LOCUS       NZ_CM002285            42066 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4676300
            Orig. end                         :: 4718366
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..42066
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="arylpolyene"
                     /product="lassopeptide"
                     /region_number="27"
                     /rules="(APE_KS1 or APE_KS2)"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..42066
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="neighbouring"
                     /product="arylpolyene"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..41122
                     /SMILES=""
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41122
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21122](+)"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21122
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     assembly_gap    919..1491
                     /estimated_length=573
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            1557..1853
                     /gene="tatA"
                     /locus_tag="M878_RS69825"
                     /old_locus_tag="M878_21455"
     CDS             1557..1853
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0043953 - protein transport by the Tat
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="tatA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143938.1"
                     /locus_tag="M878_RS69825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21455"
                     /product="Sec-independent protein translocase subunit TatA"
                     /protein_id="WP_023548465.1"
                     /transl_table=11
                     /translation="MLRNGLEPWHLLIVAIVIIALFGSKKLPEAARGLGKSLRILKSET
                     KAMREDSVIQPSAAPTGDAPTDPAPTDPALRVIQAPPGETGTARPATENHAAG"
     misc_feature    2600..2614
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 23.96"
                     /tool="antismash"
     gene            2643..>2861
                     /locus_tag="M878_RS000000100010"
                     /pseudo=""
     CDS             2643..>2861
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013786.4"
                     /locus_tag="M878_RS000000100010"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSHSGDAVLFAVASSAVGADVEAPSARHGRFDLSSYLHPAEQRAL
                     QALDPAERTAALLGCWVRKEAYLKGVGS"
     gene            complement(3093..3614)
                     /locus_tag="M878_RS000000100015"
                     /old_locus_tag="M878_21470"
     CDS             complement(3093..3614)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602131.1"
                     /locus_tag="M878_RS000000100015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21470"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_245238155.1"
                     /transl_table=11
                     /translation="MSVLPVACPPVLTWARSLAAEHGSSKGSFYWFFANRDALIRAALQ
                     HWRCATTDQVAASPAELPDPAAKMTALLEYVFDSPFRGIGIALQADAVRPEVREVLAET
                     HRRRPDILRHLLTEAGLHLPEAESTALSLHAVHLGVLRLRCIDPELVPPGADGGDFQRT
                     VRDRLLPTLG"
     misc_feature    complement(3854..3869)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            3894..5624
                     /locus_tag="M878_RS69835"
                     /old_locus_tag="M878_21475"
     CDS             3894..5624
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075729.1"
                     /locus_tag="M878_RS69835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21475"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_031225348.1"
                     /transl_table=11
                     /translation="MFALWTWSGRAVGAAPPVGDVETVALVVPTSDLGGFEVSDVDCAL
                     IEPDRLAGAPLDSPGRSVDVWRARIAGGDPALPIAAHAVPDATGVAVTSAEHAVAVFHH
                     THAVATELRTALTAELRPYQVRGVSWLRETVDAHGGAVLADEMGLGKTLQTIGYIAGRA
                     KEGPQLVVCPTSLVGNWAHEIARFAPDLRTTIWRGGPLKEADSGTVVLTGYPTLRIHSP
                     AMTEHQWITAVFDEAQVLKNPRTQVSKAARAIAADARIALTGTPVENHLEELWALLNLV
                     APQLFGHKTQFRRRFVRPIANGSLAAAARLRGAIEPVVLMRKKSQVASSLPPKIHADLI
                     CDLTEEQQQVYDRLLEQAIDDGFGSGARRQTKVLAALTALKQVCNHPGLITGDLDELSG
                     RSGKLDLCTDIVANNLEIGSPTLIFTQYRQTGELLVRHCGEQFGVGVPFFHGGLNQKQR
                     ADIVRRFQADNGPKVLVLSLKAGGTGLTLTRAADVIHFDRWWNPAVEAQASDRVHRIGQ
                     TRTVTVTTLTTGTTVEEHIAAMHSRKSALSDIADMSGVAELARLDDDRLIAILRRKRDS
                     "
     gene            5628..6188
                     /locus_tag="M878_RS69840"
                     /old_locus_tag="M878_21480"
     CDS             5628..6188
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075728.1"
                     /locus_tag="M878_RS69840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21480"
                     /product="SWIM zinc finger-containing protein"
                     /protein_id="WP_023548474.1"
                     /transl_table=11
                     /translation="MSGNNFGHTLWGKDWVRFAEPLRQTRPDPQLPRARRIARDGKVQV
                     TIDGRIVRAVVQHGRNAAVANIEVAPMSREAMAGIARQLCGVRLVLTDELYRATADAGH
                     RPAPKLVGVDCSCSADTPRCIHVLAVYYEMARNIDDDPRISLDIQGFFRASSDSTEVST
                     AVTPQRWIALNALNPADYFMVST"
     gene            complement(6364..7224)
                     /locus_tag="M878_RS69845"
                     /old_locus_tag="M878_21485"
     CDS             complement(6364..7224)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (12-279). E-value: 1.6e-49. Score:
                     161.0. Matches aSDomain:
                     nrpspksdomains_M878_RS69845_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.4"
                     /locus_tag="M878_RS69845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21485"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_063750623.1"
                     /sec_met_domain="TauD (E-value: 2.4e-47, bitscore: 161.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGATTVSKSSISDGFGTEYRGLTAEALTDATTVSDVVDALETSHL
                     VVIRQTPLSPEQQIEFARKIGQPVPFNISRYRHPDYPELMISSNVVKDGKPIGVARVGN
                     FWHQDSTYLPDPPEYTLLQGVQVPEGHGDTLFASAINVLEALPADLREKAGQATATHLH
                     SRRFRMRPEHVGLSLPEFRAAVDKEYPPAVHPLTPVDEPTGQRYAYGSSGYTEAVDQFD
                     ANDNKRWFGAIEEFLGNPENIYRHKWTQGDLVMWKTKIAFHSATELPEGAGRIVHRVSI
                     RKSNR"
     aSDomain        complement(6388..7188)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69845_TauD.1"
                     /evalue="1.60E-49"
                     /label="M878_RS69845_TauD.1"
                     /locus_tag="M878_RS69845"
                     /protein_end="279"
                     /protein_start="12"
                     /score="161.0"
                     /tool="antismash"
                     /translation="DGFGTEYRGLTAEALTDATTVSDVVDALETSHLVVIRQTPLSPEQ
                     QIEFARKIGQPVPFNISRYRHPDYPELMISSNVVKDGKPIGVARVGNFWHQDSTYLPDP
                     PEYTLLQGVQVPEGHGDTLFASAINVLEALPADLREKAGQATATHLHSRRFRMRPEHVG
                     LSLPEFRAAVDKEYPPAVHPLTPVDEPTGQRYAYGSSGYTEAVDQFDANDNKRWFGAIE
                     EFLGNPENIYRHKWTQGDLVMWKTKIAFHSATELPEGAGRIVHRV"
     gene            complement(7367..8959)
                     /locus_tag="M878_RS69850"
                     /old_locus_tag="M878_21490"
     CDS             complement(7367..8959)
                     /NRPS_PKS="Domain: AMP-binding (23-421). E-value: 5.3e-105.
                     Score: 343.3. Matches aSDomain:
                     nrpspksdomains_M878_RS69850_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140387.1"
                     /locus_tag="M878_RS69850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21490"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_245238157.1"
                     /sec_met_domain="AMP-binding (E-value: 8.1e-112, bitscore:
                     372.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRNTAAAQKKSALTGSVAAVLADTAVRRPAHPALIHESEHFGYA
                     WLWERARRYARVLRENGVRPGDGVAMLVVDDPQFPLVYFGVLAAGAVVIPLNVRSTAAE
                     ITHVLTDADMRFLVCADSLIGPAREAAQPLGTLLLTVGTPQEGAVDLEEAARHTAPLDD
                     FVAREPDDAAVVFYTSGTTGKPKGVTLTHRNILHNVHTMAATPFAFRSDDVLLGGLPLP
                     HSFGQICSMLTGFHAGITMVMMPRFSGAEALKLMQEHRCTVFMGVPTMYFGLLDAVDKG
                     GAVPRIDRLYSGGSALPVKTFHDVQRVFACPVYEGYGLTETSTSVSYNHPGIVCRPGTV
                     GVPLDNVTVGIARPNTAGIELLPVGETGEIVVRGDNVMAGYLGRPDITAEVIVDGWFRS
                     GDLGRLDEDGYLSVVGRKKDLILRGGYNVYPREIEEALVGHPAVSQVAVIGVPHPVLGE
                     EVWAVVVPSRPEEATPEVGDKIVEWGRQRFASYKYPRRVEFAETLPLGPSGKVLKRTLV
                     AQLVSTVAPDSAG"
     CDS_motif       complement(7658..7720)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS69850_0003"
                     /evalue="1.50E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="M878_RS69850"
                     /protein_end="434"
                     /protein_start="413"
                     /score="11.4"
                     /tool="antismash"
                     /translation="VGRKKDLILRGGYNVYPREIE"
     aSDomain        complement(7697..8890)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69850_AMP-binding.1"
                     /evalue="5.30E-105"
                     /label="M878_RS69850_AMP-binding.1"
                     /locus_tag="M878_RS69850"
                     /protein_end="421"
                     /protein_start="23"
                     /score="343.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DTAVRRPAHPALIHESEHFGYAWLWERARRYARVLRENGVRPGDG
                     VAMLVVDDPQFPLVYFGVLAAGAVVIPLNVRSTAAEITHVLTDADMRFLVCADSLIGPA
                     REAAQPLGTLLLTVGTPQEGAVDLEEAARHTAPLDDFVAREPDDAAVVFYTSGTTGKPK
                     GVTLTHRNILHNVHTMAATPFAFRSDDVLLGGLPLPHSFGQICSMLTGFHAGITMVMMP
                     RFSGAEALKLMQEHRCTVFMGVPTMYFGLLDAVDKGGAVPRIDRLYSGGSALPVKTFHD
                     VQRVFACPVYEGYGLTETSTSVSYNHPGIVCRPGTVGVPLDNVTVGIARPNTAGIELLP
                     VGETGEIVVRGDNVMAGYLGRPDITAEVIVDGWFRSGDLGRLDEDGYLSVVGRKKDLI"
     CDS_motif       complement(7787..7873)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS69850_0002"
                     /evalue="2.00E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="M878_RS69850"
                     /protein_end="391"
                     /protein_start="362"
                     /score="33.0"
                     /tool="antismash"
                     /translation="PVGETGEIVVRGDNVMAGYLGRPDITAEV"
     CDS_motif       complement(8384..8443)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS69850_0001"
                     /evalue="2.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="M878_RS69850"
                     /protein_end="192"
                     /protein_start="172"
                     /score="25.9"
                     /tool="antismash"
                     /translation="AVVFYTSGTTGKPKGVTLTH"
     gene            complement(9009..10238)
                     /gene="hemA"
                     /locus_tag="M878_RS69855"
                     /old_locus_tag="M878_21495"
     CDS             complement(9009..10238)
                     /EC_number="2.3.1.37"
                     /GO_function="GO:0003870 - 5-aminolevulinate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006783 - heme biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (49-390). E-value:
                     6.1e-78. Score: 254.4. Matches aSDomain:
                     nrpspksdomains_M878_RS69855_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="hemA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566618.1"
                     /locus_tag="M878_RS69855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21495"
                     /product="5-aminolevulinate synthase"
                     /protein_id="WP_023548480.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.3e-76, bitscore:
                     254.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.1e-05,
                     bitscore: 21.0, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 2.1e-06, bitscore:
                     25.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHLESYPKGTTGAASSGRRIEHMQVGRRFGMFPQATASQDGVD
                     SQIQVWCSNDYLGMGQNPRVAEAMKAAIDNHGVGSGGSRNIGGTNQFHVLLEAELADLH
                     GKEAALIFASGYTANDGALTVLAGTPKDTIVFSDARNHASIIDGIRHSGAEKYIYRHND
                     VAHLEELLAAAPADRPKLIAMESVHSMLGDIAPVAEISELASRYGATTYIDEVHAVGMY
                     GPQGAGIAAREGLADKFTVVMGTLGKGYGVMGGYITGPAALIDTVRTLSRSFIFTTSLP
                     PAIAAGALESVRHLRASEAERTALSENARLLHRLLGEAGIPCLSTDSHIVSALVGDSEA
                     CRRASEMLLDRHGIYVQSIASPDVPAGEELLRITPSPVHDPKDVENLAHVLGGIWKELD
                     IATASDRHGA"
     aSDomain        complement(9069..10091)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69855_Aminotran_1_2.1"
                     /evalue="6.10E-78"
                     /label="M878_RS69855_Aminotran_1_2.1"
                     /locus_tag="M878_RS69855"
                     /protein_end="390"
                     /protein_start="49"
                     /score="254.4"
                     /tool="antismash"
                     /translation="VWCSNDYLGMGQNPRVAEAMKAAIDNHGVGSGGSRNIGGTNQFHV
                     LLEAELADLHGKEAALIFASGYTANDGALTVLAGTPKDTIVFSDARNHASIIDGIRHSG
                     AEKYIYRHNDVAHLEELLAAAPADRPKLIAMESVHSMLGDIAPVAEISELASRYGATTY
                     IDEVHAVGMYGPQGAGIAAREGLADKFTVVMGTLGKGYGVMGGYITGPAALIDTVRTLS
                     RSFIFTTSLPPAIAAGALESVRHLRASEAERTALSENARLLHRLLGEAGIPCLSTDSHI
                     VSALVGDSEACRRASEMLLDRHGIYVQSIASPDVPAGEELLRITPSPVHDPKDVENLAH
                     V"
     misc_feature    complement(10428..10444)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 24.15"
                     /tool="antismash"
     gene            complement(11126..12682)
                     /locus_tag="M878_RS69860"
                     /old_locus_tag="M878_21500"
     CDS             complement(11126..12682)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603446.1"
                     /locus_tag="M878_RS69860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21500"
                     /product="MFS transporter"
                     /protein_id="WP_051430097.1"
                     /transl_table=11
                     /translation="MTTPPTLPKSRQQLILAVLLLSSLLIWLDNTILTTAFETLADPVR
                     GLGASPSQLQWATGSYTLVFATLMFTSGALGDRFGHRTVLATGMAVFAGASVWAAYAGD
                     ADQLIAARAAMGMGSALIMPAQVAILMWTFSGPARATAIGISSTSAGVGIAAGPLLAGV
                     LLGHFWWGSIFLVNIPIAVLSLIGIATLVPNFRSPTPRPLDPAGLLLSISGLAFLAYGL
                     IRAGQVASWSPVSVWGPIAAGVVLLTGFVLVELRHRQPSFDPRLLAQRMFGLANVALGL
                     LMFAMTAASFYGAFYLQGAREFSPLQAGLAFSPTALGAIVGAPLGVRLARRWTLRVVTA
                     TALTTAGLAMGCNMLFGLHTPLVFNEIAYMIQGLSIGMVIGPVTGGLMSVLPLERAGAG
                     SAVLNTVRQTGSLMGIAVGGTIMSLAYRHAVDSSLSGYPEQVQARARISAEQARHAAAA
                     IHQPDLVRVANDAFIKAMHISAAGTMLIALCGALLLVIALRPDRQPAEPVVQDNRVKSN
                     L"
     gene            12901..14541
                     /locus_tag="M878_RS69865"
                     /old_locus_tag="M878_21505"
     CDS             12901..14541
                     /NRPS_PKS="Domain: AMP-binding (47-451). E-value: 2.4e-67.
