LOCUS       NZ_CM002285            21176 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3123652
            Orig. end                         :: 3144828
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="21"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21176
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11176](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11176)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(500..1258)
                     /locus_tag="M878_RS63155"
                     /old_locus_tag="M878_14235"
     CDS             complement(500..1258)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657871.1"
                     /locus_tag="M878_RS63155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14235"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_023546841.1"
                     /transl_table=11
                     /translation="MTMSTGTDWAAWQGSWDRQQEWYMPDREERFRIMLDMVEALAGTA
                     PRVLDLACGTGSITDRLLKRFPRATSTGVDLDPALLAIARGTFECDERVTLVTADLKEP
                     DWPAKLPYDSYDCVLTATALHWLHSEPLAALYGQVAELVRDGGVFMNADHMIDDSTPRI
                     NAAERAQRHARMDQAKRDGALDWADWWQVAAKDPVLAGPTARRYEIYGEHADGDMPSPG
                     WHARVLREKGFGEARPVWCSPSDTLLLAVK"
     gene            1359..1988
                     /locus_tag="M878_RS63160"
                     /old_locus_tag="M878_14240"
     CDS             1359..1988
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136637.1"
                     /locus_tag="M878_RS63160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14240"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_023546842.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNSEEPARGKDSLTSVEAVRDLFGANSSAARR
                     TTDADVTRFRSVRARLRAVFEAADQGDETLAVDLLNSLLLEFPVSPQISGHDFRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSGSNGLAAENAQRTSASGER"
     gene            complement(1892..2326)
                     /gene="sodX"
                     /locus_tag="M878_RS63165"
                     /old_locus_tag="M878_14245"
     CDS             complement(1892..2326)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="M878_RS63165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14245"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_037730607.1"
                     /transl_table=11
                     /translation="MPELSQETERGRAVAPFGVAEVTGPSMVPALQHGDRLLVQYGASV
                     RPGDVVVLRHPFQQDLLVVKRAVERRDGGWWVLGDNPYAGGDSTDYGVVPDELVLGKAR
                     FRYRPLPAGQRSPLALVRWAFSAARPLLPDRSASRRLRAR"
     gene            2472..2867
                     /gene="sodN"
                     /locus_tag="M878_RS63170"
                     /old_locus_tag="M878_14250"
     CDS             2472..2867
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="M878_RS63170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14250"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_023546844.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDALKALSAAKA
                     STDPATGQKALDYIAQIDKIFWETKKA"
     gene            complement(2950..3768)
                     /locus_tag="M878_RS63175"
                     /old_locus_tag="M878_14255"
     CDS             complement(2950..3768)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889358.1"
                     /locus_tag="M878_RS63175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14255"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_023546845.1"
                     /transl_table=11
                     /translation="MTELSAAHDAAVTDRGRLAGSAYSSDRDLAARQSLYQWQTPRYDL
                     PGIVAEQLRGVRGRVVDVGCGNGKFIQRLREDRPDLALLGLDIAPGILAGVPGPVAVAD
                     ATRLPLATESVDAALALHMLYHVPDIPQAVRELSRVVAREGLVIVSTNSDRDKAELDDL
                     WQRAAGDVLGTGRGPARISLSARFCLEKAPSFLGEEFGRVEAIGLPGTIRVQDPGPVIA
                     HMASYRAWADQHDVPFDATIERARTILLGHIAQHGAFEVTCLGGILVCRR"
     gene            complement(4168..4701)
                     /locus_tag="M878_RS63185"
                     /old_locus_tag="M878_14265"
     CDS             complement(4168..4701)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS63185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_14265"
                     /product="hypothetical protein"
                     /protein_id="WP_023546847.1"
                     /transl_table=11
                     /translation="MFGRRGVAVALGSVMLAGSSLVWAPIGRATADEEGSVGCVGHSES
                     RYDPPLKLLAGPTHVHADITYTCGAHGRTVPATGSFNSEAPAASCVAVSGGSGTETIRY
                     ADGGRSLIAYDSATTLRVTGVLVVIQRGRVVEGRGQGHPVRRTITGLPQELPTECLTSG
                     LQGGSNEVQLEIEP"
     gene            4944..5459
                     /locus_tag="M878_RS63190"
                     /old_locus_tag="M878_14270"
     CDS             4944..5459
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004943375.1"
                     /locus_tag="M878_RS63190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14270"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_031224883.1"
                     /transl_table=11
                     /translation="MGRTTVAAATVARGRIFAMMDADGDGVISAHDYLSRVDRAVQATG
                     RSEDDPLVVAARGQAHKAWGAMDANGDGKLTFEEYDAWVGADKFDNICRFALGSLFDLA
                     DADGDGALDKTEFTMLRTALNNAPGNAASAFNALDTDGDGLVVRDEYLASIRSYVIGDA
                     SPMGEALY"
     gene            complement(5508..5732)
                     /locus_tag="M878_RS63195"
                     /old_locus_tag="M878_14275"
     CDS             complement(5508..5732)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123531.1"
                     /locus_tag="M878_RS63195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14275"
                     /product="hypothetical protein"
                     /protein_id="WP_023546849.1"
                     /transl_table=11
