LOCUS       NZ_CM002285            21200 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3315190
            Orig. end                         :: 3336390
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21200
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="23"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21200
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21200
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11200](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11200)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(674..685)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    1771..1785
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(1944..1960)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.08"
                     /tool="antismash"
     gene            complement(2363..2794)
                     /locus_tag="M878_RS64010"
                     /old_locus_tag="M878_15170"
     CDS             complement(2363..2794)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674759.1"
                     /locus_tag="M878_RS64010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15170"
                     /product="ATP-binding protein"
                     /protein_id="WP_031224934.1"
                     /transl_table=11
                     /translation="MGGLAGLGVIGVIDTDGDCAEWSFPAEPGAVRTARAAVRGQLHGW
                     DLDCLADLAALLVSELVTNSLRYATGPIGVRLVRPVGLADTLLVEVSDPLPDPPRERVA
                     RDEDESGRGLQLVAGSSRRWGTRPGVSGKTVWFELAVPG"
     gene            complement(2921..3454)
                     /locus_tag="M878_RS64015"
                     /old_locus_tag="M878_15175"
     CDS             complement(2921..3454)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674758.1"
                     /locus_tag="M878_RS64015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15175"
                     /product="(deoxy)nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="WP_023547019.1"
                     /transl_table=11
                     /translation="MTDRMTPEADRIVVVGAALLDGGRLLAARRSAPADLAGRWELPGG
                     KVEPGERPEDALARELREELGVDAEPVERVPGQWPLRAPYVLHVWTARLRPGSPPPRPL
                     QDHDELRWLTPDRIWEVAWLDQDVPAVREVTARSKAGRSPAGGAGLKRSAAPPPGATSR
                     NGPAPARRPHHPSS"
     gene            complement(3494..3688)
                     /locus_tag="M878_RS64020"
                     /old_locus_tag="M878_15180"
     CDS             complement(3494..3688)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072018.1"
                     /locus_tag="M878_RS64020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15180"
                     /product="SPOR domain-containing protein"
                     /protein_id="WP_023547020.1"
                     /transl_table=11
                     /translation="MSEGTVSLPWIVIRQDDNGNRYRVGRYATRAEAQKIADSLDDDRG
                     HKQLYWVERIGQNGDGGRN"
     gene            complement(4314..5066)
                     /locus_tag="M878_RS64025"
                     /old_locus_tag="M878_15185"
     CDS             complement(4314..5066)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998196.1"
                     /locus_tag="M878_RS64025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15185"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_023547021.1"
                     /transl_table=11
                     /translation="MTFGEQPAYLRVAGDLRKKIVDGSLPPHTRLPSQARIREEYGVSD
                     TVALEARKVLMAEGLVEGRSGSGTYVRERPVPRRVARSGYRPAGGATPFRQEQADAAVR
                     GTWESSSEQAEAGAAIADRLAIDVGDRVMRTKYLFREAGEPMMLSTSWEPLAVTGRTPV
                     MLPEEGPLGGMGVVERMRAIDVIVDNVTEEVGARPGLAEELHVLGGVPGHVVVVVQRTY
                     YASGRPVETADVVIPADRYRVAYHLPVK"
     misc_feature    complement(5079..5097)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.0"
                     /tool="antismash"
     gene            5509..5919
                     /locus_tag="M878_RS64030"
                     /old_locus_tag="M878_15190"
     CDS             5509..5919
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS64030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_15190"
                     /product="hypothetical protein"
                     /protein_id="WP_031224935.1"
                     /transl_table=11
                     /translation="MRVGTLTGGRAGGDAVTGDRGGAEVVRAVNGLTRHWAAAAHDGTV
                     FSAAGVRPLPGFRTAAITTFVAAGAGALAKPRYATTRIDAACDRPFDRPFGFLALHRHA
                     RLVPAAGWVTDPPPYPEDPYLVTGKAAQEDDE"
     gene            5916..7136
                     /locus_tag="M878_RS64035"
                     /old_locus_tag="M878_15195"
     CDS             5916..7136
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267960.1"
                     /locus_tag="M878_RS64035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15195"
                     /product="serpin family protein"
                     /protein_id="WP_023547023.1"
                     /transl_table=11
                     /translation="MSKVTAETVRQVNGLTARWAQALPEGTAFSAPGVWPLLGFLADGA
                     TGPARAELAGALGVPAEQAAAAARELLLALASVSGLDAALGLWSHQGLALREEWRAGLP
                     AGTYGVFGDDLVTAQERLDAWAAERTGGLVERMPVTLTRDARMVLASALALRTTWRQPF
                     DQLPLRPDAGPWQGRTLRGLHRRSPRPDRVGVTGTPDGFVTALTVPGDNGIDVHLVLGE
                     EHMTPGQVLNAGVGIVERALPLTGGGALPHGHVGPGLYVEQQPAVEPTSLTLDVRTVAY
                     EVRADHDLLALPGLFGLTAAADARHGHFSGISDYPLAIGQARQSALAQFGPLGFRAAAV
                     TAVMPEAGGLPPQYRYESTVVRVVFDRPFGFLAVDRESRLVLVAGWVTDPAPEPVMSFP
                     GAVPPGL"
     gene            complement(7099..7539)
                     /locus_tag="M878_RS64040"
                     /old_locus_tag="M878_15200"
