LOCUS       NZ_CM002285            32709 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6225048
            Orig. end                         :: 6257757
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32709
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /product="terpene-precursor"
                     /region_number="31"
                     /rules="IucA_IucC"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..32709
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="neighbouring"
                     /product="NI-siderophore"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..29770
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29770
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15770](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..15770)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            241..606
                     /locus_tag="M878_RS76525"
                     /old_locus_tag="M878_28970"
     CDS             241..606
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS76525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_28970"
                     /product="hypothetical protein"
                     /protein_id="WP_158692782.1"
                     /transl_table=11
                     /translation="MTSVLLPSAQSLVTAILTDGWTHVRDALARRWSRQTGEARADVER
                     RLDTAHRQAAGMGDDEAVQRAYWAGYLAAVLAERPAMLDVVRELPDMPDLHNTNNGTVT
                     NLIQARDVHGNISFGPQ"
     misc_feature    complement(936..953)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            993..1301
                     /locus_tag="M878_RS76535"
                     /old_locus_tag="M878_28980"
     CDS             993..1301
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="M878_RS76535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_28980"
                     /product="transposase"
                     /protein_id="WP_023550442.1"
                     /transl_table=11
                     /translation="MESMGKKKPRPRRSFTPECKAEIVELCRRGDRSVGQVAKDFDLTE
                     TAVRDWVKQAEVDAGERDGLTRSECEELAQLRRENCRLREDVEILKRATAFFAKETR"
     gene            1298..2170
                     /locus_tag="M878_RS76540"
                     /old_locus_tag="M878_28985"
     CDS             1298..2170
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /locus_tag="M878_RS76540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_28985"
                     /product="IS3 family transposase"
                     /protein_id="WP_023550444.1"
                     /transl_table=11
                     /translation="MTVHPFIEAEKQAGHSVKRACELLKVSRAAFYARRTGAVGPRAVQ
                     DAELTERMTAVHDRSRGTYGAPRIHAALKREGTACGRRRIARLMRAAGLAGRHRRRRHR
                     TTIADPHAATRPDLVLRDFRPDPTTADVRWCGDITYIPTDEGWLYLATVIDIASRRVVG
                     WATADHLRTELVAEALRSACHRRRPAGSVIFHSDRGCQYTSHEFALLAAELDIRLSVGR
                     TGQCWDNALAESFFATLKNELYGDRPWPSRSVARTAVFEWIEGWYNLHRLHSSLGYRSP
                     ADYEAALAA"
     gene            complement(2146..2883)
                     /locus_tag="M878_RS76545"
                     /old_locus_tag="M878_28990"
     CDS             complement(2146..2883)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS76545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_28990"
                     /product="hypothetical protein"
                     /protein_id="WP_023550446.1"
                     /transl_table=11
                     /translation="MATIRNRIRKDGTASFQVRWLQGGRGGSWESERFGELAEAEAFKK
                     LVDAHGQQWPFGWVPSQGFVEPEQDPDDVPLAEWSRRYLERLTGIDSRTRDDYLREVDR
                     HLSLFVHTTRAGQLMPATIGNITSDDVHDWIRLQEAGQQDPVTGRWIRRPAAPKSIANR
                     HGLLWCIVQAAIEAEPPLRTKNCCAGTRLPRADDEIVEEMVFLEHDEYQLIRRCVTDED
                     ARVSLFRFDGHRRCGGQAARAAS"
     tRNA            complement(2997..3069)
                     /anticodon=(pos:complement(6228082..6228084),aa:His,
                     seq:gtg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="M878_RS76550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="M878_28995"
                     /product="tRNA-His"
     gene            complement(2997..3069)
                     /locus_tag="M878_RS76550"
                     /old_locus_tag="M878_28995"
     misc_feature    3082..3096
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.67"
                     /tool="antismash"
     gene            complement(3194..3796)
                     /gene="orn"
                     /locus_tag="M878_RS76555"
                     /old_locus_tag="M878_29000"
     CDS             complement(3194..3796)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="orn"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131557.1"
                     /locus_tag="M878_RS76555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29000"
                     /product="oligoribonuclease"
                     /protein_id="WP_031225907.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLSDDALIEVAALVTDSELNVLGEGVDIVI
                     RPPDQALETMPEVVRQMHTASGLLAELPNGTTLKDAEEQVLAYVKQYVKEPGKAPLCGN
                     SVGTDRGFLERDMPALESHLHYRIVDVSSIKELARRWYPRAYFNSPEKNGNHRALADIR
                     ESIAELRYYREAIFVPQPGPDSDTAKAIAAKHVLPAQ"
     gene            complement(3940..5151)
                     /locus_tag="M878_RS76560"
                     /old_locus_tag="M878_29005"
     CDS             complement(3940..5151)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009188750.1"
                     /locus_tag="M878_RS76560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29005"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_023550450.1"
                     /transl_table=11
                     /translation="MSHDSTAAPEAAARKLSGRRRKEIVAVLLFSGGPIFESSIPLSVF
                     GIDRQDAGVPRYRLLVCAGEEGPLRTTGGLELTAPHGLEAISRAGTVVVPAWRSITAPP
                     PEEALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVD
                     PRELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGNEAAGALARRLVVPPRRTGGQERYLD
                     RSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWL
                     ITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQ
                     GDRPADAEPALPAPGPPPGLPGPGAIGHSPTMLHPDRDNGVPMQTRRQAAGAVGLLPGP
                     RSGS"
     misc_feature    complement(4477..4479)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5302..5322
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(5339..5352)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.26"
                     /tool="antismash"
     misc_feature    complement(5491..5505)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.16"
                     /tool="antismash"
     misc_feature    5500..5513
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.94"
                     /tool="antismash"
     gene            complement(5530..5820)
                     /locus_tag="M878_RS76565"
                     /old_locus_tag="M878_29010"
     CDS             complement(5530..5820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016326293.1"
                     /locus_tag="M878_RS76565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29010"
                     /product="hypothetical protein"
                     /protein_id="WP_023550451.1"
                     /transl_table=11
                     /translation="MPGPRSTSEPPSAPDTVSDVIRWAAFSCVLVPVVLVWYGSSLAGA
                     AGAALGLAAVTAACRILLRRSERCAERHACRAKRCAVQRGGRHTRRRTPVD"
     misc_feature    5855..5870
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.64"
                     /tool="antismash"
     misc_feature    complement(5867..5882)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            6148..6675
                     /locus_tag="M878_RS76570"
                     /old_locus_tag="M878_29015"
     CDS             6148..6675
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325548.1"
                     /locus_tag="M878_RS76570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29015"
                     /product="universal stress protein"
                     /protein_id="WP_023550453.1"
                     /transl_table=11
                     /translation="MAGHEFFEPADRKRPVADPTAADPLAAEESRPSCDPAFRHGVVVG
                     FDGSTSSERALAYAIGMAHRSRSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLG
                     LELACADYLAEVPWILVERGGDICHELEEVGREYEADAIVVGSTHGIVGRIFGSVAGRL
                     AKRAQRPVIVIP"
     gene            6803..7345
                     /locus_tag="M878_RS76575"
                     /old_locus_tag="M878_29020"
     CDS             6803..7345
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047887.1"
                     /locus_tag="M878_RS76575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29020"
                     /product="GPR1/FUN34/YaaH family transporter"
                     /protein_id="WP_031225909.1"
                     /transl_table=11
                     /translation="MDNGSTTVVGRLALGITLLAFGLGTTGVIHGVAASDAVSVAHYVG
                     GVALFLVGLLAFRGGDGVSGTGFAALGALWFTWAVGGHSSANAAGLFLLLFALVALTLT
                     LAGGDSLGQVMHGLLFLAMLVLAVAAFADSSSLSKVGGWVAAVSGAVAWYAATASLAHW
                     PTALPGRAARRGVTATG"
     gene            complement(7492..9309)
                     /gene="glmS"
                     /locus_tag="M878_RS76580"
                     /old_locus_tag="M878_29025"
     CDS             complement(7492..9309)
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:0006040 - amino sugar metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980526.1"
