgcgga
     8641 cagtaagacc cccacctcaa aatccagtga aagcaaagaa gttaggtggg ggatcaactg
     8701 cccgtaaaag cccgattggt tcaactaata atcagtgggg atgaagaccc ctattgatta
     8761 aagtttcact ttattttgaa tataccgttc ccccttgaaa acatattact aatcgcttat
     8821 attttcatat agtatttatt ttttaaacga agcaatgaac gaaccagggg gcgcagtatg
     8881 gcaattaata tgaaaacaat cgaagaatgg attgttgaat caaatacaag acatgaagaa
     8941 gactttggac acgttgtgga agaaatgaac gaagtatgtg tcggacttga taacgcgaca
     9001 ttaatttata cgaaaaatgt attttgtttc ggtaaaaaag tagaagtatt tttcttcttc
     9061 caagaccatg tcgtgatcgg acaagaaaaa gacgaatata ttgagattga aaaattaaag
     9121 tatgatgata ttacaaatag taatttaaaa acaaatgaca aaaatacaac gttagaatta
     9181 aagtttgcta acggacaatc tattaattta gatagtttaa atgataacta cggtacgaaa
     9241 aattggttat ttgctagaca aattaagagt atttttaagt taatttagta aaaagcaggc
     9301 ccataaaggt ctgctttttt acttatttcc tattacacaa aggcaccctt tttcttcata
     9361 acattgcact tttgtaaatc ctgtcttata aaataggttt attaattctt catttgtttt
     9421 aaatttctcc atatggtatt gaattttgaa agtttcagcc actaataaaa aggagccgtc
     9481 tggttttaag acgcgaaata cttcttttat atcttgttca atatcaggcc aaaaataatg
     9541 agtttgaaag gcggtaatga gatcgaagaa gttcgtatga tgtggaatag aagaaacgct
     9601 tgcttgttga acaattactt tttgtttttg aacatctttt gcatttgtct gtatagaatt
     9661 tttcacagct tgatcggagt aatcaatccc atatattccc ccaagtggag ttcgttttga
     9721 aagagtgtgt atggttttgc ctccaccaca gccgatgtct aatacgactg catctgtctt
     9781 tatatgtact ttctgtaatg cccaatttat taatctcgta tgtgcagcgt tcataataca
     9841 aagcatggag gaaccaattg ttccgctagg attttttgct tgctgaatta atcgttgtaa
     9901 aatgctcaag tcaaactctc cttttatgta agaatatata ctcatttcgc tttttataaa
     9961 ttaaatcctt taaaaaagca cgccgataga cggcgtgctt ttaattatgc aaagcccctt
    10021 ttaaccaatt ccgcgcccga tatgccccaa ctggaacttg aataagagac gtttcattcc
    10081 cagcatcaat tccgtacaat tgatcacatg aatttgtatc aaaacttagt aacggatgcc
    10141 cgcccatccc catagcagtt gcagcaaaaa cgagtttatg aacgagtata ccagcttcca
    10201 tttgatgaat acggtatcct ctatagccta atgcacgtgt atagtaatct ttctttccaa
    10261 ctacatgtag gcaaagtggt acttgaaaaa ggtttacgtt atccatcgtc atactagact
    10321 gaaggggata acgaaggtct ccataacgaa tgggttgtat ggaatgtgtt ttactgttat
    10381 aagcgtaagc cccgttttta atatttttca cgttataaaa acatccatat aaggagacgc
    10441 gtgcattttc atttatatac ttgccatcaa ggtcgttgta atagaggaag gagaggctcg
    10501 cttcttgtag taaagtagcg agctcagctg catcccattt cgttaaaata aagtccgcat
    10561 caggagaata tcgtttttta caaagttgta ggaaatcata cgataaccgt tctactttcg
    10621 gtagctgtac agcgtacgta ttatgttgat agtgctcttc atgatgtagt gtttggaagt
    10681 gttctgtcga ttcaatcata gaagcttcat ttatttttgt tatcatcgga tgttcattta
