LOCUS       NZ_CM002286            22330 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 plasmid
            pSros1 scaffold00002, whole genome shotgun sequence.
ACCESSION   NZ_CM002286
VERSION     NZ_CM002286.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 119017)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 119017)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 119017)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 16968
            Orig. end                         :: 39298
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002286.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22330
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="thioamitides"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..22330
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="single"
                     /product="thioamitides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22330
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12330](-)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12330)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
     gene            101..760
                     /locus_tag="M878_RS92805"
                     /old_locus_tag="M878_45790"
     CDS             101..760
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS92805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45790"
                     /product="hypothetical protein"
                     /protein_id="WP_158692943.1"
                     /transl_table=11
                     /translation="MSTPETTTPAGGADTLVGRCYTKARRHPLVIGRWPGGGVLWGGPY
                     SVPQLIVMVGSFVALILFRPVWAHFGVVLNVMFAFAVPYALGWTVRRLTVDGRNPLAAA
                     ASVLALLTAPSAGRLGGRPLKALNRARPVRGVCTVTWQEPAANRRSLVVGRAGDTRAFV
                     GELGAGKTRRAAPLAPQGAGSAAPEVGVARPRVLSGVGALIAARAAAGSGHEIEKG"
     gene            769..3354
                     /locus_tag="M878_RS91475"
                     /old_locus_tag="M878_45795"
     CDS             769..3354
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644109.1"
                     /locus_tag="M878_RS91475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45795"
                     /product="ATP-binding protein"
                     /protein_id="WP_023554011.1"
                     /transl_table=11
                     /translation="MQIPVRHLSGNVLWTVHGQTWAIWRVEGEGQAHVSRRAKMQRLAL
                     IESLVKSLHGEAMLLSLCPQVNPATVVERMISGIDIDASLAYEQVAHRTLDQLEQLELT
                     GRTDWLAVPLPTSRRQAVADAISAARCEVALQLGLLPAAVSVREELARLTQAADLAASW
                     PSQLRLRPATEAEILWMYGHATRRGLIEPMLPDPGQQQVRGRGRGAAALGQAVLVEGGH
                     RIAHDSDDEGGAAAGRGRRRRQSRTGQRAANPFAHRWLEVTTEFGPSYQALLALAEMPE
                     SFSFPGSEFLTSLDQFPFPVDWVVRLAVEDGASAEAKSRRQARELAGQYSEYDGEMAGV
                     PASVDKAAEGLAEYRDRLTSSKSEVEVRAMGAFAVWGGTPEEAERRATELQNYFAGGEY
                     TLARPRGEQENLWYGMLPGARTPRVMAQYAQFLIARDFAMSGPFSGSSLGDDTGPLYGL
                     QLAGGGIRPVHVDFTRGPRKKTSASAAFLGELGAGKSFAMKAAVYWILAGGRRQGIPGS
                     RGRAVIVDRTPQQEWVRFASACPGTTQVIHITRDASVSLDPLRLFAGKEAQRFTESFLT
                     LLLGISPMEDDGAALSEAIETVLAGPNPSMRVLAEELATRGAEDPASKSVARRLMAVKR
                     KDLARALFDESLPVVEADSADTVVFSVASLTLPKKRELEGDRLAKLEWEKTFGRAVMYL
                     IAALCRKIAFERREEFCTAVWDETWWLTSSPEGLELLIELLRDGRKHNAGALLGSHDPY
                     DFGISDPELGTIVRGLLPRRLLFRHTDAVLARRSLEFLGLDANDADLVTEVTTHLSPIN
                     VSDDEQAARAGECLHRDLLGRIGGMQVLIPNDPKVAAVIHSDPEAAVAA"
     gene            3351..>5295
                     /locus_tag="M878_RS91480"
                     /old_locus_tag="M878_45800"
     CDS             3351..>5295
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS91480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45800"
                     /product="hypothetical protein"
                     /protein_id="WP_158692944.1"
                     /transl_table=11
                     /translation="MTKTQTAAMPQTKARIGQVGTRAARWLSPGRTLAAGIALFLAATV
                     VSLVLAGTAGAVPTPSPSPSPSLYQPGLETPVPGLLHPPSPTAPSPTAPTPAASASAGT
                     GAADGGQDTSKETQAQKKAREEAEKKEKAKQVLDEWNKRVEQYKADRRNGGVLSAFEVT
                     DRDGNPVSSYRVYADTGGWSDWDLKIESFLVDGMFLETKYGVSFACFVLAWSLAFKMAG
                     LLLKPALTVSNALYANVIVQIGLPGLCLTYAGTVAAWHLMFGRRARGWGEAAASLVISA
                     LAITTLAAPPQMMLSEQHGAVGSARSLAVDVAALILDNQEAIHTPKTTTNNGIDDSVPA
                     GTSAGAQVRSKASALARPITDELVDAFVVRPSELLSYGQTFDGKCAKQFRDSRIQQAVA
                     DQWLDDALNAGPNAMRKHIPWIGDTLGSVMKGATFGPNELVKEKVKAVGPIAKFEKACV
                     KGDVTSLKKASMDKVGGAFFVMLASLLVCLFIIVVDWMFLYAQICIAKEAMIAKCALAI
                     GVLPGPGRFWLWNRAVTVLRYLGLMVLAVASLAVLIVVVKAILNAPESDLPGGVTIRFV
                     VLDIVTISAFRYRRQLVRSTEGLALRARTRLGNSVFGGSAPVDPGPPPRRHSLGRRLLA
                     GGVMLGALAASGG"
     assembly_gap    5296..6043
                     /estimated_length=748
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            6215..7333
                     /locus_tag="M878_RS91485"
                     /old_locus_tag="M878_45805"
     CDS             6215..7333
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013073.4"
                     /locus_tag="M878_RS91485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45805"
                     /product="bifunctional lytic transglycosylase/C40 family
                     peptidase"
                     /protein_id="WP_023554013.1"
                     /transl_table=11
                     /translation="MTSTTKKTLLASGTVLAPLAVVLGICILFVAAVAGGAAEHQDEGG
                     DGTALTGQGMPAKVDGVDAVMLAAYGRAAQQVTTLRPKCTGMRWSVVAGIGEVESTHAA
                     GHTIAAGGDITPPIIGPRLDGSGTGGNTTPVRDTDHGRYDGDTQYDRAVGPMQFLPSTW
                     ESIGQDGNNDGIKNPNNAFDAALTTAVYLCGTGPSDLSNDAQLRQAILRYNHSGQYADK
                     VIGYIHQYDTLAPNVTTGTTDVSGNAGAVIAAALKEQGIPYVWGGGDINGPTGGGFDCS
                     GLMVYAFYQGAHITLPRTSQEMRTVGTSVSRDQMQPGDLIVFNNDGNWGHVGLYLGGGQ
                     MVNAPRPGKNVETTVVSTGYWTRYDWDVRRVL"