                     /translation="MHVDWSALGKVAAVSLGVTVAVVVVFTFGVLGLSRAEADRSGSAT
                     AGRAQAALCFLACAAVVAYGICLIVPQFH"
     gene            complement(5750..6904)
                     /locus_tag="M878_RS63200"
                     /old_locus_tag="M878_14280"
     CDS             complement(5750..6904)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058926.1"
                     /locus_tag="M878_RS63200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14280"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_023546850.1"
                     /transl_table=11
                     /translation="MDHITFLVAVVIVTALAFDFTNGFHDTANAMATSIATGALKPRTA
                     VLVSGVLNIVGAFLSTEVARTISGGIVDDTLVSPAMIFAGLVGAILWNLVTWLAGLPSS
                     SSHALFGGLIGAVWVGAGSHGVHFDKVVEKVLIPAVASPVVAGVAALVATYLAYRLSAR
                     ARRDSVTKGFRLGQIASASLVSLAHGTNDAQKTMGVITLTLISAGALGHEAGPPVWVIG
                     AAGLAIGLGTYLGGWRIIRTMGKGLAEIQSPQGFAAETASTTVILTSAHLGFALSTTQV
                     ASGSILGAGLGRRLAEVRWGVAGRMVLAWLITLPSAALVGGLAASVVKHGGNVGTAVIA
                     LVALALAAVIVAASRRNPVRADNVNDHHDVTLRTPAPPHVGAAA"
     gene            7044..7442
                     /locus_tag="M878_RS63205"
                     /old_locus_tag="M878_14285"
     CDS             7044..7442
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925786.1"
                     /locus_tag="M878_RS63205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14285"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_031224885.1"
                     /transl_table=11
                     /translation="MTLDDLRRLRRVRDRMDREYAEPLDMTELARGAHMSPGHFQRSFR
                     KAFGETPYSYLMTRRIERAKALLRRGDLTVTEVCLAVGCTSLGSFSSRFTELVGETPSA
                     YRARDHEESAVIPSCVARTFTRPRRRPY"
     gene            7553..7969
                     /locus_tag="M878_RS63210"
                     /old_locus_tag="M878_14290"
     CDS             7553..7969
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072193.1"
                     /locus_tag="M878_RS63210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14290"
                     /product="VOC family protein"
                     /protein_id="WP_023546852.1"
                     /transl_table=11
                     /translation="MDVKLKQCFIAVDDHDKALAFYRDVLGLEVRNDVGFEGMRWVTLG
                     SPLQPDVEIVLEPPGANPDASPADRQAMAELLAKGMLRGVIFTTEDCDALYERVRESGA
                     DVLQEPTDQPYGVRDCAFRDPAGNQLRFLQRPAE"
     misc_feature    complement(8038..8051)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            8041..8790
                     /locus_tag="M878_RS63215"
                     /old_locus_tag="M878_14295"
     CDS             8041..8790
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384638.1"
                     /locus_tag="M878_RS63215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14295"
                     /product="VOC family protein"
                     /protein_id="WP_023546853.1"
                     /transl_table=11
                     /translation="MIIRWTYAFVDRPAGRLREARAFWTAVTGTHASEPRGEQGEFLTL
                     LPEEAAGTDACVKLQGVAEGDGGAHLDLCAEDVRELTANARELGAELVADHGDWVVLRS
                     PAGQSFCAVPWHGETVRPPVVAGSRLDQVCLDIPPSRHAAESDFWATLTGWERLKGSRP
                     EFEVLKPPAGLPVRILLQRLDDERPASAHPDLACADIAAVRARHEEYGAAPVHHGPHWT
                     VMRDPAGGVYCLTGRDPETGGLPAAGR"
     gene            complement(8852..9184)
                     /locus_tag="M878_RS63220"
                     /old_locus_tag="M878_14300"
     CDS             complement(8852..9184)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674925.1"
                     /locus_tag="M878_RS63220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14300"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_023546854.1"
                     /transl_table=11
                     /translation="MPKLPRIFHITERSLWEAARERGAYEVSTRGRTLQEEGFIHFSTR
                     EQLPRIAAFLYGDYDGPDELVVLVVDPALVAAPVKYEAMEPGGEEFPHVYGPLPADAVV
                     EVESWG"
     gene            complement(9226..9810)
                     /locus_tag="M878_RS63225"
                     /old_locus_tag="M878_14305"
     CDS             complement(9226..9810)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767199.1"
                     /locus_tag="M878_RS63225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14305"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_023546855.1"
                     /transl_table=11
                     /translation="MRKLSYFIACSLDGFIGDEQGDASAMFRFMNEEYLDFLKTEFPET
                     MATHGRRPLGLDHLENKRFDTVIQGRGSYELALKEGITSPYAHLREYVASRSLAVSPDP
                     HVEIIADDLLGRVHALKAEEGGLDIYLCGGARLAGELLDEIDELVIKTYPLVYGTGMPM
                     FGTGLDIKEFTLDGVRTFTNGVLVRTYTRQR"
     gene            complement(10001..11176)
                     /locus_tag="M878_RS63230"
                     /old_locus_tag="M878_14310"
     CDS             complement(10001..11176)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674923.1"
                     /locus_tag="M878_RS63230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14310"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_023546856.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-58, bitscore:
                     196.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEFMTETEQRSPAVPHPGTAGERRGRTGDADAGQAGGHPERHPE
                     ARLEGQEAVALLERTRTLVDPELRAALESLPGSMRRIALYHFGWQHADGTPARGNAGKA
                     IRPALVLAAATALGGPAGRTAAVRAAVAVELVHNFTLLHDDVMDRDASRRHRPTAWTVF
                     GTADAILAGDALQALALRMLAEDPHPASGPAAARLADCVVELCAGQHTDVDMERRAPGE
                     VTLDEVLAMAEAKTGALLGCACALGALYAGADGEDVAALDGFGRQAGLAFQLIDDVIGI
                     WGDPRRTGKPAGADLAARKKSLPVVAALSSGTEAAAELAELYDEPYVSGDAEGIVRTAL
