LOCUS       NZ_CM002285            21959 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8223559
            Orig. end                         :: 8245518
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21959
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="40"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..21959
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21959
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:11959](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11959)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            387..>2470
                     /locus_tag="M878_RS000000101165"
                     /old_locus_tag="M878_38470"
                     /pseudo=""
     CDS             387..>2470
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1218: Exonuclease"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027705.1"
                     /locus_tag="M878_RS000000101165"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="M878_38470"
                     /product="AAA family ATPase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRLHRLDITAFGPFGGSRGVDFDALSAAGLFLLHGPTGAGKTSVL
                     DAVCYALYGSVPGARQSGQGMHLRSDHAEPRTRTEVRLDLTVAGRRLEITRQPPWERPK
                     LRGTGTTVDKAQTWLREYDATAGAWKDLSRSHQEIGEEITQLLGMSREQFCQVVLLPQG
                     DFARFLRADAEARGKLLGRLFDTQRFADAEKRLAERRRATEARVREGDAALLADAHRMQ
                     QEAGDAMELPELAPGDPGLADAVLGAAALARATARERLTIAHCRLAAAESAHTEIRRAL
                     DDVRELARLQSRFTEARQRAEQLQERAGAHHEAQRRMERSRKAEAVAPALELREAAEEE
                     HRRATTAEASVRGTLPGSYADAGASGLAAAARRAAEELGGLDAARRAEQKLVRLAEERS
                     GLDRQERADEEVLREADAWLDAWDATRAALQSRVDSAQEAATRAEQLAVQRDPMRGRLT
                     AARTRDTLAADLEDAQRRALASEQQALGSRAHWLDLKEQRLNGIAAELAAHLTDGEPCA
                     VCGATEHPAPARKVAGHVDREAEERAHKASQQADRQHTEDQRRLGVVREALAAATAEAG
                     DTPTAQLEETAAELEQEYARTRRDASVLHAAHEELRRAEREREQRLADRQQAAVRAASR
                     GHPTRDPGAGTGPAGGGVEQGTRRLGQRGRACRAAGAAGGAAHRRRRRRAHRRGHRAAP
                     "
     assembly_gap    2471..3310
                     /estimated_length=840
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            <3311..3871
                     /locus_tag="M878_RS85235"
                     /old_locus_tag="M878_38475"
     CDS             <3311..3871
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010041188.1"
                     /locus_tag="M878_RS85235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38475"
                     /product="SbcC/MukB-like Walker B domain-containing
                     protein"
                     /protein_id="WP_023552477.1"
                     /transl_table=11
                     /translation="LREEYDRVARLAALTAGTSADNERKMRLESYVLAARLEQVAAAAT
                     ARLQRMSAGRYTLVHSDDRTGRGRSGLGLHVVDAWTGRERDTATLSGGETFFASLALAL
                     GLADVVTDEAGGVRLDTLFIDEGFGSLDDQTLDEVLDVLDSLRERDRSVGIVSHVPDLR
                     RRIHAQLEVVKGRAGSTLRQRGV"
     gene            complement(3876..4322)
                     /locus_tag="M878_RS85240"
                     /old_locus_tag="M878_38480"
     CDS             complement(3876..4322)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662012.1"
                     /locus_tag="M878_RS85240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38480"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_023552479.1"
                     /transl_table=11
                     /translation="MTVYSPDATDWRILEVLQREGRASYAELARAVSMSPSAVTERVRR
                     LEEAGVIQGYAAVVDPERLGLPILAFVRLRYPNGNYKPFHDLVAATPEILEAHHVTGDD
                     CFVIKVAARSMAHLEEISGRIGALGSVTTSVVYSSPLPRRALGR"
     gene            4417..4902
                     /locus_tag="M878_RS85245"
                     /old_locus_tag="M878_38485"
     CDS             4417..4902
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240585.1"
                     /locus_tag="M878_RS85245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38485"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_023552481.1"
                     /transl_table=11
                     /translation="MITKTTQTSVNPVLRVAPAAPAEAAAYFRASLAFHADVSDVAAAL
                     AAGGDPGFAVVDTRSTESWDQGHIPGAVHLPTALVPGQAEQLLDKSVPVVTYCWGPGCN
                     GATRAALALAELGYQVKEMLGGFEYWAREGFAYETWQGPGRRDADPLTALVEGECGC"
     gene            4928..5443
                     /locus_tag="M878_RS85250"
                     /old_locus_tag="M878_38490"
     CDS             4928..5443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002899.1"
                     /locus_tag="M878_RS85250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38490"
                     /product="immunity 21 family protein"
                     /protein_id="WP_031226776.1"
                     /transl_table=11
                     /translation="MARYADPGALEWVESGGGPLIAVPETVLPFWAGADSEDLDTDYDR
                     ACEVDGYVGLLPVGDSAALVFGDEPASTSFLPDHATFVRWSAANSEAELLATVPAALEA
                     AVWGSEVHWRVPGPVLLFDSAWPGQAADRTEHLRVSLEAGTYAVRAAYVQPGPETWVGL
                     VRLTRLAH"
     gene            complement(5463..6701)
                     /locus_tag="M878_RS85255"
                     /old_locus_tag="M878_38495"
     CDS             complement(5463..6701)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888821.1"
                     /locus_tag="M878_RS85255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38495"
                     /product="cytochrome P450"
                     /protein_id="WP_023552484.1"
                     /sec_met_domain="p450 (E-value: 5.8e-23, bitscore: 80.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPLFQQITDFANRANPYPLYEELRKNPVLHEEEGGPYVLSSY
                     WDIEALLHDPRISSDAANLAAAGDDELSGPEATGLPPSFIRLDPPEHDRLRRIANSSFG
