LOCUS       NZ_CM002285            22389 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6561105
            Orig. end                         :: 6583494
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22389
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="thioamitides"
                     /region_number="33"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..22389
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="single"
                     /product="thioamitides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22389
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12389](+)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12389
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
     gene            complement(449..865)
                     /locus_tag="M878_RS78120"
                     /old_locus_tag="M878_30750"
     CDS             complement(449..865)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS78120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_30750"
                     /product="hypothetical protein"
                     /protein_id="WP_158692797.1"
                     /transl_table=11
                     /translation="MVSYKEVADLPVKDLISAEDTPVEVTPETSVVEAAKSIGASHQTM
                     AIVEMHGERHSIALHALETAIEQMGGTAQDANVEDVLGKADPVRTVPADTPLKELTAQG
                     VPSETLLVVDPQTDQPQAMISRTELAERVRGLSR"
     misc_feature    849..865
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.78"
                     /tool="antismash"
     misc_feature    complement(931..943)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    1184..1197
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.45"
                     /tool="antismash"
     misc_feature    complement(1185..1198)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.33"
                     /tool="antismash"
     misc_feature    1376..1390
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.22"
                     /tool="antismash"
     gene            1742..2185
                     /locus_tag="M878_RS78125"
                     /old_locus_tag="M878_30765"
     CDS             1742..2185
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142979.1"
                     /locus_tag="M878_RS78125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30765"
                     /product="hypothetical protein"
                     /protein_id="WP_023550857.1"
                     /transl_table=11
                     /translation="MTADTPHMVAAHDQAETHRYTVHFPEHAPREHDPHYRAFEAYRRH
                     TKDTAVCYVGERAGHDSCAGGLELHHAVLEFATANAADPAALHRDFPEIAEDATAEEIA
                     HWLESSPGEFRWLCAFHHRGRGGAHTASHADWTAQLYVPGLIS"
     gene            2185..2370
                     /locus_tag="M878_RS78130"
                     /old_locus_tag="M878_30770"
     CDS             2185..2370
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627627.1"
                     /locus_tag="M878_RS78130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30770"
                     /product="hypothetical protein"
                     /protein_id="WP_023550858.1"
                     /transl_table=11
                     /translation="MGAWLWGAWLQVWPNLAANVLWVPVVGVHHWLTCRHLRALHEQQR
                     HLHHLIEQKESEGQST"
     gene            2367..2594
                     /locus_tag="M878_RS78135"
                     /old_locus_tag="M878_30775"
     CDS             2367..2594
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS78135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_30775"
                     /product="hypothetical protein"
                     /protein_id="WP_023550859.1"
                     /transl_table=11
                     /translation="MSFWRWYWLAWLLIGFAVPETYGLLRNPRATLSETVWSWFGVMRG
                     QSISQWSVQHYVLLVFLFWLLFHLAFRIWR"
     gene            2605..4032
                     /locus_tag="M878_RS49205"
                     /old_locus_tag="M878_30780"
     CDS             2605..4032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141319.1"
                     /locus_tag="M878_RS49205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30780"
                     /product="hypothetical protein"
                     /protein_id="WP_023550860.1"
                     /transl_table=11
                     /translation="MTRFMYDSVSPGNIPAGATMVAGYADGLYANIPDMKARFPHATVV
                     SIAVRWTTRAQVMDVENGDATPAQAVAWCTQTMAATSNHELTVYCDTSTWPAVRAAFKS
                     AGVTEPNYWVAQYDNDPTVPAGAIAKQYQGDTNGYDRSVVADYWPGVDPKPASTETYPG
                     ANTSHWYNAGSNAGVQMQVNTIVWHSTETLALPDYSGGSIAPTLTAVPNWAAQRLDWWQ
                     HFPFDTSARALVHDKTQIGTNTLKCAQVEVVGTCDPATHAAWTKSGIAHLYMPDLPDWA
                     LRDLHAFARWAHDVHAVPLTSGLRWLPYPQSYGANGVRMDTAAWSAWRGHCGHQHVPEN
                     DHGDPGAFPILAVLDPKPAPSAPSYLVTEDDDMTPFAIPPSVDMDIPVEPAGTAQAPQG
                     GARNAGVWIGLAPQGADGKVSVTYHQGGKWAKPTDHTATVAGGKLVLALPTDGSVDKVR
                     VRSAVPLLAYVTGRKVA"
     gene            4032..4301
                     /locus_tag="M878_RS49210"
                     /old_locus_tag="M878_30785"
     CDS             4032..4301
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS49210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_30785"
                     /product="hypothetical protein"
                     /protein_id="WP_023550861.1"
                     /transl_table=11
                     /translation="MMNAPVEKKVQASTVVGLVVGVLVTLANSLAGHSELMGSVPAWLQ
                     SLITLDVPPLATFLAGWLAPHTSRAAPAPEPPAVAPVDAPKVTG"
     gene            4298..4567
                     /locus_tag="M878_RS78140"
                     /old_locus_tag="M878_30790"
     CDS             4298..4567
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061672.1"
                     /locus_tag="M878_RS78140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30790"
                     /product="hypothetical protein"
                     /protein_id="WP_023550862.1"
                     /transl_table=11
                     /translation="MTTPQPPTTVDLLVVLTRLETKLDAATAGIADHETRLRAAEATAL
                     TEEDVQHLRADVEALKRNRWPLPAIGALAGVGGAIAGLVALFQR"
     gene            complement(4850..5284)
                     /locus_tag="M878_RS78145"
                     /old_locus_tag="M878_30795"
     CDS             complement(4850..5284)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061754.1"
                     /locus_tag="M878_RS78145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30795"