                     Score: 219.2. Matches aSDomain:
                     nrpspksdomains_M878_RS69865_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139179.1"
                     /locus_tag="M878_RS69865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21505"
                     /product="AMP-binding protein"
                     /protein_id="WP_280923667.1"
                     /sec_met_domain="AMP-binding (E-value: 9.1e-68, bitscore:
                     227.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRQDRIAPGPADRDPPGYVSRGRVMTPQDQWWRESDSYVSDILS
                     VFAAAPDRPAIFWRGRAFSGGELIRSTTEIFHALRDRGVGEEDVVAILVAPNSPEMLTA
                     RYAAHLLGSTVCYLRSTNPGTSSTILPLDHQIQILRDTAASTVYADAENAQRALELSEG
                     IGGLPVTRVDGTGHDAASRADAPQAAPWDPSTVGVIGFTSGSTGRPKGIRLSGQVWNGG
                     VRGMVAADRAAEDVRLLVTTPLSHTVGTMADAALALGGEVHLHEHFDAGQFTKTVEESA
                     ISWTFMATVQLFQLLDHLEELGAHDLESAGLSSLKRLIYSGSAAAPARIAQAVRILGLI
                     LVQAYGTSESGRITSLKREEHLDPWLSTTVGRPFGEVEVVVGDLVSGAPVPTGEVGQVR
                     VRSPHLMDGYTGDPELTAQVLRDGWYYTGDIGYCDEKGYLHLLGRVAEVVKVDGVKVHP
                     LVVEREILSLPGIRHAAVYGVQDRDGSEHIHAALVCDPAAEVETESIRTHIAESLSVLH
                     APEKITILSALPLNDNGKPDKLRLRLLEA"
     aSDomain        13042..14253
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69865_AMP-binding.1"
                     /evalue="2.40E-67"
                     /label="M878_RS69865_AMP-binding.1"
                     /locus_tag="M878_RS69865"
                     /protein_end="451"
                     /protein_start="47"
                     /score="219.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AAAPDRPAIFWRGRAFSGGELIRSTTEIFHALRDRGVGEEDVVAI
                     LVAPNSPEMLTARYAAHLLGSTVCYLRSTNPGTSSTILPLDHQIQILRDTAASTVYADA
                     ENAQRALELSEGIGGLPVTRVDGTGHDAASRADAPQAAPWDPSTVGVIGFTSGSTGRPK
                     GIRLSGQVWNGGVRGMVAADRAAEDVRLLVTTPLSHTVGTMADAALALGGEVHLHEHFD
                     AGQFTKTVEESAISWTFMATVQLFQLLDHLEELGAHDLESAGLSSLKRLIYSGSAAAPA
                     RIAQAVRILGLILVQAYGTSESGRITSLKREEHLDPWLSTTVGRPFGEVEVVVGDLVSG
                     APVPTGEVGQVRVRSPHLMDGYTGDPELTAQVLRDGWYYTGDIGYCDEKGYLHLLGRVA
                     EVVKV"
     CDS_motif       13495..13542
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS69865_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="M878_RS69865"
                     /protein_end="214"
                     /protein_start="198"
                     /score="17.8"
                     /tool="antismash"
                     /translation="IGFTSGSTGRPKGIRL"
     CDS_motif       14071..14154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS69865_0002"
                     /evalue="6.50E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="M878_RS69865"
                     /protein_end="418"
                     /protein_start="390"
                     /score="18.5"
                     /tool="antismash"
                     /translation="PTGEVGQVRVRSPHLMDGYTGDPELTAQ"
     gene            14595..15833
                     /gene="hemA"
                     /locus_tag="M878_RS69870"
                     /old_locus_tag="M878_21510"
     CDS             14595..15833
                     /EC_number="2.3.1.37"
                     /GO_function="GO:0003870 - 5-aminolevulinate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006783 - heme biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (49-391). E-value:
                     7.4e-75. Score: 244.2. Matches aSDomain:
                     nrpspksdomains_M878_RS69870_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="hemA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139180.1"
                     /locus_tag="M878_RS69870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21510"
                     /product="5-aminolevulinate synthase"
                     /protein_id="WP_023548486.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9e-73, bitscore:
                     244.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.6e-05,
                     bitscore: 21.0, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.5e-07, bitscore:
                     29.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHLESYSDGPIAADVAARRREFLEIARHSGKFPTATARQDGAD
                     LQISVWCSNDYLGMGENPKIIEAMTSAIQAHGVGSGGSRNIGGTNQYHVQLERELAELH
                     DKEAALLFTSGFTANDGALTVLAGLPKDTVVFSDAENHASIIDGLRHSGAQKHVFRHND
                     VAHLEELLAATPADRPKLIVLESVYSMSGDIAPLAEIAEVANRYNATTYLDEVHAVGMY
                     GPEGAGIAAREGIADQFTVIMGTLAKGFGTVGGYIAGPAALIEAVRTLSRGFIFTTSLP
                     PAIAAGSLTSVRHLRNSEVERQALAENAQLLHRLLDEADIPFISADSHIVCAFIGDDRT
                     CKQASSLLFKRHGMYVQPINAPSVPAGQEILRIAPSAVHTRSDVENFAEALRDVWKELD
                     IPSASDRLLAQQS"
     aSDomain        14742..15767
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69870_Aminotran_1_2.1"
                     /evalue="7.40E-75"
                     /label="M878_RS69870_Aminotran_1_2.1"
                     /locus_tag="M878_RS69870"
                     /protein_end="391"
                     /protein_start="49"
                     /score="244.2"
                     /tool="antismash"
                     /translation="VWCSNDYLGMGENPKIIEAMTSAIQAHGVGSGGSRNIGGTNQYHV
                     QLERELAELHDKEAALLFTSGFTANDGALTVLAGLPKDTVVFSDAENHASIIDGLRHSG
                     AQKHVFRHNDVAHLEELLAATPADRPKLIVLESVYSMSGDIAPLAEIAEVANRYNATTY
                     LDEVHAVGMYGPEGAGIAAREGIADQFTVIMGTLAKGFGTVGGYIAGPAALIEAVRTLS
                     RGFIFTTSLPPAIAAGSLTSVRHLRNSEVERQALAENAQLLHRLLDEADIPFISADSHI
                     VCAFIGDDRTCKQASSLLFKRHGMYVQPINAPSVPAGQEILRIAPSAVHTRSDVENFAE
                     AL"
     gene            16076..16816
                     /gene="fabG"
                     /locus_tag="M878_RS69875"
                     /old_locus_tag="M878_21515"
     CDS             16076..16816
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (5-161). E-value: 6.2e-25. Score:
                     80.1. Matches aSDomain:
                     nrpspksdomains_M878_RS69875_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374269.1"
                     /locus_tag="M878_RS69875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21515"
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="WP_031225354.1"
                     /sec_met_domain="adh_short (E-value: 9.2e-40, bitscore:
                     135.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGERGCAVVTGGSRGIGRAVAVQLAADGYDIAFCYRSGGDTAVQA
                     EKEIRDLGVECYHAPCDVTDLESVQAFLKTTEEKLGDIVALVNSAGIVKDNPMVLMPPA
                     DWHAVIDTNLSGTYNFCRSVVFGFMKRKAGTIVNISSVAGVFGNPTQANYSAAKSGIHG
                     MSKALAKEVAGYGIRVNVVAPGFIETDMTSELPEKARKTALGMIPMKRIGEPKDVSELV
                     SFLVSERAAYITGQVIQVDGGIVF"
     aSDomain        16091..16558
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69875_PKS_KR.1"
                     /evalue="6.20E-25"
                     /label="M878_RS69875_PKS_KR.1"
                     /locus_tag="M878_RS69875"
                     /protein_end="161"
                     /protein_start="5"
                     /score="80.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="CAVVTGGSRGIGRAVAVQLAADGYDIAFCYRSGGDTAVQAEKEIR
                     DLGVECYHAPCDVTDLESVQAFLKTTEEKLGDIVALVNSAGIVKDNPMVLMPPADWHAV
                     IDTNLSGTYNFCRSVVFGFMKRKAGTIVNISSVAGVFGNPTQANYSAAKSGI"
     CDS_motif       16097..16153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS69875_0001"
                     /evalue="3.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="M878_RS69875"
                     /protein_end="26"
                     /protein_start="7"
                     /score="16.3"
                     /tool="antismash"
                     /translation="VVTGGSRGIGRAVAVQLAA"
     CDS_motif       16487..16546
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS69875_0002"
                     /evalue="2.70E-09"
                     /label="PKSI-KR_m4"
                     /locus_tag="M878_RS69875"
                     /protein_end="157"
                     /protein_start="137"
                     /score="29.6"
                     /tool="antismash"
                     /translation="NISSVAGVFGNPTQANYSAA"
     gene            16816..17229
                     /locus_tag="M878_RS48360"
                     /old_locus_tag="M878_21520"
     CDS             16816..17229
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019589.4"
                     /locus_tag="M878_RS48360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21520"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_023548490.1"
                     /transl_table=11
                     /translation="MPEARRRAAPLDAVDDIVQVSDSEITATKSVHAGDPYLEGHYPDF
                     TIYPGVFIMESVNQTVDAYVARTFGADRIADLTTVTSARFTSPVLPGDTLQVSCKLVVQ
                     GDDLAVDANCRNALGEAAARLKLVYRITDGGIR"
     gene            17226..17702
                     /locus_tag="M878_RS69880"
                     /old_locus_tag="M878_21525"
     CDS             17226..17702
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270: UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019589.4"
                     /locus_tag="M878_RS69880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21525"
                     /product="hypothetical protein"
                     /protein_id="WP_023548491.1"
                     /transl_table=11
                     /translation="MIDHAGIRNIIPHRHPVLLVDAVLELSPFDRIVTVKAISGSEPCY
                     ARMAEGLGSSAFAYPKPLLIESFAQSGAVLWLESIKSRGESLNGTLIFAAARNVEFHRP
                     VYPGDTVRHTLKIDQLVGNNAFLSGRSFVGDEPVMTVAEAIAVVRPNEGIARRA"
     gene            17806..18066
                     /locus_tag="M878_RS69885"
                     /old_locus_tag="M878_21530"
     CDS             17806..18066
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (10-76). E-value: 6.2e-14.
                     Score: 44.1. Matches aSDomain:
                     nrpspksdomains_M878_RS69885_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540283.1"
                     /locus_tag="M878_RS69885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21530"
                     /product="acyl carrier protein"
                     /protein_id="WP_023548493.1"
                     /sec_met_domain="PP-binding (E-value: 3.6e-12, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAINQQLMDELREMIAEVLEEEPENITETSLFIEEHEADSLRA
                     IEILARIEKKYKVSLPQELLADMVNLRAVYNTVVEYSDGNL"
     aSDomain        17836..18033
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69885_PP-binding.1"
                     /evalue="6.20E-14"
                     /label="M878_RS69885_PP-binding.1"
                     /locus_tag="M878_RS69885"
                     /protein_end="76"
                     /protein_start="10"
                     /score="44.1"
                     /tool="antismash"
                     /translation="DELREMIAEVLEEEPENITETSLFIEEHEADSLRAIEILARIEKK
                     YKVSLPQELLADMVNLRAVYN"
     gene            18068..>18298
                     /locus_tag="M878_RS48365"
                     /pseudo=""
     CDS             18068..>18298
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS48365"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRRVVITGLGPLSTIGVGPDAFAAGLRAGASNSGPIRSFDASGF
                     PHNIANELGDVHPSDYVTNIDPEAWGPASLAA"
     assembly_gap    18299..19032
                     /estimated_length=734
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            <19033..19995
                     /locus_tag="M878_RS69890"
                     /old_locus_tag="M878_21540"
     CDS             <19033..19995
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (1-317). E-value:
                     1.3e-52. Score: 171.0. Matches aSDomain:
                     nrpspksdomains_M878_RS69890_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hr-t2pks-ksa"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266163.1"
                     /locus_tag="M878_RS69890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21540"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_023548499.1"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 3.1e-88, bitscore:
                     295.4, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.3e-25, bitscore:
                     88.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LAVDDAGLDRAELRRGRAGSVFGTTGGETRLHEDAYERWLAEGPA
                     ADFSDLVPKIPAYRLAVAANRELGIDGEAVTLATACSASNYAIGYAYDMIAGGDSDYMI
                     AGGSEAMCAFAVAGFYRLGALAKDVCTPFDANRKGILIGEGSSALLLESLDSALARGAR
                     IYAEVLGYGLNCDANHMVSPLATSIAECTRRAHENAGVKKDEIDYVCAHGTGTPSNDSA
                     EVAAMREVFGDQLPPMSSIKSMLGHSMGAASGFGAIACCLAIRDGFIPPTINLNTLDPN
                     FEGIDVVPNVSRDADVRIVQNNGFAFGGNNAITIFGRYE"
     aSDomain        19039..19986
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69890_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.30E-52"
                     /label="M878_RS69890_PKS_KS.1"
                     /locus_tag="M878_RS69890"
                     /protein_end="317"
                     /protein_start="1"
                     /score="171.0"
                     /tool="antismash"
                     /translation="AVDDAGLDRAELRRGRAGSVFGTTGGETRLHEDAYERWLAEGPAA
                     DFSDLVPKIPAYRLAVAANRELGIDGEAVTLATACSASNYAIGYAYDMIAGGDSDYMIA
                     GGSEAMCAFAVAGFYRLGALAKDVCTPFDANRKGILIGEGSSALLLESLDSALARGARI
                     YAEVLGYGLNCDANHMVSPLATSIAECTRRAHENAGVKKDEIDYVCAHGTGTPSNDSAE
                     VAAMREVFGDQLPPMSSIKSMLGHSMGAASGFGAIACCLAIRDGFIPPTINLNTLDPNF
                     EGIDVVPNVSRDADVRIVQNNGFAFGGNNAITIFG"
     cand_cluster    19855..42066
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    19855..42066
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[29854:32066](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(29855..32066)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="2"
     gene            20001..21122
                     /locus_tag="M878_RS69895"
                     /old_locus_tag="M878_21545"
     CDS             20001..21122
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (66-331). E-value:
                     2.7e-08. Score: 25.0. Matches aSDomain:
                     nrpspksdomains_M878_RS69895_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012337.4"
                     /locus_tag="M878_RS69895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21545"
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_245238402.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-17, bitscore:
                     63.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="APE_KS1 (E-value: 7.1e-30, bitscore:
                     103.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTGWGVLSAIGTGAEEFSEAWGERRSGRKDVTEMFEQKLPSET
                     ACAIPDFDVKAHLGRKGTSFFDRSTALSVVTCKLALEDAGLVRDAKDEETDGGIGLVLG
                     LSSGGPQAMSDFIHEMYTSEKPYLVNPLLFPYAVMNGAASATAIWHNLKGVNATVSGGQ
                     MAFLTALRYARNKVRSGYVNAAVAGAVEEFSPTRAWASHQARGAGEERVDLGEGGAFFV
                     LEDAQTVRTAGRGLDAEILAVECGLYGEPGSKDDPAVGMTECIIRALEAAGVAASDVWA
                     VAPSLSGSPKRDRIERVAITAALGTDTPNLLPVKELVGETYSAAGGLQLAALLAEHRRN
                     PERDGAVSLVTSLTSEGMVGVAVVRGWSRATSA"
     aSDomain        20199..20993
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69895_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="2.70E-08"
                     /label="M878_RS69895_PKS_KS.1"
                     /locus_tag="M878_RS69895"
                     /protein_end="331"
                     /protein_start="66"
                     /score="25.0"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="DRSTALSVVTCKLALEDAGLVRDAKDEETDGGIGLVLGLSSGGPQ
                     AMSDFIHEMYTSEKPYLVNPLLFPYAVMNGAASATAIWHNLKGVNATVSGGQMAFLTAL
                     RYARNKVRSGYVNAAVAGAVEEFSPTRAWASHQARGAGEERVDLGEGGAFFVLEDAQTV
                     RTAGRGLDAEILAVECGLYGEPGSKDDPAVGMTECIIRALEAAGVAASDVWAVAPSLSG
                     SPKRDRIERVAITAALGTDTPNLLPVKELVGETYSAAGGLQLA"
     aSDomain        21199..21510
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS69900_Abhydrolase_1.1"
                     /evalue="8.30E-14"
                     /label="M878_RS69900_Abhydrolase_1.1"
                     /locus_tag="M878_RS69900"
                     /protein_end="104"
                     /protein_start="0"
                     /score="43.7"
                     /tool="antismash"
                     /translation="MVMLHGLEDDWQSWKPMADRLGDRFHCYAIDLPWRAGGGYEWRAG
                     GTAAQWVENALALIPQPISVLVAHSMGANAVLHWLASGTPRRVDALVLLSPFYRLASAP
                     "
     gene            21199..21963
                     /locus_tag="M878_RS69900"
                     /old_locus_tag="M878_21550"
     CDS             21199..21963
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (0-104). E-value: 8.3e-14.