                     PPHRPRRIENMRGELGEIVTGLIDGFGDARQIDLVDQFAYPFPVTVICRLLGVPREDEP
                     RFRAWVDPIVAGLDPDARTSAESQRTAQEARLQLGMYLNGLVDQRAREPRDDMLSDLVN
                     SHGPDGAMTTMEVLSTAVLLLIAGHETTVNLITNGMLTLLRHPEFLERLRNDPGLSVKI
                     VEELLRYEPPVQIVPQRTCIADIEVRGVTIPKGSRIWLMLAAGNRDPERFQDPERFDPD
                     REDIQHLGFGSGIHSCFGAPLARLETQIALSELARRLENPRLVADPPPYRQNAVLRGPR
                     HLEIAFDGVRQAV"
     gene            complement(6744..8135)
                     /locus_tag="M878_RS85260"
                     /old_locus_tag="M878_38500"
     CDS             complement(6744..8135)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671327.1"
                     /locus_tag="M878_RS85260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38500"
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="WP_023552486.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.2e-43, bitscore:
                     147.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPADYVDWLRREGRIVIVGASLAGLRAAETLRAEGFAGELTLIGD
                     EPYEPYDRPPLSKSVLLGKASPHRTELPHRREIDAKWRLGVAATGLDLSAKRVKLADGD
                     EVEYDRLLIATGVRARPWLKADEGRLDGVCLLRTRDDAADLYQRLKAGPRRVFVIGAGF
                     AGSEVASACRETGIPVTVAERAGAPLVGALGGVIGAVAADLQTENGVDLRTHVTVTSLE
                     GDSVGRVRAVHLSDESVVEADVVVVSLGSVRNTDWLTGSGLGAGPRGIACDAGCRAFDF
                     RGIVTDDVFVAGDVARSPHALFGYQFLSLEHWGNAVAQAETAAHNMICHGADRRPHLWM
                     PAFWSSMFGVNIKSVGVPPMGDQLMITQGALAERRFVGVYGYQGRVIAAVSFDNARWLE
                     FYARQIERGAPFPVEFPTMDRRPEGRQPVAADFPDPSLPTHGPTVTLTGYSPADQQLVF
                     HPARH"
     gene            complement(8125..8370)
                     /locus_tag="M878_RS85265"
                     /old_locus_tag="M878_38505"
     CDS             complement(8125..8370)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546701.1"
                     /locus_tag="M878_RS85265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38505"
                     /product="ferredoxin"
                     /protein_id="WP_023552488.1"
                     /transl_table=11
                     /translation="MRLVVDLNKCQGYAQCAFLAPDVFAMHGEESLVYNPHAPEEQRER
                     LARAVAACPVQAITADGLDGAGEQSTGSAQEARDAR"
     gene            complement(8556..9227)
                     /locus_tag="M878_RS85270"
                     /old_locus_tag="M878_38510"
     CDS             complement(8556..9227)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236297.1"
                     /locus_tag="M878_RS85270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38510"
                     /product="hypothetical protein"
                     /protein_id="WP_023552490.1"
                     /transl_table=11
                     /translation="MQQQAQRVLETPRAAGLAGVVFALLLAAAIVLMRLGIPEGAESVT
                     AQGFTDSGRRGAVRAALALVPFAGVFFLWFVGAVRAHIGAGEDKFLATVFLGSGLVFTA
                     TLFGAAAAAGAVLAVTHPAGATPALSSWDFGRHFAYTLMTEYATRMAAVFACSMSVIGH
                     RLGILPRRLSVLGLLTALTLLFAASEVPWAELVFPAWSLLLSVHIIRATGGARSRTAAN
                     P"
     gene            complement(9363..10004)
                     /locus_tag="M878_RS49700"
                     /old_locus_tag="M878_38515"
     CDS             complement(9363..10004)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="M878_RS49700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38515"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_158692826.1"
                     /transl_table=11
                     /translation="MISPEGADMARLFDSLGMEYEHAFADRKQAQIDAVEELSRRLARG
                     SRVLDVGCATGRPTTEQLCAKGLDVTGVDVSEVMLAHARRQVPQARFVLADLYCDDADL
                     GVYDAVVCLFCLVNLPEPRFVEGLRRLAARTVPGGTVLVAVPESQGTQDVRFLDLTYRP
                     LRCLREDVRRYARLAGLEVDRVETRAESATDGGASSGRSLFLWARTPPSG"
     gene            complement(10001..11959)
                     /locus_tag="M878_RS95285"
                     /old_locus_tag="M878_38520"
     CDS             complement(10001..11959)
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="M878_RS95285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38520"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_023552494.1"
                     /sec_met_domain="CDPS (E-value: 8.4e-80, bitscore: 266.5,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 1.4e-17, bitscore: 62.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHSEPQVLEDHRVRVLPFGASSERILQRGDHALFGVSTGNSYFS
                     RRNLANAMAWAVERFAAVDVVHADIALEAMLEALGYERVAARKSVAKQLRGVRRRIDGA
                     LEDIGAAAERVRARPLSAFLDHPSYREVRARTRAALRTDVELRSVRDAMAYQFLAKRLK
                     PDDLPTPAQVEAALAYVDAELPFFVDTPRILGVASSVHCYHTVLALGRLLFGERRMALR
                     PADNQGYAIVACRDSGKQIAMASTSTEAPAPVPPYAGVEWPLSRRGDVVPAECARLRAE
                     SPVARIRTLTGDDAWLVTSYELARQVLEDERFSLRETAAPDVPRQYALTIPPEVVNTMG
                     NVNSAGLHQEVLRAFGPRSGPASAEWMAARAHELVDAMVEEGPPVDLRQRFAEPYSAAL
                     VCEVLGLPYEDGLRLMSGLDLGFVTSPVVYDGCTANWDKDYAFVLRHVRDDRAAQRGLI
                     RRLCELRDDPERDGGDLTDEMLAATVTSLFGAGAMSTYVFLLHAVLTLIRHPEAMDRLR
                     ERPEAMPRAVEELLRCTLSIGDGLPRIARADVQVGEVLVRAGELVLVCVEGANFDPEQF
                     PDAERFDLDRSPNAHLSFGAGSHFCPASTISRVHAAEALTVLLARLPRLRLALPVDQLV
                     WRTGNIKRVPERLPVLW"
     misc_feature    complement(11522..11524)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12007..12020)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    12012..12025
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.62"
                     /tool="antismash"
     misc_feature    12028..12044
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            12221..13063
                     /locus_tag="M878_RS85275"
                     /old_locus_tag="M878_38525"
     CDS             12221..13063