     gene            complement(8147..9160)
                     /locus_tag="M878_RS91490"
                     /old_locus_tag="M878_45810"
     CDS             complement(8147..9160)
                     /EC_number="1.1.1.94"
                     /GO_component="GO:0009331 - glycerol-3-phosphate
                     dehydrogenase complex [Evidence IEA]"
                     /GO_function="GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0046167 - glycerol-3-phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130478.1"
                     /locus_tag="M878_RS91490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45810"
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="WP_023554014.1"
                     /transl_table=11
                     /translation="MSRVAVYGAGSWGTAFSLVLADADCEVTLWGRRPALVEAINETRS
                     NPDYLPDVTLPANVKATSDPAEAARGADIAVLAVSAQSARPLLDAWQALWEPRTVFVSL
                     MKGIELGTGKTMSEVIAETTSARPERIAVVSGPNLAGEIVARKPAASVAACTDEDTAAL
                     VQAACRTPYFRPYTNTDVIGCELGGAIKNVIALAVGLTDGMGLGDNAKAGLMTRGLAEA
                     TRLGAAMGADPLTLAGLAGMGDLIATCSSTLSRNHTFGAHLGRGLSVQEAKTQTRQTAE
                     GVASCKAIYDLGRRHHIEMPITETVVDIIHNGQSPQSAVRTLMSRAVKPEARTASR"
     gene            complement(9223..10008)
                     /locus_tag="M878_RS91495"
                     /old_locus_tag="M878_45815"
     CDS             complement(9223..10008)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568345.1"
                     /locus_tag="M878_RS91495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45815"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_023554015.1"
                     /transl_table=11
                     /translation="MDSPHFTEREQRLAAVYDKLHEARGTATIVSDLYAQAMGDTYPYE
                     VEAAGAVDWPLLGTMVGTLRLAPGHQLVDLGCGTGGVGLWLARALAVHLTGVDISATAV
                     RRATGRVPEFLPAGRARFLVGSLRATGLPDRHAHGLVCVDALGFEPDRTAVLKEIHRVL
                     RPGGRAVVTSARRRTNPVLPPWPEQAVAAGLACEGEQERLHEPQLWQRLYRLWIEHETD
                     LRKQLGDEQAESMLLEARTRGLMLDDRCALAVTLRRPKE"
     gene            complement(10001..11149)
                     /locus_tag="M878_RS91500"
                     /old_locus_tag="M878_45820"
     CDS             complement(10001..11149)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568344.1"
                     /locus_tag="M878_RS91500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45820"
                     /product="YcaO-like family protein"
                     /protein_id="WP_023554016.1"
                     /sec_met_domain="YcaO (E-value: 8e-60, bitscore: 196.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSITLTGTVRTRTSEETWEALKPHIARLGISRVARLTGLDYLGI
                     PVWTAVRPNAHTLVTSQGKGATDTLAKISAVLESAELFHAEQPLKADIRATHRDLDLPY
                     PMHALPVKIDHPALADVALDWVTGHSLLSAEPVLVPADVVRRKTHPSAAEPEVFHVTSN
                     GLACGNTLPEATLHALLETIERDVLHHDYVSGSQLRTLVDPVTVTDPYCRSLVDRFTSA
                     GMWLEIAFVDNRYGVPVCAAYIWSEDYPITFAGSGCHFDPQIALSRALTEAAQSRLTCI
                     AGTRDDLDVHENAFAADPERPAPADIPVGDWSSLTHQFQPEDDDLGQHLQAITARVAST
                     TGYEPIAFPLHDSPAYAAVKVVSPGLEMRIIRSIPRAGSRRG"
     gene            complement(11146..12330)
                     /locus_tag="M878_RS91505"
                     /old_locus_tag="M878_45825"
     CDS             complement(11146..12330)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568343.1"
                     /locus_tag="M878_RS91505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45825"
                     /product="TfuA-like protein"
                     /protein_id="WP_023554017.1"
                     /sec_met_domain="TfuA (E-value: 6.3e-41, bitscore: 132.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHVFTGPTLSPDEPALKAPDLRLRPPIRHGDLFDPQITVGDTVV
                     IIDGVYHHSPAVRHKEIIWTLGRGIRVIGAASIGALRAAELSDCGMIGIGSVWHDYNTG
                     LLDGDDEVAVAQLAGGDPRACTWPLVRVRQVLSHALRKNVVDAAQADRLLGTLADVYYA
                     HRSLDAVMRVSRRENLPEFADWLTHELATDEHFGDVKRQDALDALDLAREMAKTPAEPV
                     EGLTWTTRCFRQWANAFAALDTEHGRLRTLERVTFQQIFDPRFKQVWWEYLISLGTSDL
                     PWTVACAVINPRVDLSDEQTAARLLIRETPTDRTDVARYSAVNDQAREANRGFFPEAIK
                     ESVVRDMLAAVWGTGPDGLEEEAWVRGLHGVREAVDAARPFVLGFLKDQEAARR"
     misc_feature    complement(12265..12267)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12408..12539)
                     /locus_tag="M878_RS000000101275"
                     /old_locus_tag="M878_45830"
     CDS             complement(12408..12539)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS000000101275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45830"
                     /product="hypothetical protein"
                     /protein_id="WP_023554018.1"
                     /transl_table=11
                     /translation="MSKAQEAAQSTAVVADGTDVEELVDTSAVVRSEDVEQDECYTF"
     gene            complement(12896..13069)
                     /locus_tag="M878_RS98145"
                     /old_locus_tag="M878_45835"
     CDS             complement(12896..13069)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS98145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45835"
                     /product="hypothetical protein"
                     /protein_id="WP_023554019.1"
                     /transl_table=11
                     /translation="MSIVLTGLGILAHADGRTGREAWRIMRRRHPRLTWAVTTAYALVV
                     GLAVTVVARLVT"
     gene            complement(13329..13913)
                     /locus_tag="M878_RS91510"
                     /old_locus_tag="M878_45840"
     CDS             complement(13329..13913)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS91510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45840"
                     /product="hypothetical protein"
                     /protein_id="WP_023554020.1"
                     /transl_table=11
                     /translation="MSTHTVMAAPSLPRPRSAPAQELTAAAVGPVPYNWLEPTGRRDQV
                     LTAWGRRQLAEVPVGLSFDTILVPGALARDVLDRVRAAGIHPGPVILGPSGAEVIIRLD