    10741 catgttttga gcgaacgaaa tgttcatgtg ctaacggcgg aatttgttgc aaaaactcat
    10801 gagaagtaac tgttttattt tcacggtaat cattgtgaaa ccaattagtt tctgattctg
    10861 tacttaaagg aataacggca tacacacttt cttcaccttc tgacaatccg agtaaatggt
    10921 tcagtgcacg gtctagaaac tgaaagtata cgccgttcgt ataaccgaac tgttttgcac
    10981 attctagtaa ttgtccaatg agaactccgc tatctaatcc ttgaaggcga tatgaaaaat
    11041 tattgtattt aaagaaattt ttccaaaaca tagtggatac gaatgcagca ccgaaacaat
    11101 catgtatatt acagcgatta ccgagtgcgt ctgctaaata agaatcgaaa tttccttcgc
    11161 gaagtaaaat aagtcggtga tgtgcgacgt cataatggta aatgccgtct ggataatcgt
    11221 caatttttaa atagatatac aattcattcg gatataaagc gccgcctgaa ggaatggatc
    11281 tgcgtaatac atttctctcg ctatttagct gacataattg tgttacacca aatgaatacc
    11341 aaaggtagtg accaatctca tctaaagtag gtgtagtaga agagttcggc aaagataacg
    11401 ggatttctaa ggaaagcggg atggtaggta catttcgata taatttataa ggaagcggtg
    11461 cgtctttcca gtccacctca tgattcggca taatttcatc aatagagaaa tggagatgat
    11521 gtaaaaaagt atctagctgc atgaaatccc tcctttacta tggaaacgga tgtggatgtg
    11581 gatttaacct ttcattcgtt aaaggttcgt ctgtatatcc aagtgtcatt ggtacagtat
    11641 atacccggtc cagtcctgta acccgagtaa gatggtgacc gaacgtcatc ggtagcatgc
    11701 ctggaataat gacttttaca cagtgtagtc cgttcttttc tataaggggg acggtttgat
    11761 ctacaacgat tacttcaagt tctgattgat gcaaacgatt taaaagttgg tgaagatcgg
    11821 atgttaaatc catatcaaat gattgtgata cattcatttc ttggaacgtt tgtaccggtg
    11881 cattttctcg taaaaggaag tgaagacgtt cttccgtttc tttcaatccg tacagcatac
    11941 tatggtcttc cattttatta acgaaataag gatcttgtaa gcatttttcg tagtactctc
    12001 ttttgtgctc gagctcatcg tctgttataa gtaacatgcc tgctatttct tgaatggcac
    12061 tttttaaagc tcgaatagga tctaaatgag cgcctccagc acaaacaacg ttcattccat
    12121 tttcacgcgt attttttgca attacccata agctcgggat gccgtgttcc atcgtcgcgt
    12181 taaaagcgtg taattcatac ccggtaatca tacgtaaccg ctggatcatt aattgtaatt
    12241 ccgtatcatt tgctgaacta agatcaaggc ggggaagagg taattcggca taccaagtga
    12301 gtaagaaggc atcacgctct acaatttcta aaataccgtg aaaaattgct tcttctaaac
    12361 taccaccaat tgcacatcca tttgatgttt catacacgaa agcatctcga tgaccgaggc
    12421 tgtaataagc aattgattca ggaactaaaa gcggtctgtt ttgtgataaa gaatatcccc
    12481 atacccagtt ttgctcataa tcaggatcaa acggcttaaa tggaaaacta tcgcgattgt
    12541 aatgttcatt ggtatgtaca ccgagtgtga ggggattcag tgcatgttcc tctaaatcat
    12601 gaaaactacc atgcacattt gtctttttcc cacgaggcga cataccgcaa tatcgttcta
    12661 aaccttctaa aatagcagtt gcttcactca ctgcaaatga atgagttcgt cccgcaacac
    12721 cttcatttcc gaacattaat ggcatgttta taatgacatc agcaaatggt aataaagaat
    12781 gctgcatttt gccgtttaac ataccgaccc gataatctaa atagtctctc gttaaaaatg
    12841 tgtttaactc atgaatggaa cgacagcgat acgtttcagt acttactttt aagctcggtt
