LOCUS       NZ_CM002285            22769 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9386951
            Orig. end                         :: 9409720
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22769
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="45"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22769
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22769
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12769](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12769
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            86..961
                     /locus_tag="M878_RS50330"
                     /old_locus_tag="M878_44110"
     CDS             86..961
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013501.4"
                     /locus_tag="M878_RS50330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44110"
                     /product="hypothetical protein"
                     /protein_id="WP_023553633.1"
                     /transl_table=11
                     /translation="MAQTKLDKQAEETAESRMFCIGRILAGRDLDGVKRTRGHLLAFRK
                     PRPARSGGAVHPAAPTGVTVTRGACRTGSPQGAVAHSYGILTPYQCNKMFKEGKLAACF
                     RIVTEVGEPHLAQAEALGRAFQEAIAPATVNYDFGHIRDAAAMLPDSEIVKMVRGWGLQ
                     EEAPVLVMALSLKEAVRQALPPEAAEASFWDTVERDLVDAFTGLAAQEGEPGLAYYEEG
                     PDQTSYYRDLFFALQDEQAGAYLYAVAFCADVTVGFGKSRVGTLSLTDTAPFAVRLNAI
                     VVRQKLANVA"
     gene            1063..1368
                     /locus_tag="M878_RS90260"
                     /old_locus_tag="M878_44115"
     CDS             1063..1368
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024980.4"
                     /locus_tag="M878_RS90260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44115"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_023553634.1"
                     /transl_table=11
                     /translation="MAALASVEPPKPPKLSDSRFAEPERELARGPAVHGWEDRRWTLAR
                     TRVLIARKFRLDCSSAVVWRLMHRHGWFWQCPARRALERDEQAVGLWKKDVWPQVE"
     gene            complement(2151..3119)
                     /locus_tag="M878_RS90270"
                     /old_locus_tag="M878_44130"
     CDS             complement(2151..3119)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS90270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_44130"
                     /product="PD40 domain-containing protein"
                     /protein_id="WP_023553636.1"
                     /transl_table=11
                     /translation="MTTPITVAWALAVSCGLGTTAATAATASHHIRNGQIATDYGAEVI
                     YLQNTDPVTGATSDIGAPNRIKGCNLAASQDGKTLVYSTVCGYFTDRGGDTVSVMNRDG
                     TGQRVVWQMPPDFGNRQSVVGNPAISPDGKRILFGTFPHGPSQTRYWTINTDGTGLAPL
                     DLGVSTAPDGVPRFSPDGRTLAFTVGGVIWLKKGNKPAAPLTVRKPGLPNDPYGWLRWS
                     PDGRHLVFADGKGLYEVAANGSTWRTLVTSPNSTTGYLEPTYSPDGTQLAFMSITPSGD
                     RGGDLLRSIVGLTLARPGTPRTILPGNPAYQVADPVWLPAR"
     misc_feature    complement(2340..2342)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4311..4327
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.39"
                     /tool="antismash"
     gene            4426..5928
                     /locus_tag="M878_RS90280"
                     /old_locus_tag="M878_44140"
     CDS             4426..5928
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563150.1"
                     /locus_tag="M878_RS90280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44140"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_023553638.1"
                     /transl_table=11
                     /translation="MLTRGDAQPCLRLFAAGPVGGIAAAAATLLIALSGRYGFHRDELY
                     FLLAGQHPAWGYPDQPPLTPLLARLGAELFGSTPTGVRILPALLTAVTITLTALVAREL
                     GAGQGGQVLAAGAAACSGYTLGIGHLLSTATFDLTVWLAIILLTLRLLRTGEFRWWPSL
                     GALVGIALLNKLLVLGLLPALALGALTAGPRGFFVPRPRALLGPLTAVLAALPFAIPTL
                     WWQAVRGWPELTVAHAISADVGIGGRLLALPMQLLQFSPVLAPLWLTGLSRLSRRPELR
                     WARPVAVAWVVLCLLVLAGGGKGYYPIPLLYAISAAGCEPYAHWIREHRARLAGGLLAA
                     LLTSALAALPVLPASALTVPMAVDPDLGEEVGWPQLARATATGWEAIPADRRATAVLLT
                     ANYGEAGAIARYGPALGLPASYSGHMGLHAWGPPSATATGPVLLVHPAGYPELEQHFTA
                     CHTVARVDNGHGTANQEQHAAVVLCAGPDRPWPVLWPLLRRY"
     gene            complement(6578..7333)
                     /locus_tag="M878_RS90285"
                     /old_locus_tag="M878_44145"
     CDS             complement(6578..7333)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360062.1"
                     /locus_tag="M878_RS90285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44145"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_023553639.1"
                     /transl_table=11
                     /translation="MAGRGSAVRKPDEDPFPGRSVLEGAFALLETLAERNEAGLAALVA
                     GSGLPKTTAYRLLEQLTELGAVERHGTCYRVGSRIFRLGRQWQPHPGLRAAARQPLQRL
                     AGTTGASVCLCVLREGRTMAATGISGMVDELAPLQAGATWPWTTAAGKLLVATGPPAVP
                     LGPLPTSWKREAKAIQESEVAVDREELIPGVCCVAVPVSLPRGKVVGALCAMVDPAQDL
                     RRLARIVTQASRAVGAVLCDGRATALGAR"
     misc_feature    7645..7660
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            8336..8740
                     /locus_tag="M878_RS000000100825"
                     /old_locus_tag="M878_44160"
     CDS             8336..8740
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS000000100825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_44160"
                     /product="hypothetical protein"
                     /protein_id="WP_023553642.1"
                     /transl_table=11
                     /translation="MKTLTVTGPGIEFPYAAQVARIVRHRAGAKTGKRTRETVYVIPDL
                     TSRQATPERIAKIIRSRLVIENRLHFVRDTALPRGRLPSPHRTRPREPGHPPQPAINPL