                     AVERAGGRDWAQAEAADRMARAVQELSRAVPAPEAAGGLLALAEFVTRRSG"
     gene            complement(11289..12695)
                     /locus_tag="M878_RS63235"
                     /old_locus_tag="M878_14315"
     CDS             complement(11289..12695)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="M878_RS63235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14315"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_023546857.1"
                     /transl_table=11
                     /translation="MSVGEEVRTDQGKPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RTLPWVDVHGGTYRVNRRLAYTVGDGRITFVKTGDQVEVIPAELGELPVLRSYEDEEVL
                     AELARRCRQRDFAPGEVIADFGNQTNEVYLLAHGRVEKIGTGPYGDDAVLGVLADGAYF
                     GEQALLDPDAIWEFTARAATAATVLILSRQDFEQVAQRADTLREHVEQLRSAPEQPTNK
                     YGEKEVALAAGHSGEPDIPHTFVDYEPRPREYELSIAQTVLRIHTRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELINNREFGLLNNCEYDQRIQPHDGVPGPDDMDELLSRRRSTK
                     LFLAHPRAIAAFGRELNKRGLVPETVEISGNRIPTWRGVPIYPCNKIPVTPERTTSIIA
                     MRTGEQDQGVIGLRQSGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            12899..13813
                     /locus_tag="M878_RS63240"
                     /old_locus_tag="M878_14320"
     CDS             12899..13813
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674918.1"
                     /locus_tag="M878_RS63240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14320"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_023546858.1"
                     /sec_met_domain="PALP (E-value: 2.4e-17, bitscore: 62.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPDPLVPRLPSPLQEVGDDRFERYGLRLLLKRDDLIHTHLIGN
                     KWRKLVPNIEAAKGRPLATFGGAYSNHLRATAAAGRLLRLPTVGVVRGEELADRPLNPS
                     LARCAADGMRLHFVDRSTYRRKTEPETLAAILRAAGAEEAYVVPEGGSNGAAVQGCRAL
                     GEELRGHADVVAVACGTGGTLAGLAAGLTAGQRALGVPVLRGGFLERDIQALQERAFGG
                     RTGSWSLDERFHFGGYARTTPELHGFAQDFEDRHGLPVERLYVAKLLYGLVALADEGAF
                     PRGTTIAAVVTGRPFPQGQPASR"
     gene            complement(13795..15390)
                     /locus_tag="M878_RS63245"
                     /old_locus_tag="M878_14325"
     CDS             complement(13795..15390)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544441.1"
                     /locus_tag="M878_RS63245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14325"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_023546859.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAGFAGIARRTPVPAPLLLVAVGLAVSYVPGIP
                     HYTLDPDIVLPLVLPPLLYKEGTESSYLDLRAQMRPVGLLSIGYVLFATFVVGWAAYLV
                     VPGLPLPAALVLGAVVAPTDAVAAAAIARRVGLPSRITTILQGESLLNDATAITAYKVA
                     LAAAVGEGATWAGGIEEFLRAAVGGVLVGLVLMVPIHWLRTHLKEALLQNTLSLLIPFV
                     AYGVAEQFHGSGVLAVVVVAVYLGHRAWEVDFATRLQEDAVWRMVAFLLESAVFALIGL
                     QLPTVLKGLGAYQGVDAAWYAIAVFVVVVAARFAWVFPATFLPRALSRRIREREEGVTW
                     RAPVVTGWAAMRGVVSLAIAFSIPLTVHGGAPFPQRNLILFMTFTTVIGTLVVQGLTLA
                     PLIRLMRFPGRDAQAETLAEANAQAQASRAAERHLDDLLSDERNALPPPLADRLRTVLE
                     RRRNAVWERLGQTNPVTGESVDDTYRRLSREMISAEREVFVKLRDHRYIDDEMLRALLR
                     RLDLEEAAAYREAG"
     gene            15452..15712
                     /locus_tag="M878_RS63250"
                     /old_locus_tag="M878_14330"
     CDS             15452..15712
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="M878_RS63250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14330"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_023546860.1"
                     /transl_table=11
                     /translation="MKQCTHTDALPHPEPDPLDPTCPECLRDGTHPVQLRLCLSCGHVG
                     CCDSSPGRHATQHHEQSGHPVMRTFEPGEDWRWCFVDHVLV"
     misc_feature    complement(15741..15751)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(15866..15879)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            16007..16423
                     /locus_tag="M878_RS63255"
                     /old_locus_tag="M878_14335"
     CDS             16007..16423
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="M878_RS63255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14335"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_009190566.1"
                     /transl_table=11
                     /translation="MSQIAGEPAANQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLD
                     EIEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWT
                     VLSALAGKVSSAVDEDKTVSISLYKQRGAGPGPA"
     gene            16441..17553
                     /locus_tag="M878_RS47795"
                     /old_locus_tag="M878_14340"
     CDS             16441..17553
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136656.1"
                     /locus_tag="M878_RS47795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14340"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_023546861.1"
                     /transl_table=11
                     /translation="MRDEERGTRELPTGDGGAPWSSAGEISGEAPRDGSRRMADGIDGI
                     PEQARPHPVDDSASAGGDGAVQVVQPEEPGGAGPAVHAGARARGRATGGTMSEHERNAE
                     DEALGAEAVQAVQHAPQDRSGARAMFVELRKLDAGSAEYAELRNQLVRMHLPLVEHLAR
                     RFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVR
                     VPRRLQELRLALTTATAELSQLHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLD
                     VPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQI
                     AQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(17605..18054)
                     /locus_tag="M878_RS63260"
                     /old_locus_tag="M878_14345"
     CDS             complement(17605..18054)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072179.1"