                     SAPGWCAPNSLLLRRGALLLLPPPTVHVPKMMAARSWLIPPAQREASVPPGDGLPSGDD
                     LLRPYLAAVQAAAAAVRLADPGSPSADRMDR"
     gene            complement(13910..14608)
                     /locus_tag="M878_RS91515"
                     /old_locus_tag="M878_45845"
     CDS             complement(13910..14608)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="M878_RS91515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45845"
                     /product="ATP-binding protein"
                     /protein_id="WP_245238462.1"
                     /transl_table=11
                     /translation="MRTAHADDLDSSLMHPQTPRAASSARTAKGRSVSDTMLRNRHRRA
                     VRVLEADDGTPVVTDVLPREPGSVPKARQLVREALVAWELTHLTDAAELIISELSANAV
                     QHTRYPVFRVKVQRCHDGRVRLAVIDKSTAEPVLRPMDDEAEEGRGLALVAAVAHEWGI
                     DPLGWGKRVWADLEVPEPSEQHHRQWQPDEVRMWHTHRAQALYLLVLLAVMGALVILIM
                     HGHQTEGGIR"
     gene            complement(14730..14852)
                     /locus_tag="M878_RS000000101280"
                     /old_locus_tag="M878_45850"
     CDS             complement(14730..14852)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS000000101280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45850"
                     /product="hypothetical protein"
                     /protein_id="WP_023554022.1"
                     /transl_table=11
                     /translation="MTSPKPPLRTRITEAVITIALVSLVVLAFGIALVHTLQSH"
     gene            complement(14849..15385)
                     /locus_tag="M878_RS91520"
                     /old_locus_tag="M878_45855"
     CDS             complement(14849..15385)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS91520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45855"
                     /product="recombinase family protein"
                     /protein_id="WP_158692945.1"
                     /transl_table=11
                     /translation="MRLQPVPADELDESWLRWRPVEPRFRPTPGGRLTALRRSVFENAL
                     AAIKPGRPIKVTTYVFADLGVDTDGTHALLAEHARERGWSVDRERFTDEPTGGSASTRP
                     QFNLAVRRAGSGFVDGVLALGRDSMPSTDEAYEAYLHWLHRHYAFIAFLQPTTGRTQWR
                     QNAGNVTSDHGGRRS"
     misc_feature    complement(15278..15280)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15513..16394)
                     /locus_tag="M878_RS91525"
                     /old_locus_tag="M878_45865"
     CDS             complement(15513..16394)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS91525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45865"
                     /product="ATP-binding protein"
                     /protein_id="WP_158692946.1"
                     /transl_table=11
                     /translation="MTGQPTSGLQTDAPAVVWGDLPVPPLGDTASDSASVVLYTCAFDS
                     QIANRALAVLHDFAARRGWNVVHDLYDLAALDTPRQRRTGWRTVEHELTSGAATGVVAP
                     AEQEIAWYPGDRIALRVWLLGIPAFAVYPQAGSCLRTPDVAGAVALPSGAGAPVDRQLS
                     RSYRLNLAGLRQVRTDAITRLTVLGWPGNIMAAVRVLAILTANAVVHANTDSGTDARMT
                     VVLAVTEDDELRIDVQDPSPEFRDSAAALNGEKGRGLREARLLGAEVTWSLAEDGRTKT
                     VRARMVPGEVPA"
     misc_feature    complement(16038..16040)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16493..16503)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            16697..17557
                     /locus_tag="M878_RS91530"
                     /old_locus_tag="M878_45870"
     CDS             16697..17557
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="M878_RS91530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45870"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_023554026.1"
                     /transl_table=11
                     /translation="MSDPNGPTVRRRRLGSELRRLRERAGLDQLAAANHLECSTSKISR
                     LERGQGLAKQMEMRSLLDLYRVTDEDERTAILTLHKTAAEVGWWEQAEYEEVLPSGLGV
                     YVGLEYDARALQCWELGFVPGLLQTADYARAVVSSLPRLSTDEVDRLVKARMQRQTRLT
                     QEKDPLELWAVIDESVLHRPLGGADVMRAQLDALAEWTARTNVTLQVYRPKDVHPGLRG
                     SFSLLEFGPADPRIGYVDSPGGNAFLEKDKQVRVLADTFDRLRAGALDPEESAALVRSL
                     AAEEK"
     gene            17560..17775
                     /locus_tag="M878_RS91535"
                     /old_locus_tag="M878_45875"
     CDS             17560..17775
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470038.1"
                     /locus_tag="M878_RS91535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45875"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_031227475.1"
                     /transl_table=11
                     /translation="MNHPAQTALGADTLAWWKSSYSSEQGACVEVAHAPQGRMAVRDSK
                     VHAGPHLLVDTHAFTALVAGLVTGTV"
     misc_feature    17891..17906
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.27"
                     /tool="antismash"
     misc_feature    complement(18042..18051)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            18070..18558
                     /locus_tag="M878_RS50665"
                     /old_locus_tag="M878_45880"
     CDS             18070..18558
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS50665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45880"
                     /product="hypothetical protein"
                     /protein_id="WP_023554028.1"
                     /transl_table=11
                     /translation="MVGDVVPQAPGVVHGFVLVLGAVVEHVGWLAGAAGAVLIIWAASA
                     AWWRRRAVRELERRARFELVPAVTFDPQMGDIGQAAARLDGARAAAGGVPKRAGAVRIR
                     VWAGPESQLHYGWEGPERAASVLRMPGYRQVEVRPVDAARSASTQVRFEGVSPQAGGW"
     gene            18555..20822
                     /locus_tag="M878_RS91540"
                     /old_locus_tag="M878_45885"
     CDS             18555..20822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011039453.1"
                     /locus_tag="M878_RS91540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45885"
                     /product="hypothetical protein"