                     LAAGHTNIAAALREMSLRPFEWPLNVLGLS"
     misc_feature    8747..8763
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            8950..9945
                     /locus_tag="M878_RS50345"
                     /old_locus_tag="M878_44170"
     CDS             8950..9945
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="M878_RS50345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44170"
                     /product="radical SAM protein"
                     /protein_id="WP_031227303.1"
                     /sec_met_domain="PF04055 (E-value: 9.2e-14, bitscore: 51.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.7e-08, bitscore: 33.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYSCPLRCTHCYSESGRRPSRQLDHAQLLQVTDALISLRPLGIA
                     LTGGEPLLVKGLLEVAGRITRAEIPVVLYTSGWNVDRALAEELLKVFHRIAVSLDGATA
                     GVHNRIRGRARSFESALSTLSLLDEASRDLAAQLHAHVGTFGIDCSLMRSNIHQLEKFC
                     TDIVPRFPAMRHLVFGVTVPSGLANRAGFAERELLDDALIRRTASAWQLKRLQSLAPGT
                     LDITVEDNRMLMMHPDDLAKGWALPAMQVEPDGGVRAMPIYEGTVGNILDEDPNALWKK
                     AVARRSDPFVVETLTPVRTMREWAEAARRIDHHFGTAEDRARIARRPEYR"
     gene            10001..12769
                     /gene="lanL"
                     /locus_tag="M878_RS90295"
                     /old_locus_tag="M878_44175"
     CDS             10001..12769
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="M878_RS90295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44175"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_078630530.1"
                     /sec_met_domain="Pkinase (E-value: 4.3e-17, bitscore: 61.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-49, bitscore:
                     167.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPGRIAERSLLVDCVRSVLSRHQPHEWQIRPGEFWCHVRLPEAS
                     ARIQGWKLHISATPLSAPLVLARTAEVLADHHCPFKFAGTLSRVAELCARQTARSSGGK
                     FITAYPDGDDDRLRALAEELHRVTEGLPGPGILSDRPYRPGSLVHYRFGAFQGVPMLGN
                     EASYEVMLMAPDGSLDRDRREAWFSPPPWAPRDPFTGQRPEPPASGTTAPRPVRLNDRY
                     VVRDVVRHAFTGGVYRATDERDGRSVIIKQARPHTGATATGTDICNARRHEAAMLEHFA
                     SSGRTPQLVALFEQQGELFLVQEAIAGVTLRQWVAGNITLEAVDDGGGEWGLPMALAER
                     LATGLADLVELVHCEGFVLRDLNPNNVMVTEDHQLRLIDLELLSRPGERVVHAHTPGYA
                     APEQAAARACDGCPDPTADLYGLGATLLYLLTGVDPLLAPDDPPARPGRQRIAGLLDQL
                     SRDNPAAQRYAPLVLALLHERPEERPGLADVRRALSGQARPAPPAVSTAVPRRPAGPEL
                     KQLTGDALEHLLATMTPDADRLWPPSPFGATSDPLNIQHGAAGVLGVLARALRAEPGAE
                     LREAVATAAGWIVRRTGREPRALPGLYFGRSGTAWALLDAAEALGDDTLADTAADLAHR
                     IPLRWPNPDICHGSAGAGMTQLRFWEATGDQDFLRRAGEAAESVAAAAVRRDDRLLWPI
                     PRDWPSNLAGLVHYGFAHGVAGTGTFLLAAGRATGESAYTELAEEAAQTLLTTAHHDGG
                     AAYWTAGPSGGARKTNWCSGSSGIGTFLLRLWQQNGDARLRAGAEAAAIAVRRTRWHAG
                     TAQCHGLAGDGEFLLDLAQACGQPRHTRWAEQLAVALHTRHAIRDGRVLAPDETGTSVV
                     TDYGTGLSGVLAFLLRLRDGGPRLWLPRTLAGPYTAHTAGESGDRTGTEGR"
     gene            12775..12882
                     /locus_tag="M878_RS99140"
                     /old_locus_tag="M878_44180"
     CDS             12775..12882
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038157.1"
                     /locus_tag="M878_RS99140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44180"
                     /product="ALQxL family class IV lanthipeptide"
                     /protein_id="WP_023553646.1"
                     /transl_table=11
                     /translation="MELDVKALQHLQEEEPETGLYPCTWTCPWTSTSAE"
     misc_feature    complement(13612..13627)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            13819..14322
                     /locus_tag="M878_RS90300"
                     /old_locus_tag="M878_44190"
     CDS             13819..14322
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016413.4"
                     /locus_tag="M878_RS90300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44190"
                     /product="LURP-one-related family protein"
                     /protein_id="WP_023553648.1"
                     /transl_table=11
                     /translation="MRYLVRDRMLAFHEEAWVETEHRQRLFKVNRKLLRLRTTFDFVDT
                     EGRQMASIVKKALTFHHTILIKQDGENVGRISKRKFRIFGDRYKVTLRGGRRLRIAGNL
                     WDREFDIADDSGTLAHISRRWFTIRDAYAIDVMSEPDWLLLVILAVCVDHIIEDREGEQ
                     LTNL"
     gene            14397..15098
                     /locus_tag="M878_RS90305"
                     /old_locus_tag="M878_44195"
     CDS             14397..15098
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579012.1"
                     /locus_tag="M878_RS90305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44195"
                     /product="metal-dependent hydrolase"
                     /protein_id="WP_023553649.1"
                     /transl_table=11
                     /translation="MMGHSHAVSGALLFAGTAPYLPPVLLHTHLSPQEILMGTVLCAGA
                     ALLPDLDHHDGTIANFLGPVSRMLCRFVAFISGGHRHATHSLFFVAFATLGTWAGIAYL
                     GRPFTLGMCFLLLALAVRALNLCPPGHGFHAWGTNVALAALGTAAIAKFIPSAPDWLPY
                     AIGLGCLAHLLGDSITKQGAPWLWPLKTRYEIVLIKSSGNKLETEILTPLMGAGTIALL
                     WLTVLSPYPLH"
     gene            15383..15532
                     /locus_tag="M878_RS98015"
                     /old_locus_tag="M878_44205"
     CDS             15383..15532
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS98015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_44205"
                     /product="hypothetical protein"
                     /protein_id="WP_023553651.1"
                     /transl_table=11
                     /translation="MTDENGATHQLLDEDSMRRLADIAPDPMRAHALVDQILAEVRDVE
                     QRAV"
     gene            complement(15563..16375)