    12901 gtaaagaaag ttccgccgca tccgcagtat catcaggtaa attactacat ataggacaga
    12961 gaggatctgg aagaaaagaa tgccgcgtac attgtaatgt ttgtaagttg agtaaaataa
    13021 gttcattttc taaagaagaa tggttatgag ttaatatttt ctctgtttct acgcgaataa
    13081 gatggcacat ttgtaacatt ccattttggg tggcgcgtac atcacgcctc gttacattgt
    13141 cggctttaaa ggcgtatttc cgctgtagtt cccacatttc ttgttgatcg aagccagcga
    13201 taaatcggcg tccatcagaa caatgagaac agccagatga aagaggatga atgtaaggac
    13261 cgataatacc ttcgccaaat gaagtgaaac cgcgaagcca cggaatatga tttgagcgaa
    13321 aaataagttc agcatcatga tgaatagtag aaggagatcc gtcatgtaat acgagagcga
    13381 ggtgaatatt ttcagggagt tcttctgtaa tggtatgttg gcgaatgatg gaatattgtt
    13441 cgcataattg atcatgtaca tagtctgcaa gtaggccatc tcctataagc aatatatttc
    13501 gagtcataga ccatcctcct ttgcaattaa taccccatac acaccgtcta agttttcttt
    13561 caaaaatggt tcgattgcta aatcaaacac gaaaggataa aaattatgtt cttctaaatg
    13621 ctgtaaggca agctgtaaag attgcacatt tggaatttct tcttctggtt gtatttccac
    13681 tctaaaagaa tcagtgtcat ataaaataat agatgagtca tacaaaatat tagctctgta
    13741 aggaatctct tcattttgaa tgtgaaagag tgccagttgt agtgcgtttc gtaacgctaa
    13801 cgtcatattt atattagatg caccgtacca tctatcattt ataccaatcc aaacgacagg
    13861 aaaactaaga atctcttcac tcattgctat tgtaggtgtt tcatggattg tagagagagc
    13921 atcgtaataa aatctacaat gcttatcgtg aatgtcagtt aaatcaattg ttgtaagttc
    13981 ttctagcgta tgtgactgcc gttcatacag tttattgttt aaatgttgtt gtagtgcgcg
    14041 gtaaaaacct tctgtcatcg tttctccagc accgataccg atatcgttat gttcaggaat
    14101 aaggcggtga atgatttctg ctacatatgt ttcaattcct gttaaaccag cttctcggcg
    14161 tgcctcatta tgggtcaatc cactgcaagt cataagaggc aggaggggag ctgggccatc
    14221 tgatagtgga ttggctactt gaatatagca ttgtgataac ggtaattgat atgaatcttg
    14281 ttcatcccat acatggaata taccggcttc tttagaagtt aatgaatcga aaaattggaa
    14341 tacatcagtt gaagtatgtt ggttagaccg atgctcaagt ttttcagaaa gattctctat
    14401 cgtatcaatt ctaaaacttt catcagttgc aagagggtgt tttataaaag gatgccacgt
    14461 tccttcgagt gtttcatagt ttaataaaaa gaattgtgat cctttttccc gatgtgaatc
    14521 atccgcgaca tgcttaaata attcaaaaac gattacattt gctaacattg cagatgtaat
    14581 gggtgagaag gaatcagatg aattttcatt ttgcaaagtc gtttcatgta gacgatgcca
    14641 tgcagattcc cagcattcat cacgattttc cgttacgaca ggtccagcta taccgagtgt
    14701 tgataaacaa atagctggta tgaaattctt tttcgcttct ctacaaatag tgtgaactgt
    14761 ctttaaaccg tcaatgtctc cattttgaga aacatataaa atccaatcaa aaggttcgaa
    14821 tacttcatgc aaaggacggt caattgtagt atcgatttct tgaaggagta cagtgttatc
    14881 aacttcatat gcacgttcta ttagctcatg tattctgtca tagtttgttt catcccgatc
    14941 tgtaacgagg taatgaaatg taggtaaacc agattctaat aaagaagaaa ctaaggaagt