                     /locus_tag="M878_RS76580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29025"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_023550457.1"
                     /sec_met_domain="GATase_7 (E-value: 1e-15, bitscore: 56.7,
                     seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGIVVTSPKAPGLK
                     MVKAKGRVRDLEVKVPARFKGTTGIAHTRWATHGAPSDVNAHPHMSADSKVAVVHNGII
                     DNAADLRRKLEADGVEFLSETDTEVLTHLIARSTAEKLEDKVRQAVRVIEGTYGIAVLH
                     ADFPDRIVVARNGSPVVLGIGEKEMFVASDIAALVMHTRQIVTLDDGEMATLKADDFRT
                     YTTEGTRTTAEPTTVEWEAESYDMGGHDTYMHKEIFEQADAVDRVLRGRIDDRFSTVHL
                     GGLNLDAREARQIRRVKILGCGTSYHAGMIGAQMIEELARIPADAEPASEFRYRNAVVD
                     PDTLYVAVSQSGETYDVLAAVQELKRKGAKVFGVVNVVGSAIAREADAGIYVHAGPEVC
                     VVSTKCFTNMTVAFALLALHLGRTRDLSVRDGKRIIEGLRKLPEQITEILKQEEKIKEL
                     AELYADARSMLFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEPALPT
                     VAIVPDDDLLEKNRAALEEIKARSGKILAVAHQHQDKADQTIVVPKNEDELDPILMGIP
                     LQLLAYHTAKALGRDIDKPRNLAKSVTVE"
     misc_feature    9287..9301
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.45"
                     /tool="antismash"
     gene            complement(9329..9586)
                     /locus_tag="M878_RS76585"
                     /old_locus_tag="M878_29030"
     CDS             complement(9329..9586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131788.1"
                     /locus_tag="M878_RS76585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29030"
                     /product="hypothetical protein"
                     /protein_id="WP_023550459.1"
                     /transl_table=11
                     /translation="MHDELVDHLTRSTPLNRGEALRVVQDVLAFFDEPTEDYVRRRHRE
                     LQTQGLVNAEIFERIGADLKYRAVAPPELTLRQLRRIVYG"
     gene            9764..11329
                     /locus_tag="M878_RS76590"
                     /pseudo=""
     CDS             9764..11329
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016434993.1"
                     /locus_tag="M878_RS76590"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="metallophosphoesterase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGVPEKLAERMSMAEQHEYLRARFSRRTMIRGGAVTLGAVVGGAF
                     VPGATAQAAVPTQATAPAAETVDGALVAPFGRHLAYGNDPRTEMTVSWQVPVAVKNPFI
                     RIGAHPWDLSRKIEAEVRSLYTPAGVGASGDHTQYYLHAQLTHLRPGRTYYYGVGHEGF
                     DPAERHLLGTLGTFTTAPAHKAPFTFTAFGDEGVGYHGLANNALILGQNPAFHLHAGDI
                     A"
     cand_cluster    11348..32709
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    11348..32709
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[21347:22709](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      21348..22709
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
     gene            complement(11357..12229)
                     /locus_tag="M878_RS76595"
                     /old_locus_tag="M878_29045"
     CDS             complement(11357..12229)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976013.1"
                     /locus_tag="M878_RS76595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29045"
                     /product="DUF4429 domain-containing protein"
                     /protein_id="WP_023550465.1"
                     /transl_table=11
                     /translation="MAEIIQKDGTWAFDGDALRLTPGRDKNVSLLRRELGELVVPLGAL
                     AGVSFEQGRKSGRLRLRLRDGADPLTQATGGRLAEPNDPYQLTVESDRYGVAEYFADEV
                     RNALLLDGVSPEPVTEYLLPGPALPVSASAGDGTAGFDGERVRLEWNWKTEDAKSAGGP
                     RTIPLADVVGVAWQPAAGLENGHLRFLVSGAPVTAPPKYDPNAVELWGFKRDPLMALVA
                     AAVQARLPHPAAAEAHAPKEPPVLDKAPAGDDHDALLRRLRELGELHRDGVLTEEEFTL
                     AKQAVLKRM"
     misc_feature    complement(12260..12275)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.29"
                     /tool="antismash"
     gene            12341..13942
                     /locus_tag="M878_RS76600"
                     /old_locus_tag="M878_29050"
     CDS             12341..13942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986672.1"
                     /locus_tag="M878_RS76600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29050"
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="WP_023550467.1"
                     /transl_table=11
                     /translation="MRRNHSTTPRTPGILGSLLLVAAAGVFTLGAAPAARAAAPAPLGQ
                     VVPAPASVAPGGAPYRITRGTGVRVDDSAEVRRIGSYLTGVLRPSTGYPLPLTDHGSGG
                     IRLHLAQGDFGAEGYRLHSDAAGVTVTASAPAGLFHGVQTLRQLLPAAVEKRTAQPGPW
                     QIAGGTIEDRPRYSYRGAMLDVSRHFFTVAQVKRYIDQLALYKINELHLHLSDDQGWRI
                     AIDSWPRLADYGGSTEVGGGKGGYYTKAEYRQIVSYAASRYLEVVPEIDMPGHSNAALA
                     SYARLNCNGQAPSLYTGTEVGFSSLCVPKQATYDFVNDVVRELAAITPGRYLHIGGDEA
                     HSTSHTDYVTFMDRVQPIVAKYGKTVIGWHQLTGAHPAKGAIAQYWGLDSTSAADKAQV
                     AKAAQNGTGLILSPADRIYLDMKYTKDTKLGLDWAGLVEVQRSYDWNPGAYLPGAPAAA
                     IRGVEAPLWSETLKTNADIDYMAFPRLPGAAELGWSPAATHDWDAYKVRLAAQAPRWAA
                     LGIDYYRSPQVPWPAS"
     gene            complement(14001..15770)
                     /locus_tag="M878_RS76605"
                     /old_locus_tag="M878_29055"
     CDS             complement(14001..15770)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672889.1"
                     /locus_tag="M878_RS76605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29055"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_023550469.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.2e-77, bitscore:
                     259.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLADAVAHLSPERWATANRLLIRKALAEFAHERLITPEQEGEQY
                     VVRGDDGLTAYRFSAVRRALDHWQIDADTLTRHREGAELPLSSLDFFIELKDSLGLSDE
                     ILPVYLEEISSTLSGTCYKLTKPRVTSAELAGGGFQAIETGMTEGHPCFVANNGRLGFG
                     IHEYLAYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFLREELGEPTLTRFHATLTD
                     QGLAPADYLLIPVHPWQWWNKLSVTFAAEVARRHLVCLGEGDDEYLAQQSIRTFFNTSD
                     PHKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLAQLIENDPVLKSTGLTIIRERAA
                     VGYRHLEYEQATDRYSPYRKMLAALWRESPVSGLREGESLATMASLLHVDHEGASFAGA
                     LIERSGLTPTEWLRQYLRAYYTPLLHSFYAYDLAFMPHGENVILALKDGAVQRAIYKDI
                     AEEIVVMDPDAVLPPEVARIRADVPEDRKLLSIFTDVFDCFFRFLAAHLATEGILAEDA
                     FWRTVAEVTREYQDANPELAHKFRQYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGAL
                     QLVGTLKNPIAGF"
     gene            complement(15767..16297)
                     /locus_tag="M878_RS76610"
                     /old_locus_tag="M878_29060"
     CDS             complement(15767..16297)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065771.1"
                     /locus_tag="M878_RS76610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29060"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_023550471.1"
                     /transl_table=11
                     /translation="MTFTFRDVDPLQDAELLHSWVTHPKASFWMMQDAKLENVERAYME
                     IAADAHHHALLGLRGGEPAFLMEKYDPAHRELVGLYEAQPGDIGMHFLTPATDTPVHGF
                     TRSVITAVMARLFEDPATLRVVVEPDVRNKAVHALNEAVGFVPEREIRKPEKKALLSFC
                     TREQFAAATGVAA"
     gene            complement(16294..17580)
                     /locus_tag="M878_RS76615"
                     /old_locus_tag="M878_29065"
     CDS             complement(16294..17580)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004987747.1"
                     /locus_tag="M878_RS76615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29065"
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_031225911.1"
                     /transl_table=11
                     /translation="MTALPEASRTHDFVGIGLGPFNLGLACLTEPIDGLDGVFLDSKPD
                     FEWHAGMFLDGAHLQTPFMSDLVTLADPTSPYSFLNYLKEKGRLYSFYIRENFYPLRVE
                     YDDYCRWAAGKLGSVRFGTTVTEVTYEDERYVVRTERGETFRGRHLVLGTGTVPFVPQA
                     CRDLGGDFVHNSQYMHRKAELQSKKSITIVGSGQSAAEIYYELLAEIDSYGYQLNWVTR
                     SPRFFPLEYTKLTLEMTSPDYIDYFRALPEETRYRLEKQQKGLFKGINSDLIDSIFDLL
                     YQKNVTSGDRPVPTRLLTNSSLTSARYDADGGYTLGFHQDEQDKDFEIGTEGLLLATGY
                     HYEPPAFLAPIRDRLLFDGHGRFDVARNYAVDVTGRGVFLQNAGVHTHSITSPDLGMGA
                     YRNSYIIRELLGTEYYPVEKTIAFQEFSA"
     gene            complement(17564..19006)
                     /gene="desA"
                     /locus_tag="M878_RS76620"
                     /old_locus_tag="M878_29070"
     CDS             complement(17564..19006)
                     /EC_number="4.1.1.18"
                     /NRPS_PKS="Domain: Aminotran_5 (140-265). E-value: 1.8e-10.
                     Score: 32.2. Matches aSDomain:
                     nrpspksdomains_M878_RS76620_Aminotran_5.1"
                     /codon_start=1
                     /gene="desA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_099499428.1"
                     /locus_tag="M878_RS76620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29070"
                     /product="lysine decarboxylase DesA"
                     /protein_id="WP_023550474.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2e-05, bitscore:
                     22.9, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 3e-07, bitscore:
                     28.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSHLLNGLTAEHYRSSVTEGVERVAAKLATTDRPFTGVTVDALT