                     /product="DUF6233 domain-containing protein"
                     /protein_id="WP_031226097.1"
                     /transl_table=11
                     /translation="MSELPPSPPLPPDAHRLRVILAHLDERLTENETVRIYLHLQRKAV
                     QAALTQAEAPPARRPSRPVKGAKGLPALAQAPNRIGFVVQQKRTPMGPEPALIHVSDCT
                     KIQGTPHRIRADEARAALTDPNIEPCGFCRPDTELGIDVA"
     gene            complement(5265..5471)
                     /locus_tag="M878_RS78150"
                     /old_locus_tag="M878_30800"
     CDS             complement(5265..5471)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500403.1"
                     /locus_tag="M878_RS78150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30800"
                     /product="hypothetical protein"
                     /protein_id="WP_023550864.1"
                     /transl_table=11
                     /translation="MSPIPDDLARAQEEWHATYRQLAVRPRTALRQQLIHLSSEVLFHP
                     YWQGRRSAAWAALHGAPYVRAAS"
     gene            5537..6178
                     /locus_tag="M878_RS78155"
                     /old_locus_tag="M878_30805"
     CDS             5537..6178
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010032644.1"
                     /locus_tag="M878_RS78155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30805"
                     /product="HAD family hydrolase"
                     /protein_id="WP_023550865.1"
                     /sec_met_domain="HAD_2 (E-value: 3.6e-12, bitscore: 45.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIETIVFDVGETITRDDRYWASWADWLNVPRHTLSALVGAVVAQG
                     RDNAEALRLVRPGIDVLAEYQAREAAGRGEGLDESDLYPDVRPALSALKDHGVRVIIAG
                     NQTARAGELLRGLDLPADLIATSGEWGFAKPQPEFFQRVMEVAHSTPSATLYVGDHPAN
                     DVVPAKAAGMRAAHIRRGPWGHLWAQDADVVAAADWRIDSLTQLVAIVDG"
     misc_feature    5556..5576
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.92"
                     /tool="antismash"
     gene            6284..7471
                     /locus_tag="M878_RS78160"
                     /old_locus_tag="M878_30810"
     CDS             6284..7471
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019360061.1"
                     /locus_tag="M878_RS78160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30810"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_031226099.1"
                     /transl_table=11
                     /translation="MPARPRGGVGARIAYYRSVMRPKLTQQQLAEASCVALGTIRKIER
                     GERGVSDSTLEAIADALGIDPARLCSDRESVQTRVHDALPVLSAAIAAYDVPDDGPVRP
                     LHELREVVDAAVSWRLAARYTRIARELPDLLAELARGYHQAPAAEQAELAGLLVRAYRA
                     ADAVAYKFGARDLSARLVDLMRWAAPAADDPLLAASVAYVRTETFFAARAHTPGLRALE
                     HALDAVPAPATAPEIAARGALHMRAAVIAGRARDTGAAAGHLDEARALADQVSEDVYCG
                     TAFGPDSVRIHEVSVSVSLGDEHVSRALDVAGEWKPPRDLPAERRSGFYIELARAQLWS
                     GLADDAFESLKVARHIAPQHTREHPWVREDAGTLRRLKRADAETLSNFAEWCAAT"
     gene            7567..7764
                     /locus_tag="M878_RS78165"
                     /old_locus_tag="M878_30815"
     CDS             7567..7764
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS78165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_30815"
                     /product="hypothetical protein"
                     /protein_id="WP_023550867.1"
                     /transl_table=11
                     /translation="MPDTLSLAPTVIDGRVSIVRLHGEACFDCGAVNKTLREAGHVVVR
                     GSTRVWQIVTCGCRSKANAV"
     gene            8076..8438
                     /locus_tag="M878_RS78170"
                     /old_locus_tag="M878_30820"
     CDS             8076..8438
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS78170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_30820"
                     /product="hypothetical protein"
                     /protein_id="WP_023550868.1"
                     /transl_table=11
                     /translation="MHAAVGSDDPQAVADAVAHHLRGPVIYDVLVAGPTYWALVPYWPA
                     ITWTGTAETPLLGPGSFLGVPDVEVTEPPGSYWVRPPRNRHDLCQREAVFDFILRGRRQ
                     LRAQEEPATTALELGR"
     gene            8435..8905
                     /locus_tag="M878_RS78175"
                     /old_locus_tag="M878_30825"
     CDS             8435..8905
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS78175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_30825"
                     /product="hypothetical protein"
                     /protein_id="WP_023550869.1"
                     /transl_table=11
                     /translation="MTVLSTEEMERLHRLVSWEMPSGMTTAAAAGKACVWCGGPLGEDR
                     ARLQTSVPRLGCGRCYSARLAWYITWYDWHRHVSSCTTACQQARVCHVGYGLRAVHDVT
                     IAAAGKEAPQCVSCHHPIHVGEMTVPVRWEGTSQDHLGYAHTQCVMTRAAVR"
     gene            8902..9570
                     /locus_tag="M878_RS78180"
                     /old_locus_tag="M878_30830"
     CDS             8902..9570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142283.1"
                     /locus_tag="M878_RS78180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30830"
                     /product="hypothetical protein"
                     /protein_id="WP_023550870.1"
                     /transl_table=11
                     /translation="MSSTGVRPVLYRDGTPVPFITAWSGEHMPSQPVAEVCRRGGTGLG
                     FVDEQIHVDRQYGALWVRMPAVRTGQPELRAVHALRQRQAMSRLLCQMCGGPTVGIRDD
                     ERTLFLMGAAGGHPICEGERTSSPPVHPVCARLAVENCPRLRRGWAAALVSYTPVWGVQ
                     GVMYSPKTLEPEPDVSVSFMDARRLRWVLASRLLVTLEGVTAVNDLDALCEDSEFTEMV
                     "
     gene            10001..11254
                     /locus_tag="M878_RS78185"
                     /old_locus_tag="M878_30840"
     CDS             10001..11254
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700245.1"
                     /locus_tag="M878_RS78185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30840"
                     /product="TfuA-like protein"
                     /protein_id="WP_023550872.1"
                     /sec_met_domain="TfuA (E-value: 2e-40, bitscore: 136.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHVFVGPTLRRSEALLAVSGLRVRPPVRHGDLFAAAIGIGDTVV
                     IIDGVYHQAPALRHKEILAAMGRGLRVIGAASIGALRAVELAPYGMLGVGRIYTAYARG
                     DIDGDDEVAVGQAPDGEWDALTWPVVNLRHVLDLARSAEILDGERAARLLEALRAVHYP
                     QRTWAAVRAVCRRQGQTAFADWLAEQTERDQYFGDLKRADALAAVRTALDGFTPPGAAR
                     PAPHSWESPYFRRWSNAFARTRVDGLDLSTEDRLIYQQVFDPDFRETWTAYLEHRSLRP