    15001 aagcatatcc ccagaaccaa gtacaaggac atttgcccca cggtacgttt cgaattttaa
    15061 agcacccgaa tgagaatcag cttctaaaaa ttcaatttgt gaagcatatc tgtcgagtaa
    15121 tgtactgttt aattcatgag gttcatcttg atttgtatcg cgaacgaaac cattttcata
    15181 taaaatctct ccaatttcaa atacgcgatt ttgatagggg agagggagac catcggttat
    15241 ttctgctaaa gaataattcc cgttaaacat tggcattagt ttttcaatcc agtcataaat
    15301 tccagcaccg tccatgcgaa atgaactggc gttatttcga aaatagacac ccccgtttga
    15361 gtcggggagg aagaaagtat ccttatttac tttaagtttt gcatgaattg gaaggttatt
    15421 cattttaatc ctccttacgt ttaggcatac attattactt tatgtcatga aatttgtccc
    15481 gtatgaacaa aataaaaaaa ggctgtagaa tgattcattc tacagccttt aataggttaa
    15541 aaatctatca accttctaat aataatgatt ttggatcttc aagcatatct ttaacagcaa
    15601 caaggaagct aactgcttct ttaccatcaa caatacggtg atcgtaagat agtgcaaggt
    15661 acatcatcgg acggttttcc atacgttctg catcaattgc aactgggcgt acttgaattt
    15721 tatgcattcc taaaatacct acttgtgggc tatttaggat tggtgttgac attagagaac
    15781 cgaatacacc accgtttgta attgtaaatg taccaccttg tagttctttt aatgaaagtt
    15841 tgttatcgcg tgctttcata cctaaattac gaatttcact ttcgatttca gcgaagttta
    15901 attggttagc atcgcgtaca actggaacaa ctaatccatc tggagctgct actgcaatac
    15961 cgatatcata gaattttttg atgataagct cgtcaccttg aatttcagca tttaataatg
    16021 ggaattgttt taatgctgca acaactgctt ttgtgaagaa tgacatgaag ccaagacgta
    16081 catcatgttt tttctcgaaa gcatctttgc gttctttacg taattccatg atcgcactca
    16141 tatcaacttc gttaaatgtt gttaacattg cagatgtttg ttgaacttct acaagacgtt
    16201 ttgcaattgt ttgacggcgg cgggacattt tcacacgctc aactggtttt tcgaattcag
    16261 tttttgcaac tggagcagga gctggactct ttggagcagc tggtgcttct tttggtgctg
    16321 cagcatgagc ttgtacatca tgtggtctca cgcgtccaag tggatctgtg ctacgtacgt
    16381 cgtttaagtc gattcctaat tcacgagcca tttttctagc agctggtgat gcaataggac
    16441 ggttcgtatt tggtaagcct tgtagacccg tagtttgttc agcatttgga gctgcagctt
    16501 tcggtgcttc agctgtttct tgttttggtt gctcagcagc tggagcaggt gtacttactg
    16561 caactggtgc tccattagca tctaaaattg cgatagttgc gccaacttca actgtatccc
    16621 caggttcgcc tagtaacttc gatacaatac ctgaatcttc tgcaatgatt tctacattga
    16681 ctttatcagt ttcaagctca acaacgctgc cacctttctc aactttgtcg cctacgttga
    16741 taagccattg tgaaatagtt ccttcggtaa tagattctgc aagctcaggt actttaattt
    16801 cgatcatttt aaatgtcctc cccttatttg cctaacggtg tgttttttct tcttttgtct
    16861 tcggtaatct ccatttgtta gcctgaccct gggcagaata tctgcccggg atcaagctag
    16921 aaaccgtcat tgttactttt taattgctga aaacttcaat ttctagttta tcttgacgga
    16981 agttatactt cacatctaaa gcgtgtgcaa caattagttc ttgctcagct ttgtgagcga
    17041 atggatcgcc gccagatggg ctagagcgat ctgggcgtcc aatgtaaccc gttttcactt
    17101 tatctccagc tagttcgaac agaattggag ccatgtaatg ccatgcgccc atattacgag