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671324.1"
                     /locus_tag="M878_RS85275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38525"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_031226780.1"
                     /transl_table=11
                     /translation="MASPVRSVPEDLRRDPLPLRGRTALVTGASRRAGIGHAVARRLAA
                     YGASVYLHHHVAHDQAMPWGADSIEAVVGSVREVAGDPGARVVAGPGDLADAAEPVRLI
                     DAVVGEFGRLDILVANHALSGSDGTLDEIDAAMLDAHWAVDTRSVLLLVQAYARARAAP
                     PDGVPGGRVVLMTSGQDIAGGMPGEIAYALQKGALASITRSLAGALAEHGITVNAVNPG
                     PVDTGYATGEVHAAVAERFPGGRWGLPDDPARLVAWLATDEAGWITGEVINSEGGFRR"
     gene            complement(13130..14821)
                     /locus_tag="M878_RS85280"
                     /old_locus_tag="M878_38530"
     CDS             complement(13130..14821)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327560.1"
                     /locus_tag="M878_RS85280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38530"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_023552497.1"
                     /transl_table=11
                     /translation="MPETKSPLPRQVADAYVDDLIALDPVTGTYLGVKESSSRLPDYSP
                     TGQAALAELARATLAKLDEAERQPGADSDVERRCGRLLRERLTAELAVYDADEHLRAVG
                     NMSTPGHSVRDIFTVTPAQTDEDWAAIAERLRAVPGALAGYRASLQLGLDRKLFAAPRP
                     TATYIQQLTEWTDTDGQGRGWYEDFAAAGPEALRAELDEAAGAATGALVELRDWLRDVY
                     APAIEGAPNTVGRERYARWSRYFNGTDLDLDEAYAYGWAEFHRILGEMKLEAEKILPGA
                     ETPWVALAHLDEHGRHIEGVEEVREWLQGLMDKAIEDLDGTHFELAERVRKVESCIAPP
                     GGAAAPYYTAPSEDFSRPGRTWLPTMGQTRFPVYDLVSTWYHEGVPGHHLQLAQWAHVA
                     EDLSRYQATIGGVSANAEGWALYAERLMDELGYLTNPEERLGYLDAQMMRAARVIVDIG
                     MHLELEIPADSPFHPGERWTPELAQEFFGSHSSRPADFVESELTRYLTIPGQAIGYKLG
                     ERAWLLGRENARKRHGDDFDLKAWHMAALSQGSLGLDDLVDELSQL"
     gene            complement(14875..15360)
                     /locus_tag="M878_RS85285"
                     /old_locus_tag="M878_38535"
     CDS             complement(14875..15360)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671322.1"
                     /locus_tag="M878_RS85285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38535"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_023552499.1"
                     /transl_table=11
                     /translation="MAESVALDPVDLHLLRLLQNDARITYRDLAEQVGVAPSTCLDRVT
                     RLRRSGVILGHQLRLDPAKLGRGLQALLLVQVRPHRRELVGPFVERIRALPEARTVFHL
                     TGPDDYLVHVAVADMADLQRLVLDEFTAQREVARVETRLIFQQWECGPLLPPGHAQS"
     misc_feature    15345..15359
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            15421..16620
                     /locus_tag="M878_RS85290"
                     /old_locus_tag="M878_38540"
     CDS             15421..16620
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671321.1"
                     /locus_tag="M878_RS85290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38540"
                     /product="PLP-dependent transferase"
                     /protein_id="WP_023552500.1"
                     /transl_table=11
                     /translation="MDTATTGAYDGVRTATRALATEAVHAGRDDLARQGLHAPPIDLST
                     TYPSYDSRAEAARIDAFATDGADPVGPPVYGRLGNPTVARFETALARLEGTESAVAFAS
                     GMAALSAVLLARAATGLRHVVAVRPLYGCSDHLLTAGLLGTEVTWTDPAGIADAVRPDT
                     GLVMVESPANPTLAELDLRAIAHACGAVPLLADNTFATPVLQRPAEHGARMVLHSATKY
                     LGGHGDALAGVVACDEEFAGRLRQIRFATGGVLHPLAGYLLLRGLSTLPVRVRAASANA
                     AELVRRLAADPRVARVHYPRLGGAMIAFEVYGDPHEVISQVRLVTPAVSLGSVDTLIQH
                     PASISHRIVDADDRRGAGVSDRLLRLSVGLEDVDDLWADLDQALGERARRPVPLQEAVR
                     "
     gene            complement(16768..18213)
                     /locus_tag="M878_RS85295"
                     /old_locus_tag="M878_38545"
     CDS             complement(16768..18213)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988458.1"
                     /locus_tag="M878_RS85295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38545"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_245238271.1"
                     /transl_table=11
                     /translation="MSADMSDVTRAKHGRPVHHWRRDLVELAALFTAVAVADGVANLIG
                     HGPDGPALLVISALVLAATAGFHTWWARRHGHAPPTEDTGARPSAETRSAGPSEQPGEP
                     ADDVAAAGALWRMRTTVKDEPGSLAALCTALAERRVDILSLQTHPLADGTVDEFLLRAP
                     GALAAAEISRVVSLAGGTSTWIERADAHDLVDAPTRVLGLAARTALDAAELPLALRQLL
                     GRCTIRSLPGTPVGGDRGPQPVPVEGVLEDTVMRLRAPEGGVLTVERPYLPFTPTEFAR
                     ARALVELDNRLGPRIPRGKDVLTLPEGNDITVRRVDTSDVAAAKAMHERCSPRTLGLRY
                     HGPVSDADRYLNHLLSPRFGRTLAAQTASGRIVGLGHLLWDGDETEVALLIEDDWQQRG
                     IGGELLGRLVALAVEARCESVYAVTQASNTGMVAAMRGLGLPLDYQIEEGTLVITARLD
                     VVPAASRPQHDTRHQLGDPARRD"
     gene            complement(18485..19996)
                     /locus_tag="M878_RS85300"
                     /old_locus_tag="M878_38550"
     CDS             complement(18485..19996)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571131.1"
                     /locus_tag="M878_RS85300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38550"
                     /product="alkaline phosphatase D family protein"
                     /protein_id="WP_078630687.1"
                     /transl_table=11
                     /translation="MPGGLGAAPAFARSGRPQAGWGVQAGDVTTDSGLVWVRSDRPARM
                     IVETAATESFRNPRRWHGPLLGAGTDFTGTTRLHGLASGEQIHYRVLLADPDDPRRTGE
                     PVTGTFRTAPVKRRRDVRFVWSGDLAGQGWGINESIGGYRIFDAMAKADPDFFLCSGDN
                     IYADGPIAATASLPDGSVYRNVTTEEKSHVAVTLDDYRGNFRYNLLDSALRRFNAQVPN
                     IIQWDDHEVRNNWYPGEVIGTGTPYPAGTRLDDLAPRSRQAFSEYFPISTISGRPDGRI