                     Score: 43.7. Matches aSDomain:
                     nrpspksdomains_M878_RS69900_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="M878_RS69900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21550"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_051430098.1"
                     /sec_met_domain="PF00561 (E-value: 6.1e-09, bitscore: 34.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.7e-16, bitscore:
                     60.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMLHGLEDDWQSWKPMADRLGDRFHCYAIDLPWRAGGGYEWRAG
                     GTAAQWVENALALIPQPISVLVAHSMGANAVLHWLASGTPRRVDALVLLSPFYRLASAP
                     VDWAMFDRSLADFRTVMAAGLRARLGERAERLEPEIVSLMAEKALDRIGPEGFLSLFDI
                     FISSSGIDLSSNTVPTLVVGGSADPGISGPRAEALGRDMPTAEIRLEDELTHFCHIEQP
                     QRVSELVSEFLLRRLPAALEGGRRPALEGVHL"
     misc_feature    21241..21256
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.15"
                     /tool="antismash"
     gene            21960..22598
                     /locus_tag="M878_RS69905"
                     /old_locus_tag="M878_21555"
     CDS             21960..22598
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013488.4"
                     /locus_tag="M878_RS69905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21555"
                     /product="DsbA family protein"
                     /protein_id="WP_023548505.1"
                     /transl_table=11
                     /translation="MSNRYPPKFYFSLHSPYSWMASRLLAERCPDALESMQWIPYFYPD
                     EQTWKSMAERGIELHYADMSKAKHLYILQDVKRLSARFGFDMAWPVDREPWWVLPHHAW
                     LAAKRTGDQNALYWALVEARWGRGENICDRETVRKIADAAGLDGEALSAAPEDPELREE
                     GMAAQEAAYLDDVFGAPYFKIGPQRYWGLDRLDDFIAGFRQWQQKGKAA"
     gene            22595..22768
                     /locus_tag="M878_RS97605"
                     /old_locus_tag="M878_21560"
     CDS             22595..22768
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS97605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_21560"
                     /product="hypothetical protein"
                     /protein_id="WP_023548508.1"
                     /transl_table=11
                     /translation="MTTQPNADRTPEAESLTGLRRPVPVVLDIDDDPMEGIPAELVDMV
                     GQFDRDTAGGCG"
     gene            22768..24201
                     /locus_tag="M878_RS69910"
                     /old_locus_tag="M878_21565"
     CDS             22768..24201
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359039.1"
                     /locus_tag="M878_RS69910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21565"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_023548510.1"
                     /sec_met_domain="Aldedh (E-value: 1.6e-157, bitscore:
                     523.8, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASVPAQTHWIDGAWTTGHTRWIDVVDPTTEERLAAVPAGTTADA
                     ELAVAAAAKAFGHWSAVPLEDRVAAVRAVAKGLSARHDEIAATITAEVGVPTWFSQRVQ
                     ASLPAATSAAVAGIAEEFAWTEQIGHSTVIREPVGVVAAITPWNFPLHQAVAKVVPALL
                     AGNTVVLKPSEIAPLTARFLAEVTREAQIPDGVLNIVHGEGPVVGEALATHPGVDMVSF
                     TGSTAAGKRVAALAAGTVKRVALELGGKSANLVLPDADLLAAVRAGVANCFMNSGQMCW
                     AWSRMLVPAALHSQAVEAAAAEAAAFTVGDPVQPDTRLGPLASAAQRDRVRGYIERGVA
                     DGAQLAAGGPTPPDGLDRGYFVRPTVFGGVDPTAVIAQEEIFGPVLSIIPYSSEDEAVE
                     IANATRYGLGGAVFSADPDHALAVARQLRTGQVDINGAAFNAVAPFGGYRQSGNGRELG
                     RFGLEEFCEVKSIQRSASV"
     misc_feature    24209..24225
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            24228..24881
                     /locus_tag="M878_RS48370"
                     /old_locus_tag="M878_21570"
     CDS             24228..24881
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471081.1"
                     /locus_tag="M878_RS48370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21570"
                     /product="response regulator transcription factor"
                     /protein_id="WP_023548512.1"
                     /transl_table=11
                     /translation="MPTRTLDDGIEIILMIRDDMRRYGVEGMFRSLDTPLTTHACTDFG
                     ELARFSNGQLIVSSDDVAGPISDETAGTLRAHGIRMLILVDSAAALDQSWADCAHGFLD
                     WADLRPESLRDAIADVASGRFHMSESLARRSVTAPEQAESDPTARRSSISLTARELQVL
                     RLIAGGLSNRQVARSLSISEHGVKRLVGIVLAKLNCPNRTLAVVRAIELGLLTL"
     gene            24913..25443
                     /locus_tag="M878_RS69915"
                     /old_locus_tag="M878_21575"
     CDS             24913..25443
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025196.4"
                     /locus_tag="M878_RS69915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21575"
                     /product="DUF4188 domain-containing protein"
                     /protein_id="WP_023548514.1"
                     /transl_table=11
                     /translation="MSQVHRGRHTAHIEGDFVVFLIGMHVNRPWRIHKWWPVFRSMFGM
                     IKDLREHPEKGALCSYFALISGVGPAVVQYWRSFEHLEAFARNTDDPHLPSWRRYNQRV
                     LKSGDVGIWHETYLVKDGQYETVYANMGRIGLARAGELKPVQAKGHTAGRRLGRTAEDD
                     FPDGTRPGGGSPS"
     gene            25607..26425
                     /locus_tag="M878_RS92300"
                     /old_locus_tag="M878_21580"
     CDS             25607..26425
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044908.1"
                     /locus_tag="M878_RS92300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21580"
                     /product="thioesterase family protein"
                     /protein_id="WP_023548516.1"
                     /transl_table=11
                     /translation="MNAATTSEALLPPIDRSWRTWAGALGGLVSTLMLRHAGDQLTVDL
                     APRALHSSFLAPVSDHPLLVRSEVVRQSRTSAVVRSTLEQHERPVALATALFGTIGDKP
                     TLQAAEAPVVPSPEDCPDAGFPARMFPYAAHFETRMAGEERPFGGGTHPEMTAWLRLRE
                     PDLPIAAAALVLLDAMPPAVYAAASELVAVPTAEYSVHFTDGLSFAESGDWALVRVGTD
                     QSSDRWTVESSSLWNADGTLLAVGRQTRQFLRPTAPGSALKVPPTWWQRA"
     gene            complement(26538..27308)
                     /locus_tag="M878_RS98930"
                     /old_locus_tag="M878_21585"
     CDS             complement(26538..27308)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061568.1"
                     /locus_tag="M878_RS98930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21585"
                     /product="response regulator transcription factor"
                     /protein_id="WP_023548518.1"
                     /transl_table=11
                     /translation="MGEFLLAPSGTHQVTRAEILSGVEQGRLIEQFDNADEMRISALQS
                     VMRARYDVMISALKSEWYSSERRRTVQKIVGDAARRRVAVRELYRCDDLPSWCTPDYLL
                     SAAECGIRVRVTDTKLQELVIVDSQVAFMRTQVSLSQEQCLAIWAPPVIKNLQSLLTAV
                     WNGASEPVSYLRYPRSEFDEADLQIVNELAGGSKDEVAARRLGISLRTYRRRVAELMSR
                     LDANSRFQAGVHALRDGLLRRGGRDEELPYRYSA"
     gene            complement(27412..27780)
                     /locus_tag="M878_RS000000100025"
                     /old_locus_tag="M878_21590"
     CDS             complement(27412..27780)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024212.4"
                     /locus_tag="M878_RS000000100025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21590"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_280923686.1"
                     /transl_table=11
                     /translation="MRSAIAGELTAFGLSTSQYATLLMAEVRPGMSASDIAREVASSRQ
                     AANEMLVGLEQEGLIERRTNPSDRRSHQIFVTESGRTRLAAARKAVDRCEAELEAAFTP
                     EQRAAIREWLEGISAARR"
     gene            complement(<27946..>28098)
                     /locus_tag="M878_RS000000101050"
                     /pseudo=""
     CDS             complement(<27946..28098)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008745676.1"
                     /locus_tag="M878_RS000000101050"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS1380 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGVRKERPHPGVQLRIADADGLGITCLATSTPDRPIARLGLRHRS
                     GIEARA"
     gene            28268..28411
                     /locus_tag="M878_RS97610"
                     /old_locus_tag="M878_21595"
     CDS             28268..28411
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS97610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_21595"
                     /product="hypothetical protein"
                     /protein_id="WP_023548521.1"
                     /transl_table=11
                     /translation="MLSDNVTYRELGAYFTQRNPQRATRRAINALNQHGYTVTRNPRGA
                     TA"
     misc_feature    complement(28275..28287)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     gene            complement(<28463..>28570)
                     /locus_tag="M878_RS000000100030"
                     /pseudo=""
     CDS             complement(<28463..28570)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611183.1"
                     /locus_tag="M878_RS000000100030"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCGIVYVLHTGIR"
     gene            complement(28705..29277)
                     /locus_tag="M878_RS69925"
                     /old_locus_tag="M878_21600"
     CDS             complement(28705..29277)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471980.1"
                     /locus_tag="M878_RS69925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21600"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_023548523.1"
                     /transl_table=11
                     /translation="MTLPVLHPRPGNLREVAERIEASTGLRVEIIGGSLVMSPTPRGKH
                     AGTIRRLRVQIEPRLPGGLAPYEMSSVAMPEDPDDYATPDLTVLPVEWDEDDSWLADPG
                     DVALAVEVISQSEKAKDITDKNGWYARAGVAVLLVLDPRTGRWTLHTRPKGGEYCGQVH
                     GEYGEVVELPAPLPSPLDTGVLPRYGA"
     gene            complement(29855..30283)
                     /locus_tag="M878_RS69930"
                     /old_locus_tag="M878_21605"
     CDS             complement(29855..30283)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382052.1"
                     /locus_tag="M878_RS69930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21605"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_023548525.1"
                     /sec_met_domain="PF13471 (E-value: 2.4e-25, bitscore: 87.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVHTALPTADRPAWWRRPPIRLAITVAWLLSRLPPGRIRTILLL
                     VRRGARPATRGEAQRARTEITSLSLACAGEGCLQRSLATTLLCRMRGSWPTWCTGVRTQ
                     PFAAHAWVEVEAVPVDEDTAIAQYRRIMTVPPHHRQRV"
     gene            complement(30320..30580)
                     /locus_tag="M878_RS69935"
                     /old_locus_tag="M878_21610"
     CDS             complement(30320..30580)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033530.1"
                     /locus_tag="M878_RS69935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21610"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_023548527.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 1e-07, bitscore:
                     31.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.3e-21,
                     bitscore: 73.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1e-13, bitscore: 50.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFRLHRHVTAVTTDTGMVILDERTGGYFELNGTGSATLTALLNG
                     ASQEEAVHRLTAGTDATPAQAAADVNAFLADLARRGLGSLA"
     aSDomain        complement(30335..30577)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M878_RS69935_Stand_Alone_Lasso_RRE.1"
                     /evalue="2.00E-23"
                     /identifier="RREFam002.1"
                     /label="M878_RS69935"
                     /locus_tag="M878_RS69935"
                     /protein_end="82"
                     /protein_start="1"
                     /score="73.2"
                     /tool="antismash"
                     /translation="AFRLHRHVTAVTTDTGMVILDERTGGYFELNGTGSATLTALLNGA
                     SQEEAVHRLTAGTDATPAQAAADVNAFLADLARRGL"
     gene            complement(30582..32066)