     CDS             complement(7099..7539)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737292.1"
                     /locus_tag="M878_RS64040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15200"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_031224936.1"
                     /transl_table=11
                     /translation="MPASERLGSHLKRAEQALNATKAAVLKPAGLTVAQYAALLHLDDN
                     PGISAAALARLCGVTPPTMNTVLKNLQDRDLITRSPHEWHKNVLETRLTDEGRAVLTAA
                     DTSAVRVERALAAEFTEAERDALTGLIARCVRVLEEQRPGSS"
     misc_feature    complement(7586..7601)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.77"
                     /tool="antismash"
     misc_feature    complement(7619..7637)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.98"
                     /tool="antismash"
     misc_feature    7633..7649
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            7694..8677
                     /locus_tag="M878_RS64045"
                     /old_locus_tag="M878_15205"
     CDS             7694..8677
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737293.1"
                     /locus_tag="M878_RS64045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15205"
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="WP_023547025.1"
                     /transl_table=11
                     /translation="MSRSIHRRTFLSGAAAAAVAVAAPRATAATGPRISTAFTLPGDRA
                     YPEGIALDPRTGDAYVGSYTTGAIYRAAAGSRTAEVFLPAGTDGRTTANGLKADRAGRL
                     WVIDHTTGVDVYDLSDRSLLARFEVPAGDPHFLNDLVITADGTAYVTDSVRPVVYRITP
                     ADLARAHGGRAPLTARYDLSGAVPSHGPDAYTLNGIAADATGRRLFVVDMTGGGLYRVD
                     VTDGSILQVTLHGGDLVHGDGLDLSHRTLWAAHNKSNTLTRWHLSPDGTEARLLRTLTD
                     PALQIPTTLAHTPRGLLVVRSQFDKGGPMGSGTPTTPFTVARVTGM"
     gene            complement(8760..10004)
                     /locus_tag="M878_RS64050"
                     /old_locus_tag="M878_15210"
     CDS             complement(8760..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522324.1"
                     /locus_tag="M878_RS64050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15210"
                     /product="hypothetical protein"
                     /protein_id="WP_023547026.1"
                     /transl_table=11
                     /translation="MTDTAAEGLPRIEPSARVLLHDLAVQRERDEWIVGRITTRTFVAM
                     PAAGARAVELLGEGLSVARTAETLRDETGEEFEITEFVRDLAALGFVARIGECPIPDAE
                     PPRASLPWLRPHHVRFALHPVLPVFAGALLAAAVVVLIRRPGLLPGYRDLLWSPHGSLV
                     LLTGAAAGWALVLAHELAHLVTARAAGVPGKMRLGTRLQFLVMQTDISGIELAPRRHRL
                     TAYLAGIALNLSVASSLVLTLALASPGTTVRRLLSAALLLALMPLPFQLMVFMRTDLYF
                     VVQDVTGCRNLYGDGLAYVRYVFRRAVRSLRPGRTTGTDDPSSRLPPHERRAVRLYSAV
                     LVAGTVACLTFMAAVTLPVDVTLLIRAARGLGPGHGLAGNTDSAAVLITLGGVNVLWLV
                     TRWRDRGSRRSAGLT"
     gene            complement(10001..11200)
                     /locus_tag="M878_RS64055"
                     /old_locus_tag="M878_15215"
     CDS             complement(10001..11200)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387620.1"
                     /locus_tag="M878_RS64055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15215"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_031224937.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 5.8e-30,
                     bitscore: 102.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 4.2e-40, bitscore: 136.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPAMRRPRIKPEHRAYRTVDGHVRIGSVVHGIGAEVKDPDGWV
                     WTLVEAMDGTRNAGEIVAEVSRRHPGLRPPAPDIVQAMTDLTMAGFVEDAGAAPPAELS
                     ERERERYSRGMTLLRWMDLRPRESSWEPQVRLRRARVLLIGVGGTGGAAARDLAASGVG
                     RLHCVDPDVVELSNLNRQTLFSERDLGTPKIDAALTALRALNSDTTVTGERREVRGPAD
                     LEDLLTGAPDSSGGGSGYDVLLLAADRPAAIRSWTNRVCLASGTSWAEAGYRGPLVSVG
                     VFTPGRGACWECLRIAEAERRDLRLAPGQDEDVASPRMPWNPVNAVTAGLSGGLLAHAA
                     ITLLCGVPPVGPGHRFGLNLMVPGDAIEQRSDRRPDCPACRAEPAGPEPAAHRGPGDLS
                     "
     aSDomain        complement(10892..11185)
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M878_RS64055_Pantocin_Microcin_RRE.1"
                     /evalue="1.80E-32"
                     /identifier="RREFam017.1"
                     /label="M878_RS64055"
                     /locus_tag="M878_RS64055"
                     /protein_end="103"
                     /protein_start="5"
                     /score="102.3"
                     /tool="antismash"
                     /translation="MRRPRIKPEHRAYRTVDGHVRIGSVVHGIGAEVKDPDGWVWTLVE
                     AMDGTRNAGEIVAEVSRRHPGLRPPAPDIVQAMTDLTMAGFVEDAGAAPPAEL"
     misc_feature    complement(10985..10987)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11423..12733
                     /locus_tag="M878_RS64060"
                     /old_locus_tag="M878_15220"
     CDS             11423..12733
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015658078.1"
                     /locus_tag="M878_RS64060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15220"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_031224938.1"
                     /transl_table=11
                     /translation="MNRYPTVAEVTESARQLVSRFPGAGRLRRIGTSRAGRPVLMLSVG
                     HGPRHILVVARPHPDEPVGAATALALAERVARGDRLSAATDPAIVTWDIILCLDPDGAA
                     LSHGIEEATAGPGHTLDTYYRTAYRPVAAEQPEWAPIESQQLPESQALFRVIDELRPFL
                     QCSLHGVEAGGSWVQVTRDLPELAVPFQASATELGIPVQHGTFDALYWENPSPGVYVLP
                     PPDSTDRLAAGSENIGLSTWCAPQRYGGVTAIIEVPMWATDLADDLSPHPEAAHVLREL
                     AGLVRERGRQVTAVLDKARAFLPPAQDSPPRRVLEWMADGLYDLVADSWEPLARQAAAA