                     /locus_tag="M878_RS98020"
     CDS             complement(15563..16375)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS98020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158692868.1"
                     /transl_table=11
                     /translation="MPRYKSLPALGRRILIWIAAAVLAGLAAVISDKIVAGEKKVEEFL
                     GGKSIQATLTTATGPSLRLEADQGMGCASSGWVFPMKSSRATVPPGHGPKRNGHTWDQD
                     PAAFGAAPASPVTLYVYATGKVDHAIVLTGLKIHVTSRKPAIKGTIQNVAWGCGGGGAY
                     RYGEIDLDRKAPYWVPNPKLPGDVQADALKFPYKVTAGDPEMFMVTVNTTSCLCSWYAD
                     LTWIDGSVQGHSVIKDSGEDFHTTATQGLPGFSWSEGGARAPWTPGAP"
     gene            16538..>16737
                     /locus_tag="M878_RS95645"
                     /old_locus_tag="M878_44210"
                     /pseudo=""
     CDS             16538..>16737
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010351609.1"
                     /locus_tag="M878_RS95645"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="M878_44210"
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTDLELAIAATGLRKSYAGNTVLDGIDIRVPGGTIFSLLGPNGA
                     GKTTAVNVLSP"
     gene            complement(16755..17036)
                     /locus_tag="M878_RS90310"
                     /old_locus_tag="M878_44215"
     CDS             complement(16755..17036)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS90310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_44215"
                     /product="hypothetical protein"
                     /protein_id="WP_023553653.1"
                     /transl_table=11
                     /translation="MEIDGETVLRPVHRRHRKTKHTRLLRATVHYDLDREGSLDVNECL
                     HLPYDGIPPGLQPRNLHPGYRIRDRHPEPRQPAPRPRRTLLKRLLGLP"
     misc_feature    complement(17304..17318)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     misc_feature    17306..17326
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.66"
                     /tool="antismash"
     misc_feature    complement(17408..17421)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.84"
                     /tool="antismash"
     gene            17537..18369
                     /locus_tag="M878_RS90315"
                     /pseudo=""
     CDS             17537..18369
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890904.1"
                     /locus_tag="M878_RS90315"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPSRWSGAISFGWSPCLRPWSPLPKIVKTAHPLGCYNPRIPDRIV
                     FERVMAALVHGSGYERIAGPDCSDRTIRRRVKYWAELGLPPQLYALALRVYDRVIGLEL
                     GELSVDGCITKAPAAARQLAGPRWTGASKG"
     gene            18709..18852
                     /locus_tag="M878_RS98025"
                     /old_locus_tag="M878_44230"
     CDS             18709..18852
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS98025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_44230"
                     /product="hypothetical protein"
                     /protein_id="WP_023553656.1"
                     /transl_table=11
                     /translation="MAGSGFADELGEAFAAAVLLLFGLKYRLFSVTVDAQRTDELETDS
                     HG"
     gene            complement(18869..19390)
                     /locus_tag="M878_RS90320"
                     /old_locus_tag="M878_44235"
     CDS             complement(18869..19390)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125154.1"
                     /locus_tag="M878_RS90320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44235"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_023553657.1"
                     /transl_table=11
                     /translation="MIPSTPADTVSAWWRQARPDLDTRSMDVFGRLRRLHVLAELEAGY
                     HLSAAQLTSSELDVLITLRHADYPLIARNIAALRGCSRAAMSNILAKMEKRGLVTREPN
                     PADRRAALIRLTDEGARLTDEIFPERLAMEADLLAHLTESDRKDITQALDLLLNALLRR
                     SPLAADPEPT"
     gene            19532..20815
                     /locus_tag="M878_RS90325"
                     /old_locus_tag="M878_44240"
     CDS             19532..20815
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00710.1"
                     /locus_tag="M878_RS90325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44240"
                     /product="multidrug effflux MFS transporter"
                     /protein_id="WP_063750635.1"
                     /transl_table=11
                     /translation="MEAPLTASPPSHAAAPRRGGPVILLLALLTALTPLSTDMLLPAFP
                     EMSDGLHASTSSIQATLTSYLAGMLVGQLLIGPVSDGVGRKKLLAWGSLLFAVFSLLCA
                     VATNAALLNAVRVLEGLTGAAGMVLARAVVGDWYRGQEAAKRFTALSMIFAVAPIIAPI
                     IGGGILAVGSWRTMFIVLAILGLVLAVAVATGLPESLPPARRASGGVSQAFKGMKDLLG
                     QRPFTGYVLTFSFANIALFAYISGSSFVFQDVYGLSETMFSLTFALTAIGVLIGGALFG
                     ALSGKGVAFNKVLTMGIFVGLLATAVHLVIAVTVGNTLVTSLVFMFLSMFAVGATIPSV
                     MTIGQEIGRHTGGAASALLGAGQCLLGGITAPLVGALGTNSDKPMAVLMVVGFALATVA
                     LLGIARPREGHGEPSEPAQHATAGAGAE"
     gene            20812..22092
                     /locus_tag="M878_RS90330"
                     /old_locus_tag="M878_44245"
     CDS             20812..22092
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019640.4"
                     /locus_tag="M878_RS90330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_44245"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_078630532.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.2e-06, bitscore:
                     27.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1e-08, bitscore:
                     34.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREKTSKEHLVGEGVECQCDEGAPETWKGAPDLAAQVLCRARKAA
                     PLLREAAAEIEDGRRLPDRIVDLLGNTGVWRACMPKAWGGPDLTSMEQVELLEILAQGD
                     ASAAWCSMIAMDSGIYSGYLDPVAVKEIYHDIDLITAGALFPTGTAEKVDGGYRISGRW