                     /locus_tag="M878_RS69940"
                     /old_locus_tag="M878_21615"
     CDS             complement(30582..32066)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="M878_RS69940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21615"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_158692720.1"
                     /sec_met_domain="Asn_synthase (E-value: 5.2e-27, bitscore:
                     94.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHGITVAADRADILADLSGADLDERWLAVRLITGGPPHLLDGLTA
                     WQGVFAVPPGDALTVGAHGGSAHRPWWSPPLPDRPVETGAAALRAALAEAVALRIAQAP
                     ESAVGCDLSGGMDSTALAFLASAAGASLHTMTLAFRDPANDDTHWANLARSHLPDTVAL
                     SLADDELPGQYENLGEPGSPADAPSGVLRGRAVFDATAARYRGHGVVLQLAGHGGDEVL
                     QTPPGYLGDLLPAHPLLAVRHLRGHRSVRRWPLSLALRGLVDRRSYPQWLRDQARRLRG
                     GPPTEPSHHVPLGWGPPVRMAPWATRRAALLVADLLEEAATTALPLAADRGQHQTLHRL
                     RAVSQLYRLMRQEYDQPWMGLPFLDDRVVEACLAVRTHERGTPFAYKPLLARAMHGLMP
                     GHLLARATKGSTDTDFYAGLREQRAALNQLVERSRLAQAGLLDAAALGAALHTPVPRIS
                     ADLEDTLVVEHWLHHGRLTLPAATPSRSTVRSTRST"
     gene            complement(32445..32606)
                     /locus_tag="M878_RS96545"
                     /old_locus_tag="M878_21620"
     CDS             complement(32445..32606)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS96545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_21620"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_158692721.1"
                     /transl_table=11
                     /translation="MEIQKVLTNEERVAVEEPVAYEPPMVAEAGRFAHDTRGGYGKYRE
                     AGIGRFEA"
     misc_feature    complement(32770..32786)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    32806..32820
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            32985..33269
                     /locus_tag="M878_RS69945"
                     /old_locus_tag="M878_21625"
     CDS             32985..33269
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020552746.1"
                     /locus_tag="M878_RS69945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21625"
                     /product="DUF5132 domain-containing protein"
                     /protein_id="WP_023548533.1"
                     /transl_table=11
                     /translation="MPPVVPPFLLGLVFAPLAKRLVKPLVRGTVKTSMSLVMELKKAAH
                     EAGEELHDMTAEVAAELIGAELREEETAVGKPVKPRSPAGSGTAAGKAR"
     gene            33290..33622
                     /locus_tag="M878_RS000000100035"
                     /old_locus_tag="M878_21630"
     CDS             33290..33622
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS000000100035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_21630"
                     /product="hypothetical protein"
                     /protein_id="WP_023548535.1"
                     /transl_table=11
                     /translation="MTIQHPGDDGMVRFFSTAPPSPFVLPQTRKCVTEYGDVLADITTT
                     TDIMEESDSATNVLYRAELVLNNGSYTLVVRDLVHGTLRMTGVPRRMVAKFPAYLSMLN
                     LQHVDE"
     gene            complement(33604..34590)
                     /locus_tag="M878_RS69955"
                     /old_locus_tag="M878_21635"
     CDS             complement(33604..34590)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS69955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_21635"
                     /product="hypothetical protein"
                     /protein_id="WP_023548537.1"
                     /transl_table=11
                     /translation="MTATKSAKARRPLVSRGARGAAERAWERPLSADPPMAWERTAVTL
                     RHQLKAGAVTLHCVHTLRLLGCPHDALDYYWPPLLNLEALVYVGDLAVEREQADGPPAG
                     TAWRDGIEEVLRGYGCDTAEALADLRALEEYARWETETMSRRAQYSVDDLVRACHGRSS
                     DVRIMTGFGRRLAGLPGDESFDRLAGHMHAMGELISDVVGYAKDVADDSCNFYRMCVWA
                     VGVEAARARLHEVWRRLCDDLLCDLAAADRRSLVRFAQVFLLRPRPLRALAVKRSPTRV
                     YTLLPRPVLLTWIRWRLERGERLRLPAVPDPVPEPAAEGSSVHSSTC"
     gene            35037..37202
                     /locus_tag="M878_RS69960"
                     /old_locus_tag="M878_21645"
     CDS             35037..37202
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014896.4"
                     /locus_tag="M878_RS69960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21645"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_158692722.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 7.6e-46, bitscore:
                     155.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPETTSVHPPAARENLVETVHGRPVADPYRWLEDLTSDASRAWA
                     EAQDTLFAAHRTAWPDRDAWDERLKALSVTRRVSAPVWRGGRHFTERHLPGRDQAVLYA
                     TGADGTERFVVDAGTLAPQGRVRLAGWRPSWEGDLVACQFAVDGADITRLVVYAADGGG
                     AVDEPVEGLRHSPVAWLPGGQAFYYVGPAAEGPDGMLRVKLHRLGRPAGEDEEVFGEQA
                     DGFAYFGLTITPDGDRLVVSVARGIAHHNDLWLAETPVNDPARPTWQRLVDGTETKALA
                     SIRLHRDGGGRLHTDRGAPRGRILVTDRTAARGDGWRELVPQDPDAALDDSVLLDGLAL
                     AEPLLLVCWSRAATSRITVHRAADGKRIGEVPLPGSGTVRALRGRPEGGHEAWFTYTDF
                     GKPPAVFVFDAVSGRVAPWPGRGAPPGPRASVEPTGAPGSTAELLTSQVRYEADDGTPI
                     LLFLLSRADQPLNPPAGPPRPALLTAYGGFGVPMRPAHTPSARAWAQAGGVYAVACVRG
                     GGEHGNAWHAAGRGAAKSRAVDDLNDAARYLIDRGITAPDRLAATGQSNGGLLVTAALT
                     RRPDLYAAVAAIGPLCDMARYERFGIGHTWTAEYGTAVDPGQLDALLAYSPYHQVRPGS
                     RYPAVLLCGADTDQRTGAQHVRKMCAALQHATASPAPVLMRRTTTGGHAHASAGTAHDL
                     TADVTAFLAHHTGLPAPTSATADGSPR"
     gene            37276..39687
                     /locus_tag="M878_RS69965"
                     /old_locus_tag="M878_21650"
     CDS             37276..39687
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018099846.1"
                     /locus_tag="M878_RS69965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21650"
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="WP_023548542.1"
                     /transl_table=11
                     /translation="MSRYVTPPAEPHGHQHPVRGPLRLRSAVPGRQRWEAPVLAGRPRL
                     AGLLTAVLGKSPGVTGVRASAVTGSVLVHHDPALGAADIGAQLRAVLDDLLRQVGTQSQ
                     VPQPSAEPVRTREQAGDPAGAHQATRSGVRPRMLVAGGAAASLALGGSGLLLGPWVALG
                     AVGAATTLLIRRAWHETSDPRKLPASPLKPAEAARPVGNAGAPPLLRLARRHRRRIGRA
                     AGLSAAAELAELGVFTSLGALPLLLARGSSPVLTALGVTGTLPQLGVLTAVAALAKLIQ
                     AALSYRADLAWRTLGQDVEHELRSEVYPHVQRLPLRDLEGERTTRIAGVLSADIPHVGA
                     FLAHGPGELVQLATCFLVMAPAFLLLAPRLAWAAFLPVPVITWLSLRHHSRSGRAYAAV
                     GDRRVRLNSQVINTLEGSATVKSFCTEAEEAARVERLSDACRNDTRLNDRETARHIQTV
                     GTCASLSLLGTGLLAARDVFRGTLSLSSFNTLLALPSPVLYRLTRIGTTLEQYQHTLAA
                     LDRVEHLRNLPTEPDEGGRPLDPGRVEGELVLDGVTFAYPGRPPVLRDTRLRFVSGRTT
                     AIVGATGAGKTTIAKLLMRFQDPVAGRILLDGQDIRELRLQDLRRCIGFVAQDAFLFDG
                     TIAENIAYGTPHAEHAAIVGAAGIAQASGFIEALPQGYDTVVGERGAALSGGQRQRIAL
                     ARTILKDPPVVILDEATSAVDNDTEAAIQHALRNFTAGRTTVVIAHRLSTIRHADWIHV
                     MNENGTMVEEGAHQDLLTQDGQYASLWRLQTGMPERDPEDAGRVLVTATH"
     tRNA            complement(40204..40276)
                     /anticodon=(pos:complement(4716541..4716543),aa:Ala,
                     seq:tgc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="M878_RS69970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="M878_21660"
                     /product="tRNA-Ala"
     gene            complement(40204..40276)
                     /locus_tag="M878_RS69970"
                     /old_locus_tag="M878_21660"
     misc_feature    40382..40395
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            40459..41007
                     /locus_tag="M878_RS69975"
                     /old_locus_tag="M878_21665"
     CDS             40459..41007
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569181.1"
                     /locus_tag="M878_RS69975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_21665"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_023548546.1"
                     /transl_table=11
                     /translation="MDAAQQEATARARELQRNWYGEPLGALFRKLIEDLGLNQARLAAV
                     LGLSAPMLSQLMSGQRAKIGNPAVVQRVQLLQELAAQVADGSVSAAEATGRMEEIKKSQ
                     GGSVLSNTTQTTSGSGAPTVKRVVREIQSLLRSVAAAGDIIDAADSLAPTHPELAEFLR
                     VYGAGRTSDAVAHYQSHQN"
     misc_feature    complement(41314..41328)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(41586..41597)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 gagggggcgc tggagttcgt ccgctcccgg cacggcttcg gcgacggcag cgacctgggc
       61 cgtacgacga cccagcacat cttcctcagc gcgatgatcc gcaagttcaa gagcgcgggc
      121 acgctcaccg accccaccgc cgtctacggc ctggcggacg cggcgaccaa ggcgctgacc
      181 gtggacgacg gcctggacag cgtgaacaag ctgatctcgc tcgcatcgga catgaacaag
      241 gtgccgacca aacggatgac gttcacgacg atgcagacgg cctcggaccc gaacaacaag
      301 gaccgggtcg tggtgggccc gggcgccagg accctgttcg ccaccatcgc gggcgaccag
      361 tcactgacca ccggctccgg tcagaaggcc gcggccgcct cggcgaccgc gaaacccgcc
      421 gccggcgccg ccccgccggt accggccgca cagatcgccg tcacggtcga gaacggcacc
      481 gcggtcaccg gccgcgcctc cgacatcgcc gccgcgctga ccggccaggg cttcagcacg
      541 gccaccacca cggccaacgc gcccagcccc gcgacgagaa ccaccctcac ctacggcacc
      601 ggccaaaagg cccaggcaca gacggccgcc aaggcactgg gcctgtcccc cgcgcacctg
      661 gaacagggca ccggcaccgg cctgaccctg gtcatcggca gcgactggcc cagcggcacc
      721 agcttccccg gcgccacctc ccaacccgcg cccgccgaca ccaagaccgc cgtcggaggc
      781 gcccacgcct ccaccgccga ccaggccaag acctgcgcca aggtcagccc ctacaagaca
      841 gtcaacctcg acggcgtccc catgaccccc tcccaggcct acacggcagc acgcggcaaa
      901 cccgactccg acacctgann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngactccttc
     1501 acggttgtac agttgcgcaa aatagcaata aaggcagaag agaaggggcg ggcgggatgc
     1561 tccgcaacgg actggaaccc tggcacctgc tgatcgtggc gatcgtcatc atcgcgctgt
     1621 tcggctcgaa gaagctgccc gaagccgccc gcgggctggg caagtccctg cgcatcctca
     1681 agagcgagac caaggccatg agggaggaca gcgtcataca accctccgcc gccccgaccg
     1741 gggacgcgcc caccgatccc gcacccaccg atcccgcgct gcgggtcatc caggcgcccc
     1801 ccggagagac cggaacggcc cgcccggcaa cggagaatca cgcagcaggc tgacgctgga
     1861 cgccgcgctc tcctcaggga ctggcgacgt cgtagccgta ccgcagcggc tcagcggtca
     1921 cgccgtagtc gcggcggtag acgtacacgc cttccgcgcg cacgccgggc ggcgccgcat
     1981 cgacaggcat cagtctccgc atcccttgat cacccgatcc atgctgcgcc gcatggccgc
     2041 atgaactccg gtccggggtt atccgctgcc attgttgagt gttcaccaca ttcaggcacg
     2101 gaccggttgc ttttctacgc gctatcgttc agcagaacac cgccgatacg ccgtccatgg
     2161 gggagcagaa gttgcggcat ggctaccgcg aggaaaacca ggaggacggt gcagtcgagc
     2221 gcctggacgt ggcgaggccg ggcgatgtgc aggtactcga tgtgagttca cgcttccaag
     2281 ccggggctca agccgccgag ttgggcctgc tgcccccgtc gccgtcaccg ctgccccgcg
     2341 ccggacaccg gccgcgtccg ggcgaagtgg aggcatggct gctccatgtt cccgcgaacg
     2401 gcgccgccgc catggcgggt gccggctgtc tcgacgaagg ggagcggctc cgcgctgccg
     2461 cgatcaccgc cgggcggcca cggctccggt acgtcacggc ccacgtcggg ttgcgcgtac
     2521 tgctgggttc ctatctgggg ctggcacccg accaggtcgg cttcgtccgc gaaccgtgtc
     2581 cgatgtgcaa cggcccgcac ggccgcccgg ccctggccgg cgaatcgtcg ttgcacttct
     2641 ccatgtcgca ctcgggcgac gcggtgctct tcgcggtcgc gtcgtccgcc gtcggcgcgg
     2701 atgtcgaggc cccttcggcg agacacggga ggttcgacct gtcctcgtat ctgcaccctg
     2761 ccgagcagcg ggctctgcag gcgctggacc ccgcggagcg cactgcggct ctactggggt
     2821 gctgggtccg caaggaggct tatctcaagg gcgtcggctc gggaatcgcc ggtggtgtcg
     2881 gggcggacta cgtggggctg gaggccgcgt acacgaccgg cgcggccgac gcggaggagc
     2941 cgctcctgcc gatcggctgg acgatcctgg acgtcgccgt accggagggg ttcaaggccg
     3001 ccgtcgccct tcgggacggc cgtcccccgg gccggagacg aacctgcctg ccgacgcgct
     3061 ccttcggcct gacccaggcc ggccaccgcc ggtcacccga gggtgggcag cagccggtcc
     3121 cggaccgtcc gctggaagtc gcccccgtcg gcgccgggag gaaccagttc cgggtcgatg
     3181 caccggagcc ggaggacacc gaggtggacg gcgtggagcg agagcgccgt tgattcggcc
     3241 tcgggcaggt gcagtccggc ctcggtgagc aggtgccgca ggatgtccgg acggcgccgg