                     /locus_tag="M878_RS63260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14345"
                     /product="hypothetical protein"
                     /protein_id="WP_023546862.1"
                     /transl_table=11
                     /translation="MSSEQNPTPDAEAAVAEGPRPRRLTYAALLAALEGIALVAGGLWV
                     FVRGLTGDPDGRQQAVTLGITLVVLALLPLLAARGLLLRRSWSRGPAVITQLMALPIAY
                     NLLKADSMAIPAGIALAVVAVAALVLLVNGQTTRALGIKGPGRAE"
     gene            18242..19210
                     /locus_tag="M878_RS63265"
                     /old_locus_tag="M878_14350"
     CDS             18242..19210
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134762.1"
                     /locus_tag="M878_RS63265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14350"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_023546863.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARRRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRLAADSDDIDLVVALGGDGTVNEVVNGLLHAGPDPDRLPGFAVVPGGSTNVFARALG
                     LPNDPVEATGALLDALREGSERFVGLGLTSGTPGTEDEAVPDRWFTFNAGLGFDAGVVG
                     RVEQQRERGKKSTHGLYVRQVIRQFLGEPNRRRGSITLERPGEDPITDLVVAIISNTAP
                     WTYFGNRPMYTSPKASFDTGVDVLGLRRLSTAAVARYGTQLLTSSPERGPHGRHVVSLH
                     DMDQFTLHSKAPLPLQMDGDHLGLRRSVTFTGVRRALRVIV"
     misc_feature    19298..19313
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.38"
                     /tool="antismash"
     misc_feature    complement(19471..19486)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    19474..19485
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            19542..19799
                     /locus_tag="M878_RS63270"
                     /old_locus_tag="M878_14355"
     CDS             19542..19799
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="M878_RS63270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_14355"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003992873.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVIEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
     misc_feature    complement(20844..20858)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 aggtcaaggg cgtgagcaag gcgcaggccc gggagcgggc gacgcagctg ctggagcgcg
       61 tgggcctggc cgaccgagcc gggtactacc cctcgcagct ctccggcggc cagcagcagc
      121 gggtggcgat cgcccgggcg ctggcgatgg acccgaagct gatgctgttc gacgagccga
      181 cctcggccct ggacccggag ctggtcggcg acgtcctgga cgtcatgcgc gacctcgccg
      241 agtccggcat gacgatggtc gtcgtcaccc atgagatggg cttcgcccgc gaggtgggcg
      301 acagcctggt gttcatggac gagggcgtgg tggtcgaatc gggccatccg cgcgacgtcc
      361 tgacgaaccc ccagcacgag cggacgcagt cgttcctgtc gaaggttctc tgaccgcgca
      421 tccctggagg ggcggtacgg gcttccagta ccgccccttc ctgctgcttc ccctgctgct
      481 tctcctgctg cttctccggc tacttcaccg cgagcagcag cgtgtccgac ggcgagcacc
      541 acaccggccg ggcctccccg aaccccttct cgcgcagcac acgcgcgtgc caacccggcg
      601 agggcatgtc cccgtcggcg tgctcgccgt agatctcgta ccgccgggcg gtgggtccgg
      661 cgaggacggg gtccttggcg gcgacctgcc accagtccgc ccagtccagg gcaccgtccc
      721 gcttggcttg atccatacgc gcgtgccgct gtgcgcgctc ggccgcgttg atccggggcg
      781 tgctgtcgtc gatcatgtgg tccgcgttca tgaagacacc gccgtcgcgg accagctccg
      841 cgacctgacc gtagagggcc gcgaggggtt cgctgtgcag ccagtgcagg gccgtggcgg
      901 tcaggacgca gtcgtaggag tcgtacggca gcttcgccgg ccagtcgggt tccttgaggt
      961 cggcggtgac gagagtgacc cgctcgtcgc actcgaaggt gccgcgcgcg atggccagca
     1021 gggccgggtc gaggtcgacg ccggtgctgg tggcccgcgg gaagcgcttg agcagccggt
     1081 cggtgatgct gccggtgccg caggcgaggt cgaggacgcg cggcgccgta ccggccagcg
     1141 cctcgaccat gtcgagcatg atccggaacc gctcctcccg gtccggcatg taccactcct
     1201 gctgccggtc ccagctcccc tgccaggccg cccagtcggt tccggtactc atggtcatgg
     1261 atccccgtct cccctcgtga tgcgtaatac cctggaagca cgaccggctg ttacccgccc
     1321 gcagacacga ccataaagcg ccctcgtaag gactacaagt ggaactggcc tattactcgg
     1381 attacgccgt acgactcgtc aacagcgagg aaccggcccg gggcaaggac tcgctgacct
     1441 cggtcgaggc cgtccgcgac ctctttggcg ccaactcctc cgcggcccgg cgcaccaccg
     1501 acgccgacgt cacccgcttc cgctcggtac gggccaggct gcgcgcggtc ttcgaggcgg
     1561 ccgaccaggg cgacgagacc ctggccgtgg acctgctgaa ctcactcctg ctggagttcc
     1621 cggtgtcgcc gcagatctcc ggccacgact tccgcgacga cgacggccgc ccgctgtggc
     1681 acatgcacct ggccgaccac ccgtcgaacg cgacggccgg ctacgcggcg atcgcggcca
     1741 tgggcctggc cttccacctc accgagtacg gcgtcgaccg cctgggcctg tgcgaggcag
     1801 ccccctgccg caacgcctac ctcgacacgt ccaccaaccg ctcccggcgc tactgctccg
     1861 accgctgcgc gacccgcgcc aacgtggccg cctaccgggc ccgcaagcgc ctggaggccg
     1921 accggtccgg cagcaacggc ctcgcggccg agaacgccca gcgcaccagc gcgagcggcg
     1981 agcgctgacc ggcggggagc ggccggtacc gaaagcgggc cttgcccagc accagctcgt
     2041 ccggtacgac cccgtagtcc gtgctgtccc cgcccgcgta cgggttgtcc ccgagcaccc
     2101 accagccgcc gtcgcgccgc tccacggcac gcttgacgac cagcaggtcc tgctggaacg
     2161 gatgacgcag gacgacgacg tcccccggcc tgaccgaggc cccgtactgc accagcagcc
     2221 ggtccccgtg ctggagcgcg ggcaccatgg acggcccggt cacctccgcc actccgaagg
     2281 gcgccacagc cctcccccgc tcggtctcct gcgacagttc cggcatcccc ggcacctccc
     2341 cggtccgttc ctccaccagt ctcagtctga ccctggactt ttgtcctaag ccctaggggg
     2401 cgcccgagaa atcgccttcc ccagggagta atgtcgcacc tgagaagacg atcacgagga
     2461 aggaatgctg catgctttcc cgcctgtttg cccccaaggt caaggtcagc gcccactgcg
     2521 acctgccctg cggcgtctac gacccggccc aggcccgcat cgaggcggag tcggtgaagg
     2581 ccgtccagga gaagatggcc ggcaacgacg acccccactt ccaggcacgc gccaccgtca
     2641 tcaaggagca gcgcgcggag ctcgccaagc accacgtctc cgtgctctgg agcgactact
     2701 tcaagccccc gcacttcgag aagtacccgg agctgcacca gctggtcaac gacgccctga
     2761 aggccctctc ggccgccaag gcgtccaccg acccggcgac gggccagaag gcgctggact