                     ADGSPGLPLKTRSAQVTGGTLPAHQVFHPTVDLRDEATVALLLAGEACEDRAAVARYAD
                     TLAAVRRSRPGFSTAAVRDDLARRMLLRVWRCSEHLFDEEASARGLVCGARAVEAAKRL
                     VPGYLAESERMEATSAAQ"
     gene            11280..12389
                     /locus_tag="M878_RS78190"
                     /old_locus_tag="M878_30845"
     CDS             11280..12389
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347379.1"
                     /locus_tag="M878_RS78190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30845"
                     /product="YcaO-like family protein"
                     /protein_id="WP_051430309.1"
                     /sec_met_domain="YcaO (E-value: 3.4e-61, bitscore: 206.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRARPPEETWQTLAGLLPSYGITRVARLTELDCIGLPVWTAIRPA
                     SMTLSTSQGKGATDLLAKLSAVMEAIELWHVEQPLPIAVRGSAVEVAPDYPVSALPLIV
                     PYPEETLTRLVWEWTPGTGLMSGEKVLLPVALVRRRAQRPEWSPNLLRATSTGLACGNT
                     RDEALLHALFEVVERDVLFQDGQCGGQRRTLIDPATVDDPYGREVIDRLSSAGMALELS
                     LVDGPYGIPVCLAYLWSEDFPVVFAGGGCHSSPVIALTRALTEAAQSRLTAIAGTRDDL
                     PSDLAWFDTPPLSPAQRTGLAVWPEATTHFASGPGDFADQVRDVARRVELITGYEPMTL
                     DLSDARAPVYAVQVVCPGTRSRIRRAMPR"
     gene            12386..13264
                     /locus_tag="M878_RS78195"
                     /old_locus_tag="M878_30850"
     CDS             12386..13264
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477227.1"
                     /locus_tag="M878_RS78195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30850"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_023550874.1"
                     /transl_table=11
                     /translation="MTLHSVTPAAPQSQQLAAQYDALHAARARTPLVARLYAEAMGEDY
                     PLEVNASSSCDWPLLGLMTARLRMRPGQLLVDAGCGSGGIGLWLARALATRLVGFDVSP
                     VAVAQATARRPGFVSAERAAFRVARLEASGLPDGCAHGAVCVDALSGAADRTAALRELG
                     RLLAPGGRLLATRGLRPGVTPTWEKQARAAGLILESVDERPAEPVMWERLYRLWIAHAE
                     ELRCELGDLPAQNMLIEAHRMLPVLPGRRAVLLTLRRASTSPSVPDAAGTMTQPSRPQG
                     GGSVSTERTPQ"
     gene            13261..14274
                     /locus_tag="M878_RS78200"
                     /old_locus_tag="M878_30855"
     CDS             13261..14274
                     /EC_number="1.1.1.94"
                     /GO_component="GO:0009331 - glycerol-3-phosphate
                     dehydrogenase complex [Evidence IEA]"
                     /GO_function="GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0046167 - glycerol-3-phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020556962.1"
                     /locus_tag="M878_RS78200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30855"
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="WP_023550875.1"
                     /transl_table=11
                     /translation="MSQNRPARAAVFSAGSWGTAVAKILADAGTDVIVHARRSEIADAI
                     NTHHRNPGYFPDIELPAALTATTDPATALDGPDFLVLSIPAQTLRTNLAAWAPHIGDDT
                     VIVSLMKGIEQSSHLRASQIITEVTGLSADRVAVLSGPNLAREIMDGRPAAATVACPDE
                     DAARRFQQACHTPYFRPYTSTDVAGCELGGAVKNVIALAVGIASGMGLGDNATAMLITR
                     GLAETTRLAMALGAHPATLAGLSGMGDLVATCSSPLSRNRTFGTHLGRGLSVEQAAAAT
                     RQTTEGVKSAEAILALAHAHDIEMPITEVISTLLHEKVTLAQAAAALMQRPPKPER"
     gene            14345..14701
                     /locus_tag="M878_RS78205"
                     /old_locus_tag="M878_30860"
     CDS             14345..14701
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019527695.1"
                     /locus_tag="M878_RS78205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30860"
                     /product="hypothetical protein"
                     /protein_id="WP_023550876.1"
                     /transl_table=11
                     /translation="MHMSVLSAVQIAVTLGLVAWMITGFTRLPGRWLRWKMFCRATFTI
                     ISLTGTTKDGCTEPVNVYDYLSPGSFILGPPQLQTILDHLTGSGRYDRIDGHGRVLSAR
                     GEQPVEVRDGRVVL"
     gene            14688..15542
                     /locus_tag="M878_RS78210"
                     /old_locus_tag="M878_30865"
     CDS             14688..15542
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134989.1"
                     /locus_tag="M878_RS78210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30865"
                     /product="hypothetical protein"
                     /protein_id="WP_023550877.1"
                     /transl_table=11
                     /translation="MWFFDAFTSGFQHTTDPGRLQWFRIIFGTVLTLRFALAFGQGGWD
                     RFASASLSAHLAEQRFGAVRTRLLVTVYRPALIVRTAAALALALGPGPRLALLVVLPGA
                     AMELLYLKSPNAIRYILLTGTCLLLAGDLGHGLHVEHGLSEANTWAQCLLVLITTDIYW
                     NSAWQKIRSPQFRTGLYLAQWMHVYAQVRDQLPYGGQYAIPGFVRRHMGNLADRDVRLW
                     RLIATTVIAMEIALPPTLLIPQTTPYAVVAGAGMHAAFTCLKPRQLLTFSGLTVGTYLA
                     FLA"
     misc_feature    15606..15619
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            15725..15985
                     /locus_tag="M878_RS96740"
                     /old_locus_tag="M878_30870"
     CDS             15725..15985
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS96740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_30870"
                     /product="hypothetical protein"
                     /protein_id="WP_245238238.1"
                     /transl_table=11
                     /translation="MRRSQLYQELRQFHGSAYQDPELIRLAAPRVALISCGADNPYGHP
                     APATVAALRAGGALVLRTDRDGELAVGGTGGAGGKVMVTRD"
     misc_feature    complement(16001..16014)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            16014..16850
                     /locus_tag="M878_RS78215"
                     /old_locus_tag="M878_30875"
     CDS             16014..16850
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019064179.1"
                     /locus_tag="M878_RS78215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30875"
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_023550879.1"
                     /transl_table=11
                     /translation="MNPSQADAYLRRIRAERPQRPTGPALRELHLRHLQTVPFENLSIH
                     FGEEIVLEEERLLVKVTGRRRGGFCYELNGAFGALLAALGYEVELLAGRVYGDEGRLGI
                     PYDHLALRVRTVEGDTWLADVGFGAHSHYPLAYAERGEQADPGGVFRVVEAGPDAAGVR
                     GGGSGGAGDLDVVRNGRPQYRLEARPRVLGDFVAAAWWHSTSPVSHFTRSLVCSRATED
                     GGRVTLSGRSLTTTDADGKRGTRELGTDEEVLAVYRERFGIELDCVPTVRSRSFYS"