                     PRVDAIDLDRPLGDTAAVLDELEDVYLKDAVYFHHPRYLAHLNCPVVIPAVLGEAVLSA
                     VNSSLDTWDQSAGGTLIERKLIDWTATRIGLGPAADGVFTSGGTQSNLQALLLAREEAK
                     TDSLAGLRIFASEVSHFSVKKSAKLLGLGQEAVVPLPVDHDKRLQTVALARELERCRRD
                     GLVPMAVVATAGTTDFGSIDPLPEIAELCAQYGVWMHVDAAYGCGLLASLKYRARLAGI
                     ERADSVTVDYHKSFFQPVSSSALLVRDTATLRHATYHAEYLNPRRMVQERIPNQVDKSL
                     QTTRRFDALKLWMTLRVMGADGIGALFDEVCDLAAEGWELLAADPRFDVVVEPTLSTLV
                     FRYIPAAVTDPAEIDRANLYARKALFASGDAVVAGTKVGGRHYLKFTLLNPETTAADIA
                     AVLDLIAGHAEQYLGESLDRAS"
     aSDomain        complement(18212..18586)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS76620_Aminotran_5.1"
                     /evalue="1.80E-10"
                     /label="M878_RS76620_Aminotran_5.1"
                     /locus_tag="M878_RS76620"
                     /protein_end="265"
                     /protein_start="140"
                     /score="32.2"
                     /tool="antismash"
                     /translation="GVFTSGGTQSNLQALLLAREEAKTDSLAGLRIFASEVSHFSVKKS
                     AKLLGLGQEAVVPLPVDHDKRLQTVALARELERCRRDGLVPMAVVATAGTTDFGSIDPL
                     PEIAELCAQYGVWMHVDAAYG"
     misc_feature    19078..19096
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.99"
                     /tool="antismash"
     misc_feature    complement(19083..19101)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 34.36"
                     /tool="antismash"
     misc_feature    complement(19085..19105)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.37"
                     /tool="antismash"
     misc_feature    complement(19101..19115)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.23"
                     /tool="antismash"
     misc_feature    complement(19129..19144)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            complement(19157..19990)
                     /locus_tag="M878_RS76625"
                     /old_locus_tag="M878_29075"
     CDS             complement(19157..19990)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672885.1"
                     /locus_tag="M878_RS76625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29075"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_023550476.1"
                     /transl_table=11
                     /translation="MTTAVAAPFRFFALQVIRTRRLGPSLVRVTFGGAELEAFHSDGRD
                     QSLSLFLPHPGQPEPVVPLELGDGWWQGWRELPDDVRAVMRSYTLRALRRDALGHTTEI
                     DIDFALHTPAGPASRWASRAAAGDRVLLLGPAIADNRAIRFRPPEDTDLVVLWGDETAV
                     PAATAILESLPAGIRARAWLEVPHAGDIQDVRTDADAEITWLVRHDGAPMAVDAVRAAR
                     LPLSERPYVWIAGESGQVKALRRYFAGERGVDRRRVTFVGYWRQGMTEEQLRATE"
     gene            complement(20042..21088)
                     /locus_tag="M878_RS76630"
                     /old_locus_tag="M878_29080"
     CDS             complement(20042..21088)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435001.1"
                     /locus_tag="M878_RS76630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29080"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_023550478.1"
                     /transl_table=11
                     /translation="MSQARATHLTRRGLLVAGGAVGLGAALAACGDDKGKDSDAGSGTK
                     AAKSGPWSFKDDRGTTVKLDKVPADIVAFTGVGAALFDYGVQVKGVFGPTKTSAGKPDV
                     QAGDMDISKVTILGNTWGQFNIEKYAALAPDVLITTMFDNAGTLWYVPEESKKKIAQLA
                     PSVGISAYDRQLTEPLQRVWDLAESLGADMKAAKVTDAKKRFEAAAARLRAAAKAKPDL
                     KVMAGSASDQLFYVSGTHLSVDLEYFKALGVNFVEPPESAKKQGGGWFESLSWENVDKY
                     QADIIMMDDRSSAIQPAGISKPTWKKLPAVKAGQVISRSPEPILSYDKCVPLLTSLAEA
                     LEKAKKVS"
     misc_feature    complement(21140..21158)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.94"
                     /tool="antismash"
     gene            21348..22709
                     /locus_tag="M878_RS93020"
                     /old_locus_tag="M878_29085"
     CDS             21348..22709
                     /EC_number="4.2.3.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376596.1"
                     /locus_tag="M878_RS93020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29085"
                     /product="class 1 isoprenoid biosynthesis enzyme"
                     /protein_id="WP_245238214.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.7e-27, bitscore:
                     94.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGDVSAVEDVVRADAALLEEDLARFLGSLTGRPPGAPGHGSAYA
                     AALDRALHLPVADALGSKAGQEALRPHPGAPGGGAPLRPSMVYWAYRNYRGFGDISDAS
                     AESGAYAVPGASVVRGASAVPDASVMRGASVVPDASAVPDASTVSDVSAEPDALAPPHA
                     SDVPDAPLASAGDGAALATLAAVRRAAVAVRVLLKAAVALDDIQDGSTVRYGEPALHLT
                     HGVPLALNTGSWLITAALAHAADPAVVESLLAAVANGFTGQAVDLATRSDRTRAELTEA
                     PCAERIGFWESMAALKTGTLFRMPLDAALAALRADAAERAALDEAMRQLGLASQLFNDV
                     ADFVPELGGTNTHEDLDALSNRVLLELLDSAPPDIRRDPSGERIRGYALGHPGLDRTLL
                     ALAAEAVERKRAAKEAVHRVCRSAESAAYFDITIERKGHLVDRLHDTLRQRSGV"
     gene            22706..23350
                     /locus_tag="M878_RS76640"
                     /old_locus_tag="M878_29090"
     CDS             22706..23350
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376619.1"
                     /locus_tag="M878_RS76640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29090"
                     /product="biliverdin-producing heme oxygenase"
                     /protein_id="WP_023550482.1"
                     /transl_table=11
                     /translation="MTATAADCLRTGTRAWHDALETTGFATALLAGTLPLDRYMAQLTA
                     YRVVLRTLETELSRTAEPAVAGLWTAEDLRKVPLIERDLRHFAVRGASPVRWPAAAAVA
                     FAGEIRTTAVAEPLSLLGFLYVLEGSTLGARYLSRYVTDAYGLHGTDGTAYYTSGDRAR
                     WTRFTTRLDEALTDPATQTRALATADRAYHHTTRITEALSSGLPPRQRCAP"
     gene            complement(23659..>24546)
                     /locus_tag="M878_RS76645"
                     /old_locus_tag="M878_29095"
                     /pseudo=""
     CDS             complement(23659..>24546)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.4"
                     /locus_tag="M878_RS76645"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29095"
                     /product="methyltransferase domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="PCMT (E-value: 1.9e-24, bitscore: 85.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TDDVLVTQMTEGAATSSSTAPGLMLVMLHALDVTEGASVLEVATG
                     TGYNAALLAARLGSANVTSIEVDPELTKLAEARLRACGYTPTVLTGDGRAGHSAGAPYD
                     RLIATCGFARLPYAWVEQVRPGGVIVSPLGWGTARLTVGGDGTASGRFLVTPSYFMSVR
                     SIGETGAAPYPGDPQDPDERTTHLEASMPFRDDAFPFLLSLVVPGTAQASDLDNDRRVI
                     GCRLWAADGSWARVEGASVRQSGPRRLWDGVEAAWRWWEEQERPSRDRFGLTVNREGQR
                     VWLDSAEHLVPVVG"
     gene            complement(24604..24753)
                     /locus_tag="M878_RS98990"
                     /old_locus_tag="M878_29100"
     CDS             complement(24604..24753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS98990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_29100"
                     /product="hypothetical protein"
                     /protein_id="WP_023550486.1"
                     /transl_table=11
                     /translation="MTVTTSDTDEARRLRRDLAAALAEKGDLTDPVWRKVFEEVPRHVF
                     VPEF"
     gene            complement(24750..25730)
                     /gene="tgmB"
                     /locus_tag="M878_RS76650"
                     /old_locus_tag="M878_29105"
     CDS             complement(24750..25730)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tgmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379405.1"
                     /locus_tag="M878_RS76650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29105"
                     /product="ATP-grasp ribosomal peptide maturase"
                     /protein_id="WP_031225913.1"
                     /transl_table=11
                     /translation="MTQRLPSDAVLVVTEEMDPTADLVVDELTRRKVPVMRFDMGDFPQ
                     RMTLTAEHDAAPWSGVLTDIYRSVRLEEVRAVYYRRPRLPAVSSTIPEPHRTWADDQAL
                     AGLLGTLYALPVLWVNRPEIDGVASHKPGQLPIAAALGLRTPRSLISTDPGAARAFCKS
                     IGGPVICKPLMGSPLRYDDGRRNGVPTHLIDPAEIDDSASLTAHLFQEWIDKAHEVRLT
                     VVGHRLFAAEIHAGSDAARIDWRSDYDALTYKPCTVPEPVRRGVLGWLDRFNLNFGAFD
                     FAVTPQGDWVLFECNPSGEWSWIQNSTGLPIAAALAELLAEGKTS"
     gene            complement(25738..25953)
                     /gene="tgmA"
                     /locus_tag="M878_RS76655"
                     /old_locus_tag="M878_29110"
     CDS             complement(25738..25953)
                     /codon_start=1
                     /gene="tgmA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379420.1"
                     /locus_tag="M878_RS76655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29110"
                     /product="putative ATP-grasp-modified RiPP"
                     /protein_id="WP_023550489.1"
                     /transl_table=11
                     /translation="MTTATIPFGARAERQPYTIDVDGSTFAYDHQRQVNVMSDGTLLAH
                     STLRASCTNTNWDSKNDDTSDPYVIR"
     misc_feature    complement(26137..26152)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     gene            complement(26243..26449)
                     /locus_tag="M878_RS98995"
                     /old_locus_tag="M878_29115"
     CDS             complement(26243..26449)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121826.1"