    17161 gttcttcttg aacccaaata atttcttcta agtttttaaa gcgtttaata atagattgaa
    17221 ctttctcagc agggaatggg tacaactgct caatgcgaac gacatgaacc tcatctaagt
    17281 tgtactcatg tttaccagac tcaatttctg ctgctaagtc aatcgccatt ttacctgtac
    17341 ttaaaacaag acgttttact ttgtttggtt ttgtgccaag gttttcttgt tctaaagcag
    17401 gttggaaacg tccttcgctt aactgactag cagttgaaag cgtaagtgga tgacgtaata
    17461 aactctttgg cgtcatcagt actaatggtc gaacagcttc ggttcctaag atagatgctt
    17521 gacgacgtaa aatatggaag tattgtgccg cgctcgttaa gtttgcaact gtccagttgt
    17581 tctcagcagc taactgtaag aaacgttcag gacgtgcact agagtgctct ggtccttgac
    17641 cttcataacc gtgtggtaat agaagaacta aaccagattt ttgaccccat tttgctcttc
    17701 cagctgaaac atattgatca aataatgctt gcgcagtatt tgagaagtca ccatattgcg
    17761 cttcccacat aacaagagtt tctggagcga atacgttata accatactcg taaccaacaa
    17821 cagcagcttc tgataacgga ctgttatgaa cagagaagga tgcattaatg tttggtaagc
    17881 ggtgtaatgg tgaatatgtt tcatttgtat cagtatcgtg taatacgata tgacggtgcg
    17941 cgaatgtacc acgctgtgaa tcttgaccag ttaagcgaat tggcgtacct tcttgtaaaa
    18001 tagaagcgaa tgctaatgac tcagcaagtg cccattcaat tttaccgttc tcttcaagag
    18061 catctttacg gcgctcaaga attttcttca ctttcggata tacgttaaag ccttctggcc
    18121 aagataatag accttcatta attgcacgaa gtgagtcaag ctcaacacca gtatcaattg
    18181 gctgaatacc ttttgcaaca acatctggca ctttaacgtg aattgttgca tcgctcgtat
    18241 cagctggtgg tacttgtgca tagtcagatt ttaattgctc ttgtgtaaac tgtgtaattg
    18301 tttcaatttc atctgcattt agaacaccag cagcttgtaa ttgatctgca taaattgctc
    18361 ttacagttgg gtgattttta atctttttgt acacttgtgg ttgtgtaact gctgggtcat
    18421 ccatttcgtt atgaccatag cgacggtaac caattaaatc gattaagaaa tcttttttga
    18481 acaatgtacg atattgaatt gcaaggtttg cagcagcaag acaagcttct ggatcatcag
    18541 cgttcacgtg aacaatcgga atatcgaaac cttttgcaag gtcacttgaa tatttcgtag
    18601 aacgagaatc atagctgtca gttgtaaaac caactgcatt gtttgcgata acatgaatcg
    18661 ttccgcctgt ttggtacgca ttcaatctgc ttaagttcaa cgtttcagat acaatacctt
    18721 gaccagggaa tgcagcatca ccatgaacta aaattacgaa tgattttgaa gtatcttgtt
    18781 ctggaagacc agatttttta cgattctctt gagctgcacg tgcgaaacct tctactacag
    18841 gattcacgaa ctcaagatga ctcgggttat ttgctaaagt aacgcgagtg ctaacttctt
    18901 cattactaac gacttgttct ctacctaagt ggtatttcac gtcgccagtc cagccagcat
    18961 tggctactgc gccttctatt tttgcatgtt tgaattcagc aaacatgtga gtatatggtt
    19021 tttctaatac gtgagcaagt acgcttaggc gaccgcggtg agccatacca atcatgacat
    19081 cctctacgcc gttcttagca ccttctagaa caatttcatc taaaacaggt acaagcatat
    19141 caacgccctc gatagagaaa cgtttttgcc caacgaatgt tttatgcaag aattgctcga
    19201 aaccttcaac agctgttaaa cgttttaaaa gagcagttcg ttttttattt gatagtggtt