     gene            17001..17246
                     /locus_tag="M878_RS78220"
                     /old_locus_tag="M878_30880"
     CDS             17001..17246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660443.1"
                     /locus_tag="M878_RS78220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30880"
                     /product="hypothetical protein"
                     /protein_id="WP_037730210.1"
                     /transl_table=11
                     /translation="MSDVRHVLVLPDRDAAEEAAEALGERFGLDEEPRLVRDALAGEDD
                     AEDAQWLVVLRDEDERLDPAELDEFVGEWDGWREEP"
     gene            17402..18391
                     /gene="holA"
                     /locus_tag="M878_RS78225"
                     /old_locus_tag="M878_30885"
     CDS             17402..18391
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /gene="holA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672659.1"
                     /locus_tag="M878_RS78225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30885"
                     /product="DNA polymerase III subunit delta"
                     /protein_id="WP_031226107.1"
                     /transl_table=11
                     /translation="MARKTANDDPLAPVTLAVGQEDLLLDRAVREVVAAAKAADADTDV
                     RDLTPDQVQPGTLAELTSPSLFAERKVVVVRNAQDLSADTVKDVKAYVGAPAEEITLVL
                     LHAGGAKGKGLLDAARKAGAREVACPKMTKPADRLAFVREEFRSFGRSAAPEACQALCD
                     AIGSDLRELASAVSQLVADVEGTIDEAVVGRYYTGRAEASSFTVADRAVEGRTAEALEA
                     LRWSLATGVAPVMITSALAQGVRAIGKLSSARGGRPADLARELGMPPWKIDRVRQQMRG
                     WTPDGVAAALRAVAEADAGVKGGGDDPEYALEKAVVIIARAARSRGRG"
     gene            complement(18801..19067)
                     /gene="rpsT"
                     /locus_tag="M878_RS78230"
                     /old_locus_tag="M878_30890"
     CDS             complement(18801..19067)
                     /GO_component="GO:0000312 - plastid small ribosomal subunit
                     [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010355388.1"
                     /locus_tag="M878_RS78230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30890"
                     /product="30S ribosomal protein S20"
                     /protein_id="WP_023550882.1"
                     /transl_table=11
                     /translation="MANIKSQIKRIKTNEKARLRNKAVKSSLKTAIRKAREAVAAGDVE
                     KATVAVREASRKLDKAVSKGVIHKNQAANKKSALASKVTSLKG"
     misc_feature    complement(19281..19290)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     gene            19300..21174
                     /gene="lepA"
                     /locus_tag="M878_RS78235"
                     /old_locus_tag="M878_30895"
     CDS             19300..21174
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976242.1"
                     /locus_tag="M878_RS78235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_30895"
                     /product="translation elongation factor 4"
                     /protein_id="WP_031226109.1"
                     /transl_table=11
                     /translation="MPATPNHVPEPSRTAPALIRNFCIIAHIDHGKSTLADRMLQLTGV
                     VEQRQMRAQYLDRMDIERERGITIKSQAVRLPWAPTEGPDQGTTHILNMIDTPGHVDFT
                     YEVSRSLAACEGTILLVDAAQGIEAQTLANLYLAMENDLTIIPVLNKIDLPAAQPEKFA
                     EELANLVGCDPEDVLKVSAKTGLGVDALLNKVVKEIPAPVGVADAPARAMIFDSVYDSY
                     RGVVTYVRVIDGQLNKRERIRMMSTGATHELLEIGVNSPEMLPADGLGVGEVGYLITGV
                     KDVRQSKVGDTVTSQSKGATEALGGYKDPKPMVFSGLYPLDGSDYPELREALDKLQLND
                     AALVYEPETSAALGFGFRVGFLGLLHLDVIRERLEREFGLDLIATAPNVVYRVVMEDGS
                     EHTVTNPSEFPEGKINEVFEPVVRATILAPTEFIGSIMELCQTRRGTLLGMDYLSEDRV
                     EIRYTLPLAEIVFDFFDQLKSKTRGYASLDYEPTGEQTSSLVKVDILLHGDKVDAFSAI
                     THRDQAYAYGVRLVAKLKELIPRQAFEVPVQAAIGSRVIARETIRAIRKDVLAKCYGGD
                     ISRKRKLLEKQKEGKKRMKMVGSVEVPQEAFIAVLSSDDSAGSAKGKK"
     misc_feature    21350..21367
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     misc_feature    complement(21363..21378)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.1"
                     /tool="antismash"
ORIGIN
        1 agcccatctt taacgcggtg caggccagca cgacggacac gctgaccagt ggcatctcgt
       61 ggacgtcgct gaccttcaag gactccgccg gtatctacca ggacacctac ggcggccact
      121 ccctcacgac caaccccagc cggtacgtcg ctcaggtcgc cggctggtac acgatcaacg
      181 gctgcgccac gttcagcacc accagcacga ccggcgagcg cggtgtgcgc atcgccaaga
      241 acggcaccca ggttcagggc atgtgcacca tgctccaggc gcccacaacc accagcgttt
      301 caccggcgat ccccaccccg acccgcgacg tcttcctcaa cgcaggcgac tacgtcgagg
      361 tgcaggccct ccagaacagc ggggtccagc tcaccaccat cgccggtacc gacctgtcca
      421 gcggcctcta tgtccgcttc tctcacgtct agcgggaaag gccccgaacg cgctcggcca
      481 actcagtgcg actgatcatc gcttgcggtt ggtcggtttg cgggtcgacg acaaggagtg
      541 tttcggaggg gacaccttgc gcggtcaatt ctttaagcgg cgtgtctgcg ggaaccgttc
      601 tcaccgggtc cgctttcccg agcacgtcct caacgttagc gtcttgagcg gtgcctccca
      661 tctgctcgat agctgtctcc aacgcatgga gggcaatact gtgcctctct ccatgcatct
      721 ctacgatggc catggtctgg tgacttgccc cgatgctctt agccgcttcg acaactgaag
      781 tttcaggcgt gacctcgaca ggcgtatcct cagcggaaat cagatctttt actggaaggt
      841 ctgccacttc cttgtaagaa accattgcca cacctcgcct tcacgatcca ggtgtggagg
      901 agccaggatt ctgcaaatga tcagccaggc ttgcaacctg cgaaccctga cccctcaact
      961 gagccactat cgacggccag ccagccccta caaccaaggc ctgggggatg gccacgtcac
     1021 tcccattggg gacttgtagc acggctgcga gcacagcacc aaaaacgacg tatcccgcaa
     1081 cctttgccgg gctccgacgc gttgtcgcca tctttccatc gtgcgccgga accaacttct
     1141 cgaaactcgc gcgaagtcgc gcgatgtccc tgtcctcaac agcatttaaa tagacaatca
     1201 cgatgaatgc agaggcacca ataaggccga ggatccccgc aacgagggtg ctccatttaa
     1261 ggaagtcttg ccaggctgtc gccagaaaca tgtccactcc aacccgggct ctgattgaca
     1321 tcaatggcct atcggagcgt gcactcttgt ctaagagtaa gcccacgcaa cagatttcgc
     1381 attttgggta cgcgctcctc gcctcaccgc ccccgttcga gtgctcgacg cagcagagca
     1441 gcagccagac gtagttcacg attagtgtgt ccgcaggcga cgacggcggc agcctcagct
     1501 tctactccag cgccatcacc gacgccttcg tcctcagcct ggcctgagac cctccgcgag
     1561 gtgacgtggc cggcgggcgt caccgcgcag gtcaccgcgt acaaggccac cacggagatc
     1621 cattcgtact ccaccgacct gacgcaggcc cagcccgtct tcagctgacc tggccgcctg
     1681 ctccctgccg cccccgcagc gtcgggggct tcttcatgcc cacgcccaat ccgaggacac
     1741 gatgaccgca gacacgccgc acatggtggc ggcccacgac caggccgaga cacaccggta