                     /protein_id="WP_023554029.1"
                     /transl_table=11
                     /translation="MSAVVLSKQGQAAVPEATPVPGVSRGLYVARAELVLARADHWPLG
                     KPVLDPDPLEQVAAAFAEVRTEDGEEAELIVDLLPVPGPAVARRRRRLLARASRRGPTA
                     FGEELTVGGSGGSVLSQVWDVLNGPSGKRTSGGAGARLPRQSDLSDGIGKFAPGAQVFA
                     LQVLVRCTARHPARARARLHQVMAALQALRGQNALVPVGPRLGGWRPYSDVWWRRRAFD
                     RRFARGDFAPARRRQWVTWQEVAALLKPPSRHCTAQNITRTGGVVSPAPAGLPTWTGQK
                     DVLPLGYVTGADGRRRLGGAYAKDVLFGSSLGKSGFGKTELALVQFAARAYAEDGALLF
                     DPHRTAWLRIKPYLAHPVLADRIWEVDLSRARDEDLMSCWNPLSMEGRRLDEVQEIVGA
                     VVGAISSAHSWGERATRARTILSNAVRTLAELSHLLIQDGHPELQPTVFQISTLLEDED
                     WRKAVLAHLPQATGRYWTRSFANVEPNAMNTVTNVLYRFSSSRSLRAFLGSPRSGYDLR
                     RAMATSAVVGLCPSGTGESDELICALLLFDLFREGMARASLPADQLHTMWSWVDELTSV
                     DGASHGYIAKILEQLRKYELRFVGMTQMVMRLSDTTRQALMQNQSWLSATGADADEAAF
                     VAKRMPGIDPATIQQIDRYCYIQSVQLHGKRTAPFRVEGVAVDDVFADYYNPDGLEALD
                     KAIDANVQRRPVGDILAGLDRLDDAILAHLTRRPSGGTPRPAGSGDVVHRLPRPTHPTQ
                     KG"
     gene            20828..21778
                     /locus_tag="M878_RS91545"
                     /old_locus_tag="M878_45890"
     CDS             20828..21778
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522953.1"
                     /locus_tag="M878_RS91545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_45890"
                     /product="replication-relaxation family protein"
                     /protein_id="WP_023554030.1"
                     /transl_table=11
                     /translation="MSAPALTRPRALSRLAQELLPVLYQHRLLTAEQLTRLLRPTATTS
                     RYVRKQLLQLQVHDLADATCRRHSRAGELLWYITPLGAATVEAGRELPARPYQMTSQAA
                     ASAVQEHTLAINDTALAFVAHARRLGDGCGPLSWDMEVAHRVRDGNTRSGDEAWLTPDA
                     VLHYTHTTRGGERMLLDFFLEVDRATMPVARLAAKLHAYARYATYIPQPAPGARHSTAG
                     GLVQEAWRERYRAFPRLLLVLTGAPTHTLATRALDLRALAAADPRLQRAAAQLRAGVTS
                     LELLTRHGPFADIVTPLLGPDTPTTVLLPAPAVSA"
     gene            21775..22206
                     /locus_tag="M878_RS50670"
                     /old_locus_tag="M878_45895"
     CDS             21775..22206
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS50670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_45895"
                     /product="hypothetical protein"
                     /protein_id="WP_158692947.1"
                     /transl_table=11
                     /translation="MSASVSSAPFVPAPTAKGFSMLLGKLRRRRQAAATRTLERPYATP
                     HACSAVVDGLPQLDSPLVTELIALQAHTRHLGWLSAREQCPEEYRHLARLVLQHVLEGW
                     HAQTGGRGRLEDLLVFPDPAGPVPGHCQHERDHMTTYGS"
ORIGIN
        1 tgacgctcct gcgtgaccag accggtgaga cctggaacca caacggcacc aaggcggccg
       61 ctctggtcac cgcccctgtc gccaccggtg gtgaaggccg gtgagcacgc ccgagacgac
      121 aacgcctgcg ggtggtgcgg acaccctggt gggccgctgc tacaccaagg cgcgccgcca
      181 cccgctggtg atcgggcggt ggccgggcgg tggcgtgctg tggggcgggc cttactccgt
      241 gccgcaactg atcgtcatgg tgggctcgtt cgtcgctctg atcctcttca ggcccgtctg
      301 ggcgcacttc ggggtcgtgc tgaacgtgat gttcgccttc gcggtgccct acgccctggg
      361 gtggacggta cgccggctga ccgtggacgg ccgcaatccg ctcgcggccg ccgcaagcgt
      421 tctggcactg ctgaccgcac cttccgccgg ccggctcggc ggacgaccgc tgaaggcgct
      481 gaaccgggcc cgcccggtgc gcggcgtgtg caccgtcacc tggcaggagc ctgctgccaa
      541 ccgccggtcc ctcgtcgtcg gccgggcggg cgacacgagg gcgttcgtgg gcgagctagg
      601 ggccggaaag acccggcgtg ctgcgcccct ggcgcctcag ggggccggga gcgcggcgcc
      661 ggaggtgggg gtggcgcggc cgcgggtgct gtccggggtg ggcgcgctca tcgcggcgcg
      721 ggccgcagcc ggcagtggac acgagatcga gaagggctga gttcagcgat gcagattccg
      781 gtgcggcacc tgagcgggaa cgtgctgtgg accgtccacg gccagacctg ggccatctgg
      841 cgggtcgagg gcgagggcca ggcgcacgtg tcgcgccggg cgaagatgca gcggctcgcc
      901 ctcatcgagt cgctggtgaa gtcgttgcac ggggaggcga tgctgctgag cctgtgcccg
      961 caggtcaacc cggccaccgt agtggaacgg atgatctccg ggatcgacat cgacgcttcg
     1021 ctggcgtacg agcaggtggc gcaccgcacg ctggaccagc tcgagcagct ggagctgacc
     1081 gggcggaccg actggctggc tgttccgctg cccacctcgc ggcgccaggc cgtcgccgat
     1141 gcgatcagcg cggcacggtg tgaagtcgcc ctgcagctgg gcctgctgcc tgcggcggtc
     1201 tcggtgcgcg aggaacttgc gcggctgacc caggcggcgg acctggcggc gtcgtggccg
     1261 tcgcagctgc ggctgcggcc ggccaccgag gcggagatcc tgtggatgta cgggcacgcc
     1321 acgcgccgcg ggctgatcga accgatgctg ccggaccccg gccagcagca ggtgcgcggc
     1381 cgtggccgcg gtgcggccgc gctcggccag gcggtgcttg tcgagggtgg ccaccgcatc
     1441 gcccacgaca gcgatgacga aggcggcgct gcggcggggc gggggcgccg caggcggcag
     1501 tctcgtacgg ggcagcgggc ggcgaacccg ttcgcccacc ggtggctgga ggtgaccacc
     1561 gagttcggtc cctcgtatca ggcactgctg gcgctcgcgg agatgcccga gtcgttctcc
     1621 ttcccgggca gtgagttcct caccagcctc gaccagttcc ccttccctgt ggactgggtg
     1681 gtgcgcctgg ccgtcgagga cggtgccagt gcagaggcca agtcgcgccg ccaggcccgc
     1741 gaactggccg gccagtacag cgagtacgac ggcgagatgg ccggcgtgcc cgccagtgtg
     1801 gacaaggccg ccgagggtct ggccgagtac cgcgaccggc tgacctcctc caagagcgag
     1861 gtggaggtga gggccatggg cgcgttcgcg gtctggggcg gcacgccgga ggaggccgaa
     1921 cgcagggcga cggagctgca gaactacttc gccggcggcg agtacaccct cgcccgtccg
     1981 cgcggcgagc aggagaacct ctggtacggg atgctgcccg gtgcccgcac cccgcgagtg
     2041 atggcccagt acgcccagtt cctcatcgcc cgcgacttcg ccatgtccgg gccgttctca
     2101 ggcagctcgc tcggcgacga caccggcccg ctgtacgggc tgcagctggc cggcggcggg
     2161 atccgcccgg tccacgtcga tttcacccgc ggcccccgca agaagacctc ggcctccgcc
     2221 gccttcctcg gcgagctggg agccggcaag agcttcgcga tgaaggcggc cgtctactgg
     2281 atcctggccg gcggccggcg ccagggcatc ccgggcagcc ggggccgcgc ggtgatcgtg
     2341 gaccgcacac cgcagcagga atgggtgcgc ttcgcctccg cctgcccggg caccacccag
     2401 gtcatccaca tcacccggga cgcgtccgtg tccctggatc ccttgcggct gttcgcgggc
     2461 aaggaggccc agcggttcac cgagtcgttt ctgacgctgc tgctgggcat ctcaccgatg
     2521 gaggacgatg gcgccgcgct cagcgaggcg atcgagaccg tcctggccgg cccgaacccc