                     RFASCISHADVLMASCIVHDNGVPVGDPVTGEPKQWRVFAARPDQFEIHDTWYTTGLRG
                     SGSHDYSVKDLFVPESHAFTMSLPRQDRILLRTPDAIQRKMPGIPLGLARAAIDYAVDV
                     AGGRRDRETGTPWTSDMRVHEVIGRCEMELHAARASVYTSLADQWEGFTTGKEDLRSER
                     VTTALARYHAFQTARTIVQRLYDLLGGTAVYAAASPFDRWLRDVNTMCQHAVAQDAVLQ
                     MAGVVRLGGEPPNPVNPALAVSLPAAP"
ORIGIN
        1 ctgtccggtg cgggccaacg ctctaacggt cggtgtccgc ctccaggtgt gaggtcccgg
       61 gacacagaac gaatgggcac ggtcgatggc gcagacgaag ctcgacaagc aggcggagga
      121 gaccgccgaa tcccgcatgt tctgcatcgg ccggatcctg gccggccggg acctggacgg
      181 cgtgaagcgc acccgaggcc accttctggc gttccggaag ccgcgtcctg ctcgaagtgg
      241 aggggccgtg cacccagccg cccctacagg cgtcactgtc acgcggggcg cctgccgcac
      301 cggctccccg cagggcgcgg tggcgcacag ctacggcata ctgacgccct accagtgcaa
      361 caaaatgttt aaggagggga agttggcagc ctgtttcagg atcgtcaccg aggtgggaga
      421 gcctcatctt gcccaggcgg aagccctggg gcgtgccttc caggaggcga tcgcgcccgc
      481 caccgtgaac tacgacttcg gccacattcg cgatgccgcc gccatgcttc ccgacagtga
      541 aatcgtcaag atggtccgtg gttgggggct ccaggaagag gcgccggtcc tggtgatggc
      601 gctctccctc aaggaggcgg tccgccaggc gctcccgccc gaggcggctg aggcgtcgtt
      661 ctgggacacc gtcgagcgcg acctcgtaga tgccttcacc ggtctcgcgg cgcaggaggg
      721 cgagccggga ctggcctact acgaggaggg gccggaccag acgagctact accgcgattt
      781 gttcttcgcc ctccaggacg agcaagccgg cgcgtacctg tacgccgtcg ccttctgcgc
      841 cgacgtcacc gtgggcttcg gcaagtcccg tgtggggact ctgagcttga ctgacaccgc
      901 accgttcgcg gtccggctca atgcgatcgt cgtgcgccag aagctcgcga acgtcgcttg
      961 atcctccggg catcgtgggg acgcaggcaa gcccggaccg gaccgttgcg ggtgagcgag
     1021 cgttcggtgg aacgccggcg gcgtgcctgg cgggagggtg gcatggccgc cctcgcctcc
     1081 gtggagccgc cgaaaccgcc caagctgtcc gatagccggt ttgccgagcc ggagagggaa
     1141 ctggcgaggg ggccggccgt gcatggctgg gaggaccgac gctggaccct ggcccgaacc
     1201 agagtgttga tcgcccggaa gttccggctg gactgctcgt cggcggtggt gtggcggctg
     1261 atgcaccggc acggctggtt ctggcagtgt cccgcccgcc gggcgctgga acgcgacgag
     1321 caggcagtgg gcttgtggaa gaaggatgtg tggccgcagg tggaatgact gcgtcggcgc
     1381 tgggggccta tctcgtcttc gagtacgagg ccgggttctc gatgatgccg ccgcgcgccg
     1441 gggagtaggt ccgccaagtg ccgtccgcgg agtggacggc accgcgttcg atgtcctgtc
     1501 gtacgccgtc gcgcgccaat tgaatctgtg caccgcgcgg atgcggtcgg gatccgggtg
     1561 gtggccggga gcccggtggt taccgaagac cacggtgacg tcgcgggcag gccaggacga
     1621 tcttgcgcgg gcggcgtgca ggagccaggt gggtgaggtg gccgccgaga ggaagggcgt
     1681 tgtccaggcc gccgtcaagg cgccagccgg tcaggcgtcc gctcgcggtg acccggtcga
     1741 gcatcagccc accgacgacg tggtgccggt cttgtgcgcg tgggcaatca ccttggagca
     1801 gcgggccgga gtagtggtga aacgcgtcgg cgtcggcgag caggtgccag cccggcccgg
     1861 tgccgacgtg cgtaccgcgg ttcgctgttg gtgtgctagc gccaggggcc ggcgctggtg
     1921 cggccgggga tgatgcccgc gtcccgggcg acggcctgga gttcgtgccg acggatctcg
     1981 ggtacgtgct cggggcagtg gaaggcgatc aggaaccgct cgatgcccag cttgcggtag
     2041 tggcggaccc aggcggccag cagttcggta acccgggtat ctccggcggc tgttggtgac
     2101 cgaagatgtt caccgatgcc ggccgccgag gacggctcag cgaacgagcg tcaccgcgcc
     2161 gggagccaga cggggtcggc gacctgatag gccggattgc ctgggaggat cgtgcgtggt
     2221 gtgccaggcc gggcgagggt caggcccacg atgctcctca gcagatcgcc tccgcggtcg
     2281 ccactgggtg tgatcgacat gaaggccagc tgtgtcccgt ccggggagta agtgggttct
     2341 aagtagcccg tggtgctgtt ggggctggtg accagggtgc gccaggtcga gccgttggcg
     2401 gccacctcgt acaggccctt gccgtcggcg aagaccaggt gcctgccgtc cggggaccag
     2461 cggagccatc cgtacgggtc gttcggcagt cccggcttcc tgacggtcag cggtgcggcg
     2521 ggcttgttgc ccttcttcag ccagatcacg cccccgacgg tgaaggccag ggtgcggccg
     2581 tcgggggaga agcggggaac gccgtcgggg gctgtgctga caccgaggtc gagcggtgcg
     2641 aggccggtgc cgtcggtgtt gatggtccag tagcgcgtct gcgagggacc gtgcgggaac
     2701 gtcccgaaga ggatccgttt tccgtccggg gagatcgcgg ggttgcccac tacggactgg
     2761 cggttgccga agtcgggcgg catctgccag accacacgtt gtcccgtgcc gtcgcggttc
     2821 atcacgctga cggtgtcgcc gccgcggtcc gtgaagtaac cgcagacggt gctgtagacc
     2881 agcgttttcc cgtcctgcga ggcggcgaga ttgcagccct tgatccggtt cggggcgccg
     2941 atgtcggagg tggcgccggt gacgggatcg gtgttctgga gatagatgac ctccgcgccg
     3001 tagtccgtgg cgatctggcc gttcctgatg tggtgtgaag cggtggcggc tgtggccgcc
     3061 gtggtgccca gtccgcagct gaccgcgagt gcccatgcga cggtgatggg cgtggtcaag
     3121 cgtaagcgca cgatgaatcc cccctggaac aaggcgagtt gaacgccaca ggctccgatc
     3181 gagccgcccc ctgcggccca tcgccctcgg agctgagcgt caggttaaag ggccgcacgc
     3241 gtcacggaca cccgtcgcgc acaatcagtg caaacagaac cacttcatgt ggaacgtgct
     3301 gacccttcat cgtgggatgg gagagcagtt ggacgtggcg agttcagttc ggtgcggcag
     3361 ggggtgatcc tcgtggcctg gatggagtgg cggaagctca ggtccggatc ggtgatggtc
     3421 ggagctctga cggcctgggt cgcgcggggg cggagtcctt ggccgtgctg gtaatggcgg
     3481 gcggtgactt gtgtccaggg cagggaacgc ggttgctggg acagggctgg ctggctggcc
     3541 tcgacgccca gtgggcggtg cgcgttcttc tccttgacca ggaatcgggg gtgggatcgc
     3601 tgaatgtgcc gtgcgtcggt cgtgaccacg actcccgtga ggtcgaacgg ggcgagcagg
     3661 gcggggaagc aggtggtctc gttggtgcgg tcggatactc gcagttgggt gacggtttgc
     3721 ccggtgctgg tcattgctgt cggcaggtgc tcggctggac tgtcaccgtg ccccgcgagc
     3781 cccgcgctga cttgccggcc atggcgagcg tgtcctgacc ggcagggtcg tatccggtga
     3841 gctcggccag cccgccgggg cagacgggtc cggcgagctg ccggatggtt gccgtgttcg
     3901 gtgggatgcg gatgctcagc acgccgaccg cctgtgcgcg gagtcgggcc gggctgtgct
     3961 gcggcgcgga ggtggctcac tgcccgatcg ccgcatacga cttcgcgccc gtcgacgccg
     4021 tgctcgcgcc gatcagcagc acgctcacga acggttggcg tcgcccgcgc cgacagcgcc
     4081 ggtccggcag caaccgcccc accacgccca cgctcgtgcc gcgttgacgg gccggtgtct
     4141 tggcgaggcg gacgctagca gactgacggc acatcgaagc ctgggcggtt cagggcgact
     4201 tgggaaggtc agtccggttc agctggggct tcgtcgtgtt cgtgacgagc cggcccggac
     4261 tttccgcgcg gctttgacag gctgtcggcg tacgagtcca tgtgcacagg taggtacaag