                     /locus_tag="M878_RS98995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29115"
                     /product="hypothetical protein"
                     /protein_id="WP_037730889.1"
                     /transl_table=11
                     /translation="MKRPQGTGKGADTPWLSAECALALRPGYEDLHDACHQTADVPLPG
                     SLGLLLMRRCPCACHAPVAGGAR"
     gene            26942..28396
                     /locus_tag="M878_RS76670"
                     /old_locus_tag="M878_29125"
     CDS             26942..28396
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953412.1"
                     /locus_tag="M878_RS76670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29125"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_023550495.1"
                     /transl_table=11
                     /translation="MDDTTPGPLAPGVLDRGDLKRALAEHDFAAAFALIKKWGGLSQNR
                     IAAACQLTPGKVSTIISGRQQVTSFEVICRIADGLRIPGRMVGLADRPWEAQPDIPDQP
                     TPTPATRLPVEDESWIPTATVHLTGDLTRSDLLMDRRAATCAIAGAALSGAALLDSLEG
                     WLQPASASGSGTYHRGRIGMGEVRQLEGTARAFRAWDHRYGGGLRRKAVVGQLNEVAGH
                     LEEHQAPDVERGLFQVMAYLGGTAATIAWDSGLQRQAQSYYLLALRAAHAAGDAAFGAN
                     VLAGMARQMLYRDRPPDALELVHLAQKGARRAAGPRLRAMLHTREAWAYAAMGRAAAFQ
                     RATGEAAEALADAGADDEPYWISYFDNAELSGVTGGRLLDMARKEPQQYAERAADSIRQ
                     ALARRGPEAGRSHALDRIGLAECHFLMGDVTGAVEHTQRAVEAAARTKSSRVRAQLGQL
                     YPYTVGRGASRPTAEARTMIRDMLSS"
     misc_feature    27275..27277
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            28406..28891
                     /locus_tag="M878_RS76675"
                     /old_locus_tag="M878_29130"
     CDS             28406..28891
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967718.1"
                     /locus_tag="M878_RS76675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29130"
                     /product="hypothetical protein"
                     /protein_id="WP_023550497.1"
                     /transl_table=11
                     /translation="MTTIAVTGHMDLTEDSVPLVLDALRETLKPYAADLTGVTCIAKGA
                     DSLFAEVVLELGGRLTAVIPSRDYRRNKVKTDHADTFDRLSEAAGEVLVLEHETANRSA
                     YEDANRTLLQRADRLVAVWDGTPPSAKGGGTADTVLEARDAGLPVDVIWPDGAARRG"
     gene            complement(<28934..>29157)
                     /locus_tag="M878_RS94900"
                     /pseudo=""
     CDS             complement(<28934..29157)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325537.1"
                     /locus_tag="M878_RS94900"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVRVPAANLLGEEGRGYARFLRIRDEGRIAIAALETGL"
     gene            29165..29659
                     /locus_tag="M878_RS76680"
                     /old_locus_tag="M878_29145"
     CDS             29165..29659
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS76680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_29145"
                     /product="hypothetical protein"
                     /protein_id="WP_023550502.1"
                     /transl_table=11
                     /translation="MLLALSEEYTDHYTDHYTVDGDIFDECTDIALTAFLSLAERGDGE
                     CGQAWQNWVTREGRETYAYMTLDALLAAMAVHSTEAAQDDRTVLVPVRVTDVLRRDRAY
                     YNRYLRRALPNPLRDAKQLVLFSNIPITDSRALGEAMHCLQQWCSKGSLARVYSAINSG
                     G"
     misc_feature    29489..29491
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            29656..30240
                     /gene="cyaB"
                     /locus_tag="M878_RS76685"
                     /old_locus_tag="M878_29150"
     CDS             29656..30240
                     /codon_start=1
                     /gene="cyaB"
                     /inference="COORDINATES: protein motif:HMM:NF014038.4"
                     /locus_tag="M878_RS76685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29150"
                     /product="class IV adenylate cyclase"
                     /protein_id="WP_031225916.1"
                     /transl_table=11
                     /translation="MTRLDSAIEVERKRQLPDDGRQLALLLGELGWKPTHPLTEVDTYY
                     SRPDIDYMATVECLRVRRRGDFAEITYKPPSTAVTHSANGVISKQETNVHLDSASQAAL
                     ADQLLEYIGMRPLVRVEKNRTTYHHPTQPGVTVSIDMVAGVGAFVETEVISTDVTLATL
                     KVEQTENQLGITDLPPVDLPYRDLALTRAPA"
     gene            complement(30350..30766)
                     /locus_tag="M878_RS76690"
                     /old_locus_tag="M878_29155"
     CDS             complement(30350..30766)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS76690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_29155"
                     /product="hypothetical protein"
                     /protein_id="WP_158692783.1"
                     /transl_table=11
                     /translation="MKAAKYATGLTLGLMVTATLVTPAASAAPHSARADRLVLTNSDNG
                     RTVARSVGDDTEIRLKASRERGLTYTWSMPSTRDAHVLARTVSGTTPAGDAYAVLHAES
                     PGTSTVSAVRQCHPDPGYKCPLAIAPWKATIKVS"
     gene            complement(30877..32037)
                     /locus_tag="M878_RS76695"
                     /old_locus_tag="M878_29160"
     CDS             complement(30877..32037)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565684.1"
                     /locus_tag="M878_RS76695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_29160"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_031225918.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.7e-36, bitscore:
                     123.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9.7e-22, bitscore:
                     76.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.4e-49, bitscore:
                     165.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHRLSPELEELRRTVEEFAHDVVAPKIGDFYERHEFPYEIVREM
                     GRMGLFGLPFPEEYGGMGGDYLALGVALEELARVDSSVAITLEAGVSLGAMPLHLFGTE
                     EQKREWLPRLCTGEILGAFGLTEPDGGSDAGATRTTARLDPDTNEWVINGTKCFITNSG
                     TDITGLVTVTAVTGRKPDGRPEISSIIVPSGTPGFTVAAPYSKVGWNASDTRELSFADV
                     RVPAANLLGEEGRGYAQFLRILDEGRIAIAALATGLAQGCVDESLKYAKERHAFGKPIG
                     ANQAIQFKIADMEMKAYTARLAWRDAASRLVAGEPFKKEAALAKLYSSTIAVDNARDAT
                     QIHGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGLVS"
     misc_feature    32116..32131
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.16"
                     /tool="antismash"
ORIGIN
        1 agagaccacc agttcgggcc cgggcggcat cgcagccagc acctcatccg cggcagcccc
       61 accctgcgaa gcagcgcaca cgtacgcgac cggggcgtgg ccggctgcct cgcacgccgc
      121 agccaagtcc tcgaagccct cggccccgta cgacatcagc actacgcgca tccgtcagcc
      181 accttccacc acgacgggcg aagccgaacc gcaaaggtgc gtgatcatct catggatccg
      241 atgacatccg tgctcctgcc cagcgcacag tcccttgtca cggcgattct taccgacggc
      301 tggacacacg tacgcgacgc cctggcgcgc cgctggagcc ggcagaccgg cgaagcgcga
      361 gccgacgttg aacgccgtct ggacacggcc caccgccaag ccgcaggcat gggcgatgac
      421 gaggccgtcc agagagcgta ctgggccgga tatctcgccg ctgttctggc cgagcgccca
      481 gccatgctcg acgttgtacg cgagctgccc gacatgcctg acctgcacaa caccaacaac
      541 ggcaccgtca cgaacctcat ccaagctcgg gacgtccacg gcaacatctc cttcgggccg
      601 cagtaacggg cgtactggag gcggtgcggc ggtggacttc gagccggacg cccggatcaa
      661 agagcttgac ctgtcggagc ccgtcgacat cggccgcgtg gacgtactga ccggacggca
      721 ccgtcgatgc gtcgcggtct ggctccagcc gagcctggaa tggagatcgt ctgtcgggac
      781 cggcccgcac ctatgcgaca ctgctgcggc gtcatgcgag ttggagcacg cggaggcggc
      841 gtgcgatgcg gcctggtcga cggcgacggc ggaccagcgg tgggtggccg ggctggagca
      901 gtaagagccg gtgctccatg cgctggagtg ggcttgatcc gctttggcgg acatccgaga
      961 tcaggggttg agtccccgga aggatgtcca ccatggagag catggggaag aagaagccgc
     1021 gtcctcgccg ctcgttcacg ccggagtgca aggccgagat cgtcgagctg tgccgacgtg
     1081 gtgaccgctc ggtcggccag gtcgccaagg acttcgacct gaccgagacc gcggtgcgcg
     1141 actgggtcaa gcaggccgaa gtcgatgcag gcgagcggga cggcctcacc cgcagcgaat
     1201 gcgaggaatt ggcccaactg cggcgggaga actgccgcct gcgcgaggac gtcgagatcc
     1261 tcaagcgggc cacggctttc ttcgcgaagg agacccggtg acggtgcacc cgttcatcga
     1321 ggcggagaag caggcgggcc acagcgtcaa acgcgcgtgt gaactgctga aggtctcccg
     1381 tgccgccttc tatgcccgcc gcaccggcgc cgtcggcccc cgggccgtgc aggatgcgga
     1441 gctcaccgag cggatgaccg ccgtccacga ccggtcccga ggcacctacg gggccccgcg
     1501 catccacgcc gccctcaagc gcgagggcac ggcctgcggc cgaagacgca tcgcccggct
     1561 gatgcgggcc gccgggctcg ccggccgcca ccgcagacgc cgacaccgca ccacgatcgc
     1621 cgacccccac gcggccaccc gcccggacct ggtcctgcgc gacttccggc ccgacccgac
     1681 cacggctgac gtccgctggt gcggcgacat cacctacatc cccaccgacg agggctggct
     1741 ctacctggcc accgtcatcg acatcgcctc caggcgagtg gtcggctggg ccaccgccga
     1801 ccacctgcgc accgagctgg tcgccgaggc gctgcggtcc gcctgccacc gacgccgccc
     1861 cgccgggtcg gtgatcttcc attccgaccg cggctgccag tacaccagcc atgaattcgc
     1921 cctccttgct gccgagttgg atatccggct gtcggtcggc cgcaccggcc agtgctggga
     1981 caacgcgctg gccgagtcgt tcttcgccac cctgaagaac gaactgtacg gcgaccgccc
     2041 ctggccgagc aggtccgtcg cccgcacagc ggtcttcgag tggatcgagg gctggtacaa
     2101 cttgcaccgg ctgcacagca gcctcggcta ccgcagtccc gctgactatg aggccgccct
     2161 ggcggcctga ccaccacacc gacggtgtcc gtcaaagcgg aacaagctca cccgggcgtc
     2221 ctcgtcggta acgcaacgac ggatgagctg gtactcgtcg tgctccagga agaccatctc
     2281 ctcgacgatc tcgtcgtcgg ctcgaggcag ccgggtgccg gcgcagcagt tcttggtcct
     2341 gagcgggggc tcggcctcga tcgcggcctg gacgatgcac cacaggagac cgtgccggtt
     2401 ggctatggac ttgggagcgg caggtcggcg gatccaccgc cccgtcaccg gatcctgctg
