LOCUS       NZ_CM002285            27490 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2820506
            Orig. end                         :: 2847996
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27490
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="19"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..27490
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27490
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:17490](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17490
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            complement(145..3459)
                     /locus_tag="M878_RS62020"
                     /old_locus_tag="M878_12990"
     CDS             complement(145..3459)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609628.1"
                     /locus_tag="M878_RS62020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_12990"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_031224782.1"
                     /transl_table=11
                     /translation="MRFGVLGPLAVWDDEGVAVRVPEAKVRTLLADLLAHDGGPVSADR
                     LIHDLWGDSPPGRPAGALQAKVSQLRRVLGRDRVVHQPAGYRLRLDSDHDEVDAVRFRG
                     LVDRARDVAAPSARAALLTEALELWRGPAYADFADQEFVRGAVQRLTEQRLSVLEEQAE
                     ARLAAGDQVLLAGELADLVARHPLRERLRALQMRALYTAGRQSEALAAYEDLRACLIAD
                     LGVEPSPELAALHQAVLRQAPELTGTPWNTDRPRPRTERDAISPRPPAEANAHVSRAPS
                     NLPASLTPLIGRDKALAHLAALLRATRLVTLTGAGGVGKTRLAVAAADAVHSGGSAEVL
                     PDGTWFVEFSGIRHGTAADLAQVVTAALGISDHAPSALPVSGTGTRSPAHHLAAVLRDR
                     RTLLVLDNCEHVVDAAAELAALLLRTAPGLRVLATSQEPLGLPGEEVFLVEPLPTADAV
                     RLFTERAAAAAPGFSLASDGGAGSDRTAVTEICRRLDGIPLALELAATRVRALGVRELA
                     ARLGDRFQLLTSGRRGAPERQQTLRAMIDWSWELLSAPERIVLRRMAAFSDGCDLQAAE
                     AVCAGDGVARPEVPDLVTRLVDRSLVVVVAGPTGPRYRLLESVAAYATERLHEMEDLAD
                     VRDRHLRHYLALAERAGPELRGAGQRSWLARLDAESGNLRAALDEAVRRAAAGTPAQAA
                     RLSTSLAWWWLLRGRLTQARRSLRAVLDVTTAANAESDEPELALLHAAFALLTGDHDMA
                     TAMPDGDAIPDPVRRARSLWLCAYGLFSAGAAADSGELNDRALTLFTSAGDQWGTAAAL
                     GLRATLALIRGDLAGLGRDGRHSAALFREVGDRWGELQTVSPLAALAEIKGEYEEAADR
                     QQEGLRMARELGLAAEVSARLSGLGRLALLARDWDRARDLHEQARRSAAEQGYKYGEIH
                     AGMGLALGARRTGDLDAAEAHLRHLRDGYADVSSPAGDHLVLAELGFVAELRGEADQAA
                     AHHLRGLEVARALGEPRALALSLEGLAGAAALHGTGPTASSAALLLGAADAARRSVGAP
                     LPSAERTDVDRITHAARTTLGDAAFTRAFDHGTRLAPEEALRQAAPVLGRLTREGG"
     gene            3656..4198
                     /locus_tag="M878_RS62025"
                     /old_locus_tag="M878_12995"
     CDS             3656..4198
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967607.1"
                     /locus_tag="M878_RS62025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_12995"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_023546608.1"
                     /transl_table=11
                     /translation="MTKYAGRTAVVVGDATGIGLAIAKRLVEGGAQVVLTARTAEERRR
                     LCAELGSTARVVAPSDVTACLGPGGEIDLLFAETVATARRLLSGLRDGGAVVLTAPGPP
                     SAAVHALATELVSRGIRVNAVAPGCIEAPGGSGAPLPPLGRLGAAEEVARAALFLATDA
                     TFTTGVRLPVDGGLSRP"
     gene            4293..5540
                     /locus_tag="M878_RS62030"
                     /old_locus_tag="M878_13000"
     CDS             4293..5540
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675890.1"
                     /locus_tag="M878_RS62030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13000"
                     /product="MFS transporter"
                     /protein_id="WP_023546609.1"
                     /transl_table=11
                     /translation="MSTTPDTAAGSAARTGAAARRPGVGEQPQKLPMFALLALATAVFI
                     TSLTETLPAGLLPAMSRDLHVSESATGQTVTIYAIGTALTAIPLTAVTAGWRRKRLLLT
                     AMAGFAVANTGTALSSLYGLTMAARCVAGVAAGLAWALLAGYARRLAPVHLQGRAIAIA
                     MAGIPVALSLGVPAGTFLGKVTDWRVAFLSMTALTVVLLAWIATAVPDFPGQERGERPK
                     MLHALRVPGVAPVLFVTLVFVLAHTIIYAYIATFLDDLGIGGNTDLVLLVFGAASLASI
                     WIVGAQIHHRLRVLTVASSLLVAVAAAVLAVLADHTALVYVAAVLWGLGWGGVPTLLQT
                     AAGDAGGESAADAAQAMLVTLWNVAMAGGGVIGGVLLDLSGSGSLPWSVLLLMLPVIAV
                     IVLARSHGFPAKRPAA"
     gene            5741..6589
                     /locus_tag="M878_RS62035"
                     /old_locus_tag="M878_13005"
     CDS             5741..6589
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (30-131). E-value:
                     4.2e-14. Score: 44.7. Matches aSDomain:
                     nrpspksdomains_M878_RS62035_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="M878_RS62035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13005"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_023546610.1"
                     /sec_met_domain="PF00561 (E-value: 2.6e-10, bitscore: 39.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-14, bitscore:
                     54.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEETGSNEKTEMPQSVQPLLHHVEFGSGTPVVLLHGYTIDHRLL
                     LPLEPVFAARRGWRRLYVDLPGSGRSPRLSGPVTAEAMGEAVLRFVDKAVGDEPFAVVG
                     ISYGGQLARYLVAERGPQVLGTALIAPLVKASGERVLPERQVLSRDEALLASLDPADRE
                     AFAGIALYQDDAGWRSFSDHVLPGIRAHHREDAAALLKAYLLKQIPERRFGVHDGSHVV
                     VTGRQDHMVGWRDQLELLEHYPRATYAVVDGAGHNVHLDQPDAVHGLLGNWLDTLAAQH
                     L"
     aSDomain        5831..6133
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS62035_Abhydrolase_1.1"
                     /evalue="4.20E-14"
                     /label="M878_RS62035_Abhydrolase_1.1"
                     /locus_tag="M878_RS62035"
                     /protein_end="131"
                     /protein_start="30"
                     /score="44.7"
                     /tool="antismash"
                     /translation="PVVLLHGYTIDHRLLLPLEPVFAARRGWRRLYVDLPGSGRSPRLS
                     GPVTAEAMGEAVLRFVDKAVGDEPFAVVGISYGGQLARYLVAERGPQVLGTALIAP"
     misc_feature    6667..6682
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.42"
                     /tool="antismash"
     misc_feature    6673..6686
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.15"
                     /tool="antismash"
     misc_feature    complement(6674..6687)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.85"
                     /tool="antismash"
     misc_feature    6674..6688
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.09"
                     /tool="antismash"
     misc_feature    complement(6675..6688)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.68"
                     /tool="antismash"
     misc_feature    complement(6841..6861)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            6936..8141
                     /locus_tag="M878_RS62040"
                     /old_locus_tag="M878_13010"
     CDS             6936..8141
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609631.1"
                     /locus_tag="M878_RS62040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13010"
                     /product="transposase"
                     /protein_id="WP_037730109.1"
                     /transl_table=11
                     /translation="MSSSETRAATADGARIQRFVEDIFRSLHRVEQRRWARAYLWALIH
                     GSGKKTPRRMARMGSLPSSAAHGLHQFINASPWEWQPVRRRLAQRVAAESVPYAWAVAE
                     LIIPKSGGHSVGVHRRVDPATGQPVNCQRAVGLFLAGDSHAFPVDWSLVLNGPWDWDRQ
                     RRRRTRIPEEEKERPVGARVLDYAADAVTLPRAAGLPWVLDLTRCDDAAGVLAGLARER
                     LDVVCEVDPGQVVLVGQHTPTVSTVGALMGIGHARQPHVMVRQTPDGRTKVVPIHAYAG
                     TVRLPQLAAGSDGAARTYRVLERPAPDGRLPARYWITSLTERPVDEVLSLVRGRTAALS
                     AVSGLQDRFGALDFEGRSFPGWHHHMTMASAAYVYQYLDGTSGSASLPPAPAATRLTRA
                     AS"
     misc_feature    7116..7118
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8188..8904
                     /locus_tag="M878_RS62045"
                     /old_locus_tag="M878_13015"
     CDS             8188..8904
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967610.1"
                     /locus_tag="M878_RS62045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13015"
                     /product="response regulator transcription factor"
                     /protein_id="WP_023546612.1"
                     /transl_table=11
                     /translation="MTNVLVVERNTSAAEAMERDLRRQGYTTRSVHTGARALRAYRDAD
                     LVLLSLELADIDGLEVCRSVRSGADTPLIAVTDHDDELERVLALRAGADDCVVKTWGFR
                     EIGARIEAVLRRYRRRTAATAKPISLRPLHIDPRRREVRLHDLLIPVTSKEFELLYTLA
                     VNPETVVSRKELMAKVWDSDWTSGSRTIDTHVSSLRAKLGCSRWITTVRGVGYRMGYGG
                     GRDPEMPETPKVLEAS"
     gene            complement(8976..9731)
                     /locus_tag="M878_RS62050"
                     /old_locus_tag="M878_13020"
     CDS             complement(8976..9731)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609633.1"
                     /locus_tag="M878_RS62050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13020"
                     /product="arylmalonate decarboxylase"
                     /protein_id="WP_031224788.1"
                     /transl_table=11
                     /translation="MDLFPLPRLGLVVPPENPTAEPEFTTLFGHHVNVYTTRFPVTPGL
                     GLRDMLEFYNRVLPDTLGQFGGMRLDGAVVACSASHYLLGPDGDLSFCAELSDRAGFPV
                     WSSTRATLAACEALGVRRLTLVSPYQPWLTDTSRAFWERAGLTVDGVVPVPARSAPGGD
                     RHYDPYQVTTEAILGHIAASELPGDTALLFTGTGMGTLAALEELARQEPGRTLLTSNLA
                     SVWWARRTLPGGDAGDEHALLRRLEKTAV"
     gene            10001..11152
                     /locus_tag="M878_RS62055"
                     /old_locus_tag="M878_13025"
     CDS             10001..11152
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947770.1"
                     /locus_tag="M878_RS62055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13025"
                     /product="isopropylmalate synthase"
                     /protein_id="WP_078630264.1"
                     /sec_met_domain="HMGL-like (E-value: 2.1e-50, bitscore:
                     170.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVENHEKLPVPPRISDATLRDSAHMAGVEFGPKDAAAIAGLLV
                     RTGVELVEVGMVSGPDSKDTPLVEAVHETVGPERSMTLLVVRDRQQVARALDEAERLGV
                     RHIMYSIPTSEQHAKLKLGSPSAKFLHALARSAIGQAKERGFHVTFSGEDGARTPRERL