                     YRVINHGPLLDVFVLDMRTYRNANSPDNQTADPVGILGREQLEWLKRELAKSRAVWKVI
                     ANDMPLGLVVPDPVEGKPDFEAVAQGDPGAPLGRELQIAELLRFIKHRRITGTVWLTAD
                     VHHTSAQHYDPSRAAFKDFEPFWEFVSGPLNAGAFPANALDGTFGPDRVFVKAPTTANV
                     SPAEGYQFFGEVDIDGESGEMTVRLREYDGTVLFTQTLQPGRVGR"
     assembly_gap    20002..20421
                     /estimated_length=420
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            complement(20715..21548)
                     /locus_tag="M878_RS85305"
                     /old_locus_tag="M878_38555"
     CDS             complement(20715..21548)
                     /NRPS_PKS="Domain: Abhydrolase_1 (29-260). E-value:
                     7.2e-27. Score: 86.5. Matches aSDomain:
                     nrpspksdomains_M878_RS85305_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827243.1"
                     /locus_tag="M878_RS85305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_38555"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_023552510.1"
                     /sec_met_domain="PF00561 (E-value: 3.7e-20, bitscore: 71.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.2e-22, bitscore:
                     78.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATVSFKVPTPHGPKDVTVSYARVGRGEPLVLLHGIGHHRQAWD
                     PVVDILATERDVIAVDLPGFGASPGLPDGLAYDLPTTNSVLGALFEALVLDRPHIAGNS
                     LGGLLALELGREKLVRSVTALSPAGFWTDAERRYAFAVLLAMRGIAQRLPLPLVERLSR
                     TAAGRTALTSTIYARPARRAPEAVVAETLALAGATGFDATLRAGTSVRFTDDLTGLPVT
                     VAWGAQDRLLVRRQGVRAKQLIPHARLVRLPGCGHCPMNDDPALVARVILDGSSR"
     aSDomain        complement(20769..21461)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS85305_Abhydrolase_1.1"
                     /evalue="7.20E-27"
                     /label="M878_RS85305_Abhydrolase_1.1"
                     /locus_tag="M878_RS85305"
                     /protein_end="260"
                     /protein_start="29"
                     /score="86.5"
                     /tool="antismash"
                     /translation="PLVLLHGIGHHRQAWDPVVDILATERDVIAVDLPGFGASPGLPDG
                     LAYDLPTTNSVLGALFEALVLDRPHIAGNSLGGLLALELGREKLVRSVTALSPAGFWTD
                     AERRYAFAVLLAMRGIAQRLPLPLVERLSRTAAGRTALTSTIYARPARRAPEAVVAETL
                     ALAGATGFDATLRAGTSVRFTDDLTGLPVTVAWGAQDRLLVRRQGVRAKQLIPHARLVR
                     LPGCGHCPM"
     CDS_motif       complement(21204..21254)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS85305_0001"
                     /evalue="1.10E-03"
                     /label="NRPS-te1"
                     /locus_tag="M878_RS85305"
                     /protein_end="115"
                     /protein_start="98"
                     /score="11.6"
                     /tool="antismash"
                     /translation="HIAGNSLGGLLALELGR"
ORIGIN
        1 gccgaacgcg tcgactgccc ggtgccccgc ccgctggccc gcatcaaggg cacgctggac
       61 ggcctcctcg ccgatcccgg cctcgcccgg cacgaggacg cctgggtcga agccaccctc
      121 accgacccgg tccgccccgc cgaccccatg gcccggctca ccgagcgctt cccgcacacc
      181 ctcagcctcg tcttcgcccc cgagcgcgcc ccggacgacc cctcggtgtc gtacgcccgg
      241 cgcctcgccg gccgcagcga ccagcagatc gcccaggact tcgtcgccca tgtgcgcggc
      301 gccgggcccg acgagcgcga gacggccgtc ctgcgcgagg ccttcgacgc cgtgcgcgcc
      361 gacgccgtcg tacgggaggt ggcccgatga ggctgcaccg gcttgacatc accgccttcg
      421 ggcccttcgg cggctcccgc ggcgtcgact tcgacgccct gtccgccgcc gggctcttcc
      481 tgctgcacgg ccccaccggc gccggaaaga cctccgtcct ggacgccgtc tgctacgccc
      541 tgtacggctc cgtccccggc gcccggcaga gcggccaggg tatgcacctg cgcagcgacc
      601 acgccgagcc gcgcacccgc accgaggtcc gcctcgacct caccgtcgcc ggacgccggc
      661 tggagatcac ccggcagccg ccgtgggagc ggcccaaact gcgcggcacg ggcacgaccg
      721 tcgacaaggc ccagacctgg ctgcgggagt acgatgccac ggccggcgcc tggaaggacc
      781 tcagccgctc ccaccaggag atcggcgagg agatcaccca gctcctcggc atgagccgcg
      841 agcagttctg ccaggtcgtg ctgctgcccc agggcgactt cgcccgcttc ctgcgcgccg
      901 acgccgaggc ccgcggcaag ctgctgggcc gcctcttcga cacccagcgg ttcgccgacg
      961 ccgagaagcg cctcgccgag cgccgccggg ccaccgaggc acgcgtacgg gaaggcgacg
     1021 cggcgctgct cgccgacgcc caccgcatgc agcaggaagc cggcgacgcc atggaactgc
     1081 ccgagctggc gcccggcgat cccggtctgg ccgacgccgt cctcggcgcc gccgccctcg
     1141 cccgcgccac cgcccgcgag cgcctcacca tcgcccactg ccgcctggcc gccgccgagt
     1201 ccgcgcacac cgagatccgg cgcgccctgg acgatgtacg cgaactcgcc cggctgcaga
     1261 gccggttcac cgaggcccgg cagcgcgccg agcagctcca ggagcgggcc ggcgcccacc
     1321 acgaggcgca gcggcgcatg gagcggtccc gcaaggcgga ggcggtcgcg cccgcgctgg
     1381 agctgcgcga ggccgccgaa gaggagcacc gcagggccac cacggccgag gcgagcgtgc
     1441 gcgggacgct ccccggctcc tatgccgacg ccggcgcgag cggactggcc gcagccgccc
     1501 gccgggccgc cgaggaactg ggcggtctgg acgcggcccg gcgcgccgag cagaagctcg
     1561 tccggctggc cgaggagcgg tccgggctcg accgccagga gcgcgccgac gaggaggtgc
     1621 tgcgcgaggc cgacgcctgg ctcgacgcgt gggacgccac gcgcgcggcc ctgcagtccc
     1681 gcgtcgactc cgcccaggag gccgccaccc gcgccgagca gctcgccgtc cagcgggacc
     1741 cgatgcgcgg gcggctcacc gcggcccgca cccgggacac gctggccgcg gacctggagg
     1801 acgcacagcg ccgggcgctg gcctccgagc agcaggcgct cggctcccgc gcccactggc
     1861 tcgacctcaa ggaacagcgt ctgaacggca ttgccgccga gctggccgcc cacctcaccg
     1921 acggcgagcc ctgcgccgtc tgcggagcca ccgaacaccc cgcaccggcc cgcaaggtcg
     1981 ccgggcacgt cgaccgtgag gccgaggaga gggcccacaa ggcctcccag caggccgacc
     2041 ggcagcacac cgaggaccag cggcggctcg gcgtcgtccg cgaggccctg gccgccgcca
     2101 ccgccgaagc cggcgacacg cccaccgcgc aactcgaaga gacggccgcc gagttggagc
     2161 aggagtacgc ccgcacccgt cgcgacgcct ccgtcctgca cgccgcccac gaagagctgc
     2221 ggcgcgccga gcgggagcgc gagcagcgcc tcgccgaccg tcagcaggcc gccgtgcggg
     2281 ccgcgtcccg gggtcacccg acgcgagacc ctggagcagg aacagggccg gctggaggag
     2341 gagttgagca gggcacgcgg cggctcgggc agcgtggccg cgcgtgccgc gcagctggag