     2461 gccggcctcc tggaggcgga tccagtcgtg cacgtcgtca gacgtgatgt tgccgatggt
     2521 ggctggcatg agctgtcccg cccgcgtcgt atgcacgaag agcgagagat ggcggtccac
     2581 ttcgcggaga tagtcgtcac gggtccggct gtcgatgccg gtgagacgct ccaagtagcg
     2641 gcgtgaccac tcggcgagcg gtacgtcgtc ggggtcctgc tcgggttcga caaagccctg
     2701 gctcgggacc cagccgaagg gccactgctg gccgtgagcg tcaacgagct tcttgaacgc
     2761 ctctgcctcg gccagctctc cgaacctctc ggactcccac gaaccgccac gccctccctg
     2821 gagccagcgg acctggaaac tcgccgtgcc gtccttgcga atccgattcc tgatggtcgc
     2881 catgggaccg gacagtagat cgaaaatccg gccgcgtttg gccgccgttt ggccaagccg
     2941 ggagaccaaa aggcccctgg cctgcgtttc cgcaggccag gggcctttca gacaagggtg
     3001 agtgacggga ctcgaacccg cgacatcctg gaccacaacc aggtgctcta ccagctgagc
     3061 tacacccacc atgaccggcg gtggaagtcg tttccccgac cggccgagaa gaagtctaca
     3121 gggtccgcgg gggtgctcgc gcacacgttt tacggcaccc ttgcgcggga cctccgaaga
     3181 cttgcgggaa gacttactga gcaggcagga cgtgcttggc ggcgatcgcc ttcgccgtgt
     3241 cggagtcggg accgggctgc gggacgaaga tggcctcgcg gtagtagcgc agctcggcga
     3301 tcgactcgcg gatgtcggcg agggcccggt ggttgccgtt cttctccggg ctgttgaagt
     3361 acgcccgcgg gtaccagcgc cgcgccagct ccttgatgct ggagacgtcc acgatccggt
     3421 agtggaggtg gctctccagg gccggcatgt cccgctccag gaagccgcga tcggtgccga
     3481 cggagttgcc gcacagcgga gccttgccgg gctccttcac gtactgcttc acatacgcga
     3541 ggacctgctc ctcggcgtcc ttcagggtcg tgccgttcgg gagctcggcg agcagcccgg
     3601 acgcggtgtg catctgacgc accacctccg gcatcgtctc cagcgcctgg tccggcgggc
     3661 ggatgacgat gtccaccccc tcgccgagta cgttcagctc ggagtcggtg acgagggcgg
     3721 ccacctcgat gagagcgtcg tcggacagcg agaggccggt catctcgcag tcgatccaca
     3781 ccatgcgatc gttcatgcga ccaccctaaa gctggcctga gcttttcggt ccccctgcgc
     3841 cggcgctggg ccggcctgta ccgaaaagaa acctgtactg aaaagaaagg ggggcgagtg
     3901 tggactcgcc cccccttctc ccagctaccg ctccgtctct cagctaccgc tccgcggccc
     3961 cggcagcagt cccaccgcgc ccgccgcctg gcggcgggtc tgcatcggga ctccgttgtc
     4021 gcggtccggg tgcagcatgg tgggcgagtg acctatcgca cctgggccag gcaggcccgg
     4081 gggcgggccc ggcgcgggca gcgccggctc cgcgtcggcc ggccggtcac cctgcggccg
     4141 gcgggcccgg taggcggccc ggtaggcggc gggggacgag ccgagctggc ggcggaagtg
     4201 gccgcgcagc gcgacggggg agcggaagcc gcaccggccc gccacctcgt ccacggagta
     4261 gtccgacgtc tccagcagcc gctgcgcctg cagcacccgc tgcgtgatca gccactgcag
     4321 cggcgcgctg ccggtcagcg agcggaaccg gcggtcgaac gtacggcggc tcatataggc
     4381 gcgtgccgcc agggtctcca cgtcgaactg ctcgtggagg tgttccagcg cccaggcgac
     4441 gacctcggcg agcgggtcgg cgccgatctc ctctggtaaa gatcgatcga ggtagcgctc
     4501 ctggccgcct gtccggcgcg gtgggaccac caggcgccgg gcgagcgcgc cggccgcctc
     4561 gttgccgtgg tccgtccgca cgatgtggag acagagatcg ataccggccg ccgtacccgc
     4621 tgatgtgagc acgtcgccgt cgtcgacgaa cagctcccgc ggatccacgt ggaccgacgg
     4681 gtagcgcttg gccagcgtcg gcgcgtacat ccagtgggtc gtcgccgggc ggccgtccag
     4741 caggcccgcc gccgcgagca cgaaggcccc ggtgcacagc ccgacgatgc gggcaccctc
     4801 ctcatgcgcc cggcgcagcg cgtcgagcgc ctcttccggt ggtggcgcgg tgatcgaacg
     4861 ccaggccggt acgacgaccg tcccggcgcg tgagatcgcc tccagcccat gtggtgcggt
     4921 gagttccagg ccccctgtgg tccgcagtgg gccttcctca ccggcgcaca ccagtagtcg
     4981 atagcgcggc accccggcgt cctggcggtc gatgccgaac accgacagcg gaatggaact
     5041 ctcgaagata gggccgccgc tgaacagcaa caccgcgacg atctccttgc ggcggcgccc
     5101 ggagagtttc cgggcagcgg cctccggtgc ggcagtggag tcgtggctca tactgctaag
     5161 cccccctcgg tggtcgcggc tcctcggttg tgtcgctcct gcacgtttcc cctcggtcct
     5221 gcacgagtcc cccgccgtaa gacagtcaag atcgaatcta ctggctcccg cggtctcacg
     5281 gtgaccagtt ccacacgccc cagattgtcg acatgacaac ttggcgtgaa gcattcgatc
     5341 acgaagcgtt gcactcacaa ggcgtgcagg gaagtgcgcc tcgtcgcagt ggccaaaccg
     5401 cgtagggtgc acagctgccc gtagaccctt tccgtgcagg tcgaacgggg gttggagggt
     5461 ggttcggggc cccctggagc gacattcaga agttggctga aaagaagcgt tcgggggtac
     5521 ggaaaccggt cagtcgaccg gtgtccgtcg gcgggtgtga cgtccacctc tttgcaccgc
     5581 gcaacgcttt gcgcgacagg cgtgccgctc ggcacaccgc tcggaccggc gcagcaggat
     5641 ccggcacgcg gccgtgaccg cggccaggcc cagtgcggcg cccgccgcgc cggccagcga
     5701 ggagccgtac cagacgagga ccacggggac gagaacgcag ctgaaggcgg cccagcggat
     5761 cacatcgctc acggtgtccg gcgcggaagg cggctcggag gtggatcggg gaccgggcat
     5821 cactcgtact ccctgtggcg gtgggtcacc cgggttcaac gtctgttcga ccggtcggtc
     5881 accggccgca cgtatgtgaa tcctgagcaa accgcctgta cggggcagca accattgcgt
     5941 tacgggcgtc gctcgtgcat gctccggtga acccctacgg acgtcggggg accgcttacg
     6001 gagcgtgcgc gggaactgtg ctcaggaggc gtgccgccgt acccttgggg gtatggggtt
     6061 gggaagatgt ttcccggaca cagctccgtg acacagctcc gcgcacactg tcgtccaccc
     6121 ataaaggatc acaacgccga gacagtcatg gccggtcacg aattcttcga acccgcggac
     6181 cgcaagcggc cggtcgccga tcccacggcg gccgatcccc tggcggcgga agagtcacgc
     6241 ccctcatgcg accctgcctt ccggcacgga gtcgtcgtcg gcttcgacgg ctccacctcc
     6301 agtgagcgcg ccctcgccta cgccatcggt atggcccacc gctcccgctc gggcctgatc
     6361 atcgtccatg tcgccaaccg gctgccgacc accgtgtggg ccggctgtga gccgcccgtc
     6421 ttcgtcgacg tgccggacca tcgcaccgag gtcctcgggc tggagctggc gtgcgcggac
     6481 tatctggccg aggtgccgtg gatcctggtc gagcggggcg gggacatctg ccacgaactc
     6541 gaagaggtgg gccgggagta cgaggccgac gcgatcgtcg tcggctccac acacggcatc
     6601 gtcggccgga tcttcggctc cgtcgcgggg cggctcgcca agcgggcgca gcggcccgtg
     6661 atcgtcatcc cctgagtact ccgacgaata ctccaactcc ctttgtgcag cgcgaaacta
     6721 ctcgcgcgta gaggtggttt gtgcccttgt gaagggcata tatcggtcac cgcgcaacag
     6781 cacagcatga agggagcccg ccgtggacaa cggaagtact acggtggtcg gccgactcgc
     6841 cctgggaatc accctgttgg cgttcggcct cggcacgaca ggcgtgatcc acggtgtggc
     6901 cgcctccgac gccgtgtcag tggcccacta tgtgggtgga gttgctctgt tcctggtcgg
     6961 cctgctggcc ttccgtggcg gcgacggcgt ttccggtacg ggcttcgcgg ccctcggcgc
     7021 gctgtggttc acctgggcgg tcggcggtca ttcctccgcc aacgcagccg gactcttcct
     7081 gctcctcttc gccctcgtgg cgctcaccct gacgctcgcc ggcggggaca gcctgggtca
     7141 ggtcatgcac gggctgctgt tcctggcgat gctggtgctg gccgtcgcgg ccttcgccga
     7201 cagttcgtcc ctgtccaagg tcgggggctg ggtcgcggcg gtgtccggag cggtggcctg
     7261 gtacgcggcg actgcgtcgc tggctcactg gcccactgct cttcccgggc gtgccgcccg
     7321 ccggggggtg acggccaccg gctgatacgc agcggcacgg aacggccccc cgcgtgcatg
     7381 gtggcacacg tggggggccg ttctgttgtc ttgcctgtgc agcgccgtcg tggtttcttg
     7441 cgcccacgcg gcggcagccg cacattgata cagccccgcg cccctggggg actactccac
     7501 cgtcaccgac ttggcgaggt tcctgggctt gtcgatgtcc ctgcccaggg cctttgccgt
     7561 gtggtacgcc aggagctgga gcgggatgcc catcaggatg gggtccagtt cgtcctcgtt
     7621 cttcgggacg acgatcgtct ggtccgcctt gtcctggtgc tggtgggcca ccgcgaggat
     7681 cttgccgctg cgggccttga tctcctccag ggccgcgcgg ttcttctcca ggaggtcgtc
     7741 gtcggggacg atcgccaccg tgggcagggc cggctcgatc agggccagcg ggccgtgctt
     7801 cagctcggag gcggggtagg cctcggcgtg gatgtaggag acctccttga gcttcaggga
     7861 ggcctcgcgg gccaccggat agccccggac gcggccgatg aagagcatcg agcgggcgtc
     7921 ggcgtacagc tcggccagct ccttgatctt ctcctcctgc ttgaggatct cggtgatctg
     7981 ctccggcagc ttgcgcagac cctcgatgat ccgcttgccg tcgcggaccg agaggtcacg
     8041 ggtgcggccg aggtggaggg cgaggagggc gaaggccacg gtcatgttcg tgaagcactt
     8101 cgtcgagacc acgcagacct cgggacccgc gtggacgtag atcccggcgt ccgcctcgcg
     8161 cgcgatcgcc gagccgacga cgttgacgac gccgaagacc ttggcgccct tgcgcttgag
     8221 ctcctgcacg gcggcgagga cgtcgtacgt ctcaccggac tgggagacgg cgacgtagag
     8281 ggtgtcgggg tccacgaccg cgttgcggta gcggaactcg gaggccggct cggcgtctgc
     8341 cgggatccgg gccagctcct cgatcatctg ggcgccgatc atgcccgcgt ggtacgaggt
     8401 gccgcagccg aggatcttca cgcggcggat ctgccgggcc tcacgggcgt ccaggttgag
     8461 gccgccgagg tgcacggtgg agaagcggtc gtcgatacgg ccgcgcagca cgcggtccac
     8521 ggcgtcggcc tgctcgaaga tctccttgtg catataggtg tcgtggccgc ccatgtcgta
     8581 cgactcggcc tcccactcca cggtcgtggg ctcggcggtg gtgcgcgtgc cctcggtggt
     8641 gtaggtgcgg aagtcgtcgg ccttgagggt ggccatctcg ccgtcgtcca gagtcactat
     8701 ctggcgggtg tgcatgacga gggcggcgat gtcggaggcg acgaacatct ccttctcgcc
     8761 gatgccgagg acgaccgggg agccgttgcg ggccaccacg atccggtcgg ggaagtcggc
     8821 gtgcagcacg gcgatgccgt acgtgccctc gatcacccgg accgcctggc ggaccttgtc
     8881 ctccagcttc tcggccgtgg agcgggcgat gaggtgggtg agcacctcgg tgtcggtctc
     8941 ggagaggaac tcgacgccgt ccgcctccag cttgcggcgc aggtcggcgg cgttgtcgat
     9001 gatgccgttg tgcacgacgg cgaccttgct gtcggccgac atgtgcgggt gggcgttgac
     9061 gtcggagggg gcgccgtggg tggcccagcg ggtgtgggcg ataccggtgg tgcccttgaa
     9121 gcgcgccggg accttgacct ccaggtcgcg cacccggccc ttggccttga ccatcttcag
     9181 accgggcgcc ttcggggagg tgacgacgat gcccgcggag tcgtagccgc ggtactccag
     9241 ccgctgcagg ccctccagga ggagaggggc gacgtcacgc ttcccgatgt atccgacaat
     9301 tccgcacata tataggtatt ccgtatttct agccgtagac gatgcggcgc agctgcctga
     9361 gcgtcagctc cggcggtgcc accgcgcggt atttcagatc cgccccgatc cgttcgaaga
     9421 tctccgcgtt caccagaccc tgggtctgga gctcgcggtg gcggcgacgg acgtagtcct
     9481 ccgtcggctc gtcgaagaag gcgagcacgt cctggaccac ccgcagcgcc tcgccccggt
     9541 tcagaggcgt ggaccgcgtc agatgatcaa cgagttcgtc gtgcacccgg tagatcctgg
     9601 ggtaccggcg ccggattcgc aagaatcctg cccgatatcg ggcagtgggt catggatcgg
     9661 cctgttgtcg ggctggtgga tctctgttcg ccggctgtcc atcctgtgtc ctgcgtctcg
     9721 ttggagatgt ggaccatttt caggcgccat ggacattcct cgtatgggag tacccgagaa
     9781 gctggccgag cgcatgagca tggccgagca gcatgagtac ctgcgcgcca gattctcgcg
     9841 gcgcaccatg atcagaggcg gtgccgtcac actgggcgcc gtcgtgggtg gcgcgttcgt
     9901 gccgggtgcc accgcccagg ccgccgtgcc gacgcaggcc accgcccccg ccgccgagac
     9961 ggtcgacggc gccctcgtcg cccccttcgg ccgccacctc gcctacggca acgacccgcg