                     SHPDDPHRLTTAQVCALDIVARRQPLRAAGLLLRLLKTTDDAAAPGLHRDLDELFTAWC
                     TDFETALRLRWVPVHHQAEHQARTVVAAAETALTALQ"
     gene            12816..13397
                     /locus_tag="M878_RS64065"
                     /old_locus_tag="M878_15225"
     CDS             12816..13397
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326865.1"
                     /locus_tag="M878_RS64065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15225"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_023547029.1"
                     /transl_table=11
                     /translation="MTALPDWMRPPREEGWFAEDLDRLPEAPRHTELIDGALVFVMSPQ
                     RWWHGHLVTMLTVALMEQAPGDVRVGREMTIKLDERNRPEPDLLLTTADYDGDRTWFAP
                     DEVRLVIEVVSPESAHRDRTVKLRKYAEAGIAHYWCIEDENGAPVVHVYELDEPTGAYA
                     PAGIFRGTLERPVPFQINLDLDKLTPPRGN"
     gene            13597..13866
                     /locus_tag="M878_RS64070"
                     /old_locus_tag="M878_15230"
     CDS             13597..13866
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014628308.1"
                     /locus_tag="M878_RS64070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15230"
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_023547030.1"
                     /transl_table=11
                     /translation="MTQPLPTESIRDVRAHLAEVVERADRDDVPTVITRRGKEVAAVVS
                     IDMLRKYQEWEEREINRIIDERMANPAPGIPIEDIMRETLARSE"
     gene            13859..14122
                     /locus_tag="M878_RS64075"
                     /old_locus_tag="M878_15235"
     CDS             13859..14122
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /GO_process="GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019434847.1"
                     /locus_tag="M878_RS64075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15235"
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_023547031.1"
                     /transl_table=11
                     /translation="MSEYRTAFRPEAQAELRKVPRDMTLRILAKLTELESDPLGFNTTA
                     LVSQPDRRRLCVGDYRVIYTIDNGELVVWVVHVGHRSTVYDT"
     gene            complement(14314..15732)
                     /locus_tag="M878_RS64080"
                     /old_locus_tag="M878_15240"
     CDS             complement(14314..15732)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011211317.1"
                     /locus_tag="M878_RS64080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15240"
                     /product="ATP-binding protein"
                     /protein_id="WP_023547032.1"
                     /transl_table=11
                     /translation="MVDFVGRRQELATLERELQKVAAGVGGERPGRCVMLRGRRRVGKS
                     RLVERFAERSGAPFLFYAATGASPRDDLARLARDAQASTLPLAGLVAAARPESWDAAFD
                     VLAAALPADRASVLVIDEVPYLMDTDGAFEGMLQRAWDRVLETKPVLLVLIGSDLSMME
                     ALNSYGRPFHQRGREMVLGPLNPAEVGQMLGLDPAEAFDAALVTGGLPLICAEWPRGAG
                     LWDFLGEALSDPVSALLVSAERSLAAEFPPQAQARTVLAAIGSGERTFTNIARAAGGIG
                     ATPLQRALELLTDKRIVAGELPVSLRPSKDRRYRVTDPYLRFWLHLLGPSMEEIERGRG
                     DLTLARIRENWTSWRGRAIEPLIREALARILPDGQLPAAPAVGGYWTRTNDVEIDIVGA
                     DRAPIAKELLFVGSIKWLEQSPFDRHDLAALHRHRAALTDEPVPVVAVSRSGVDCPGLD
                     AAYGPGHLLTAWPL"
     misc_feature    complement(15752..15765)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.17"
                     /tool="antismash"
     misc_feature    15797..15811
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(<15849..>16007)
                     /locus_tag="M878_RS94235"
                     /pseudo=""
     CDS             complement(<15849..16007)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103101.1"
                     /locus_tag="M878_RS94235"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVLFTDDVRCPVHVEDLAAALW"
     gene            complement(16172..17260)
                     /gene="ychF"
                     /locus_tag="M878_RS64085"
                     /old_locus_tag="M878_15250"
     CDS             complement(16172..17260)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="ychF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058470.1"
                     /locus_tag="M878_RS64085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15250"
                     /product="redox-regulated ATPase YchF"
                     /protein_id="WP_023547034.1"
                     /transl_table=11
                     /translation="MSLTIGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVG
                     VPDARLAQLASIFGSERILPATVDFVDIAGIVRGASEGEGLGNKFLANIRESDAICQVI
                     RAFKDENVVHVDGKVSPKDDIETINTELILADLQTIEKVLPRLQKESRIKKDIAPKVKA
                     VEEAKEILEKGDTLFAHGIVQGTERNELLHDLHLLTTKPFLYVFNVDEDELIDEDFKDE
                     QRALVAPAEAIFLNAKLEADLAELDEEEALELLQSVGQDEPGLATLARVGFATLGLQTY
                     LTAGPKESRAWTIKKGATAPEAAGVIHTDFQKGFIKAEVISFTDLLATGSVPEARAKGK
                     ARMEGKDYVMQDGDVVEFRFNV"
     gene            17592..18008
                     /locus_tag="M878_RS64090"
                     /old_locus_tag="M878_15255"
     CDS             17592..18008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674713.1"
                     /locus_tag="M878_RS64090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15255"
                     /product="DUF6542 domain-containing protein"
                     /protein_id="WP_023547035.1"
                     /transl_table=11
                     /translation="MARAARAVRGPRLPNPRLTGRGTGLFCVVAMFLLGCLDALLFDGY
                     MPVYGVLFLPVCVLTALWARAGDVLTAPVIVPIAFAVGLIPAADGNGGLLGRLMGLFTG
                     LATQAGWLYTGTLFAGVIVLVRRVRWVRGRRRRT"
     gene            complement(18059..18805)