     2401 cggcaggtgg cgctgctcac cgacgccgcc gacgccgcgc gcaccgccga ggacaccgcg
     2461 cagcgcctga nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3301 nnnnnnnnnn ctccgcgagg agtacgaccg ggtcgcccgc ctcgccgccc tcaccgcggg
     3361 cacctccgcc gacaacgaac gcaagatgcg cctggagtcg tatgtgctcg cggcccggct
     3421 ggagcaggtc gccgccgccg cgaccgcccg gctgcagcgc atgtcggcgg gccgctacac
     3481 gctcgtccac tccgacgacc gcaccggacg cggccgcagc ggcctcgggc tgcacgtggt
     3541 cgacgcctgg accggacgcg aacgcgacac cgccaccctg tccggcggcg agaccttctt
     3601 cgcctccctc gcgctcgccc tcggcctcgc ggacgtcgtc accgacgagg ccggcggcgt
     3661 ccgcctcgac acgttgttca tcgacgaggg cttcggcagc ctcgacgacc agaccctcga
     3721 cgaggtcctc gacgtcctcg actccctgcg cgagcgcgac cgcagcgtcg gcatcgtcag
     3781 ccacgtcccc gacctgcgcc gccggatcca cgcccagctg gaggtcgtca agggcagagc
     3841 gggctcgacg ctgcggcagc ggggcgtctg acgggtcagc ggcccagcgc gcgccggggc
     3901 aggggagagg agtacacgac gctggtggtc acggagccca gcgcgccgat cctcccggag
     3961 atctcctcca gatgcgccat ggaccgcgcg gcgaccttga tgacgaagca gtcgtcgccc
     4021 gtcacatggt gcgcctccag gatctcgggc gtcgcggcca ccaggtcgtg gaacggcttg
     4081 tagttgccgt tcggataccg cagccgtacg aacgccagga tcggcagccc gagccgctcg
     4141 gggtcgacga ccgccgcgta cccctggatc acgccggcct cctccagccg ccggacccgc
     4201 tcggtgacgg cgctcggtga catggagacg gcgcgcgcca gctctgcgta gctggcccgg
     4261 ccctcccgct ggaggacttc cagaatgcgc cagtcggtag cgtccgggga atacacggtc
     4321 atcccggatg gatagcaggg aattcccggc tcgggcaagg acgacaccgt ggattctcac
     4381 ttcagggagc cgaccgcgag ccgtagattt ccagtcatga tcaccaagac cacccagacc
     4441 tctgtgaatc ccgtcctgcg ggtcgccccc gccgctcccg ccgaggccgc cgcctacttc
     4501 cgggcgagcc tggccttcca cgccgacgtc tccgacgtgg ccgccgcgct cgcggccggc
     4561 ggcgaccccg gcttcgccgt cgtcgacaca cgctcgaccg agtcctggga ccagggccac
     4621 atcccgggcg ccgtccacct gcccaccgcg ctcgtccccg ggcaggccga gcagctcctg
     4681 gacaagtccg tgccggtggt gacgtactgc tggggccccg gctgcaacgg cgccacccgc
     4741 gccgcactcg cccttgccga actcggctac caggtcaagg agatgctcgg cggcttcgag
     4801 tactgggccc gcgagggctt cgcctacgag acctggcagg gccccggccg ccgcgacgcc
     4861 gacccgctga ccgcgctcgt cgaaggcgag tgcggctgct gacgaacgcc gtgtaggttc
     4921 tctgcccatg gctcgatacg cggatccagg cgcgctggag tgggtggaat cgggcggcgg
     4981 cccgctgata gccgtcccgg agacggtgct gccgttctgg gcgggcgccg acagcgagga
     5041 cctcgacacc gactacgacc gggcgtgcga ggtcgacggg tacgtcggcc tgctgcccgt
     5101 cggcgacagc gcggccctgg tgttcggcga cgaacccgcc tccacctcgt tcctgccgga
     5161 ccacgccacc ttcgtacggt ggtccgccgc gaactccgag gcggaactgc tcgccaccgt
     5221 ccctgccgcc ctcgaggcgg cggtgtgggg gagcgaggtg cactggcggg tgcccggccc
     5281 ggtgctgctg ttcgactcgg cctggcccgg ccaggccgcc gaccgcaccg aacacctccg
     5341 ggtgtcgctg gaggcgggca catacgcggt gcgggccgcg tatgtgcagc cggggccgga
     5401 gacctgggtc gggctggtac ggctcacccg gctcgcgcac tgacccggcg cgtcttccga
     5461 cgtcacacgg cctgacgcac tccgtcgaag gcgatctcca ggtgccgggg gccgcgcagc
     5521 accgcgttct gccggtacgg tggcggatcc gccaccaggc ggggattctc cagccgccgg
     5581 gccagctcgg acagcgcgat ctgggtctcc agccgggcca gcggagcgcc gaagcagctg
     5641 tggatgccgc tgccgaaacc gaggtgctgg atgtcctcgc gatccgggtc gaagcgctcg
     5701 gggtcctgga aacgctcggg gtcgcggttg cccgcggcca gcatcagcca gatacgcgag
     5761 cccttgggga tggtcacccc gcgtacctcg atgtcggcga tacacgtgcg ctgcggcacg
     5821 atctgcaccg gcggctcgta gcgcagcagc tcctccacga tcttcaccga caggccagga
     5881 tcgttgcgca gccgctccag gaactccgga tggcgcagca gcgtgagcat gccgttggtg
     5941 atgaggttga cggtcgtctc atggcccgcg atgaggagca gcaccgccgt gctgagtacc
     6001 tccatcgtcg tcatggcgcc gtccggaccg tgactgttca ccaggtcgga gagcatgtcg
     6061 tcgcgaggtt ccctggcgcg ctggtccacc aacccgttca ggtacatgcc gagctgcaac
     6121 cgtgcctcct gcgcggttcg ctgggattcg gcgctcgtac gggcgtcggg gtccagaccg
     6181 gcgacgatcg ggtcgaccca ggcacggaag cggggctcgt cctcacgcgg tacgccgagc
     6241 agccggcaga tcacggtcac cgggaagggg tacgcgaact ggtcgaccag gtcgatctgc
     6301 cgcgcgtccc cgaagccgtc gatcagcccg gtgacgatct cccccagctc gccccgcatg
     6361 ttctcgatcc ggcgcggcct gtgcggcggc ccgaaggagc tgttggcgat cctccgcagc
     6421 cggtcgtgct ccggcgggtc gagccggatg aagctcggag gcagccccgt cgcctccggc
     6481 ccggacagct cgtcgtcccc ggcggcggcc agattggcgg cgtcggagct gatccgcgga
     6541 tcgtgcagca gcgcctcgat gtcccagtac gagctgagga cgtacgggcc gccctcctcc
     6601 tcgtgcagga ccggattctt gcgcaactcc tcgtacagcg ggtacgggtt ggcacggttg
     6661 gcgaagtcgg tgatctgctg gaacagcggg gcttgcgtca tgacaggtcc tcggggcgtc
     6721 ggggcgtcgg ggccgggcgg cgatcagtgc cgcgccgggt ggaagaccag ctgttggtcg
     6781 gccggtgagt aaccggtgag ggtcacggtc gggccgtggg tcggcaggga cgggtcgggg
     6841 aagtccgctg ctaccggctg ccggccctcg ggacgccggt ccatcgtcgg gaactccacc
     6901 gggaacggcg cgccccgttc gatctgccgc gcgtagaact ccagccaccg ggcgttgtcg
     6961 aagctcacgg cggcgatgac gcgtccctgg tagccgtaca cgccgacgaa ccggcgttcg
     7021 gccagtgcac cctgcgtgat catgagctgg tcacccatgg gcggcacccc gaccgacttg
     7081 atgttcacac cgaacatcga cgaccagaag gcgggcatcc acagatgcgg gcgccggtcg
     7141 gcgccgtggc agatcatgtt gtgcgcggcc gtctccgcct gggcgacggc gttgccccag
     7201 tgctccagcg agaggaactg atagccgaac agcgcgtgcg gggagcgcgc gacatcgccc
     7261 gcgacgaaca cgtcgtcggt gacgatgccc cggaagtcga aggcacggca gcccgcgtca
     7321 caggcgatgc cccgaggccc ggcacccagc cccgacccgg tcagccagtc ggtgttgcgc
     7381 accgagccca gcgagaccac gaccacgtcc gcttcgacga cactctcgtc ggacagatgg
     7441 acggcacgca ccctgccgac cgagtcgccc tccagcgagg tcacggtgac atgggtgcgc
     7501 agatccacgc cgttctcggt ctgcagatcg gcggcgaccg cgccgatcac gccgccgagc
     7561 gcgcccacca gcggcgcacc cgcacgctcc gccacggtca cggggatgcc cgtctcccgg
     7621 catgccgagg cgacctccga accggcgaac ccggcgccga tcacgaacac ccggcgcggc
     7681 cccgccttca accgctggta cagatcggcc gcgtcgtccc gtgtgcgcag caggcagacg