    19261 gacgcaatga atttgattcc accatttgat gcaaccacgc gcgttcttca ctatcttgta
    19321 tatgagaaaa ttcataagct aaagattttg tataaacgtc ttttaatcta tgaattacat
    19381 caagtgcagt gtgaatacct tctggtgcat cttgccatac tgttttcgct ggaatcgctt
    19441 tcaagtctgc atcgctcagt tcgttcattg ctttctcaag aagagattgt ccgtttgcag
    19501 catcttccat cgggttgatg tgagccaacg tatgcccgaa agaacgaatc tgttcaacaa
    19561 gttgaacgac cttaagaatt ttttcaatgt tacctgtgtt ttgaggagaa aaatgtgttg
    19621 ctgtgttgtc ccctgttacg acatcatctt gaaacgaagg agctccaaaa atttcaaaaa
    19681 gctcttgtaa ttccggatca acagaacctg ctccagttac gtaaagatca tactgttcaa
    19741 taacataacc aaggttcgga ccgtggaact tggcccaagg gtttgtcgtt gtattcttcc
    19801 tcgtcatttg tttaaacctc ccaatgcata taatcctttt tccatacaaa ggtgcatttt
    19861 gctctttttc aataagtaat gaatcaataa tcaatgtaaa tgttttcttt actcttatgt
    19921 tattacaata atttacataa taccaaacac tattacttat ctgttttgta aaaaaacatt
    19981 cacaataact tatcacccaa gttaatcttt cactttataa agtaatttta cagaaaaatg
    20041 gggtggatat atttggtata cctacattaa aaactagaat tgttacatgt aaatataagt
    20101 ataatcgttg gaatgttttg ataaaagttg attagaatta tgtatattga aataataagc
    20161 gctttcatag atattataca acaatataac ggaatatagt ataaaaaata aaaaattatg
    20221 aatttagcgt aaactttatt tcgatagtgt taactatcga aaggaaaatg aaggatttcc
    20281 acaaaaaaag tggctaaaca taaaaattgc ttcataaccc gttagtttct ataaatatgc
    20341 caaaaaacac cgtaaaacca ataacgcatt tcatctaata aagaagagaa tgaaatattt
    20401 taaaaggata aaacaaatat gaagatatta aattttaaaa aaggtgagga ggaaatatag
    20461 taacgattac atacagtgtt ccaggtttta ttacaaaata gacgtgttga aatcgaacaa
    20521 gtttcttcta tataaataga gtgaaaaatg attaaaagga atgtaaagga accttgacgt
    20581 aaagtttgct ttacatatat actcgatata tgggaggagg gagaaatttc cttggaaaat
    20641 aaaatggtcg aataccgaaa aaaatttgga ctatctcaag aaaaattagc tgagaaactt
    20701 ggcgtttcaa gacaaaccat tatctcaatt gaaaaaggaa aatacgatcc gtcacttccg
    20761 ttagcatttg aaatagcaaa aacatttcaa acaacgatag aacatgtatt tatttatgaa
    20821 ggaaaagaag agggggaata gggatgaatt attcacaaaa gtactttgta attatgggga
    20881 ttatttttct atttatgagt ggatttatga tattaacagg tataatgacg cattctgcac
    20941 cgccaagtcc tacttatacg ttacttgcaa tgatggttat gtgtttctac cttagttact
    21001 tacacccgca atttaaagaa aaagatgagc gaatgaaact cattcgttat aaaggaatgt
    21061 tcttcagttt ttttgcatta acggcatatt atcttctttt ctctatcggc ttaaacttaa
    21121 aaatacttac actatctgct actgaattat tgaatatact tatggcactt acgatgagta
    21181 ccgtctttat ctcatttgtt gttttggcaa aaagatatta agatggaaga gagaaaggaa
    21241 gattaacata tgcaaatgat gtatgctttt ggcattgggc ttgtattatt tttagcagta
    21301 ttcttattta ttcgtaaaga cgttcaaggc gggacgttaa cgaaacgagg attttataaa