     3301 tgcgtctccg cgaggacctc gcggacctcg gggcggaccg cgtcggcctg caacgcgatc
     3361 ccgatgcccc ggaaggggct gtcgaagacg tactccagca gcgcggtcat cttggcggcg
     3421 ggatccggca gttcggccgg cgaggcggcc acctggtcgg tcgtcgcgca gcgccagtgc
     3481 tgcagcgcgg ccctgatcag cgcgtcgcgg ttggcgaaga accagtagaa gcttcccttg
     3541 ctggacccgt gttcggcggc gagggaacgg gcccaggtca ggaccggcgg gcaggccacc
     3601 ggcagcacgc tcacgcactc accgggactt ttctaccact ctggcccaga aattgacagg
     3661 gacttgacga ttgcctacgg tccgatcgtc aggttctacc gatcgcgccc gaaggtattc
     3721 atgaccgcgt ccccgacgtt accgaagtcc aggcagcagt tgatccttgc cgttctcaac
     3781 caatccgctt acgagcgccg atgacgcggg cagccactga caccatggga atcgggcaaa
     3841 aacttcctgg tggccgactt gacagtcaag ccacatatct ccccgaccgt cacatgtttg
     3901 ccttgtggac ctggtccggc cgcgccgtgg gggctgctcc gccggtcggt gatgtcgaga
     3961 ccgttgcctt ggtcgtcccg acatcagacc ttggcgggtt cgaggtgtcc gacgtcgact
     4021 gcgcgctgat cgagccggac aggctcgccg gcgcgcccct cgactcgccc ggccgttcgg
     4081 tggatgtctg gcgggcgcgg attgcgggcg gcgacccggc cctgccgatc gcagcgcatg
     4141 ccgttcccga tgccaccggt gtcgccgtga cgtcggcgga gcatgccgtg gccgtcttcc
     4201 atcacaccca tgctgttgcg accgaactgc gcacagcgct gaccgccgag ctgcggccgt
     4261 atcaggttcg cggtgtgagc tggctgcgcg agaccgtcga cgcacacggc ggcgcggtgc
     4321 ttgccgacga aatggggctc ggtaagacgc tgcagaccat cggctatatc gccgggcgcg
     4381 ccaaggaggg gccgcagctg gtggtgtgtc ccacgtcgct ggtcgggaac tgggcacacg
     4441 aaatcgcgcg gttcgcacct gacctgcgga cgacaatctg gcgtggcggg ccactcaaag
     4501 aggcggacag cgggacggtg gtgctcaccg gctacccgac gctacgcata cacagccctg
     4561 ccatgacgga gcatcagtgg atcactgcgg ttttcgatga ggcgcaggta ctgaagaacc
     4621 cccgcacgca ggtatcgaag gccgcgcgag ccattgcggc cgacgcgcga atcgccttga
     4681 ccggaacgcc cgtcgagaat cacctcgagg agctttgggc gctgctcaat ctggtcgcac
     4741 cgcaactgtt cgggcacaag acgcagttcc gccgtcgctt tgtccggccg atcgcgaacg
     4801 gctccctcgc cgccgctgcc cgactgcgcg gggcaatcga gccggtcgtg ttgatgcgga
     4861 agaagtccca ggtcgcaagc tcgctcccac ccaagatcca cgccgacttg atctgcgacc
     4921 tcaccgagga acagcagcag gtgtacgacc gactgctgga gcaggcgatc gacgacggct
     4981 tcggcagcgg cgcacggcgc cagaccaagg tgttggcggc cctgaccgcg ctcaaacagg
     5041 tctgcaatca cccgggcctg atcaccggtg atctcgatga gctgtcagga aggtcgggaa
     5101 agctcgacct gtgcaccgac attgtggcca acaacctcga aatcggatcg ccaaccctca
     5161 ttttcaccca gtaccggcag accggtgagc tgctggtgcg acactgcggc gaacagttcg
     5221 gtgtgggtgt gccgttcttc cacggcggct tgaatcagaa gcaacgggcc gacatcgtcc
     5281 gccggttcca ggccgacaac ggcccgaaag tcctggtgct cagtctgaaa gccgggggca
     5341 ccggactcac tctcacccgc gcagccgacg tcattcactt cgaccgatgg tggaatccag
     5401 ccgtggaagc gcaggcctcc gatcgagtcc accggatcgg tcagacccgc accgtcaccg
     5461 tcaccaccct gaccacgggg accaccgtcg aggagcacat cgcggccatg cactcgcgca
     5521 aatccgcgct ctccgatatc gcggatatgt ctggtgtcgc cgaattggcc cgcttggatg
     5581 atgaccgcct cattgcgatc ctgcgccgga agcgagacag ctgacatatg agcggcaata
     5641 atttcggtca cacgttgtgg gggaaggact gggttcggtt cgccgagccg ttgcgtcaga
     5701 cccgtcccga tccgcagctg ccgcgcgcgc gcagaatcgc acgcgacggg aaagtgcagg
     5761 tcacgatcga cggccggatc gtgcgcgccg tcgtacagca cggccgcaac gccgcggtgg
     5821 ccaacatcga ggttgcgccg atgtcccggg aggcgatggc cgggatcgcc cgccagctgt
     5881 gcggcgttcg gctcgtcctc accgacgagc tgtatcgcgc gaccgccgac gcgggccacc
     5941 ggcctgcacc gaaactcgtc ggcgtcgact gctcatgctc agctgacact ccacgatgca
     6001 tccacgtgct ggccgtctac tacgaaatgg cacggaacat cgatgacgat cctcggattt
     6061 ctctcgatat ccagggcttc ttccgcgcct catcggacag cactgaagta tccaccgcag
     6121 taacaccaca gcggtggatc gcgctcaatg cccttaatcc ggccgactac ttcatggtgt
     6181 ccacgtagtc agggcggttg caaagtcccg gtgagtgcgt gagcgtgcag gccacggtgg
     6241 tatgacgtgg ccggctggag tgccacgaac gcaacgaagc tccggttgat gccggtgacc
     6301 gatcacgtca cctgcaccgc ccggagcttc gatgtgggca gctgccggca gtcgctcacc
     6361 ccgtcatcgg ttgctcttcc tgatgctcac gcggtgaacg atccgaccgg cgccctccgg
     6421 cagttcggta gcggagtgga acgcgatctt ggtcttccac atcacaaggt cgccctgggt
     6481 ccacttgtgg cgatagatgt tctcgggatt gcccaggaat tcctcaattg caccgaacca
     6541 gcgcttgttg tcgttcgcgt cgaactggtc gaccgcctcg gtgtagccgg atgacccgta
     6601 cgcgtaacgc tgtccggtcg gctcgtcgac cggcgtgagc ggatgcacgg cgggcggata
     6661 ttccttgtcg acggcggcgc ggaactccgg cagagacagc ccgacatgct cgggacgcat
     6721 ccggaaacga cggctgtgaa ggtgagtcgc ggtagcctgc ccggccttct cgcggaggtc
     6781 ggccggcagc gcttccagca cgttgatcgc gctggcgaac agggtgtcgc cgtgaccttc
     6841 gggcacctgg actccctgca ggagggtgta ttccggcggg tcggggaggt aggtcgagtc
     6901 ctggtgccag aagttgccca cgcgcgcgac gccgatgggc ttgccgtcct tgaccacgtt
     6961 ggacgagatc atcagctccg gatagtccgg gtggcggtac ctgctgatgt tgaacgggac
     7021 cggctgcccg atcttccggg cgaactcgat ctgctgctcg gggctcagcg gagtctggcg
     7081 gatgaccacc aggtgcgagg tctccagggc gtcgacgacg tccgagacgg tcgtcgcatc
     7141 ggtcagtgcc tctgcggtca gtccgcggta ctcggtaccg aacccgtcgg agatcgacga
     7201 cttggacacg gttgttgcgc ccatgagtgg ttcctttctt tcgtggcgac ggtcaggtcg
     7261 gtgaaggggg tggcgggacg gtgctcccga cggtgggggc aggcgtcatg gaccgcctcg
     7321 gagagcggca tgacggcgca ccgggcacgg atcgcgccgg ccgtgctcac cccgcggagt
     7381 ccggagcgac ggtggacacc agctgtgcga cgagcgtgcg cttgaggact tttccgctcg
     7441 gccccaacgg gagggtctcg gcgaactcga cgcggcgcgg gtacttgtac gaggcgaagc
     7501 gctgcctgcc ccattcgacg atcttgtcgc cgacctcggg tgtggcttcc tccggccggg
     7561 acggcacgac gaccgcccac acctcctccc ccagcacggg gtgggggacg ccgatgaccg
     7621 ccacctggga cacggccgga tgtccgacga gggcctcctc gatctcacgc gggtagacgt
     7681 tgtagccccc gcggaggatc aggtccttct tccggcccac caccgagagg tagccgtcct
     7741 cgtccagcct gccgagatct ccgctgcgga accagccgtc gacgatgacc tcggcggtga
     7801 tgtccggccg gccgaggtag cccgccatca cgttgtcgcc gcgcaccacg atctcgcccg
     7861 tctcgcccac cggcaggagt tcgatgccgg cggtgttcgg ccgggctatc cccacggtga
     7921 cgttgtcgag gggaacaccg accgtcccgg ggcggcagac gattccgggg tggttgtagg
     7981 agacgctggt cgaggtctcg gtcagcccgt agccctcgta cacggggcag gcgaagacgc
     8041 gctgcacatc gtggaacgtc ttgaccggca gcgccgatcc gccgctgtag agccggtcga
     8101 tccggggaac cgccccgccc ttgtccaccg cgtcgagcaa cccgaagtac atcgtgggca
     8161 cacccatgaa caccgtgcac cggtgctctt gcatcagctt gagggcctcg gcgccggaga
     8221 accgaggcat catcaccatg gtgatcccgg cgtggaagcc ggtcagcatg gagcagatct
     8281 gcccgaagct gtgcggcagc ggcagccccc cgagcagtac gtcgtcgctg cggaacgcga
     8341 acggggtggc ggccatggtg tggacgttgt gcaggatgtt gcggtgggtg agcgtcacgc
     8401 ctttcggctt gccggtcgtg ccggacgtgt agaagacgac agctgcgtcg tccggctcgc
     8461 gcgcgacgaa gtcgtcgagc ggcgccgtgt gccgtgccgc ctcctccagg tcgacggcgc
     8521 cctcctgggg cgtgccgacc gtcagcagca gggtgcccag cggctgggcg gcctctcgcg
     8581 ccgggccgat caacgaatcc gcgcacacca ggaaacgcat gtcggcgtca gtgagtacgt
     8641 gcgtgatctc cgctgccgtc gacctgacgt tcagcgggat cacgacggcg cccgccgcca
     8701 gcacgccgaa gtacacgaga gggaactgcg ggtcgtccac cacgagcatg gcgaccccgt
     8761 cgccgggccg gaccccgttc tcgcgcagga cgcgcgcgta gcggcgcgcc cgctcccaca
     8821 gccacgcgta gccgaagtgc tcggactcat ggatcagggc cgggtgagcg ggccgccgga
     8881 ccgccgtgtc cgccagcacg gccgcgaccg aaccggtcag cgcgctcttc ttctgcgccg
     8941 ccgctgtgtt cctgctcaac tcgtcttctc ccacggatgc cgaaggaatg cggccggcac
     9001 gggcacggtc atgcaccatg ccggtcgctc gccgtcgcga tgtccagctc tttccagatg
     9061 ccgcccagca cgtgggcgag gttctcgacg tccttcgggt cgtgcaccgg ggacggcgtg
     9121 atcctgagga gttcctcacc ggcaggcacg tcgggggagg cgatcgactg gacgtagatc
     9181 ccgtgccggt ccaacagcat ttcggacgcc cgtcggcagg cctcgctgtc ccccacgagg
     9241 gcggagacga tgtgcgagtc ggtcgacaga cacgggatgc cggcctcacc gagcagacgg
     9301 tgcagcagtc gcgcgttctc cgacagagcc gtccgctcag cctcggacgc cctcagatga
     9361 cggaccgact cgagcgcgcc ggccgcgatc gccggcggca gcgaggtggt gaagatgaac
     9421 gagcgcgaca aggtgcggac cgtgtcgatg agtgcggccg gtccggtgat gtatccgccc
     9481 atcacgccgt aacccttgcc cagggtgccc atcacaaccg tgaacttgtc cgcaaggcct
     9541 tcacgcgcgg caattccggc gccctggggg ccgtacatgc cgaccgcgtg gacttcgtcg
     9601 atgtacgtcg tggccccgta cctggacgca agctcggata tctcggccac cggcgcgatg
     9661 tcacccagca tcgaatggac gctttccatc gcgatcagct tcggacggtc agcgggcgcc
     9721 gccgccagga gctcttccag gtgagcaaca tcattgtggc ggtaaatgta cttctccgcc
     9781 ccactgtggc ggattccgtc gatgatcgac gcgtgattcc tcgcgtcgga gaacacgatg
     9841 gtgtccttgg gcgtccccgc caggacggtg agggcgccgt cgttcgccgt gtacccggaa
     9901 gcgaagatga gggcggcttc cttgccgtga aggtccgcca gctccgcttc cagaaggacg
     9961 tggaactggt tggttccgcc gatgttccgt gaaccaccgg aaccgacacc gtggttgtcg
    10021 atcgcggctt tcatcgcctc ggcaaccctg gggttctgtc ccataccgag atagtcgttg
    10081 ctgcaccaga cctggatctg cgaatccacc ccgtcctgcg atgcggtggc ctgcggaaac
    10141 attccgaagc ggcgcccgac ctgcatgtgc tcgatcctgc gcccggacga agccgctccg
    10201 gtggtcccct tgggatacga ctccagatgc aggttcattt cgttcgcctt tccaatctca
    10261 agatgaagaa ctgtgagagt cgaatcgcct ggatcaggca ccggattgcc gttccgatat
    10321 ttgactcctg aggaccgcga tccaccgacc gagtgccgct ccattcttgc ccgtatagcg
    10381 gggctcgaga cagcaccttc gaccgggtga agcggcgcat cgatcggcta cccgatcggg
    10441 gtagccgatc caggacgacg tgctgtgccg ggcgatcgcc ggaccggcca acaccgggat
    10501 actcaggttg aatcggcgct gtcagggcag tcgtgacgag tggtgattcc tgcggtacga
    10561 cgacctcatg cggtatgcgc aagggggcgg gctgacgccc gcggagcagg agaagcggga
    10621 ggccgtgcgg ctggaggcgg ccaagtggtt cgaggccggg gcgggcacgg cgcagatcgc
    10681 ggctgagctg cgggggacgg accggtcggt gcggcagtgg cgggcggtgt ggcgccggac
    10741 ctgtccccga gtggtggaca cctctgatcc cggccccgct gagtgcgggc cgagcgggcg
    10801 cggcgtcacc ggtcggcaac ttctggcacc aggactcctc ctccgccgcc gttcaccagc
    10861 tgcacggcgt caacatcccc tccaccagcg ggcacaacaa attcgtcggc gccatcgacg
    10921 tctgcgaccg gctgtcggag gagtggaagg ccaagccggc ggaccggatc ggcgtacaca
    10981 ccgtgggcaa acggctgcgg atccgcccgg agcaagtcgg cctgttgccc gccgagttca
    11041 aggtccagga cgagagacgg gtctacaccc acgtccggac ccacgaccta ccacgtcacg
    11101 accgaggtcg agccgggtgt cggcgtcaga ggttggactt cacccggttg tcctggacca
    11161 ccggctccgc gggctgccgg tccggacgca gggcgatcac cagcaggagc gcgccgcaga
    11221 gggcgatcag catggtcccg gcggcgctga tgtgcatggc cttgatgaac gcgtcgttgg
    11281 ctacgcgcac caggtcgggc tggtggatcg cggcggcggc gtgccgggcc tgctcggcgg
    11341 agatccgcgc ccgggcctgc acctgctcgg ggtacccact cagcgagctg tcgaccgcgt
    11401 gccggtaggc gagcgacatg atcgtgccgc ccaccgcgat ccccatcaga ctgcccgtct
    11461 ggcgcacggt gttgaggacg gccgatccgg caccggcccg ttccagcggc aggacgctca
    11521 tgagtccccc cgtcaccggg ccgatcacca tgccgatcga caggccctgg atcatgtagg
    11581 cgatctcgtt gaagaccagc ggggtgtgca gcccgaagag catgttgcag cccatggcca
    11641 gccccgccgt ggtcagcgcc gtcgcggtga ccacgcggag cgtccagcgg cgggccagcc
    11701 ggaccccgag cggcgccccc acgatcgccc cgagcgcggt cggggagaac gccagccccg
    11761 cctgcagcgg cgagaattcg cgtgcgccct gtaggtagaa ggcgccgtag aagctggcgg
    11821 cggtcatggc gaacatcagc agcccgagcg ccacgttggc gaggccgaac atgcgctggg
    11881 cgagcagccg ggggtcgaag ctgggctgcc ggtggcgcag ttcgacgagc acgaagccgg
    11941 tcagcaggac cactccggcg gcgatcgggc cccagaccga caccgggctc catgaggcca
    12001 cctgccccgc gcggatcagc ccgtaggcca ggaaggcgag cccgctgatc gacagcagca
    12061 gcccggccgg gtccagcgga cgcggggtgg gactgcggaa gttggggacc agcgtggcga
    12121 tcccgatcag cgacagcacc gcgatcggga tgttgaccag gaagatcgag ccccaccaga
    12181 agtggccgag gaggacgccg gccagcagcg ggcccgcggc gataccgacg ccggcggacg
    12241 tcgatgagat gccgatcgcg gtcgcccggg cgggaccgct gaaggtccac atgaggatgg
    12301 ccacctgcgc gggcatgatc agcgcgctcc ccatgcccat cgcggcccga gcggcgatca
    12361 gttggtccgc gtcgcccgcg tacgccgccc acaccgaggc gccggcgaag accgccatcc
    12421 cggtggcgag cacggtccgg tggccgaacc ggtcgcccag ggcgccggag gtgaacatca
    12481 aggtggcgaa gaccagggtg tacgagccgg tggcccactg cagctggctg gggctggcgc
    12541 ccaggccacg gaccgggtcg gcgagggtct cgaaggcggt ggtgaggatg gtgttgtcca
    12601 gccagatcag cagcgaggac aacaggagca cggcgaggat caactgctgc cgggacttcg
    12661 gcagcgttgg aggcgtcgtc atggagacct tcggtaggat cgacaagaac ctgacgattt
    12721 gattgtgtgg aatcgcccgg aacctgtcaa tccctgatga accgtcaccc gtccaccggg
    12781 acgcggcggc ttccgattcc cgccgccggt ccgaccaggg gtacccggac ggctaccccg