    10021 cacggagatg accgtctcct ggcaggtccc ggtcgccgtg aaaaacccgt tcatccgcat
    10081 cggggcccac ccctgggacc tctcccgcaa gatagaggcc gaggtccgca gcctctacac
    10141 cccggccggc gtcggcgcga gcggcgacca cacgcagtac tatctgcacg cccagctcac
    10201 ccacctgcgc ccgggcagga cctactacta cggcgtcggc cacgagggct tcgacccggc
    10261 cgagcggcac ctgctgggta ccctcggcac cttcaccacc gcccccgcgc acaaggcgcc
    10321 gttcaccttc accgccttcg gtgacgaggg cgtcggctac cacggcctgg ccaacaacgc
    10381 cctgatcctc ggccagaacc cggccttcca cctgcacgcc ggtgacatcg cctagggcga
    10441 cccgtccggc cagggcaagt ccacggacac cgggttcgac tcgcgcacct gggaccagtt
    10501 cctgtaccag accgagtcgg tcgccaagca ggtcccctgg atggtctcgt acggcaacca
    10561 cgacatggag gcctggtact cgcccaacgg ctacggcggc gaggaggccc gctggaccct
    10621 cccggacaac ggcccggacg cgaagaacct gcccggcgtc tactccttcg tccacggcaa
    10681 caccgcggtc atctcgctgg acccaaacga catttccttc gaaatcccgg cgaacctggg
    10741 catatctggc ggaacccaga ccaagtggtt cgaggctcag ctgaagaagt tccgggcctg
    10801 cgacgacatc gacttcatcg tcgtgttctt ccaccactgc gcgtactgca cgtccacggc
    10861 gcacgcctcg gaggggggcg tgcgccagga gtgggtgccg ctgttcgaga agtaccaggt
    10921 ggacctggtc atcaacggcc acaaccacca gtacgagcgc accgacgtca tcaaggccgg
    10981 tgccgtcacc aagaagctcc cgatcggcgg taccgcctac cccgagaccg agggcgtggt
    11041 ctacgtcacc gccggcgcgg cgggccgcag cctgtacgcg ttcagcgccc ccgactccta
    11101 cgagggccac gagcacgagg tcgactcggt gacgtccttc atcaacacca aggacggcaa
    11161 ggtcaacgag accgtcacct ggtcccgggt gcgctacctc aactactcct tcctgcgcgt
    11221 ggacgtcacc cccgcgccga agggccggca gaccacgctg acggtgtcgg gcatcgccga
    11281 gaccggcgac cgcatcgacc acttcacggt gtcccgcacg gcgaagtagg ttcctgggcc
    11341 ggactgcggg cggtcctcac atccgcttga ggaccgcctg cttggccagc gtgaattctt
    11401 cctccgtcag gaccccgtcc cggtgcagtt cgcccagctc gcgcaggcgg cgcagcaggg
    11461 cgtcgtggtc gtccccggcc ggcgccttgt cgagcaccgg cggctccttc ggcgcgtgcg
    11521 cctccgctgc ggccggatgc ggcagccgcg cctgtacggc cgcggccacc agcgccatca
    11581 gcgggtccct cttgaagccc cacagctcga cggcgttcgg gtcgtacttg ggcggcgccg
    11641 tgaccggggc gccgctcacc aggaaccgca gatggccgtt ctccagtccc gccgcgggct
    11701 gccacgccac gccgacgacg tccgcgaggg ggatcgtacg ggggccgccg gcggacttgg
    11761 cgtcctcggt cttccagttc cactccagcc tcacccgctc cccgtcgaag cccgccgtgc
    11821 cgtccccggc ggaggcggac accggcagtg cgggccccgg cagcagatac tcggtgaccg
    11881 gctccgggga aaccccgtcc agcagcagcg cgttgcgcac ctcgtccgcg aagtactcgg
    11941 cgacgccgta ccggtcggac tccaccgtca gctgataggg atcgttcggc tcggcgagcc
    12001 ggccgccggt ggcctgcgtc agcggatcgg cgccgtcgcg cagccgcagc ctcagccgcc
    12061 ccgacttccg cccctgctcg aaggagacac cggccaacgc ccccagcggt acgacgagtt
    12121 cgcccagctc ccggcggagc aggctcacgt tcttgtcccg tcccggggtg agccgcaggg
    12181 cgtcgccgtc gaaggcccag gtgccgtcct tctggatgat ttccgccatg gagggattgt
    12241 ttcaccggat ctgcgggaca gtggtctcga ccatgtctga cgaacatgtc tgacgaacga
    12301 ccacgtccga cggtcacacc cccatctgaa gggagcgcat gtgagacgca accacagcac
    12361 gactccccgg acacctggca tcctcggttc cctgctgctc gtcgcggcgg ccggggtctt
    12421 caccctgggc gccgccccgg ccgccagagc cgccgccccg gcccccctcg gccaggtggt
    12481 cccggcgccg gcctcggtcg caccgggcgg cgccccgtac cgcatcaccc gcgggaccgg
    12541 cgtccgcgtc gacgactccg ccgaggtccg ccgcatcggc agctatctca ccggtgtcct
    12601 gcggccctcc accggctatc cgctgccgct caccgaccat ggcagcggcg gcatccgact
    12661 ccacctcgcc cagggcgact tcggcgccga gggctaccgg ctgcacagcg acgcggccgg
    12721 tgtcaccgtc accgcgagcg cccccgccgg cctcttccac ggcgtccaga ccctccgtca
    12781 gctcctcccg gcggccgtcg agaagaggac cgcccagccc ggcccctggc agatcgccgg
    12841 cggcaccatc gaggaccgtc cccgttactc ctaccggggc gccatgctgg acgtctcccg
    12901 gcacttcttc accgtcgccc aggtcaagcg gtacatcgac cagctggccc tgtacaagat
    12961 caacgagctg catctgcacc tcagcgacga ccaggggtgg cgcatcgcca tagactcctg
    13021 gccgcgtctg gccgactacg gcggctcgac cgaggtcggc ggcggcaagg gcggctacta
    13081 caccaaggcc gagtaccggc agatcgtctc ctatgccgcc tcccgctacc tggaggtcgt
    13141 ccccgagatc gacatgcccg gccacagcaa cgcggccctc gcctcctacg cccggctcaa
    13201 ctgcaacggc caggcaccct cgctgtacac cggcacggag gtcggcttca gctcgctgtg
    13261 cgtgccgaag caggcgacgt acgacttcgt gaacgacgtc gtccgtgagc tggccgccat
    13321 caccccgggc cgctacctcc acataggagg tgacgaggcc cactccacca gccacaccga
    13381 ctacgtgacc ttcatggacc gcgtgcagcc catcgtcgcc aagtacggga agacggtcat
    13441 cggctggcac cagctcaccg gcgcgcatcc ggccaagggc gccatcgccc agtactgggg
    13501 cctggacagc accagcgcgg ccgacaaggc ccaggtcgcg aaggccgcgc agaacggcac
    13561 cgggctgatc ctgtccccgg ccgaccggat ctacctcgac atgaagtaca ccaaggacac
    13621 caagctgggc ctggactggg cgggcctggt cgaggtgcag cggtcgtacg actggaatcc
    13681 gggcgcctac ctgcccggcg ccccggccgc cgccatcagg ggcgtggaag cacccctgtg
    13741 gtccgagacc ctgaagacga acgccgacat cgactacatg gcgttcccac gactcccggg
    13801 cgcggccgag ctgggctggt ccccggcggc cacgcacgac tgggacgcgt acaaggtgcg
    13861 gctggccgcg caggccccgc gctgggcggc cctcgggatc gactattaca ggtcgccgca
    13921 ggtgccgtgg cccgcttcct agggtgaaag gccgacgggc tccccgcagg accgtactgc
    13981 ggggagcccg tcggtctgga tcagaacccc gcgatgggat ttttcagggt tccgaccagc
    14041 tggagggcgc ccgacggatc cgccaggtcc accatctgcc ggttgtcgcg cagctggagc
    14101 cggttgaggc aggacagtgc gaactcgggg gcgaacatgt cgtactgccg gaatttgtgg
    14161 gcgagttccg ggttcgcgtc ctgatactcg cgggtgacct ccgcgaccgt gcgccagaag
    14221 gcgtcttcgg ccaggatccc ctcggtggcc aggtgtgcgg cgaggaagcg gaagaagcag
    14281 tcgaagacgt ccgtgaagat cgacaggagt ttcctgtcct ccgggacgtc ggcacggatc
    14341 cgcgcgacct ccgggggcag gaccgcgtcc gggtccatca ccacgatctc ctcggcgatg
    14401 tccttgtaga tcgcgcgctg gacggccccg tccttcaggg ccaggatcac gttctcgccg
    14461 tgtggcatga aggcgaggtc gtaggcgtag aagctgtgca ggaggggcgt gtagtacgcc
    14521 cggaggtact gccgcagcca ctccgtcggg gtgagaccgg accgctcgat cagcgcgccc
    14581 gcgaaggagg cgccctcgtg gtccacgtgg aggagggagg ccatggtggc gagggactcg
    14641 ccctcccgca ggcccgacac cgggctctcc cgccacagcg cggccagcat cttgcggtac
    14701 ggcgagtagc ggtcggtggc ctgctcgtac tccaggtgcc ggtagccgac ggccgcccgc
    14761 tcccggatga tcgtgaggcc ggtcgacttc agcaccgggt cgttctcgat cagctgggcc
    14821 agccagtcgt tgatcgccgg ggtcgcctcc atgtaggcgg ccgaaagacc gcgcatgaag
    14881 cccatgttga ggaccgagag ggctgttttc acatagtgct tgtgcgggtc gctggtgttg
    14941 aagaaggtgc gtatcgattg ctgggccagg tactcgtcgt cgccctcgcc caggcagacc
    15001 agatgccggc gggccacctc ggcggcgaag gtgacggaga gcttgttcca ccactgccag
    15061 gggtggaccg ggatgaggag atagtcggcg ggggcgaggc cctggtcggt gagggtcgcg
    15121 tggaaacggg tcagcgtcgg ctcgcccagc tcctcccgca ggaaggactc gtactcgatg
    15181 ccgaccccgg ccgtgaacgc cgcccgcgag cggtgcgcgg ccagccacac cagccggacg
    15241 gggctggcgg tctccggggc gtacgcgagg tactcgtgga tgccgaagcc gagccgtcca
    15301 ttgttcgcca cgaagcaggg gtggccctcg gtcatcccgg tctcgatcgc ctggaagccg
    15361 ccgcccgcca gctccgcgga ggtgacgcgg ggcttggtga gcttgtagca ggtgccggag
    15421 agggtggagg agatctcctc cagatagacc ggcaggatct cgtcgctcag gcccagagag
    15481 tccttcagct cgatgaagaa atccagggag gagaggggga gttcggcgcc ttcgcggtgc
    15541 cgggtgaggg tgtcggcgtc gatctgccag tgatccaggg cgcggcggac ggcggagaag
    15601 cggtacgcgg tgagaccgtc gtcgccgcgc acgacgtact gctcaccctc ctgctccggc
    15661 gtgatcaggc gctcgtgcgc gaactcggcc agcgccttgc ggatgagcag acggttggcg
    15721 gtcgcccagc gctcggggga cagatgggcc acggcgtcgg cgaggctcat gcggccaccc
    15781 ccgtcgcggc ggcgaactgc tcgcgcgtgc agaagctcag cagcgccttc ttctccggct
    15841 tccggatctc ccgctcgggc acgaacccga cggcctcgtt caaggcgtgc acggctttgt
    15901 tgcgcacgtc cggctccacg acgacccgca gggtcgccgg atcctcgaag agacgggcca
    15961 tcacggcggt gatgacggac cgggtgaagc cgtgcacggg cgtgtcggtg gccggagtga
    16021 ggaagtgcat gccgatgtca ccgggctgcg cctcgtacag gccgaccagc tcccggtgcg
    16081 ccgggtcgta cttctccatg aggaaggcgg gctcgccgcc ccgcagcccg agcagcgcgt
    16141 ggtggtgtgc gtccgccgcg atctccatgt acgcccgctc gacgttctcc agcttcgcgt
    16201 cctgcatcat ccagaaggac gccttgggat gggtgaccca ggagtgcagc agttcggcgt
    16261 cctgcaacgg gtcgacgtca cggaaggtga aggtcatgcg gagaactcct ggaacgcgat
    16321 ggtcttctcg accgggtagt actcggtgcc gagcagctcg cggatgatgt acgagttgcg
    16381 gtacgcgccc atgcccaggt cggggctggt gatgctgtgg gtgtggacgc cggcgttctg
    16441 caggaagacg ccgcggccgg tgacgtcgac ggcgtagttg cgggcgacgt cgaagcggcc
    16501 gtggccgtcg aagagcagac ggtcgcggat cggggcgagg aacgccgggg gctcgtagtg
    16561 gtagccggtg gccagcagca ggccctcggt gccgatctcg aagtccttgt cctgctcgtc
    16621 ctggtggaag ccgagggtgt agccgccgtc ggcgtcgtaa cgggcgctgg tcaggctgga
    16681 gttggtgagc aggcgagtgg ggacggggcg gtcgccgctc gtgacgttct tctggtagag
    16741 caggtcgaag atcgagtcga tcagatccga gttgatgccc ttgaacaggc ccttctgctg
    16801 cttctccagc cggtagcggg tctcctcggg cagcgctcgg aagtagtcga tgtagtccgg
    16861 ggacgtcatc tccagggtca gcttggtgta ttcgagaggg aagaagcgcg gggagcgggt
    16921 gacccagttg agctggtagc cgtaggagtc gatctcggcg agcagctcgt agtagatctc
    16981 ggcggcgctc tggccgctgc cgacgatcgt gatggacttc ttcgactgca gctccgcctt
    17041 gcggtgcatg tactgggagt tgtgcacgaa gtcaccgccg aggtcccggc aggcctgcgg
    17101 gacgaagggg accgtgcccg tgcccaggac cagatgccgg ccgcggaacg tctccccgcg
    17161 ctcggtgcgg acgacgtacc gctcgtcctc gtacgtcacc tcggtgacgg tcgtgccgaa
    17221 gcggacgctg cccagtttgc ccgccgccca gcggcagtag tcgtcgtact cgacccgcag
    17281 cggatagaag ttctcgcgga tgtagaacga gtacagtctg cccttctcct tcaggtagtt
    17341 gaggaaggag tacggcgagg tggggtcggc gagggtgacc aggtccgaca tgaacggggt
    17401 ctgcagatgg gcgccgtcga ggaacatccc ggcgtgccac tcgaagtccg gcttggagtc
    17461 gaggaagacg ccgtcgaggc cgtcgatggg ctcggtcaga caggcgaggc cgaggttgaa
    17521 ggggccgagc ccgatcccca cgaagtcatg ggtgcggctg gcttcaggaa gcgcggtcaa