     2581 tcgatgcgcg tgctcgccga ggaactcgct acacgggggg cggaggaccc ggcatccaag
     2641 tcggtcgccc gccggctgat ggcggtcaag cgcaaagacc tggcacgcgc cctgttcgac
     2701 gagtcgctgc ccgtcgtcga agccgactcg gccgacaccg tcgtcttctc cgtcgcctcg
     2761 ctcacgctgc ccaagaagcg ggaactggaa ggcgaccggc tggccaagct ggagtgggag
     2821 aagaccttcg gccgcgccgt gatgtacctg atcgccgccc tgtgcaggaa gatcgccttc
     2881 gagcggcggg aagagttctg caccgcggtg tgggacgaga cctggtggct gacctcctcg
     2941 cccgagggcc tggagctgtt gatcgagctg ctgcgcgacg ggcgcaagca caacgccggc
     3001 gcgctgctgg gctcgcatga cccgtacgac ttcgggatca gcgacccaga actcggcacg
     3061 atcgtgcgcg gcctgctccc caggcggctg ctcttccgtc acaccgatgc ggtcctggcc
     3121 cgccggagcc tggagttcct cggcctggat gcgaacgatg ccgacctggt caccgaggtc
     3181 accacccacc tgtccccgat caacgtctcc gacgacgaac aggccgcgcg cgccggggag
     3241 tgcctgcacc gcgacctgct gggccggatc ggcggcatgc aggtcctcat ccccaacgat
     3301 ccgaaggtgg cggccgtcat ccactccgac cccgaggcgg cggtggcggc atgaccaaga
     3361 cccaaacggc cgccatgccg cagacgaagg cgcgcatagg gcaggtgggc acgcgagcgg
     3421 cccgctggct gtcgcccggt cggacactcg ccgccgggat cgccctgttt ctcgccgcca
     3481 cggtggtctc gctcgtgctg gccggcaccg caggcgccgt acccaccccc tcaccgtcgc
     3541 cctcgccgtc cctgtaccag ccgggcctgg agactcccgt ccccggactg ctgcatcctc
     3601 cgtcccccac cgccccgtcc cccaccgccc cgacccccgc cgcctctgcc agcgccggga
     3661 cgggtgcggc cgacggtggc caggacacca gcaaagagac acaagcgcag aagaaggcgc
     3721 gtgaggaggc ggagaagaag gagaaggcca agcaggtcct cgacgagtgg aacaagcggg
     3781 tcgagcaata caaggccgac cggcgcaatg gcggtgtgct gtccgcgttc gaggtcaccg
     3841 accgcgacgg taacccggtc tcctcctacc gcgtctacgc cgacaccggc ggctggtcag
     3901 actgggatct caagatcgag agcttcctcg tcgacgggat gttcctggaa accaagtacg
     3961 gggtgagctt cgcgtgcttc gtgctcgcct ggtcgctggc gttcaagatg gccggacttc
     4021 tcctcaagcc ggcgctgacg gtctccaacg ccctgtatgc caacgtcatc gtgcagatcg
     4081 ggctgcccgg gctgtgcctg acctacgccg gcaccgtggc cgcctggcat ctgatgttcg
     4141 ggcgccgggc acgcggatgg ggcgaggccg ccgcctccct ggtcatctcc gcgctcgcca
     4201 tcaccacgct cgccgcgccg ccgcagatga tgctgtccga acagcatggc gccgtcggca
     4261 gcgcccgcag cctggccgtc gacgtggccg ccctgatcct cgacaaccaa gaagccatcc
     4321 acacacccaa gaccaccacc aacaacggca tcgacgactc cgtcccagcc ggtaccagcg
     4381 ccggcgcaca ggtccggtcg aaggcctccg cgctggcccg cccgatcact gacgaactcg
     4441 tcgacgcctt cgtcgtcagg ccttccgagc tgctgtcgta cgggcagacc ttcgatggca
     4501 agtgcgccaa acagttccgt gactcccgca tccagcaggc cgtggccgat cagtggctcg
     4561 acgacgccct gaacgcgggc ccgaacgcca tgcgcaagca catcccgtgg atcggcgaca
     4621 ccctcggcag cgtcatgaag ggggccacat tcggccccaa cgagctggtc aaggagaagg
     4681 tcaaagccgt cggcccgatc gcgaagttcg aaaaggcctg cgtcaagggc gatgtgacat
     4741 cgctgaagaa ggcctccatg gacaaggtcg gcggtgcctt cttcgtgatg ctcgcctccc
     4801 tgctggtctg cctattcatc atcgtcgtcg actggatgtt cctctacgcg cagatctgca
     4861 tcgccaagga agcgatgatc gccaagtgcg cgctggccat cggcgtcctg cccggtcccg
     4921 gacggttctg gctgtggaac cgggccgtca ccgtcctgcg ctacctcgga ctgatggtcc
     4981 tcgcggtcgc ctcgctcgcc gtcctcatcg tcgtcgtcaa ggcgatcctc aacgcacccg
     5041 agagcgacct gcccggcggc gtgaccatcc ggttcgtcgt gctcgacatc gtgacgatct
     5101 ccgcgttcag gtaccgcaga cagctcgtcc gcagcacaga gggtctcgcc ctgcgcgccc
     5161 ggacccgcct gggcaacagc gtcttcggcg gcagcgcccc cgtcgatccg ggcccgccac
     5221 cccggcgaca cagtctcggg cgccggctgc tggccggcgg cgtcatgctt ggcgcgctcg
     5281 ccgccagcgg cggcgnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngcctgcc ccggcccggc
     6061 gccgtccggt tccgccacgc gtaccgcagc cggccgccag cccggcccag gcggcgctgc
     6121 agatgcggct gcaccgcatc cgcaaccgcg cagccacccc gcccgcggtg cctggtccgc
     6181 gtcccgcgcc ccgccgtcga ggcggtcgcc gcccgtgacc tccacgacaa agaagaccct
     6241 gctcgcctcc ggcacagtgc tcgcgcccct cgccgtcgtc ctgggcatct gcatcctgtt
     6301 cgtcgccgcc gtggccggcg gagccgccga acaccaggac gaaggtggcg acggtacggc
     6361 tctgaccggc caagggatgc ccgccaaggt ggacggggtg gacgcggtca tgctcgccgc
     6421 ctacggccgc gccgcccagc aggtcaccac actgcgcccg aagtgcacag ggatgcgctg
     6481 gtcggtggtc gccggaatcg gcgaggtcga atccacccac gccgccggcc acacgatcgc
     6541 cgcaggcggc gacatcacac cgcccatcat cgggccccgg ctcgacggca gcggcaccgg
     6601 cggcaacacc acccccgtcc gcgacaccga ccacggccgc tacgacggcg acacccaata
     6661 cgaccgcgcg gtcggcccca tgcagttcct gccctccacc tgggaaagca tcggccaaga
     6721 cggcaacaac gacggcatca agaaccccaa caacgccttc gacgccgccc tgaccaccgc
     6781 cgtgtacctg tgcggcaccg gccccagcga cctgagcaac gacgcccaac tacgccaggc
     6841 gatcctgcgc tacaaccact ccggccagta cgcggacaag gtcatcggct acatccacca
     6901 gtacgacacg ctcgccccca acgtcaccac cggcaccacc gacgtcagcg ggaacgccgg
     6961 tgccgtcatc gcggccgcgc tcaaggaaca gggcatccca tacgtgtggg gcggcggcga
     7021 catcaacggc cccacaggcg gcggcttcga ctgctccggc ctgatggtct acgccttcta
     7081 ccaaggcgcc cacatcaccc tgccccgcac ctcccaggag atgcgcaccg tcggaaccag
     7141 cgtctcccgc gaccagatgc agcccggcga cctgatcgtc ttcaacaacg acggcaactg
     7201 gggacacgtc ggcctctacc taggaggcgg ccagatggtc aacgcacccc gcccgggcaa
     7261 aaatgtagag accaccgtcg tctcaacggg ctactggacc cgatacgact gggacgtcag
     7321 gcgcgtcctg taacggcagg ttccgacttc acgtgtcatc gtccggccgg tctgtcatcg
     7381 gtctgccgcc ggcaggcggg gcatcctcac cgacaggatc caagagccct ggccgtgctc
     7441 accgactccg cagcactgtt gcagacagtg acttttcgtg atgtcgccga ggcgtcgacg
     7501 ggcgctggcc gacgcgtcac gcaccggcca cgcacacgcg cgtctttggt cagttggccg
     7561 atcggccacg gcgacggcca gtggccgcta cgcatgaccg gccctcggtc ccggccatcc
     7621 ggccaccggc ggccgcacac ggctgtggcc ggtcacggcc ggcgcttgtc cggccatggc
     7681 cggtggccgc cacgactgga agcggtcacc gccccatggc cgccccgatt ggcagccgtc
     7741 ccttcccggg caacgccgac gcgatttcat actgcgcacc acacggatac ccatgccatg
     7801 acctgcgggt atccacagct tgcggagtgg gtatccaggc ggggcaaggg gttgggtatc
     7861 cgtaccgcgc tgccattccg atgacttgac actcatcagc ccgaacagcg gccaccggcg
     7921 ccagcgggcg actggccacg acttggtcac cggtcacgga tgcgtggccg aggactggtg
     7981 accaagatcg tgggtggtaa ggcagcggat gaaggcgtgg gccgtggccg ttgggcatgc