                     VPYVTAGFEAGADRFRLAETVAYLSPWQMETVIADLTAIDDSEVEIHSHNMLGMAVANS
                     LAAVRAGARWISATVDGIGERGGNAPLAELLASLRVVHGDTRFDLTHLTELSRIALKGS
                     GLGEAFQAGPTTPHAFAYELPGQLSHPEAYETLPAELVGNARELRVRTRLAPALVTWAL
                     ADSGIFVDVDAFTAWLADRQEQAGGPLLDRDAIRKAAIDFQSS"
     gene            11199..11384
                     /locus_tag="M878_RS62060"
                     /old_locus_tag="M878_13030"
     CDS             11199..11384
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967615.1"
                     /locus_tag="M878_RS62060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13030"
                     /product="hypothetical protein"
                     /protein_id="WP_023546615.1"
                     /transl_table=11
                     /translation="MSTATLTGACPECETDLTVPPVVQGETLSCPECMLTLRVEDITDG
                     RLTLHMVEVQLRDWGQ"
     gene            11386..12234
                     /locus_tag="M878_RS62065"
                     /old_locus_tag="M878_13035"
     CDS             11386..12234
                     /GO_function="GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967616.1"
                     /locus_tag="M878_RS62065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13035"
                     /product="RimK family alpha-L-glutamate ligase"
                     /protein_id="WP_023546616.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.8e-09, bitscore:
                     36.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 3.4e-24, bitscore: 84.5,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 8.7e-09, bitscore:
                     34.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRKVAVVADRIGWEERQLIQRADELGLAIEWVNDESLCLGHLDA
                     PSVRNYDALLVRSRSYTRGGLVASLAEASGARTVNTARAIHACENKAALRTVLRTAGVP
                     VPDFRLVLSRRDFEQALAELELPVVLKPVFGGMGKRVTLIRHADTAQSVYDYVEDLGHA
                     FEQACLVEPYLGGTSVRCLVVGHELVGAAEFASGGTDWRNNAALGNDSRAVAHDPDVVK
                     IVDAVTAELGPGIYGVDLFRTADGYVVNEVNHAPGFRAVASATGADVASAIGRYLQELL
                     A"
     gene            12231..13286
                     /gene="argC"
                     /locus_tag="M878_RS62070"
                     /old_locus_tag="M878_13040"
     CDS             12231..13286
                     /EC_number="1.2.1.38"
                     /GO_function="GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379927.1"
                     /locus_tag="M878_RS62070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13040"
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="WP_023546617.1"
                     /transl_table=11
                     /translation="MIRAGVIGASGLAGGELIRLITQHPDLELTFLGGSSNIGRRPAQL
                     HPGLRIDTGLTVQPVTEDVADHVDVILLATPAPVSAELAALLADRVPAVVDLSGAFRIR
                     TPERHRRWYPKVERRADLADRFVYGVPELVGDQLADAALISLPGCYATAITLGLAPLTL
                     GLGLDLKTVVVDGKSGSSGGGLQLRTADLHPFRNGAIAPYAPTGHRHAAEVSDFLERSK
                     PGTLGSLSMSAYGVSHVRGLLTSAYVFTDGEVDQRTLQRAYLRFYKGHRFVRVRRHTET
                     LIPVPDPQAVLGSNYCDVTAMYDEEAGRIVVLAALDNLVKGAAGQAVQAVNLRFGLPEE
                     TGLTMHPVMPA"
     gene            13283..14089
                     /locus_tag="M878_RS62075"
                     /old_locus_tag="M878_13045"
     CDS             13283..14089
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1174: acetylglutamate kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947774.1"
                     /locus_tag="M878_RS62075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13045"
                     /product="acetylglutamate kinase"
                     /protein_id="WP_023546618.1"
                     /transl_table=11
                     /translation="MSPAHPPQEAPAVVKLGGSCLDDLDGAWWDDLARLGRRRPLVLVH
                     GWSKPLKKLSARSREPSAILRDRYGNQSRWTTPEVIDDIKTVSARLGSEVLQRLQRRGL
                     SAERLLGSDGLLAAGEAERWWWQGKQLVELENLVGPVTGADPTLLKDLEPGQARLVTPL
                     ARNASGREVNTDADRAAAALAGAVGAPDLVLVTDVGHLLIDGEPVHEIGAEAAAVFRDK
                     GATGGMRKKLRAAGEALERGVDRVVIGSAPVTELLAARTGTVITRT"
     gene            14101..14664
                     /locus_tag="M878_RS62080"
                     /old_locus_tag="M878_13050"
     CDS             14101..14664
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609639.1"
                     /locus_tag="M878_RS62080"
                     /note="Members of this family of hydrolases with an active
                     site Cys residue belong to MEROPS family C26.; Members of
                     this family of hydrolases with an active site Cys residue
                     belong to MEROPS family C26.; Members of this family of
                     hydrolases with an active site Cys residue belong to MEROPS
                     family C26; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13050"
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="WP_023546619.1"
                     /transl_table=11
                     /translation="MAQPRVLVVNNGTLSLPQLRRRFEELGAATDAVDAVSVPPRLDGR
                     YQAIVLSGTKVRAYDRDHYKPLVDLVMTADVPVFGICGGMQILAVSAGGRLAEGPQRVG
                     GYEVQVDKEEPLFTYVKPTVTVFHRHTLYLQEAPEGFRSIGRSAHAPVEFLRSDDGRIF
                     GSQAHLEFRSDGLEILRGFTQLYR"
     gene            14708..15826
                     /locus_tag="M878_RS62085"
                     /old_locus_tag="M878_13055"
     CDS             14708..15826
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379929.1"
                     /locus_tag="M878_RS62085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13055"
                     /product="Glu/Leu/Phe/Val dehydrogenase dimerization
                     domain-containing protein"
                     /protein_id="WP_037730110.1"
                     /transl_table=11
                     /translation="MSILEDTQEPAFTVHLNGSGGTIKGWVVVDTLVDGLAMGGVRMTP
                     GVTEEEVRGLARDMTDKFTLAGLRIGGAKGGIVSDGSNREETFHTFGRTVKPLLHGGIH
                     LGIDMGVTSADRAVFFTEAGYDPRYRLGAPDMPIDWRTYYEPLIDVTGHGVGVAAVTAL
                     EARGRTESARVVVQGFGTVGRAVARFLEDRGHVIVGVADIEGTVSADRLPVADLIAVTD
                     EFGRIDRSRLPQHVALSAEPDAWLDVDADLLVLAAQKYALTAENTHRLRAGLVVEGANL
                     ASSASAKEKVAASGGVLVPGVIANIGGAASAALAVTRVVPFGLAAEARKAWVFDWVGDR
                     VRQNTRDLLEIAVGRAGDPLPELLAARRKARR"
     gene            15868..17490
                     /locus_tag="M878_RS62090"
                     /old_locus_tag="M878_13060"
     CDS             15868..17490
                     /NRPS_PKS="Domain: AMP-binding (24-439). E-value: 4.3e-84.
                     Score: 274.4. Matches aSDomain:
                     nrpspksdomains_M878_RS62090_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489669.1"
                     /locus_tag="M878_RS62090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13060"
                     /product="AMP-binding protein"
                     /protein_id="WP_245238386.1"
                     /sec_met_domain="AMP-binding (E-value: 9.2e-83, bitscore:
                     277.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGAHADEFRRRGWWRDETFLDDLHRQARERPQRLAIAGRRIAEA
                     RTDTLDYAELARLTDRFALALLRLGVRRGDVVAVQLPNRWEMVPLMFACMRVGAVVCPI
                     SPICPKDELRHRLGLTEARVCVTLPEWSGTPLAEIITGLRAELPALGHVAVVGGPVPAG
                     AFSFHDHFVAEAREEVSGTAELDGLALSADDPFVVLFTSGTTGESKGVLHSQNTVHSAV
                     RGYVDAFGLGDDWVAAVSTPLVHYSGFAQGVLAGVMLGGTVAFQDVRRNEALLDLVERY
                     GATLLYGPPATLADVAASQRAEKRDTSTLRHVVIGSAPVLKELADEVHATLGARTYSLW
                     GMSENGPVTMTRPTDPEDWAVHSNGRAVDAMRTRIEAPGADGTGRLKVRGASLALGYYR
                     RDEAFAAEFDADGWFDTGDLAREDARGGIRIVGRARDAIVRDGEVAPMTELEAVIGSHP
                     RAVEAALVGLPPATDGADTVICAVVVPRGEQGPALDEVRARVRESGHDEHFLPDRMELV
                     PALPKTLTGKVRKAELRRRYGAG"
     aSDomain        15940..17184
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS62090_AMP-binding.1"
                     /evalue="4.30E-84"
                     /label="M878_RS62090_AMP-binding.1"
                     /locus_tag="M878_RS62090"
                     /protein_end="439"
                     /protein_start="24"
                     /score="274.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HRQARERPQRLAIAGRRIAEARTDTLDYAELARLTDRFALALLRL
                     GVRRGDVVAVQLPNRWEMVPLMFACMRVGAVVCPISPICPKDELRHRLGLTEARVCVTL
                     PEWSGTPLAEIITGLRAELPALGHVAVVGGPVPAGAFSFHDHFVAEAREEVSGTAELDG
                     LALSADDPFVVLFTSGTTGESKGVLHSQNTVHSAVRGYVDAFGLGDDWVAAVSTPLVHY
                     SGFAQGVLAGVMLGGTVAFQDVRRNEALLDLVERYGATLLYGPPATLADVAASQRAEKR
                     DTSTLRHVVIGSAPVLKELADEVHATLGARTYSLWGMSENGPVTMTRPTDPEDWAVHSN
                     GRAVDAMRTRIEAPGADGTGRLKVRGASLALGYYRRDEAFAAEFDADGWFDTGDLARED
                     ARGGIRIVGRARDAIV"
     CDS_motif       16459..16509
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS62090_0001"
                     /evalue="3.80E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="M878_RS62090"
                     /protein_end="214"
                     /protein_start="197"
                     /score="19.5"
                     /tool="antismash"
                     /translation="VLFTSGTTGESKGVLHS"
     CDS_motif       17017..17076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS62090_0002"
                     /evalue="3.30E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="M878_RS62090"
                     /protein_end="403"
                     /protein_start="383"
                     /score="10.0"
                     /tool="antismash"
                     /translation="GRLKVRGASLALGYYRRDEA"
     gene            17496..>17782
                     /locus_tag="M878_RS47700"
                     /pseudo=""
     CDS             17496..>17782
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS47700"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTAPRTATPRAAAVPMSATLAADAALVERRRTGQRVLPMTSGEI
                     GLPVHPALRERLAAAAGENAYGPVAGGPALREAAAGYWGRRGLPTDPGLV"
     assembly_gap    17783..18604
                     /estimated_length=822
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            <18605..19422
                     /locus_tag="M878_RS62095"
                     /old_locus_tag="M878_13075"
     CDS             <18609..19422
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (6-225). E-value: 2.7e-28.