    17581 gggactctcc caggtactgc tcggcgtggc cggcgatcag atcgaggacg gcggcgatgt
    17641 cggccgccgt ggtctcgggg ttgagcaggg tgaacttcag gtagtggcgg ccaccgacct
    17701 tggtgcccgc gaccacggcg tcgccggagg cgaacagggc cttgcgggcg tagaggttgg
    17761 cgcggtcgat ctcggccggg tcggtgacgg ccgccgggat gtagcggaac accagggtgg
    17821 acagggtggg ctcgacgacg acgtcgaagc gggggtcggc ggcgagcagt tcccagccct
    17881 cggccgccag gtcgcagacc tcgtcgaaga gtgcgccgat gccgtcggcg cccatcaccc
    17941 gcagtgtcat ccagagcttg agggcgtcga atcggcgggt ggtctgcagg gacttgtcga
    18001 cctggttggg gatacgttcc tgcaccatac ggcgcgggtt gaggtactcc gcgtggtagg
    18061 tggcgtggcg cagggtggcc gtgtcgcgga ccaggagagc tgacgaactc accggctgga
    18121 agaaggactt gtggtagtcg accgtgaccg agtcggcgcg ttcgatgccg gcgagccgtg
    18181 cccggtactt cagggaggcc agcagcccgc agccgtaggc cgcgtcgacg tgcatccaga
    18241 cgccgtactg cgcgcacagc tcggcgatct ccgggagcgg gtcgatggag ccgaagtcgg
    18301 tggtgccggc ggtggcgacg acggccatcg ggaccagccc gtcgcgccgg cagcgctcca
    18361 gctcgcgggc gagggcgacg gtctgcaggc gcttgtcgtg gtcgacgggg agggggacga
    18421 ccgcctcctg gccgagaccg agcagtttgg cggacttctt cacgctgaag tggctgacct
    18481 cggaggcgaa gatgcgcagt ccggcgagcg agtcggtctt ggcctcctcc ctcgcgagga
    18541 gcagcgcctg gaggttggac tgggtgccgc cggaggtgaa cacgccgtcg gcggcgggcc
    18601 cgaggccgat ccgggtggcc gtccagtcga tgagcttgcg ctcgatgaga gtgccgccgg
    18661 ccgactggtc ccaggtgtcg agggaggagt tgaccgcgga gagcacggcc tcgccgagca
    18721 ccgccgggat cacgaccggg cagttgaggt gggcgagata gcgggggtgg tggaagtaga
    18781 ccgcgtcctt gagatagacg tcctccagct cgtccaggac ggcggcggtg tcgccgagcg
    18841 gccggtccag gtcgatggcg tcgacgcgcg gggtgagggc gtcgacggtg acgccggtga
    18901 acggacggtc ggtggtggcg agtttcgccg ccacccgctc gactccttcg gtcacggagc
    18961 tgcggtagtg ctccgcggtg aggccattga gcaggtgcga gcgcatgtgg gggtcctccg
    19021 aggggacagt ccgtgcgggg ggtttgatcg ggttcggggt gcgaacgggg tccgtgttca
    19081 acttaggtta gcctaaccta agttttctgg atcaaggcgt gcctcagccg tgaccggcgt
    19141 cacgggcgtg cgggggttac tcggtggccc gcagctgttc ctcggtcatc ccctgccgcc
    19201 agtacccgac gaaggtcacc cgccgccggt cgaccccgcg ctcaccggcg aagtaccgcc
    19261 gcagcgcctt cacttgcccc gactcgcccg cgatccacac atacggccgc tcggagagcg
    19321 ggagtcgggc ggcccgtacg gcgtcgacgg ccatgggggc gccgtcgtgc cgcacgagcc
    19381 aggtgatctc cgcgtccgcg tccgtgcgca cgtcctggat gtccccggcg tgcggcacct
    19441 ccagccaggc gcgggcgcgg atgccggcgg gcagggattc gaggatggcg gtcgcggccg
    19501 gtacggcggt ctcgtcgccc cacaggacga cgaggtcggt gtcctcgggc gggcggaagc
    19561 ggatggcgcg gttgtcggcg atggcgggcc cgagcagcag cacccggtcg ccggcggcgg
    19621 cgcgggaggc ccagcgggag gcggggcctg cgggggtgtg cagagcgaag tcgatgtcga
    19681 tctcggtcgt gtggcccagg gcgtcccggc gcagggcgcg cagtgtgtac gagcgcatca
    19741 ccgcccgtac gtcgtccggc agttcccgcc agccctgcca ccacccgtcg cccagctcca
    19801 ggggtacgac gggctcgggc tggcccggat gcggcaggaa cagcgacagg gactggtcgc
    19861 gtccgtcgga gtggaaggcc tccagttcgg ccccgccgaa ggtgacccgg accagagacg
    19921 gccccagccg cctcgtccgt atgacctgca gagcgaagaa tcggaacggg gcggctacgg
    19981 ccgtcgtcat gtgtggctcc tgaagggggg tgggattcag gactttttgc gtgcgggagg
    20041 gtcagctgac cttcttggcc ttctccaggg cctcggccag actcgtcagc agcggcacgc
    20101 acttgtcgta cgacaggatc ggctcggggg agcgggagat gacctgaccg gccttcaccg
    20161 cgggcagctt cttccaggtc ggcttggaga tgccggcggg ctggatcgcc gaggaacggt
    20221 cgtccatcat gatgatgtcg gcctggtact tgtcgacgtt ctcccagctc agcgactcga
    20281 accagccgcc gccctgcttc ttcgcgctct ccggcggctc cacgaagttc acgccgaggg
    20341 ccttgaagta ctccaggtcg acggagagat gggtgccgga gacgtagaag agctggtcgc
    20401 tcgcgctgcc ggccatcacc ttgaggtccg gcttggcctt ggcggcggcg cgcagccggg
    20461 ccgccgcggc ctcgaagcgc ttcttcgcgt ccgtcacctt ggcggccttc atatcggcgc
    20521 cgagcgactc cgcgaggtcc cacacccgct gcagcggctc ggtgagctga cggtcgtagg
    20581 cggagatgcc gacgctgggc gcgagctgcg cgatcttctt cttcgactcc tcggggacgt
    20641 accagagcgt cccggcgttg tcgaacatcg tggtgatcag cacgtccggc gcgagggccg
    20701 cgtacttctc gatgttgaac tggccccagg tgttgccgag gatcgtcacc ttgctgatgt
    20761 ccatgtcacc ggcctggaca tcgggcttgc ccgcgctggt cttcgtcggc ccgaagacgc
    20821 ccttgacctg gacgccgtag tcgaagaggg ccgcgccgac gccggtgaag gccacgatgt
    20881 ccgccggaac cttgtcgagc ttcacggtcg tgccgcggtc gtccttgaag gaccaggggc
    20941 cggacttggc ggccttcgtc ccgctgcccg cgtcactgtc tttgcccttg tcgtccccgc
    21001 aggccgcgag cgcggcaccg agtccgacgg caccgcccgc gacgagaagg ccgcggcgag
    21061 tgaggtgggt ggcacgggct tgggacatgg gtatgactgc tttcgaacgg ggcggagcgc
    21121 ccgccggaca ggttcgaagg taggttagcc taacctcact cgatgtccag ggccgggggc
    21181 ggccccgggg tgtcctgcgc cataggagcg gaatcggcca ttcgccgcgc gcccgcctcc
    21241 caaccccctc tccttgcctg gttgttgcga tcacgcgcgg ttatgttgat ccgggcgctg
    21301 gcagttgttc gatgacgacc gagtgcggag aaggagcgac cgcgacagtg ggtggagacg
    21361 tgagcgcggt ggaggacgtc gtccgtgcgg acgccgcgtt gctggaggag gacctggccc
    21421 ggttcctcgg atcgctgacc ggccggccac ccggcgctcc gggacacggc tcggcctacg
    21481 ccgcggcgct cgaccgcgca ctgcatctgc cggtcgccga cgccctcggt tccaaggcgg
    21541 ggcaggaggc gctgcgaccg caccccgggg cgcccggggg cggggccccg ctgcggccct
    21601 cgatggtgta ctgggcgtac cgcaactacc ggggcttcgg cgacatttcc gacgcgtctg
    21661 ccgagtcggg tgcgtatgcc gtgccgggcg cgtctgtcgt gcggggtgcg tctgccgtgc
    21721 cggacgcgtc tgtcatgcgc ggcgcttccg tcgtgccgga cgcgtctgcc gtgccggacg
    21781 catccaccgt gtcggacgta tccgccgagc ccgacgccct cgccccgccg cacgcatccg
    21841 acgtgcccga cgcgcccctg gcctccgcgg gggacggcgc tgccctcgcc accctcgctg
    21901 ctgttcggcg ggccgccgtc gccgtgcggg tcctgctgaa ggccgcggtc gcgctcgacg
    21961 acatccagga cggcagcacc gtccgctatg gcgaacccgc gctgcacctc acccacggcg
    22021 tcccgctcgc cctcaatacc ggctcctggc tgatcacggc cgcactggcg cacgcggccg
    22081 acccggccgt cgtggagagc ctgctcgcgg cggtggcgaa cggattcacc gggcaggccg
    22141 tcgacctcgc gacccgctcg gaccgcaccc gcgccgaact gaccgaggcc ccctgcgcgg
    22201 aacggatcgg cttctgggag tcgatggccg cgctcaagac gggcacgctg ttccggatgc
    22261 cgctcgacgc ggcgctggcc gccctccgcg ccgacgcggc ggagcgcgcc gccctggacg
    22321 aggcgatgcg tcaactcggg ctcgccagcc agctcttcaa cgacgtcgcc gacttcgtgc
    22381 cggaactcgg cggcaccaac acccacgagg acctcgacgc gctgagcaac cgcgtcctgc
    22441 tggaactcct cgactccgcg ccgcccgaca tccgtcgcga cccgtccggc gaacggatcc
    22501 gcggctacgc cctcggccac ccgggcctcg accggacgct gctcgccctc gcggccgagg
    22561 cggtggaacg caagcgcgcc gcgaaggagg ccgtgcatcg cgtgtgccgc tcggcggaga
    22621 gcgcggccta cttcgacatc accatcgaac gcaagggtca cctcgtcgac cggctccatg
    22681 acaccctccg gcagcggagc ggcgtatgac ggcgacggcc gccgactgcc tccgcaccgg
    22741 cacccgggcc tggcacgacg ccctggagac caccggtttc gccaccgcgc tgctcgccgg
    22801 aaccctcccg ctcgaccgct atatggccca actgaccgcc taccgggtgg tgttgcgcac
    22861 cctggagacg gaactctccc gcaccgccga accggccgtc gccgggctct ggacggcgga
    22921 ggatctgcgg aaagtcccgc tgatcgagcg cgacctgcgc catttcgcgg tccgcggcgc
    22981 ctccccggtc cgctggccgg ccgcggcggc ggtggccttc gcgggcgaga tccgtacgac
    23041 cgcggtcgcg gagccgctct cgctgctcgg cttcctgtac gtcctggagg gctccaccct
    23101 cggcgcacgg tacttgtccc ggtacgtcac cgacgcctac ggcctgcacg gcaccgacgg
    23161 caccgcctac tacaccagcg gcgaccgggc ccgctggacc cggttcacca cccgcctgga
    23221 cgaggccctc accgacccgg ccacccagac ccgcgccctg gccaccgccg accgcgccta
    23281 ccaccacacg acccgcatca ccgaggccct ctcgtccggc ctgcccccgc gtcagcggtg
    23341 tgccccgtga gcccaagcgc taccgctgcg gctgcgcatg tcccccggct gttcactgtg
    23401 cccggttacg gtcgaagagt tcgcggcgtg cgccggtgtc tcgtccgact ccgccttgcc
    23461 tccagggagg agaacaggta ctcgcctcca tgccgggggc agtctgcggt caggatggcg
    23521 acctgtccgt gatcgtcgcg ggcgacgatc gcgaaggcgt caggcttcgc atcactggtg
    23581 tggggagtgg gccatgctcc gcgagcgtag ctgcgggttt ccgtgcgcat ggtggcgaac
    23641 ggcggacggg cgggcagctc agccaacgac cggcacgaga tgttcagcgg agtcgagcca
    23701 cactcgctgt ccctcacggt tcacggtcaa tccgaaccgg tcccggctgg gccgttcctg
    23761 ctcctcccac catcgccagg ccgcctccac tccgtcccag agccgccggg gccctgactg
    23821 ccgcacgctc gcaccttcta cgcgggccca ggaaccgtca gcggcccaca ggcggcagcc
    23881 gatcacccgt cggtcgttgt ccaggtcgga cgcctgggcg gtgccgggta cgaccaggga
    23941 gagcaggaac gggaacgcgt cgtcccggaa gggcatggac gcctcaaggt gggttgtgcg
    24001 ttcgtctggg tcctgtgggt cacctggata gggggctgcg cccgtttcac cgattgaccg
    24061 cacgctcatg aagtacgagg gcgtgaccag gaagcggccc gaagcagttc cgtcgccgcc
    24121 gacggtcaac cgggctgttc cccatccgag cggggacacg atcacgccgc cgggcctgac
    24181 ctgctccacc cacgcatacg gcaggcgggc aaaaccacag gtagcgatca accggtcgta
    24241 tggggcaccg gcggagtgcc ctgcgcggcc atctccggtg aggacagtag gcgtgtagcc
    24301 gcaggccctc agccgcgcct cggcgagctt ggtcaactct gggtccacct cgatcgaagt
    24361 gacgttggcg gacccgagtc gagcggccag aagcgccgcg ttgtagcccg tgccggtggc
    24421 gacctccagg acgctcgcgc cctcggtgac gtccagggcg tgaagcatga cgagcatcag
    24481 accaggggcg gtagaggatg aggtggcggc accctcagtc atctgcgtca cgagaacgtc
    24541 atccgtgtag acgtggctga gccagccgac atccgcagcg gtgaggcgcc ggtccggtcc
    24601 gagtcagaac tcgggcacga acacgtggcg aggtacctcc tcgaacacct tcctccatac
    24661 cggatcggtc aggtctccct tctctgcgag tgcggcggcg aggtcgcggc gcaggcgccg
    24721 ggcctcgtcg gtgtcagagg tggtcacggt catgaggtct tgccttccgc gaggagttcg
    24781 gcgagggcgg cggcgatcgg cagcccggtc gaattctgaa tccacgacca ctcacccgac
    24841 ggattgcact cgaacagcac ccagtcccct tgcggggtga ctgcgaagtc gaacgcgccg
    24901 aagttgaggt tgaagcggtc gagccagccg agcacgccgc gacgtacggg ctccgggact
    24961 gtgcacggct tataggtgag cgcgtcgtag tcgctgcgcc agtcgatccg ggccgcgtcg
    25021 ctgccagcgt ggatctcggc ggcgaacagc cggtgcccca cgaccgtcag acgtacctca
    25081 tgggccttgt cgatccactc ctggaacagg tgggcggtca gggacgcgct gtcgtcgatc