                     /locus_tag="M878_RS64095"
                     /old_locus_tag="M878_15260"
     CDS             complement(18059..18805)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378270.1"
                     /locus_tag="M878_RS64095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15260"
                     /product="ROK family protein"
                     /protein_id="WP_023547036.1"
                     /transl_table=11
                     /translation="MQIFGVDIGGSGIKGAPVDLDKGDLAQERLKVLTPHPATPDGVAD
                     GVKQVVDHFGWTGPVGLTFPGVVTGGAMIRTAANVDKSWIDTDARALFTGRLGGLPVVV
                     LNDADAAGVAEMQFGAGRDRKGTVILLTFGTGIGSAVFVDGALVPNTELGHLELGGHDA
                     EKRASSKAKEDHELSWERWAQRVQKYLAHVEMLFSPELFIIGGGVSRKADKFLHLLDGI
                     KAEIVPAQLQNNAGIVGAAMRAAQLT"
     gene            complement(18835..19851)
                     /locus_tag="M878_RS64100"
                     /old_locus_tag="M878_15265"
     CDS             complement(18835..19851)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132045.1"
                     /locus_tag="M878_RS64100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_15265"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_106962831.1"
                     /transl_table=11
                     /translation="MGRMTASPGRRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVR
                     HEIVHNKYVVQTLEKKGAVFVERTEEVPPGNIVMFSAHGVAPVVHEEARQGRLATIDAT
                     CPLVTKVHKEAVRYAKEDYDILLIGHEGHEEVIGTSGEAPDHIQLVDGPEDVAKVEVRD
                     PSKVVWLSQTTLSVDETMETVDALKTKFPGLVSPPSDDICYATQNRQLAVKQMGAEAEL
                     VIVVGSRNSSNSKRLVEVAKLAGSREAYLVDFADEIDEAWLEGVTTVGVTSGASVPEVL
                     VEQVLEWLSERGYGDVEIVKAAEESITFSLPKELRRDLREEATTLVAERGGTGPSAE"
ORIGIN
        1 cgtcctccag gggacgggag gggtccgtga gggcgcccac gaaggcctgc aggccctcgt
       61 ccagagggtg gtcgcgggac tcgaccaggc cgtcggtgta gagggccagc aacgcgccct
      121 cggggagttc cacctcgacc tcctcgaagg gctcgccgcc cacgcccagc ggcatgccgg
      181 gcggcacgtc cagcatcagg gccggctcac cgggctcgac caggaccggt ggcagatgac
      241 cggcgttggc gaacgtacag cgtctggtga cggagtcgta caccgcgtac acgcaggtcg
      301 ccaggtagac ctcggagagg tcggcgtccc ggggctggcg ggccgtgcgc gtggcctgct
      361 ggacgccgcc cggggtgccg aggccgcgcg cgatctcgtc caacgcggag agcacctcgg
      421 ccggttcgag atcgaggagg gccaatgtcc gtaccgccgt gcggagttca cccatcgcca
      481 ccgccgcgcg cagacctcgg cccatcacgt cgcccaccac caacgccgta cggtggccgg
      541 gcagttcgat gacgtcgaac cagtcgccgc cgacctcggt cgccgcgttg ccggggaggt
      601 aacggcaggc gatgtccagg ccggaggcct cgggggcgcc cggcggcagg agcgaccgtt
      661 gcaggatcag ggcgcgttcg tgttcccggc ggtacaggcg agcgttgtcg atgcacacgg
      721 ccgcgcgtgc ggcaagctcc accgcgaggt cccggtcgcg gtcgccgaac ggctcgctgc
      781 ccttggtgcg ggcgaaccgg gcgaggccga cgaccgtgtc gtgggcgacc atcggaaccg
      841 ccagcgtgga ctgtacgagg ctcccgtcct ccgccgggac gcgttgcggg cgggcggtgc
      901 gcagggcgtc cgcgcagggt gagttgaagg ggaagtggtg gaccgcgccg accgcgacgg
      961 ggtcggcggc gccggtgagg ggcacgtccg agacggcgct cgcgaaggcg acgcggcgca
     1021 gttcggcgct gccgtcggcg aggccgggcg gggtctcgtc gccggtgagc aggccctggt
     1081 agaggtcgac ggtggcgagg tcgcagaagc cggggacgac gacgtcgagg agttcccggg
     1141 cggtggtctc caggtcgagg gagttcccta tgcgggcgcc ggcctcgttg agcagggcga
     1201 ggttgcggcg ggcgttggcg gcctcgcggg cggcggcccg gcgggcggtg atgtcggtgc
     1261 cgagccaggc gatgccgatg gggcgcccgg tgccgccgtg cacccggtag aggttgacgg
     1321 accagtgccg gcgttcctcg gagccgggga catggcccgt gacatgcatg tcggtgatgg
     1381 actggccgct ctccagcacc cgccgcaggg tggctgaaac ccgctcggcc tcaccgcgcg
     1441 gcagatagtc gtgcacgccg ttgccccggt ggtcgtccgg gctgccgccg aagatggagg
     1501 cgaaccgctc gttggcccga cggaccctca gatcgatgtc gatcagcagg aatccgaacg
     1561 gcgactggcc gaagatggcc tgcgaggcgg ccaggtcggt ctcgatgctg cgcagggtac
     1621 ggacgtccac gacgatacag acggcggcct tgtccccctc ggcggtccgg gtgggcatga
     1681 catagacctc ggccaggccc tcctcaccgc gcgtgccgtc ggccttgtcc ggcatccgga
     1741 agggtacgac cccggtccac tcccgcccgt cgaggatttc ggccatcttg cgctggccgc
     1801 gctcgcgcag gtcggggtcg atgaaggtct ctatcgggtc catgccgacg gcgcgtgcgg
     1861 cggggatgcc gaagagctgc tcggcgcgca ggctccactg gtcgaccagc ccaccggggc
     1921 tgatggagaa ggacgcgacc ttgatgtagt cgtagatcga accgggcgga ctgctctgcc
     1981 acatggcgtc gccgggtgcc gtggcggcct ccgcggcctg gttcctcgcg ccgtccgacg
     2041 ggtcctcgga ctccgtggcc ttcgctggta tctcgctcac gcgaaccgtc ccctccagct
     2101 caccgcgccc ggcaccggtc accggaggcg gctgcccgca gtatccagca ctacgacgcc
     2161 gcacgacacg gtgttcacga tcacagctcg gtccagatga tttcaggacc gttccgtgac
     2221 aacacttcca ctcttctaac cagggaacac gccctcgaat cacgcactcc ggagtcagcc
     2281 gcgcgcccgg ggcgcacggt ggactcacca acgcccgctg tacaccccct gctccccagg
     2341 tgcttccgcg cacgctcccg gctcacccgg gcacggccag ttcgaaccag acggtctttc
     2401 cgctcacgcc gggccgggtg ccccagcggc gcgaggagcc ggcgaccagt tgcagaccgc
     2461 gcccgctctc gtcctcgtcg cgggcgacgc gctcgcgcgg cgggtcgggc agcgggtcgg
     2521 agacctccac cagcagggtg tcggccagcc cgacggggcg tacgagtcgt acgccgatgg
     2581 ggccggtggc gtaccgcaac gagttggtga ccagctcact gaccagcaac gcggcgaggt
     2641 cggcgaggca gtcgaggtcc cagccgtgca gttgcccgcg gactgctgcg cgtgcggtgc
     2701 gtacggcgcc cggttccgcg ggaaagctcc actcggcgca gtcgccatcg gtgtcgatca
     2761 cgccgatcac tcccaggcca gcgagcccac ccatgtccgg tttcgtgggg ttaatgggca
     2821 catacccgat atcccggggg cagtaccgtg cgggagggcg cacagtggca caaacggcgt
     2881 acggggcgct ccgcgggttt cgccgcgcgc cgccgcgcgc ctaagaactc gggtggtgcg
     2941 gtcgtcgtgc gggtgcgggt ccgtttcggc tggtcgcgcc cggcggtgga gccgcagatc
     3001 tcttcagccc ggcgccccct gcggggcttc gccccgcttt ggatcgggcg gtcacctcgc
     3061 ggaccgctgg gacgtcctgg tcgagccagg ccacctccca gatccggtcc ggggtcagcc