     7741 ccgtccagcc ggccctcgtc cgccttcagc cagggccggg cgcgcacccc ggtcgcgatg
     7801 agcagccggt cgtactccac ctcgtccccg tcggccagct tgacccgttt ggccgacaga
     7861 tccagaccgg tcgccgcgac gccgagccgc cacttggcgt cgatctcccg gcggtgcggc
     7921 agctcggtcc ggtgcgggga cgccttgccc agcaggaccg acttggacag cggcggccgg
     7981 tcgtacggct cgtacggctc gtcaccgatc agggtcagct caccggcgaa accctccgca
     8041 cgcaaggtct cggcggcccg cagtcccgcc agcgaggcgc cgacgatcac gatccggccc
     8101 tcgcgcctga gccagtcgac atagtcagcg ggcatcgcgc gcctcctggg cggagccggt
     8161 gctctgctca cccgcgccgt ccaggccgtc cgccgtgatc gcctgcaccg ggcaggccgc
     8221 gacggctcgg gccagccgtt cgcgctgttc ctcgggtgcg tgcgggttgt agaccagtga
     8281 ctcctcgccg tgcatggcga agacgtcggg agcgaggaac gcgcactggg cgtacccctg
     8341 acacttgttg agatcgacga cgagccgcat cgacgctccg cccttccggt ggcaggtccg
     8401 gcgcgcaccg gtctttcgca cggcacgccc ggacggcggt catgtcccgt ttgccagcat
     8461 gagcgcgacg gagcaacatc gcccgtcggg aaacccccgt tcgggccgca agtcggccgg
     8521 tgcacgggcg cgcgggcgct acggcgatgc gtccgtcacg ggttcgccgc ggtgcgggac
     8581 cgggcgcctc cggtcgcccg gatgatgtgg acactcagca gcagcgacca ggcggggaag
     8641 accagctccg cccagggcac ctcggacgcg gcgaagagca gcgtgagggc ggtcagcagc
     8701 cccaggaccg acagccggcg aggcaggatg ccgaggcggt ggccgatcac cgacatggag
     8761 caggcgaaga cggccgccat ccgcgtggcg tactccgtca tcagcgtgta cgcgaaatgc
     8821 cggccgaagt cccaggagga cagtgcgggc gtcgcaccgg cgggatgggt gaccgcgagg
     8881 acggcaccgg cggccgcggc ggcgccgaac agggtggcgg tgaagacgag tccgctgccg
     8941 aggaagacgg tggccaggaa cttgtcctcg ccggcaccga tgtgcgcccg caccgcgccg
     9001 acgaaccaca ggaagaagac gccggcgaac ggcacaagcg cgagggcggc acgcaccgcg
     9061 ccacggcgcc cggaatcggt gaacccctga gcggtgaccg actccgcccc ctcgggaatg
     9121 cccagccgca tcaggacgat cgccgccgcc agcaacagcg cgaacacgac tcccgccagc
     9181 ccggcggccc tcggcgtctc cagcacccgc tgcgcctgct gctgcatgcc accccgcctc
     9241 ctccacatcg cctcggccac cagctagccg ccgcctggcc ggttacgcca ccgggggacg
     9301 gccgtaaggc cgagcgaccg gtggcacggc cacggggcga cgtgagtccc cgggctccgg
     9361 actcacccgg acggcggggt cctggcccac aggaacagac tcctcccgga ggacgccccg
     9421 ccgtccgtcg cggattcagc gcgggtttcc acccgatcga cctccagccc ggccagccgg
     9481 gcgtatcggc ggacgtcctc gcgcaggcag cgcaggggac ggtacgtcag gtcgaggaac
     9541 cgcacgtcct gggtgccctg ggactccggc accgcgacca gaacggtgcc gcccggcacg
     9601 gtgcgggccg cgagccgtcg cagaccttcc acgaagcggg gttcgggcag gttgacgagg
     9661 cagaacagac acaccacggc gtcgtacacg ccgaggtcgg cgtcgtcgca gtagaggtcg
     9721 gccaggacga aacgcgcctg gggcacctgg cgtcgcgcat gggccagcat gacctcggag
     9781 acgtcgacgc ccgtgacgtc cagccccttg gcgcacagct gctccgtggt gggacgaccc
     9841 gtcgcgcacc ccacgtccag gacccgggag ccgcgggcga ggcggcgcga cagctcctcg
     9901 acggcgtcga tctgggcctg cttccggtcg gcgaaggcgt gctcgtactc catgccgaga
     9961 ctgtcgaaga ggcgcgccat gtcggcgcct tccggtgaga tcaccacagg accggaagcc
    10021 tctcggggac ccgcttgatg ttgcccgtgc gccagaccaa ctggtcgacg ggcagcgcga
    10081 gacgcagccg cgggaggcgt gcgaggagga cggtgagggc ttccgcggca tggacacggg
    10141 agatcgtcga cgcagggcag aagtggcttc ccgccccgaa cgacaggtgc gcgttgggcg
    10201 agcggtcgag gtcgaaccgc tcggcgtccg ggaactgttc ggggtcgaag ttcgcgcctt
    10261 ccacgcagac cagcaccagc tctccggctc gcaccaggac ctcgccgacc tgaacgtcgg
    10321 cgcgggcgat ccggggcagt ccgtcgccga tcgacagcgt gcaccgcagc agctcctcca
    10381 cggcgcgtgg catcgcctcg ggccgctcac gcagtcggtc catggcctcc gggtgccgga
    10441 tcagtgtcag tacggcgtgc agcaggaaca cataggtgct catggcgccg gcaccgaaga
    10501 gcgacgtgac cgtggcggcg agcatttcgt ccgtcaggtc tccgccgtcg cgctccgggt
    10561 cgtcgcgcag ctcgcacagc cgccggatca ggccccgctg ggcggcacgg tcgtcgcgca
    10621 cgtgccgcag tacgaaggcg tagtccttgt cccagttggc ggtgcagccg tcgtacacga
    10681 cggggctggt gacgaagccg aggtccaggc cggacatcag ccgcagtccg tcctcgtacg
    10741 gcagaccgag tacctcgcag accagggcgg cggagtacgg ttcggcgaac cgctgccgca
    10801 gatcgaccgg tggcccctcc tcgaccatgg cgtcaaccag ttcgtgcgcc cgcgcggcca
    10861 tccactccgc ggacgccggc ccggaccggg gcccgaaggc gcgcagcacc tcctggtgga
    10921 gcccggcact gttgacgttg cccatggtgt tgacgacctc cgggggaatc gtcagggcgt
    10981 actggcgcgg tacatcggga gccgccgttt cgcgcaggct gaagcgttcg tcttccagga
    11041 cctgccgggc cagctcgtag ctggtgacca gccaggcgtc gtcgccggtg agggtccgga
    11101 tccgcgcgac ggggctctcc gcgcgcagcc gggcgcactc ggcgggcacg acgtcgccgc
    11161 gccgcgacag cggccactcg acaccggcgt aagggggcac gggggcgggg gcttcggtgg
    11221 aggtggatgc catggcaatc tgctttcctg agtcgcggca cgcaacgatg gcgtagccct
    11281 ggttgtcggc cgggcgcagc gccatccggc gctctccgaa cagcagtcgg cccagcgcga
    11341 ggacggtgtg gtagcagtgg acggacgagg cgacacccag gatgcggggg gtgtcgacga
    11401 agaacggcaa ctcggcgtcg acgtacgcga gcgccgcctc cacctgagcg ggggtgggca
    11461 ggtcgtccgg cttcagccgc ttggcgagga actggtacgc catggcgtcc cggaccgacc
    11521 gtaactccac gtcggtgcgc agagccgccc gtgtccgcgc ccgcacctcc cggtaggagg
    11581 ggtggtcgag gaacgcggac agcggccgcg cccttacgcg ttctgcggct gcgccgatgt
    11641 cttcgagagc gccgtcgatg cgccgccgca cgccgcgcag ttgcttggcc acgctcttgc
    11701 gcgcggcgac acgctcatag ccgagggctt cgagcatcgc ctccaaggcg atgtcggcgt
    11761 gtaccacgtc cacggcggcg aagcgctcca ccgcccacgc catcgcattg gccagatttc
    11821 tgcggctgaa gtaactgttg cccgtgctca ccccgaacag cgcgtgatcc ccacgctgca
    11881 ggatgcgttc gctgctcgcc ccgaacggga ggacccgcac tcgatgatct tccaggacct
    11941 gcggttcact gtgggccatc gtcactcccc tcgcatgcct atgtacgaat gcgcatcact
    12001 acatgcccac gtagagtgat cataatgtcg caaacacctc gaaagtgtga ctctgggtaa
    12061 tcatcgccga ggtcgcgcgc ccctcacgca ctccggctca tcccacggca ccgttcgcgc
    12121 gtgccgacat ccgtggccgc gccgggcggc aggcgggacc gcgccctcgc cccccaattc
    12181 gctcgcgcgg cgctccgcac gccccctagg gtgatccgcc atggcttccc ctgtgcgctc
    12241 cgttccggaa gacctgcgac gtgacccgct gcccctgcgc ggtcgtaccg ctctcgtgac
    12301 cggtgcgagt cggcgtgccg ggatcgggca tgccgtggcc aggcggctgg cggcgtacgg