                     Score: 91.1. Matches aSDomain:
                     nrpspksdomains_M878_RS62095_Aminotran_1_2.1"
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947778.1"
                     /locus_tag="M878_RS62095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13075"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_023546622.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.9e-26, bitscore:
                     91.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RAAGRDPRAVVVTVPDNPTGTVASAATVRGLAEAARDLDLVLVSD
                     EIYGDLVHDPDRAAVSPARYAPERTVVTTGLTKNLALGGWRTGVARLPDSPAGHELRTR
                     LVSVASQIWSSPPAPVQTAAAYAFAEPAEITGRIAASRRLHAAVVRAAAASFTAVGADL
                     APVTATCYLYPDFEPLRARLTEAHGVSGGEDIVRFLVERHGVGVLPASAFGEPGSALRI
                     RAATSRLYGDTDEQRTAALTAPDPLTLPWIRQSLTHLGEALADLTDPRP"
     aSDomain        18628..19284
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS62095_Aminotran_1_2.1"
                     /evalue="2.70E-28"
                     /label="M878_RS62095_Aminotran_1_2.1"
                     /locus_tag="M878_RS62095"
                     /protein_end="225"
                     /protein_start="6"
                     /score="91.1"
                     /tool="antismash"
                     /translation="PRAVVVTVPDNPTGTVASAATVRGLAEAARDLDLVLVSDEIYGDL
                     VHDPDRAAVSPARYAPERTVVTTGLTKNLALGGWRTGVARLPDSPAGHELRTRLVSVAS
                     QIWSSPPAPVQTAAAYAFAEPAEITGRIAASRRLHAAVVRAAAASFTAVGADLAPVTAT
                     CYLYPDFEPLRARLTEAHGVSGGEDIVRFLVERHGVGVLPASAFGEPGSALRIRAA"
     gene            19443..20372
                     /locus_tag="M878_RS62100"
                     /old_locus_tag="M878_13080"
     CDS             19443..20372
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379932.1"
                     /locus_tag="M878_RS62100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13080"
                     /product="hypothetical protein"
                     /protein_id="WP_023546623.1"
                     /transl_table=11
                     /translation="MSQSLPPVLTEVAYDGGRYVTFGRPEPGEPQTLHRVAEGALAAAF
                     TTTDGSPDAVRAALADDGETVAVSAGAPGVRPLVPLLPPASGSALLSGFMGTHKKKWGG
                     QSAPQDAEFTPPKWFFKGFGDWARLPGEPLTVPARPVALIEEPEVVLVYVNDADGTPHY
                     AGYTFGNDLCDIGLHRKDPGYNPYCKLCDTALAPWLFLGPPPRSATGRVTIVRDGATAW
                     EGSFDCGGDALYFRVRDMVDHLFSFPAVRRPGLVNYVLLGADEASFHDGFRIADGDRIG
                     IDVKSHGVTFENTVRYVSPAPAAALPAS"
     gene            20369..21757
                     /locus_tag="M878_RS62105"
                     /old_locus_tag="M878_13085"
     CDS             20369..21757
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103630.1"
                     /locus_tag="M878_RS62105"
                     /note="This protein belongs to a clade of FMN-dependent
                     monooxygenases, within a broader family of flavin-dependent
                     oxidoreductases, the luciferase-like monooxygenase (LMM)
                     family, some of whose members use coenzyme F420 rather than
                     FMN; Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="M878_13085"
                     /product="NtaA/DmoA family FMN-dependent monooxygenase"
                     /protein_id="WP_023546624.1"
                     /transl_table=11
                     /translation="MSGPPAAGRKQVHLAAQLPGIHNVTVWSDPRARSQIAFDSFLHLA
                     QTAERGRFDFFFLAEGLRLREHKGQLYDLDVVGRPDNLTQLSALAAVTTRLGLAATVNA
                     TFNEPYEVARRLATLDHLSAGRTAWNVVTSSDAFTGENFRRGGFLAEADRYARAAEFLA
                     TARELWDSWADGDVRADAVAGAYLRPGAGRFAHRGRHFDISGRFTTPRPPQGHPVIIQA
                     GDSDTGREFAAAEADVVFSKYNRLDQARSFYRDVKGRLARHGRTPDRLKILPTATVVVA
                     DSDAEAAAYADEITRAQVSPQTAIAHLEAVWGRDLSGYDPDGPLPDIDPDPDSLTLKGH
                     SLFRRGRAETARRWRALAERRGLSIRELVIEISGGQTFVGAPRTVADAIDHFVQTGGAD
                     GFVLVPHLTPTGLDDFVARVVPLLQEEGVFRPDYTSRTLRDHLGLPHDRGEDTADPAAE
                     EEAS"
     gene            21754..22977
                     /locus_tag="M878_RS62110"
                     /old_locus_tag="M878_13090"
     CDS             21754..22977
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526416.1"
                     /locus_tag="M878_RS62110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13090"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_023546625.1"
                     /transl_table=11
                     /translation="MTASPLHLAVALDGAGWHPAAWRAEDARPGALFTAQYWADLVTEA
                     EHGMLDFVTFEDALGIQSAAFHRPDDRTDQVRGSLDAVLLAARMAPLTTHIGLVPTANV
                     THTEPFHVATGIATLDHASKGRAGWRPQIAARAADATHFGRRTTPQLTDDDVRDPERIG
                     RRLRPLFDEATDVVEVARRLWDSWEDDAEIRDAATGRFIDRGKVHHIDFAGAHFGVRGP
                     SIIPRPPQGQPLVTSLAHAMVPYEFATRSCDVVYVTPHDRAGAAAIVAQVDEAAGRSGR
                     DMRAWPLLRFAELLVFLDAEPRAATHRKTHLDSLDGAELTSDAEVFTGTPGELADLLLD
                     WREAGLDGFRIRPGTLPHDLVQITRGLVPELQRRGAFRTAYDATTLRGHLCLARPNSRY
                     SQERQTRK"
     gene            22974..24125
                     /locus_tag="M878_RS62115"
                     /old_locus_tag="M878_13095"
     CDS             22974..24125
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="M878_RS62115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13095"
                     /product="acyltransferase"
                     /protein_id="WP_023546626.1"
                     /transl_table=11
                     /translation="MTVLTQARPAARQLTFIAATRLLPSFCILASHLSFEQVFKDRTVQ
                     ETYYRIFNPAGFNAVSFFIVLSGFILTWISAERPPDRGFRARRLLRILPVHFLTWAVIV
                     CAFAATFSATGLFATLTLLQGWFPDHGIYWAANAPAWTLSTELVLYAVFPTAYRFLVRR
                     GDQFLFGLLTGLIAVVVLLPLALQLLPDGTTFANAAFTERGHLVRVSEWKYWLVYVFPL
                     TRVLEALCGMVVCLLVSRGRWTRKVRVPTALLVSAVVVEELWAPVLFDLTALTIVPIAL
                     LIGALAAKEIGRWNAPGATENRAVARVSAYGKYTFGIYMYQWAFIMVCQRYVHPWGNSV
                     AGGVLLVIAFYALCVAVSMVSYRFVETPVNRFMKPAIAAYTKR"
     gene            24802..26001
                     /locus_tag="M878_RS62120"
                     /old_locus_tag="M878_13100"
     CDS             24802..26001
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010350007.1"
                     /locus_tag="M878_RS62120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_13100"
                     /product="hypothetical protein"
                     /protein_id="WP_245238084.1"
                     /transl_table=11
                     /translation="MLAALPQRAAFRRALGVGPGQRLIVVSSTWAPRSLFGGAAEPEAD
                     DLLPWLLSRLSAELPADEYRTVAVLHPNIWYGHGPGQVRAWLDNARRAGLDAIPPLDGW
                     QQALIAADCVLGDHSSVTYYAASIGIPVVLGSFPQQDLDPLSPVAALGRTAPRLVRRGS
                     LRAQIDQVIAAHDPGRYKELAEQTSSAPGESAALLRRLFYGLMELPEPDRHSALLDPLP