     4321 cgaacataca tggccgtctg taggagccca ggactcaccg gcgaagagcg gcccatcgcc
     4381 ttctgggacc ttctccggcc ccgtctggac tgtcagaatg ccggcatgct cactcggggg
     4441 gatgcgcagc cgtgcctgcg gctgttcgca gccgggccgg tcggggggat cgcggctgcg
     4501 gccgcgacgc tgctgatcgc actgtcgggc cgctacggct ttcaccgcga cgagctgtac
     4561 ttcctgctcg ccggccagca cccggcctgg ggctacccgg accagccacc actcaccccg
     4621 ctgcttgcca ggctcggcgc ggagctgttc ggctccaccc cgaccggcgt gcggatcctg
     4681 cccgcgctgc tcaccgcggt cacgatcacg ctcactgctc tggtcgcccg cgaactgggt
     4741 gccggacagg gcgggcaggt actggcggca ggagccgcgg cctgctcggg ctatacgctc
     4801 ggaatcggcc acctgctctc caccgcgact ttcgacctga cggtctggct ggcgatcatt
     4861 ctgctgacgc tccgactgct gcgcacgggc gaattccgct ggtggccttc gctgggggcg
     4921 ttggtcggga tcgcactgct gaacaagctg ctggtgctgg ggctgttgcc ggccctggcg
     4981 ttgggtgcgc tgacggccgg accgcgcggc ttcttcgtac cgcgtccacg cgcgctgctg
     5041 ggccccctga ccgctgtcct cgccgcgctg cccttcgcga tcccgaccct gtggtggcag
     5101 gccgtgcgcg gttggcccga gctgacggta gctcacgcaa tcagtgccga tgtcggaatc
     5161 ggcgggcgcc tgctcgcctt gccgatgcag ctgctccagt tctccccggt gctggcgccc
     5221 ctgtggctga ccgggctgag tcggctgtcg cgccgaccgg agctgcgctg ggcccgaccg
     5281 gtcgcggtgg cctgggtggt gctgtgcctg ctggtgctgg ccggcggagg caaggggtac
     5341 tacccgattc cgctgctgta cgcgatcagc gccgctggct gcgagcccta cgcccactgg
     5401 atccgcgagc accgcgccag gctggcaggc ggactgctcg cggctctgct caccagcgcc
     5461 ctggccgccc tgccggtgct gcccgcatcg gcgctgaccg tgccgatggc cgttgacccc
     5521 gacctcggcg aggaggtcgg ctggccacag ctcgcacgcg ccactgccac cggctgggag
     5581 gcgatccccg ccgaccggcg ggccaccgcc gtgctgctga ccgcgaacta cggcgaggcc
     5641 ggggccatcg cacggtacgg gcccgccctc ggcctgcccg catcgtactc cggccacatg
     5701 ggcctgcacg cctggggccc gccgtcggcc accgccaccg gtccggtgct gctcgtccac
     5761 ccggcgggct atcccgagct ggagcagcac ttcaccgcct gccacacggt ggcacgcgtc
     5821 gacaacgggc acggcaccgc gaaccaggag cagcacgcgg ccgtggtgct ctgcgcgggg
     5881 ccggaccggc catggcccgt gctctggccg ctgctgcgcc gatactgagc agccaggttc
     5941 ctctgcacgt tcacccgtag gtggctctgt actcctagcc ttttcttggt actcagcacc
     6001 atgatcaacc catgaccgcc gctcaccccg ttgccgagtg tgttgccgcc tctcaacgcg
     6061 ctggggaaca cttccaagcc ggtcttgccc aagtcacctt ccggctggcg gatcgcctcg
     6121 acgagcatgt ccgaagcgac gacgtggttg agcgctagca cctcagtgcc gctctccaac
     6181 ccgagcggca cgtggaacga tccgcccttg tccacgatcg gctgttggta gccgggacgg
     6241 acgacggagc cctggcttac tgccgctgtg acgtcgatgg gctccggctg agcacgccga
     6301 aaggcggctc ttctgctcag acgagcccga tgggcacctg actgtaggca aagaacggga
     6361 agtccgggtc ggtcgcctgc gtttccatcc gggaaccgtg gtgccaaagt tctccttctg
     6421 cctgggtcgg gtcgcccaag tctccgggca gcccagtccg accgtgaccg tagtcaagcc
     6481 gggacctgct tgctgagcga cacgttgccg tgccttggtc agggacacgc ccattcacgt
     6541 cctcggcagc tgcttccgct tcccgccttc atcgcggtca gcgtgccccc aaggcagtgg
     6601 ctcttccgtc acacaacacc gcgccgactg cccggctggc ctgggtgacg atccgggcca
     6661 gccgtcgcag gtcctgcgcg gggtcgacca tggcgcacag ggcgccgacg accttgccgc
     6721 gcggcaggct caccggtacg gcgacacagc agactccggg gatcaactcc tcacgatcca
     6781 cggccacttc gctctcctgg atggccttcg cctctcgctt ccaagaggtc ggcagtgggc
     6841 ccagcgggac ggccgggggt cccgtcgcca ccaggagttt tcccgccgcg gtggtccagg
     6901 gccaggtcgc gcccgcctgc aggggggcca gttcgtccac catgccggag atacctgtgg
     6961 cagccatggt gcggccttcg cgcagtacgc acaggcagac gctggcaccg gtggtgcctg
     7021 ccagccgctg caacggttgc cgtgctgcgg cccgcaggcc gggatgcggc tgccactggc
     7081 gccccagccg gaagatccgt gaccccaccc ggtagcaggt gccatggcgt tccacggcgc
     7141 cgagttcggt gagctgctcc agcaggcggt atgcggtcgt cttgggtagg ccgctgcccg
     7201 cgacaagtgc ggccagaccc gcctcgttgc gttccgccag tgtctccagc agcgcgaacg
     7261 ccccttccag tacgctccgt ccggggaacg gatcctcatc cggcttccgg accgccgacc
     7321 ctcgccccgc catgggcccg acccccttcc gctccgggaa ccagtcaagg cagcggggat
     7381 aaacgtccca tgtcatgggg ataaatcggc tgatgggact gccgttgggg agccagtggg
     7441 ggagtggtac ggcaggttcg gccgcgtggt cgggcccggc gcagggcgat gacaaggtcg
     7501 gatcgatctt gagtatgtgc tggtcaccgc cgtgtgacga tgcccgccgg gggtgtcacc
     7561 catgcaacga agctcccgtt gaggacggat gactctccaa gtctccgttc acaacaggag
     7621 cttcgaggtt cagtcggtct gcccgtgtct gtctggtcag ctcgcccgcc tgctggcacc
     7681 gcgccatcgc ggacttgccg gagcggcttg cgaccttggc ggatcctcgg gaccgacagg
     7741 ggaagcctca cccgttcttg agtgtgctgc tggttgcctg cccggccggt gggagaagaa
     7801 cgctccgcag gacacgctcg cccggctcgg tgcccgcacg gcgacggtgt gtcggtatcc
     7861 gggtgacacc gagcgggtcg accgtccggc ccctgatgaa ctgcacctgt ctaggcggcc
     7921 tggccgacct gcttggatgc gaccctccag aggccgaccc cctggccgta gacggcaacc
     7981 gcgggtggct cgcgtacctc cggcagtccg gccacgcccc tgctggccgc gatgacggat
     8041 gccgggcagg cggtcgccca gctgctggtg ccggacaaga ccaacgaaat caccagcttt
     8101 gccgccctgt tggaatccta cgacctggtc ggggtcacgg tgaccgcgga cgcgccctcc
     8161 atacccagcg cgatcaggcc tggtgccttg ccgaggagga gaagacccgc tgcgccttca
     8221 cggtgaaagc caaccagccg accttataca cccagctcaa ggccatgccc tgacaagaag
     8281 tccgggcgaa gtactacgac cgcagtcggg gcacggccgg ctggagatcc gcgtcgtgaa
     8341 gaccctgacc gtcaccggcc ccggtatcga attcccctac gccgcccagg tcgcgcggat
     8401 cgtccggcac cgcgccggcg ccaagaccgg caagcgcacc cgtgagacgg tctacgtcat
     8461 ccccgacctc accagccgcc aggccacgcc cgagcgcatc gcgaagatca tccgatcgcg
     8521 tttggtgatc gaaaacaggc tccacttcgt acgcgacacc gccctcccac gaggacgcct
     8581 cccaagtccg caccggacac ggcccagaga acctggccac cctccgcagc ccgccatcaa
     8641 cccactcctc gccgccggtc acaccaacat cgccgccgcc ctccgcgaga tgtccctccg
     8701 ccccttcgag tggccactga acgtcctcgg actcagctga ccagcagcga tacaagatca
     8761 ccagactttg caatcgccct ggggcctggc gtgctgttcc gctcagtgga acgcgactcg
     8821 tgcggccgac tgccgcgcca ttacggtgaa tttgtggccg gcgctccaga cggcccatcc
     8881 atgggggatg attgggaggg gaatccttcg gtgaatacgc tgagcggccc cacagatgta