    12361 ggcgagcgtg tatctgcatc accatgtggc gcacgaccag gccatgccgt ggggtgccga
    12421 cagcatcgag gcggtcgtcg gttctgtgcg tgaggtggcg ggggatcccg gggcgcgggt
    12481 cgtcgcgggc cccggggatc tggccgatgc ggccgaacct gtacggctga tcgacgccgt
    12541 cgtcggcgag ttcggccgac tggacattct cgtcgccaat cacgccctca gcggctcgga
    12601 cggcaccctg gacgagatcg acgccgcgat gctcgacgcg cactgggcgg tcgacacccg
    12661 ctccgtcctg ctgctggtgc aggcgtacgc ccgtgcgcgc gccgcaccgc ccgacggcgt
    12721 cccaggcggg cgtgtggtgc tgatgacctc cgggcaggac atcgcaggcg gtatgccggg
    12781 cgagatcgcc tatgcccttc agaagggcgc cctcgcctcg atcacccgat ccctggccgg
    12841 cgcgctcgcc gagcacggca tcacggtgaa cgcggtcaac cccggcccgg tggacaccgg
    12901 ttacgcgacc ggcgaggtcc acgcggctgt ggccgagcgg ttccccggcg ggcgctgggg
    12961 cctccccgac gatccggccc gcctcgtcgc ctggctggcg acggacgagg ccgggtggat
    13021 caccggggag gtcatcaact cggaaggcgg cttccggcgt tgaggcctgg gaccctctgg
    13081 gtcgtctgag ggtttctggg cccctcgggg cgccggggac gcctggccgt cagagctggg
    13141 acagttcgtc cacaaggtcg tccaggccca gcgagccctg ggacagggcc gccatgtgcc
    13201 aggccttcag gtcgaagtcg tcgccgtgtc gcttgcgggc gttctcgcgg cccagcagcc
    13261 aggcccgctc gccgagcttg tagccgatcg cctggcccgg aatcgtcagg taccgggtga
    13321 gctcgctctc cacgaagtcc gccggccggc tgctgtgcga gccgaagaac tcctgcgcca
    13381 gctccggcgt ccaccgttca ccggggtgga acggcgagtc ggcgggaatc tccagctcca
    13441 gatgcatgcc gatgtccacg atcacccgcg ccgcccgcat catctgcgcg tccagatagc
    13501 cgagccgctc ctcggggttc gtgaggtagc ccagctcgtc catcagccgc tccgcgtaca
    13561 gcgcccagcc ctcggcgttg gcgctgaccc cgccgatcgt cgcctggtag cgggagaggt
    13621 cctcggccac gtgcgcccac tgcgcgagct gcagatgatg cccgggcacg ccctcgtggt
    13681 accaggtcga gacgaggtcg tacaccggga accgcgtctg gcccatcgtc ggcagccagg
    13741 tgcggcccgg gcgggagaaa tcctccgacg gtgccgtgta gtagggggcc gcggcaccgc
    13801 cgggcggcgc gatgcacgac tccaccttcc gcacccgctc ggcgagttcg aagtgcgtgc
    13861 cgtccaggtc ctcgatggcc ttgtccatca ggccctgcag ccactcccgg acctcttcca
    13921 cgccctcgat gtgccggccg tgctcgtcga ggtgcgcgag cgccacccag ggggtctcgg
    13981 cgccgggcag gatcttctcc gcctccagct tcatctcgcc gaggatccgg tggaactccg
    14041 cccagccgta cgcgtacgcc tcgtccaggt ccagatcggt gccgttgaag tagcgggacc
    14101 agcgcgcgta ccgctcgcgg cccaccgtgt tcggggcacc ctcgatcgcc ggcgcgtaca
    14161 cgtccctaag ccagtcccgc agctccacca gcgcgccggt cgcagcgccg gccgcctcgt
    14221 ccagctctgc gcgcagcgcc tcgggacccg cggcggcgaa gtcctcgtac cagccgcggc
    14281 cctggccgtc tgtgtccgtc cactcggtga gctgctggat gtacgtcgcc gtcgggcgcg
    14341 gtgccgcgaa cagcttgcgg tccaggccca gttgcagcga tgcacggtag cccgcgagcg
    14401 cgcccggcac cgcgcgcagc cgctccgcga tcgccgccca gtcctcgtcc gtctgcgccg
    14461 gcgtgaccgt gaagatgtcc cgcaccgagt ggcccggcgt gctcatgttg ccgaccgcgc
    14521 gcaggtgctc gtccgcgtcg tacacggcga gttcggcggt cagccgctcc cgcagcagcc
    14581 gcccgcagcg ccgctccacg tcactgtccg cacccggctg ccgctccgcc tcgtccagct
    14641 tcgcgagggt ggcccgggcc agctccgcga gggccgcctg gcccgtgggc gaatagtcgg
    14701 gcagccggct cgaactctcc ttcacaccga ggtaggtacc ggtgaccggg tcgagggcga
    14761 tgaggtcgtc cacgtacgcg tcggcgacct gacggggcag cgggctcttc gtctcaggca
    14821 tgcggcccat cctcgtacga caacgatctc cgcgtcaccc gcgttcgggg ggattcagct
    14881 ctgggcgtgg ccgggaggca gcagtggacc gcactcccac tgctggaaga tcaaccgggt
    14941 ctcgacccgt gccacctcgc gctgcgcggt gaactcgtcg agcaccagcc gctgcagatc
    15001 ggccatgtcc gcgacggcga catgcacgag atagtcgtcc ggcccggtca gatggaacac
    15061 cgtccgggcc tccggcagcg cccggatccg ctcgacgaac gggccgacca gctcccgccg
    15121 gtgcggcctg acctgcacca gcagcagcgc ctgcagcccg cgccccagct tggccggatc
    15181 cagccgcagc tgatggccga ggatcacgcc cgagcggcgc agccgggtca cccggtccag
    15241 acacgtcgac ggcgccacac ccacctgttc ggcgaggtcg cggtaggtga tccgggcgtc
    15301 gttctgcagc agccgcagca gatgaagatc aaccggatcc agtgcgacag attcggccat
    15361 ggctcgaacg tagcacggtg ttcgattccg gtgaatcgtt cactgttcac tcttccgccc
    15421 atggacacag cgaccaccgg tgcctacgac ggcgtacgca ccgcaacgag agccctggcc
    15481 accgaggccg tgcacgccgg ccgcgacgac ctcgcccgcc agggcctgca cgccccgccg
    15541 atcgacctgt ccaccaccta cccctcctac gacagccgcg ccgaggccgc ccgtatcgac
    15601 gccttcgcca ccgacggcgc cgacccggtg ggaccgcctg tctacggccg tctcggcaac
    15661 ccgaccgtcg cccgcttcga gaccgccctg gcccgcctgg agggcaccga gtccgcggtc
    15721 gccttcgcca gcggcatggc ggcgctcagt gccgtcctgc tcgcccgcgc cgcgacgggc
    15781 ctgcgccatg tcgtcgccgt gcggcccctg tacggctgca gcgaccatct gctcaccgcc
    15841 gggctgctcg gcaccgaggt cacctggacc gacccggccg gcatcgccga cgcggtgcgc
    15901 ccggacaccg gcctggtgat ggtcgagtcc cccgccaacc cgaccctcgc cgagctggac
    15961 ctgcgggcca tcgcccacgc ctgcggcgcg gtaccgctgc tcgccgacaa caccttcgcc
    16021 acacccgtgc tgcaacgccc ggccgagcac ggcgcccgta tggtgctgca cagcgccacc
    16081 aagtacctcg gcgggcacgg cgatgcgctc gccggggtgg tcgcctgcga cgaggagttc
    16141 gcgggccggc tccgccagat acggttcgcc accggcggtg tgctgcatcc gctggccggc
    16201 tatctgctct tgcgcgggct gtccaccctg ccggtgcggg tgcgggcggc ctccgcgaac
    16261 gccgccgaac tggtccgccg gctcgccgcc gacccgcgcg tggcccgcgt ccactaccca
    16321 cggctcggcg gcgcgatgat cgccttcgag gtgtacggcg accctcacga ggtcatctcc
    16381 caggtccggc tcgtcacccc ggcggtcagc ctgggcagcg tcgacacgct catccagcac
    16441 cctgcctcca tcagccaccg catcgtcgac gccgacgacc ggcgcggggc cggggtgagc
    16501 gatcggctgc tgcggttgtc ggtggggctg gaggacgtgg acgatctctg ggccgacctg
    16561 gatcaggcgt tgggggaacg tgcccggagg ccggtaccgc ttcaggaagc ggtgcgctga
    16621 gcggtaccgg tcgacggtgg gctgcgcgga gggggcaccg ccggacgccg acgtcgtggc
    16681 tgagcgccgt cgcggcggac gcatctgggc cggcgcaggg tgtgcggttc ggccggggca
    16741 ccgggccgtc gccccgcgtg gccggtgtca gtcgcggcgg gccggatcgc cgagctggtg
    16801 tctggtgtcg tgctgcggcc gggaagcggc cggtacgacg tccaggcggg ccgtgatcac
    16861 cagcgtgccc tcctctatct ggtagtccag cggcaggccg aggccgcgca tcgcggcgac
    16921 catgccggtg ttggaggcct gtgtgacggc gtacacgctc tcgcagcggg cctccacggc