     1801 caccgtccac ttcccggagc acgctccgcg cgagcacgac ccgcactacc gggctttcga
     1861 ggcgtaccgc cgtcacacga aagacaccgc ggtctgctac gtcggcgagc gcgccggaca
     1921 cgactcctgc gccggcggcc tggagctgca tcacgccgtc ctggagttcg cgacggccaa
     1981 cgccgccgac ccggctgccc tgcaccgaga ctttccggag atcgccgaag acgccaccgc
     2041 cgaggagatc gcgcactggc tcgaatcctc gcccggcgag ttccgctggc tgtgcgcctt
     2101 ccaccacagg ggccgcggcg gcgcccacac cgcctcccac gccgactgga cggcacagct
     2161 atacgtcccg gggctcatct cctgatgggc gcctggctgt ggggcgcgtg gctccaggtg
     2221 tggccgaacc tggccgcgaa cgtgctgtgg gtgcccgtcg tcggcgtcca ccactggctg
     2281 acctgccgcc acctgcgcgc gctgcacgag cagcagcgcc acctgcacca cctgatcgag
     2341 cagaaagaga gcgagggcca gtcgacatga gcttctggcg ttggtactgg ctggcctggc
     2401 ttctgatcgg gttcgccgtg ccggaaacct acggcctgct gcgcaacccg cgggccaccc
     2461 tgtccgaaac ggtgtggagc tggttcggcg tgatgcgcgg ccagtcgatc tcgcaatgga
     2521 gcgtccagca ctacgtgctg ctcgtcttcc tcttctggct gctcttccac ctggcgttcc
     2581 ggatctggcg ctgagggggc gacgatgacg cggttcatgt acgactccgt ctcgccgggg
     2641 aacatcccgg cgggcgcgac gatggtggcc gggtacgcgg atggcctgta cgccaacatc
     2701 cccgacatga aggcccggtt cccgcacgcc acggtcgtca gcatcgcggt tcggtggacg
     2761 actcgcgcgc aggtgatgga cgtcgagaac ggtgacgcca ccccggcgca ggccgtggcc
     2821 tggtgcacgc agacgatggc cgccacctcg aaccacgaac tgaccgtgta ctgcgacacg
     2881 agcacatggc cggccgtccg ggcagcgttc aagtcggccg gggtgaccga gccgaactac
     2941 tgggtcgccc agtacgacaa cgacccgacc gtcccggccg gtgcgattgc caagcagtac
     3001 cagggcgaca ccaacggata cgaccggagc gtggtggccg actactggcc cggcgtggac
     3061 ccgaagcccg cgagcaccga gacgtaccct ggggcgaaca cgagccactg gtacaacgcc
     3121 ggctcgaacg cgggcgtaca gatgcaggtc aacacgatcg tctggcacag cacggagacg
     3181 ctcgcgctgc cggactactc cggcgggtcg atcgcgccga cgctcacggc agtgccgaac
     3241 tgggcggccc aacggctcga ctggtggcag cacttcccgt tcgacacctc cgcccgcgcc
     3301 ctggtccacg acaagacgca gatcggtacc aacacgttga agtgcgcgca ggttgaggtc
     3361 gtgggcacgt gcgacccggc cacgcacgcc gcctggacga agtcgggcat cgcccacctc
     3421 tacatgcccg acctgccgga ctgggcgctc cgtgacctgc acgcgttcgc ccggtgggcg
     3481 cacgacgtcc acgccgtccc gctcacctcc ggtcttcggt ggctgccgta cccgcagtcc
     3541 tacggggcga acggtgtccg catggacacc gccgcctggt cagcgtggcg cgggcactgc
     3601 ggccaccagc acgttcccga gaacgaccac ggcgacccgg gcgccttccc gatcctcgcc
     3661 gttctcgacc cgaagcctgc accctcggcg cccagctacc tcgtcacgga ggacgacgac
     3721 atgaccccct tcgccattcc gcccagcgtc gacatggaca tccccgtcga gcccgccggc
     3781 accgcccagg ccccgcaggg cggcgcacgc aacgctggcg tctggatcgg cctggccccg
     3841 cagggcgccg acggcaaggt cagcgtgacc taccaccagg gcggcaagtg ggccaagccc
     3901 accgaccaca ccgcgaccgt ggccggcgga aagctcgttc tcgcgctccc gacggacggc
     3961 agcgtcgaca aggtccgcgt ccgctccgcc gtgccgctcc tcgcctacgt caccggaagg
     4021 aaggtcgcct gatgatgaac gcgcccgtag agaagaaggt ccaggcgtcc actgtggtcg
     4081 gcctggtcgt cggcgtcctg gtgacgctcg cgaactccct ggccgggcac agcgagctga
     4141 tggggtccgt gcccgcgtgg ctccagtcgc tgatcaccct ggacgtgccg ccgctcgcaa
     4201 cgttcctggc tggctggctc gctccgcata cgtcgcgggc ggcgcctgcc cccgagccgc
     4261 cggcggtcgc ccccgttgac gcgcccaagg tgacgggatg accacgccgc agccgccgac
     4321 aaccgtcgat ctcctggtag tgctcacccg gctggagacc aagctcgatg ctgccacggc
     4381 cggtatcgcc gaccacgaga cccggctgcg tgctgcggag gcaaccgccc tgaccgagga
     4441 agacgtgcag cacctacggg ccgacgtgga ggccctgaaa cgcaatagat ggccgctgcc
     4501 cgcgatcggc gccctggcgg gagtcggcgg agccatcgcc gggctcgtcg ccctctttca
     4561 gcgctgatct gtgcaacgca tcgccccctg cacggccgtt gggccgtgca gggggatttt
     4621 tcgcatgttc ggagtcttgc gtctttcggt catggtggcg cattgtggtc gccccgccgc
     4681 ctcaccggag tcgtccagat ccggctctcc tgggggcggt gggctgtccc ccttcgccat
     4741 ccccccggtg gaagaggtga caccagcccc tgcggctcgc cgagccgtag gggctcaatc
     4801 gtcgtccccc tgcccggccc gctccacgcc cgccatccgg gcccggtgct cacgccacgt
     4861 cgatgcccag ctcggtgtcc ggccgacaga agccgcaggg ttcgatgttc gggtcagtga
     4921 gtgcggcgcg cgcttcgtcg gccctgatcc ggtgcggcgt gccctggatc ttcgtgcagt
     4981 cgctgacgtg gatcagggct ggttcgggcc ccatgggggt gcgcttctgt tgaaccacga
     5041 acccgattcg gttcggcgcc tgagccaggg cagggagccc cttggctccc ttgaccggcc
     5101 gacttgggcg tctcgcggga ggggcctcgg cttgggtgag tgccgcctgc actgctttcc
     5161 gctggagatg gaggtagatg cggacggtct cgttctcggt gagccgctcg tcgaggtgcg
     5221 cgaggatcac ccggagccgg tgggcgtcag gcggcagcgg cgggctagga ggcagctcgg
     5281 acataggggg caccgtgcag cgccgcccag gccgctgacc gccgaccctg ccagtacggg
     5341 tggaacagca cctccgacga caggtggatg agctgctgcc ggagcgcggt gcgcggtcgt
     5401 acggcgagct gccggtaggt ggcgtgccat tcctcttggg cgcgtgcgag gtcgtcgggg
     5461 atcgggctca tgccccagat tcaatcatgt gttcgatttt ctgcgcatct tggcgtgcga
     5521 gccgtaggct caccgcgtga ttgagaccat cgtgttcgac gtcggcgaga cgatcactcg
     5581 cgacgaccgc tactgggctt cgtgggcgga ctggctcaat gtcccgagac acacgctgtc
     5641 cgccctcgtc ggagctgttg tcgcgcaggg ccgggacaat gccgaagcgc tccggctcgt
     5701 gcggccgggg atcgacgtcc ttgccgagta tcaggcccga gaggcggccg gccgcggtga
     5761 aggactggac gagagcgacc tgtatcccga cgtccggcct gcgctatcgg cccttaagga
     5821 tcacggcgtg cgcgtgatca ttgcggggaa ccagacggcc cgtgcaggtg aactgctgcg
     5881 cggcctcgat cttccggcag acctcatcgc cacctccgga gagtggggtt tcgcgaagcc
     5941 tcagccggag ttctttcagc gggtaatgga ggtggcgcac tctacgccga gcgcgactct
     6001 gtacgtcggt gaccatcccg ccaacgacgt ggtcccggcg aaagcggctg ggatgcgcgc
     6061 cgcacatatc cgtcgtggcc cgtgggggca tctgtgggca caggacgctg atgtcgtagc
     6121 tgctgccgac tggcgaatcg acagtctcac ccagctcgtc gccatcgtcg atggctgagc
     6181 agtaacttgc cctgccagcc gagcagttgg tggggccgtt tgtgtgcaca ccgagtctcg
     6241 acgtgggtac tgttcggagt ggttgcaccg aactggagcc gagatgcccg cacgccctcg
     6301 tggtggggta ggcgcccgaa tcgcctacta ccgcagcgtc atgcgcccga agttgacaca
     6361 gcagcagctc gccgaggctt cctgcgtagc ccttggcacg atccggaaga tcgagcgcgg
     6421 cgagcgcggc gtaagcgaca gcacgctcga agccatcgcc gacgctctgg gcatcgatcc
     6481 cgcacggctc tgctcggatc gagagtccgt gcaaacgcgg gtccacgacg cgctaccagt
     6541 actgtccgcc gcaatcgccg catacgacgt tcccgatgac ggaccggtgc gtcccctcca
     6601 cgagcttcgc gaggtggtcg atgcggctgt cagctggcgc ctcgcggcgc ggtacacgcg
     6661 aatcgcccgc gagctgccag acctgctcgc tgaactcgcc cgcggctacc accaggcccc
     6721 ggccgcggaa caagctgaac tggctggact cctcgtcagg gcctaccgcg cagccgacgc
     6781 cgtggcctac aagttcggcg cccgcgacct gtccgcacgg ctggtcgacc tcatgcgttg
     6841 ggcagctccc gcagccgatg atccgctctt ggccgcgtcc gtcgcatacg tacgcacaga
     6901 gaccttcttc gccgcccgcg cgcacactcc cgggctccgg gcccttgagc atgctctgga