     2821 acatcgccca gatcgacaag atcttctggg agaccaagaa ggcctgaggc tttctctccc
     2881 tttgaaaggg gcccggtcgg catctccgac cgggcccctt gcctatgccc tccatgagcg
     2941 ggcgccgggt cagcggcggc agacgaggat gccgcccaga cacgtgacct caaaggcccc
     3001 gtgctgggcg atatgaccga ggagaatcgt gcgggcccgc tcgatcgtgg cgtcgaaggg
     3061 cacgtcgtgc tggtccgccc acgcccgata ggaggccatg tgcgcgatga ccggcccggg
     3121 atcctgcacc ctgatggtgc cgggcagccc gatcgcctcc acccggccga actcctcccc
     3181 caggaaggac ggagccttct ccaggcagaa gcgggcactg agcgagatac gagccgggcc
     3241 gcgcccggtg ccgagcacgt cgcctgcggc ccgctgccac aggtcgtcga gttcggcctt
     3301 gtcccggtca ctgttggtgg agacgatcac cagcccctcg cgggcaacca cgcgggacag
     3361 ctccctgacc gcctgaggga tgtccgggac gtggtagagc atgtgcaggg ccaaggcggc
     3421 atcgacgctc tccgtggcca acggcaggcg ggtggcatcc gccacggcga cggggcccgg
     3481 cacgccggcg aggatgccgg gagcgatgtc caagccgagc agggccaggt cgggccggtc
     3541 ctcgcggagc cgctggatga acttgccgtt gccgcagccg acatcgacca cgcgcccgcg
     3601 tacgcccctc agctgctcgg cgacgatgcc aggcaggtca tagcggggcg tctgccactg
     3661 atagagcgac tggcgggcag ccagatcccg gtcactgctg taggcacttc cggcgagacg
     3721 gccccggtcg gtgacggcgg cgtcgtgtgc ggcggacagt tcggtcacgt cggcagctcc
     3781 ggtgggtggg atgggggtac cgcccacgcc cttgaggcag tgggggaggg tgagcccgcg
     3841 aggacggccg tgtgctggag tcgttcgcgt aggtgtgcgg cctgcgcggc tccaccgtac
     3901 tgcggctcgc ccagctcccg gcccagagcg gtgagccgac gcacgatact ggccgacata
     3961 cgctccggat gcccgcctgt tctgcccccc ggcacttctt ccgcgcggag acgcgcctgg
     4021 cgttcgccga gtcacttcac ctcaaccccg gctcgctgct tgccggaatg ctccaggtat
     4081 aagtgagtcc gtgttcgtga gtacagtgcg cccagccagg cgcacgtgca atggctgtgt
     4141 ggcgtccgcc ggcctatggc ctgagcgtta tggctcaatc tccagttgca cctcgttact
     4201 gcccccctgg aggccggacg tgaggcattc cgtgggtagt tcctggggca ggccggtgat
     4261 ggtccgccgt acgggatgcc cttggccacg tccctcgacg actcgacctc gctggatcac
     4321 gaccaggacc cctgtgacgc ggagggtcgt ggcgctgtcg taggcgatca gcgacctgcc
     4381 gccgtcggcg taccggatgg tttccgtccc gcttccgccg gacacggcga cgcaggaggc
     4441 agccggcgcc tccgagttga aggagccggt ggcgggaacg gtccggccgt gggcaccgca
     4501 ggtgtacgta atgtccgcgt gaacatgggt cggcccggcc aggagcttga gcggcgggtc
     4561 gtaacggctc tcgctatgcc cgacgcagcc gacgctcccc tcctcgtccg ccgtggcccg
     4621 accgatcggc gcccacacca acgacgaccc cgccagcatc acggacccca gagccaccgc
     4681 gacaccacgc ctaccgaaca tgtttccctc cagctacgtc ctgcaccact aacggcactt
     4741 ggcctaccca gaggcgcatc ccgtgccccg gcgtctcgaa gcgcacgacc cgcgcacgtt
     4801 ccgcttcgtg cgcggccacg cgcgcctgta ctcgcaccgc acgccatacg gtcggctgcg
     4861 gtcgcatgga acctggaaca cggcgggtag caagcgccgg acgagtcctc gtcgagcagg
     4921 aaacgagcag gaggagatct ccagtgggcc gtactaccgt tgcagccgcc accgtcgcga
     4981 gagggcgtat cttcgccatg atggacgcgg acggggacgg ggtcatctcg gcgcacgact
     5041 acctctcccg ggtcgatcgg gccgtccagg ccacgggacg ctcggaggac gacccactgg
     5101 tcgtcgccgc ccgcgggcaa gcccacaagg cgtggggggc tatggacgcg aacggcgacg
     5161 ggaagctgac cttcgaggaa tacgacgcat gggtcggcgc cgacaagttc gacaacatct
     5221 gccggttcgc cctgggctca ctgttcgacc tcgccgacgc cgacggggac ggcgccctgg
     5281 acaagaccga attcacgatg ctgcgcaccg cgctgaacaa tgcgcccgga aacgccgctt
     5341 ccgcgttcaa cgcattggac accgacggcg acggcttggt ggttcgtgat gagtacctgg
     5401 cgtcgatccg ctcctacgtc atcggcgacg cctcgcctat gggcgaggcc ctgtattagg
     5461 cactgccccg acggcggcct ctgggtatgc gccgtgtgta cgtgccgtca gtggaactgc
     5521 ggcacgatca gacagatccc gtacgccacc accgcagcgc aggcgaggaa gcacagggcg
     5581 gcctgggctc ggcccgcggt ggcggaaccg gagcggtcgg cttccgcccg ggacaggccg
     5641 aggacaccga aggtgaagac gacgaccacg gcgaccgtga caccgaggct gaccgcggcg
     5701 accttgccga gggcggacca gtcgacatgc atgaggggct cccggagggt caggcggccg
     5761 cgccgacgtg cggcggggcc ggggtgcgga gggtgacgtc gtggtggtcg ttgacgttgt
     5821 cggcgcgcac cggattgcgg cgggacgcgg cgacgatgac ggcggcgagg gccagggcga
     5881 ccagcgcgat gaccgccgta ccgacgttgc cgccgtgctt gaccacgctc gccgcgaggc
     5941 cgccgaccag cgcggcggac ggcagggtga tcagccaggc cagcaccatc cggccggcca
     6001 cgccccagcg gacctccgcg agacggcggc cgagaccggc gccgaggatg ctgcccgagg
     6061 cgacctgcgt ggtggacagc gcgaagccga ggtgagcgga ggtgaggatc accgtcgtgg
     6121 aggccgtctc ggcggcgaag ccctgcggcg actggatctc cgccagcccc ttgcccatgg
     6181 tgcggatgat ccgccagccg cccaggtagg tgcccagacc gatggccaga cccgccgcgc
     6241 cgatcaccca caccggcggg cccgcttcat ggccgagcgc gcccgccgag atcagcgtca
     6301 gcgtgatgac gcccatggtc ttctgggcgt cgttggtgcc gtgcgccagg gacacgaggg
     6361 acgccgaggc gatctggccg aggcggaagc ccttggtcac cgagtcccga cgggcgcgag
     6421 cgctgagcct gtaggcgagg taggtggcga ccagggcggc cacgccggcc accaccggag
     6481 aggccacagc cgggatcagc accttctcga caaccttgtc aaagtgcact ccgtgggagc
     6541 ccgcaccgac ccagactgca ccgatcagac cgccgaagag ggcgtgggag gaactggagg
     6601 gcaggccggc gagccaggtc accaggttcc acaggatcgc cccgaccagc ccggcgaaga
     6661 tcatcgccgg gctgaccagt gtgtcgtcca cgatcccgcc ggagatggtc ctggccacct
     6721 cggtggacag aaaggcgccg acgatgttga ggactccgct gaccagaacc gcggtgcgcg
     6781 gcttgagcgc gccggtggcg atggaggtcg ccatcgcgtt cgcggtgtcg tggaatccgt
     6841 tcgtgaagtc gaacgccagt gccgtgacga tgacgaccgc cacgaggaac gtgatgtggt
     6901 ccattccccg aggcaagcaa gggccggcca atgcgcggcg aactgaaggc gaacggagtg
     6961 tcgaagatgg gggactctgt tgtgcattcc tgtgcggaat cgtgccatct cgcgatgtca
     7021 gtgccctgtg ccacgctgtg cagatgaccc tggacgacct cagacggctg cggcgcgtcc
     7081 gtgaccgcat ggaccgcgag tacgccgagc cgctcgacat gaccgagctg gcccgcggcg
     7141 cccatatgtc gccgggccat ttccagcgca gcttccgcaa ggccttcggc gagacgccgt
     7201 acagctatct gatgacgcgc aggatcgagc gggccaaggc gctgctgcgc cggggcgacc
     7261 tcaccgtcac cgaggtctgc ctcgccgtgg gctgtacgtc actcgggtcc ttcagctccc
     7321 gcttcaccga gctggtcggc gagacaccga gcgcctaccg ggcccgggac cacgaggaga
     7381 gcgccgtgat cccgtcctgc gtggcccgca cgttcacccg cccgcgccgc cggccctact