    16981 cagagccacg agccggccga gcagctcgcc gccgatgcca cgctgctgcc agtcgtcctc
    17041 gatcagcagc gcgacctcgg tctcgtcgcc gtcccacagc agatgcccga ggccgactat
    17101 gcggccggag gcggtctgcg cggccagggt gcggccgaaa cgggggctga gcagatggtt
    17161 cagatagcgg tccgcgtcgc tgaccgggcc gtggtagcgc aggccgaggg tgcgcggcga
    17221 gcaccgctcg tgcatcgcct tcgccgcggc cacgtctgag gtgtcgaccc ggcggaccgt
    17281 gatgtcgttg ccctcgggca gcgtcagcac gtccttgccg cgcgggatgc gcggaccgag
    17341 ccggttgtcc agctccacca gggcccgggc cctggcgaac tcggtgggcg tgaacggcag
    17401 atacggccgc tccacggtga gcactccgcc ctccggcgcc cgcagccgca tcacggtgtc
    17461 ctccagcacg ccctcgaccg gcaccggctg cggtccgcgg tccccgccga ccggtgtccc
    17521 gggcagcgaa cggatggtgc accggcccag caactggcgc agcgccagcg gcagttcggc
    17581 ggcgtccagc gcggtgcgcg cggccaggcc gagcacccgg gtgggggcgt cgaccaggtc
    17641 gtgggcatcg gcccgctcga tccaggtgga cgtgccgccg gccagcgaga ccactcggct
    17701 gatctcggcc gccgccagcg cgccgggcgc ccgcagcagg aactcgtcca cggtgccgtc
    17761 ggccagcggg tgcgtctgga ggctcaggat gtcgacgcgc cgctcggcca gcgccgtgca
    17821 cagcgccgcc agcgaacccg gctcgtcctt gaccgtcgtc cgcatccgcc acagggcacc
    17881 ggcggccgcc acgtcgtccg ccggctcgcc cggctgctcg gagggcccgg ccgaccgcgt
    17941 ttcggcggac ggccgggcgc cggtatcttc ggtcggcggt gcgtgtccgt ggcgccgtgc
    18001 ccaccacgtg tggaagccgg cggtcgcggc cagcacgagg gccgagatca ccagcagagc
    18061 ggggccgtcg gggccgtgcc cgatcagatt cgccactccg tcggcgaccg ccaccgcggt
    18121 gaacagggcg gcgagctcca caagatcacg ccgccaatgg tgcacgggcc gaccgtgttt
    18181 cgcccgggtc acatcagaca tgtctgcact catgcaccca ctgtgaagga agggtgttgc
    18241 gtgatcacga actgtttgtg accgatgggt aaagcatgct ccgtcctttt tgtgctcgtt
    18301 ttcacggtct ggtgggcccg catcgtacgg ccccagatcg tggcgttgcc gtcctccgcc
    18361 gacttcggcg cgcagggacg ggaaagggtc atggcctgca gtgatcgcgt catacgaaaa
    18421 ccgtagccgg gaccactgac aatcggtctg acctgcgaaa aggcccgcag agcccaggag
    18481 tttcctaccg gccgacccgg cccggctgga gcgtctgcgt gaacagcacc gtgccgtcgt
    18541 actcacgcag ccggaccgtc atttcgccgc tctcgccgtc gatgtccacc tcgccgaaga
    18601 actggtaccc ctcggcaggc gacacgttcg ctgtggtggg cgccttgacg aacacccggt
    18661 ccgggccgaa cgtgccgtcc agcgcgttgg ccgggaaggc gccggcgttg agcgggcccg
    18721 agacgaactc ccagaacggc tcgaagtcct tgaacgcggc ccgcgagggg tcgtagtgct
    18781 gggcggaggt gtggtgcacg tcggccgtca gccacaccgt gccggtgatc cgccggtgct
    18841 tgatgaagcg cagcagctcg gcgatctgca gctcgcggcc gagcggggcg cccgggtcgc
    18901 cctgcgccac cgcctcgaag tccggcttgc cctccaccgg gtcgggcacg accagcccga
    18961 gcggcatgtc gttggcgatc accttccaca ccgcacggga cttcgccagc tcgcgcttga
    19021 gccactccaa ctgctcacgg ccgaggatgc ccaccgggtc cgcggtctgg ttgtccggcg
    19081 agttcgcgtt gcggtaggta cgcatgtcga gcacgaacac gtcgagcagc gggccgtggt
    19141 tgatgacgcg gtagatgcgg ccgtccgggc gcccgctgat cgtggagatg gggaagtact
    19201 cggagaacgc ctgccgggag cgcggcgcca ggtcgtcgag cctggtgccg gccgggtagg
    19261 gggtgccggt gccgatgacc tcgcctgggt accagttgtt gcgcacctcg tggtcgtccc
    19321 actggatgat gttcggcacc tgggcgttga accggcgcag cgccgagtcc agcaggttgt
    19381 agcggaagtt gccccggtag tcgtccaggg tgaccgcgac gtgcgacttc tcctcggtgg
    19441 tgacgttccg gtagacactg ccgtcgggca ggctcgcggt tgccgcgatc ggaccgtcgg
    19501 cgtagatgtt gtcgccgctg cacaggaaga agtccgggtc ggccttcgcc atggcgtcga
    19561 agatgcggta gccgccgatg gactcgttga tgccccagcc ctgtccggcc aggtcgcccg
    19621 accacacgaa ccgcacatcc cggcgccgct tgaccggcgc cgtacggaag gtgccggtca
    19681 ccggctcgcc ggtgcggcgc gggtcgtccg ggtcggcgag cagcacgcgg tagtggatct
    19741 gctcgccgga ggccaggccg tgcagccggg tggtgccggt gaagtccgtg ccggcgccca
    19801 gcaggggacc gtgccatcgg cgcgggttgc ggaacgactc ggtggccgcg gtctccacga
    19861 tcatccgggc cggccggtcc gaacgaaccc acaccaggcc ggagtcggtg gtcacgtcac
    19921 ctgcttgcac accccagccg gcctgggggc gcccggagcg ggcgaacgcc ggggccgcgc
    19981 cgaggccgcc gggcagggcg annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20401 nnnnnnnnnn nnnnnnnnnn ngggaacgaa cggtctgaca tggctgcgcc tccagggaaa
    20461 ggatccggcc ggtgtgccga ggcaacacct actgggacgc tgcggcgcgt gcggaaacct
    20521 caggtgaaca acggtccttg ggtgctgccc gggctgccgc gccctgtctt ctgggcgccg
    20581 tgcgggctgc ggcgccctgg cttcgcacgg tccgccggcc ggcctctccg acacggggac
    20641 cggccgccag gttcgacccc ctcagcgagc cgggtcccgg tggcgtgccg gtcgtgtcac
    20701 gtccgcgggc cggttcagcg gctgctgccg tccaggatga cccgggcgac cagcgcgggg
    20761 tcgtcgttca tcgggcagtg gccgcagccg ggcagccgca ccagccgggc gtgcgggatg
    20821 agctgcttgg cgcgtacgcc ctgccggcgt acgaggagcc ggtcctgcgc gccccaggcc
    20881 accgtgaccg gcagaccggt cagatcgtcg gtgaaccgga cgctggtgcc cgcccgcagt
    20941 gtcgcgtcga acccggtcgc gcccgccagc gcgagtgtct cggcgaccac ggcttccggc
    21001 gcacgccgcg cggggcgtgc gtagatggtg ctcgtcagcg cggtacggcc ggccgcggtg
    21061 cgcgacagcc gctccaccag cggcagcggg agccgctggg cgatgccccg catcgcgagc
    21121 agcaccgcga aggcgtaccg gcgttcggcg tccgtccaga accctgccgg ggagagggcc
    21181 gtgacggacc gcacgagctt ctcccggccc agctccaggg ccagcaggcc gcccagcgag
    21241 ttgcccgcga tgtgcgggcg gtccagcacc agcgcctcga acagggcgcc gagtacggag
    21301 ttggtggtcg gaaggtcgta ggcgaggccg tccggcaggc ccggggacgc gccgaagccc
    21361 ggcaggtcga cagcgatgac gtcgcgctcg gtggcgagga tgtccacgac cgggtcccag
    21421 gcctgccggt gatggccgat cccgtgcagc aggaccagcg gttccccgcg tcccacgcgc
    21481 gcgtaggaga cggtcacgtc cttcggaccg tgcggggtgg ggaccttgaa ggagacggtg
    21541 gcggacatgg ggtgctcctc gtctgggtgc tggccgacgc tgtagacagc ttgtcagcaa
    21601 ttgctacctg ccggtagccc ccgatgggcg tgcgcagtgc cttcccgcgc cggtcagccc
    21661 gcccggcgta cctcgatgtt gaagtccgcg gtcccgaacc gccgcatcat ggtgagccac
    21721 agcggcagat acatctccac cgtccgggcc gcgcggatgc cgcccaggtc cagcacccgc
    21781 tccgccggcc acccgaactc cccgagcatg gccgtcacct gctccttggc ccccgcgtcc
    21841 tcaccgcaca cgaacaggtg gtgcgcgccc ggcacccgcc ccggatccac catcacctga
    21901 cagttgaccg tgttcagcgt cttcaccacg cgcgtgtgcg ggaaggcccg ctggatctg
//