     8941 atctgggaca tgacgtattc ctgtccgctg cgctgtacgc actgctattc ggagtccggc
     9001 cgacggccgt cacggcaact cgatcacgcc caactgctcc aagtcactga cgcgttgata
     9061 tccctgcgcc cactgggtat cgccctcacc ggcggagaac ctctccttgt caaggggctt
     9121 ctggaagtcg ccggacgcat cactcgggcg gaaatcccgg tggtcctcta caccagcggg
     9181 tggaatgtcg accgggccct ggccgaagaa ctcctgaaag tatttcaccg gatcgccgtg
     9241 agcctggacg gcgccaccgc cggagtgcac aacaggatca ggggccgggc ccgctccttc
     9301 gagagcgcgc tgagcacgct cagtcttctg gacgaggcgt cccgggacct cgccgcgcaa
     9361 cttcatgccc atgtcggcac cttcgggatc gactgctcat tgatgcggag caacatccac
     9421 caactggaga aattctgcac cgacatcgtg ccgcgctttc ccgccatgag gcacctggtc
     9481 ttcggggtga cggtaccctc cggcctggcc aaccgcgccg gattcgccga acgcgagctc
     9541 ctcgacgacg cgctgatccg ccgcacggca agtgcttggc agctcaaacg acttcagtcg
     9601 ctcgcgcccg gcacgctgga catcaccgtc gaggacaacc gcatgctgat gatgcaccct
     9661 gacgatctcg ccaagggctg ggccctgccg gccatgcagg ttgaaccgga cggcggagtg
     9721 cgggccatgc cgatctacga gggcacggtg ggaaacatcc tggacgagga cccgaacgcc
     9781 ctgtggaaaa aggcggttgc ccggcgaagt gaccctttcg tcgtcgaaac gctgacgccc
     9841 gtgcgcacca tgagggaatg ggccgaggcc gcccgccgca tcgaccacca cttcggcacc
     9901 gccgaggacc gcgccagaat agcccggcgc cccgaatatc gctgacccct cactgacctc
     9961 tctgtctcgc gttgtcggta ccggacgaag gtggaagccc atggaacccg gccgcatcgc
    10021 ggaacggtcg ctgctcgtgg actgcgtccg ttccgttctc tctcgtcacc aaccgcacga
    10081 atggcagatc aggccgggcg aattctggtg ccatgtcagg ctgccggagg cttcagcacg
    10141 cattcaagga tggaaactgc acatctcggc gacaccgttg tccgccccgc tggtgctggc
    10201 gcgaacggct gaggtcctgg ccgaccacca ctgcccattc aaattcgccg gaaccctctc
    10261 ccgggtggcg gaactctgcg cgcgccaaac ggcccggagc agcggcggga aattcatcac
    10321 cgcctacccg gacggcgacg acgaccggct gcgcgcactc gcggaggaac tgcaccgcgt
    10381 caccgagggc ctgcccgggc ccggcatcct ctccgaccgc ccctaccggc ccggcagcct
    10441 ggtgcactac cgcttcggcg ccttccaggg ggtgcccatg ctgggcaacg aggcatcgta
    10501 cgaggtcatg ctgatggccc cggacggctc gctggaccgg gaccggcgcg aggcatggtt
    10561 ctctccaccg ccctgggcgc cgcgcgatcc gttcaccgga cagcggcccg aaccgcccgc
    10621 ctccggaaca acggcacccc ggcctgtacg gctcaacgac cgctatgtcg tccgcgacgt
    10681 cgtccgccac gccttcaccg gcggcgtcta ccgggcgacc gacgaacgag acggccgctc
    10741 tgtcatcatc aagcaagcgc gcccccacac cggggccacc gcgaccggga cggacatctg
    10801 caacgcccgg cgccatgaag ccgccatgct ggagcacttc gcgtcctccg gccgcacccc
    10861 gcagctcgtc gcgctcttcg agcagcaagg cgaactcttc ctcgtccagg aggccatcgc
    10921 cggagtcacc ctccgccagt gggtcgcggg gaacatcacc ctggaagccg tggacgacgg
    10981 cggcggcgag tggggcctgc ccatggcgct cgccgagcgg ctggccaccg gcctggccga
    11041 cctggtggag ctcgtccact gcgagggttt cgtcctgcgc gacctcaacc ccaacaatgt
    11101 gatggtcacc gaagaccacc agctgcggct gatcgacctc gaactcctct cccgtcccgg
    11161 cgaacgcgtg gtgcacgccc acacaccggg ctacgcggcc cccgaacaag ccgccgcccg
    11221 cgcctgcgac ggctgtcccg accccaccgc cgacctctac ggcctcggtg cgacgctgct
    11281 gtacctgctc accggcgtcg acccactgct cgcccccgat gatccgcccg cccgtcccgg
    11341 ccggcagcgg atcgcgggcc tgctcgacca gctgagccgc gacaaccccg ccgcgcagcg
    11401 gtacgcgccc ctcgttctcg cgttgctgca cgagcggccc gaagagcggc caggcctcgc
    11461 ggacgtacgg cgcgccctgt ccggccaggc ccggccggcg ccacccgcgg tgagcacggc
    11521 ggtaccgagg cggccggccg ggcccgagct caagcagctc accggcgatg cgctggaaca
    11581 tctcctggcc acgatgaccc ccgacgccga ccggctctgg ccgccctcac cgttcggcgc
    11641 caccagcgac cccctcaaca tccagcacgg cgccgcaggc gtcctgggcg tgctcgcccg
    11701 ggcgctgcgc gccgaacccg gagcggagtt gcgggaagcc gtcgccacgg ccgccggctg
    11761 gatcgtccgc cggaccgggc gggagccgcg tgcgctgccc ggcctgtact tcggccgctc
    11821 cggcaccgcg tgggccctcc tcgacgccgc cgaggccctg ggggacgaca cactggccga
    11881 caccgcggcc gacctcgccc accgcatacc gctgcggtgg cccaacccgg acatctgcca
    11941 tggctcagcg ggcgccggaa tgacccagct ccgcttctgg gaggccaccg gcgaccagga
    12001 cttcctgcgc cgagccggcg aggccgccga atccgtggcc gccgcggccg tccgccggga
    12061 cgaccggctc ctgtggccca tcccgcgcga ctggccgtcc aacctcgccg gactcgtcca
    12121 ctacggcttc gcccacggcg tcgcgggcac aggcacgttc ctgctcgccg caggccgggc
    12181 cactggcgag agcgcgtaca cggagctcgc ggaagaggcc gcacagacac ttctgaccac
    12241 agcccaccac gacggcggcg ccgcctactg gaccgccggg ccctcgggcg gggcacgcaa
    12301 gaccaactgg tgcagcggct cctccggcat cggcaccttc ctgctgcggc tgtggcagca
    12361 gaacggggac gcccggctgc gagccggcgc tgaggcggcg gccatcgctg tccgtcgcac
    12421 ccgctggcac gcgggaaccg cccagtgcca cggactggcg ggcgacgggg agttcctgct
    12481 cgacctggcc caggcctgcg gacagccgcg gcacacccgg tgggccgagc agctggcggt
    12541 cgcccttcac acccgccacg ccatccgcga cgggcgcgtg ctcgcaccgg atgagaccgg
    12601 aacgtcggtc gtgaccgact acggcaccgg cctcagcgga gtgctggcct tcctgctgcg
    12661 cctgcgggac ggcgggcccc gcctgtggct gccaaggacg ctcgccgggc cgtacacggc
    12721 acacacggcc ggtgagtcag gagaccggac cggaaccgaa gggaggtgag acagatggag
    12781 cttgatgtga aggctctgca gcacctgcag gaggaggagc ccgaaacggg cctctacccg
    12841 tgcacctgga cctgcccgtg gacctcgacg tccgcggagt gatcggaccg caccaggcgc
    12901 gccggccttc tccaggagaa ctcttgggga cggccggcgc gctcgtgcac ctcgcacacc
    12961 cctgcgtcca gcgacggaag gacggcgata tagatgaacg aagaggatgt aacggacgcc
    13021 actgacaggg ccgccgctga ggtgcgggcc cttcacctgc tcccggacgc cgaaaacgac
    13081 ggcctgtggc catgccccat cacctgcggg aacacccagt ggtgaccact ccgctctgat
    13141 ctccggagca cccgcacgcc gtgggcgtcc cgtccatcaa cgggggcgga cggggcgcac
    13201 acggggccag ccggaatgcg gcggaaccct gccgttgccc caagggtccg caggccagtg
    13261 agctgtgacg ccctgttggt ctgttgcggt acatcacgta ttcactgcgg caggcagcag
    13321 cggaggggca gcacgggcgc tcggcacggg tccgcttggc ggaatccgcg atgcaaactc
    13381 tcagagcctg gctttcagcc tgccggtgcg tgtctgttgg tcagtggcct gggcacttct
    13441 tccaggcgaa gcggtacttg gtgttgaagc cgccgtgttg aagttgcgct tctcgccgca
    13501 gggagcgcat acgagggccc tttggggctt ctgctccccg acccccatag agcggcaacg