    12841 gtcgggtgac cgcttcgatg cgccggttca gccggtcgaa cgttcttttc cgcgcatccc
    12901 gtgaaccggc aggatcggat tgcacccggg ccagcagatc gcgatccacc ggggtatgta
    12961 tcgagaggca gggtcatgac cccacaggac caatggtggc gcgaaagcga cagctacgtt
    13021 tcggatattc tctcggtgtt cgcagcggcg ccggatcgcc ccgccatttt ctggcgcggc
    13081 cgagcgttct ccggcggtga gttgatccgg tccaccaccg agatattcca cgcgctgcgc
    13141 gaccgcggcg tgggggaaga agatgtcgta gcgattctgg tcgctcccaa cagccccgag
    13201 atgctcaccg cgcggtatgc cgcgcatctg ctcggcagca ccgtctgcta cctgcggtcc
    13261 accaatccgg gaaccagctc gacgatcctc ccgctggacc accagatcca gatcctgcgc
    13321 gacaccgctg cctcgacggt gtacgcggac gccgagaacg cgcagcgcgc acttgaactc
    13381 tccgaaggca tcggcggact tccggtgacc cgcgtcgacg gcaccggcca cgacgcggcg
    13441 agccgagccg acgccccgca ggccgcgccg tgggacccga gcaccgtggg ggtgatcggg
    13501 ttcaccagcg ggagcaccgg gcggccgaag ggcatccggc tctccggcca ggtctggaac
    13561 ggcggggtcc gcggcatggt ggcggccgat cgcgcggccg aggacgtgag gctgctggtg
    13621 acgacgccgc tgagccacac cgtcggcacc atggccgacg cggccctggc cctgggcgga
    13681 gaggtccacc tccacgagca cttcgatgcc gggcagttca ccaagacagt cgaagagtcg
    13741 gcgatctcgt ggaccttcat ggcgacggtc cagctgttcc agctgctcga ccacctggag
    13801 gagctcgggg cgcacgacct cgaatccgcc ggcctgtcct cgctgaagcg gctgatctac
    13861 agcggcagcg cggcggcacc cgccaggatc gcgcaggcgg tccgcatcct cggcctcatc
    13921 ctggtgcagg cctacggcac ctcggagtcc ggtcgtatca cgtcgctcaa gcgcgaggaa
    13981 cacctcgacc cgtggctgtc gaccaccgtc ggccgccctt tcggcgaggt cgaggtcgtc
    14041 gtcggcgacc tggtctcggg agctccggtg ccgaccgggg aggtgggcca ggtccgcgtc
    14101 cgctcaccgc acctgatgga cggatacacc ggcgacccgg aactgaccgc gcaggtcctc
    14161 cgggacggct ggtactacac cggcgacatc ggctactgcg acgagaaggg ctatctgcac
    14221 ctgctgggcc gggtggccga agtggtcaag gtcgacgggg tcaaggtcca cccactggtg
    14281 gtcgagcggg aaatcctctc cctgccggga atccggcatg ccgcggtcta cggcgtgcag
    14341 gaccgggacg gttccgagca cattcacgcc gcgctggtct gcgaccccgc ggcggaggtc
    14401 gagacggaga gcattcgcac acacattgcc gagtcgctat cggtgctgca cgcgccggag
    14461 aagatcacga ttctcagtgc gttgccgctg aacgacaacg gaaagcccga caagctgcgc
    14521 ctgcggctgc tcgaggcctg atccgggaaa ttcgacgccc ggaaccccca acttcgacag
    14581 agaagacgaa cggaatgaac ctgcatctgg aatcgtattc cgacggcccc atcgccgcgg
    14641 atgtcgccgc ccgccggcgc gagttcctgg agatcgcccg ccactccggc aagttcccca
    14701 ccgccaccgc gcggcaagac ggggcagacc tgcagatcag cgtctggtgc agcaacgact
    14761 acctcggcat gggcgagaac cccaagatca tcgaagcgat gacgagcgcg atccaggccc
    14821 acggcgtagg ttccggcggt tcccgcaaca tcggtggcac caaccagtac cacgtccagc
    14881 tggagcggga acttgcggag ctgcacgaca aggaggccgc cctcctcttc acctccggct
    14941 tcaccgccaa cgacggagcc ctcaccgtgc tggccgggct gccgaaggac accgtcgtgt
    15001 tctccgacgc cgagaaccac gcgtcgatca tcgacggcct gcggcacagc ggcgcgcaaa
    15061 agcacgtctt ccggcacaat gacgtcgctc acctggaaga gctgctcgcg gccactcccg
    15121 ccgaccgtcc gaagctgatc gtcctggagt cggtctactc gatgtccggc gacatcgcgc
    15181 cgctggccga gatagccgag gtcgcgaacc gctacaacgc cacgacatac ctcgacgagg
    15241 tgcacgcggt cggcatgtac ggccccgagg gcgccggcat cgccgcccgg gagggcatcg
    15301 ccgaccagtt caccgtcatc atgggcaccc tggccaaggg cttcggcacg gtcggcggct
    15361 acatcgccgg accggccgcc ctcatcgaag ccgtccgcac gctgtcgcgc gggttcatct
    15421 tcaccacctc gctgccgccg gcaatcgcgg ccgggtcgct gacctcggtc cgccacctgc
    15481 ggaactccga ggtcgagcgg caggcgctgg ccgagaatgc gcagctgctg caccgtctgc
    15541 tcgacgaggc ggacatcccg ttcatatccg cggactcaca catcgtgtgc gccttcatcg
    15601 gggacgaccg gacctgcaag caggcatcca gcctgctgtt caagcggcac gggatgtacg
    15661 tgcagcccat caacgccccc agcgtgccgg ccggtcagga gatcctgcgg atcgctccgt
    15721 ccgcggtgca cacgcgatcc gacgtcgaga acttcgccga ggcgctccgc gacgtctgga
    15781 aggagctgga catcccgtcg gcgagcgacc ggctgctggc tcagcagagc tgaaagagat
    15841 tctcattccc cggcctcgtg cgtccgaaac ctgtgacgga gcgcacgagg ccgtcgcaca
    15901 tccgcctccg atcggggttc ggcgcaccga tacaggcttc gcagacacct ggccgcggcg
    15961 ggcgagccga ccgggccggc aggttctttg gcacctacct gccaacggcc ggggagagtc
    16021 gtccggatgg ccatagcatc aatcacgaaa ggcaatccaa gggggcaaag acataatggg
    16081 cgagcgaggg tgcgcagttg tcaccggtgg ctcccgggga attggtcggg cggtcgctgt
    16141 ccagctggcg gcggacggat atgacatcgc gttctgctat cgctccggcg gtgacacggc
    16201 cgtgcaggcc gagaaagaaa tccgcgacct gggcgtggag tgctatcacg cgccctgcga
    16261 tgtgaccgac ctcgagtcgg tgcaggcgtt cctcaagacc accgaggaaa agctcggtga
    16321 catcgtcgcg ctggtcaatt cggccggcat cgtcaaggac aatccgatgg tcctgatgcc
    16381 gcccgcggac tggcacgcgg tcatcgacac caacctctcg ggaacctaca acttctgccg
    16441 cagcgtggtc ttcggattca tgaagcgcaa ggccggcacc atcgtgaaca tctcgtcggt
    16501 cgccggcgtg ttcggaaacc cgacccaagc caactactcg gcggcgaagt cgggtatcca
    16561 cggcatgagc aaggcgctcg ccaaggaagt cgccggatac ggcatccgtg tcaatgtggt
    16621 ggcgcccggc ttcatcgaga cggacatgac ctcagaactc cccgagaagg cccggaagac
    16681 cgcgctcggg atgatcccga tgaagcggat cggcgagccc aaggacgtct cagagctggt
    16741 gtcgttcctc gtctcggagc gtgccgccta catcaccggc caggtcatac aggtcgacgg
    16801 cggaatcgtc ttctgatgcc ggaagcacgc aggcgcgccg cgcccctgga cgcggtcgac
    16861 gacatcgttc aggtcagcga ttccgagatc acggcgacaa aatcggtgca cgccggggac
    16921 ccgtatctcg aagggcatta cccggacttc acgatctacc ccggcgtgtt catcatggaa
    16981 tcggtgaacc agacggtcga cgcatacgtg gcacgcacgt tcggcgccga tcggatcgcg
    17041 gatctgacca ccgtcacgtc cgcgcgcttc acctcaccgg tcctgcccgg ggacacgctg
    17101 caggtgtcct gcaagctcgt cgtccagggt gatgacctgg ccgtggacgc gaactgccgc
    17161 aacgccctcg gcgaggccgc ggcgaggctg aagctggtgt accgaatcac ggacgggggc
    17221 atccggtgat cgaccacgcc ggaattcgga acatcatccc gcaccgccac ccggtcctgc
    17281 tcgtcgatgc ggtcctggag ttgtctccat tcgaccgcat cgtcaccgta aaagcaattt
    17341 ccggcagtga gccgtgctat gcgaggatgg ccgaaggtct cggttcgagc gctttcgctt
    17401 atccgaagcc gctgctcatc gaatctttcg cccagagcgg tgccgtgctc tggttggaaa
    17461 gcatcaagag tcgtggcgag agcctgaacg gcacactgat attcgccgcg gcccgaaatg
    17521 tcgaattcca tcggccggtc tatccgggcg acaccgtacg gcacaccctg aagatcgacc
    17581 aactggtcgg caacaacgcg ttcctgtccg gccggagttt cgtcggcgac gagcccgtca
    17641 tgaccgtcgc cgaggccatc gcggtcgtac gccccaacga ggggatcgcc cgccgggcat
    17701 gacgccccat tggcggaaga cccatcgagt cgacacctgt tcgtcgactc ggctattcag
    17761 ctgcgcattc agcagcgaac agacaaccca ggaagtggtg acgagatgac gaccgcaatc
    17821 aaccagcagc tgatggacga actgcgcgag atgatcgcgg aggttctcga ggaggagccc
    17881 gagaacatca ccgagaccag cctcttcatc gaggagcacg aggccgactc gcttcgggcg
    17941 atcgagatcc tggcccgcat cgagaagaag tacaaggtct cgctgccgca ggagctgctc
    18001 gccgacatgg tgaatctgcg ggccgtgtac aacaccgtgg tcgagtactc cgacgggaac
    18061 ctctgacatg acccgccgag tggtgatcac cggcctcgga cctctgtcaa ccatcggtgt
    18121 cggtccggac gcattcgcag ccggcctgcg cgccggcgca agcaacagcg ggcccatccg
    18181 cagtttcgac gcctccggat tcccgcacaa catcgcgaac gaactgggcg acgttcaccc
    18241 ctcggattac gtcacgaaca tcgacccgga ggcctggggg ccggccagcc tcgccgcgnn
    18301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19021 nnnnnnnnnn nnctcgcggt cgacgacgcc ggcctcgacc gcgccgagct gcggcgcggc
    19081 cgggccgggt cggtcttcgg cacgaccgga ggcgagaccc gcctccatga ggacgcctac
    19141 gagaggtggc tggccgaggg gcctgccgcc gatttcagcg acctcgttcc gaagatcccc
    19201 gcctaccggc tcgccgtcgc ggccaaccgc gaactcggca tcgacggcga ggcggtgacg
    19261 ctcgccaccg cgtgctcggc gagcaactac gcgatcggct acgcctacga catgatcgcg
    19321 ggcggcgact ccgactacat gatcgccggt ggctcggagg ccatgtgcgc gttcgccgtg
    19381 gccggcttct accggctcgg cgctctcgcg aaggacgtgt gcacgccctt cgacgcgaac
    19441 cgcaagggca tcctcatcgg tgagggcagc tccgctctgc tgctcgagtc gctggactcg
    19501 gcgctcgccc gaggcgccag gatctacgcc gaagtgctcg gctacgggct caactgcgat
    19561 gccaaccaca tggtttcgcc gctggccacg tcgatcgccg agtgcacccg ccgggcccac
    19621 gagaacgccg gggtgaagaa ggacgagatc gactacgtct gcgcccacgg caccggtacg
    19681 ccgtcgaacg actccgccga ggtcgccgcc atgcgcgagg tcttcggcga ccagctcccg
    19741 ccgatgagct cgatcaagtc gatgctcggt cactccatgg gcgcggcaag cggtttcggc
    19801 gcgatcgcgt gctgcctggc gatccgggac ggtttcatcc cgccgaccat caacctcaac
    19861 acgctcgacc cgaacttcga ggggatcgac gtggtgccca acgtctcgcg ggacgccgac
    19921 gtgcggatcg tgcagaacaa cgggttcgcc ttcggcggca acaacgccat cacgatcttc
    19981 gggaggtacg agtgagcgcc atggccgtga ccggatgggg ggtgctctcc gccatcggca
    20041 ccggtgcaga ggagttctcc gaggcctggg gcgagcgccg cagcggccgc aaggacgtga
    20101 cggagatgtt cgagcagaag ctcccgtccg aaaccgcctg cgccatcccc gacttcgacg
    20161 tcaaggcaca cctgggccgg aaggggacca gcttcttcga ccgctcgacg gcgctgtccg
    20221 tggtcacctg caagctcgcc ctcgaggacg ccggcctggt ccgcgacgcg aaggacgagg
    20281 agaccgacgg cggcatcggg ctcgtgctcg ggctgagcag cggtgggccc caggcgatgt
    20341 cggacttcat ccacgagatg tacaccagtg agaagccgta cctcgtcaac ccgctgctgt
    20401 tcccgtacgc ggtgatgaac ggcgcggcga gcgccacggc gatctggcac aacctcaagg
    20461 gcgtcaacgc cacggtgtcc ggcgggcaga tggccttcct gaccgcgctg cggtacgccc
    20521 gcaacaaggt gcgcagcggc tatgtgaacg ccgcggtggc cggtgcggtc gaggagttct
    20581 ctccgacccg ggcctgggcg tcgcaccagg cccgcggtgc cggggaggag cgtgtcgacc
    20641 tcggcgaggg cggtgccttc ttcgtgctgg aggacgctca gaccgtgcgg acggccggcc
    20701 gcggcctcga cgcggagatc ctggcggtcg agtgcggtct ctacggagag cctggcagca
    20761 aggacgaccc ggccgtcggc atgacggagt gcatcatccg ggcgctcgaa gccgccggcg
    20821 tcgcggcgag cgacgtctgg gcggtcgcgc cgtcgctctc tggttcgccc aagcgcgacc
    20881 ggatcgaacg ggtggccatc accgcggcgc tgggcactga caccccgaac ctcctgccgg
    20941 tcaaggaact ggtcggagag acctactccg cggcaggcgg cctgcagttg gccgcgctgc
    21001 tcgcggagca ccgcaggaac cccgagcgcg acggcgcggt ctccctggtc acgtcgctca
    21061 cctccgaggg gatggtcggc gtggccgtgg tccgagggtg gagccgtgcg acgagcgcat
    21121 agcgcctggg aaccggtcgc ccggtcggtg gtcgacggcg tgtcactgac agcgcacagc
    21181 ccggcccatc gtccgacgat ggtcatgctg cacggcctgg aggacgactg gcagagctgg
    21241 aagccgatgg cggacaggct gggcgaccgg ttccactgct atgcgatcga cctgccgtgg
    21301 cgggccggcg gcggctacga gtggcgcgcg ggcgggacgg ccgcgcaatg ggtggagaac
    21361 gccctggcgc tgatccccca gccgatctcg gtactcgtcg cccattccat gggcgcgaac
    21421 gccgtgctgc actggctcgc gtcgggcacg ccgcggcggg tcgacgctct ggtgctgctg
    21481 tccccgttct accgcctggc ctccgccccg gtggactggg cgatgttcga ccgctcgctc
    21541 gccgacttcc ggaccgtcat ggcggccggg ctgcgagcgc gtctcggtga gcgcgccgag
    21601 cggctcgaac cggagatcgt cagcctgatg gccgagaagg ccctcgaccg catcggtccg
    21661 gagggctttc tcagcctgtt cgacatcttc atctcctcgt ccgggatcga cctctcgtcg
    21721 aacaccgtgc cgacactcgt cgtcggcggc tcggccgatc ccggcatcag cggtccacgc
    21781 gccgaggccc tgggccgcga catgccgacc gcggagatcc ggctcgagga cgagctgacc
    21841 cacttctgtc acatcgagca gccccaacgg gtgtccgaac tcgtctcgga gttcctgctc
    21901 cgccgcctgc ccgccgccct ggagggcggg cggcggccgg cactggaagg agtgcacctg
    21961 tgagcaaccg ctaccccccg aagttctact tctccctgca cagcccctac agctggatgg
    22021 cgagcaggct gctggccgag cgctgcccgg atgcgctcga gtcgatgcag tggattccgt
    22081 atttctaccc ggacgagcag acctggaagt cgatggcgga aagggggatc gagctgcact
    22141 acgcggacat gagcaaggcc aagcacctct acatcctcca ggacgtcaag cggctgtccg
    22201 cgcggttcgg cttcgacatg gcctggccgg tcgaccgcga gccgtggtgg gtgctgccac
    22261 accacgcgtg gctcgccgcc aagcggaccg gcgaccagaa cgctctgtac tgggcgctgg
    22321 tcgaggcccg ttggggtcgc ggtgagaaca tctgcgaccg ggagacggtg cgcaagatcg
    22381 ccgacgcggc cgggctcgac ggcgaggcgc tgagcgccgc acccgaggac ccggagctgc
    22441 gcgaagaggg catggccgcg caggaggcgg cctacctgga cgacgtgttc ggcgcgccgt
    22501 acttcaagat cggcccccag cggtactggg gcctggaccg cctcgacgac ttcatcgcgg
    22561 gattccggca gtggcagcag aagggcaagg cggcatgacg acgcagccga acgccgaccg
    22621 gacaccggag gcggagagcc tgacaggcct gcgtcgcccg gtaccggtcg tcctcgacat
    22681 cgacgacgat ccgatggagg gcattccggc cgaactggtc gacatggtgg gccagttcga
    22741 ccgggacacc gcgggcggct gcggctgatg gcgtccgtac ccgcacagac acactggatc
    22801 gacggcgcct ggaccaccgg gcacacccgg tggatcgacg tggtcgaccc gacgaccgag
    22861 gagcgcctgg cggccgtgcc ggcgggcacc acggcggacg cggaactcgc ggtcgcggcg
    22921 gccgcgaagg ccttcggcca ctggtccgcc gtcccgctcg aggaccgcgt ggccgcagta
    22981 cgggcggtcg cgaaggggct gtcggcccgg cacgacgaaa tcgccgcgac gatcaccgcg