     6961 cgcagtgcca gcccctgcca cggcccccga gatcgcggca cgaggcgccc tccacatgcg
     7021 ggcagcggtc atcgccggcc gcgcccgtga caccggggcc gccgccgggc acctggacga
     7081 agcccgagca ctggctgatc aagtctccga ggacgtgtac tgcggaacgg ccttcgggcc
     7141 cgactcagtt cggattcacg aggtatccgt ctccgtcagc ctgggagatg agcacgtcag
     7201 ccgagcgctc gacgtcgcgg gcgagtggaa gcctccgaga gacctccctg ccgaacgtcg
     7261 cagcggcttc tacatcgaac tcgcccgcgc ccaactgtgg tctggactcg cggatgacgc
     7321 attcgagtcc ttgaaggtcg cccggcacat cgcgccccag cacacccgcg agcacccatg
     7381 ggtgcgagaa gacgcgggca cgctccggcg gctcaagcgt gcggacgctg agaccctctc
     7441 caacttcgcc gagtggtgcg cggccacctg agccactacc cctctacccc tcgctggggt
     7501 acttgtgcct ttccacagcc cccaccatct gttccacgcg taggaaccag cagatgggag
     7561 cggggaatgc ctgacacact ctcgctcgcg cccacggtca tcgacggccg cgtgagcatc
     7621 gtccgactgc acggtgaggc ctgcttcgac tgcggagcgg tcaacaagac cctgcgcgag
     7681 gctgggcacg tcgtcgtccg gggcagcacc cgcgtgtggc agatcgtcac atgcggatgc
     7741 cgcagcaagg cgaacgccgt gtgaacgcca aagccaccca ccgcgagacc ccggcgaccg
     7801 cgcgaacggc cccgggggat ggccgactag taggagtcga catggcgcac cgtatcgccc
     7861 cggaaagagg ggcgacactg ctacttccgc ttcctccgca attcccattg cccgtccgga
     7921 gcgataggcg ccccgactcg ccggagacta tccggacctg gctcgcaggc gctcaccgct
     7981 cgaccgagca ggcccgccgc gaatggcaga cgcaggggct cgcgatactg ccgctcggcg
     8041 ccgggtgggg cgcggtccgg atccccggaa ctatcgtgca cgcggccgtc ggcagcgacg
     8101 acccgcaggc cgtcgcggac gccgtggcac atcacctgcg cggccccgtc atctacgacg
     8161 tgctggtggc aggccccacc tactgggcgc tcgtaccgta ctggccggcc atcacctgga
     8221 ccgggaccgc tgagacgccc ctgctcggcc ccggcagctt cctcggcgtg cccgacgtcg
     8281 aggtcaccga gccgcccggc tcgtactggg tcaggccgcc ccgtaaccgc cacgacctct
     8341 gtcagcgcga ggccgtcttc gacttcatcc tgcgcggccg ccgccagctg cgcgcgcagg
     8401 aagagcccgc cacgacggcc ctggagctgg gccgatgacg gtactgagca ccgaggagat
     8461 ggagcggctg catcggctcg tctcctggga gatgccctcg ggcatgacca cggcagctgc
     8521 agcgggcaag gcctgcgtgt ggtgcggcgg accgctcggc gaagaccgcg cgcgccttca
     8581 gaccagtgtc ccgcgcctgg gctgtgggcg gtgctacagc gctcggctcg cctggtacat
     8641 cacctggtac gactggcacc gccacgtcag cagctgcacc acggcgtgcc agcaggcgcg
     8701 tgtctgccac gtcggctatg gcctccgcgc cgtgcacgac gtgaccatcg ccgccgcggg
     8761 caaggaggcc ccgcagtgtg tcagctgtca ccaccccatc cacgtgggcg agatgacggt
     8821 gcctgtgcgc tgggaaggga cgtcccagga ccacctgggc tacgcacaca ctcagtgcgt
     8881 gatgaccagg gcggccgtcc gatgagcagc acgggtgtcc gtccggtcct gtacagggac
     8941 gggacgccgg tccccttcat caccgcctgg tccggggaac acatgccgtc ccagccggtg
     9001 gccgaggtct gccgccgcgg tggcaccggg ctcggcttcg ttgacgagca aatccacgtt
     9061 gaccgccagt acggcgccct gtgggtgcgc atgccagcgg tgcgcaccgg gcagcccgag
     9121 ttgcgggccg tccatgctct ccggcagcgg caggccatga gccgactcct ttgccagatg
     9181 tgcggtggcc ccaccgtcgg catccgggac gacgagcgca cgctcttcct catgggagcg
     9241 gcgggcgggc accccatctg cgagggtgag cgcacgtcct cgccgcctgt gcacccggtg
     9301 tgtgctcgcc tcgccgtgga gaactgcccg cgccttcgcc gggggtgggc cgcagcgctc
     9361 gtctcgtaca cgcccgtgtg gggggtccag ggcgtcatgt acagcccgaa gacgcttgag
     9421 cccgagcctg acgtcagcgt ctccttcatg gacgcccgtc gcctgcgctg ggtgctcgcc
     9481 tcccgcctcc tggtcaccct ggagggcgtg acggccgtca acgatctcga tgccctctgc
     9541 gaggacagcg agttcacgga gatggtctga cgtgcctccg ctcccggccg cgacgccgac
     9601 cgcgccagta gccgccgcgc ccgccctggc acaaagggcc ccatggcgac cgcagggtca
     9661 gggtcgcatc ccaaaccccc gtctcgtcgg cctccgcaag agccggcgag acgggccacc
     9721 cgtcccgtcg gcgtcctgca tgtcgagtcg tcggcgggag gggttcaacc acaaaggcaa
     9781 tcccgaggag gaatcacatg acgtccgttt cccagtccga aggcgtcgcc cctgcggtgt
     9841 cggccgagca ggccgaggag atcaccggga ccgtggtggt agccgttgac gtcgaggacg
     9901 aggagtaggt cccactccca gctggcgccc ctcccttctt gtcggccacg ccgggccctg
     9961 gggaggggcg cctctcttct tcgtagagct gaggtgttca gtgattcacg tgttcgttgg
    10021 cccgacgctg cgccggtcgg aagcgttgct cgccgtgtca gggttgcggg tgcggccgcc
    10081 ggtgcggcac ggggacttgt tcgccgccgc gattggtatc ggtgacaccg tcgtgatcat
    10141 cgacggggtg tatcaccagg ctccggcgct gcgccacaag gagatcctgg ccgcgatggg
    10201 ccgaggcctc cgggtaatcg gggcggcgag catcggcgcg ctacgggctg tcgagctggc
    10261 gccgtacgga atgcttggcg tcggccgcat ctacaccgca tacgcccggg gcgacatcga
    10321 cggcgacgac gaggtcgcgg tcggacaggc ccctgacggg gagtgggatg ctctgacctg
    10381 gccggtggtc aacctccggc acgtcctgga cctggcgcgg tcggcagaga tactcgacgg
    10441 ggagcgggcc gccaggctgc tggaggcgct ccgtgcggtc cactacccgc aacgcacgtg
    10501 ggccgcagtt cgggccgtgt gccgccgcca gggccagacg gcgttcgctg actggctggc
    10561 cgagcagacc gagcgtgacc agtacttcgg cgacctgaag cgcgccgatg ccctcgccgc
    10621 cgtacgtacc gcactcgacg gcttcacgcc gcccggggct gcccggccag caccacactc
    10681 gtgggaatcg ccgtacttcc gtcgctggtc caacgccttc gcccgcaccc gcgttgacgg
    10741 actggacctg tccacggaag accgcctcat ctaccagcag gtgttcgacc ccgatttccg
    10801 agagacatgg acggcctacc tggaacaccg atccctgcgt cccgccgatg ggagccccgg
    10861 cctgccactg aagacgcggt cggcccaggt caccggcggc accctgcccg ctcatcaggt
    10921 gttccacccg acagtggacc tgcgagacga agcaaccgtg gctctgctgc tggctggcga
    10981 ggcatgcgag gaccgcgcgg cggtcgcccg ctacgccgac accctggccg cagttcgccg
    11041 cagccggccc ggattctcga ctgcggcggt gcgcgacgac ctcgctcgcc ggatgttgct
    11101 gcgcgtgtgg cggtgctctg agcatctgtt cgatgaggaa gcctctgccc gcggactggt
    11161 ctgcggggcg cgggcggtgg aggcggcgaa gcggctggtg cctgggtatc tggccgagtc
    11221 tgagcggatg gaggcgacca gtgctgccca gtgacgatct ggttgtcttg ccgggcacga
    11281 tgcgagcccg gccccccgag gagacgtggc agacgctcgc ggggctgttg ccgtcgtacg
    11341 ggatcacccg cgtcgcacgg ctcaccgagt tggactgcat cgggctgccg gtctggaccg
    11401 cgatccggcc ggcgtccatg accctgagca cgtctcaggg caagggcgcg accgatctgc
    11461 tggcgaagtt gtcggccgtg atggaggcga tcgagctgtg gcacgtcgag caaccgctgc
    11521 ctatcgcggt gcgcggctcg gctgtggagg tcgcccctga ctatcccgtc tccgcgctgc
    11581 cgctcatcgt tccgtacccc gaggagactc ttacccggct ggtgtgggag tggacccctg
    11641 gcaccggtct catgagcggt gagaaggtgc tgctgccggt cgccctggtc cgccgccggg
    11701 cgcagcggcc tgagtggagc ccgaatctgc tgcgcgccac cagcaccggc ctggcgtgcg
    11761 gaaacacccg cgacgaggcg ttgctgcacg cactgttcga ggttgttgaa cgggacgttc
    11821 tgttccagga cggacagtgc ggtggccagc ggcggacgct gatcgaccca gcgacagtcg
    11881 atgaccccta cggtcgggag gtgatcgacc ggttgagttc cgccgggatg gcgctggaac
    11941 tgtccctcgt agacggcccg tacgggatcc cggtgtgcct ggcctacctg tggtccgagg
    12001 acttcccggt cgtcttcgcg ggtggcgggt gccacagcag tccggtcatt gcgttgacac
    12061 gggcgttgac cgaggcggcg caatcgcggc tgacggccat cgcgggcacg cgggatgacc