     8041 acgacggacc ggtcaatcga ggcccttcgg gacccggagt acgcgctgcc cggtccgcac
     8101 gaccttgcct ctgactgtcg gccatggtca ctctgcgttg ttgccctcag cgactagctg
     8161 tgcgggcctc tggcttgacc gcgcgagaca taagggtgcg gactgcgctc tgcgggcttt
     8221 ggccgttgtg gatgatgtcg acgacggttt cggtgatcgg catctcgatg tggtggcgtc
     8281 gcccgaggtc gtagatcgcc ttgcaggagg cgactccttc ggcggtctgc ctggtctgcg
     8341 ttttggcctc ttggacgctc aggccacggc cgaggtgggc gccgaaggtg tggttcctcg
     8401 acagtgtcga cgagcaggtg gcgatcagat ctcccatccc ggcaaggccg gcgagggtaa
     8461 gcgggtcagc acccatcgcg gcgccgagcc gggtcgcctc ggcgagtccg cgagtcatca
     8521 gccctgcttt ggcgttgtcg ccgagtccca tgccgtcggt gaggccgacg gccagggcga
     8581 tgacgttctt gatggcgccg ccgagttcgc agccgatcac gtcggtgttc gtgtacggcc
     8641 ggaagtacgg cgtgcggcag gcggcctgga cgagcgcggc cgtgtcctcg tcggtgcagg
     8701 cggcgacact cgcggccggt ttccgggcga cgatctctcc ggccaggttc ggtccggaca
     8761 ccacggcgat ccgctctggc ctcgcgctcg tcgtctcggc gatgacctcg ctcatcgtct
     8821 tgccggtgcc cagctcgatg cccttcatca gcgacacgaa caccgtgcgc ggctcccaga
     8881 gcgcctgcca agcgtccagg agcgggcggg cgctctgggc ggagaccgca agaacggcga
     8941 tgtcggcgcc gcgcgcagct tcggccgggt cggacgtggc cttcacgttc gctggcagcg
     9001 tcacgtccgg caggtagtca ggattgctgc gggtctcgtt gatcgcctcg accagggccg
     9061 ggcggcggcc ccacagcgtg acctcgcagt cggcgtcggc gaggacgagg gagaacgcgg
     9121 tcccccagga gccggctccg tagacagcga cacgggacat gcggtgaatc tccttgcaga
     9181 tcagcccgta tcgggggcag cgcgccctgg tcacggggat gttcactcct tggggcgcct
     9241 caatgtaacg gcgagcgcac agcggtcatc gagcatcaag ccacgtgtcc gcgcctccaa
     9301 gagcatgctc tcggcctgct cgtcaccgag ctgcttgcgc aggtcggtct cgtgctcgat
     9361 ccagagccgg tagaggcgct gccacagctg cggctcgtgg aggcgttcct gctccccttc
     9421 gcaggccaga ccggcggcta ccgcttgctc gggccacggc ggcaggaccg ggttcgtgcg
     9481 ccggcgggcg gaggtgacga cggcgcggcc gccgggccgc aggacgcggt ggatctcctt
     9541 caggacagcc gtccggtcgg gttcgaagcc cagtgcgtcc acgcacacca ggccgtgggc
     9601 gtggcggtcg ggcagcccgg tcgcacgtag cgagcccacc aggaacctgg cgcgtccggc
     9661 cgggaggaac tcgggcacgc ggccggtggc ccgacgcacg gccgtggcgg agatgtcgac
     9721 gccggtcagg tgcacggcga gcgcgcgggc cagccacagg ccgacaccgc cggtgccgca
     9781 gccgagatcc acaagctgat gcccgggcgc cagacgcagc gttcccacca tcgtgccgag
     9841 gagaggccag tcgactgcgc cggccgcctc gacctcgtac gggtaggtat cgcccatggc
     9901 ctgtgcgtac aggtcgctga cgatggtggc ggttccacgg gcctcgtgca gtttgtcgta
     9961 cacggcggcg agccgctgtt cccgttcggt gaagtggggg ctatccacgg cggctccccg
    10021 cgcgggggat ggaccggatg atgcgcatct ccaggccggg gctgacgacc ttgacggccg
    10081 cgtacgccgg cgagtcgtgc agggggaagg cgatcggctc gtacccggtg gtggaggcga
    10141 ctcgggctgt gatggcctgg aggtgctgtc cgaggtcatc gtcttccggc tggaactggt
    10201 gcgtcaggct gctccagtcg ccgaccggga tgtccgccgg tgcgggccgt tcggggtcgg
    10261 cggcgaaggc gttctcgtgg acgtcgagat cgtcccgggt accggcgatg cacgtcagcc
    10321 gggactgcgc ggcctcggtg agcgcgcggg acagtgcgat ctgcgggtcg aagtggcagc
    10381 cggatccggc gaaggtgatc gggtagtcct cggaccagat gtaggcggcg cacaccggca
    10441 cgccgtacct gttgtccacg aaggcgatct cgagccacat gccggcgctc gtgaaccggt
    10501 cgaccaggct gcggcagtac gggtcggtca cggtgaccgg gtcgaccagc gtgcgcagct
    10561 ggctgccgct gacgtagtcg tggtgcagta cgtcgcgttc gatcgtctcc agcagtgcgt
    10621 gcaaggtggc ttcgggcagc gtgttaccgc aggccagacc gttgctggtg acgtggaaga
    10681 cttccggttc cgccgcgctg gggtgggtct tgcgccgtac gacgtcggcc gggacgagca
    10741 ccggctctgc ggagagcagg ctgtggccgg tgacccagtc cagcgcgaca tcagccagcg
    10801 ccggatggtc gatcttcaca ggcagtgcgt gcatcgggta cggcaggtcc aggtcgcggt
    10861 gcgtcgcgcg gatgtccgcc ttcaacggct gctctgcgtg gaagagttcg gcggactcca
    10921 ggactgcgga gatcttggca agggtgtcgg tggctccctt gccctgagag gtgaccaggg
    10981 tgtgagcgtt gggccgtacg gccgtccaca ctgggatgcc gaggtagtcg aggccggtga
    11041 gccgggcaac gcggctgatg ccgagccgtg cgatgtgtgg cttcaacgcc tcccaggtct
    11101 cctcggaggt gcgggtgcgg acggtgccag tcagggtgat cgaggtcatc ggcgggccgc
    11161 ctcctgatcc ttgaggaagc cgagcacgaa cggccgcgct gcgtcgacgg cttcgcggac
    11221 gccgtgcagg ccgcgcaccc acgcctcctc ttccagtccg tccgggcccg ttccccacac
    11281 tgcggccagc atgtcgcgca ccacgctctc cttgatggcc tctgggaaga agccgcggtt
    11341 cgcctcgcgg gcctggtcgt tgacggccga gtaccgagcg acgtcggtgc ggtcggttgg
    11401 cgtctctcgg atcagcaacc gggctgcggt ctgttcgtcg gacaggtcca cgcgggggtt
    11461 gatcactgcg caggcgacgg tccagggcag gtcgcttgtg ccgaggctga tgaggtactc
    11521 ccaccacacc tgcttgaacc gggggtcgaa gatctgctgg aaggtcaccc gctccagagt
    11581 gcggagccgg ccgtgctctg tgtcgagcgc ggcgaaggcg ttggcccact gccgaaagca
    11641 tcgcgtcgtc cacgtcaggc cctccaccgg ttcggccggg gtcttggcca tctcgcgcgc
    11701 caggtcgagg gcgtccaggg cgtcctgccg cttcacgtcg ccgaagtgct cgtcggtggc
    11761 cagctcgtgc gtcagccagt cggcgaattc gggcaggttc tctcgccggc tgacccgcat
    11821 gaccgcatcc agcgatcggt gcgcgtagta cacgtcggcg agcgtgccga gcagccggtc
    11881 ggcttgggcg gcgtcgacga cgttcttgcg gagggcgtgg ctgaggacct ggcgcaccct
    11941 gaccaacggc cacgtgcagg cccgcgggtc accgcccgcc aactgcgcga cggccacctc
    12001 gtcgtcgccg tcgagcaggc cggtgttgta gtcgtgccag accgaaccga tgccgatcat
    12061 gccgcaatcg gacagttcgg ctgcccgtag agcgccgatg ctcgccgcgc cgatgacgcg
    12121 gatgccccgg ccgagtgtcc agatgatctc cttgtgccgg acggccggcg aatggtggta
    12181 gacgccgtcg atgatgacga cggtgtcgcc gaccgtgatc tgtggatcga ataggtctcc
    12241 gtgccggatc ggcggccgta gccgtaagtc cggggccttc agggctggtt cgtccgggct
    12301 cagcgtaggc ccggtgaaga cgtggatcac gtgatctcca ggatggggga cgcgcagatg
    12361 agcgggcgtc cggccaccac ggtggccgga cgcccttcga gcccggatca gaaggtgtag
    12421 cactcgtcct gctcgacgtc ctcggaccgc acaacggccg aggtatccac cagctcttcg
    12481 acgtcggtgc cgtcggcgac gaccgccgtc gactgtgctg cttcctgtgc cttggacatg
    12541 ggcatcctca cttcgctgat agttgggtcc gcccggagga cacttcgtct tccgggtcct
    12601 gcacccggcg tcggccttct ggcgcgtcgg cgccggggtc ctgcccgctt cccgatgccc
    12661 ggcccgtcat cggcgagcgg cccggaagcg gtgttcatgg ccgtcccctg tggacatccg
    12721 gtgagcccgg ggaacgggat gagtcagttc gtacggaggg ccgctgccga ctcctccggc