     3121 agcgaagctc gtcatggtcc tggaggggcc ggggcggggg cgagccgggg cgcaggcggg
     3181 cggtccatac gtgcaggacg taaggcgccc gcagcggcca ctggccgggt acgcgctcga
     3241 cgggttcggc gtcgacgccg agttcctcgc gcagttcgcg cgccaaggcg tcctcgggcc
     3301 gctcgcccgg ctcgaccttg ccgccgggca gctcccagcg tccggcgagg tcggcggggg
     3361 cgctgcggcg cgcggcgagc agccggccgc cgtcgagcag ggcggctccc accaccacga
     3421 tgcggtccgc ctcgggtgtc atccggtccg tcatgggcgt catggggcgg agcctacggg
     3481 agggtgcgcg aggtcagttg cggccgccgt ccccgttctg gccgatgcgc tcgacccagt
     3541 agagctgttt gtggccccgg tcgtcgtcga ggctgtcggc gatcttctga gcctcggcgc
     3601 gggtcgcgta ccgcccgacg cggtagcgat tgccgttgtc gtcctgccgt atgacgatcc
     3661 agggcaggga gaccgtcccc tcactcatgg cccccaccgc ccgcgtcgct ccttctcgca
     3721 tcgccccgcc ctcccccacg ctcggccggg ctgacccgag gggacccccg tcccgtcccg
     3781 ggcctcggtc gcgccccgcc taaggaaacc gcaatccgca tatgcccgag cgtacgccca
     3841 acctttacgc agcgaatacg ccttttcaca aagaggtacg caaccagcca gaacacgggg
     3901 gcgcacagga gtgaacgcgc cgtcgtgagc gccaccgccc cgagtcgtag gcatatccga
     3961 gtgacccgtg gtcacctggg aaaacggctg gattgcagcg gccggccgac cctcggcgaa
     4021 ggtcgcggga cagggcgtgc gggtcagggc gcgccagggt gtgcgctacc tcaccgggag
     4081 gggcgcacgc accggcgcga aaggctccgc cgccacttca ccggcagact cacccctcac
     4141 cgaggggccc ggactacccc ttcgccgagg ggccgggtac ccctgcgccc taacggccgg
     4201 cccccttcac aggcaagccc gaccaccacc tcaccgacgg acccggccgc gcgaggagcc
     4261 gcacgctcca gacctggcct cgcgagagga gccgcacgct ccagacccgg ccgtcacttc
     4321 accggcaagt ggtacgccac ccggtaccga tcggccggaa tgaccacgtc cgccgtctcc
     4381 accggccgcc cggaggcgta gtacgtgcgc tggacgacca cgaccacatg gccggggact
     4441 ccgccgagca catgcagttc ctcggcgagg ccggggcggg cgccgacctc ctcggtgacg
     4501 ttgtccacga tgacgtcgat ggcgcgcatg cgctcgacca cacccatgcc gccgagcggc
     4561 ccctcctcgg gcagcatcac gggagtacgg ccggtgacgg cgaggggctc ccatgacgtg
     4621 gagagcatca tcggctcgcc ggcctcccgg aagaggtact tcgtgcgcat gacccggtcg
     4681 ccaacgtcga tggccagccg gtcggcgatg gcggccccgg cctcggcctg ctcgctgctc
     4741 gactcccagg tgccgcgcac cgcggcgtcg gcctgctcct gccggaaggg cgtggcaccg
     4801 ccggccgggc ggtacccgga gcgggccacg cgccggggca cgggccgctc gcgcacatac
     4861 gtcccggagc cggaacggcc ctcgaccagc ccctcggcca tcagcacctt gcgcgcctcc
     4921 agcgcgaccg tgtccgagac gccgtactcc tcacggatgc gggcctggga gggcagccgg
     4981 gtgtggggcg gcagcgaacc gtcgacgatc ttcttgcgga gatcacccgc gacacgcagg
     5041 tacgccggct gctcaccgaa agtcactggc cgctcccatc aggttgtaca gacagcaaca
     5101 gcctggcaac cgtgggttgt gccatgcaag caaaggccag agaatcactc gatgtgatga
     5161 cacggggcgt gggagggctt tacccaggca ctttctcccc cgtataggtc cgctcacacc
     5221 tggcgcgggg cggttgaggg agctgtagcc ccgcgggcat ggcgggtatg gcgcaacgcc
     5281 tgtggcccgt ccgactgttg ggggtacggc ggggccacgt acggactgtg cgggtgcggg
     5341 cggggtggct gaaacggcgc ttctggctgg tgggggccgg gggcggccgt agggaccccg
     5401 gtaccgtgct ccttggccgg gcggcggcga cgcgggaccg gtgaacggcc ggtggcccgg
     5461 ctgacgtacg actgggcaca tggtgagcgg ggcggaagcg ggggcggaat gagggtgggg
     5521 accctgaccg ggggtcgggc gggcggcgac gccgtcaccg gggaccgcgg gggcgccgag
     5581 gtcgtccggg cggtgaacgg gctcaccagg cattgggcgg cggccgcgca cgacggcacg
     5641 gtcttctcgg cggccggggt ccggcccctg ccaggcttcc gcaccgccgc gatcacgacg
     5701 ttcgtggcgg ccggggccgg cgcgctggcg aagccgcggt acgccacgac gcggatcgac
     5761 gccgcctgcg accgcccctt cgaccgcccc ttcggcttcc tcgccctgca ccggcacgcg
     5821 cggctggtgc cggcggcggg gtgggtgacg gatccgccgc cgtatcccga ggatccgtac
     5881 ctagtgaccg gcaaggccgc gcaggaggac gacgagtgag caaggtgacc gccgagacgg
     5941 tccgtcaggt gaacgggctg acggctcgct gggcgcaggc cctgcccgag ggcacggcgt
     6001 tctcggcgcc cggggtctgg cccctgctgg gcttcctggc cgacggcgcg acaggcccgg
     6061 cgcgcgcgga gctggccggg gcgctgggcg tgccggccga gcaagcggcc gcagcggcac
     6121 gggagttgct gctggcgctc gcctcggtgt ccggcctgga cgcggcgctc ggcctgtggt
     6181 cgcaccaggg gctggcgctg cgcgaggagt ggcgggccgg gctgccggcc gggacgtacg
     6241 gggtgttcgg ggacgacctc gtcaccgcgc aggagcggct ggacgcctgg gcggccgagc
     6301 ggaccggcgg gctggtcgag cgcatgccgg tgacgctgac ccgggacgcg cggatggtgc
     6361 tggccagcgc cctcgcgctg cgcacgacct ggcggcagcc cttcgaccag ctgccgctca
     6421 ggccggacgc cggcccctgg cagggccgca ccctgcgtgg gctgcaccgg cgcagcccac
     6481 ggccggaccg ggtgggcgtg acgggcacgc cggacggttt cgtcacggcg ctgacggtgc
     6541 ccggcgacaa cggcatcgac gtccatctgg tgctcggcga ggaacacatg actccggggc
     6601 aggtgctgaa cgccggggtg gggatcgtgg agcgggcgct gccgctcacc gggggcggcg
     6661 cactgccgca cgggcatgtg gggccgggcc tgtatgtgga gcagcagcct gccgtcgagc
     6721 cgacgtcact gacgctggac gtgcggacgg tggcgtacga ggtgcgcgcc gatcacgatc
     6781 tgctcgccct gcccgggctg ttcgggctca cggcggcagc ggatgcccgg cacggccact
     6841 tctccggcat cagcgactac ccactcgcga tcggccaggc ccgccagtcg gcgctggcgc
     6901 agttcggtcc gctggggttc cgggcggcgg cggtgacggc cgtgatgccg gaggcgggcg
     6961 gcctgccgcc gcagtaccgc tacgagtcca cggtcgtgcg ggtcgtcttc gaccgtccct
     7021 tcggctttct cgccgtggac cgtgagtccc ggctggtgct ggtggcgggc tgggtgacgg
     7081 atccggcgcc ggagccggtc atgagcttcc cgggcgctgt tcctccagga ctctgacaca
     7141 gcgggcgatc agcccggtca gggcgtcccg ctccgcctcg gtgaactccg cggcgagggc
     7201 tcgctcgacg cgtacggcgg aggtgtcggc cgcggtgagg acggcgcggc cctcgtcggt
     7261 gaggcgggtc tccaggacgt tcttgtgcca ctcgtgcggg ctgcgggtga tcagatcgcg
     7321 gtcctggagg ttcttcagga ccgtgttcat ggtcggcggg gtgaccccgc acagccgggc
     7381 gagggcggcc gcggagatgc ccgggttgtc gtcgaggtgg agcagcgcgg cgtactgggc
     7441 gacggtcagg cccgcgggct tcaggaccgc cgccttggtc gcgttgaggg cctgctcggc
     7501 ccgcttgagg tgggagccga ggcgctcgga cgcgggcatg gaggtcaccg gaccacatta
     7561 atgccttggc caggatgaat gccctgatga tgatcaggat actctcgatg attaatacac