    12121 tcccgagcga tctcgcttgg ttcgacaccc cgccccttag cccggcgcag cgaacagggc
    12181 ttgccgtgtg gccggaggca acaacccact tcgcctcggg cccgggcgac ttcgccgacc
    12241 aggtacgtga cgttgcgcgg cgggtcgaac tcatcaccgg atacgagccg atgaccctgg
    12301 acctgtcgga cgccagggcc cccgtctacg cggtccaggt cgtctgtcct ggcacccggt
    12361 cacggatcag aagggcgatg ccacgatgac gctccactcc gtcaccccag ccgctcccca
    12421 gtctcaacag ctcgcggccc aatacgacgc gctgcacgcc gcgcgggcac gcacgcccct
    12481 ggttgcccgc ctgtacgccg aggcgatggg cgaggactac cccctggagg tcaacgcctc
    12541 cagctcttgt gactggcccc tgctggggct gatgaccgcg cgactgcgga tgcggcccgg
    12601 tcagcttctg gtggacgctg gctgcggcag cggcggcatc gggctgtggc tggcccgcgc
    12661 cctggccacc cgtctggtgg ggttcgacgt ctctcctgtc gccgtcgcgc aggctaccgc
    12721 ccgccgccct ggcttcgtct ctgcagagcg cgcggccttc cgcgttgcgc ggttggaagc
    12781 cagcggcctg cctgacggct gcgcccacgg cgcggtgtgc gtggacgccc tcagcggcgc
    12841 cgccgacaga acagccgcac tgcgcgaact cggccgactc ctggcacccg gcggccggct
    12901 cctcgccacc cgcggcctga ggcccggcgt gacaccaacg tgggagaaac aggcgcgcgc
    12961 cgccgggctg atcctggagt ccgtggacga gcgtcccgcc gagcccgtca tgtgggaacg
    13021 cctctaccgg ctgtggatcg cgcacgccga ggaactgcgg tgcgaactcg gcgacctccc
    13081 cgcgcagaac atgctgattg aggcgcaccg gatgctgccc gtccttcccg gccgccgcgc
    13141 cgtcctgttg accctgcgac gcgccagcac gtcaccgtcc gtgcccgacg cggccggtac
    13201 gatgacccag cccagccgcc cccagggtgg gggatccgtg tccaccgaga ggaccccgca
    13261 gtgagccaga accgccccgc ccgcgcggcg gtgttctcgg ccgggtcctg gggcacggcc
    13321 gtcgccaaga tcctggccga cgccggcacc gacgtcatcg tgcacgcccg ccgcagcgag
    13381 atcgccgacg cgatcaacac gcatcaccgc aaccccggct acttcccgga catcgagctg
    13441 cctgctgccc tgactgcgac gaccgacccg gccaccgcgc tggatggccc ggacttcctg
    13501 gtgctctcca tccccgcgca gaccctgcgg accaacctcg ccgcgtgggc accgcacatc
    13561 ggagatgaca ccgtgatcgt gtcgctgatg aagggcatcg agcagagcag ccacctgcgg
    13621 gccagccaga tcatcaccga ggtgaccggc ctgagcgcgg accgggtcgc cgtgctgtcc
    13681 ggcccgaacc tggcgcgcga gatcatggat ggtcggcctg ccgccgccac cgtcgcctgc
    13741 cccgacgagg acgccgcccg ccgcttccag caggcgtgcc acacccccta cttccggccc
    13801 tacaccagca ccgacgtggc cggatgcgag ctgggcggcg cggtgaagaa cgtcatcgcc
    13861 ctcgcggtcg gcatcgcctc cggcatgggc ctgggagaca acgccacggc catgctcatc
    13921 acccgcggcc tggcggagac cacccggctg gccatggcct tgggcgccca cccggccacc
    13981 ctcgccggcc tgtccggcat gggcgacctg gtggccacct gctcctcccc gctctcccgt
    14041 aaccgcacct tcggaactca cctcggccgg ggcctgagcg tcgagcaggc cgcagccgcc
    14101 acccggcaga ccaccgaggg cgtcaagtcc gcggaggcga tcctcgccct ggcccacgcc
    14161 cacgacatcg agatgccgat cacggaagtg atctccaccc tgctgcacga gaaggtcacc
    14221 ctcgcccagg ctgcggccgc gctgatgcag cggcccccca agcccgagcg ctgaccccct
    14281 ggcgccccgc ctgcgcgggc cgctcctctt caccttcacc ctccccgccc ggaggttcct
    14341 gcccatgcac atgtctgtgc tgtctgctgt ccagatcgcc gtcaccctcg gcttggtggc
    14401 gtggatgatc actggcttca cccgcctgcc cggccgctgg ctgcgctgga agatgttctg
    14461 ccgcgccacc ttcacgatca tctcgctcac cggcaccacc aaggacgggt gcaccgagcc
    14521 cgtgaatgtg tacgactacc tctccccggg gagctttatt ctcggcccgc cccagctcca
    14581 gacgatcctc gaccacctca ccggcagcgg ccggtacgac cggatcgacg gacatggccg
    14641 cgtcctgtcc gctcggggtg agcagcctgt ggaggtgagg gacggccgtg tggttctttg
    14701 acgccttcac ctccggattc cagcacacca ccgacccggg acgcctccag tggttccgga
    14761 tcatcttcgg caccgtgctc accctgcggt tcgccctcgc cttcggccaa ggtggctggg
    14821 accgcttcgc ctccgcctcg ctcagcgccc acctcgccga gcagcgcttc ggcgccgtcc
    14881 gaactcgtct tctggtgacc gtctaccggc ccgccctgat tgtccgtacg gccgccgccc
    14941 tcgctctggc gctaggccct ggcccccgcc tcgcgctgtt ggtggtcctt cccggagccg
    15001 cgatggagct gctgtacctc aagagcccca acgccatccg ctacatcctg ctgaccggca
    15061 cctgcctcct gctcgccgga gacctcggcc acggcctgca cgtcgagcat ggcctgagcg
    15121 aggcgaacac ctgggcgcag tgcctacttg tgctcatcac cacggacatc tactggaaca
    15181 gcgcctggca gaagatccgc tcgcctcagt tccgcaccgg cctctacctc gcccagtgga
    15241 tgcacgtcta cgctcaggtc agggatcaac tgccctacgg cggccagtac gcgatccccg
    15301 gctttgtccg ccgtcacatg ggcaacctgg ctgatcggga cgtccgcctg tggcgactga
    15361 tcgcgaccac ggtcatcgcc atggagatcg cgctgccccc tacgctgctc atcccgcaga
    15421 cgacgcccta tgccgtagtc gccggtgcgg ggatgcacgc cgcgttcacc tgtctcaagc
    15481 cccgccagct cctcaccttc tcaggcctca cagtcggcac ttatctagcc ttcctggcct
    15541 aacacgcgcg ctcggtcccg gtctgcgcat tacctgggag gtaatcgacc tgtcttcagg
    15601 tctccggcac cgtagttgca ccgccccgcc ggtgtcccgc aagacgctgg cggggcgggt
    15661 ctccggccct tcagtcccgg ttctccaccg gacgtgaggg gtcctgactg cttccgctca
    15721 atatttgcgc aggtcacagc tctaccaaga actaaggcaa ttccacggct cggcttatca
    15781 agatccggag ctgatacggc tcgcggctcc ccgggtggcg ctcatctcct gcggcgccga
    15841 caacccctat ggccacccgg caccggcgac cgtcgccgcg ctgcgggcgg gcggggcgct
    15901 ggtgctgcgc accgaccggg acggagagct cgcggtcggc gggacgggcg gggcgggagg
    15961 gaaggtgatg gtgacgaggg actgaggacg cggtgttcgc tcagactggg tccatgaatc
    16021 cgagccaggc cgatgcctat ctccgcagga tccgggccga gcgcccacag cggcccaccg
    16081 gcccggcgct gcgcgagctg catctgcgcc atctgcagac cgtccccttc gagaatctgt
    16141 cgatccactt cggtgaggag atcgtgctgg aggaggagcg gctgctggtc aaggtgaccg
    16201 gacggcggcg aggtggtttc tgctacgaac tgaacggcgc gttcggcgcg ttgctcgccg
    16261 cgctcggcta tgaggtcgag ctgctcgccg gacgcgtcta cggcgacgag ggacggctcg
    16321 gtatcccgta cgaccatctc gccctgcggg tgcggacggt ggagggggac acctggctcg
    16381 cggacgtcgg gttcggggcg cacagccact acccgctggc ctacgcggaa cgcggggagc
    16441 aagccgaccc cggcggggtg ttccgggtgg tggaggccgg gcccgacgcg gccggggtgc
    16501 gcggtggcgg ctcgggcggg gccggggacc tggacgtcgt acggaacggc aggccgcagt
    16561 accggctgga ggcgcggccc cgggtgctcg gggacttcgt ggccgcggcc tggtggcaca
    16621 gcacctcgcc ggtgtcgcac ttcacccggt cgctggtctg ctccagggcc accgaggacg
    16681 gagggagggt cacgctcagc gggcggtcgc tgacgacgac ggacgccgac gggaagcgcg
    16741 ggacacggga gttggggacg gacgaggagg tgctggcggt gtaccgggag cggttcggga
    16801 tcgagctgga ctgtgtgccg actgtgcgaa gccggagttt ttactcataa tccggctcag
    16861 tctccgcaaa tatgctggat ccccttgatg tggggtgtgt tgcctggctg agggctgtac
    16921 gccgtaccag gtgaggtgca gctcgtgctc aagggctgac ctgggggttc ggtgcatgtg
    16981 cggtgccgga gaatggggcc gtgagcgatg tgagacatgt gctggtgctg cccgaccggg
    17041 atgccgccga ggaggcggcc gaggcgctcg gggagcggtt cggcctggac gaggagcccc
    17101 ggctggtccg cgacgcgctg gccggcgagg acgatgccga ggacgcgcag tggctggtgg
    17161 tcctgcggga cgaggacgag cggctggatc cggcggagct ggatgagttc gtgggggagt
    17221 gggacgggtg gcgggaggag ccgtgatcct gccggctgag cagtgaccgg tgtccgggca