    13561 ccgttcaccc accgtagcca ccacaaccga acgaccactg ttgcccttca ctcgaccaat
    13621 cggacagccc ctagaccgaa gccgagcagc agtgccagaa ggacggtcgt ggcgcgccct
    13681 tgcggacctg ccggcgtgtg atggtcattc atgcctccat gtggtacgtg cggatgcggt
    13741 tgtcaccttg cgcaacttag caactattat cgcgacggac agcgattctt cccacctccg
    13801 gatcatgacg gggttctgat gcgttacctg gtacgtgacc gcatgctggc cttccacgag
    13861 gaggcctggg tcgagacgga acaccggcag aggctgttca aggtcaatcg caaactgctg
    13921 cgcctgcgca ccacgttcga cttcgtcgac accgagggcc ggcagatggc gagcatcgtc
    13981 aagaaggcgc tcaccttcca ccacacgatc ctcatcaagc aggacggcga gaacgtgggc
    14041 cgcatcagca agcggaagtt ccggatattc ggggaccgct acaaggtgac cctgcgcggg
    14101 ggacgccggc tgcgcatcgc cggcaacctc tgggaccgcg agttcgacat cgcggacgac
    14161 agcggcaccc tggcacacat ctcgcgccgg tggttcacca tccgtgacgc ctacgccatc
    14221 gacgtgatga gcgaaccgga ctggctgctg ctggtcatcc tcgccgtgtg tgtggaccac
    14281 atcatcgagg accgcgaggg cgagcagctc accaacctct gacccaagca catctgtgac
    14341 gctcggacat ctacgcgccg ttgacgcggc accgaatcgg gggagaacca ccttccatga
    14401 tgggccattc gcacgccgtg agcggcgccc tgctgttcgc cggcaccgct ccctaccttc
    14461 cacctgtgct gctgcacaca catctgtcgc cccaggagat cctcatgggc acggtgctgt
    14521 gcgcgggcgc cgcactgctg cccgacctgg accaccacga cggcacgatc gcgaacttcc
    14581 tcggtccggt ctcccggatg ctgtgccggt tcgtcgcctt catctcgggc ggtcaccgcc
    14641 atgccaccca ttccctgttc ttcgtcgctt tcgcgaccct gggtacctgg gccggaatcg
    14701 cctatctggg caggccgttc acgctcggca tgtgcttcct cctgctggcg cttgcggtgc
    14761 gggcactgaa cctctgcccg cccgggcacg gcttccatgc ctggggcacc aacgtggcgc
    14821 tggcagcgct ggggaccgcc gccatcgcca agttcattcc ctccgcgccg gattggctgc
    14881 cctacgcgat cggcctgggc tgcctggccc atctcctcgg ggactccatc accaagcagg
    14941 gcgcgccgtg gctgtggccg ctgaagacac ggtacgagat cgtgctgatc aagagcagcg
    15001 gcaacaagct ggagaccgag atactgacgc cgctgatggg cgccgggacg atcgccctgc
    15061 tctggctgac cgtcctgtcg ccgtatcccc tgcactgagg ctggataccg tcagcggtcg
    15121 tcgtacgagc gacgcacgag ccctccggtg tcgacgacgg tgtcacccgc actctgaccc
    15181 acgacaacgt caccctcgcc gtactcctcg accacgacgc caagacgatc acgtcgtgca
    15241 gatcggctac agctgctgac aagccaccgc cgtcacccga acaggccaga taccccaccg
    15301 ccccacgggc acgatcacca catgaacagc gacgccgacc gcaaagtgtg gctcgccgcc
    15361 caccggcatc gacacgagca ccgtgaccga cgagaacgga gccacccacc agctgctcga
    15421 cgaggacagc atgcgacgcc tcgccgacat cgccccggac ccgatgcggg cccacgccct
    15481 ggtcgatcag atcctcgccg aggtgcgcga cgtcgaacag cgagcggtct gacgcccgag
    15541 tcgtccacga tcccgctctt gatcacggag ccccgggcgt ccagggcgcc cgggctccac
    15601 cctcactcca cgagaagccc gggagacctt gagtcgctgt cgtgtggaag tcttctcctg
    15661 aatccttgat cacactgtgc ccttgaaccg aaccgtcgat ccaggtcagg tccgcgtacc
    15721 aggagcacag acacgacgtg gtgttcacgg tgaccatgaa catttccgga tcacccgccg
    15781 tcaccttgta cggaaacttg agcgcatccg cctggacatc tcccggaagt ttggggttcg
    15841 gaacccagta cggcgccttc ctgtccaggt ctatctctcc atatcgatat gcaccgcctc
    15901 caccgcaacc ccacgccacg ttttgaatcg tgcccttgat ggcgggtttc cggctcgtca
    15961 catgtatttt caatccggtg aggacaatgg cgtgatcgac ttttccggtc gcatatacat
    16021 acagggtgac cgggctggcc ggcgcagcgc cgaaggccgc gggatcctgg tcccaggtgt
    16081 gaccgttacg cttcgggccg tgcccgggcg ggaccgtcgc ccgactcgac ttcatgggaa
    16141 atacccaccc agaactggca caccccatcc cctgatccgc ctccaaacgc agtgagggcc
    16201 ctgtcgccgt tgtcagcgtg gcttggatac ttttcccgcc gaggaactct tcgacctttt
    16261 tctcaccggc cacgatcttg tcagagatga cagcggccag tccggccagg actgctgccg
    16321 cgatccagat gagaattcgc cgtccgagcg ccggcaggct tttatatctg ggcatcgttg
    16381 catccccagc tccgacaatc ccaccgatgc cagcctatgc ctgtggatct ccacgcgctg
    16441 gacgacaccc ggcaccagaa gcgggacgag ggcaccccag cggaccgcac ccggggctga
    16501 aaccacgctg aaccgccccg cccgcacgct ctgcggcatg acgacggacc tcgaactcgc
    16561 gatcgcagcc accgggctgc gcaagtccta cgcaggcaac accgtcctcg acggcatcga
    16621 catccgcgtg cccgggggca cgatcttctc cctgctcggg ccgaacggcg cgggcaagac
    16681 cacggcggtc aacgtcctgt ccccctgatc tccgccgacg gcgggcaggc gcggatctgt
    16741 ggctgacgtg gccatcaggg cagtccgagc aggcgcttca gcagcgtgcg gcggggccgc
    16801 ggcgcgggct ggcgaggctc ggggtgccgg tcgcggatcc ggtacccggg gtgcaggttg
    16861 cgcggctgga ggccgggcgg gatgccgtcg taggggaggt gcaggcactc gttgacgtcg
    16921 agcgagccct cgcggtcgag gtcgtagtgg acagtggccc gcagcagccg ggtgtgcttc
    16981 gtcttgcggt gccgacggtg gacggggcgc agcacggtct ccccgtcgat ctccaccagg
    17041 gctttgcccg gggcgtctca ccaagggctg gcagggaggg ccgccgccgg ccgcgcagtg
    17101 cctgatcgtc atgtgcccgt cgttgctcgt ggcactgaca atgctccgag tgggcgcggt
    17161 aaagccttcg cgttgcggtc aggttgcgct gcgaaggctc cgagggcaaa gcagtccccg
    17221 gtagtgctgc gcgtgtcctg aagcttcagt cgtcaccgtt gcttcggtgt cgcgccggct
    17281 tgccgggggc ttgaaccaca tcctgtccga gtcgctccgc cgattagacg tcctcgtcgg
    17341 ctttgcagcc ttttcggtgt tgtggtctag acaccaccct ccacgcattg cggtgcgagt
    17401 caatgggttc taggtaaaac ttttaaccgt cggcgggtgg aggccatgct tgaccccggc
    17461 tggctctgga gcatgtcccg cccactcctc gtcataggct ggactcagct cggggctgaa
    17521 cgcgcggagg tccgcaatgc cgtcgcgatg gtccggagcc atctcgttcg gatggtcacc
    17581 gtgcctgcga ccgtggtctc cgctacccaa gatcgtcaag accgcccacc cgctgggctg
    17641 ctacaacccg cgtatccccg accgaatcgt cttcgagcgt gtcatggctg ccctggtgca
    17701 cggttccggc tacgagcgga tcgctggtcc cgactgctcc gaccgcacca tccgacgtcg
    17761 cgtcaagtac tgggcggagc ttgggctgcc cccgcagctg tatgcgctgg cgttgcgggt
    17821 gtacgaccgc gtgatcggcc tggaactcgg cgagttgtcc gtggacggct gcattaccaa
    17881 ggcccctgcg gcggcgaggc agctggccgg tccccggtgg accggggcaa gcaagggctg
    17941 aagcgctcgg tggccaccga ggcgtgcggc gtcccgctcg gcatggtggc ggccggagcc
    18001 gaccgccacg actccccgct gctcgtgccc acactggaag ccgccaagga gcaggtcgac
    18061 gtggatctgg accgcggcta tgacagcgac aagacccgtg ccgccctgcc agagttcggc
    18121 ttcaccggcg agatcgcccg caaaggcctg cccgccccga tccaggctgg caagtgctgg