    23041 gaggtcggtg tgccgacgtg gttctcgcaa cgggtacagg cgagcctgcc ggccgccacc
    23101 tcggctgcgg tcgccggcat cgcggaggag ttcgcctgga ccgagcagat cgggcactcc
    23161 accgtgatcc gcgagccggt cggggtggtc gcggcgatca ccccgtggaa cttcccgctg
    23221 caccaggccg tcgccaaggt cgtaccggcg ctactggccg ggaacacggt ggtgctgaag
    23281 ccgagcgaga tcgccccgct gaccgcgcgg ttcctcgccg aggtcacccg cgaggctcag
    23341 atccccgacg gcgtcctcaa catcgtccac ggcgagggcc cggtggtcgg cgaggcgctc
    23401 gccacccacc ccggcgtcga catggtgtcc ttcaccggat cgacggcggc aggcaagcgg
    23461 gtcgcggcac tcgccgcggg gaccgtcaag cgggtcgccc tggaactggg cggcaagtcc
    23521 gccaacctgg tgcttccgga cgccgatctc ctcgccgccg tccgggccgg cgtcgcgaac
    23581 tgcttcatga acagcggcca gatgtgctgg gcctggtccc gcatgctggt gcccgccgcg
    23641 ctgcacagcc aggcggtgga ggcggcggcc gcggaagcgg cggccttcac cgtcggcgat
    23701 cccgtccagc cggacacccg cctgggcccg ctggcgtccg ccgcccagcg cgaccgcgtg
    23761 cggggctaca tcgagcgcgg agtcgccgac ggcgcacagc tcgcggccgg cggcccgaca
    23821 ccgccggacg ggctcgaccg cggctacttc gtccgaccga ccgtcttcgg cggggtcgat
    23881 ccgaccgcgg tgatcgccca ggaggagatc ttcgggccgg tgctgtcgat catcccgtac
    23941 tcctccgagg acgaggcggt ggagatcgcg aacgccaccc ggtacggcct cggcggcgca
    24001 gtgttctccg cggaccccga ccatgcgctg gccgtcgcca ggcaacttcg caccggacag
    24061 gtcgacatca acggcgcggc cttcaacgcg gttgccccgt tcggcggcta ccgccagtcg
    24121 gggaacggcc gcgagctcgg ccgcttcggg ctggaggaat tctgcgaggt caagtcaatc
    24181 caacgatcgg catccgtgtg acggtcgctg cagggaagtg aggcaccgtg ccgacccgca
    24241 cgctcgacga cggcatcgag atcatcctga tgatccgcga cgacatgcgg cgctacgggg
    24301 tcgagggaat gttccgttcg ctcgacactc cgctgacgac gcatgcctgc acggacttcg
    24361 gtgagctcgc cagattctcc aacggccagc tgatcgtctc ctccgacgat gtcgcgggtc
    24421 ccatctccga cgagaccgcc ggcaccctgc gcgcgcacgg catccgtatg ctcatcctgg
    24481 tcgactcggc cgccgcgctc gaccagtcgt gggccgattg cgctcatggc ttcctcgact
    24541 gggcggacct ccgcccggag tcactgcgcg acgcgatcgc cgacgtcgcg tccgggcggt
    24601 tccacatgtc ggagtccctg gcacggcggt cggtgacggc acccgagcag gccgagagcg
    24661 acccgaccgc gcggcggtcc tcgatctcgc tgacggcacg tgaactccag gtgctgcggc
    24721 tgatcgccgg cgggctgagc aaccggcagg tcgcgcgctc gctgagcatc tccgagcacg
    24781 gcgtcaaacg cctggtcgga atcgtcctgg ccaagctcaa ctgcccgaac cgcaccctcg
    24841 ccgtggtccg agccatcgag ttggggctcc tcaccctctg aatcggccgt tgcccggaag
    24901 gagcatcgac tcatgtcaca ggtccaccgc ggccgccaca ccgcacacat cgagggcgac
    24961 ttcgtcgtct tcctgatcgg catgcatgtg aaccgcccct ggcggatcca caagtggtgg
    25021 ccggtcttcc gctcgatgtt cggcatgatc aaggatctgc gcgagcatcc cgagaagggc
    25081 gccctgtgca gttacttcgc gctgatctcc ggcgtcgggc cggcggtcgt gcagtactgg
    25141 cgcagcttcg agcatctcga ggccttcgcc cggaacaccg acgacccgca tctgccgtcc
    25201 tggcggcggt acaaccagcg ggtcctcaag tccggggacg tcggcatctg gcacgagacg
    25261 tacctggtga aggacgggca gtacgagacc gtctacgcga acatgggacg catcgggctc
    25321 gcccgggccg gcgagctgaa gcccgtacag gccaagggcc acacggccgg gcgccggctc
    25381 ggccgcaccg ccgaggacga cttccccgac ggcacccgcc cagggggcgg ttcgccgtcg
    25441 tagtgcccgc aagtgccatg gccggggacc accacgcggc ccccggccgt cgtatcgggc
    25501 cgacggcctc actccttggg cgtggcccct cggtttgcgc ttggcccctc ggtcttctca
    25561 gtcttcccgg tcgtcgacgg ccggtccgat ggaaaggtga tgcacgatga acgctgccac
    25621 gacgagcgag gcgctgctgc cgcccatcga caggtcgtgg cggacctggg ccggcgctct
    25681 cggcggcctg gtgtccacgc tgatgcttcg gcatgcaggt gaccagctga ccgtggacct
    25741 ggcgcccagg gcgctgcaca gctcgttcct cgccccggtg tcggaccacc cgctgctggt
    25801 gcggtcggag gtggtgcgcc agtcgcggac cagcgccgtg gtgcgctcga cgctcgagca
    25861 gcacgaacgg ccggtggcac tggcgacggc actgttcggc accatcgggg acaagccgac
    25921 gctgcaggcg gctgaggcac cggttgtgcc gtcgcccgag gactgcccgg atgccgggtt
    25981 cccggcccgg atgttcccgt acgccgccca cttcgagacc aggatggcgg gcgaggagcg
    26041 gccgttcggc ggggggacgc accccgagat gaccgcctgg ctgcggttgc gggagcccga
    26101 cctgccgatt gccgcggcgg cgctggtcct gctcgacgcg atgcctccag cggtatacgc
    26161 ggcggcctcc gagctggtcg cggtaccgac cgccgagtac tcggtgcact tcaccgacgg
    26221 actgtcgttc gccgagagcg gcgactgggc gctggtccgg gtcgggacgg atcagtcgag
    26281 tgacagatgg acagtagagt ccagcagcct gtggaacgcg gacggcaccc tgctcgcggt
    26341 cggccggcag acccgtcagt tcctgcgtcc gacagcgccc ggcagcgccc tcaaggttcc
    26401 gcccacctgg tggcagcgcg cctgaccccg ctcacccgca atcgtccggg attcctcccg
    26461 aaaaagagca caaaataaac acaaagaaag aaatacctgc ctcccgcccc cggtcgaccg
    26521 aggacaggag gcaggggtca ggccgagtac cggtacggca attcctcgtc gcgaccgcca
    26581 cgcctcagca gaccgtcccg cagtgcgtgc acgccggctt ggaagcggga attcgcatcg
    26641 agtcggctca tgagctcggc cacccgccgc cgataggtgc ggagcgatat tcccagccgc
    26701 cgggcggcaa cctcgtcctt ggacccgcca gccagttcat tgacgatctg cagatccgcc
    26761 tcgtcgaact cggaccgggg gtagcgcaaa tagctcaccg gctcgctggc gccattccag
    26821 acggccgtga gcaatgactg cagattcttg atcaccggcg gcgcccagat cgccaggcac
    26881 tgctcctggg agaggctcac ctgggtacgc atgaaggcga cctgggagtc cacgatcacg
    26941 agttcctgca gcttggtgtc ggtgacccgg acccggatgc cgcactccgc ggcggacagc
    27001 aggtagtccg gagtgcacca gctggggagg tcgtcgcaac gatagagctc tcgcacggcg
    27061 accctccgcc gtgccgcgtc accaactatt ttctgaaccg tccggcgccg ttcgctggag
    27121 taccattccg atttcagtgc cgatatcatc acgtcgtagc gggcccgcat gacggactgc
    27181 agcgcggata tccgcatctc gtccgcattg tcgaattgct cgatgagcct gccctgctca
    27241 actcccgaaa gtatttccgc acgagtcacc tgatgcgtgc ctgaaggcgc cagcaagaat
    27301 tcccccatgg gcttgacccc tgaactttct ccttcaaact ataccggccg agaactccac
    27361 tcaagcgtga cctacaccaa attcgtgcat atactcgggg tcggcagggg ttcagcggcg
    27421 ggccgcggag atgccttcaa gccactcacg gatcgcggct cgctgctccg gcgtgaacgc
    27481 ggcttccaat tcggcttcgc agcggtcgac ggccttgcgg gcagcggcca gacgtgtccg
    27541 cccggactcg gtgacgaaga tctgatggct gcgccggtcg gacggattcg tccgccgctc
    27601 gatcagcccc tcctgctcga gcccgacaag catctcgttg gcggcctgcc gggagctcgc
    27661 cacctcccgg gcgatgtccg acgccgacat cccgggccgc acctcggcca tcagcagggt
    27721 ggcgtactgc gaggtcgaca gcccgaacgc cgtgagctcc ccggcgatcg ccgacctcat
    27781 gttcagccag accctgcgga ccaggaaggt cagcgagccg actgcggccc tgcggggatc
    27841 caacgctccg cctcctcggc tagtggcagg ttcttgacga tgacccgaga ccaccgggct
    27901 tgtcaagttc ttgtcgaaca gagcaaagcc cacccgccac ccaggggccc tggcctcgat
    27961 ccctgaccgg tgacgaagcc cgagccgggc gatcggccgg tcgggggtgc tggtggcgag
    28021 gcaggtgatc cccaggccgt ccgcgtcggc gatcctcaac tgcacgccgg gatgaggtcg
    28081 ttccttgcga acaccaaggt ccgcttcggc aatccctacc ggaagggagc actcgggctc
    28141 gcggcattcg gcgcggtgag aaccaaagac acctgcctgc aagcccgtta caagcggatc
    28201 accacccgcc gcggcccgct cagggccctg gtcgccgtcg agctcgatca ccaccgcgat
    28261 ctggcacatg ctcagcgaca acgtcaccta ccgcgagctc ggcgcctact tcacccagcg
    28321 caacccccaa cgcgccaccc gccgcgcgat caacgccctc aaccagcacg gctacaccgt
    28381 cacccgcaac ccgcggggag ccacagcctg accacgccac ggccaagcac ccggcagcct
    28441 ctgcggccac cggacgccca gcccagtccc gcaattgcag ccagcaggtc atgcccgagc
    28501 cggagcccag ttccttcggc aggtactttc accggatccc ggtgtgcagc acgtacacga
    28561 tcccgcacag cacctccgcc ggcgcttgag gaggagttcg ccgacgaggt tggtgaggcc
    28621 aggagcgtcg gagggatgcc gaccagggcg cgtgtgcgta cgaggtcagg cgtcaggatc
    28681 cctccgctca tcccgacgtc gggatcaggc tccgtagcgg ggcaggacgc cagtgtcgag
    28741 cggggacggc agaggggcgg gcagttcgac cacctctcca tactctccat ggacctgacc
    28801 gcagtactct ccgcccttag gacgggtatg cagagtccag cgaccggtac gagggtccag
    28861 gacaagcagg acggcgaccc cggctcgggc gtaccagcca ttcttgtcgg tgatgtcctt
    28921 cgccttctcc gactgggaga tcacctcgac agccaaggcg acatcaccag ggtcggccag
    28981 ccaggaatcg tcctcgtccc actccacggg caggaccgtc agatcgggcg tggcgtagtc
    29041 gtccggatcc tccggcatgg cgaccgagga catctcgtac ggcgccaggc ccccgggcag
    29101 ccgaggctcg atctgcaccc gcaggcgccg gatagtgcca gcgtgcttgc cgcgtggggt
    29161 gggggacatc acgaggctgc ctccgatgat ctcgacccgt agcccggtgg aagcttcgat
    29221 gcgttcggcg acctcgcgca ggtttccggg gcgcgggtgc agcacgggaa gggtcacagc
    29281 tgcccacctc ctcatcggtg gccgttcgat cactaccgta ccggtcgagc cctcgccacg
    29341 gcaggtaacc agagccgcgc ccaggcccgg cgccgccatc cgctacccgg caggccaggt
    29401 aaaccagccc gcgaacctca aggaacacga tccccacctc cgcgtacccg ccggggggac
    29461 aggggatacc aggggagcca caggggaaca cggatctctc gaatcccttt aaccacaagg
    29521 gatcccccac gtccatcccc tgccgcgtgc gcacttacct tcctgacctg cggaaacgcc
    29581 ggagaaccgg gacagacatc cccgtttgca tcctgctgga tccccctcga tcctgctcga
    29641 tctggcaccc gtgctgacac gtcagcacgc cccaccgatc gtttgcgcgg cgcaatctgg
    29701 ttcccgcttg aagctggcaa tttactggcc atcacttggg tagatcgcga tgcttaaacg
    29761 atgcgctaga gcaaactctg gtggcggcga ccggattgac cccgacgagg cgctgtccag
    29821 cggcctgatg ctgaaggcca gaaccccctg cttctcagac acgctgcctg tggtggggcg
    29881 gcacggtcat gatgcggcgg tactgggcga tggcggtgtc ctcgtccacg gggactgcct
    29941 cgacctcgac ccaggcgtgc gcggcgaagg gctgggtgcg cacgccggtg caccaggtgg
    30001 gccagctccc ccgcatgcga cacagcagtg tggtggccag ggagcgctgg aggcagcctt
    30061 cccccgcgca ggccaggctc agggatgtga tctcggtgcg ggcgcgctgg gcttcaccac
    30121 gggtggcggg gcgcgccccg cgtcgtacca ggagcaggat ggtgcggatg cgccccgggg
    30181 gaaggcggct gagcagccag gcgacggtga tggccagccg aatgggaggc cggcgccacc
    30241 atgcgggacg gtccgctgtg gggagggcgg tgtggacgct catgcggaag ccgtgttctg
    30301 tgtggagagg gatcgtggat caggcgagag agccaagacc gcgccgggcc aggtcggcca
    30361 gaaacgcgtt gacgtcggct gcggcttggg caggcgtggc atcagtgcct gccgtgagcc
    30421 ggtggaccgc ctcctcctgg ctcgctccgt tcaggagggc ggtcagggtg gcggagcccg
    30481 tcccgttcag ctcgaaatag ccgcccgtgc gctcgtcgag gatgaccatg ccggtgtcgg
    30541 tggtgacggc ggtgacatgt cggtgcagcc gaaaggccat gtcatgtgct cctggtggac
    30601 cgtacggtgc ttctggacgg ggtggcggca ggcagggtga ggcgtccgtg gtgcagccag
    30661 tgctccacca caagggtgtc ttcgaggtcg gcggagatac gcggtaccgg agtgtgcagc
    30721 gccgcgccca gggctgcggc gtccagcaga ccggcctggg ccagtcggga gcgctccacg
    30781 agctggttca gggcggcccg ctgttcacgc aagcccgcgt agaagtcggt gtcggtgctg
    30841 cccttcgtcg cgcgggcgag caggtgaccg ggcatcaggc cgtgcatggc ccgggccagg
    30901 agtggtttgt aggcgaaggg tgtcccacgc tcgtgagtac gcaccgcgag acaggcttcc
    30961 accacgcggt cgtcgaggaa cggcagcccc atccacggct ggtcgtactc ctggcgcatc
    31021 agccggtaga gctgggaaac ggcccgcagc cggtgcaggg tctggtgctg tccccggtcg
    31081 gcggcaaggg gcagcgcggt cgtcgcagct tcctccagga ggtcggcgac cagcagggct
    31141 gcccggcgcg tggcccatgg tgccatgcgc accggcggtc cccatcccaa cggcacgtgg
    31201 tgggaaggct cggtcggcgg gccaccgcgc aggcggcgag cctggtcgcg cagccactgc
    31261 gggtaggagc gtcggtcgac gagccctcgt agcgcgaggc tcaagggcca gcggcggacc
    31321 gaacggtggc cgcgcaggtg acggacggcg agaagcgggt gggccggcaa caggtcgccg
    31381 aggtaaccgg gcggggtctg gagaacctcg tcgccgccgt ggcccgcgag ttgaaggacg
    31441 actccgtgcc cgcggtagcg agcggcggtc gcgtcgaaca cggccctgcc tcgcagcacc
    31501 ccggacggag cgtccgccgg gctgcccggc tcgcccaggt tctcgtactg gccaggcagt
    31561 tcgtcgtcgg ccagcgacag cgccaccgtg tccggcagat ggcttcgggc caggttggcc
    31621 cagtgtgtgt cgtcgttggc cggatcccgg aacgccaagg tcatcgtgtg caaggaggcg
    31681 ccggcggcgc tcgcgaggaa cgccagcgcg gtggagtcca tgcctccgga caggtcacag
    31741 cccaccgcag attccggtgc ctgggcgatc cgcagggcca cggcctcggc gagagcggct
    31801 cgcagcgccg ccgcgccggt ctccaccggc cggtcgggaa gaggcggtga ccaccagggc
    31861 cggtgcgcgg atccgccgtg cgcgccgacc gtcagcgcgt cgcccggcgg gacggcgaag
    31921 acgccctgcc aggcggtgag accgtccagc agatgtgggg gcccgccggt gatgagtcgt
    31981 acggccagcc atcgctcgtc caggtcggcg cccgacaggt ccgccaggat gtccgcgcgg
    32041 tccgccgcga ccgtgatgcc gtgcatacgc gccgtgtaga cgcgacgcag accggaagcc
    32101 gtgccccgaa gccggaaccg gcccggtccc gagacggcca catgcacgct tcccgccgac
    32161 gctgaaggcc ccggaacgcc ttggtcagtg ctcaggggcg gcaggagacg ggcaagggat
    32221 gccacgtctg cacctgcgtg accgatgacg gccaccctca ggtcgcccgt cgacaggacc
    32281 tggcagtggc ccgtcggcac ccggccgacc aaccagggtc tgccggacgc gtgccgggcc
    32341 aggaccgacc cttcacaccg gagctcttcc agcacccgga gggcggcagg acagtcgggt
    32401 acggcgacga accactgcac aggagacctc acttcagacg ggcatcacgc ttcaaaacgg
    32461 ccgataccgg cttccctgta cttcccgtaa ccaccgcgcg tgtcgtgtgc gaacctcccg