                     LPPYLPARRTAPVRVLVGGIGSHPPEVSVVRYAVAGAGPGPAVCADSAHTVVDEETRET
                     GRLGIADVVVRYAAGDDPRLGPPAAWTAEALDRYPYCGLAAYVDGPDRCVVRTRDGDLV
                     RLSAAAALDGRADLCDPAAYASALHAWLASGRSLERALPGITVRTGATAHRVAVEPLAP
                     "
     misc_feature    26157..26171
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    26204..26219
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    27223..27237
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
ORIGIN
        1 caggcccgct tcgatgcgcg gcctctcgcg ttacgccgag gacactgccg cgtcgcatag
       61 ggcgactcgg ccagggctgg ccgaccggca gggtctccat cgccgtcggc gctgagcggg
      121 tgcctcgcag tcggctggga cctgctagcc gccctcccgc gtgagtcgcc ccaggaccgg
      181 tgcggcctgg cgcagcgctt cctcgggggc caggcgagtg ccgtggtcga aggcccgtgt
      241 gaaggccgca tcacccaggg tggtgcgcgc cgcgtgggta atgcggtcga cgtcggtgcg
      301 ttcggccgag ggcaggggtg cacccacgct gcggcgagcc gcgtccgccg ccccgagcag
      361 gagggccgcc gagcttgcgg tgggcccggt gccgtgcagg gctgccgcgc cggccaggcc
      421 ttccagggac agcgcgagcg cgcgcggctc gccgagtgcg cgggccacct ccaggccgcg
      481 cagatggtgg gccgcagcct ggtcggcttc gcctcgcagt tcggcgacga agcccagctc
      541 ggccagcacc aggtggtcgc ccgccggcga ggacacgtcc gcgtagccgt cgcgcaggtg
      601 ccgcaggtgc gcctcggcgg cgtcgagatc gccggtacgg cgggcgccga gcgcgaggcc
      661 catcccggcg tggatctcgc cgtatttgta accctgttcg gcggcactgc gccgtgcctg
      721 ttcgtgcagg tcgcgggccc ggtcccagtc gcgggccagc agtgccaggc ggcccagacc
      781 ggacagccgg gccgacacct cggccgccag gcccagttcg cgcgccatcc gcagcccttc
      841 ctgctggcgg tccgcggcct cttcgtactc gcccttgatc tcggcgagcg cggcgagcgg
      901 cgacaccgtc tgcagttcgc cccagcggtc acccacctcg cggaagagcg cggcgctgtg
      961 cctcccgtcg cggcccagcc cggcgagatc gccgcggatc agtgcgagcg tggcccgcag
     1021 cccgagtgcg gccgcggtgc cccactggtc gcctgctgag gtgaacaggg tcagcgctcg
     1081 gtcgttcagc tcgccgctgt cggccgctgc tccggcgctg aacaggccgt acgcacacag
     1141 ccacagcgac cgcgcccggc gcaccgggtc gggaatggcg tcaccgtccg gcatcgcggt
     1201 agccatgtcg tgatcaccgg tgagcagtgc gaacgcggcg tgcagcagag ccagttcggg
     1261 ctcgtcggat tccgcgttcg cggccgtggt gacgtccagg accgcgcgca ggctccggcg
     1321 ggcctgggtg aggcggccgc gcagcagcca ccaccaggcc agggaggtgg acaggcgtgc
     1381 cgcctgggcc ggggtcccgg cggcagcccg gcgcaccgcc tcgtcgaggg ctgcccgcag
     1441 gttgccggac tcggcgtcga gccgggcgag ccaggagcgc tgccctgcgc cgcgcagttc
     1501 gggcccggcg cgttcggcga gtgcgaggta gtggcgcagg tgccggtcgc gtacgtcggc
     1561 gaggtcctcc atctcgtgca gccgttcggt cgcgtacgcg gcgacggact ccaggagccg
     1621 gtagcgtggg ccggtcggtc cggccacgac gaccaccagg gaccggtcga caagccgggt
     1681 caccaggtcg ggcacctcgg gacgggcgac cccgtcaccc gcgcacaccg cctccgccgc
     1741 ctggaggtcg cagccgtcgc tgaacgcggc catgcggcgc agcacgatgc gctcgggggc
     1801 gctgagcagt tcccagctcc agtcgatcat cgcgcgcagg gtttgctggc gctcgggcgc
     1861 gccgcgccgc cccgaggtca ggagctggaa ccggtcgccg agccgggccg ccagctcgcg
     1921 tacgccaagg gcgcgcacgc gggtcgcggc cagttccagg gcgagcggga tgccgtccaa
     1981 gcggcggcag atctccgtga cggcggtgcg gtcggagccg gcgccgccgt ccgaggccag
     2041 tgagaagccg ggcgcggcag cagcggcgcg ctcggtgaac agccgtaccg cgtcggcggt
     2101 gggcagcggc tccaccagga acacctcctc gcccggcagg ccgagtggct cctggctggt
     2161 agcgagcacg cgcaggccgg gcgcggtgcg caggagcagg gcggcgagtt cggcggcggc
     2221 gtcgacgacg tgctcgcagt tgtccaggac gagcagtgtg cgacggtcgc gcagcactgc
     2281 ggcgaggtga tgcgcgggcg accgggtgcc ggtgccggag accggcaggg cggagggcgc
     2341 gtggtcgctg atgcccaggg ccgcggtgac gacctgcgcg aggtcggcgg cagtcccgtg
     2401 gcgtatgccg gagaactcca cgaaccaggt tccgtcgggc agaacctcgg cggacccgcc
     2461 gctgtggacc gcgtcggctg ccgccacggc cagtcgggtc ttgcccactc cgccggcgcc
     2521 ggtgagggtc accaggcgtg tggcgcgcag gagtgcagcg aggtgggcga gggccttgtc
     2581 gcggccgatg aggggggtca gggaggcggg caggttggag ggcgcgcgtg agacgtgcgc
     2641 gttcgcctcc gcgggaggac gagggctgat ggcgtcccgc tccgtacgag gacgagggcg
     2701 gtcggtgttc catggcgtcc ccgtcagctc cggggcctgg cggagcacgg cctggtgcag
     2761 agcagcgagt tcggggctcg gctcgacgcc caggtctgcg atgagacacg cacgcagatc
     2821 ctcatacgcc gcgagcgcct cgctctgccg ccccgccgtg tacaacgccc gcatctgcag
     2881 cgcgcgcagc cgttcccgga ggggatgccg ggccaccagg tcggcgagct ccccggcgag
     2941 gagcacctgg tcgccggccg ccaggcgggc ctcggcctgt tcttccagta cggacagccg
     3001 ctgctcggtg agacgctgca cggccccgcg gacgaactcc tggtcggcga agtcggcgta
     3061 ggcgggcccg cgccacagct caagtgcctc ggtgagcagc gcggctcggg cgctcggggc
     3121 cgcgacgtca cgcgcccggt ccaccaggcc gcggaaccgg acggcgtcca cctcatcgtg
     3181 gtcgctgtcg agacgcagcc gatagccggc cggctggtgc accacgcggt cccggcccag
     3241 gacccggcgt agttgcgaga ccttggcctg cagcgcgccc gcaggccggc ccggcgggct
     3301 gtcgccccac aggtcgtgga tgaggcggtc cgcggagacc gggccgccgt catgcgcgag
     3361 caggtcggcg agcagcgtcc ggaccttcgc ctcgggaacc ctgacggcca ccccctcgtc
     3421 gtcccacacc gccagtgggc cgagcacccc aaaccgcatg tgcgtcactg tacgtcacgg
     3481 agccgttccg gcggggtggg gaccgaggcc gtcggcagcc ctcgccgtcc cagccgtaag
     3541 ccggccgtca gccgttccga aggtttcccg aagcggcccg gcgcacagtc gtgtccgccg
     3601 ggccactcca cgtgcccccg gcacaagagg caggcgcggg ggagggagcg gcagcatgac
     3661 caagtacgcg ggccggacgg ccgttgtcgt cggagacgcc accggaatcg ggctggccat
     3721 cgccaagcgc ctggtcgaag gcggcgccca ggtcgtactg accgcccgca ccgccgagga
     3781 gcgccgccgc ttgtgcgccg aactgggctc caccgcccgg gtcgttgcac cgtccgacgt
     3841 gacggcctgc ctcggtcccg gcggcgagat cgacctgctg ttcgccgaga cagtggccac
     3901 cgcccgacgg ctgctgtccg gcctcaggga cggcggggcg gtcgtgctca cggcgcccgg
     3961 cccgccgtcc gccgccgtgc atgcgctggc caccgagctc gtctcccgcg gtatccgcgt
     4021 caacgccgtg gcgccggggt gtatcgaggc tccgggcggc agcggtgcgc ctctgccacc
     4081 gctgggccgc ctcggtgccg ccgaggaggt cgcccgggcc gcactcttcc tcgccacaga
     4141 cgccacgttc accaccggcg tccgcctccc ggtcgacggc ggcctcagcc ggccatgacg
     4201 ccgtaccagc cgcacacgac tgcccgcccc accccaccga ggcggacccg ggcgttcacc
     4261 caccccgtcc ccgacacccc tggagcacac tcatgagcac cacacccgac accgcggccg
     4321 gctcggccgc gcggaccggc gccgcagcgc gccgaccggg cgtcggcgag cagccgcaga
     4381 aactgcccat gttcgccctg ctggccctcg cgaccgccgt cttcatcacg agtctgaccg
     4441 agaccctgcc cgccggtctg ctcccggcga tgagccggga tctgcacgtg agtgagtccg
     4501 cgaccggcca gacggtcacg atctacgcga tcggcaccgc gctcaccgcg atcccgctga
     4561 ccgcggtcac cgccggctgg cgccgcaagc ggctcctgct gacggccatg gcggggttcg
     4621 ccgtggccaa taccggcacc gcgctgtcct ccctctacgg gctgacgatg gcggcgcgct
     4681 gtgtcgcggg cgtcgcggcc ggcctggcct gggcgctcct cgccgggtac gcccgccgac
     4741 tcgccccggt ccatctccag ggccgggcga tcgccatcgc gatggcgggc attccggtcg
     4801 cgctctcgct cggcgtgccc gccggcacct tcctcggcaa ggtgaccgac tggcgcgtgg
     4861 ccttcctctc gatgacggct ctgaccgtgg tgctgctggc gtggatcgcc acggccgtac
     4921 cggacttccc gggccaggag cgcggcgagc ggccgaagat gctgcatgct ctgcgcgtcc
     4981 cgggcgtggc gccggtgctg ttcgtcacac tggtcttcgt cctggcgcac accatcatct