     7621 tggtgatcgt tagagttcta atatagcttt gcatccgtca tgcagtgagt agccgaaccg
     7681 agaggcgcct gtcgtgtccc gttcgatcca ccgccgtacc ttcctgtccg gcgccgccgc
     7741 cgcggccgtc gccgtcgccg cgccccgggc gaccgcggcc accggccccc gcatctcgac
     7801 cgccttcacc ctccccggcg accgcgccta ccccgagggc atagccctcg acccccgcac
     7861 gggcgacgcc tacgtcggct cctacacgac cggcgcgatc taccgcgccg ccgccggcag
     7921 ccgcaccgcc gaggtcttcc tgccggccgg cacggacggc cgtacgacgg ccaacggcct
     7981 gaaggccgac cgggcgggcc gcctctgggt catcgaccac accaccgggg tcgacgtgta
     8041 cgacctgagc gaccgctccc tgctggcccg cttcgaggta ccggcaggcg acccgcactt
     8101 cctgaacgac ctcgtgatca ccgcggacgg cacggcgtac gtcaccgaca gcgtgcgccc
     8161 ggtggtctac cggatcaccc cggccgacct ggcccgcgcg cacggcggcc gggcgccact
     8221 gaccgcacgg tacgacctga gcggggccgt cccgtcgcac gggccggacg cctacaccct
     8281 gaacggcatc gccgccgacg ccaccggacg ccggctgttc gtggtcgaca tgaccggcgg
     8341 cggcctgtac cgggtcgacg tgaccgacgg ttcgatactc caagtcaccc tgcacggcgg
     8401 cgacttggtg cacggtgacg gcctggacct gtcccaccgc accctgtggg ccgcccacaa
     8461 caagagcaac accctgaccc gctggcacct ctcccccgac ggcaccgagg cccgtcttct
     8521 ccgtaccctg accgaccccg ccctccagat ccccaccacc ctggcccaca ccccccgcgg
     8581 cctcctcgtc gtccgctccc agttcgacaa gggcggcccg atgggctcgg gcacaccgac
     8641 gacaccgttc acggtggcgc gggtgacggg gatgtgaccg gtcggccggg gcgatgttcg
     8701 ccggtggcct ccagctggac cggcccgcca tgacgccctc gtcccgcttc accgggcttt
     8761 cacgtcaagc ccgctgatct gcgtgatccc cggtcgcgcc accgggtgac cagccacagg
     8821 acgttgacgc cgcccagggt gatcaggact gccgccgagt cggtgttgcc cgcgaggccg
     8881 tgccccggcc ccagtccccg tgccgcgcgg atcagcaggg tgacgtcgac agggagtgtg
     8941 accgcggcca tgaacgtcag gcaggccacc gtgccggcca caaggacggc gctgtagagg
     9001 cggacggccc ggcgctcgtg cgggggcagc cgggagctcg ggtcgtcggt cccggtggtc
     9061 cggccggggc gcagcgatcg caccgcccgc cggaacacgt accgcacgta ggcgagaccg
     9121 tcgccgtaca ggttccggca accggtgacg tcctggacga cgaagtacag gtccgtacgc
     9181 atgaacacca tgagctggaa gggcaacggc atcagggcca gcagcagggc cgcggacagc
     9241 agccggcgga ccgtcgtacc ggggctcgcc agggcgaggg tcaggaccag cgacgaggcg
     9301 acggacaggt tcagggcgat gccggccagg taggccgtca gccggtggcg gcggggcgcg
     9361 agctcgatgc cgctgatgtc cgtctgcatg acgaggaact gcagccgggt gcccagccgc
     9421 atcttccccg gcacgcccgc ggcgcgggcg gtgaccaggt gcgccagctc atgagccagc
     9481 accagcgccc acccggctgc cgccccggtg agcaggacca ggctgccgtg cgggctccac
     9541 agcaggtcgc gatagcccgg cagcaggccg ggacggcgga tcaggacgac gacggcagcc
     9601 gccagcagcg ctccggcgaa cacgggaagc accgggtgca gggcgaaccg gacatggtgg
     9661 gggcgcagcc atggcagcga cgcgcgcggc ggttcggcgt ccggaatcgg acactccccg
     9721 atccgtgcca cgaaccccag agcggccagg tccctgacga actccgtgat ctcgaactcc
     9781 tcgccggtct cgtcacgcag cgtctccgcc gtgcgggcca cgctcagtcc ctcgcccagg
     9841 agttccaccg cccgggcccc ggccgccggc atggcgacga aggtccgggt ggtgatgcgg
     9901 cccacgatcc actcgtcccg ttcacgctgc accgccaggt cgtgcagcag gacgcgggcc
     9961 gacggctcga ttcggggaag gccctccgcc gcggtgtccg tcacgagagg tcccccggtc
    10021 cccggtgcgc ggccggttcc ggcccggccg gttccgctcg gcaggcgggg cagtcggggc
    10081 gtcggtccga gcgctgctcg atcgcgtctc cgggcaccat gagattgagg ccgaaccggt
    10141 gcccggggcc gaccgggggg acaccgcaca gcagcgtgat ggcggcatgg gccagcagac
    10201 cgccggacag gcccgcggtc acggcgttga ccggattcca cggcatgcgg ggcgaggcga
    10261 catcctcgtc ctggccgggc gcgagccgca gatcgcgccg ctcggcctcc gcgatgcgca
    10321 gacactccca gcacgcgccc cggcccggcg tgaagacccc gacactcacc agtggaccgc
    10381 ggtaaccggc ttcggcccac gacgtgccgg aggccaggca gacccggttg gtccagctgc
    10441 ggatggccgc ggggcggtcg gcggccagca gcagtacgtc gtaccccgac ccgccgccgg
    10501 agctgtcggg ggcgccggtc agcaggtctt cgaggtccgc cggcccgcgt acctcgcggc
    10561 gctcgccggt gaccgtcgtg tccgagttca gggcgcgcaa cgccgtcagc gccgcgtcga
    10621 tcttgggcgt accgaggtcg cgctcgctga agagggtctg ccggttgagg ttggacagct
    10681 cgacgacatc cgggtcgacg cagtgcagcc gccccactcc ggaggccgcc aggtcccgtg
    10741 cggcggcgcc gccggtaccg ccgacgccga tcaacaggac ccgggcacgg cgcagccgca
    10801 cctgcggctc ccaggaactc tccctcggcc ggagatccat ccagcgcagc agggtcatgc
    10861 ccctgctgta ccgctcccgt tcccgctcgg acagctccgc cggcggggcg gcaccggcgt
    10921 cctccacgaa cccggccatg gtcagatccg tcatcgcctg cacgatgtcc ggggccggtg
    10981 gccgtaatcc cggatggcgg cgggacacct cggcgacgat ctccccggcg ttccgcgtgc
    11041 cgtccatggc ctcgaccagc gtccacaccc agccgtcggg atccttgacc tcggcaccga
    11101 tgccgtggac gacgctcccg atcctcacgt ggccgtcaac ggttcggtag gcccggtgct
    11161 ccggcttgat ccgggggcgc cgcatcgcgg gcaccgtcat catcgcgcca atctcctcag
    11221 ccccaactcc tccgactgca acggacattg acaagcgtca cccggcgagc gaaccctgac
    11281 aagagcacat caacccactg cacgccacgg ccaccaccgg gaggacacgg catgccgaac
    11341 aagatcgaga tccgtccgct ggacaagaag gagaccacca gcgacagcgg cggtaacggc
    11401 ggcgcctgac cagacgcgga tgatgaaccg gtaccccacg gtcgcggaag tcaccgagtc
    11461 ggcacggcag ttggtctccc ggttccccgg agccggccgc ctgcgccgga tcgggacgtc
    11521 ccgggcgggc cgcccggtcc tgatgctgtc cgtgggacac gggccgcgtc acatcctggt
    11581 ggtcgcccgg ccgcaccccg acgagccggt cggcgccgcg accgcgctcg cgctggcgga
    11641 gcgagtggca cgcggcgacc ggctgtccgc ggcgaccgac cccgccatcg tcacctggga
    11701 catcattctg tgcctggacc cggacggcgc cgccctgagc catggaatcg aagaggcgac
    11761 ggccgggccc ggccacaccc tggacaccta ctaccgcacc gcctaccgcc cggtcgcggc
    11821 ggaacagccg gagtgggcac cgatcgaatc gcagcaactc ccggagagcc aggcgctgtt
    11881 ccgtgtgatc gacgaactcc gtccgtttct ccagtgctcc ctgcacggcg tcgaagcggg
    11941 cggcagctgg gtccaggtga cccgcgacct ccccgagctc gctgtacctt tccaggcgtc
    12001 cgccacggag ctcggcattc cggtccagca cggcacgttc gacgccctgt actgggaaaa
    12061 ccccagcccc ggggtctacg tcctgccacc gccggacagc accgaccgcc tggcggccgg
    12121 gtccgagaac atcgggttgt ccacttggtg cgcacctcag cggtacggcg gcgtcacggc