    18181 gtggtcgaac gcggtcacgc ctggatgaac ggtttcggca agctgcggcg gtgcatcgag
    18241 aagcgcagct gcgtcgtgga cttctacctc tacctgtccg ccgcgaccat cacgctgcgt
    18301 atgctcatcc gccgcgcgac tccgctctac cgctgggaca cccgccccac cacccagcgc
    18361 ctcaagtaac gcctactgcc ggactctcta agcccttgag cttaaccgcg gccactgaca
    18421 cggcagctgc gacgaaccca gaggcccggg ccccgtgctg ccggtcacgg cccgcggcaa
    18481 caggccgccg cgcggcttcc ctcggtgtgt gctctggacg gctgcgcgat ctcggtcgcc
    18541 cgtgaggcgg acggaaacgg tgctctgccc gatgggccgt catgcgtacg ggaaacgcgc
    18601 accacaggcc cgtgactggg ctctgtgccc aggggagaga gctgcgcctg ccggtctgtg
    18661 gcttgccgtg ccacagaccg gcaggcggcg tcagatgagc cggccgcgat ggcgggtagc
    18721 ggtttcgcgg acgagttggg cgaagcgttc gcggctgcgg ttctgctgct gttcggcctg
    18781 aagtaccggc tcttctcggt caccgtggac gcacagcgca ccgacgaact ggagaccgat
    18841 tcacacggct gagtgcctcg aagctctctt aggtgggttc gggatcagca gcgaggggtg
    18901 agcggcgtag cagggcgttc aggagcaggt cgagtgcttg ggtgatgtcc ttccggtcgc
    18961 tttccgtgag gtgtgcgagg aggtcggctt ccatggcgag gcgctcgggg aagatctcgt
    19021 cggtgagtcg tgctccttcg tcggtgaggc gaatgagggc cgcgcgtcgg tcggcggggt
    19081 tgggttcgcg ggtgaccagg ccgcgttttt ccatcttggc gaggatgttg ctcatggcgg
    19141 cgcgggagca gccgcgaagg gcggcgatgt tgcgggcgat gaggggatag tcggcgtggc
    19201 ggagggtgat gaggacgtcg agttcgctgc tggtgagttg ggctgcgctg aggtggtagc
    19261 cggcctcgag ttcggcgagg acgtgcagtc ggcgtaggcg gccgaagacg tccatggagc
    19321 gggtgtcgag gtcggggcgt gcctgacgcc accaggcgct gacggtgtca gcgggggtgg
    19381 acgggatcac tggtgggcct ccagcctttc cacgttgtta atcactgaac catagtatat
    19441 atctagttgt taaccactga accatagtgt aactaccttg ggttgacacc gacctgacgg
    19501 cacttcccgt acatgaaagg cgagttgacg catggaagcc cccctgactg cctctcctcc
    19561 ctcacatgcg gctgcgccgc gacgcggggg gccggtcatc ctcctgctgg cgctgctgac
    19621 cgctttgacg ccgctgtcga ccgacatgct tctgccggcc ttcccggaga tgtcggacgg
    19681 gctgcacgct tcgacgtcca gcatccaggc cacgctcacg tcgtatctgg cgggcatgct
    19741 ggtcggccag ttgctgatcg gcccggtcag tgacggcgtg ggccgcaaga agctgctggc
    19801 gtgggggtcg ctgctgttcg cggtgttctc tctgctgtgc gcggtggcga cgaacgcggc
    19861 cctgttgaac gcggtccgcg tcctggaggg cctgaccggc gcggccggaa tggttcttgc
    19921 ccgtgcggtg gtgggcgatt ggtatcgggg ccaggaagcc gcgaagcggt tcaccgccct
    19981 gtccatgatc ttcgcggtgg cgccgatcat cgccccgatc atcggcggcg ggatcctcgc
    20041 cgtcggctcc tggcgcacca tgttcatcgt cctggcgatc ctcggcctgg tcctggccgt
    20101 cgcggtcgcc accggtctgc cggaatctct gccgcccgcg cgccgcgcct ctggcggcgt
    20161 gtcgcaggcg ttcaagggca tgaaggacct gctcgggcag cggcccttca cgggctacgt
    20221 gctgacgttc tccttcgcca acatcgccct gttcgcctac atctccggat cgtcgttcgt
    20281 gttccaggac gtctacggcc tgtcggagac gatgttctcc ctcaccttcg cactgaccgc
    20341 gatcggtgtc ctcatcggcg gggcgctgtt cggcgccctg tccggcaagg gggtggcgtt
    20401 caacaaggtc ctcaccatgg gcatcttcgt cggcttgctc gcgactgccg ttcacttggt
    20461 catcgcggtc acggtcggca acaccctggt cacctcgctg gtgttcatgt tcctgtccat
    20521 gttcgccgtc ggtgccacca tcccgtccgt gatgacgatc gggcaggaga tcggccgcca
    20581 caccgggggc gccgcctccg ctctcctggg cgccggtcag tgcctgctcg gcggcatcac
    20641 cgccccgctg gtcggggcac tcggcacgaa cagcgacaag ccgatggccg ttttgatggt
    20701 ggtcggcttc gccctcgcca cggtggcact acttgggatc gcccgtcccc gggagggcca
    20761 cggcgagccc agcgagccgg cgcagcatgc gacagcgggt gcaggtgccg aatgagagag
    20821 aagacatcga aggagcatct ggtgggagaa ggcgtggagt gtcagtgcga cgagggcgcc
    20881 ccggaaacgt ggaagggggc gccggacctg gccgcacagg tgctgtgccg ggcgcggaag
    20941 gccgccccgc ttctgcggga agcagcagcc gagatcgaag acgggcggcg gcttcccgac
    21001 cggatcgtcg acctcctcgg caacacgggg gtgtggcggg cctgcatgcc caaggcgtgg
    21061 ggcggaccgg acctgacatc gatggaacag gtcgaactgc tggagatact tgctcaaggt
    21121 gatgcgtcgg ccgcttggtg ctcgatgatc gccatggact ccggcatcta ctccggctac
    21181 ctcgaccccg tcgcggtcaa ggagatctac cacgacatcg atctgatcac agccggtgcc
    21241 ctgttcccga ccggcaccgc ggaaaaggtc gacggcggct accggatatc gggccggtgg
    21301 cggttcgcct cctgcatcag ccacgccgac gtgctcatgg cctcctgcat cgtccacgac
    21361 aacggcgttc cggtcgggga tccggtcacc ggcgagccga agcagtggcg ggtgttcgcc
    21421 gcacgccccg accagttcga gatccacgac acctggtaca ccaccggcct gcgcggctcg
    21481 ggaagccacg actactcggt caaggacctg ttcgtccccg agtcccacgc cttcaccatg
    21541 tccctgcccc gtcaggaccg gatccttttg cggacgccgg atgcgatcca gcgcaagatg
    21601 cccggcatcc ccctgggcct ggcgcgcgcg gcgatcgact atgccgtcga cgtcgccggc
    21661 gggcgccgcg accgggagac cggcacaccg tggacgtccg acatgcgcgt gcatgaggta
    21721 atcggccgct gcgagatgga acttcacgcc gcacgtgcct ccgtctacac ctccctcgca
    21781 gaccagtggg aagggttcac caccggcaag gaagaccttc gatcggagcg ggtcaccacc
    21841 gctctcgccc gctaccacgc cttccagacc gcccgcacca tcgtccagcg cctgtacgac
    21901 ctgctgggcg gtaccgctgt ctacgctgcc gcctccccgt tcgaccggtg gctgcgggat
    21961 gtgaacacca tgtgccagca cgccgtggca caggatgcgg ttcttcagat ggctggtgtc
    22021 gtccgcctcg gcggcgagcc gccgaacccg gtcaacccgg ctcttgccgt gtccctgccc
    22081 gccgcaccgt aaggaaccgt atcgatgcag atagccgtga tcggccatac cgggatgggc
    22141 ggcaaagccc tcaccgacct cttcatcacc cgaggacacc aggtcaccgg aatctcccgc
    22201 agcgcgaagc cggacgcgga ccgcaagggc ctgacgaacg tcgccgcgga cgttttcgac
    22261 accgaccgta tgactgaggt cctgggcggt cacgatgcgg tggtgtcgat gtattccggc
    22321 gggcacgaag tcgacctcga ggtctactac cggcaggccg aaggcacccg ccggctcatc
    22381 aaagccttcc gccaagccca gggccgctat ctgctgtacg tgggcggggc ggccagcctg
    22441 tacgtcaagc cggacgtgca aatgttcgac gatgagcggt tcccgtcctg gtacttcggg
    22501 atcatgcctg ctgagcacct gcactggctt gcagagatca ccgggatcgg cttcttccac
    22561 gacgccgcca agcgcaagga gaacggaacc atcgcgccgg ggcataccga cctggagctg
    22621 gaggagttcg tgtccgggtg ggggcgggtt ccgctgctgg agggctgccg gatggccctc
    22681 gatctgttcg agggccgcac cgacttcgcc tggtcgttcc tgtcaccgcc ctggctgtac
    22741 cggccggggc cgggaaccgg ccactaccg
//