     5041 acgcgtacat cgccacgttc ctcgacgacc tcggcatcgg cgggaacacc gacctggtgc
     5101 tgctcgtgtt cggcgccgcc tcgctggcga gcatctggat cgtcggggcg cagatccacc
     5161 accggctgcg ggtgctgacc gtcgccagct cgctgctggt cgcggtggcc gccgcggtgc
     5221 tggccgtgct ggccgaccac accgcactcg tctacgtcgc cgccgtgctg tggggcctgg
     5281 gctggggcgg cgtgcccacc ctgctgcaga ccgcggccgg tgacgcgggc ggcgagtcgg
     5341 cggccgacgc ggcccaggcc atgctggtca cgctctggaa cgtcgcgatg gcgggcggcg
     5401 gcgtgatcgg tggcgtgctg ctcgacctga gcggcagcgg ctccctgccg tggagcgtgc
     5461 tgctgctcat gctgccggtg atcgccgtga tcgtgctcgc ccgcagccac ggcttcccgg
     5521 ccaagaggcc ggcggcgtag gcgacatcgg gcggcgtcga gaagggcgcg aaagggccac
     5581 gaggaattcg tatgcgcatc ggagagctgt cgcggcgtac ccacacctcc cgcggaccac
     5641 cggattccct tccggtccgt cccacggcgg gggctgccaa ccagccctcc tgccttgcaa
     5701 tttgaccatc acatcagtgt cagcatcgga ctgtggagcc atgaccgaag agactggatc
     5761 gaacgagaag accgagatgc cgcaatcggt gcagccgctg ctgcaccacg tcgagttcgg
     5821 ctccggcacg cccgtggtgc tgctgcacgg ctacaccatc gaccaccggc tcctgctgcc
     5881 cctggaaccc gtgttcgccg cgcgtcgcgg ctggcggcgg ctctacgtcg acctgcccgg
     5941 ctccggccgc tcgccgcgcc tgagcggtcc ggtgacggcc gaggccatgg gtgaggcggt
     6001 cctgcggttc gtggacaagg ccgtcggcga cgagccgttc gcggtcgtgg gcatctccta
     6061 cggcggccag ctcgcccgct acctggtagc cgagcgcggc ccgcaggtcc tgggcacggc
     6121 actgatcgcg ccgctggtca aggcgagcgg tgagcgcgtg ctgcccgagc ggcaggtgct
     6181 cagccgggac gaggcgctgc tggcctcgct cgacccggcc gaccgcgaag cgttcgccgg
     6241 catcgcgctg taccaggacg acgcgggctg gaggtccttc agcgaccacg tgctgcccgg
     6301 catccgtgcc caccaccgag aggacgccgc cgcgctgctc aaggcctacc tgctcaagca
     6361 gatcccggag cgccgcttcg gggtccacga cggcagccat gtcgtggtga ccggccgtca
     6421 ggaccacatg gtcggctggc gggaccagtt ggagcttttg gagcactatc cgcgcgcgac
     6481 ctacgcggtc gtcgacggtg caggccacaa cgtccacctc gaccaaccgg acgctgtgca
     6541 cggcctgctg ggcaactggc tcgacacgct ggcagcgcaa cacctctgaa cgggctgccc
     6601 gtcggcccat gaaccgaccg ccgaaggtat cccctggcct tcggcggtca ccgctgttct
     6661 ttccgcttcg cgatttgttc ataaaacttt gacaggccgt cgtctcactc ggatcggcgc
     6721 atcagtattg agccatgcag ggatttccgg ctcctggccc gcacccacga cccaggccgt
     6781 cccaccacgt ttgcccagct cagcgcgcga agtggcaaag tactcgcagc tcggcagacg
     6841 tgattgtcac tccggcggta ttttgttgcg tgtgcatatg cacgatgcgc cgacctcggt
     6901 gcaagcgtta cgaaatacga ggggacgtag cgtttatgtc gtcgagtgag acgcgcgcgg
     6961 caacggccga cggcgcgcga atacagaggt tcgtcgagga catcttccga tcgcttcacc
     7021 gagtggaaca acgccgctgg gcccgagcgt atctatgggc cttgatccac ggatccggca
     7081 agaagacacc gcggcgcatg gcgcgcatgg gttccttacc ctcatcggca gcgcacgggc
     7141 tgcaccagtt catcaacgcc agcccctggg aatggcagcc ggtgcgccgc cggctcgccc
     7201 agcgggtcgc cgcggaatcg gtgccctacg cgtgggcggt cgccgaactc atcatcccga
     7261 agagcggcgg gcactcagtg ggcgtgcacc gacgcgtgga ccccgcgacc ggacagcctg
     7321 tcaattgcca gcgcgcagtc ggactcttcc tggccggcga cagccatgcc ttcccggtcg
     7381 actggagcct ggtgctcaac ggcccctggg actgggaccg gcagcgcagg cgccgtaccc
     7441 ggataccgga agaggagaag gagcgaccgg tcggcgcccg cgtcctcgac tatgccgcgg
     7501 acgcggtcac cctgccgcgc gcggccgggc tgccctgggt cctcgacctg acccggtgcg
     7561 acgatgcggc cggcgtgctc gcggggctgg cgcgggagcg gctggacgtg gtgtgcgagg
     7621 tcgaccccgg acaggtcgtg ctcgtcggac agcacacgcc gaccgtgagc acggtgggcg
     7681 cgctgatggg gatcggacac gcccggcagc cgcatgtgat ggtgcggcag actccggacg
     7741 gccgcaccaa ggtggttccg attcacgctt atgccggcac ggtgcgattg ccgcagctgg
     7801 cggcggggtc cgacggcgcc gctcgcacct accgggtcct ggagcggccc gccccggacg
     7861 gacggctgcc tgcccggtac tggatcacca gcctcaccga acggccggtg gacgaggtgc
     7921 tgtccctggt gcggggccgc accgccgccc tgtcggccgt ctccggcctg caggatcgct
     7981 tcggcgccct ggatttcgag ggccgctcct tcccgggctg gcaccaccac atgacgatgg
     8041 cctcagccgc atacgtctac cagtacctcg acggcacatc aggcagcgcc tcgctcccgc
     8101 cggcgcccgc cgcgacccga ctgaccaggg ccgcgagctg acggcagccg agggagcgga
     8161 gaagccgatg aagagaggac ggcaggggtg acgaacgtac tcgtggtgga gcggaacacc
     8221 tccgcggccg aggccatgga acgcgatctg cgcagacagg gctacaccac gcggagcgtg
     8281 cacaccgggg cgcgggcgct gcgcgcatac cgcgacgcgg acctggtgct gctctcgctg
     8341 gagctcgcgg acatcgacgg cctggaggtg tgccggtcgg tgcgcagtgg tgcggacacc
     8401 ccgctgatcg ccgtgaccga ccacgacgac gaattggaac gggtcctcgc gctgcgcgcc
     8461 ggggcggacg actgtgtggt gaagacctgg ggtttccggg agatcggtgc gcggatagag
     8521 gccgtgcttc gccgttaccg ccgcaggacg gcggccacgg cgaagcccat atccctgcgc
     8581 ccgctgcaca tagatccacg caggcgggaa gtacggctgc acgacctgct gattcccgtc
     8641 acgtcgaagg aattcgagct gctctacacg ctggccgtga atcccgaaac ggtcgtgtcg
     8701 cgaaaggagt tgatggcgaa ggtgtgggac agcgactgga ccagcggcag ccgcaccatc
     8761 gacacgcatg tgagcagcct gcgggcgaaa ctcggctgca gccggtggat caccacggtc
     8821 cgcggtgtcg gctaccgaat gggatacggc ggaggccgcg accctgagat gccggagacg
     8881 cccaaggtac tcgaggcctc ataggccgcc ggaagccggg cgagcgcgag ggccccggcg
     8941 tgcgccgatg cgcgtacacc ggggccctcc gcgcgtcaca ccgccgtctt ctccagtcgc
     9001 cgcagcagcg cgtgctcgtc gcccgcgtcg ccgccgggca gcgtgcgccg ggcccaccag
     9061 accgacgcca ggttggacgt gagcagcgtg cggcccggct cctgccgggc cagttcctcg
     9121 agcgcggcga gcgtgcccat gcccgtgccg gtgaacagca gggcggtgtc gccggggagt
     9181 tcgctcgccg cgatgtgtcc gagtatggcc tcggtcgtca cctggtacgg gtcgtagtgc
     9241 cggtcgccgc cgggcgccga gcgcgccggg accggcacca cgccgtcgac cgtgaggccg
     9301 gcccgctccc agaaggcgcg cgaggtgtcc gtgagccacg gctggtacgg cgagacgagg
     9361 gtcagccggc gcacgcccag ggcctcgcac gcggccaggg tcgcccgcgt cgaggaccac
     9421 accgggaagc ctgcccggtc ggacagctcg gcgcagaagg agaggtcgcc gtccgggccc
     9481 agcaggtagt gcgaggcact gcacgccacc acggccccgt ccagccgcat gccgccgaac
     9541 tgaccgagcg tgtcgggcag aacgcggttg tagaactcca gcatgtccct gaggccgagt
     9601 cccggtgtca ccgggaagcg agtcgtgtac acgttcacgt ggtgcccgaa cagggtggtg
     9661 aactccggtt cggcggtggg gttctccggt ggtacgacga gcccgagccg aggcagtggg
     9721 aaaaggtcca tgaacggcac ggtaggcgca gtacgactgc ccggccgccg cattccgtcc
     9781 actttttcgt acggccgaca ccgttctcgc actgcctgtc gttcctgaca ttccctgaca
     9841 cttttccacc gtcttctgac gcggaagtca ttgcttggaa tcgctcgcag cacggaggct
     9901 gttggtcgac gccagccgca tccgttcccg gattgcggtt caccgaactc gtccggaagc
     9961 aggaaccgca tttccgttcc ggaacaagga gtgaactgaa atggcaccag tggagaacca
    10021 cgagaaactc ccggtccccc cgcgaatatc cgacgcgacc ctgcgcgact ccgcgcacat
    10081 ggcgggcgtc gagttcggcc cgaaggacgc ggcggccatc gccggtctgc tggtgcgaac
    10141 cggcgtcgaa ctggtcgagg tgggcatggt ctccggcccg gactccaagg acacccccct
    10201 ggtcgaggcc gtgcacgaga ccgtcggccc cgagcgcagc atgacgctcc tcgtggtacg
    10261 tgaccggcag caggtggccc gggccctgga cgaggcagag cgcctgggtg tgcgccacat
    10321 catgtactcc atccccacct cggagcagca cgcgaagctg aagctgggtt cgccaagcgc
    10381 caagttcctg catgcgctgg cccgttcggc gatcggacag gccaaggaac gcggcttcca