    12181 gatcatcgaa gtgcccatgt gggcgaccga cctcgccgac gatctgtccc cgcacccgga
    12241 agccgctcac gtactgcgcg aactggccgg gctggtacgg gagcgcggac ggcaggtgac
    12301 cgccgtcctc gacaaggcac gcgcattcct gccaccggcc caggacagcc cgcccagacg
    12361 cgtgctggag tggatggccg acggtctgta cgacctggtc gccgactcct gggaaccgct
    12421 cgcccggcag gcggccgccg cgtcacaccc cgacgatccg caccggttga cgacggccca
    12481 ggtctgcgcc ctggacatcg tggcccgccg ccaaccgctg cgcgccgcgg gtcttctgct
    12541 acggctgctg aagacgacgg acgacgccgc cgcccccggt ctgcaccgcg acctggacga
    12601 actcttcacc gcgtggtgca cggacttcga gacggccctg cggctgcgct gggtgccggt
    12661 gcaccaccag gcggaacacc aggcacgcac ggtcgtggca gccgccgaga ccgcgctgac
    12721 ggccctgcag tgaacccgac accgacccgg gaccgctacc gcgccccggc gacgatctcg
    12781 tggcccgcgc ctcgtcgaat cgctacggtt gagccatgac cgcactgccc gactggatgc
    12841 gcccgccgcg cgaggaaggc tggttcgcgg aggacctgga ccgccttccc gaggcacccc
    12901 gccacaccga gctgatcgac ggagcgcttg tcttcgtgat gtcgccgcag aggtggtggc
    12961 acggccacct cgtcaccatg ctcaccgtcg ctctcatgga gcaggcgccc ggcgatgtca
    13021 gggtcggccg cgagatgacc ataaagctcg acgagcgaaa ccggcccgag ccggatctgc
    13081 tgctgacgac cgccgactac gacggagacc gcacctggtt cgcgccggac gaggtgcgac
    13141 tcgtcatcga ggtcgtctca cccgagtccg cgcaccggga ccgcacggtc aagctccgca
    13201 agtacgcgga ggcaggcatc gcgcactact ggtgcatcga ggacgagaac ggcgcccccg
    13261 tcgtccatgt ctatgaactc gacgaaccaa cgggagccta cgcacccgcc ggcatcttcc
    13321 gaggcacctt ggagcgcccg gttccgttcc agatcaacct ggacctcgac aagctcaccc
    13381 caccgcgggg caactgaagt cagcaatcgc ctagcgctca gcaacgcggc gatcacacgt
    13441 tgaaccggaa cgcccacggc aacgctgcga cctgcggaaa cgcgcctttc cacgatccca
    13501 tccagcacag gtccagcacg gtggcggttt acccagcacc tccgagcgat cgtgaagccg
    13561 ttgtgtacac atgagacact cggtacactt gggtgtatga cgcagccact gcccacagag
    13621 tccatccgcg atgtccgggc acacctggcc gaggtcgtgg aacgagccga ccgtgacgac
    13681 gtacccacgg tgatcacgcg ccgaggcaag gaggtggctg ccgtggtgtc catcgacatg
    13741 ctccggaaat accaggagtg ggaagagcgc gagatcaacc ggatcatcga cgagcgcatg
    13801 gccaatccgg cgcccggcat cccgatcgag gacatcatga gggagacgct ggcgcgcagt
    13861 gagtgagtac cgcaccgcct tccggcccga ggctcaggcc gaactccgca aggtcccgcg
    13921 agacatgacc ctccgcattc tggccaagtt gaccgagctg gagagtgacc ctctggggtt
    13981 caacaccacc gccctcgtct cccaacccga ccgccgccgc ctatgcgtgg gcgactaccg
    14041 cgtgatctac acgatcgaca acggcgagct ggtggtgtgg gtcgtgcacg tcgggcatcg
    14101 ctccactgtg tacgacacct gagtacgcct gacgtcgggt cagaacatcc agcaccgatc
    14161 cagcacggga ttcgcgacaa agtacgagaa ggctcgggac cgccaacact acacaacagc
    14221 gtcagcaaga gatcgaggtt cgagggactt ctccgcgacg cccttgcagc ctgatcgcgc
    14281 cccaaatccc ttgccttgcc tgctactcgc cactcacagc ggccaggctg tcagcaagtg
    14341 gccggggccg taggcggcgt cgagccccgg acagtcgact ccgctgcgcg agaccgccac
    14401 gacgggaaca ggttcgtcgg tgagggcggc ccggtgtcgg tggagggcgg ccaggtcgtg
    14461 ccggtcgaag ggcgactgct ccagccactt gatggagccc acgaagagca gctccttggc
    14521 aatgggggcg cggtccgccc cgacgatgtc gatttcgacg tcgttggtgc gggtccagta
    14581 gccgcccacc gcgggggctg cgggcagttg gccgtcgggc agtatccggg caagcgcctc
    14641 gcggatgagc ggctcgatcg cccggccgcg ccagctggtc cagttctccc ggatgcgcgc
    14701 caaggtcaga tcgccccgcc cccgctcgat ctcttccatg gacgggccga gcaagtgcag
    14761 ccaaaaccgc aggtagggat ctgtcacccg gtaacggcga tccttcgacg gacgcagcga
    14821 tacaggcagc tccccagcga cgatccgttt gtccgtaagc agctccagag ctcgctgcag
    14881 cggcgtggcc ccgatcccgc cggctgcacg ggcgatgttg gtgaaggtcc gctcgccact
    14941 accgatagcc gccagcaccg tacgcgcctg ggcctgcggg gggaattcgg cagccagcga
    15001 gcgctcggcc gacaccagca gggccgagac cggatcactc aacgcctcgc caaggaagtc
    15061 ccacaaccct gcgccgcgcg gccactcagc gcagatcagc ggcagcccgc cagtgaccag
    15121 cgcagcgtcg aaagcttccg ccggatccag cccaagcatc tgtcccacct ctgcggggtt
    15181 gagtggtccc agcaccatct cccggccgcg ctgatggaag ggtcgcccgt agctgttcag
    15241 tgcctccatc atcgacagat cggagccgat gaggaccagc agcactggct tggtttccag
    15301 cacccgatcc caggcccgct gcagcatccc ctcaaaggcg ccatcggtat ccatcaggta
    15361 cggcacttca tcgatgacca gcacgctcgc ccggtcagcg ggcagcgccg cagccagcac
    15421 gtcgaacgcg gcatcccaac tctccggccg cgcggcggcc accagccccg ccaacggcag
    15481 cgtcgatgcc tgggcgtccc gggcgagtcg cgcaagatca tccctagggg acgcgccggt
    15541 cgccgcgtag aacaagaacg gggccccgga gcgctccgca aaccgctcga ccagtcgcga
    15601 cttgcccacg cgtcgccgcc cgcgcaacat cacgcaccga ccgggccgct ccccgccaac
    15661 ccctgcagcg accttctgca gctctcgctc caacgtcgcc agttcctgcc gacggcctac
    15721 aaagtccacc acgcctaccc acctccgccc atgatactaa cttgaatgtt agcaacattg
    15781 acgttagtgc gggaccttta ccggtgtcga tcacggtcac gagtcgtgga cccgacgtcc
    15841 ctccagccgc gccgggcgat gcgcgcaccg aggtcgtagc ggctgagagc gtcggggccg
    15901 gcgaggtgga agaggccggc cccgtccgat cgcgtgagtt accacaaggc ggcggccagg
    15961 tcctcgacgt gcacggggca gcgcacgtcg tcggtgaaga gaacacctag ccatgcggac
    16021 aggtcctcga tgaggtggac gagggccgtc gccacaccgc tgtagcggtt gtcgttgtaa
    16081 cgggaacgag caaggggccg acccgaaaac gagacgaccc ctcctgactt gcatgtttgc
    16141 cagggcggca aagtggtgtt aattcacccg ctcacacatt gaaccggaac tccaccacgt
    16201 ccccgtcctg catgacatag tccttgccct ccatgcgggc cttgcccttg gctcgggcct
    16261 cggggaccga gccggttgcg agcaggtcgg tgaaggagat gacctcggcc ttgatgaagc
    16321 ccttctggaa gtcggtgtgg atcacgccgg ccgcctcggg ggctgtggcg cccttcttga
    16381 tcgtccaggc gcgggactcc ttggggccgg ccgtgaggta ggtctgcagg ccgagggtgg
    16441 cgaagccgac gcgggcgagg gtggcgaggc cgggctcgtc ctggccgacg gactggagga
    16501 gttcgagggc ctcctcctcg tccagttcgg ctaggtccgc ctccagcttg gcgttgagga
    16561 agatcgcctc ggcgggggcg accagggcgc gctgctcgtc cttgaagtcc tcgtcgatca
    16621 gttcgtcctc gtcgacgttg aagacgtaga ggaaaggctt cgtcgtgagc aggtgcaggt