    32521 gcctccgcga ccatcggcgg ctcgtaggcg accggctcct cgacagccac ccgctcctcg
    32581 ttcgtgagca ccttctggat ttccatgccc atccctcctc aggaatcagg acggggcgca
    32641 tccccgccgc tggaatgaat acctgccgcc atcttcctca aaccccctga acagacgctg
    32701 atttcagcca acatccatca attcttgcag ttcgaacccg agtccaaata ggcacgcatc
    32761 aaggcctgtt gaccaattat tgagcatgcc cgctcaggtg aggtaatcac caccgtcgat
    32821 cactttccac tcccaagagt gaagccttcc cgcatcacgg tcctacggtg cgccagtcgg
    32881 ctagcctggc acacatctcc ctttggccat acgggagttc ggcgcaccgg agcgcatcgc
    32941 gcccttcaag gatgaatcac cgcaacacca gagagagagc cgccatgcct cctgtcgttc
    33001 ccccgttcct gctagggctt gtctttgctc ccctggccaa gcgtctggtg aagccgctgg
    33061 tccgcggcac cgtcaagacg tcgatgagcc ttgtcatgga gttgaagaag gcagcgcacg
    33121 aggctggtga ggaactgcac gacatgaccg cggaggtcgc tgccgagttg atcggcgccg
    33181 aactccggga agaggaaaca gccgtcggca agccggtcaa gcctcggagc cctgccggct
    33241 cgggtactgc ggccggaaag gcccgctaag tcggccgacg gagcacggaa tgacgattca
    33301 gcatcctggg gacgacggca tggtcagatt tttctcgacc gcgccgccgt ccccattcgt
    33361 cctgccccag acaaggaaat gcgtgactga atacggtgac gttttggccg acatcacgac
    33421 cacgactgac atcatggaag agagcgactc cgctacgaat gtgctgtaca gggcggagct
    33481 ggtgctcaac aacggctcat acactctcgt cgtgcgggat ctcgtacacg gcacgctgcg
    33541 aatgaccggt gtgcccagga ggatggtggc aaagttcccc gcctaccttt cgatgctcaa
    33601 tcttcagcac gtggatgaat gaaccgaact gccttcggcg gccggctcgg ggacaggatc
    33661 cgggacggcg ggcagccgga gccgctcgcc tcgctccagc cgccaccgga tccaggtgag
    33721 cagcaccggc ctgggcagca gggtgtagac gcgggtcgga ctgcgcttga cggcgagggc
    33781 gcgcagcggg cgcgggcgga gcaggaagac ctgggcgaac cggaccaggg accggcggtc
    33841 ggcggcggcg aggtcgcaca gcaggtcgtc gcagagccgc cgccagactt cgtggaggcg
    33901 ggcgcgggcg gcttcgacgc cgacggccca gacacacatg cggtagaagt tgcaggagtc
    33961 gtcggccacg tccttggcat agccgacaac gtcactgatc agttctccca tcgcgtgcat
    34021 gtgtcccgcg agccggtcga acgactcgtc cccgggcagc ccggcgaggc gtcggccgaa
    34081 ccccgtcatg atccgcacgt cggacgaccg cccgtgacag gcacgcacga gatcgtccac
    34141 gctgtactga gcgcggcggc tcatggtctc ggtctcccag cgggcgtact cctccagcgc
    34201 gcgcagatcg gcgagtgcct cggcggtgtc acagccgtat ccgcgcagca cctcctcgat
    34261 gccgtcgcgc caggcggtgc ccgccggagg gccgtccgcc tgctcccgct cgacggcgag
    34321 atcgccgacg tagaccagcg cctccagatt gagcagcggg ggccagtagt agtccagcgc
    34381 gtcgtgcgga cagccgagga gacgcagggt gtggacgcag tgcagcgtga cggcaccggc
    34441 cttgagctgg tgccggaggg tgacggcggt gcgctcccag gccatggggg gatcggcgga
    34501 caagggccgc tcccaggcgc gctcggcggc gccccgagca ccgcgcgaca ccagcggacg
    34561 gcgcgccttc gcactcttcg tggcggtcat acgagccttc ctcggcgacg gggtgaacgg
    34621 gcggccggcg cggacactcc gccgccagga cgacggacac cgtaatcacc gcaacagcgc
    34681 caactggcat agaacatagg catgttcacc acatcgagtg gcgtgcacac cctgcgagtt
    34741 tttgccgccg agcgcatgga aatgccccgt gcggtgccag tccgacaggg gccggcaccg
    34801 ccttcgaaag gagtaccaat catgttcctt cccgactacg gcaacccccg cgaccccggt
    34861 tccgatgacg ctcccgctct gcgctggcag gcggaggtct acgagggcga cgaggcctga
    34921 gcggcacctg cccctccggg acaccccgtg tgaaccgagg aacggcgggg ccggcgccta
    34981 cctggccccg ccgttcttca catccgtacc ccctcccgcg cgcccgagga agcaccgtgt
    35041 tgccagagac caccagcgtc cacccgcccg ccgcccgcga gaacctcgtc gagacggtgc
    35101 acgggcggcc ggttgccgac ccttaccggt ggctggagga cctgaccagc gacgcctcgc
    35161 gcgcgtgggc cgaggcccag gacaccctgt tcgccgcgca ccggacggcc tggccggacc
    35221 gggacgcatg ggacgagcgg ctgaaggccc tgtcggtgac ccgtcgggtg tccgcgccgg
    35281 tctggcgcgg cggacggcac ttcaccgaac ggcatctgcc cggccgcgac caggccgtgc
    35341 tgtacgccac cggggcggac ggcaccgagc ggttcgtggt ggacgcgggc acactggcgc
    35401 cgcagggccg ggtacggctg gccgggtggc ggccctcctg ggaaggcgac ctggtggcct
    35461 gtcagttcgc ggtggacggg gccgacatca cccggctggt ggtgtacgcg gccgacggcg
    35521 ggggagccgt cgatgagccc gtggaggggc tgcggcactc gccggtggca tggctgcccg
    35581 gcgggcaggc cttctactac gtgggccccg cggccgaggg gccggacggc atgctgcggg
    35641 tcaaactgca ccgcctgggg cggcccgccg gggaggatga ggaggtgttc ggtgaacagg
    35701 ccgacggatt cgcgtacttc gggctgacca tcacgcccga cggcgatcgg ctggtcgtct
    35761 ccgtggcccg cggaatcgcc catcacaacg acctgtggct ggccgagacc ccggtgaacg
    35821 accccgcgcg gccgacgtgg cagcgcttgg tggacggcac ggagaccaag gcgctcgcct
    35881 cgatccggct gcaccgggac ggcggcggac gcctccacac cgaccggggc gcgccccgcg
    35941 ggaggatcct cgtcacggac cgcacagcgg cgcgcggtga cggctggcgg gaactggtac
    36001 cgcaggaccc ggacgccgct ctcgacgaca gtgtcctgct ggacgggctc gctctcgcgg
    36061 aaccactgct gctggtgtgc tggagtcggg ctgccaccag ccggatcacc gtgcaccggg
    36121 ccgcggacgg gaaacgcatc ggggaggtcc cgctgcccgg cagcggaacg gtccgggcgc
    36181 tgcgggggcg tcccgaaggc ggccacgagg cgtggttcac gtacaccgac ttcggcaagc
    36241 caccggctgt cttcgtcttc gacgcggtca gcgggcgggt cgcaccgtgg cccgggcgcg
    36301 gtgcgccccc cgggccccgg gcgtccgtgg agccgaccgg ggcacccggc tccacggcgg
    36361 agctgctcac cagtcaggtc cggtacgagg ccgacgacgg cacgccgatc ctgctcttcc
    36421 tcctcagccg cgccgaccag ccgctcaacc cgcccgccgg gccgccccgg cccgccctgc
    36481 tcaccgccta cggcggcttc ggcgtcccga tgcgccccgc ccacacccct tccgcgcgag
    36541 cctgggccca agccggcggc gtgtacgcgg tggcctgcgt acggggcggc ggcgagcacg
    36601 gcaacgcctg gcacgccgcc ggtcgtggcg ccgccaagtc ccgtgccgtg gacgacctca
    36661 acgacgccgc ccggtatctg atcgaccggg gcatcaccgc gccggaccgg ctggccgcga
    36721 ccggccagtc caacggcgga ctgctggtga ccgccgccct gacccgccgc cctgatctgt
    36781 acgccgccgt cgccgccatc gggccactgt gcgacatggc ccgctacgag cgcttcggca
    36841 tcggtcacac ctggacagcg gagtacggga ccgccgtcga ccccgggcag ctcgacgcac
    36901 tcctcgccta ctcgccgtat caccaggtac gtcccggcag ccgctacccg gccgtcctgc
    36961 tctgcggcgc cgacaccgac cagcgcaccg gagcccagca cgtgcgcaag atgtgcgcgg
    37021 cgttgcagca cgccacagcc tcccccgctc cggtcctcat gcgccgtacc acgaccggcg
    37081 gacacgcaca cgcgtcagca ggaacggcac acgatctcac cgcagacgtc accgccttcc
    37141 tcgcccacca caccggactg cccgcgccga cgtccgcgac cgccgacgga tcgccgcgtt
    37201 gatccctgag cgagtcgccc agcccgccca ccccgcccga ggcggagaga agcagagaga
    37261 accggtgatg cccgcgtgtc ccgctacgtc accccgcccg cagaaccgca cggccatcag
    37321 cacccggtcc gcggtccgct gaggctccgg tcggccgtgc ccgggcggca gcggtgggaa
    37381 gctcccgtcc tcgccgggcg cccccggctc gccgggctgc tcaccgccgt actgggcaaa
    37441 agccccggtg tcaccggcgt ccgagccagc gcggtgaccg gcagcgtgct cgtacaccac
    37501 gatccggcgc tcggtgcggc ggatatcggc gcacagctcc gggcggtcct ggacgacctt
    37561 ctgcgacagg tggggacgca gagccaggtc ccccaaccgt cggccgagcc agtccggacc
    37621 cgtgaacagg ctggtgatcc ggccggggct catcaggcca cccggtccgg tgtccgcccc
    37681 cgcatgctgg tggccggcgg tgccgcggcc tccctcgccc tgggcggctc cgggctgctc
    37741 ctgggcccct gggtggctct gggtgcggtc ggcgccgcca ccacgctgct gatccgccgg
    37801 gcctggcatg agacgagcga cccacgaaag ctgcccgcct caccgctgaa gcccgccgag
    37861 gcggcccgtc ccgtcgggaa cgccggcgca cctccgctgc tgcgcctggc caggaggcac
    37921 cggcgccgga tcggccgcgc cgcaggactg tcggccgccg ctgaactcgc cgaactgggc
    37981 gtcttcacca gcctcggcgc gctgccgcta ctcctcgccc gcggcagcag cccggtgctc
    38041 accgcgctgg gcgtgaccgg aaccctcccc cagctgggcg tgctcaccgc cgtcgccgcg
    38101 ctggcgaagc tcatccaggc ggccctgtcc taccgggccg acctcgcctg gcgcaccctc
    38161 ggtcaggacg tggaacacga gttgcgcagc gaggtgtatc cccatgtaca acggctgccc
    38221 ctgcgggacc tggagggcga gcggaccacg cggatcgccg gtgtgctgag cgcggacatc
    38281 ccacacgtcg gcgccttcct cgcccacggc cccggcgaac tggtccagct cgccacctgt
    38341 ttcctggtga tggcgcccgc ctttctcctc ctcgcccccc ggctcgcctg ggccgccttc
    38401 ctccccgtcc cggtcatcac ctggctctcc ctgcggcacc actcccgctc cgggcgcgcc
    38461 tacgcggccg tgggcgaccg cagggtccgg ctgaacagcc aggtcatcaa caccctggaa
    38521 ggcagtgcca ccgtcaagag cttctgcacc gaggccgagg aggccgcccg tgtggagcgg
    38581 ctgagcgacg cgtgccgcaa cgacacccgg ctcaacgacc gggagacggc tcggcacatc
    38641 cagaccgtcg gcacgtgtgc cagcctctcc ctgctcggta ccggactgct cgccgcccgc
    38701 gacgtgttcc ggggcactct gtccctgagt tccttcaaca ccctgctcgc cctgcccagc
    38761 ccggtgctgt atcggctcac ccggatcggc acgaccttgg agcagtacca gcacacactg
    38821 gccgcgctcg accgtgtcga acacctgcgg aacctgccga ccgagccgga cgagggcgga
    38881 cgccctctgg atcccggacg ggtcgagggt gagctggtac tcgacggggt caccttcgcg
    38941 tacccggggc gcccccctgt gctgcgggac acccggttgc gattcgtgtc cggccgtacg
    39001 accgccatcg tgggtgcgac cggggccggc aagaccacca tcgccaaact actcatgcgg
    39061 ttccaggacc cggtggcggg ccggatcctg ctcgacggcc aggacatccg ggagctacgc
    39121 ctgcaggacc tgcggcgctg catcggtttc gtcgcccagg acgccttcct gttcgacggc
    39181 acgatcgccg agaacatcgc ctacggcacc ccgcacgcgg agcacgcagc catcgtcggt
    39241 gccgcaggca tcgcgcaggc gtccgggttc atcgaagcac tgccgcaggg gtacgacacg
    39301 gtggtgggcg agcggggagc tgcactgtcc ggcggtcagc gtcagcgcat cgcgctggcc
    39361 cgcaccatcc tcaaggaccc tccggtcgtc atcctcgacg aagcgacgtc ggccgtcgac
    39421 aacgacaccg aagccgccat ccagcacgcc ctccggaact tcactgccgg ccgcaccacc
    39481 gtggtcatcg cccaccggct ctccaccatc cggcacgccg actggattca cgtcatgaac
    39541 gagaacggga ccatggtgga ggagggagcc caccaggacc ttctcacgca agacgggcag
    39601 tacgcgtcgc tgtggcgact acagaccgga atgcctgagc gggaccccga ggatgccggg
    39661 agagtactgg tcacggccac acattgacgc cctgctcaac accgcgaact cctggatcag
    39721 agagcggctc gacgtgcccc ggattcggcg gacgcggtgt tcagatcccg gacggcgaac
    39781 acgccgtgca cgccttgccc gcctcagctc ggggcgccct gaagggcaga acgacgggcg
    39841 cgaccaccag ggcaactgcc gcatgcagca gttgttccgg cggtcgcggc cgggccggga
    39901 tttcctggtc gctcccgacc ccgccgcgga ctacgcctgc gcggactacg tgtgcacggc
    39961 cgaggcactg tccgggtcga ggctgtcgat cttcacgtag aggtcgtcct ggttgccgat
    40021 gtcggggact gccacaccgc tgaccgaagg aacgaagcag accgcggaat ggcgcaggtc
    40081 cgctttgcca ccgccgtcgg tccgggcatt tgtcagcacc gccgtgctga cacgtcaaca
    40141 cgggaaccgg gacaaaaaca cccccctgac agcgtttccg caggtcagag gggtatctga
    40201 ttgtggagcc taggggagtc gaacccctga catccgccat gcaaagacgg cgctctacca
    40261 actgagctaa ggccccggga agcagcgacc tgccggaggt gtcgcgttcc ggcgggtgcc
    40321 gcagaccaga gtaccgggtc acccccggtg ttccgcaaaa agatgggggt ccccgcagat
    40381 gaccactctc cgtaagatgc tcgacgtggt tcgctacagc gaaccgcggt ttttcagggg
    40441 aagcgatggg gagacgcaat ggacgccgca cagcaggaag ccaccgcgag agcgcgggag
    40501 ctgcagcgga actggtacgg agagccgttg ggggcgctct tccgtaagct catcgaagat
    40561 ctcgggctca atcaggcccg tctcgcggcg gtcctggggc tgtccgctcc gatgctctcg
    40621 cagctgatga gcggccagcg cgcgaagatc ggcaatcccg ccgtggtcca gcgggtgcag
    40681 ctgttgcagg agctggcggc ccaggtcgcg gacggcagcg tgagcgccgc cgaggcgacc
    40741 gggcgcatgg aggagatcaa gaagtcgcag gggggctccg tgctcagcaa caccacccag
    40801 accacgagcg gttcgggcgc gccgacggtc aagcgggtgg tccgcgagat ccagtcgctg
    40861 ctgcgctcgg tggccgccgc gggcgacatc atcgacgctg ccgacagcct cgccccgacc
    40921 catccggaac tggcggagtt cctccgcgtc tacggcgccg gccgcacctc cgacgccgtc
    40981 gcgcactacc agtcgcacca gaactagcgg ccacggcccg gttcacggag gaggtccggg
    41041 agccgggccg gggcccaggt ccatgggggg atcgggggac cagtcctcaa gcggggacgg
    41101 ggtcgtatca ctcatctcag tcatctcact gatctcagtc attgcggggg agagaccggg
    41161 gaagagacgg gagggagaga ccgggggaag atcagggaga aggtcagggg gaagcgcggg
    41221 aagcggggaa gtaaggggac agagggactg gcgggggcca gggggaggag tgatgggctg
    41281 tcatgggtga ggtcttcgcc ggacggtacg agctggccga cccgatcgga cgcggtggcg
    41341 tgggcgccgt atggcgcgcc tgggaccacc gccgacggcg ctatgtggcc gccaaggtgc
    41401 tccagcagcg tgacgcccac tccctgctgc gcttcgtccg cgagcaggcc ctgcggatcg
    41461 atcacccgca tgtcctcgcc ccggccagct gggccgccga cgacgacaag gtgctcttca
    41521 ccatggacct ggtcggcggc ggctcactgg tccatctcgt cggcgactac ggccccctgc
    41581 cgcccgcgtt cgtgtgcacc ctgctcgacc agctcctgtc cggtctcgcc gccgtccacg
    41641 ccgagggcgt catccaccgg gacatcaagc ccgccaacgt cctcctcgaa gccaccggaa
    41701 ccggccggcc ccggctgcgg ctgtccgact tcggcatcgc catgcggctc ggcgaacccc
    41761 ggctgacgga gaccaacctc gtggtgggca cgccgggtta tctcgcgccc gagcagatgc
    41821 tcggctgcga acccgacttc cccgccgacc tgttcgccgc gggcctggtc gctctgtatc
    41881 tcctcgaagg cgccaagccc gacgccaagg cgctcgtgga gtacttcgcg gaccacggga
    41941 cgcccgggcc gcccaagggc atcccggagc cgctctggca ggtcgtcgcg accctgctcc
    42001 agcccgaccc ggacgcgcgc ttccgcaccg ccacgggtgc gcgcaaggcc ctcgccgccg
    42061 ccgtgg
//