     7441 gacccatacg tcacccgccc gcgccgccgg ccctactgac ccgtccgccc ccgacagcac
     7501 aggcgtgccc gggtcgcgcg cgtcccggcc cggatgggcc tagcgtgact gcatggacgt
     7561 gaaactcaag cagtgcttca tcgcggtgga cgaccatgac aaggcgctcg ccttctaccg
     7621 cgacgtgctc ggcctggagg tccgcaacga cgtgggcttc gagggcatgc gctgggtgac
     7681 cctgggctca ccgctccagc cggacgtcga gatcgtgctg gagccgcccg gcgccaaccc
     7741 ggacgcctcc cccgccgacc ggcaggcgat ggccgaactg ctcgccaagg gcatgctccg
     7801 gggtgtcatc ttcacgaccg aggactgcga cgcgctgtac gagcgggtgc gggagtccgg
     7861 cgccgatgtg ctccaggagc cgacggacca gccgtacggg gtccgtgact gcgccttccg
     7921 ggacccggcg ggcaaccagc tccgcttcct ccagcgcccc gcggaatgac cgacctgcgg
     7981 aatgaacggc ccgcgtgaat tccccgggcc cgccagggaa ttcacgccta cactccccgc
     8041 atgatcattc gctggacgta cgccttcgtc gaccggcccg ccggccggct gcgcgaggct
     8101 cgcgccttct ggacggctgt caccggcacc cacgcgtccg aaccccgcgg cgaacagggc
     8161 gagttcctga ccctgctgcc cgaggaggcc gccgggacgg acgcgtgcgt gaagctccag
     8221 ggcgtcgccg agggcgacgg cggcgcccat ctcgacctct gcgccgagga cgtacgggag
     8281 ttgaccgcga acgcccggga actcggcgcg gagctggtgg cggaccacgg cgactgggtc
     8341 gtactgcgct ctccggcggg gcagtcgttc tgtgccgtgc cctggcacgg ggagacggta
     8401 cgaccgccgg tggtggcggg cagccggctg gaccaggtct gcctcgacat cccgccgtcc
     8461 cggcacgccg ccgagtcgga cttctgggcc accctcaccg gctgggaacg actgaagggg
     8521 tcccgcccgg agttcgaggt gctgaagccg ccggcgggac tacccgtccg gatcctgctc
     8581 cagcggctcg acgacgagcg ccccgcctcc gcccatccgg acctcgcctg cgcggacatc
     8641 gcggcagtcc gcgcccggca cgaggagtac ggggccgccc ccgtgcacca tggcccgcac
     8701 tggacggtga tgcgcgaccc ggccggcggc gtctactgcc tgaccggccg agacccggag
     8761 acgggcggcc ttccggccgc cggtcggtga acgcccggcg cgcaggcccg caagacagcc
     8821 ggtgcgcagg cccacacgac aggggtaccg gtcaccccca ggactccacc tccaccacgg
     8881 cgtcggccgg cagcggcccg tacacatgcg ggaactcctc cccgcccggc tccatggcct
     8941 cgtacttcac cggtgcagcg accaaggccg ggtccacgac caggacgacc agctcgtccg
     9001 gaccgtcgta gtcgccgtag aggaacgcgg cgatgcgcgg gagctgttcg cgggtggaga
     9061 agtggatgaa gccctcctcc tggagggtgc ggcctcgggt cgacacctcg taggcgccgc
     9121 gctcgcgggc cgcttcccac agggagcgtt cggtgatgtg gaagatgcgg ggcagtttcg
     9181 gcatgcgccc acggtacggc gtccggtacg gcgtcggcgg cgggctcagc gctgcctcgt
     9241 gtacgtccgc acgagcacgc cgttggtgaa ggtgcgcacc ccgtcgaggg tgaactcctt
     9301 gatgtcgagt ccggtgccga acatgggcat gcccgtgccg tagacgagcg ggtaggtctt
     9361 gatgacgagt tcgtcgatct cgtccagcag ctctccggcg aggcgcgcac cgccgcacag
     9421 atagatgtcc aggccgccct cctccgcctt cagtgcgtgg acccggccga gcaggtcgtc
     9481 ggcgatgatc tcgacgtgcg ggtcggggga cacggccagg ctgcgggagg cgacgtactc
     9541 gcgcagatgg gcgtaggggc tggtgatgcc ctccttgagg gccagctcgt agctgccccg
     9601 gccctggatg acggtgtcga accgcttgtt ctccaggtgg tcgaggccga gcggcctgcg
     9661 gccatgggtg gccatggtct ccgggaactc cgtcttgagg aagtcgaggt actcctcgtt
     9721 catgaagcgg aacatcgccg aggcgtcgcc ctgctcgtcg cctatgaagc cgtcgagcga
     9781 acaggcgatg aagtagctga gcttgcgcaa acctgtctct tttcaggagg agttggtacg
     9841 accgggcggc caaccactcc atttgtagta ctccagtcgt agtggttgca agacgtttcg
     9901 gaggtctgcc agaagcggga gaagtggttc cggacaggca cgagcggccg gtcccgcaca
     9961 ctgtggggat gtgcgggacc ggggtctgtc ctggcctcga tcagccgctg cgccgggtga
    10021 cgaactcggc gagcgccagc agaccgcccg ccgcctcggg cgcggggacc gcgcgggaca
    10081 gctcctgcac cgcgcgggcc atccggtcgg ccgcctcggc ctgcgcccag tcccgcccgc
    10141 ccgcccgctc cacggccagt gccgtacgca cgatgccctc ggcgtcaccg gagacgtacg
    10201 gctcgtcgta cagctcggcg agttcggctg ccgcttccgt gccggaggac agggccgcca
    10261 ccacgggcag cgacttcttg cgggccgcga gatccgcgcc ggccggcttc ccggtgcgcc
    10321 gcgggtcgcc ccatatgccg atgacgtcgt cgatcagctg gaaggcgagc ccggcctggc
    10381 ggccgaagcc gtccagcgcc gccacgtcct cgccgtcggc gcccgcgtac agcgcgccga
    10441 gggcgcaggc gcagcccagc agcgcgccgg tcttcgcctc ggccatggcg agcacctcgt
    10501 cgagggtgac ctcgcccggg gcgcggcgct ccatgtccac gtcggtgtgc tggccggcgc
    10561 acagttccac gacgcagtcc gcgagccggg ccgccgccgg gccggacgcc gggtgcgggt
    10621 cctcggcgag catccgcagg gccagcgcct gcagggcgtc accggcgagg atcgcgtcgg
    10681 cagtgccgaa cacggtccag gccgtgggcc ggtgccggcg ggaggcgtcc cggtccatca
    10741 cgtcgtcgtg caacagggtg aagttgtgga ccagttcgac cgccaccgcc gcccggaccg
    10801 ccgccgtacg gcccgcgggt ccgccgaggg cggtggccgc cgcgaggacg agcgcgggcc
    10861 ggatcgcctt gccggcgttg ccgcgcgccg gggtgccgtc cgcgtgctgc cagccgaagt
    10921 ggtagagcgc gatccggcgc atggagccgg gcagcgactc cagagccgcg cgcagctccg
    10981 ggtcgaccag ggtccgggtg cgctccagca gcgccaccgc ctcctgtcct tcgagacgcg
    11041 cctcgggatg tcgctcggga tgtcccccgg cctgaccggc atcggcgtca ccggtcctcc
    11101 cccgccgttc ccccgccgtg ccggggtgcg gcacggcggg ggaacgctgt tcggtctccg
    11161 tcatgaactc ggccatgtct ccccctcgcc aggtccgcgg acaccggcgt caccggcccg
    11221 gccggacgca tattccgagg gtctaccctc gccgacgagc gggaacacga ccgcgaagtg
    11281 cggaaacgtc acctccaccg gccgatctcg acgttctcca gcacgccgag cgcgtcgggc
    11341 accagcacgg cggccgagta gtaggccgtc accaggtact tgatgatggc ctgttcgttg
    11401 atgcccatga aacggacgga caggctgggc tcgatctcgt ccgggatgcc ggactgcctc
    11461 aggccgatga caccctggtc ctgctcgccg gtacgcatgg cgatgatcga ggtcgtgcgc
    11521 tccggggtga ccgggatctt gttgcagggg tagatcggca ctccgcgcca ggtcgggatg
    11581 cggttgccgc tgatctcgac ggtctccggg accagtcccc gcttgttcag ctcgcgcccg
    11641 aaggccgcga tcgcgcgcgg gtgggccagg aacagcttgg tgctgcgccg gcggctcagc
    11701 agctcgtcca tgtcgtccgg gccgggcaca ccgtcgtgcg gctggatccg ctggtcgtac
    11761 tcgcagttgt tcagcaggcc gaattcgcgg ttgttgatca gctcgtgctc ctggcgctcc
    11821 ttgagcgcct cgaccgtgag cctgagctgc tgctcggtct ggttcatcgg ctggttgtac
    11881 aggtcggcca cgcgcgtgtg gatgcgcagc acggtctggg cgatgctcag ctcgtactcg
    11941 cggggccggg gctcgtagtc cacgaaggtg tgcgggatgt cgggctcgcc ggagtgaccg