    16681 cgtggaggag ttcgttgcgc tcggtgccct ggacgatgcc gtgcgcgaag agcgtgtcgc
    16741 ccttctccag gatctccttg gcctcctcga ccgccttgac cttgggggcg atgtccttct
    16801 tgatgcgcga ctccttctgg aggcgcggga ggaccttttc gatcgtctgg aggtccgcca
    16861 ggatcagctc ggtgttgatc gtctcgatgt cgtccttcgg cgagaccttg ccgtcgacgt
    16921 ggacgacgtt ctcgtccttg aaggcgcgga tgacctggca gatcgcgtcg gactcacgga
    16981 tgttcgcgag gaacttgttg ccgaggccct cgccctcgga ggcgccgcgc acgatgccgg
    17041 cgatgtcgac gaagtcgacc gtggccggga ggatgcgctc cgagccgaag atcgacgcca
    17101 actgcgcgag gcgggcgtcg gggacgccga ccacgccgac gttcggctcg atcgtggcga
    17161 acgggtagtt ggccgccagc acgtcgttct tggtcagggc gttgaaaagg gtcgacttgc
    17221 cgacattggg caggccgacg attccgatcg tgagcgacac gttgcgactt cccgtagatg
    17281 agtgggccag ggggtgccag gggccagaga ccgacactgg ccgatccccc agtttacggc
    17341 gtccacgccc accggctcgc gggagcttcg aacgcccggc caggctctgc gcaccggcgt
    17401 gtctgatggg tgattcggca cataaacaga cctaagttgg tccagtggag caacacggat
    17461 cgcgaccctc ggacgacgga ccgcgaagtg gcacgccgca gcccgcgcac ctgccctcgc
    17521 aggcccggcg ccggtcgggc ggggagggca gatcgggagc gtgggcgcag cggaaggagc
    17581 gcggcgcacg gatggcgcgg gcggcccggg cggtgcgggg accgcgtctg ccgaatcccc
    17641 ggctcaccgg gcgcggcacc ggactgttct gtgtcgtcgc gatgttcctg ctcggctgtc
    17701 tggacgcgct gctgttcgac gggtacatgc ccgtgtacgg cgtgctgttt ctcccggtgt
    17761 gcgtgctgac cgcgctgtgg gcacgggcgg gggacgtgct gaccgccccg gtgatcgtac
    17821 cgatcgcgtt cgccgtgggg ctgatccccg ccgccgacgg aaacgggggg ctgctcggcc
    17881 ggctgatggg gctgttcacc gggctcgcca cccaggccgg ctggctgtac accgggacgc
    17941 tcttcgccgg agtgatcgtg ctcgtacgcc gggtgcggtg ggtacggggg cgccggcgac
    18001 gaacctgagc cggcgcgtca cggccacgct gtcctacgcc gcctgggctg cccgggccct
    18061 acgtcagctg ggccgctctc atcgccgctc ccacgatccc cgcgttgttc tgcagctggg
    18121 ccgggacgat ctcggccttg atgccgtcga gcaagtgcag gaacttgtcg gccttgcggc
    18181 tgaccccgcc gccgatgatg aacagctccg gcgagaacag catctccaca tgcgccaggt
    18241 acttctggac gcgctgtgcc cagcgctccc agctcagctc gtggtcttcc ttggccttgc
    18301 tggaggcccg cttctcggcg tcgtggccgc ccagctccag gtggcccagt tccgtgttcg
    18361 ggacgagggc gccgtccacg aagacggcgc tgccgatgcc ggtgccgaag gtgagcagga
    18421 tgaccgtgcc cttacggtcc cggccggcgc cgaactgcat ctcggcgacg cccgccgcgt
    18481 ccgcgtcgtt gagcacgacc accggcaggc cgcccagtct gccggtgaac aacgcgcgcg
    18541 cgtccgtgtc gatccagctc ttgtcgacgt tcgccgccgt acggatcatg gcgccgcccg
    18601 tgaccacccc ggggaaggtc agaccgaccg ggccggtcca gccgaagtgg tccacgacct
    18661 gcttcacccc gtcggccacg ccgtccggtg tcgccgggtg cggggtgagc accttgaggc
    18721 gctcctgagc caggtcgccc ttgtccaggt ccacaggggc gcccttgatc ccggatccgc
    18781 cgatgtccac gccgaagatc tgcatggcac cacgttacga cgcgggactg acagtcactc
    18841 cgcggaagga ccggtgccgc cgcgctcggc gaccagggtc gtcgcctcct cgcgcaggtc
    18901 gcggcgcagc tccttgggca gcgagaaggt gatggactcc tcggccgcct tgacgatctc
    18961 cacgtcgccg tagccgcgct cggagagcca ctccagcacc tgctcgacca ggacctccgg
    19021 gacggacgcg ccggaggtga cgccgacggt cgtcacgccc tccagccagg cctcgtcgat
    19081 ctcgtcggcg aagtcgacca ggtaggcctc gcgggagccg gcgagcttgg cgacctcgac
    19141 gagccgcttg gagttggagg agttgcgcga gccgacgacg atgaccagct cggcctcggc
    19201 gcccatctgc ttcacggcga gctggcggtt ctgcgtggcg tagcagatgt cgtcgctggg
    19261 cggggagacg agacccggga acttggtctt cagggcgtcg acggtctcca tggtctcgtc
    19321 cacggagagg gtggtctggg acagccagac gaccttggac gggtcgcgga cctcgacctt
    19381 ggcgacgtcc tcgggaccgt cgacgagctg gatgtggtcg ggggcctcgc cggaggtgcc
    19441 gatgacctcc tcgtggccct cgtggccgat caggaggatg tcgtagtcct ccttggcgta
    19501 gcggacggct tccttgtgga ccttggtgac cagggggcag gtggcgtcga tggtggcgag
    19561 gcggccctgc ctggcctcct cgtgcacgac cggggcgacg ccgtgggccg agaacatgac
    19621 gatgttgccc ggcggcacct cctccgtccg ttcgacgaag acggcaccct tcttctccag
    19681 ggtctgcacg acgtacttgt tgtggacgat ctcgtgccgg acgtagatcg gggccccgta
    19741 ctgttcgagg gccttctcga cggcgatgac ggcgcggtcc acaccggcgc agtagccccg
    19801 gggggcggcg agcaggacac ggcggccagg cgaagcggtc atgcgtccca tcgtaaggcc
    19861 gcgttcggcg gcgtcgagat cgcgtccccg gcgccgtgcg gggaacactg ggtgccatgt
    19921 ccgacacgga aaccacggcc tccccgacgg atgagcacca cgggctgcgg cggagcctcg
    19981 gcttccggga tctcgtggtc tacggacttc tcttcatcgc ccccatggcg ccggtcggcg
    20041 tcttcggcac gctggacgcc aggtcgcacg gtgcagtggc gctggtgtac gtggtggcga
    20101 cggtcgccat gggattcacc gcgttcagct atgcgcagat ggtgcgggtg gtgccgcagg
    20161 cggggtcggt gttcgcctac gcgcgcgtgg ggctcgggaa ggaggccggg ttcgtcgcgg
    20221 gctggatggc gatgctggac tatgtcctca tcccggcggt ggcctatctc ttctccggga
    20281 tcgcgatgaa cgcgctggtc ccgcaggtgt cccggtgggt gtggaccgcg ctggccgtcg
    20341 tggtcacgac actgctgaac ctgtggggcg tacggacggc cgcgatcgtg ggtttcctcg
    20401 tcctggccat ggagatcgtc gttttgctgg tgttcgtggt ggcggcgctc gtggtgctgg
    20461 cgcgggacgg ggcggcgcgg gggccgtgga cgccgttgtc cggtgacggc acacagggtc
    20521 ccttcgcgct ctcggcggtg ctcggcgcgg tgtcggtggc ggtgctgtcg tatctgggct
    20581 tcgacgcgat cgcgacgttc gccgaggagg tcaccggggc gtcggcgaag gtggcgcggg
    20641 cgctgctgtt ctgtctggcg ctggcggggg tgctgttcgt ggcgcagacg tatctggtgg
    20701 cgctgctgga gccgacgacg tccgcgcggc tggccgccgc tcccggcaag cagggctcgg
    20761 ccttctacga cgccgtggac gtctccgtcg gcggctggct gcacgatctg gtggccgtga
    20821 gcaaggccat cggggcggcg ttcgcggcgc tggccgggca ggcggcggcg gggcggctgc
    20881 tgttcgcgat gggccgggag cggcggctgc cccgggccct gtcccggacg gacgccggtg
    20941 tgccgcgggt cgctctgctg tgctcggcgg tgatcacgct ggtcgctgcg gggtgggcgg
    21001 cgcggcggga cgacggtctg gacaggctcg tctcggtggt cgacgtgggc gcgctgacgg
    21061 cgttcacgct gctgcacgcg agcgtggtgg ggtatttcgc ggtacggcgg cgggaggggc
    21121 ggctcagctg gtggcggcat gtgctggtgc cgggggtggg agcggcgatc acggtggcgg
    21181 tgatcgtgga ggcgagcggg
//