    12781 gcagcctcgc ccaggcacga acgggggaag agagtcccgg tggctgccgc tcatcaacac
    12841 gcccagccag ccatggctcc tggtctgctc acgccgggcg gatgtctcgg gcacgtcagg
    12901 tcaccaggcg ggccactacc gtgacggcga ggccgaccac cagcgcgtag gcggtggtga
    12961 cggcccaggt gaggcgcggg tgccgacggc gcatgatccg ccaggcctcc cggccggtcc
    13021 ggccgtcggc gtgcgccagg attccgaggc cggtgagaac gatcgacacg tactgagcac
    13081 gcgaaggcga aggcgattcc atcgggctcc tcatcaagat gacggggtca gtaggcggtt
    13141 cgtgatggcg caaggtgacc agggggcccg agcgttggaa cgtacggcgc gcgaaatggg
    13201 cctgggcctt gcgctctatc gcggtcaggc atggctcgca caagcggaac gggccgtgct
    13261 ctccgtccca ctggaccggg cccacccatg tcacgggcac gcctggggta tcgcagcgcc
    13321 agcactcgtc aacggtccat tcgatcagca ctggggctcc ctggatccgc gagacggaca
    13381 gcggccgcag cggcctggac tgccgcgagg tacggccgca gaaggtcatc accggagggc
    13441 aatccgtccc ccggcgggac gctcgcctcg cgttgggcag gcggtatgag ccagctgcgg
    13501 gcggccatca tcttcggtac atggacggtt ggaggcggca ggagaagcag ggcgccgcgc
    13561 cggaggagca gggagtttgg cgcacaccag ccgggtgcgg agtccaggcg gatgatgacc
    13621 tcggcgccgg acggtccgag gatgactggg ccggggtgga ttcccgccgc acgcacacgg
    13681 tcgaggacgt cccgggccag ggcaccaggc acgagaatgg tgtcgaagga caggcccacg
    13741 gggacttcgg ccaactgccg gcggccccat gccgtcagga cttggtcccg gcgcccggtg
    13801 ggctccagcc agttgtaggg caccggcccc acggcggcgg ccgtcagctc ctgagcaggt
    13861 gcagagcgcg gcctcgggag ggacggcgcg gccatcaccg tatgggtgct caccggatgc
    13921 ccccttccgt ctggtggccg tgcatgatga ggatcacgag ggcacccatc acggccagca
    13981 ggaccaggag atagagagcc tgggcacggt gggtgtgcca catacgcacc tcatccggct
    14041 gccactgccg atggtgctgc tcagaaggct ccggcacctc caggtcggcc cagacgcgtt
    14101 tgccccaccc cagagggtca atcccccact cgtgggcgac tgcggcaacc agggccagac
    14161 cccggccttc ttcagcctcg tcgtccatgg ggcgcagcac cggttcggcc gtgctcttgt
    14221 cgatcacggc cagtcgtacg cggccgtcgt ggcagcgctg caccttgacc cggaacaccg
    14281 ggtaccgagt gtgctgaacg gcgttggcgc tcagttcgga gatgatcagc tcggccgcgt
    14341 ccgtgagatg cgtcagctcc caggccacca gggcctccct cacgagctgg cgggccttcg
    14401 gcacggagcc gggctcacgc ggcagcacgt cggtgaccac cggcgtgccg tcgtccgcct
    14461 ccagcacccg aactgcacga cgatgacggt tcctgagcat ggtgtcactc accgagcgcc
    14521 ctttcgccgt gcgcgcgctt gaagcagccc gaggggtctg cgggtgcatg agggacgaat
    14581 ccaggtcgtc ggcgtgcgct gtgcgcatgg cacgacctcc tctgggggga ctggtgagcg
    14641 agcgtcagag acgggcctcc cggtgcgtga gcaccggttc ggcatcggca acggcggaag
    14701 gccacggcgt gcactgcctg ctcctcgcct cagtggctct gaagcgtgtg gacgagcgcg
    14761 ataccgaagg cgaggaccac gaggctgacc agcgcgatcg tgatgaccgc ttcggtgatc
    14821 cgggtccgca gcggcggctt cggtgaggtc atgagcggcg ccctccgtgg tcgctggtga
    14881 cgttgccggc gttctggcgc cactgagttc tccctgtggt cggctggagg aaagcgatga
    14941 aggcgtagtg gcggtgcagc caatgcaggt acgcctcgta ggcctcgtca gtgctgggca
    15001 tggaatcgcg tcccagcgcg aggacgccgt cgacgaagcc cgacccggca cggcggaccg
    15061 caaggttgaa ctgaggacgg gtggaggctg agccacccgt cggttcgtcg gtgaagcgct
    15121 ctcgatcgac gctccaccca cgctcgcgcg catgctccgc caggagggca tgcgtgccgt
    15181 cggtgtccac tcccaggtcc gcgaagacgt aggtggtcac cttgatggga cggccgggtt
    15241 tgatggcggc gagggcattc tcgaagacgc tgcgtcgtaa ggcggtcagc ctgccaccag
    15301 gggtcggacg gaaccggggc tccacaggcc tccacctcag ccacgactcg tcgagttcgt
    15361 cggccggaac gggctgaagc ctcatgaggc cctcctgcac aactcggcga agcgccggct
    15421 ctcctcgtcc tgtagccgcg ccatgaggac cgggcggtgc acagggcgca cggagtacac
    15481 gagagcaacg ccgacggggc cgagaaggtt ggtcatgcgg gcacctcccc cggcaccatg
    15541 cgggctcgga ccgtcttggt gcgcccgtcc tcggccaggc tccaggtcac ctccgccccg
    15601 agcaggcgcg cctcccgcag gccgcgcccc ttctcaccgt tgagcgccgc cgcactgtcg
    15661 cggaactcag gagacggatc ctgaacgtcg atgcgcagtt cgtcgtcctc cgtcaccgcc
    15721 aggaccacgg tcatccgcgc atcggtcccg ctgtcggtat tggcatggac gacggcattg
    15781 gccgtgagaa tcgcgaggac gcggaccgcc gccatgatgt tcccgggcca gcccagaacc
    15841 gtgagacggg tgatggcgtc cgtcctcacc tggcgcaggc cggccaggtt gagtcgatac
    15901 gagcgggaca gctggcgatc gacaggcgcg ccggcaccgg aaggcagcgc gacggcacct
    15961 gccacgtcgg gcgtgcgcag gcaggatccg gcctgcgggt acacagcgaa cgccgggata
    16021 cccagcagcc agacacgtaa ggcgatgcgg tcccccggat accaagcgat ctcctgctcg
    16081 gcgggggcga cgactcccgt cgcggcgccg ctggtcaact catgttcgac ggtgcgccaa
    16141 ccggtccggc gctgacgagg ggtgtcgagc gcggccaggt cgtacaggtc gtgcacgaca
    16201 ttccagcccc gccgggcggc gaagtcgtgg aggaccgcca gcgcacggtt cgctatctgt
    16261 gagtcgaacg cacacgtgta gagcacgacg ctcgcgctgt cgctggccgt atcacctaga
    16321 ggcggtacgg gcaggtctcc ccaaacgacg gcgggagcat cggtctgaag tccagatgtg
    16381 ggctgtccgg tcatggctgc tgccatcgac aacggggcga aagcgcacgt gtgcaggtcg
    16441 gcggccgcag gccggttcgt ggacaaagct ccgcccccat tcgatcaacc ctgtgacatc
    16501 gcagcgttac atcgcgtagt gcaagcccaa ttagaatcct ccatgcaatc ccatgaggca
    16561 agcccagctg agaaatcgtc ccctgacgtg ggacctccga gaagggtgat ggggcgtgac
    16621 tgacggccgt acacgcgatg aggcacactt gcaccgggca aacccactac gacagcgcag
    16681 gcggggaggg cgaggggtga gcgatccgaa cgggcccacc gtgcgacggc ggcgcctggg
    16741 cagcgagctg cgacgactgc gcgagcgcgc aggcctcgac cagctcgcgg cagccaacca
    16801 cctggaatgc tccacttcga agatctctcg tctggagcgg ggccagggcc tggccaagca
    16861 aatggagatg cgcagccttc tcgatctgta ccgcgtcacc gacgaagacg aacggaccgc
    16921 gatccttacc ctgcacaaga cggccgccga agtcggctgg tgggaacagg ccgagtacga
    16981 agaggtcttg ccgagcggtc tgggggttta cgtcgggctg gagtacgacg cccgcgccct
    17041 gcaatgctgg gaactcggtt tcgtgcccgg ccttctgcag actgcggact acgcgcgagc
    17101 ggtcgtctcg tcactgcctc gcctctccac cgacgaggtt gaccggctcg tcaaggcacg
    17161 catgcagcgc caaacccgcc tcacgcagga gaaggacccc ctcgaactct gggccgtgat
    17221 cgacgagtcg gtgttgcatc ggccgctggg cggcgccgac gtcatgcggg cccagctcga
    17281 cgccctcgcc gagtggaccg cacgcacgaa cgtcacactt caggtctacc gccccaagga
    17341 cgtgcaccct ggcctgcgtg gttcgttcag cttgctggaa ttcggccccg ccgacccgcg
    17401 gatcggctac gtcgattcgc ccggcgggaa cgccttcctg gagaaggaca aacaagtccg
    17461 cgtccttgcc gacaccttcg accgcctccg ggcgggtgcg ctcgaccccg aggagtccgc
    17521 ggcgctcgtg agatctctag ccgcagagga gaaatgatca tgaaccatcc cgcccagact