    12001 gccgccagcg cgacctcttt ctcgccgtac ttgttggtcg gctgctccgg ggccgagcga
    12061 agctgctcga cgtgttcgcg cagggtgtcc gcgcgctggg cgacctgctc gaagtcctgg
    12121 cgactgagga tcagcacggt cgccgcggtg gccgcgcggg cggtgaactc ccagatggcg
    12181 tccgggtcca gcagtgcctg ctcgccgaag taggcgccgt cggcgaggac tccgaggacg
    12241 gcgtcgtcgc cgtaggggcc ggtgccgatc ttctcgaccc tgccgtgtgc cagtaggtac
    12301 acctcattgg tctggttgcc gaagtcggcg atcacctcgc cgggcgcgaa gtcacgctga
    12361 cggcagcggc gggccagctc cgccagcacc tcctcgtcct cgtacgagcg caggaccggc
    12421 agctcgccga gttcggccgg gatgacctcg acctggtccc cggtcttcac gaaggtgatg
    12481 cgaccgtcgc cgacggtgta cgccagtcgc ctgttgaccc ggtatgtgcc gccatgtacg
    12541 tctacccacg ggagcgtgcg cagcagccag cgggagctga tctcctgcat ctgcggaacg
    12601 gacttggttg tggtggccag gttccgcgct gccgccgtcc cgagggactg ctgcggcttg
    12661 ccctgatccg tgcggacctc ttcgcctacc gacatagaga attgcctccc aggtattccc
    12721 ggtgccgaat cgcagggggc accggtctcg gcacccgagc cttccatcac ggatcgcggt
    12781 cgcgccatta cccgaacggg cgggaataga tcatcggatt actgggcatg acgaaggacc
    12841 tgtccagtcc cctgcagcgc cctcggccgt atgccccgca ccgggtgaca atgaagcggt
    12901 gaccagcccc gatccgctcg ttccccggct cccctctcct ctccaagagg tcggggacga
    12961 ccggttcgag cggtacggtc tgcggctgct cctcaaacgc gacgacctga tccacaccca
    13021 cctcatcggc aacaaatggc gcaagctcgt gccgaacatc gaggcggcga agggccggcc
    13081 gctggccacc ttcggcgggg cctactccaa tcacctgcgc gccaccgccg ccgcgggccg
    13141 ccttctccgg ctcccgaccg tcggcgtggt ccgcggcgag gaactggccg accgtccgct
    13201 caacccctcc ctggcccggt gcgcggcgga cggcatgcgg ctgcacttcg tcgacagatc
    13261 gacgtaccga cgcaagaccg agccggagac cctggccgcg atcttgcgcg cggccggtgc
    13321 ggaggaggcg tacgtcgtgc ccgagggcgg cagcaacggc gcggccgtac agggctgccg
    13381 ggcgctggga gaggaactgc gcgggcacgc cgacgtcgtc gcggtcgcct gcggcaccgg
    13441 tggcacgctc gcggggctgg ccgccgggct gacggcggga cagcgggcgc tcggcgtacc
    13501 ggtactcagg ggcggcttcc tggagcgtga catacaagcg ctgcaggaac gtgccttcgg
    13561 cggccgtacc ggctcctggt ccctggacga gcgcttccac ttcggcggct acgcccgtac
    13621 gacacccgaa ctgcacggct tcgcccagga cttcgaggac cgccacgggc tgcctgtcga
    13681 gcgtctctat gtcgccaagt tgctctacgg acttgtcgcc ctcgcggacg agggcgcctt
    13741 cccgcgcggg acgacgatcg ccgccgtcgt gaccgggcgg ccgttcccgc agggtcaacc
    13801 cgcctcccga taggccgccg cctcctccag gtccaggcgt ctgaggagcg cgcgcagcat
    13861 ctcgtcgtcg atgtagcggt ggtcgcggag cttgacgaag acctcgcgtt cggcgctgat
    13921 catctcgcgg gacaggcggc ggtaggtgtc gtcgacggac tcgccggtga cggggttggt
    13981 ctggccgagg cgctcccaga cggcgttgcg gcggcgctcc aggaccgtgc gcaggcggtc
    14041 ggcgagcggc gggggcaggg cgttgcgctc gtcggagagg aggtcgtcga gatggcgctc
    14101 ggcggcccgg gaggcctgtg cctgggcgtt ggcctcggcg agcgtctcgg cctgcgcatc
    14161 gcggcccggg aagcgcatca ggcggatcag cggcgcgagc gtcaggccct gcaccacgag
    14221 ggtgccgatg accgtggtga aggtcatgaa gaggatcagg ttccgctgcg ggaagggggc
    14281 gccgccgtgc accgtgagcg ggatcgagaa cgcgatggcc agggacacca ctccgcgcat
    14341 ggcggcccac cccgtcacga ccggcgcccg ccaggtgaca ccctcctcgc gctccctgat
    14401 ccggcgggag agcgcgcggg gcaggaaggt cgccgggaac acccacgcga agcgggccgc
    14461 cacgaccacg acgaagaccg cgatcgcgta ccaggccgcg tcgaccccct ggtacgcgcc
    14521 caatcccttg aggacggtgg gcagttgcag gccgatcagc gcgaagaccg ccgattccag
    14581 tagaaaggcg accatccgcc acaccgcgtc ctcctggagc cgggtggcga agtcgacctc
    14641 ccacgcgcgg tgcccgagat acaccgcgac cacgacgacc gcgaggacgc cggagccgtg
    14701 gaactgctcg gccacgccgt aggcgacgaa cgggatcagc agcgagaggg tgttctgcag
    14761 cagcgcctcc ttcagatggg tgcgcagcca gtggatcggc accatgagca cgagtccgac
    14821 gagcaccccg ccgaccgcgg cccgcaggaa ctcctcgatg ccgcccgccc aggtggcgcc
    14881 ctcgccgacg gccgcggcga gggccacctt gtaggcggtg atcgcggtgg cgtcgttcag
    14941 cagggactcg ccctggagga tggtggtgat ccgggacggc aggccgaccc ggcgcgcgat
    15001 cgccgcggcc gcgaccgcgt cggtcggcgc gaccaccgcg cccagcacca gcgcggcggg
    15061 cagcggcagc cccggtacga cgagataggc ggcccagccg acgacgaagg tcgcgaagag
    15121 cacgtacccg atcgacagca gccccacggg ccgcatctgg gcgcgcagat cgaggtacga
    15181 gctctcggtg ccctccttgt agagcagcgg gggcagcacc agcggcagga cgatgtccgg
    15241 gtccagcgtg tagtgcggga tccccgggac gtacgagacg gccaggccga ccgcgaccag
    15301 cagcaggggc gccgggaccg gggtgcgccg ggcgatcccc gcgaaccccg cactgcccgc
    15361 caccagcaac agcagcggca tcacgtccat ggtcctcgcc caccctcgtt ttccgcgcgg
    15421 ccacccgcac acccgtcgta atctggcaat catgaaacag tgcacgcaca ccgacgcgct
    15481 gccgcacccg gaaccggatc cgctcgaccc gacctgcccg gagtgcctgc gggacggcac
    15541 gcacccggtg cagctgcggc tgtgtctcag ctgcggccat gtcggctgtt gcgactcctc
    15601 gcccgggcgg cacgcgacgc agcaccacga gcagtccggt caccccgtga tgcggacctt
    15661 cgagcccggc gaggactggc ggtggtgctt cgtggaccac gtactggtgt gatcgtgttc
    15721 ccgtccgacc gcgttctcgt gtgacactgc atgcgacggc ggccgcacga cggttcgagc
    15781 gtctgacgtc tgggtacgtc aacccggcgc gcgctcttcc catttgggcc cgcaaaccct
    15841 ctagacacgg agcgtataca cagctttact gtgagtgacg ccaggggggt tggggtcccg
    15901 ggacaggaac gttcggagcg cgatagcgtc accgccgaac cacgtacgcg ttaccccggg
    15961 gggcgaccct cggccccgta aagcttgtac caccatggag gtgagggtgt cccagatcgc
    16021 aggcgagccc gcggcgaatc aggacttcgt ggaagtccgg ctgccggccg cgggtgccta
    16081 cctgtcggtg ctgcggacgg ccacggccgg tctcgcggcc cgcttggact tcaccctgga
    16141 cgagatcgag gacctgcgca tcgccgtgga cgaggcctgc gcgatcctgc tccaacaggc
    16201 tgtgcccggc tccgtgctca gctgtgtctt ccggctcgtc gacgactcgc tggaggtcac
    16261 ggtctcggcg ccgaccacgg acggtcacgc cccctcgcgg gacaccttcg cctggaccgt
    16321 gctgtcggcc ctcgcaggca aggtctcgtc cgcagtcgac gaggacaaga ccgtgtcgat
    16381 cagcctctac aaacagcgcg gcgcgggccc cggcccggcg tgaggaacgg ggacggtccg
    16441 gtgcgggacg aagagcgcgg cacacgcgag ctgccgaccg gggacggggg tgccccctgg
    16501 tcgagcgcgg gcgagatctc cggggaagcc ccccgggacg gttcccggcg catggcggac
    16561 ggcatcgacg gcatccccga gcaggccagg ccgcacccgg tggacgactc cgcgagtgcc