    10441 cgtcaccttc agcggcgagg acggggcccg cacccccagg gagcggctcg tcccgtatgt
    10501 caccgccggc ttcgaggcgg gggccgaccg gttccggctc gccgagaccg tcgcctacct
    10561 ctcgccctgg cagatggaga cggtgatcgc cgacctcacc gcgatcgacg actccgaggt
    10621 cgagatccac tcgcacaaca tgctgggcat ggccgtcgcc aactcactcg ccgccgtccg
    10681 cgccggggca cgctggatct cggcgaccgt cgacggcatc ggcgagcgcg gaggcaacgc
    10741 ccccttggcc gaactgctgg cctcgctgcg ggtcgtgcac ggcgacaccc gcttcgacct
    10801 cacccacctc accgagctgt cccgcatcgc cctcaaaggc tctggcctcg gcgaagcctt
    10861 ccaggccggc ccgaccacgc cgcacgcctt cgcctatgag ctgcccggcc agctcagcca
    10921 cccggaggcc tacgaaacgc tgcccgccga actggtcggc aacgcccgcg agctgcgggt
    10981 acgcacccgg ctggccccgg ccctcgtcac gtgggcactg gccgactccg ggatcttcgt
    11041 cgacgtcgac gccttcacgg cctggctcgc cgaccgccag gagcaggccg gcggcccgct
    11101 cctggaccgg gacgcgatcc gcaaggccgc gatcgacttc cagtcctcct gaacgccctc
    11161 cacagcccac ccattccagt acaaggacgg agctccccat gtccaccgcc accctcaccg
    11221 gcgcctgccc ggaatgcgag accgacctga ccgtgccgcc ggtcgtccag ggcgagacgc
    11281 tctcctgccc agagtgcatg ctcacactgc gtgtcgagga catcacggac gggcggctga
    11341 ccctgcacat ggtcgaggtt cagctgcgcg actggggcca gtgagatggg ccgcaaagtc
    11401 gccgtcgtag ccgaccggat cggctgggag gagcgtcagc tgatccagcg ggccgatgag
    11461 ctcgggctcg ccatcgagtg ggtcaacgac gagtccctgt gcctcggcca cctcgacgcc
    11521 ccgtccgtcc ggaactacga cgccctgctg gtgcgcagcc gcagctacac ccgtggtggc
    11581 ctggtcgcga gcctcgccga ggcctcagga gcccgcaccg tcaacaccgc ccgggcgata
    11641 cacgcctgcg agaacaaggc cgcgctgcgc accgtgctgc gcaccgccgg cgtcccggtg
    11701 ccggacttcc ggctcgtgct gtcccgcagg gacttcgagc aggcgctcgc cgaactggaa
    11761 ctgccggtgg tcctcaagcc ggtcttcggc ggcatgggca agcgggtcac gctgatccgg
    11821 cacgccgaca ccgcccagtc cgtgtacgac tacgtcgagg acctcggtca cgccttcgag
    11881 caggcttgcc tggtcgagcc gtacctgggc ggaacctcgg tgcgctgcct ggtcgtcggc
    11941 cacgaactgg tcggcgccgc ggagttcgcc agcggtggca cggactggcg caacaacgcc
    12001 gcactcggca acgacagccg cgcagtcgcc cacgaccccg acgtcgtgaa gatcgtcgac
    12061 gccgtgacgg cggaactggg ccccggcatc tacggagtag atctgttccg caccgccgac
    12121 ggctacgtcg tcaacgaggt caaccacgcc cccggcttcc gggccgtggc ctcggccacc
    12181 ggcgcggacg tcgcctctgc catcggccgc tacctgcagg agctgctcgc atgatccgtg
    12241 caggagtcat cggcgcctcc gggctggccg gcggcgaact catcaggctg atcacccagc
    12301 atcccgacct ggagctgacc ttcctcgggg gctcctcgaa catcggcagg cgcccggccc
    12361 aactgcaccc gggcctgcgc atcgacaccg gcctgaccgt acagccggtc accgaggacg
    12421 tcgccgacca cgtcgacgtc atcctgctgg ccacccccgc gccggtctcc gccgagctgg
    12481 ccgcgctgct cgcggaccgc gtcccggccg tcgtcgacct gagcggcgcc ttccgcatcc
    12541 gcaccccgga gcggcacagg cgctggtacc cgaaggtcga gcggcgcgcc gacctggccg
    12601 accggttcgt ctacggcgtt ccggagctgg tgggtgacca gctggccgac gcggcgctca
    12661 tctcgctgcc cggctgctac gccaccgcga tcacgctcgg cctcgccccg ctcactctcg
    12721 gcctcggcct ggatctgaag accgtagtgg tggacggcaa gagcggctcc agcggcggcg
    12781 gcctgcaact gcgcaccgcc gacctgcatc ccttccgcaa cggcgccatc gcaccgtacg
    12841 cgcccaccgg tcaccggcat gcggcggagg tcagcgactt cctggagcgc agcaagccgg
    12901 gcacgctcgg ctcgctgagc atgtcggcgt acggcgtctc gcacgtgcgc gggctgctca
    12961 ccagtgctta cgtgttcacc gacggcgagg tcgaccagcg cacgctccaa cgggcgtacc
    13021 tgcgcttcta caaggggcac cggttcgtgc gggtgcggcg gcacaccgag acgctgatcc
    13081 cggtgccgga cccgcaggcg gtgctcggct ccaactactg cgatgtgacg gcgatgtacg
    13141 acgaggaggc cggccggatc gtcgtcctcg ccgccctcga caacctggtc aagggcgcgg
    13201 ccggccaggc cgtacaggcg gtgaacctcc ggttcgggct gcccgaggag acgggcctga
    13261 ccatgcaccc ggtgatgccc gcatgagccc ggcgcatccc ccgcaggagg ccccggccgt
    13321 cgtgaaactc ggcggcagct gcctcgacga cctcgacggt gcctggtggg acgacctggc
    13381 ccggctgggc cggcggcgtc cgctcgtcct ggtgcacggc tggtccaagc cgctgaagaa
    13441 gctcagcgcc cgctcccgag agccgtcggc gatcctgcgc gaccggtacg gcaaccagag
    13501 ccgctggacc acgcccgagg tcatcgacga catcaagacc gtcagcgccc ggctcggcag
    13561 cgaggtgctg cagcggcttc agcggcgcgg cttgagcgcc gagcggctgc tcggcagcga
    13621 tggactgctc gccgcgggcg aggcggagcg ctggtggtgg cagggcaagc agctggtcga
    13681 gctggagaac ctggtcggcc cggtcaccgg cgcggacccg accctgctca aggacctgga
    13741 gcccggccag gccaggctcg tcaccccgct ggcccgcaac gcctcgggcc gggaggtcaa
    13801 caccgacgcc gaccgggccg ccgccgctct cgccggcgcc gtcggcgcac ccgatctcgt
    13861 gctcgtgacc gatgtcggtc atctgctgat cgacggcgag ccggtgcatg agatcggcgc
    13921 cgaggccgct gccgtgttcc gcgacaaggg cgccaccggc ggcatgcgca agaagctgcg
    13981 ggccgccggc gaagccctgg agcggggcgt ggaccgggtc gtcatcggca gtgcgcccgt
    14041 caccgagttg ctcgctgccc gtaccggcac cgtcatcacg cgaacgtgag gagtacgcac
    14101 gtggcgcagc cccgtgtcct ggtcgtcaac aacggaacgc tgtccctgcc ccaactgcgc
    14161 cgccgcttcg aggagctggg cgcggccacc gacgcggtcg acgcggtgtc cgtgccgcct
    14221 cgcctcgacg gccgctacca ggcgatcgtg ctgagcggca ccaaggtgcg ggcctacgac
    14281 cgcgaccact acaagccgct cgtcgatctc gtcatgaccg ccgacgtgcc ggtcttcggg
    14341 atctgcggcg gcatgcagat cctggcggtc tcggccggcg gccggctcgc cgagggcccc
    14401 cagcgggtcg gcggctacga ggtgcaggtc gacaaggaag agcccctgtt cacctacgtc
    14461 aaaccgacgg tgacggtgtt ccaccggcac accctctatc tccaggaggc cccggagggc
    14521 ttccgctcca tcggccgctc cgcgcacgcg cccgtcgagt tcctgcgctc cgacgacgga
    14581 cgcatcttcg gttcccaggc gcatctggag ttccgcagcg acggcctgga gatcctgcgg
    14641 ggcttcacgc agctctaccg gtgaccaccg cctgttcacc tactcacccg aggacttgag
    14701 aatcgccatg agcattttgg aagacacgca agagcctgcg ttcaccgtcc acctgaacgg
    14761 cagcggcggc accatcaagg gctgggtggt cgtcgacacg ctggtcgacg gcctcgccat
    14821 gggcggggta cggatgacgc cgggggtcac cgaggaggag gtccgcggcc tggcccgcga
    14881 catgaccgac aagttcaccc tcgcggggct gcgcatcggc ggtgccaagg gcggcatcgt
    14941 ctccgacggc agcaaccgcg aggagacctt ccacaccttc ggccgcaccg tcaagcccct
    15001 gctgcacggc ggcatccacc tcggcatcga catgggcgtc acctccgccg accgcgccgt
    15061 cttcttcacc gaggccggct acgacccgcg ctaccggctg ggtgccccgg acatgccgat
    15121 cgactggcgc acctactacg agcccctgat cgacgtcacc ggacacggcg tcggggtggc
    15181 cgcggtcacc gccctggagg cgcgcgggcg taccgagtcg gcccgggtcg tggtgcaggg
    15241 cttcggcacg gtgggtcgcg cggtcgcgcg gttcctggag gaccgcgggc atgtgatcgt
    15301 gggcgtcgcc gacatcgagg gcaccgtcag cgccgaccgg ctgccggtgg ccgacctgat
    15361 cgccgtcacc gacgagttcg ggcggatcga ccgctcccgc ctgccgcagc acgtcgctct
    15421 ctccgccgag ccggacgcct ggctcgacgt cgacgccgat ctgctggtcc tcgcggcaca
    15481 gaagtacgcc ctcaccgccg agaacaccca ccgcctgcgc gccggccttg tcgtcgaggg
    15541 ggccaacctc gcctccagcg cctcggccaa ggagaaggtg gccgcttcgg gtggcgtcct
    15601 ggtgccgggc gtgatcgcca acatcggcgg ggccgcgtcc gccgccctgg ccgtcacccg
    15661 ggtcgtgccc ttcggcctgg cggcggaggc gcgcaaggcg tgggtgttcg actgggtcgg
    15721 cgaccgagtg cggcagaaca cccgggacct gctggagatc gcggtcggcc gggcgggcga
    15781 cccgctgccg gagctgctcg cggcccgccg gaaggctcgc cggtgaacgc cccggctaag
    15841 gccgcacgcc ccggcgcagc cgccgcggtg tccggcgcac acgccgacga gttccggcgc