    17281 ccgggggagg cgcgactgcc cgcggccaag tgggccccgc agctaggtcg gagcccgcgg
    17341 ctgcgcgagc cctcgcagca gcgtgagccc attgtcagtg gtgcgtggga tgctttgagg
    17401 gatggccagg aagactgcga atgacgaccc tctcgctccg gtgacgcttg ccgtgggcca
    17461 ggaggacctc ctgctcgacc gtgccgtgcg ggaggtggtg gccgccgcca aggccgccga
    17521 cgccgacacg gacgtacgcg acctcacccc ggaccaggtg cagcccggca cgctcgccga
    17581 gctcaccagt ccttcgctct tcgccgagcg gaaagtcgtg gtcgtacgca atgcgcagga
    17641 cctgtccgcc gacacggtca aggacgtgaa ggcgtatgtc ggggcgcccg ccgaggagat
    17701 cacgctcgtg ctgctgcacg cgggcggggc caagggcaag gggctgctgg acgccgcgcg
    17761 caaggcggga gcgcgggagg tggcctgccc gaagatgacc aagcccgcgg accggctggc
    17821 ctttgtgcgg gaggagttcc gctcgttcgg gcggtcggcc gcgcccgagg cgtgccaggc
    17881 gctgtgcgat gccatcggca gcgatctgcg ggagctggcc tcggcggtct cccagctggt
    17941 cgccgacgtg gaggggacga tcgacgaggc ggtcgtcggg cggtactaca cggggcgggc
    18001 ggaggcctcc agcttcacgg tcgccgaccg ggccgtggag gggcgtacgg cggaggcact
    18061 ggaggcgttg cgctggtcgc tggcgaccgg ggtggcgccg gtgatgatca ccagtgcgct
    18121 ggcgcagggc gtgcgggcca tcgggaagtt gtcgtcggct cggggcgggc ggccggctga
    18181 tctggcgcgg gagttgggga tgccgccgtg gaagatcgac cgcgtgcggc agcagatgcg
    18241 ggggtggacg ccggacgggg ttgcggcggc gctcagggct gtcgccgagg ccgatgccgg
    18301 ggtgaagggc gggggcgatg atcctgagta cgccctggag aaggcggttg tgatcatcgc
    18361 tcgggctgcc cggtcccggg ggcgcggata ggtgtccctg ggctccgccc gagaccccgt
    18421 caggggcccc gcccctggat tccggccaca cccacctgcc tcggtccgcc gggaagcttc
    18481 cgtcacggag tcatgggctc ggtcggccgg gaaggcctcc agccagccga caaggccgcc
    18541 ggcgctcagc cccggacccc gctcgcctat ccacccccga atctgtcgct tgaaaagcgg
    18601 cgcacagcat cacaccgccc cataccaaag gccccggcgt ccgccctggg gaagggggag
    18661 cgccgaggcc ttcggttcaa gctgatggac tcgcacccgc gtggcgaacg caggccgcgt
    18721 gcgaatccgg ggtgccggat gggagcggat gagagagggc ccgctctggg tccttccggc
    18781 ggtcagatca aagggagagt tcagcccttg agggacgtga ccttggaagc aagcgccgac
    18841 ttcttgttgg cggcctggtt cttgtggatg acgcccttgg agacggcctt gtcgagcttg
    18901 cgcgaagcct cgcgcaccgc cacggtggcc ttctcgacgt cacccgcggc aacggcctcg
    18961 cgggccttgc ggatcgcggt cttcagggag gacttgacgg ccttgttgcg cagccgagcc
    19021 ttctcgttgg tcttgatccg cttgatctgg gacttgatgt tcgccacgaa ggagcctttt
    19081 caggttctgg ccggggccgc gaaggtcccg taccggtgat ccaaaatttc tctgacgtgc
    19141 ctcgcgctga gagggcatga ggcacagcca tctacagtac cagtggccct gcgagcggcc
    19201 caaaacggtc ctcggtccct ccgcgtggga ccatggagac tacgtatcga tccgacccga
    19261 gaccgttacc tgcggatacc tcaagaatca ggaccctgcg tgcccgcgac ccctaaccat
    19321 gtgcccgagc cgagccgtac cgccccggct ctgatccgca atttctgcat catcgcgcac
    19381 atcgaccacg gcaagtccac gctcgccgac cggatgctcc agctgaccgg tgtggtcgag
    19441 cagcggcaga tgcgtgctca gtacctcgac cggatggaca tcgagcgcga gcgcggcatc
    19501 acgatcaagt cccaggcggt gcgtctgccc tgggccccca ccgagggccc cgaccagggc
    19561 acgactcaca tcctcaacat gatcgacacc ccggggcacg tcgacttcac ctacgaggtc
    19621 tcgcggtcgc tcgccgcctg tgaggggacc atcctcctcg tcgacgccgc ccagggcatc
    19681 gaggcgcaga cgctcgccaa cctctacctg gcgatggaga acgacctcac gatcatcccc
    19741 gtactgaaca agatcgacct gccggccgcc cagccggaga agttcgccga ggagctggcg
    19801 aacctggtcg gctgcgaccc ggaggacgtt ctcaaggtct cggcgaagac cggtctcggc
    19861 gtcgacgcgc tgctgaacaa ggtcgtcaag gagatcccgg ccccggtcgg ggtcgccgac
    19921 gcgcccgccc gcgcgatgat cttcgactcg gtctacgact cctaccgcgg tgtcgtgacg
    19981 tacgtccgtg tcatcgacgg ccagctcaac aagcgcgagc gcatcaggat gatgtccacc
    20041 ggcgccacgc acgagctgct ggagatcggt gtcaactcgc ccgagatgct gccggccgac
    20101 ggcctcggcg tcggcgaggt gggctatctc atcaccggtg tgaaggacgt ccgccagtcc
    20161 aaggtcggtg acaccgtcac cagccagagc aagggggcca cggaggcgct gggcgggtac
    20221 aaggacccga agcccatggt cttctccggc ctgtatccgc tcgacggctc cgactacccg
    20281 gagctgcgcg aggccctcga caagctgcag ctcaacgacg ccgcgctcgt ctacgagccg
    20341 gagacctccg ccgccctcgg cttcggcttc cgcgtcggct tcctcggcct gctgcacctg
    20401 gacgtgatcc gggagcggct ggagcgcgag ttcggcctcg acctgatcgc caccgccccc
    20461 aacgtggtct accgcgtggt catggaggac ggcagcgagc acacggtcac caacccgagc
    20521 gagttccccg agggcaagat caacgaggtc ttcgagccgg tcgtgcgggc caccatcctc
    20581 gcgcccaccg agttcatcgg ctcgatcatg gagctgtgcc agacccggcg cggcaccctg
    20641 ctcggcatgg actacctctc ggaggaccgc gtcgagatcc gctacacgct gccgctcgcg
    20701 gagatcgtct tcgacttctt cgaccagctg aagtccaaga cccgcggcta cgcctcgctg
    20761 gactacgagc ccaccggcga gcagaccagc tccctggtca aggtcgacat cctgctgcac
    20821 ggcgacaagg tggacgcgtt ctccgcgatc acccacaggg accaggcgta cgcgtacggc
    20881 gtacggctcg tcgcgaagct caaggagctg atcccgcggc aggccttcga ggtgccggtg
    20941 caggccgcca tcggctcccg ggtgatcgcc cgcgagacca tccgcgccat ccgcaaggac
    21001 gtcctcgcca agtgctacgg cggtgacatc tcccgtaagc ggaagctgct ggagaagcag
    21061 aaggaaggca agaagcggat gaagatggtg ggttccgtgg aggttccgca ggaagccttc
    21121 atcgccgtgc tgtccagcga tgacagcgcg gggtcggcca aaggcaagaa gtaaccaacg
    21181 gtaacaacgg gtggcgtccg taaaccggac acacaggggc ctgtcgtgtg aaagcgcggc
    21241 aggcccctac gcgtgcgtag cgtcgctctc cgtggaacac gcgaagaaac agacaggccg
    21301 atgcccctta cgcagcggcc ggtcgcggct tactctgatc cctgctcgat agttactcgc
    21361 gagttaaaca acagtgagac agcagcgcga accccccacc gtgagtgaac ccagccgcac
    21421 cgagtacagc cgcaccgtcg cgggcccgga ggatgtcgtg agcgacacac agaccctgat
    21481 cgagaaccgt ccgccgtccg tggcggccct cttcctggaa cgcgtggcgg ccacaccgga
    21541 cgccgaggcc taccgctatc cagtgccgcc agcctcgggc cagggcccgg acgactggaa
    21601 gtcgctcagc tgggcgcagg cggccgggcg ggtgtacgcg atcgcggccg ggctcgtcga
    21661 actgggcgtg cagccggagc agcgggtggc gctcgcctcc tccacccgcg tcgagtggct
    21721 cctcgccgac ctcggcatca tgtgcgccgg cggtgcgacg accaccatct acccgcagac
    21781 caacgaggac gagtcggcct tcatcctctc cgactcggag agccacgtgc tgatcgccga
    21841 ggacgcggcc caggtcgcca aggccgtcga gaagcgcgcc gagctgcccg agctgaccaa
    21901 ggtcgtcgcc atcgacccgg ccggcgtgga gacgaacgac tgggtgacca ccctcgccga
    21961 gctggagcag cgcggcgccg cctacctgga gaagcacccc gagctgatca aggagcgggt
    22021 cggcgcgatc acccgggagc agctcgccac cctcatctac acctccggca ccaccggccg
    22081 ccccaagggc gtgcgcctgc cgcacgacaa ctgggcgtac atggcgaagg cgatcgccgc
    22141 gaccggcctg atcaccgccg aggacgtgca gtacctgtgg ctgccgctcg cgcacgtctt
    22201 cggcaaggtc ctcacctccg ggcagatcga ggtcgggcac gtcaccgccg tcgacggccg
    22261 cgtcgacaag atcatcgaga accttccggt ggtgcagccg acgtacatgg ccgccgtgcc
    22321 gcgcatcttc gagaaggtct acaacggcgt cgccgccaag gcccgcgagg gcggcccggc
    22381 caagtacaa
//