    16621 ggaggtgacg gcgcggtgca ggtcgtacag ccggaggaac ccggcggcgc cggacccgcc
    16681 gtccacgcgg gagccagggc tcggggaagg gctacgggcg ggacgatgag cgagcacgag
    16741 cgaaacgccg aggacgaggc gctgggcgcg gaggccgtgc aggccgtaca gcacgccccg
    16801 caggaccgca gcggtgcgcg ggcgatgttc gtcgagctgc gcaagctgga cgccggcagc
    16861 gcggagtacg cggagctgcg caatcagctg gtccgtatgc acctgccgct cgtggagcac
    16921 ctggcacgcc ggttccgcaa ccgcggcgag ccgctggacg atctcaccca ggtcgccacg
    16981 atcggtctga tcaagtccgt cgaccggttc gacccggagc gcggcgtgga gttctccacg
    17041 tacgccaccc cgaccgtggt cggcgagatc aagcggcact tccgcgacaa gggctgggcg
    17101 gtccgggtgc cgcgccggct gcaggaactg cggctcgcgc tgaccacggc gacggccgag
    17161 ctgtcccagc tgcacggccg ctcgcccacg gtccacgagc tggccgagaa gctcgcgatc
    17221 tccgaggagg aggtcctgga gggcctggag tccgccaacg cgtactccac gctgtccctg
    17281 gacgtccccg acaccgacga cgagtcgccc gcggtcgccg acaccctcgg cgcggaggac
    17341 gaggcgctgg agggcgtgga gtaccgggag tcgttgaagc cgctgctgga ggatctcccg
    17401 ccgcgggaga agcggatcct gctgctgcgc ttcttcggga acatgaccca gtcgcagatc
    17461 gcgcaggagg tcggcatctc ccagatgcac gtctcccggc tgctggcccg cacgctggcc
    17521 cagctgcggg agaagctgct cgtcgaggag tagccgggga gcgagcagag cggacgagca
    17581 gagcgcctgg gtctgcgccc ggttctactc ggcgcgaccc ggtcccttga tgccgagggc
    17641 ccgggtcgtc tggccgttga cgagcagtac gagcgccgcc acggctacga cggccagggc
    17701 gatcccggcc gggatggcca tgctgtcggc cttgagcagg ttgtaggcga tcggcagcgc
    17761 catgagctgg gtgatcaccg ccgggccccg gctccagctg cgccgcagca gcagtccccg
    17821 cgcggcgagc agcggcagca gcgcgagcac gaccagcgtg atacccaggg tcacggcctg
    17881 ctgccggccg tccgggtcac cggtgagccc ccgcacgaac acccacaggc cgccggccac
    17941 cagcgcgatg ccttccaggg cggccagcag ggcggcatac gtcagccgac gggggcgggg
    18001 cccctcggct acggctgctt cggcatccgg ggtcgggttc tgctcactgc tcaccccagc
    18061 agggtagccg ccgggccctg aggaccactg gcgggtgcgc gcggcgctgc gaaaccgacg
    18121 gcactgcggc tcctcaaagg gcgcgtggct gtatcgatat gtcgaggctc acgcccctgc
    18181 ctcttaccgg atccctacct cggtgtaggc cgggtaccgc cgggtaggta cgctgccatc
    18241 catgcgtgca cttctcgtgg tcaatccggc ggctaccacc acaagcgcac gcaggcgcga
    18301 cgtcctgatc cacgcactgg cgagcgagat gaagctggag gcggtcacca ccgagtaccg
    18361 cggccacgcg cgcgacctcg gccggctggc ggcggacagc gacgacatcg acctcgtggt
    18421 ggccctcggc ggcgacggca cggtcaacga ggtcgtcaac ggcctcctgc acgccggccc
    18481 cgacccggac cggctgcccg gcttcgccgt ggtccccggc ggctccacca acgtcttcgc
    18541 ccgcgccctc ggcctgccca acgacccggt ggaagccacc ggcgccctgc tggacgcgct
    18601 gcgcgagggc agtgagcggt tcgtcggcct cggcctgacc tcgggcacgc ccggcactga
    18661 ggacgaggcg gtcccggacc ggtggttcac cttcaacgcc ggactcggct tcgacgcggg
    18721 cgtcgtcggc cgggtcgagc agcagcgcga gcgcggcaag aagtcgacac acgggctgta
    18781 cgtacgacag gtgatccggc agttcctcgg cgaaccgaac cggcggcgcg gctcgatcac
    18841 actggagcgg cccggcgagg acccgatcac cgatcttgtg gtcgccataa tctcgaacac
    18901 ggccccttgg acgtatttcg gcaatcgccc catgtacacg tcgcctaagg cctcgttcga
    18961 caccggcgtc gacgtcctgg gtctgcgccg cctctcgacg gccgcggttg cccggtatgg
    19021 cacccagttg ctcacttcgt cccccgagcg cggaccccac ggcaggcacg tggtctcgct
    19081 gcacgacatg gaccagttca ccttgcattc gaaggcgccc ctccccctgc agatggacgg
    19141 cgaccacctc ggactgcgta gaagcgtgac gttcacaggc gtacgccgtg cactgcgtgt
    19201 gattgtgtga gcggaagacc ccaaagtcct ttcactcgaa cgtttaggcc aggatccacc
    19261 ccatggaagt acggctgtga cctagtcgac accgaggaat caaaaaaact ttcctgaagg
    19321 ggttgtatcc gccgctgagg tttgcgagtc tctacgtggc gatcgggacg gcccgcaaca
    19381 ccggcctccg ctggtcacca gaacccctct tcaaaccaag gaccacgccg gggaagactc
    19441 ggcggtcggc ccttcacttg ttgagggatt cgtgaaagcg ttcacattca caagcaacct
    19501 gtacgtaata cgttcagaga aaccaaggag aggtagcagc catggactgg cgtcacaacg
    19561 ccgtttgccg cgaggaagac cccgagctct tcttccccat cggcaacacc ggtcctgcgc
    19621 tgctgcagat cgaggaagcc aaggccgtct gccgtcgctg cccggtgatc gagcagtgtc
    19681 tgcagtgggc gctcgagtcc ggtcaggact ccggcgtctg gggtggtctc agcgaggacg
    19741 agcgccgcgc catgaagcgc cgcgccgccc gcaaccgggc ccgtcaggcc tccgcctgac
    19801 atacccaccc ctgctgacag cctgagcttg gcggcgcgtg cagtacgcgc gcatctcccg
    19861 cccccgagcc gcagcgcgca gtatcccccg atgccgctag cgatttagca gagcagcaac
    19921 gagcacgagc ctcggaccca tggcggtccg gggctttttg ctgtccgcaa ggggccgccg
    19981 gcgtacggca gttgggtcac ttctgcgccc gcaccggaat gtcgaggatc acccgggtcc
    20041 cccgccccgg cgccgggacc atgtcgaagg agccgcccaa ctccccctcc accagcgtcc
    20101 gtacgatctg cagccccagg ttgcccgagc gatgtgggtc gaagtcctcg ggcaggccga
    20161 ccccgtcgtc ctggacggtg acgaggaggc gggcctcctt ggtggtgccg ccacggaccg
    20221 cggagacctc taccgtgccg gtgtcgccct cgcaaaagcc gtgctccagg gcgttctgca
    20281 agatctcggt gaggaccatc gacagcgggg tggcgacctc ggcgtcgagt atcccgaagc
    20341 ggccggtgcg ccggccggtc accttgcccg gcgagatctc ggcgaccatc gccagcacgc
    20401 ggtcggcgat gtcgtcgaac tccacgcgct catccaggtt ctgagacagc gtctcatgca
    20461 cgatggcgat cgagccgacc cggcggacgg cctcctccag ggcctcccgg cctcgctcgg
    20521 actcgatacg ccgggcctgc agccgcagca gcgcggcaac cgtctggagg ttgttcttca
    20581 cccggtggtg gatctcccgg atggtcgcgt ccttggtgat caactcgcgc tcgcggcgcc
    20641 gcagttcggt gacgtcccgg cacagcacca gggatccgat ccgggtgccc ttgggcttga
    20701 gcgggatcgc ccggaactgg atcaccccgt cgttggcctc gatctcgaac tcgcgcggcg
    20761 cccagccgct ggccagcttg acgagcgcct cgtccaccgg accgcgggtc ggggccagct
    20821 cggcggtggt ctgcccgagg tgctggccga ccaggtcggc ggcgaggccg agccggtggt
    20881 aggcggacag cgcgttcggg gaggcgtact ggacgacgcc gtccgcgtcc agccggatca
    20941 ggccgtcgcc gacacgcggc gaggcatcca tgtcgacctg ctggccgggg aaggggaacg
    21001 atcctgcagc gatcatctgc gccaggtccg aggcactctg gagataggtc agctccagcc
    21061 ggctcggggt gcggacggtc agcagattgg tgttgcgggc gatgacgccg aggacgcggc
    21121 cctcgcgtcg tacggggatg gactcgaccc gtaccgggac ctcttcgcgc cactcc
//