    15901 cgtggctggt ggcgcgacga gaccttcctc gacgacctgc accgccaggc gcgcgagcgc
    15961 ccgcagcggc tggcgatcgc cgggcgccgg atcgccgagg cgcgcaccga cacgctggac
    16021 tacgccgaac tggcccggct caccgaccgg ttcgcgctcg cgctgctccg gctcggcgtg
    16081 cgcagaggcg acgtcgtcgc cgtacagctg cccaaccggt gggagatggt gccgctgatg
    16141 ttcgcgtgca tgcgcgtcgg cgccgtcgtc tgtccgatct cgccgatctg cccgaaggac
    16201 gagctgcggc atcgcctcgg actgaccgag gcccgggtgt gcgtcacgct ccccgagtgg
    16261 tcgggcacac cgctggcgga gatcatcacc gggctgcggg ccgagctgcc ggcgttgggc
    16321 cacgtcgcgg tggtgggcgg cccggtgccg gccggcgcgt tctccttcca cgatcacttc
    16381 gtggccgagg ctcgcgaaga ggtttccggc accgccgagt tggacggtct ggcgctgagc
    16441 gccgacgacc cgttcgtggt gctgttcacc tccgggacca cgggcgagtc caagggcgta
    16501 ctgcacagcc agaacaccgt ccactccgcc gtgcgcggct acgtcgacgc cttcggactc
    16561 ggcgacgact gggtggcggc ggtctccacg ccgctcgtgc actactccgg cttcgcccag
    16621 ggcgtcctcg cgggcgtcat gctcggcggc accgtcgcct tccaggacgt ccgcaggaac
    16681 gaggcgctgc tggacctggt ggagcgctac ggcgccacac tgctgtacgg gccgccggcc
    16741 acgctcgccg acgtcgccgc ctcgcagcga gcggagaagc gggacacgag cacgctgcgg
    16801 cacgtggtca tcggctcggc gccggtcctc aaggagctcg ccgacgaggt gcacgcgacg
    16861 ctcggcgcgc ggacctactc gctgtggggc atgtcggaga acggcccggt caccatgacc
    16921 cggcccaccg accccgagga ctgggccgtg cacagcaacg gccgggccgt cgacgccatg
    16981 cggacccgca tcgaggcacc cggcgcggac ggcacgggcc gcctgaaggt gcgcggcgcc
    17041 tccctcgcgc tcggctacta ccggcgcgac gaggccttcg ccgccgagtt cgacgcggac
    17101 ggctggttcg acaccggcga cctggcccgg gaggacgccc gaggcggcat ccgtatcgtc
    17161 ggccgggccc gcgacgccat cgtccgggac ggggaggtcg cgcccatgac ggagctggag
    17221 gcggtcatcg gcagccaccc cagggccgtc gaggcggcgc tggtcggcct gccgcccgcg
    17281 accgacggcg ccgacaccgt gatctgcgcg gtcgtggtgc cgcgcggcga gcagggcccg
    17341 gccctcgacg aggtccgcgc ccgggtccgg gagtccggac acgacgagca ctttctgccg
    17401 gaccgcatgg agctggtgcc cgcgctgccc aagaccctga ccggcaaggt ccgcaaggcc
    17461 gaactgcgcc ggcggtacgg ggcggggtga gccacgtgcg cacggccccc cggacggcca
    17521 cgccgcgagc cgccgccgtc cccatgtcgg cgacgctcgc cgctgacgcc gcccttgtcg
    17581 aacggcgccg cacgggacag cgcgtgctgc ccatgaccag cggcgagatc ggtctgcccg
    17641 tgcacccggc gctgcgcgag cggctggccg ccgcggccgg cgagaacgcc tacggcccgg
    17701 tggctggcgg ccccgcgctg cgcgaggccg ccgccggcta ctggggtcgg cgcggcctgc
    17761 ccaccgaccc cgggctcgtg gtnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18601 nnnncgcgcg ccgccgggcg ggacccgcgc gccgtggtgg tgacggtgcc ggacaacccg
    18661 accggcaccg tcgcctccgc cgcgaccgtg cggggcctgg ccgaggcagc ccgcgacctc
    18721 gacctcgtcc tggtctccga cgagatctac ggcgacctcg tccacgatcc cgaccgtgcc
    18781 gcggtctccc cggcgaggta tgcccccgag cgcacggtcg tcaccaccgg gctcaccaag
    18841 aacctggcgc tgggcggctg gcgcaccggc gtggcacggc tgcccgacag ccccgccgga
    18901 cacgagctgc gcacgcggct ggtctccgtc gccagccaga tctggtccag cccgccggcc
    18961 ccggtgcaga cggccgcggc ctacgccttc gccgagccgg cggagatcac cgggcggatc
    19021 gcggcgagcc ggcgactgca cgcggcggtg gtgcgtgcgg cagccgcgag cttcacagcg
    19081 gtcggcgcgg acctcgcgcc ggtgaccgcc acctgctacc tctacccgga cttcgagccg
    19141 ctgcgcgccc gcctcaccga ggcacatggc gtaagcggcg gcgaggacat cgtccggttc
    19201 ctcgtcgagc gccacggcgt cggcgtcctc ccggcgagcg cgttcggcga gccgggcagc
    19261 gcgctgcgga tccgtgccgc caccagccgc ctgtacggcg acaccgacga gcagcgcacc
    19321 gccgcgctga ccgctcccga cccgctcacc ctgccctgga tccgccagtc cctcacccac
    19381 ctcggcgagg ctctggcgga cctgaccgat ccccggccct gaccgcatct ggaggcttcc
    19441 gcatgtccca gtcactgccg cccgtcctca ccgaggtcgc ctacgacggc ggtcgttacg
    19501 tcaccttcgg ccggcccgag ccgggcgaac cgcagacgct gcaccgggtc gccgagggcg
    19561 ccctggccgc cgcgttcacc accaccgacg gctccccgga cgccgtccgg gccgcccttg
    19621 ccgacgacgg cgagaccgtc gcagtcagcg ccggggcccc gggggtgcgc ccgctggttc
    19681 cgctgctgcc cccggcgtcc ggctccgcgc tgctcagcgg cttcatgggc acgcacaaga
    19741 agaagtgggg cggacagagt gccccgcagg acgccgagtt cacaccgccc aagtggttct
    19801 tcaaggggtt cggcgactgg gcccggctgc ccggcgagcc cctgaccgtc cccgcccgcc
    19861 cggtcgcgct catcgaggag ccggaggtcg tgctcgtgta cgtcaacgac gccgacggca
    19921 cgccgcacta cgccggttac accttcggca acgacctgtg cgacatcggc ctgcaccgca
    19981 aggaccctgg ctacaacccg tactgcaagc tgtgcgacac cgcgctcgcg ccctggctgt
    20041 tcctcggccc gccgccgcgc tcggcgaccg gccgcgtcac catcgtgcgg gacggcgcga
    20101 ccgcctggga gggcagcttc gactgcggcg gcgacgcgct gtacttccgg gtccgggaca
    20161 tggtcgacca cctgttctcc ttcccggcgg tgcgccgacc cggcctggtc aactacgtgc
    20221 tgctcggcgc ggacgaggcc agcttccacg acggcttccg gatcgccgac ggcgaccgca
    20281 tcggcatcga cgtcaagagc cacggcgtca ccttcgagaa cacggtgcgg tacgtctccc
    20341 cggcccccgc cgccgcgctc ccggcctcat gagcggcccg cccgccgccg gacgcaaaca
    20401 ggtacacctg gcggcccagc tgcccggcat ccacaacgtg accgtctggt cggacccgcg
    20461 cgccaggagc cagatcgcct tcgactcctt cctgcacctc gcgcagaccg ccgaacgcgg
    20521 ccggttcgac ttcttcttcc tggccgaggg cctcagactg cgcgagcaca aggggcagct
    20581 gtacgacctg gacgtggtcg gccggccgga caacctcacc cagctgagcg ccctggccgc
    20641 ggtcaccacc cggctcggac tcgccgcgac cgtcaacgcc accttcaacg agccctacga
    20701 ggtggcgcgc cggctggcca ccctcgacca cctcagcgcc gggcgcaccg cctggaacgt
    20761 ggtcaccagc tccgacgcct tcaccggcga gaacttccgg cgcggtggtt tcctcgccga
    20821 ggccgaccgc tacgcacgcg cggccgagtt cctggcgacc gcgcgcgagc tgtgggacag
    20881 ctgggccgac ggcgatgtgc gcgccgacgc cgtggccggg gcgtacctcc ggcccggcgc
    20941 cggccgtttc gcgcaccgcg ggcggcactt cgacatctcc ggccgcttca ccacccctcg
    21001 ccctccacag gggcacccgg tgatcatcca ggcgggcgac tccgacacgg gccgcgagtt
    21061 cgccgccgcc gaggccgacg tcgtcttcag caagtacaac cggctcgacc aggcccgcag
    21121 cttctaccgt gacgtcaagg gacgcctggc gcggcacggt cgcaccccgg accggctgaa
    21181 gatcctgccc acggccaccg tggtggtggc ggacagcgac gcggaggctg ccgcctacgc
    21241 cgacgagatc acccgcgccc aggtgagccc gcagaccgcg atcgcccacc tggaggccgt
    21301 ctggggccgt gacctgtccg gctacgaccc cgacggcccg ctgccggaca tcgaccccga
    21361 ccccgactcg ctgacgctga agggccattc actgttccgc cggggccgcg ccgagaccgc
    21421 gcggcgctgg cgggccctcg ccgagcggcg cggcctgagt atccgcgaac tggtcatcga
    21481 gatcagcggc ggccagacct tcgtcggcgc cccgcgcacc gtcgccgacg cgatcgacca
    21541 cttcgtgcag accggcggcg ccgacggctt cgtcctcgtc ccgcacctga cccctaccgg
    21601 cctggacgac ttcgtggccc gggtcgttcc actgctccag gaagagggcg tgttccggcc
    21661 ggactacacg agcaggacgc tccgtgacca cctgggcctg ccgcacgaca ggggagaaga
    21721 cacggcagac ccggctgccg aggaggaggc ctcgtgaccg catccccgct gcacctcgcc
    21781 gtcgccctgg acggcgccgg ctggcacccg gcggcctggc gggccgagga cgcccggccc
    21841 ggcgcgctgt tcaccgccca gtactgggca gacctggtca cggaagccga gcacggcatg
    21901 ctcgacttcg tcaccttcga ggatgcgctc ggcatacagt ccgccgcctt ccaccggccc
    21961 gacgaccgca ccgaccaggt gcgcggcagt ctggacgcgg tcctgctcgc ggctcgcatg
    22021 gcaccgctca ccacgcacat cggcctggtc ccgaccgcga acgtcaccca tacggagccg