    21361 atgatcggct gtttagttat tatgtttatt gcgattattg taatgattgt tttaataagt
    21421 cggtcactat agaatgtaaa aacggaacct tacttcggta aggttttttc tttattgttc
    21481 aacctaaaaa ttaccactaa atccatttac tataaatgac ttgtattata taatccaatg
    21541 aaatgataga taaggagtgt agtatatgaa taaaaaaact atcttctatt tattaacttg
    21601 tctactactt gtagctagta ctacttatat aatatgtaac aaacgagaac aagtgccacc
    21661 tatgttagta tgggacgaac aagaatacta tgttacgaat gaatctgcca aaatagaaga
    21721 agttgggcaa aaacttggcg aagtaacaaa gaaaattaaa acaagtaaaa aacctactaa
    21781 aaataaagaa tctaataaat tacaagagaa aacagaagta ttcacaatga ttgaggaaga
    21841 aaaagatcct caatcacctt taatcataaa ggaaacttat agtgatgaat atagggtagt
    21901 gaggccgatg ttgaagcagg tattgtgatg aaaaggagaa tcttttgtag acagtaattt
    21961 cgtatccgtg ggtgttaaga aaaacttttt tcctttgttt tattttgtcc ccctatcggt
    22021 gccgcttgca ttttgatgaa tagaggagca atacaaaaga gagatttcat tttatattta
    22081 ttatttgctg ctatgaatat atcactttgg ttattgctta tgatttttga ttggagtatg
    22141 tggatggtag tagggcatta tttgtttgga gcagttgtta ttgttttttc gaatatgaat
    22201 aagagctaag ccagcaacct taaagttgct ggtttttatt ttgctattta taatgaagaa
    22261 acaaataaat caatatgtaa agaaggaatg gtatagataa aagtaacgcc tgaacggtta
    22321 gaacagactg caaagacagt aaataacatc aggcacttct tagaatactt acataatgac
    22381 ttatacaatc aaattaagaa tatcgctata caatggaatg gagcgagtag agaacaattt
    22441 taacagagat ttaacgaagt aaaaccaaaa atgtttaatg ttttaataga agtaaaaaac
    22501 tacaatgttt attaatgaaa tctagtggta gactttcatt aataaacatt gtagtaaaac
    22561 agttggaaga tagattgaaa tatttgcccg aaggttcaca tcagactgtc gtgatagatg
    22621 tgagaggacc agatggaacg agagaaacat tgaagtaaat aagagaagaa ataaatcaaa
    22681 gaacatttgg acaggcagaa attatcatta aaaagataca aaaaagtagg ttatattaca
    22741 gagttagcac aaatgcataa gttataattt caagtgccat aaggataacc ctgaggagaa
    22801 aaaagacttc tgatttttaa gattatataa aatattcata gttgcaaaaa ctctattgtg
    22861 gtaaaatatt ctatataaat atttaaaagg ggaatggcta tgggggatat aaaagttact
    22921 cctgaacagt tgcgaaaagt ggcagggact attagatcaa ctatcacgaa tgcaactgca
    22981 acacaggagc gactaaaacg agatattgat atgatttcca gtaattggtt gggctcaacc
    23041 tatatgaaat ttaatacgga tttccgtgat tcatccttta agatggcaca atttataatc
    23101 atattggagc cacttgagaa gtttcttctt gattctgcta ataaatttga acaagtagat
    23161 aacatggatg ttgctattgc gttggcttcc agtattttaa ctgggaaacc ttttaaaggg
    23221 gattacgaaa ctttaacagg tgattttaaa ttagcagaag gaaatcgagt gggaatgaaa
    23281 gcagaaggtt cattgataaa aggtgaatat gagatttcga aaggaacaaa gcttactttt
    23341 aaagggggaa atggctcctt agagaccagt gttccaatgg atgaaaagac atttattagt
    23401 gatgttgcag gaggggggtt agtaggcttt aaagttggtg cttctctttt tgaggactca
    23461 atagaaaaag aaataaatag cggttttgca gaaaaagcaa cagttac
//