    17581 gcgctcggcg ccgacacctt ggcctggtgg aagagctcgt acagctccga gcaaggtgcc
    17641 tgcgtcgaag tcgcgcacgc accgcagggt cggatggctg tgcgggactc caaggtgcat
    17701 gcgggcccgc atctgctcgt agacacacat gccttcaccg cgctcgtcgc cgggctggtc
    17761 accgggactg tctgaaacga acatgcaagg ggctgcccca gcggggcagc ccctttgtcg
    17821 tgcacagatg ccgtgcaact ctggtcgccc acctagccag cccggatcgc tcgccggcct
    17881 tctctgcgcg gatgagagtc agtgtcggtg gtcttcgcac cgcccagggc gaactcgctg
    17941 catgacgggc ggtgctggcg gaccgggtct cggaaatttc ccggcttggc tgtcacatct
    18001 gcccagcggc acctcccctt ctgtgggtga gggcggcaca aggccgcctt cccgaggagg
    18061 gagaggctcg tggtgggtga tgtggtgccg caggcgccgg gggtggtgca cggttttgtg
    18121 ctcgtgctcg gcgccgttgt ggaacacgtc ggctggctgg ccggggcagc cggggcggtg
    18181 ctgatcatct gggctgcgtc ggcggcctgg tggcggcgcc gagccgtgcg ggagctggag
    18241 cgccgggccc ggttcgagct ggttccggcg gtgacgttcg atccgcagat gggggacatc
    18301 gggcaggctg cggcacggct cgacggggcg cgagcggccg ctgggggtgt accgaagcgg
    18361 gcgggcgcgg tgcggatccg tgtctgggcc gggccggaga gccagttgca ctacgggtgg
    18421 gagggcccgg agcgggcggc gagcgtgctg cggatgccgg gctaccggca ggtggaggtg
    18481 cgccccgtcg acgccgcccg gagtgcctcg acgcaggtgc ggttcgaggg cgtgtctccg
    18541 caggcgggtg gctggtgagc gcggtcgttc tgtccaagca gggccaggcg gccgtccccg
    18601 aggccacccc ggtgcctggt gtctcgcgag gcctgtatgt ggcgcgggcg gagctggtgc
    18661 tggcgcgggc ggatcactgg cccttgggca agccggtgct ggatccggat ccgctggagc
    18721 aggtggcggc ggcgttcgcc gaggtgcgca ccgaggacgg ggaagaggcg gaactcattg
    18781 tcgacctgtt gcccgtgccg gggccggcgg tggcgcggcg gcgccggcgt ctgctggctc
    18841 gggcgtcgcg ccgggggccg acggcgttcg gggaagagct gacggtcggt gggagcggcg
    18901 gcagtgtgct ctcccaggtg tgggatgtgc tcaatggtcc gagcggcaag cggacaagcg
    18961 ggggcgcggg ggcgcggctg ccgcggcaga gtgacctctc ggacgggatc ggcaagttcg
    19021 ctcccggcgc gcaggtgttc gctttgcagg tgctggtgcg gtgtacggcg cggcatccgg
    19081 cacgggcgcg ggcacggctg catcaggtga tggctgcctt gcaggcgttg cgtgggcaga
    19141 acgccctcgt tccggtgggc ccgcgcctgg gcgggtggcg gccgtactcg gatgtgtggt
    19201 ggcgccgccg cgccttcgac cggcgctttg cgcgcgggga cttcgcccca gcccggcgca
    19261 ggcagtgggt gacctggcag gaagtggccg cgctgctgaa gccgcccagc aggcactgca
    19321 ccgcgcagaa catcacacgc accggcggtg tggtctcacc tgccccggcc ggcctgccca
    19381 cctggacggg gcagaaggac gtcctgccgc tcggctacgt gaccggagcg gacggccgac
    19441 gccggctggg gggcgcgtac gcgaaggacg tgctgttcgg gtcgtccctg ggcaagtccg
    19501 ggttcggcaa gaccgagctg gcgctggtgc agttcgctgc ccgggcctat gccgaggacg
    19561 gcgcactgct gttcgacccg caccggacgg cctggctgag gatcaagcca tatctggcgc
    19621 atcccgtact cgccgaccgg atctgggagg tcgacctgtc ccgggcacgg gatgaggatc
    19681 tgatgtcgtg ctggaaccca ctgtccatgg agggccggcg cctggacgag gtccaggaga
    19741 tcgtcggcgc cgtggtcggg gcgatctcct cggcacacag ctggggagag cgtgccacac
    19801 gggcacgcac gatcctgtcg aacgcggtgc gcaccctggc tgagctgtcc cacctgctga
    19861 tccaggatgg ccaccccgag ttgcagccga ccgtgttcca gatcagcacc ctgctcgagg
    19921 acgaggactg gcgcaaggcc gtgctcgccc acctgcctca ggccaccggc cgctactgga
    19981 cgcggtcgtt cgccaacgtc gagccgaacg cgatgaacac cgtcaccaac gtgctctacc
    20041 gcttcagcag ctcccgctcg ctgcgggcgt tcctcggctc gccccgctcc ggctacgacc
    20101 tgcgccgggc gatggccacc tccgcagtgg tcggcctgtg cccgtccggg accggcgaaa
    20161 gcgacgagct gatctgcgcg ctgctgctgt tcgacctgtt ccgcgagggc atggcccgcg
    20221 cctcactgcc cgccgaccag ttgcacacca tgtggtcctg ggtggacgag ctgaccagcg
    20281 tagacggcgc ctcacacggc tacatcgcca agatcctcga gcagctgcgg aagtacgagc
    20341 tgaggttcgt ggggatgacg cagatggtca tgcggctgtc ggacaccacc cgtcaggccc
    20401 tgatgcagaa ccagagctgg ctgtcggcga ccggcgctga cgcggacgag gccgccttcg
    20461 tcgccaagcg catgcccggc atcgacccgg cgaccatcca gcagatcgac cgctactgct
    20521 acatccagtc cgtccagctg cacggcaagc gcaccgcccc gttccgggtc gaaggcgtcg
    20581 cggtcgacga cgtcttcgcc gactactaca accccgacgg cctcgaggcg ctcgacaagg
    20641 cgatcgacgc caacgtccag cgacgcccgg tcggcgacat cctcgccggt ctcgaccgtc
    20701 tggacgacgc gatcctcgcc cacctcaccc gccgcccctc cggcggcacg ccgcgccccg
    20761 cgggctccgg cgacgtcgtc caccgccttc ctcgccccac acacccgacg cagaaaggct
    20821 gaaccgcatg tccgcacccg ccctgacccg gccgcgcgct ctgtcccgcc tcgcccagga
    20881 gctgctgccc gtcctctacc agcaccggct gctgaccgcc gagcagctca cccggctgct
    20941 gcgccccacc gctacgacca gccgttacgt acgcaagcaa ctgctacagc tccaggtcca
    21001 cgatcttgca gacgccacct gccgccgcca cagccgcgcc ggcgagctgc tgtggtacat
    21061 caccccgctc ggcgccgcca ccgtcgaagc cggccgcgaa cttcccgcac gcccctacca
    21121 gatgaccagc caggccgccg cgagcgccgt gcaggagcac accctcgcca tcaacgacac
    21181 cgcgctggcc ttcgtcgcac acgcccgccg gctcggcgac ggatgcggtc ccctgtcctg
    21241 ggacatggag gtcgcccacc gcgtccgcga cggcaacacc cgctccggcg acgaggcctg
    21301 gctcaccccc gacgccgtcc tccactacac ccacaccacc cgaggcggcg agcggatgct
    21361 gctcgacttc ttcctcgagg tcgaccgcgc caccatgccc gtggcccgcc tagctgccaa
    21421 gctccacgcc tacgcccgct acgccaccta catcccccag cccgcccccg gcgcccggca
    21481 cagcacagcc ggcgggctgg tgcaggaggc ctggcgtgag cgctaccgcg ccttcccccg
    21541 gctcctgctt gtcctcaccg gcgccccgac acacaccctg gccacccgcg ccctggacct
    21601 gcgtgcgctc gccgccgccg atccccgtct tcagcgcgcc gccgcccagc tgcgggcggg
    21661 cgtcaccagc ctggaactcc tcacccgcca cggcccgttc gccgacatcg tcacccctct
    21721 tctcggcccg gacaccccga cgactgtcct ccttccggcc ccggcggtgt ccgcgtgagc
    21781 gcctccgtct cctctgctcc gttcgtgccc gcccctacgg cgaaaggttt ctcgatgctg
    21841 ctcggcaagc tccgacgacg ccgtcaggcc gccgccacgc gcacactgga aaggccctat
    21901 gcgacaccgc acgcgtgctc ggcggtagtc gacggccttc cccagttgga ctccccgctc
    21961 gtcaccgaac tcatcgccct gcaagcgcac acccgccacc tgggctggct cagcgctcga
    22021 gaacagtgcc ccgaggagta ccggcacctc gcccgtctcg tcctccagca cgtcctggaa
    22081 ggctggcacg cccagaccgg cggtcgcggc cggctcgagg acctcctcgt ctttccggat
    22141 cccgccggtc ctgtccccgg tcactgtcag catgagcgcg accacatgac aacgtacggg
    22201 agttgaccat gcttcttcgc cagcacgccg ctgccgcagc cgtcctcgcg gccaccgccc
    22261 tgctcaccgg ctgcggtcac tccgggggca ccgtgggctc aggccagccg tcccgtaccg
    22321 cccggcccag
//