    22081 ttccacgtag ccaccggcat cgccaccctc gaccatgcga gcaaaggccg ggccggctgg
    22141 cgcccgcaga tcgccgcgcg cgccgccgac gccacccact tcggccgccg tacgacgccg
    22201 cagctcaccg acgacgacgt gcgcgacccg gagcgcatcg gccggcggct gcgcccgctg
    22261 ttcgacgagg ccaccgacgt ggtggaggtc gcccggcggc tgtgggacag ctgggaggac
    22321 gacgcggaga tccgggacgc ggccaccggc cgcttcatcg accgcggcaa ggtccaccac
    22381 atcgacttcg cgggcgccca cttcggtgtc cggggccctt cgatcatccc acgcccgccg
    22441 cagggacaac cgcttgtgac gagcctggcg cacgccatgg tcccgtacga gttcgcgacg
    22501 cgctcgtgcg acgtcgtgta cgtcacgccg cacgaccggg cgggggccgc ggcgatcgtt
    22561 gcccaggtgg acgaagccgc cggccgctcc ggccgcgaca tgcgggcctg gccactgctc
    22621 cggttcgcgg aactcctcgt cttcctggac gccgagccgc gcgccgccac gcaccgcaag
    22681 acccacctcg attccctcga cggcgccgaa ctcacctccg atgccgaggt gttcaccggc
    22741 actcccggcg aactcgccga cctgctgctg gactggcgcg aggcggggct cgacggcttc
    22801 cggattcgcc ccggcacgct gccgcacgac ctcgttcaga tcactcgcgg gctggtaccc
    22861 gagctgcagc ggcgcggagc gttccgcacc gcgtacgacg cgacgacgct gcgcggccac
    22921 ctgtgcctgg cgcgccccaa cagccgctat tcgcaggaga ggcagaccag aaagtgacgg
    22981 ttctcacgca ggcccgcccg gcagcgagac aactcacctt catcgctgcc acccgcctgc
    23041 tgccgtcctt ctgtatcctc gcgtcgcatc tgtccttcga gcaggtcttc aaggaccgga
    23101 cggtgcagga gacgtactac cgcatcttca acccggcggg cttcaacgcg gtgtcgttct
    23161 tcatcgtcct cagcggcttc atcctgacgt ggatatccgc agagcgcccg ccggaccgcg
    23221 gcttccgggc ccgccgactg ctgcgcatcc tgccggtgca cttcctgacc tgggccgtga
    23281 tcgtgtgcgc cttcgccgcc accttctcgg ccaccggcct gttcgccacg ctcaccctcc
    23341 tgcaaggctg gttcccggac cacggcatct actgggcggc caacgccccg gcgtggaccc
    23401 tgtcgaccga actcgtcctg tacgcggtgt tcccgaccgc gtacaggttc ctggtccgcc
    23461 gcggtgacca gttcctgttc ggcctgctga ccggtctgat cgcggtcgtg gtgctgttgc
    23521 cgctggctct gcaactcctt ccggacggca cgacgttcgc caacgcagcg ttcacggagc
    23581 gcggccacct cgtccgtgtc tccgagtgga aatactggct cgtctacgtc tttccgctca
    23641 ctcgcgtcct ggaggcgctg tgcggcatgg tggtctgcct gctggtgtcg cgcggcaggt
    23701 ggacgcgcaa agtccgggtg cccaccgcac tgctcgtgtc ggcggtggtg gtcgaggagc
    23761 tgtgggcgcc ggtcctgttc gacctgacgg cgttgacgat cgtcccgatc gccctgctca
    23821 tcggcgcctt ggcagccaag gagatcggcc gttggaatgc cccaggtgct acggagaacc
    23881 gcgccgtcgc ccgcgtctcg gcctacggca agtacacctt cggtatttac atgtaccagt
    23941 gggccttcat catggtctgc cagcggtatg tgcacccctg gggcaactcg gtcgccgggg
    24001 gcgtgctctt ggtgatcgcc ttctacgcgc tgtgcgtcgc cgtctccatg gtctcctacc
    24061 gcttcgtcga gaccccggtc aaccgtttca tgaagcctgc catcgctgcg tacacgaagc
    24121 ggtgacccct tgcgcggctt gtcggggcgg acttgcggtg aacatcatcg aatgctgaag
    24181 tgaaccgcgt gacgggtggg gtggcgatgg gtggagcggc acgggtgcgc gtgccggtgg
    24241 gtgaggatgc ggagcgatgg gtcacacggg tggggtgccg ccgtgtgctg ttcatcgtgc
    24301 acaacgtgac gtccgctacg cggctgctgg acgtgcttcc gctgttcgac ggcgacctgc
    24361 gcgtccagat ggccgccacc tgcaccggct cgtccccgtt cctcgccggg gtgcccgagc
    24421 tgctggcacg ggcggggctg ccggtcctgc cctgggaaca ggccaaggag acgccgttcg
    24481 acctggtggt gtccgccagt tacggcggtg aactcgcttc cgtgcaaggt aagttggcgg
    24541 tgctgtcaca cggggtcgga tacaataaaa ggctggctac accggacacc ggacaccgga
    24601 caccggacac cggacaccgg acacccgtcg ccctcgtccc cgcccgtctt cgggctgtcg
    24661 cccgactggc tcctggaaga cgggcgtccc ctcgccagcg ccaccgtcct gtcccaccca
    24721 gaacagctgg agcggctgcg ctcggcctgt ccggaggcgg cgcccaccgc ggtgctcgcc
    24781 ggggacccgt gctatgaccg catgcttgcc gcgctccccc aacgtgccgc cttccgccgt
    24841 gcgttgggcg tgggcccggg ccagcggctg atcgtcgtca gctcgacctg ggcgccccgt
    24901 tccctcttcg gcggagccgc ggagccggag gcggatgatc tgctgccctg gctgctgtcc
    24961 cgcctctcgg ccgagctgcc ggccgacgag taccggaccg tcgcggtcct gcatccgaac
    25021 atctggtacg gccatgggcc cgggcaggtc cgtgcctggc tggacaacgc gcggcgggcc
    25081 ggcctcgacg cgataccgcc gctcgacggg tggcaacagg ccctgatcgc cgccgactgt
    25141 gtcctggggg atcattcgag cgtcacctac tacgcggcgt ccataggcat ccccgtcgtc
    25201 ctcgggtcgt tcccccagca ggacctcgac ccgctgtcac cggtcgccgc cctcggccgt
    25261 accgctcccc gactcgttcg ccgaggcagc ctgcgggcac agatcgacca ggtcatcgcg
    25321 gcgcacgacc ccggccggta caaggagctc gcggagcaga ccagttcggc accgggcgag
    25381 tcggccgctc tgctgcgccg cctgttctac ggcctcatgg agctgcccga gccggaccgg
    25441 cactccgcgc tgctcgaccc gctgccgctg ccgccgtacc tgcccgcccg ccgtaccgcc
    25501 ccggtccgcg tcctcgtcgg cggtatcggc tcgcatccgc cggaggtctc cgtcgtccgg
    25561 tacgccgtcg cgggcgccgg gcccggaccg gcggtgtgtg ccgactccgc gcacacagtc
    25621 gtggacgagg agacgcggga gaccgggcgg ctgggcatcg ccgacgtcgt cgtacggtac
    25681 gcggccgggg acgatccacg gctcgggccg cccgccgcct ggacggcgga ggcgctggac
    25741 cgctacccgt actgcgggct ggccgcctat gtcgacgggc cggaccgctg tgtcgtacgc
    25801 acccgggacg gtgacctcgt gcggctgtcc gccgcagcgg ccctcgacgg ccgggccgac
    25861 ctgtgcgatc ccgccgccta cgcctccgcg ctgcacgcct ggctcgcgag cggccggagc
    25921 ctggagcggg ccctccccgg gatcaccgta cgcaccggtg ccaccgccca tcgggtcgcc
    25981 gtggagccgc tcgccccgtg agccgggtcc tcacgccgcc agctcggcca ggcgcgcccg
    26041 tacgcgcgcc aggccgatgt ggttcccgtg ctcctcgtag gacacggccg cggtacgcag
    26101 gtcctccgtc tcctcggccg ggcggtccga ccgtcggtga cagcgggccc gcgcctcgac
    26161 ggcgtcggcc agttgcagtc ccgcgcccgc ctcggtcatc gccttgacgg cctcgtccag
    26221 gcacacgcgc gcctgctccg cgtcccccgc gtccaggtgg gcgtcgccca gactcatata
    26281 gacccggccc gcgttgtagg catcgccacc gcccggcagc cggcggaacc gcgccagggc
    26341 gtcgttcagc cgggcgatgg cggcggcgaa gtccccccgc ttggtctggg cgcggccgat
    26401 gtggtgggcc agcagggccg tggcgcgcgg cacgtcctcc gctccgtcct cgcccgggcc
    26461 gatacggcgc agaatctcct gcgcctcctc gaagcaccgc tgggccgccc cgaactccca
    26521 ctgcctgagg cggagcagcc ccagcgcctc gacggcggtc gcctcgccgc ggtgatggcc
    26581 gcaggcccgg tccgcggccc gcgcctgtgt gagggcatcc gcggcctccg tcacctgccc
    26641 ggctcccatg tgggcgaagg ccagttgcgt ccacatgcgg cccacggcgc gcgggtcgcc
    26701 gaactcctcc gcgccgcgcc gggcggcctc gacgccgagc aggtgtgtgt cgatccactg
    26761 ggcgtggaag ccgagcagca gatgcaggcc ccacatcgcc tcgcacagtt gccagacgag
    26821 gtcgtcgaag ccgtggtgtg cggcggcccg gatgacggcc gcgaggttct cccgctcggc
    26881 gcgcaggtcg gccagggctc gcttgccgtc ctcggggtcg cggtgttccg ggacggtgag
    26941 cgcctggtag gcggggccga gccgccagcg gagcggcatg acccggaagt cgagtcccgc
    27001 cgcgaagcgc agatgcgcga ccgccacgcg gcggacggcg gccgccatcc ggccgtgccc
    27061 gtcctcggcc tccgcgagcc cgtgggcgtg cgcccgggtc aggtcgtgga accggtagcg
    27121 ctcctcgccg acctcctcca gcagatgcac ccgggccagc ctctccagca gcgcccgcgc
    27181 ctcgtcctcg ctcaccccgg cggcctgtgc cgcgcacagc acggtgacgg tcggccaggg
    27241 ccacaccgcg atcgcccggt agaacgcagc gcagtcgggg gcgagttggc cgtaggagac
    27301 gtcctggacg gcgcgcacgg gatcggccga ggcgtcgggg gccggttctc ccatgagggc
    27361 acctcccagg tcatggccgt ggctacggtc ggacagctgc cgcgcgaccc gttcccacgt
    27421 caggtgttcc cggacggcga ggccggcgcc cgtggtgcac agggcgaggg gaatcccacc
    27481 tgtgccctgc
//