    25141 tcggccgggt cgatcagatg ggtggggacg ccgttgcgac ggccgtcgtc gtagcgcaag
    25201 gggctgccca tcagcggttt gcagatcacc gggccgccga tgctcttgca gaacgcgcgc
    25261 gccgcgccgg ggtcggtgct gatcagcgat cgcggcgtac gcaggccgag ggctgcggcg
    25321 atggggagtt gtccgggctt gtgtgaggcg acgccgtcga tctcggggcg gttcacccac
    25381 agcacgggga gggcgtagag ggtgccgagg agaccggcca aggcttgatc gtcggcccat
    25441 gtgcggtgtg gctcggggat ggtgctggag acggcaggaa ggcggggccg ccggtagtag
    25501 acggccctca cctcctccaa ccgcaccgac cggtatatgt cggtgaggac gccggaccag
    25561 ggggccgcgt cgtgttcggc ggtgagcgtc attcgctggg ggaagtcgcc catgtcgaac
    25621 cgcatgacgg gcaccttccg ccgcgtcaac tcgtccacga cgagatctgc ggtggggtcc
    25681 atctcctcgg tgacgaccag tacagcgtcg cttggaagtc gttgcgtcac cgacagatca
    25741 ccggatcacg taggggtcgg acgtgtcgtc gttcttgctg tcccagttgg tgttggtgca
    25801 cgacgcccgc agggtggagt gtgcgagaag ggtgccgtcg ctcatgacgt tgacctggcg
    25861 ctggtggtcg taggcgaacg tggagccgtc cacgtcgatg gtgtagggct gacgctcggc
    25921 acgggcgccg aacgggatgg tcgcggtagt cacatctacc tccatgtgtt tggcggtgca
    25981 gtgaccctgc cggggctcag catggtgtga acgagcccgg ccccggcagg gggactttcg
    26041 ggtggcgctg ctcagctcgt ttcagtgcga cagcgggggc agcggcatgg gggccaggcg
    26101 aacgagtcca ctaggcgttc cgggtcgggg ttggccgtga ccgtaaggtg tctggactgt
    26161 gcgaggcgct tgccgtcggg ggcgagccgg tcgatgtgga tcgtcaggcg ggattccccg
    26221 ggctggggcg gcgttccggc gttcaccgcg cgcctcccgc gacaggggcg tggcaggcac
    26281 aggggcagcg acgcatcagc agcaagccca ggctgccggg cagtggcacg tccgccgtct
    26341 gatggcaggc gtcgtgcagg tcctcgtagc cgggccggag ggcgagcgcg cactcggccg
    26401 acagccacgg cgtgtccgcg cccttccccg tcccctgtgg ccgtttcatg gtcgcgccca
    26461 tcacgccacc gcctcggcgc cgactacgtg ccggtcgagg tcgatgccga agtccgctac
    26521 gaggacgtag gggcggacca gcgccgtcgc ccgaccgtcg aggggcacgt caagcccgta
    26581 cggggaccgg tgagcgggaa ggcccgggga ggccgtgcgg ggcgcctcgg gctggtcgac
    26641 gggtaccggt cggatggggc gcgcagtcag ccggcgccta ccggtactgg gcgcgaacac
    26701 gcccagtacc catcgcagga atgcgtggat aatgcccact gtcatcagct ccactcagtt
    26761 ggtggccacg ccccggggcc gtcgcgagcg gtcgccgggg ttagctctgt cgatgtattg
    26821 agcgttgtcc atcgcgtgca attgcgggat gaccggcggg cgttaccgag gcggtaatac
    26881 actcgttgcc acttcggaag tgctccgcac tgcgcatacg atcactccgg aagttggccc
    26941 catggacgac accacccccg gcccgctcgc ccctggtgtc ctcgacagag gcgacctcaa
    27001 gcgagccctg gcagagcacg acttcgcagc cgcattcgca ctcatcaaga agtggggcgg
    27061 cctctcgcag aaccgcatcg ccgcggcttg ccagctcacg ccaggcaagg tctcgacgat
    27121 catcagcggt cggcagcagg tcaccagctt cgaggtgatc tgccgcattg ccgatgggct
    27181 gcgaattccc gggcggatgg tgggacttgc cgaccggccc tgggaggcgc agcccgacat
    27241 cccagaccaa ccgacaccta ccccggcgac ccgattaccc gttgaggacg agtcatggat
    27301 tcccacggcg accgtgcacc tgaccggaga cctgacgagg agtgaccttc tgatggaccg
    27361 tcgtgcagca acatgcgcca tcgccggcgc ggctctgtcc ggcgccgcgc tcctcgactc
    27421 ccttgagggt tggctccagc ccgcgtcagc ctcggggtcc ggcacatacc accggggccg
    27481 catcggaatg ggtgaagtac ggcagctgga aggaacagcg cgcgcgttcc gagcgtggga
    27541 ccatcggtac ggcggaggcc tccgtcgtaa ggctgtcgtc ggccaactca acgaggtcgc
    27601 aggccacctt gaagagcacc aggcgccaga tgtcgagcgg ggtctgttcc aggtgatggc
    27661 ctacctcgga ggcacggccg cgacgatcgc ctgggactcc ggactccagc ggcaggcgca
    27721 gtcgtactac ctgctcgccc tgcgcgcggc ccacgccgcc ggcgacgccg ccttcggcgc
    27781 gaacgtgctg gccggtatgg cccggcagat gctgtaccgg gaccgtccac cggacgcgct
    27841 cgaactggtg cacctggcgc agaaaggtgc gcgccgagct gcaggaccgc gtctgcgggc
    27901 gatgctgcac acgcgggagg cgtgggcgta cgcggccatg gggcgcgcgg cggccttcca
    27961 acgggccacc ggcgaggcgg ccgaggctct cgccgacgca ggggcggacg atgagccgta
    28021 ctggatctcg tacttcgaca atgcggagct gtccggtgtc accggcggtc gcctgctgga
    28081 catggcccgc aaggagcccc aacagtatgc cgagcgagct gcggactcga tccgtcaggc
    28141 tctggcccgg cgcggcccgg aggctgggcg cagccacgct ctcgacagga tcggcctggc
    28201 agagtgccac ttcctcatgg gcgacgtcac cggggccgtg gagcacactc agcgcgccgt
    28261 cgaagcagcg gcccgtacca agtccagccg cgttcgggcg cagctcggcc agctgtatcc
    28321 gtacaccgtc ggcaggggcg cctcacggcc gacggccgag gcccggacaa tgatccgcga
    28381 catgctgtcg agctgaagga gcaacgtgac cacgatcgcc gtcaccgggc acatggacct
    28441 gaccgaggac agcgtgcccc tggtgcttga cgccctgcgg gagacgctga agccgtatgc
    28501 cgcagacctg accggtgtca cctgtattgc caagggagcg gactcgctgt ttgcggaggt
    28561 cgtgctggaa ctcggcggcc gtctgaccgc agtgatcccc tcacgggatt accggcggaa
    28621 caaggtcaag accgaccatg ccgacacgtt cgaccgcctc tccgaggccg cgggcgaggt
    28681 tctcgtcctg gagcacgaga cagcaaaccg gtcggcctac gaggacgcca accgcacgct
    28741 gctccagcgg gctgaccggc ttgtcgccgt ctgggacggc acgccgccgt ccgccaaggg
    28801 cggcggtacg gcggacacag tgctggaggc ccgcgacgcc gggctgcccg tcgacgtcat
    28861 ctggccggac ggggcagccc gccgcggctg agcacgccgg gtccaacacg cccgcgtacc
    28921 gcgcatgctt gaggatctcc atgtccgcga tctggaactg gatggcccgg taggcgccga
    28981 tcggccgccg aaggcctggc gttccttggc gtacttcacc gactagtcca cacagccctg
    29041 ctagaggccg gtctccaggg cggcgatggc gatgcggccc tcgtcccgga tgcgcaggaa
    29101 ccgggcgtag ccgcggccct cctcgccgag caggttggcg gcgggcacgc ggacgtcgaa
    29161 gggcatgctg ctcgcgctga gcgaggagta caccgaccac tacaccgacc actacacggt
    29221 ggacggtgac atcttcgacg agtgcactga catcgccctg accgcgttcc tgagcctggc
    29281 ggagcgcggt gacggagagt gcgggcaggc gtggcagaac tgggtcacca gggagggccg
    29341 ggagacgtac gcgtacatga cgctggacgc cctgctggcg gccatggccg tccactcgac
    29401 cgaggcggca caggacgacc gcacggtgct ggtacccgta cgggtgaccg atgtgctgcg
    29461 acgtgatcgg gcctactaca acaggtactt acgacgcgcc ctccccaacc cccttcggga
    29521 tgccaagcag ttggtgctgt tctcgaacat ccccatcacc gactccaggg ccctcggcga
    29581 ggccatgcac tgtctccaac agtggtgcag caaggggagc ctcgcccgcg tctactcggc
    29641 tatcaactca ggaggatgac cagattggac agcgcgatcg aagtggagcg aaagaggcag
    29701 ctgccggacg acggcaggca gttggcgctc ctgctcggtg agctcggctg gaagccgact
    29761 cacccgctga ccgaggtgga cacgtactac agccgcccgg acatcgacta catggcgacc
    29821 gtggagtgtc tgcgggtgcg gcgccggggt gacttcgcgg agatcaccta caagccgccg
    29881 tccaccgcgg tcacacacag cgccaacggc gtgatctcga agcaggagac caacgtccac
    29941 ctcgactcgg cgagccaggc cgcgctcgcg gaccagctgc tggagtacat cggcatgcgg
    30001 cccctggtcc gcgtggagaa gaaccggacg acgtaccacc acccgacgca gcccggcgtc
    30061 accgtcagca tcgacatggt ggccggtgtc ggggcgttcg tggagacgga ggtcatcagc
    30121 accgatgtga cgctggcaac cctgaaggtg gagcagaccg agaaccagct cggcatcacg
    30181 gacctgcccc cggtcgatct gccgtacagg gacctcgcgc ttacccgggc tcccgcgtga
    30241 gcggactacg cagagcccac gacaggagtg aggggagcgg aagagggtga ggcgcggcgt
    30301 cggccttcga cgcatcagca cgtcttgaag gccgacgccg cgccacgtct cagctcacct
    30361 tgatggtggc cttccacggc gcgatggcga gggggcactt gtacccaggg tcagggtggc
    30421 actgccgcac agcggagacg gtgctcgtgc ccgggctttc cgcgtgcagg accgcgtatg
    30481 cgtcaccggc cggtgtcgta ccgctgacag tccgggccag gacgtgggca tcgcgggtgc
    30541 tcggcatgct ccacgtgtac gtcaagcccc gctcgcggga ggccttcagc cggatctcgg
    30601 tgtcgtcacc gaccgaccgg gccacggtgc ggccgttgtc ggagttggtg aggacgaggc
    30661 ggtcggcccg agcggagtgc ggcgcggcgg aagcggccgg ggtgaccagc gtggcggtca
    30721 ccatcagtcc caacgtcaat ccggtcgcat acttcgcggc tttcacggtt acctccaggc
    30781 agatgacgga cgcgctgatc aacgtcccgc acgcccgtca cgcaatgccc tgccccgaga
    30841 gaaccacctg attcgccgaa cagcgcccct gtacccctag ctcaccaatc ccagttcccg
    30901 cgcgatcagc atccgctgga cctcgctcgt gccctcgccg atctccagga tcttggagtc
    30961 gcgccacatg cgggccaccg ggtactcgtt catgaagccg tagccgccgt ggatctgggt
    31021 ggcgtcgcgg gcgttgtcca cggcgatggt ggaggagtac agcttggcca gggccgcctc
    31081 cttcttgaag ggttcgccgg ccaccaggcg gctcgccgcg tcgcgccagg ccaggcgggc
    31141 cgtgtacgcc ttcatctcca tgtcggcgat cttgaactgg atggcctggt tggcaccgat
    31201 gggcttgccg aaggcgtggc gttccttcgc gtacttcagc gactcgtcga cgcagccctg
    31261 cgccaggccc gtcgcgaggg ccgcgatggc gatgcggccc tcgtcgagga tgcgcaggaa
    31321 ctgggcgtag ccccggccct cctcgccgag cagattggcg gcggggaccc ggacgtcggc
    31381 gaacgacagc tcgcgggtgt cggaggcgtt ccagccgacc ttcgagtagg gagccgccac
    31441 cgtgaagccg ggggtgcccg acgggacgat gatggacgag atctccggcc tgccgtccgg
    31501 cttgcggccc gtcaccgccg tgaccgtcac caaacccgtg atgtccgtac ccgagttggt
    31561 gatgaagcac ttcgtgccgt tgatcaccca ttcgttcgtg tccgggtcca gccgggccgt
    31621 cgtacgggtc gcgcccgcgt cgctgccgcc gtccggttcc gtcaggccga acgcgcccag
    31681 gatctcgccc gtgcacaggc gcgggagcca ctcgcgcttc tgctcctccg tgccgaacag
    31741 gtgcagcggc atggcgccca gggagacgcc cgcttcgagg gtgatcgcca cggacgagtc
    31801 gactctcgcc aactcctcca gggcgacgcc gagcgccaga tagtcgccgc ccatgccgcc
    31861 gtactcctcc gggaacggca gcccgaacag gcccatacgg cccatctcgc ggacgatctc
    31921 gtacgggaac tcgtgccgct cgtagaagtc gccgatcttc ggcgccacga catcgtgcgc
    31981 gaactcctcc accgtacggc ggagttcctc cagctcgggg ctgagacggt ggtccatgct
    32041 gatcactggt ccttgtggga gagagcgcgg acggtacggg acgggctggg ccggtccaga
    32101 tgggcggcca tccacacgct ggtggcggtc agacggccga ggtcgacccc ggtctcgatg
    32161 ccgaggccgt gcagcatcca gacgaggtcc tcggtggcga ggttgccggt ggcggacttg
    32221 gcgtacgggc agccgccgag gcctccggcc gaggcgtcga cggtggtcac gccgtgctcc
    32281 agggccgcgt aggtgttcgc gagcgcctgg ccgtaggtgt cgtggaagtg gacgccgatc
    32341 atgttcgtcg gcacgcgctc ctcgttgagg agggagagca gttcgagcac gtggcccggc
    32401 gttgcgactc cgatggtgtc gccgaggctc agctcgtcgc agcccatgtc gcgcagggcc
    32461 gtgcagacgc gggccacctg gtggagcggg accgcaccct cccaggggtc gccgaagcac
    32521 atggacacat agccgcgtac gtgcgcgccc gcgtccttgg cctgccggac caccggcgcg
    32581 aacacggcca gcgactcgtc caccgtgcgg ttgaggttgg ccttcgcgaa ggactcggtg
    32641 gcgctggcga agacggcgac ccggtcggcg ccgagcgcca gcgcccggtc caggccccgc
    32701 tggttgggc
//
